locus-tag	class	description
A16R_00020	COG0592	DNA-directed DNA polymerase activity
A16R_00030	COG2501	S4 domain
A16R_00050	COG0187	DNA topoisomerase II activity
A16R_00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A16R_00120	COG0516	GMP reductase activity
A16R_00120	COG0517	IMP dehydrogenase activity
A16R_00130	COG1686	Belongs to the peptidase S11 family
A16R_00190	COG1428	Deoxynucleoside kinase
A16R_00200	COG1428	Deoxynucleoside kinase
A16R_00210	COG1335	isochorismatase
A16R_00220	COG0590	tRNA wobble adenosine to inosine editing
A16R_00230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A16R_00340	COG1982	Orn Lys Arg decarboxylase major
A16R_00360	COG0470	DNA polymerase III
A16R_00370	COG1774	PSP1 C-terminal conserved region
A16R_00390	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A16R_00410	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A16R_00420	COG2002	toxin-antitoxin pair type II binding
A16R_00430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_00430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_00440	COG0084	hydrolase, TatD family'
A16R_00450	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A16R_00480	COG4466	Protein conserved in bacteria
A16R_00510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A16R_00520	COG0251	oxidation-reduction process
A16R_00550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A16R_00560	COG0193	aminoacyl-tRNA hydrolase activity
A16R_00580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A16R_00590	COG2002	toxin-antitoxin pair type II binding
A16R_00600	COG2244	polysaccharide biosynthetic process
A16R_00610	COG3956	TIGRFAM MazG family protein
A16R_00620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A16R_00660	COG1098	S1 RNA binding domain
A16R_00690	COG2208	phosphoserine phosphatase activity
A16R_00700	COG0037	tRNA processing
A16R_00720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A16R_00750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A16R_00760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A16R_00770	COG0512	Glutamine amidotransferase of anthranilate synthase
A16R_00780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A16R_00790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A16R_00800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A16R_00810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A16R_00820	COG1396	sequence-specific DNA binding
A16R_00830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A16R_00890	COG3880	PFAM UvrB UvrC protein
A16R_00910	COG0542	response to heat
A16R_00920	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A16R_00940	COG4956	integral membrane protein (PIN domain superfamily)
A16R_00980	COG1045	serine acetyltransferase
A16R_01010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A16R_01020	COG3688	RNA-binding protein containing a PIN domain
A16R_01040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A16R_01050	COG0250	Participates in transcription elongation, termination and antitermination
A16R_01100	COG2813	Specifically methylates the guanine in position
A16R_01140	COG1358	cellular component organization or biogenesis
A16R_01350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A16R_01400	COG0201	protein transport
A16R_01420	COG0024	Methionine aminopeptidase
A16R_01440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A16R_01500	COG1122	ATPase activity
A16R_01510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A16R_01530	COG0101	tRNA pseudouridine synthase activity
A16R_01570	COG0860	N-Acetylmuramoyl-L-alanine amidase
A16R_01580	COG0489	protein tyrosine kinase activity
A16R_01600	COG2194	sulfuric ester hydrolase activity
A16R_01610	COG0726	polysaccharide deacetylase
A16R_01780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A16R_01790	COG4856	YbbR-like protein
A16R_01810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A16R_01820	COG0596	Alpha beta hydrolase
A16R_01870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A16R_01880	COG4946	Tricorn protease homolog
A16R_01880	COG1506	peptidase
A16R_01880	COG0823	Involved in the tonB-independent uptake of proteins
A16R_01960	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_01970	COG2011	ABC-type metal ion transport system permease component
A16R_01980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A16R_01990	COG1464	Belongs to the NlpA lipoprotein family
A16R_02020	COG0277	FAD linked oxidase domain protein
A16R_02030	COG2271	Major facilitator Superfamily
A16R_02050	COG2814	Major facilitator Superfamily
A16R_02080	COG0601	transmembrane transport
A16R_02090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A16R_02100	COG0444	Belongs to the ABC transporter superfamily
A16R_02110	COG4608	Belongs to the ABC transporter superfamily
A16R_02120	COG4166	transmembrane transport
A16R_02140	COG2207	Transcriptional regulator
A16R_02170	COG4166	transmembrane transport
A16R_02180	COG4166	transmembrane transport
A16R_02190	COG0656	L-ascorbic acid biosynthetic process
A16R_02200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A16R_02230	COG4149	molybdate abc transporter
A16R_02240	COG0725	ABC transporter, periplasmic molybdate-binding protein
A16R_02250	COG0725	ABC transporter, periplasmic molybdate-binding protein
A16R_02260	COG1910	domain protein
A16R_02270	COG0583	DNA-binding transcription factor activity
A16R_02280	COG0697	spore germination
A16R_02300	COG0204	Acyl-transferase
A16R_02320	COG1609	Transcriptional regulator
A16R_02340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_02390	COG5298	Protein conserved in bacteria
A16R_02450	COG0488	(ABC) transporter
A16R_02490	COG0747	negative chemotaxis
A16R_02500	COG0601	transmembrane transport
A16R_02520	COG0444	Belongs to the ABC transporter superfamily
A16R_02530	COG4608	Belongs to the ABC transporter superfamily
A16R_02580	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A16R_02590	COG0179	Fumarylacetoacetate (FAA) hydrolase
A16R_02610	COG2814	Major facilitator Superfamily
A16R_02640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A16R_02660	COG4294	response to UV
A16R_02670	COG0457	Tetratricopeptide repeat
A16R_02670	COG0705	Rhomboid family
A16R_02690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A16R_02700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A16R_02710	COG0864	Transcriptional regulator
A16R_02720	COG2337	Toxic component of a toxin-antitoxin (TA) module
A16R_02730	COG2183	response to ionizing radiation
A16R_02910	COG0802	atpase or kinase
A16R_02920	COG1214	PFAM Peptidase M22, glycoprotease
A16R_02930	COG0456	acetyltransferase
A16R_02940	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A16R_02950	COG0488	(ABC) transporter
A16R_02980	COG1266	CAAX protease self-immunity
A16R_03050	COG5002	protein histidine kinase activity
A16R_03110	COG2226	methyltransferase
A16R_03200	COG1968	undecaprenyl-diphosphatase activity
A16R_03280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A16R_03290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A16R_03330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A16R_03370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A16R_03390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A16R_03410	COG0151	Belongs to the GarS family
A16R_03460	COG0210	DNA helicase
A16R_03480	COG4851	CamS sex pheromone cAM373 precursor
A16R_03520	COG1335	isochorismatase
A16R_03530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A16R_03540	COG2011	ABC-type metal ion transport system permease component
A16R_03550	COG1464	Belongs to the NlpA lipoprotein family
A16R_03600	COG1846	Transcriptional regulator
A16R_03650	COG1597	lipid kinase activity
A16R_03660	COG0546	phosphoglycolate phosphatase activity
A16R_03670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A16R_03690	COG1012	belongs to the aldehyde dehydrogenase family
A16R_03700	COG2076	Multidrug Resistance protein
A16R_03710	COG2309	aminopeptidase activity
A16R_03740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_03750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A16R_03760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A16R_03780	COG4807	Protein conserved in bacteria
A16R_03840	COG1473	amidohydrolase
A16R_03870	COG0450	alkyl hydroperoxide reductase
A16R_03880	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A16R_03900	COG0235	Class ii aldolase
A16R_03910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_03930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_03960	COG0166	Belongs to the GPI family
A16R_04030	COG5002	protein histidine kinase activity
A16R_04070	COG3541	Predicted nucleotidyltransferase
A16R_04080	COG2814	Major facilitator Superfamily
A16R_04090	COG0723	plastoquinol--plastocyanin reductase activity
A16R_04090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A16R_04110	COG0765	amino acid transport
A16R_04120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A16R_04140	COG0840	transmembrane signaling receptor activity
A16R_04150	COG0840	transmembrane signaling receptor activity
A16R_04160	COG0366	Alpha amylase catalytic
A16R_04170	COG1263	PTS System
A16R_04170	COG2190	(PTS) system
A16R_04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_04240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A16R_04270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A16R_04290	COG1116	anion transmembrane transporter activity
A16R_04410	COG2270	Major facilitator Superfamily
A16R_04440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A16R_04470	COG2310	stress, protein
A16R_04480	COG2310	stress, protein
A16R_04490	COG2310	stress, protein
A16R_04500	COG0861	Integral membrane protein TerC family
A16R_04520	COG3853	Toxic anion resistance protein (TelA)
A16R_04550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A16R_04570	COG1295	ribonuclease BN
A16R_04580	COG2217	Heavy metal translocating P-type atpase
A16R_04590	COG0697	spore germination
A16R_04640	COG0586	Pfam SNARE associated Golgi protein
A16R_04670	COG3871	stress protein (general stress protein 26)
A16R_04680	COG0387	Pfam Sodium calcium exchanger
A16R_04700	COG0535	radical SAM domain protein
A16R_04750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A16R_04760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A16R_04770	COG0582	viral genome integration into host DNA
A16R_04820	COG1396	sequence-specific DNA binding
A16R_04890	COG1484	DNA-dependent DNA replication
A16R_05060	COG0582	viral genome integration into host DNA
A16R_05330	COG0101	tRNA pseudouridine synthase activity
A16R_05350	COG3829	transcription factor binding
A16R_05370	COG0833	amino acid
A16R_05380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A16R_05430	COG2066	Belongs to the glutaminase family
A16R_05450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_05450	COG1263	PTS System
A16R_05460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A16R_05490	COG0463	Glycosyl transferase, family 2
A16R_05520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A16R_05520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A16R_05550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A16R_05590	COG1228	amidohydrolase
A16R_05600	COG1090	epimerase
A16R_05660	COG1988	membrane-bound metal-dependent
A16R_05670	COG1194	a g-specific adenine glycosylase
A16R_05740	COG1132	(ABC) transporter
A16R_05750	COG4129	membrane
A16R_05800	COG4555	ABC transporter
A16R_05840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A16R_05850	COG0735	belongs to the Fur family
A16R_06080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A16R_06120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A16R_06140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A16R_06160	COG2766	serine protein kinase
A16R_06200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A16R_06220	COG1585	Membrane protein implicated in regulation of membrane protease activity
A16R_06230	COG2268	Band 7 protein
A16R_06250	COG3290	protein histidine kinase activity
A16R_06280	COG2851	Citrate transporter
A16R_06320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A16R_06330	COG3842	ATPase activity
A16R_06340	COG1175	transmembrane transport
A16R_06350	COG0395	ABC-type sugar transport system, permease component
A16R_06370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A16R_06380	COG0745	RESPONSE REGULATOR receiver
A16R_06390	COG5002	protein histidine kinase activity
A16R_06410	COG4990	cell redox homeostasis
A16R_06430	COG3290	protein histidine kinase activity
A16R_06440	COG4565	transcriptional regulatory protein
A16R_06450	COG3493	citrate carrier protein
A16R_06460	COG0281	malic enzyme
A16R_06490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_06510	COG5002	protein histidine kinase activity
A16R_06520	COG0745	RESPONSE REGULATOR receiver
A16R_06540	COG0456	acetyltransferase
A16R_06540	COG0454	-acetyltransferase
A16R_06550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A16R_06560	COG3383	formate dehydrogenase (NAD+) activity
A16R_06580	COG2427	Protein of unknown function (DUF1641)
A16R_06610	COG0531	amino acid
A16R_06620	COG0640	Transcriptional regulator
A16R_06630	COG2217	Heavy metal translocating P-type atpase
A16R_06640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A16R_06670	COG3227	Zinc metalloprotease (Elastase)
A16R_06710	COG2720	vancomycin resistance protein
A16R_06720	COG1316	TRANSCRIPTIONal
A16R_06730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_06750	COG1253	flavin adenine dinucleotide binding
A16R_06760	COG1027	Aspartate ammonia-lyase
A16R_06770	COG1620	l-lactate permease
A16R_06800	COG3104	oligopeptide transport
A16R_06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_06820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_06830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_06850	COG2226	methyltransferase
A16R_06860	COG0156	8-amino-7-oxononanoate synthase activity
A16R_06870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A16R_06890	COG4548	von Willebrand factor, type A
A16R_06900	COG0714	Associated with various cellular activities
A16R_06910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A16R_06950	COG0531	amino acid
A16R_06960	COG2188	Transcriptional regulator
A16R_06970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_06970	COG1263	PTS System
A16R_06980	COG0366	Alpha amylase catalytic
A16R_07020	COG0697	spore germination
A16R_07040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A16R_07050	COG1115	amino acid carrier protein
A16R_07060	COG1126	abc transporter atp-binding protein
A16R_07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A16R_07080	COG0765	amino acid transport
A16R_07090	COG0765	amino acid transport
A16R_07100	COG0833	amino acid
A16R_07150	COG2378	regulation of single-species biofilm formation
A16R_07160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A16R_07170	COG5002	protein histidine kinase activity
A16R_07210	COG0659	secondary active sulfate transmembrane transporter activity
A16R_07240	COG0747	negative chemotaxis
A16R_07260	COG0601	transmembrane transport
A16R_07270	COG4608	Belongs to the ABC transporter superfamily
A16R_07290	COG2271	Major facilitator Superfamily
A16R_07300	COG1846	Transcriptional regulator
A16R_07310	COG0477	Major facilitator Superfamily
A16R_07320	COG0477	Major facilitator Superfamily
A16R_07330	COG1609	Transcriptional regulator
A16R_07340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A16R_07360	COG1129	ABC transporter
A16R_07370	COG1172	Belongs to the binding-protein-dependent transport system permease family
A16R_07380	COG1879	ABC-type sugar transport system periplasmic component
A16R_07390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A16R_07440	COG1063	alcohol dehydrogenase
A16R_07470	COG3568	Endonuclease Exonuclease Phosphatase
A16R_07520	COG1968	undecaprenyl-diphosphatase activity
A16R_07530	COG0840	transmembrane signaling receptor activity
A16R_07540	COG1388	LysM domain
A16R_07540	COG3584	3D domain protein
A16R_07550	COG1476	TRANSCRIPTIONal
A16R_07580	COG3104	oligopeptide transport
A16R_07590	COG1114	Component of the transport system for branched-chain amino acids
A16R_07620	COG1113	amino acid transport
A16R_07630	COG2252	PERMEase
A16R_07680	COG0475	glutathione-regulated potassium exporter activity
A16R_07680	COG0569	domain protein
A16R_07710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A16R_07720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A16R_07730	COG4990	cell redox homeostasis
A16R_07760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A16R_07770	COG0697	spore germination
A16R_07780	COG0531	amino acid
A16R_07840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A16R_07850	COG1918	ferrous iron import across plasma membrane
A16R_07850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A16R_07860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A16R_07870	COG0573	inorganic phosphate transmembrane transporter activity
A16R_07880	COG0581	inorganic phosphate transmembrane transporter activity
A16R_07900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A16R_08130	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A16R_08180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A16R_08190	COG1116	anion transmembrane transporter activity
A16R_08200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A16R_08210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A16R_08220	COG0352	thiamine-phosphate diphosphorylase activity
A16R_08230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A16R_08240	COG2104	thiamine diphosphate biosynthetic process
A16R_08260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A16R_08270	COG0351	phosphomethylpyrimidine kinase
A16R_08340	COG2205	protein histidine kinase activity
A16R_08350	COG2814	Major facilitator Superfamily
A16R_08360	COG1846	Transcriptional regulator
A16R_08390	COG2252	PERMEase
A16R_08400	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_08440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A16R_08450	COG1621	beta-fructofuranosidase activity
A16R_08460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_08460	COG1263	PTS System
A16R_08470	COG1609	Transcriptional regulator
A16R_08490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A16R_08500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A16R_08590	COG0778	Nitroreductase
A16R_08600	COG2719	SpoVR family
A16R_08660	COG0446	pyridine nucleotide-disulphide oxidoreductase
A16R_08670	COG1937	Protein conserved in bacteria
A16R_08680	COG0425	Belongs to the sulfur carrier protein TusA family
A16R_08680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_08690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_08690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_08700	COG0425	Belongs to the sulfur carrier protein TusA family
A16R_08710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_08730	COG2210	Belongs to the sulfur carrier protein TusA family
A16R_08740	COG0730	response to heat
A16R_08760	COG1316	TRANSCRIPTIONal
A16R_08770	COG0604	alcohol dehydrogenase
A16R_08790	COG1283	sodium-dependent phosphate transmembrane transporter activity
A16R_08830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A16R_08830	COG3711	transcriptional antiterminator
A16R_08840	COG1447	Phosphotransferase system cellobiose-specific component IIA
A16R_08850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A16R_08910	COG0577	efflux transmembrane transporter activity
A16R_08920	COG1136	(ABC) transporter
A16R_08940	COG5522	Integral membrane protein (intg_mem_TP0381)
A16R_08980	COG1114	Component of the transport system for branched-chain amino acids
A16R_08990	COG3546	catalase activity
A16R_09060	COG0586	Pfam SNARE associated Golgi protein
A16R_09130	COG0531	amino acid
A16R_09140	COG0475	glutathione-regulated potassium exporter activity
A16R_09160	COG1737	Transcriptional regulator
A16R_09180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_09180	COG1263	PTS System
A16R_09200	COG2259	Doxx family
A16R_09230	COG0697	spore germination
A16R_09240	COG1522	sequence-specific DNA binding
A16R_09260	COG2076	Multidrug Resistance protein
A16R_09270	COG2076	Multidrug Resistance protein
A16R_09280	COG1309	transcriptional regulator
A16R_09290	COG2814	Major facilitator Superfamily
A16R_09300	COG1733	regulation of RNA biosynthetic process
A16R_09320	COG2249	NAD(P)H dehydrogenase (quinone) activity
A16R_09330	COG4533	DNA binding
A16R_09340	COG2211	Major facilitator Superfamily
A16R_09360	COG0693	protein deglycase activity
A16R_09370	COG0693	protein deglycase activity
A16R_09370	COG0753	catalase activity
A16R_09390	COG0531	amino acid
A16R_09400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A16R_09420	COG1012	belongs to the aldehyde dehydrogenase family
A16R_09430	COG1132	(ABC) transporter
A16R_09460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A16R_09470	COG0765	amino acid transport
A16R_09480	COG1126	abc transporter atp-binding protein
A16R_09510	COG0189	ligase activity
A16R_09570	COG0028	Belongs to the TPP enzyme family
A16R_09580	COG3527	Alpha-acetolactate decarboxylase
A16R_09610	COG0561	phosphatase activity
A16R_09690	COG0659	secondary active sulfate transmembrane transporter activity
A16R_09730	COG0653	protein targeting
A16R_09740	COG2244	polysaccharide biosynthetic process
A16R_09760	COG0860	N-Acetylmuramoyl-L-alanine amidase
A16R_09780	COG4196	transglutaminase domain protein
A16R_09810	COG1696	Membrane protein involved in D-alanine export
A16R_09850	COG1024	Enoyl-CoA hydratase
A16R_09880	COG1363	Peptidase, m42
A16R_09920	COG3938	Belongs to the proline racemase family
A16R_10000	COG0601	transmembrane transport
A16R_10010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A16R_10040	COG4608	Belongs to the ABC transporter superfamily
A16R_10100	COG0477	Major facilitator Superfamily
A16R_10110	COG3290	protein histidine kinase activity
A16R_10120	COG4565	transcriptional regulatory protein
A16R_10130	COG3181	Tripartite tricarboxylate transporter family receptor
A16R_10200	COG4978	Transcriptional regulator
A16R_10200	COG0789	Transcriptional regulator
A16R_10230	COG0305	Participates in initiation and elongation during chromosome replication
A16R_10300	COG0477	Major facilitator Superfamily
A16R_10390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A16R_10390	COG3320	Male sterility
A16R_10440	COG1183	phosphatidylcholine synthase activity
A16R_10480	COG2376	Dihydroxyacetone kinase
A16R_10500	COG2376	Dihydroxyacetone kinase
A16R_10510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A16R_10520	COG1959	2 iron, 2 sulfur cluster binding
A16R_10590	COG2770	Histidine kinase
A16R_10590	COG3437	response regulator, receiver
A16R_10690	COG3237	CsbD-like
A16R_10740	COG1191	sigma factor activity
A16R_10760	COG2208	phosphoserine phosphatase activity
A16R_10770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A16R_10780	COG2198	Histidine kinase
A16R_10780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A16R_10780	COG0784	Response regulator, receiver
A16R_10780	COG2205	protein histidine kinase activity
A16R_10830	COG0393	Putative heavy-metal-binding
A16R_10900	COG0420	3'-5' exonuclease activity
A16R_10910	COG4717	serine-type aminopeptidase activity
A16R_10950	COG1309	transcriptional regulator
A16R_10960	COG2814	Major facilitator Superfamily
A16R_10970	COG0346	lactoylglutathione lyase activity
A16R_10980	COG0346	lactoylglutathione lyase activity
A16R_10990	COG0457	Tetratricopeptide repeat
A16R_11010	COG2267	carboxylic ester hydrolase activity
A16R_11050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A16R_11090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A16R_11170	COG0477	Major facilitator Superfamily
A16R_11180	COG0477	Major facilitator Superfamily
A16R_11200	COG3973	AAA domain
A16R_11210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A16R_11250	COG4980	gas vesicle protein
A16R_11260	COG0537	adenosine 5'-monophosphoramidase activity
A16R_11270	COG1131	(ABC) transporter
A16R_11280	COG4473	ABC transporter
A16R_11310	COG1309	transcriptional regulator
A16R_11330	COG3402	PFAM membrane-flanked domain
A16R_11350	COG3428	Bacterial PH domain
A16R_11430	COG3402	PFAM membrane-flanked domain
A16R_11440	COG3428	Bacterial PH domain
A16R_11450	COG2329	Antibiotic biosynthesis monooxygenase
A16R_11460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A16R_11470	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A16R_11560	COG1309	transcriptional regulator
A16R_11570	COG1511	domain protein
A16R_11620	COG1609	Transcriptional regulator
A16R_11640	COG1234	tRNA 3'-trailer cleavage
A16R_11650	COG0095	Lipoate-protein ligase
A16R_11670	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_11730	COG3209	COG3209 Rhs family protein
A16R_11830	COG1408	metallophosphoesterase
A16R_11840	COG1078	dGTPase activity
A16R_11870	COG1595	DNA-templated transcription, initiation
A16R_11880	COG3708	Transcriptional regulator
A16R_11880	COG2207	Transcriptional regulator
A16R_11910	COG2205	protein histidine kinase activity
A16R_11920	COG0745	RESPONSE REGULATOR receiver
A16R_11970	COG0501	Belongs to the peptidase M48B family
A16R_11980	COG0840	transmembrane signaling receptor activity
A16R_11990	COG0697	spore germination
A16R_12030	COG0497	DNA recombination
A16R_12040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A16R_12050	COG2224	Isocitrate lyase
A16R_12070	COG1278	Cold shock
A16R_12100	COG4903	ComK protein
A16R_12110	COG0398	Pfam SNARE associated Golgi protein
A16R_12130	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A16R_12140	COG1074	ATP-dependent DNA helicase activity
A16R_12230	COG0179	Fumarylacetoacetate (FAA) hydrolase
A16R_12310	COG0753	catalase activity
A16R_12370	COG2996	Protein conserved in bacteria
A16R_12390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A16R_12410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_12440	COG0561	phosphatase activity
A16R_12470	COG0542	response to heat
A16R_12490	COG2267	carboxylic ester hydrolase activity
A16R_12520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_12530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A16R_12540	COG5504	Zn-dependent protease
A16R_12560	COG0180	Tryptophanyl-tRNA synthetase
A16R_12580	COG4166	transmembrane transport
A16R_12590	COG0601	transmembrane transport
A16R_12600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A16R_12610	COG0444	Belongs to the ABC transporter superfamily
A16R_12620	COG4608	Belongs to the ABC transporter superfamily
A16R_12630	COG0534	Mate efflux family protein
A16R_12680	COG1393	Belongs to the ArsC family
A16R_12690	COG0861	Integral membrane protein TerC family
A16R_12700	COG4862	establishment of competence for transformation
A16R_12710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A16R_12770	COG2346	COG2346, Truncated hemoglobins
A16R_12780	COG4116	CYTH
A16R_12800	COG2357	RelA SpoT domain protein
A16R_12810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A16R_12820	COG0564	pseudouridine synthase activity
A16R_12870	COG0772	Belongs to the SEDS family
A16R_12880	COG1216	Glycosyl transferase, family 2
A16R_12930	COG0457	Tetratricopeptide repeat
A16R_12930	COG0463	Glycosyl transferase, family 2
A16R_12970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A16R_13000	COG1091	dTDP-4-dehydrorhamnose reductase activity
A16R_13110	COG2153	protein acetylation
A16R_13120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A16R_13130	COG2382	esterase
A16R_13160	COG5492	domain, Protein
A16R_13170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A16R_13200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A16R_13200	COG0512	Glutamine amidotransferase of anthranilate synthase
A16R_13280	COG1620	l-lactate permease
A16R_13290	COG5634	Uncharacterized conserved protein (DUF2278)
A16R_13390	COG0508	dehydrogenase complex catalyzes the overall conversion of
A16R_13410	COG1476	TRANSCRIPTIONal
A16R_13510	COG2226	methyltransferase
A16R_13530	COG1686	Belongs to the peptidase S11 family
A16R_13540	COG0681	Belongs to the peptidase S26 family
A16R_13610	COG1012	belongs to the aldehyde dehydrogenase family
A16R_13620	COG3842	ATPase activity
A16R_13630	COG1176	ABC-type spermidine putrescine transport system, permease component I
A16R_13640	COG1177	transmembrane transport
A16R_13650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A16R_13670	COG2409	Drug exporters of the RND superfamily
A16R_13690	COG0564	pseudouridine synthase activity
A16R_13710	COG2340	Cysteine-rich secretory protein family
A16R_13720	COG0247	lactate metabolic process
A16R_13730	COG0277	FAD linked oxidase domain protein
A16R_13740	COG3835	regulator
A16R_13760	COG0745	RESPONSE REGULATOR receiver
A16R_13770	COG5002	protein histidine kinase activity
A16R_13780	COG2186	Transcriptional regulator
A16R_13820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A16R_13850	COG2116	formate transmembrane transporter activity
A16R_13860	COG0861	Integral membrane protein TerC family
A16R_13870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A16R_13890	COG2030	dehydratase
A16R_13930	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_13940	COG3243	poly(R)-hydroxyalkanoic acid synthase
A16R_13960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A16R_13990	COG1840	ABC-type Fe3 transport system, periplasmic component
A16R_14030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A16R_14060	COG1349	DNA-binding transcription factor activity
A16R_14140	COG2861	carbohydrate metabolic process
A16R_14160	COG3852	Histidine kinase
A16R_14170	COG1846	Transcriptional regulator
A16R_14190	COG2318	DinB family
A16R_14210	COG5002	protein histidine kinase activity
A16R_14230	COG0720	synthase
A16R_14260	COG4873	Protein conserved in bacteria
A16R_14320	COG1780	Probably involved in ribonucleotide reductase function
A16R_14360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A16R_14370	COG1725	Transcriptional regulator
A16R_14380	COG1131	(ABC) transporter
A16R_14400	COG1131	(ABC) transporter
A16R_14410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A16R_14440	COG1522	sequence-specific DNA binding
A16R_14460	COG1335	isochorismatase
A16R_14480	COG1619	proteins homologs of microcin C7 resistance protein MccF
A16R_14490	COG2070	2-Nitropropane dioxygenase
A16R_14500	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A16R_14520	COG1696	Membrane protein involved in D-alanine export
A16R_14570	COG0716	FMN binding
A16R_14600	COG3173	Aminoglycoside phosphotransferase
A16R_14640	COG0534	Mate efflux family protein
A16R_14650	COG1968	undecaprenyl-diphosphatase activity
A16R_14680	COG1846	Transcriptional regulator
A16R_14700	COG1301	dicarboxylic acid transport
A16R_14710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A16R_14720	COG4709	membrane
A16R_14730	COG3874	Sporulation protein YtfJ
A16R_14780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A16R_14790	COG0028	Belongs to the TPP enzyme family
A16R_14800	COG0440	acetolactate synthase activity
A16R_14810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A16R_14830	COG0473	3-isopropylmalate dehydrogenase activity
A16R_14880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A16R_14950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A16R_14980	COG1183	phosphatidylcholine synthase activity
A16R_14990	COG1368	sulfuric ester hydrolase activity
A16R_15010	COG0019	diaminopimelate decarboxylase activity
A16R_15050	COG0529	Catalyzes the synthesis of activated sulfate
A16R_15060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A16R_15100	COG1648	precorrin-2 dehydrogenase activity
A16R_15110	COG0733	neurotransmitter:sodium symporter activity
A16R_15150	COG1757	Na H antiporter
A16R_15180	COG4758	membrane
A16R_15190	COG4585	Histidine kinase
A16R_15200	COG2197	response regulator
A16R_15220	COG1114	Component of the transport system for branched-chain amino acids
A16R_15230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A16R_15290	COG1017	nitric oxide dioxygenase activity
A16R_15290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A16R_15320	COG0730	response to heat
A16R_15330	COG0306	phosphate transporter
A16R_15340	COG1392	Phosphate transport regulator
A16R_15350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A16R_15390	COG3852	Histidine kinase
A16R_15400	COG1801	Protein of unknown function DUF72
A16R_15420	COG0582	viral genome integration into host DNA
A16R_15430	COG5002	protein histidine kinase activity
A16R_15470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A16R_15470	COG0392	lysyltransferase activity
A16R_15500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A16R_15510	COG1686	Belongs to the peptidase S11 family
A16R_15520	COG2715	membrane protein required for spore maturation
A16R_15530	COG0700	Nucleoside recognition
A16R_15540	COG1187	pseudouridine synthase activity
A16R_15560	COG1333	cytochrome c biogenesis protein
A16R_15570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A16R_15580	COG0745	RESPONSE REGULATOR receiver
A16R_15590	COG5002	protein histidine kinase activity
A16R_15600	COG2096	Adenosyltransferase
A16R_15630	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A16R_15640	COG1141	Ferredoxin
A16R_15650	COG4955	Helix-turn-helix domain
A16R_15660	COG0514	ATP-dependent DNA helicase (RecQ)
A16R_15670	COG1266	CAAX protease self-immunity
A16R_15720	COG4862	establishment of competence for transformation
A16R_15730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A16R_15770	COG0492	ferredoxin-NADP+ reductase activity
A16R_15780	COG0252	asparaginase activity
A16R_15910	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A16R_15940	COG0142	geranyltranstransferase activity
A16R_15960	COG0142	geranyltranstransferase activity
A16R_15970	COG0105	UTP biosynthetic process
A16R_16000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A16R_16010	COG0457	Tetratricopeptide repeat
A16R_16050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A16R_16070	COG4347	Protein of unknown function (DUF1405)
A16R_16130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_16140	COG1694	Mazg nucleotide pyrophosphohydrolase
A16R_16170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A16R_16180	COG0438	transferase activity, transferring glycosyl groups
A16R_16250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A16R_16250	COG1199	ATP-dependent helicase activity
A16R_16290	COG3935	DnaD domain protein
A16R_16300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A16R_16320	COG4499	WXG100 protein secretion system (Wss), protein YukC
A16R_16320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A16R_16410	COG4474	Belongs to the UPF0398 family
A16R_16430	COG0116	Belongs to the methyltransferase superfamily
A16R_16450	COG1199	ATP-dependent helicase activity
A16R_16460	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A16R_16480	COG3173	Aminoglycoside phosphotransferase
A16R_16490	COG0024	Methionine aminopeptidase
A16R_16520	COG2233	PERMEase
A16R_16530	COG2311	Membrane
A16R_16550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A16R_16570	COG0456	acetyltransferase
A16R_16620	COG0754	glutathionylspermidine amidase activity
A16R_16710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A16R_16740	COG1215	transferase activity, transferring glycosyl groups
A16R_16750	COG0438	transferase activity, transferring glycosyl groups
A16R_16780	COG0454	-acetyltransferase
A16R_16820	COG0328	RNA-DNA hybrid ribonuclease activity
A16R_16900	COG1280	lysine exporter protein (LysE YggA)
A16R_16930	COG3162	membrane
A16R_16940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A16R_16950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A16R_16970	COG0475	glutathione-regulated potassium exporter activity
A16R_17000	COG0789	Transcriptional regulator
A16R_17000	COG4978	Transcriptional regulator
A16R_17020	COG2323	membrane
A16R_17040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A16R_17150	COG1923	regulation of RNA biosynthetic process
A16R_17170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A16R_17180	COG1360	Flagellar Motor Protein
A16R_17190	COG2201	protein-glutamate methylesterase activity
A16R_17220	COG1776	CheC inhibitor of MCP methylation
A16R_17220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A16R_17250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A16R_17290	COG1256	bacterial-type flagellum assembly
A16R_17300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A16R_17350	COG1815	bacterial-type flagellum-dependent cell motility
A16R_17360	COG1558	bacterial-type flagellum-dependent cell motility
A16R_17370	COG1677	Flagellar hook-basal body complex protein FliE
A16R_17380	COG1766	The M ring may be actively involved in energy transduction
A16R_17400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A16R_17420	COG1157	protein secretion by the type III secretion system
A16R_17550	COG0463	Glycosyl transferase, family 2
A16R_17620	COG0457	Tetratricopeptide repeat
A16R_17620	COG0463	Glycosyl transferase, family 2
A16R_17670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A16R_17680	COG0741	lytic transglycosylase activity
A16R_17720	COG1776	CheC inhibitor of MCP methylation
A16R_17720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A16R_17740	COG1338	Plays a role in the flagellum-specific transport system
A16R_17750	COG1987	bacterial-type flagellum assembly
A16R_17770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A16R_17780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A16R_17810	COG4786	Flagellar basal body rod
A16R_17820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A16R_17870	COG1309	transcriptional regulator
A16R_17900	COG2329	Antibiotic biosynthesis monooxygenase
A16R_17960	COG3842	ATPase activity
A16R_17970	COG0725	ABC transporter, periplasmic molybdate-binding protein
A16R_17980	COG1177	transmembrane transport
A16R_17990	COG1234	tRNA 3'-trailer cleavage
A16R_18040	COG1686	Belongs to the peptidase S11 family
A16R_18060	COG0406	alpha-ribazole phosphatase activity
A16R_18130	COG0367	asparagine synthase
A16R_18190	COG1802	Transcriptional regulator
A16R_18200	COG0697	spore germination
A16R_18210	COG0523	cobalamin synthesis protein
A16R_18220	COG0701	Predicted permease
A16R_18250	COG1216	Glycosyl transferase, family 2
A16R_18250	COG0438	transferase activity, transferring glycosyl groups
A16R_18260	COG1757	Na H antiporter
A16R_18270	COG0114	fumarate hydratase activity
A16R_18330	COG3340	Belongs to the peptidase S51 family
A16R_18370	COG0785	Cytochrome C biogenesis protein
A16R_18440	COG2733	membrane
A16R_18510	COG1131	(ABC) transporter
A16R_18540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A16R_18550	COG0528	UMP kinase activity
A16R_18570	COG1027	Aspartate ammonia-lyase
A16R_18580	COG0281	malic enzyme
A16R_18610	COG0784	Response regulator, receiver
A16R_18630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A16R_18740	COG1051	belongs to the nudix hydrolase family
A16R_18750	COG0860	N-Acetylmuramoyl-L-alanine amidase
A16R_18800	COG1966	Carbon starvation protein
A16R_18840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_18860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A16R_18900	COG2223	nitrite transmembrane transporter activity
A16R_18910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A16R_18940	COG2244	polysaccharide biosynthetic process
A16R_18950	COG0733	neurotransmitter:sodium symporter activity
A16R_18970	COG5566	PFAM Mor transcription activator
A16R_18980	COG2323	membrane
A16R_19020	COG2084	Dehydrogenase
A16R_19050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A16R_19070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A16R_19080	COG0028	Belongs to the TPP enzyme family
A16R_19090	COG0440	acetolactate synthase activity
A16R_19100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A16R_19120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A16R_19170	COG2814	Major facilitator Superfamily
A16R_19180	COG3384	dioxygenase
A16R_19200	COG3279	Response regulator of the LytR AlgR family
A16R_19210	COG0427	acetyl-CoA hydrolase
A16R_19260	COG4166	transmembrane transport
A16R_19320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_19370	COG1914	H( )-stimulated, divalent metal cation uptake system
A16R_19400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A16R_19490	COG2390	Transcriptional regulator
A16R_19510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_19520	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A16R_19550	COG4224	UPF0291 protein
A16R_19590	COG0006	proline dipeptidase activity
A16R_19600	COG2132	Multicopper oxidase
A16R_19670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A16R_19720	COG1276	copper resistance
A16R_19720	COG2372	response to copper ion
A16R_19730	COG4549	nuclear export factor GLE1
A16R_19750	COG0697	spore germination
A16R_19760	COG0583	DNA-binding transcription factor activity
A16R_19770	COG1959	2 iron, 2 sulfur cluster binding
A16R_19780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A16R_19790	COG0778	Nitroreductase
A16R_19820	COG0628	permease
A16R_19830	COG0039	L-malate dehydrogenase activity
A16R_19840	COG1231	oxidoreductase activity
A16R_19850	COG0523	cobalamin synthesis protein
A16R_19900	COG2030	dehydratase
A16R_19910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_19930	COG0411	ABC transporter
A16R_19970	COG0583	DNA-binding transcription factor activity
A16R_20010	COG1846	Transcriptional regulator
A16R_20030	COG1271	oxidase subunit
A16R_20040	COG1294	oxidase, subunit
A16R_20050	COG4988	ABC transporter
A16R_20060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A16R_20100	COG1686	Belongs to the peptidase S11 family
A16R_20120	COG1388	LysM domain
A16R_20120	COG0791	NLP P60 protein
A16R_20140	COG1132	(ABC) transporter
A16R_20150	COG1132	(ABC) transporter
A16R_20160	COG0745	RESPONSE REGULATOR receiver
A16R_20170	COG5002	protein histidine kinase activity
A16R_20190	COG0300	oxidoreductase activity
A16R_20230	COG0726	polysaccharide deacetylase
A16R_20280	COG0460	homoserine dehydrogenase
A16R_20340	COG1316	TRANSCRIPTIONal
A16R_20360	COG0745	RESPONSE REGULATOR receiver
A16R_20370	COG5002	protein histidine kinase activity
A16R_20380	COG0726	polysaccharide deacetylase
A16R_20400	COG1285	pathogenesis
A16R_20410	COG1247	-acetyltransferase
A16R_20430	COG4264	IucA IucC family
A16R_20440	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_20480	COG1082	Xylose isomerase domain protein TIM barrel
A16R_20530	COG1279	arginine transmembrane transporter activity
A16R_20550	COG1752	Esterase of the alpha-beta hydrolase superfamily
A16R_20670	COG2002	toxin-antitoxin pair type II binding
A16R_20680	COG1404	Belongs to the peptidase S8 family
A16R_20690	COG0640	Transcriptional regulator
A16R_20700	COG0667	Aldo Keto reductase
A16R_20710	COG2814	Major facilitator Superfamily
A16R_20760	COG0840	transmembrane signaling receptor activity
A16R_20790	COG3949	Membrane
A16R_20800	COG0783	Belongs to the Dps family
A16R_20830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A16R_20850	COG1231	oxidoreductase activity
A16R_20870	COG4989	oxidoreductase activity
A16R_20880	COG0523	cobalamin synthesis protein
A16R_20890	COG0456	acetyltransferase
A16R_20980	COG0803	Belongs to the bacterial solute-binding protein 9 family
A16R_20980	COG3443	Belongs to the bacterial solute-binding protein 9 family
A16R_21000	COG0702	epimerase
A16R_21020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A16R_21040	COG4166	transmembrane transport
A16R_21070	COG0406	alpha-ribazole phosphatase activity
A16R_21090	COG5337	Spore coat protein CotH
A16R_21100	COG1051	belongs to the nudix hydrolase family
A16R_21110	COG0586	Pfam SNARE associated Golgi protein
A16R_21120	COG2244	polysaccharide biosynthetic process
A16R_21140	COG0701	Predicted permease
A16R_21150	COG3689	TIGRFAM TIGR03943 family protein
A16R_21160	COG1607	acyl-coa hydrolase
A16R_21170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A16R_21210	COG0702	epimerase
A16R_21220	COG2839	Protein conserved in bacteria
A16R_21230	COG1253	flavin adenine dinucleotide binding
A16R_21260	COG1114	Component of the transport system for branched-chain amino acids
A16R_21270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_21300	COG0860	N-Acetylmuramoyl-L-alanine amidase
A16R_21320	COG1876	peptidase activity
A16R_21340	COG0154	amidase activity
A16R_21350	COG2211	Major facilitator Superfamily
A16R_21390	COG0561	phosphatase activity
A16R_21410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A16R_21450	COG1819	glycosyl
A16R_21460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_21470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_21540	COG0456	acetyltransferase
A16R_21630	COG3874	Sporulation protein YtfJ
A16R_21680	COG2226	methyltransferase
A16R_21720	COG1082	Xylose isomerase domain protein TIM barrel
A16R_21730	COG0346	lactoylglutathione lyase activity
A16R_21750	COG0604	alcohol dehydrogenase
A16R_21760	COG1595	DNA-templated transcription, initiation
A16R_21820	COG0386	Belongs to the glutathione peroxidase family
A16R_21830	COG1305	Transglutaminase-like
A16R_21840	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A16R_21850	COG0714	Associated with various cellular activities
A16R_21880	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A16R_21890	COG1140	nitrate reductase beta subunit
A16R_21900	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A16R_21910	COG2181	nitrate reductase activity
A16R_21950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A16R_21960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A16R_21970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A16R_21980	COG0303	'Molybdopterin
A16R_21990	COG0314	molybdopterin synthase activity
A16R_22010	COG2223	nitrite transmembrane transporter activity
A16R_22040	COG1648	precorrin-2 dehydrogenase activity
A16R_22060	COG1587	Uroporphyrinogen-III synthase
A16R_22060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A16R_22070	COG2146	nitrite reductase [NAD(P)H] activity
A16R_22080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A16R_22090	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A16R_22170	COG2359	stage V sporulation protein S
A16R_22190	COG5632	N-Acetylmuramoyl-L-alanine amidase
A16R_22230	COG1418	mRNA catabolic process
A16R_22240	COG0488	(ABC) transporter
A16R_22270	COG0629	single-stranded DNA binding
A16R_22300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A16R_22310	COG1413	lyase activity
A16R_22340	COG2521	methyltransferase
A16R_22340	COG2136	Putative SAM-dependent methyltransferase
A16R_22350	COG0018	arginyl-trna synthetase
A16R_22410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A16R_22440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A16R_22450	COG0017	Asparaginyl-tRNA synthetase
A16R_22490	COG1674	ftsk spoiiie
A16R_22690	COG1929	Belongs to the glycerate kinase type-1 family
A16R_22720	COG0745	RESPONSE REGULATOR receiver
A16R_22730	COG3850	Histidine kinase
A16R_22730	COG5002	protein histidine kinase activity
A16R_22830	COG2610	gluconate transmembrane transporter activity
A16R_22840	COG1454	alcohol dehydrogenase
A16R_22850	COG1794	racemase activity, acting on amino acids and derivatives
A16R_22870	COG0456	acetyltransferase
A16R_22910	COG1131	(ABC) transporter
A16R_22920	COG4473	ABC transporter
A16R_22950	COG0546	phosphoglycolate phosphatase activity
A16R_22990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A16R_23020	COG0768	penicillin binding
A16R_23030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A16R_23040	COG0204	Acyl-transferase
A16R_23050	COG1272	protein, Hemolysin III
A16R_23070	COG0805	protein transport
A16R_23090	COG1307	EDD domain protein, DegV family
A16R_23100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A16R_23110	COG1999	signal sequence binding
A16R_23120	COG0071	Belongs to the small heat shock protein (HSP20) family
A16R_23130	COG0367	asparagine synthase
A16R_23170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_23180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A16R_23250	COG0668	transmembrane transport
A16R_23260	COG2203	Gaf domain
A16R_23260	COG4585	Histidine kinase
A16R_23270	COG2197	response regulator
A16R_23290	COG1737	Transcriptional regulator
A16R_23300	COG1064	alcohol dehydrogenase
A16R_23370	COG1070	Carbohydrate kinase
A16R_23440	COG1125	glycine betaine transport
A16R_23440	COG0517	IMP dehydrogenase activity
A16R_23450	COG1174	glycine betaine transport
A16R_23520	COG1253	flavin adenine dinucleotide binding
A16R_23530	COG1012	belongs to the aldehyde dehydrogenase family
A16R_23540	COG5506	Protein of unknown function (DUF1694)
A16R_23580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A16R_23590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A16R_23600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A16R_23610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A16R_23620	COG0456	acetyltransferase
A16R_23630	COG3829	transcription factor binding
A16R_23640	COG1509	lysine 2,3-aminomutase activity
A16R_23730	COG4326	sporulation control protein
A16R_23740	COG0671	phosphoesterase, PA-phosphatase related
A16R_23750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A16R_23980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A16R_24070	COG2814	Major facilitator Superfamily
A16R_24080	COG4841	protein insertion into membrane
A16R_24090	COG0372	Belongs to the citrate synthase family
A16R_24100	COG2079	MmgE PrpD family protein
A16R_24110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A16R_24130	COG1960	acyl-CoA dehydrogenase activity
A16R_24140	COG2084	Dehydrogenase
A16R_24150	COG1012	belongs to the aldehyde dehydrogenase family
A16R_24160	COG1280	lysine exporter protein (LysE YggA)
A16R_24170	COG1024	Enoyl-CoA hydratase
A16R_24200	COG0420	3'-5' exonuclease activity
A16R_24210	COG0419	ATPase involved in DNA repair
A16R_24270	COG2223	nitrite transmembrane transporter activity
A16R_24280	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_24290	COG1169	isochorismate synthase
A16R_24300	COG1021	2,3-dihydroxybenzoate-AMP ligase
A16R_24310	COG1535	isochorismatase
A16R_24310	COG3433	isochorismatase activity
A16R_24320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A16R_24330	COG3251	PFAM MbtH domain protein
A16R_24340	COG2814	Major facilitator Superfamily
A16R_24370	COG0776	regulation of translation
A16R_24390	COG2318	DinB family
A16R_24410	COG1115	amino acid carrier protein
A16R_24440	COG2329	Antibiotic biosynthesis monooxygenase
A16R_24450	COG1187	pseudouridine synthase activity
A16R_24470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A16R_24510	COG0596	Alpha beta hydrolase
A16R_24520	COG2814	Major facilitator Superfamily
A16R_24570	COG2226	methyltransferase
A16R_24650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_24720	COG1247	-acetyltransferase
A16R_24800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_24820	COG1278	Cold shock
A16R_24860	COG0010	Belongs to the arginase family
A16R_24870	COG0561	phosphatase activity
A16R_24940	COG0583	DNA-binding transcription factor activity
A16R_24950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A16R_24980	COG0583	DNA-binding transcription factor activity
A16R_24990	COG2258	MOSC domain
A16R_25030	COG1132	(ABC) transporter
A16R_25040	COG1132	(ABC) transporter
A16R_25070	COG1396	sequence-specific DNA binding
A16R_25130	COG1595	DNA-templated transcription, initiation
A16R_25200	COG1649	PFAM Uncharacterised BCR, COG1649
A16R_25250	COG2971	BadF BadG BcrA BcrD
A16R_25260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A16R_25270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A16R_25290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_25400	COG0577	efflux transmembrane transporter activity
A16R_25400	COG1136	(ABC) transporter
A16R_25410	COG3615	Tellurite resistance protein tehB
A16R_25410	COG0500	methyltransferase
A16R_25430	COG2226	methyltransferase
A16R_25440	COG3961	Belongs to the TPP enzyme family
A16R_25450	COG1846	Transcriptional regulator
A16R_25550	COG2195	Cleaves the N-terminal amino acid of tripeptides
A16R_25590	COG1595	DNA-templated transcription, initiation
A16R_25610	COG0768	penicillin binding
A16R_25660	COG2367	Beta-lactamase
A16R_25670	COG0671	phosphoesterase, PA-phosphatase related
A16R_25680	COG1609	Transcriptional regulator
A16R_25690	COG2814	Major facilitator Superfamily
A16R_25700	COG0673	inositol 2-dehydrogenase activity
A16R_25720	COG1012	belongs to the aldehyde dehydrogenase family
A16R_25780	COG3718	enzyme involved in inositol metabolism
A16R_25820	COG0737	Belongs to the 5'-nucleotidase family
A16R_25840	COG0737	Belongs to the 5'-nucleotidase family
A16R_25860	COG0457	Tetratricopeptide repeat
A16R_25870	COG1476	TRANSCRIPTIONal
A16R_25890	COG1876	peptidase activity
A16R_25940	COG1309	transcriptional regulator
A16R_25980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_26010	COG1252	NADH dehydrogenase
A16R_26020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_26050	COG1131	(ABC) transporter
A16R_26070	COG1309	transcriptional regulator
A16R_26100	COG1960	acyl-CoA dehydrogenase activity
A16R_26110	COG0439	Biotin carboxylase
A16R_26120	COG0511	ligase activity, forming carbon-carbon bonds
A16R_26130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A16R_26140	COG1024	Enoyl-CoA hydratase
A16R_26150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A16R_26160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A16R_26180	COG1247	-acetyltransferase
A16R_26190	COG0572	uridine kinase
A16R_26210	COG2318	DinB family
A16R_26220	COG1686	Belongs to the peptidase S11 family
A16R_26270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A16R_26380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A16R_26380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A16R_26410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A16R_26430	COG2814	Major facilitator Superfamily
A16R_26520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_26550	COG1063	alcohol dehydrogenase
A16R_26580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A16R_26590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A16R_26620	COG3773	Cell wall hydrolase
A16R_26640	COG0745	RESPONSE REGULATOR receiver
A16R_26720	COG1136	(ABC) transporter
A16R_26780	COG0460	homoserine dehydrogenase
A16R_26820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A16R_26990	COG2124	cytochrome p450
A16R_27060	COG0561	phosphatase activity
A16R_27080	COG5002	protein histidine kinase activity
A16R_27120	COG1819	glycosyl
A16R_27130	COG1794	racemase activity, acting on amino acids and derivatives
A16R_27150	COG1122	ATPase activity
A16R_27180	COG2205	protein histidine kinase activity
A16R_27210	COG0604	alcohol dehydrogenase
A16R_27250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A16R_27310	COG0693	protein deglycase activity
A16R_27360	COG2814	Major facilitator Superfamily
A16R_27390	COG0584	glycerophosphoryl diester phosphodiesterase
A16R_27440	COG0697	spore germination
A16R_27550	COG2816	NAD+ diphosphatase activity
A16R_27560	COG0592	DNA-directed DNA polymerase activity
A16R_27570	COG1051	belongs to the nudix hydrolase family
A16R_27640	COG3878	Protein conserved in bacteria
A16R_27740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A16R_27780	COG0322	excinuclease ABC activity
A16R_27870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A16R_27920	COG1011	Hydrolase
A16R_27970	COG0076	glutamate decarboxylase activity
A16R_28010	COG1523	belongs to the glycosyl hydrolase 13 family
A16R_28020	COG3227	Zinc metalloprotease (Elastase)
A16R_28070	COG0201	protein transport
A16R_28090	COG0697	spore germination
A16R_28180	COG4129	membrane
A16R_28230	COG2959	enzyme of heme biosynthesis
A16R_28240	COG3409	Peptidoglycan-binding domain 1 protein
A16R_28240	COG3773	Cell wall hydrolase
A16R_28270	COG3483	tryptophan 2,3-dioxygenase activity
A16R_28300	COG3844	kynureninase activity
A16R_28310	COG1309	transcriptional regulator
A16R_28370	COG3284	Transcriptional regulator
A16R_28410	COG1349	DNA-binding transcription factor activity
A16R_28450	COG1959	2 iron, 2 sulfur cluster binding
A16R_28490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A16R_28500	COG0508	dehydrogenase complex catalyzes the overall conversion of
A16R_28510	COG0022	dehydrogenase e1 component
A16R_28520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A16R_28550	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_28560	COG0456	acetyltransferase
A16R_28560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A16R_28610	COG4176	ABC-type proline glycine betaine transport system permease component
A16R_28620	COG0517	IMP dehydrogenase activity
A16R_28620	COG4175	Glycine betaine
A16R_28640	COG0740	serine-type endopeptidase activity
A16R_28670	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A16R_28680	COG2153	protein acetylation
A16R_28690	COG3397	chitin binding
A16R_28730	COG2205	protein histidine kinase activity
A16R_28790	COG2333	competence protein COMEC
A16R_28790	COG0658	competence protein
A16R_28900	COG3973	AAA domain
A16R_28930	COG2105	PFAM AIG2 family protein
A16R_28980	COG4637	Psort location Cytoplasmic, score
A16R_29030	COG3397	chitin binding
A16R_29050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A16R_29060	COG1115	amino acid carrier protein
A16R_29070	COG1012	belongs to the aldehyde dehydrogenase family
A16R_29080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A16R_29100	COG3938	Belongs to the proline racemase family
A16R_29110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A16R_29190	COG0586	Pfam SNARE associated Golgi protein
A16R_29220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A16R_29240	COG4166	transmembrane transport
A16R_29260	COG4948	Mandelate Racemase Muconate Lactonizing
A16R_29340	COG2936	dipeptidyl-peptidase activity
A16R_29350	COG5002	protein histidine kinase activity
A16R_29370	COG0745	RESPONSE REGULATOR receiver
A16R_29480	COG1307	EDD domain protein, DegV family
A16R_29520	COG2814	Major facilitator Superfamily
A16R_29540	COG1664	Polymer-forming cytoskeletal
A16R_29550	COG0789	Transcriptional regulator
A16R_29560	COG4533	DNA binding
A16R_29570	COG0477	Major facilitator Superfamily
A16R_29570	COG2814	Major facilitator Superfamily
A16R_29620	COG2261	transglycosylase associated protein
A16R_29650	COG2226	methyltransferase
A16R_29730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A16R_29740	COG5146	pantothenate kinase activity
A16R_29800	COG1131	(ABC) transporter
A16R_29880	COG0628	permease
A16R_29900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A16R_29910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A16R_29920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A16R_29930	COG1116	anion transmembrane transporter activity
A16R_30010	COG2746	aminoglycoside 3-N-acetyltransferase activity
A16R_30070	COG0697	spore germination
A16R_30080	COG2318	DinB family
A16R_30120	COG4912	Dna alkylation repair
A16R_30150	COG0726	polysaccharide deacetylase
A16R_30170	COG0861	Integral membrane protein TerC family
A16R_30180	COG1368	sulfuric ester hydrolase activity
A16R_30190	COG0488	(ABC) transporter
A16R_30210	COG2409	Drug exporters of the RND superfamily
A16R_30210	COG1033	growth of symbiont in host cell
A16R_30220	COG1033	growth of symbiont in host cell
A16R_30220	COG2409	Drug exporters of the RND superfamily
A16R_30230	COG1033	growth of symbiont in host cell
A16R_30230	COG2409	Drug exporters of the RND superfamily
A16R_30240	COG1309	transcriptional regulator
A16R_30290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A16R_30300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A16R_30310	COG1605	Chorismate mutase
A16R_30310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A16R_30390	COG3584	3D domain protein
A16R_30390	COG1388	LysM domain
A16R_30410	COG1595	DNA-templated transcription, initiation
A16R_30460	COG1879	ABC-type sugar transport system periplasmic component
A16R_30490	COG1172	Belongs to the binding-protein-dependent transport system permease family
A16R_30510	COG2390	Transcriptional regulator
A16R_30600	COG2329	Antibiotic biosynthesis monooxygenase
A16R_30640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_30660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A16R_30670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A16R_30700	COG1414	Transcriptional regulator
A16R_30710	COG0833	amino acid
A16R_30720	COG1690	Belongs to the RtcB family
A16R_30740	COG1785	Belongs to the alkaline phosphatase family
A16R_30760	COG3655	Transcriptional regulator
A16R_30790	COG4377	Putative membrane peptidase family (DUF2324)
A16R_30810	COG3279	Response regulator of the LytR AlgR family
A16R_30830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_30840	COG0346	lactoylglutathione lyase activity
A16R_30880	COG0714	Associated with various cellular activities
A16R_30970	COG0463	Glycosyl transferase, family 2
A16R_30990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A16R_31000	COG0753	catalase activity
A16R_31020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A16R_31080	COG0714	Associated with various cellular activities
A16R_31100	COG0778	Nitroreductase
A16R_31110	COG1846	Transcriptional regulator
A16R_31200	COG1725	Transcriptional regulator
A16R_31220	COG1136	(ABC) transporter
A16R_31220	COG0577	efflux transmembrane transporter activity
A16R_31270	COG2207	Transcriptional regulator
A16R_31280	COG0456	acetyltransferase
A16R_31320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_31360	COG0642	Histidine kinase
A16R_31370	COG0745	RESPONSE REGULATOR receiver
A16R_31380	COG0596	Alpha beta hydrolase
A16R_31440	COG0730	response to heat
A16R_31460	COG0833	amino acid
A16R_31480	COG4335	DNA alkylation repair
A16R_31590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A16R_31670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A16R_31680	COG1414	Transcriptional regulator
A16R_31710	COG0860	N-Acetylmuramoyl-L-alanine amidase
A16R_31720	COG0640	Transcriptional regulator
A16R_31740	COG1960	acyl-CoA dehydrogenase activity
A16R_31810	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A16R_31850	COG0574	Belongs to the PEP-utilizing enzyme family
A16R_31850	COG3848	Pyruvate phosphate dikinase
A16R_31870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_31900	COG5577	PFAM Coat F domain
A16R_31910	COG3403	YqcI/YcgG family
A16R_31920	COG1280	lysine exporter protein (LysE YggA)
A16R_32000	COG1063	alcohol dehydrogenase
A16R_32030	COG1027	Aspartate ammonia-lyase
A16R_32040	COG0252	asparaginase activity
A16R_32050	COG1396	sequence-specific DNA binding
A16R_32070	COG0322	excinuclease ABC activity
A16R_32080	COG0531	amino acid
A16R_32090	COG1114	Component of the transport system for branched-chain amino acids
A16R_32130	COG0281	malic enzyme
A16R_32180	COG0531	amino acid
A16R_32190	COG0697	spore germination
A16R_32220	COG0784	Response regulator, receiver
A16R_32250	COG2066	Belongs to the glutaminase family
A16R_32330	COG0737	Belongs to the 5'-nucleotidase family
A16R_32340	COG0753	catalase activity
A16R_32350	COG2267	carboxylic ester hydrolase activity
A16R_32360	COG1335	isochorismatase
A16R_32400	COG0583	DNA-binding transcription factor activity
A16R_32500	COG0415	Belongs to the DNA photolyase family
A16R_32510	COG0288	reversible hydration of carbon dioxide
A16R_32540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A16R_32550	COG5609	conserved protein (DUF2294)
A16R_32570	COG1575	Belongs to the MenA family. Type 1 subfamily
A16R_32580	COG2267	carboxylic ester hydrolase activity
A16R_32590	COG0803	Belongs to the bacterial solute-binding protein 9 family
A16R_32600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A16R_32610	COG1121	(ABC) transporter
A16R_32670	COG0798	PFAM Bile acid sodium symporter
A16R_32680	COG0346	lactoylglutathione lyase activity
A16R_32690	COG0640	Transcriptional regulator
A16R_32720	COG0443	Heat shock 70 kDa protein
A16R_32750	COG1522	sequence-specific DNA binding
A16R_32780	COG0346	lactoylglutathione lyase activity
A16R_32910	COG2814	Major facilitator Superfamily
A16R_32960	COG0745	RESPONSE REGULATOR receiver
A16R_32970	COG3850	Histidine kinase
A16R_32970	COG5002	protein histidine kinase activity
A16R_33020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A16R_33080	COG1476	TRANSCRIPTIONal
A16R_33110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_33120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A16R_33140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_33150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A16R_33180	COG1136	(ABC) transporter
A16R_33190	COG0577	efflux transmembrane transporter activity
A16R_33220	COG3850	Histidine kinase
A16R_33220	COG5002	protein histidine kinase activity
A16R_33240	COG2364	Membrane
A16R_33250	COG1846	Transcriptional regulator
A16R_33280	COG2808	Putative FMN-binding domain
A16R_33290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_33300	COG2271	Major facilitator Superfamily
A16R_33310	COG1556	Lactate utilization protein
A16R_33320	COG1139	Iron-sulfur cluster binding protein
A16R_33370	COG1619	proteins homologs of microcin C7 resistance protein MccF
A16R_33400	COG0738	Major facilitator superfamily
A16R_33410	COG0673	inositol 2-dehydrogenase activity
A16R_33420	COG0561	phosphatase activity
A16R_33450	COG1609	Transcriptional regulator
A16R_33460	COG0457	Tetratricopeptide repeat
A16R_33500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A16R_33570	COG0534	Mate efflux family protein
A16R_33610	COG2814	Major facilitator Superfamily
A16R_33620	COG1309	transcriptional regulator
A16R_33640	COG0814	amino acid
A16R_33650	COG1760	l-serine dehydratase
A16R_33660	COG1760	l-serine dehydratase
A16R_33680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A16R_33690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A16R_33710	COG1335	isochorismatase
A16R_33720	COG1522	sequence-specific DNA binding
A16R_33730	COG0531	amino acid
A16R_33760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A16R_33810	COG1595	DNA-templated transcription, initiation
A16R_33850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_33850	COG2207	Transcriptional regulator
A16R_33970	COG0477	Major facilitator Superfamily
A16R_33990	COG1846	Transcriptional regulator
A16R_34000	COG2814	Major facilitator Superfamily
A16R_34030	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A16R_34040	COG1131	(ABC) transporter
A16R_34090	COG2076	Multidrug Resistance protein
A16R_34100	COG1309	transcriptional regulator
A16R_34120	COG2031	fatty acid transporter
A16R_34140	COG2249	NAD(P)H dehydrogenase (quinone) activity
A16R_34200	COG1122	ATPase activity
A16R_34210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A16R_34260	COG1288	antiporter activity
A16R_34270	COG2356	endonuclease I
A16R_34300	COG3620	sequence-specific DNA binding
A16R_34310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A16R_34320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A16R_34330	COG0124	histidyl-tRNA synthetase
A16R_34360	COG1733	regulation of RNA biosynthetic process
A16R_34370	COG0778	Nitroreductase
A16R_34410	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_34430	COG1131	(ABC) transporter
A16R_34480	COG1011	Hydrolase
A16R_34550	COG0346	lactoylglutathione lyase activity
A16R_34560	COG1940	carbohydrate kinase activity
A16R_34590	COG0110	maltose O-acetyltransferase activity
A16R_34620	COG1136	(ABC) transporter
A16R_34640	COG0180	Tryptophanyl-tRNA synthetase
A16R_34650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A16R_34660	COG0628	permease
A16R_34700	COG2226	methyltransferase
A16R_34720	COG0477	Major facilitator Superfamily
A16R_34780	COG1253	flavin adenine dinucleotide binding
A16R_34790	COG0789	Transcriptional regulator
A16R_34800	COG0697	spore germination
A16R_34810	COG1357	PFAM Pentapeptide repeats (8 copies)
A16R_34820	COG3813	Protein conserved in bacteria
A16R_34830	COG2706	6-phosphogluconolactonase activity
A16R_34840	COG1070	Carbohydrate kinase
A16R_34860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A16R_34870	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A16R_34890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A16R_34900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A16R_34910	COG0604	alcohol dehydrogenase
A16R_34920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A16R_34950	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_35010	COG0656	L-ascorbic acid biosynthetic process
A16R_35020	COG2814	Major facilitator Superfamily
A16R_35050	COG0346	lactoylglutathione lyase activity
A16R_35060	COG0814	amino acid
A16R_35110	COG1393	Belongs to the ArsC family
A16R_35120	COG1733	regulation of RNA biosynthetic process
A16R_35130	COG2188	Transcriptional regulator
A16R_35160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A16R_35170	COG1733	regulation of RNA biosynthetic process
A16R_35180	COG1733	regulation of RNA biosynthetic process
A16R_35210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_35250	COG0384	phenazine biosynthesis protein PhzF
A16R_35270	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_35290	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_35320	COG1733	regulation of RNA biosynthetic process
A16R_35400	COG1191	sigma factor activity
A16R_35440	COG1309	transcriptional regulator
A16R_35530	COG1151	hydroxylamine reductase activity
A16R_35550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_35560	COG3409	Peptidoglycan-binding domain 1 protein
A16R_35560	COG3757	hydrolase, family 25
A16R_35630	COG2072	flavoprotein involved in K transport
A16R_35740	COG2814	Major facilitator Superfamily
A16R_35810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A16R_35820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A16R_35870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_35890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_35900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_35910	COG3739	integral membrane protein
A16R_35920	COG0384	phenazine biosynthesis protein PhzF
A16R_35980	COG0583	DNA-binding transcription factor activity
A16R_36020	COG1193	negative regulation of DNA recombination
A16R_36070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A16R_36080	COG1164	Oligoendopeptidase f
A16R_36090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A16R_36150	COG0584	glycerophosphoryl diester phosphodiesterase
A16R_36180	COG0640	Transcriptional regulator
A16R_36190	COG0604	alcohol dehydrogenase
A16R_36240	COG2808	Putative FMN-binding domain
A16R_36250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A16R_36270	COG0385	Bile acid
A16R_36280	COG0277	FAD linked oxidase domain protein
A16R_36340	COG1216	Glycosyl transferase, family 2
A16R_36350	COG1024	Enoyl-CoA hydratase
A16R_36380	COG1285	pathogenesis
A16R_36400	COG2514	catechol 2,3-dioxygenase activity
A16R_36410	COG2720	vancomycin resistance protein
A16R_36470	COG1278	Cold shock
A16R_36490	COG0716	FMN binding
A16R_36550	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_36570	COG0165	Argininosuccinate lyase
A16R_36600	COG4145	pantothenate transmembrane transporter activity
A16R_36620	COG1012	belongs to the aldehyde dehydrogenase family
A16R_36630	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_36650	COG1657	PFAM Prenyltransferase squalene oxidase
A16R_36670	COG2962	Rard protein
A16R_36680	COG3326	Membrane
A16R_36710	COG0489	protein tyrosine kinase activity
A16R_36730	COG0314	molybdopterin synthase activity
A16R_36740	COG0303	'Molybdopterin
A16R_36750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A16R_36760	COG2116	formate transmembrane transporter activity
A16R_36780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A16R_36790	COG5609	conserved protein (DUF2294)
A16R_36810	COG3383	formate dehydrogenase (NAD+) activity
A16R_36820	COG0697	spore germination
A16R_36910	COG2226	methyltransferase
A16R_36920	COG4166	transmembrane transport
A16R_36930	COG4166	transmembrane transport
A16R_36950	COG4166	transmembrane transport
A16R_36960	COG1301	dicarboxylic acid transport
A16R_36970	COG1316	TRANSCRIPTIONal
A16R_36990	COG1595	DNA-templated transcription, initiation
A16R_37040	COG1131	(ABC) transporter
A16R_37060	COG0673	inositol 2-dehydrogenase activity
A16R_37070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A16R_37080	COG0187	DNA topoisomerase II activity
A16R_37090	COG1832	CoA-binding protein
A16R_37100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A16R_37110	COG0745	RESPONSE REGULATOR receiver
A16R_37150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A16R_37160	COG4841	protein insertion into membrane
A16R_37170	COG0824	Thioesterase
A16R_37240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A16R_37250	COG2274	protein secretion by the type I secretion system
A16R_37260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A16R_37280	COG0726	polysaccharide deacetylase
A16R_37310	COG2211	Major facilitator Superfamily
A16R_37330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A16R_37350	COG0183	Belongs to the thiolase family
A16R_37360	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_37370	COG1268	BioY protein
A16R_37380	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_37470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_37490	COG5002	protein histidine kinase activity
A16R_37500	COG0400	carboxylic ester hydrolase activity
A16R_37510	COG0346	lactoylglutathione lyase activity
A16R_37520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A16R_37530	COG0069	glutamate synthase activity
A16R_37540	COG1902	pentaerythritol trinitrate reductase activity
A16R_37550	COG1329	Transcriptional regulator
A16R_37560	COG0010	Belongs to the arginase family
A16R_37610	COG2226	methyltransferase
A16R_37740	COG4846	Membrane protein involved in cytochrome C biogenesis
A16R_37750	COG0785	Cytochrome C biogenesis protein
A16R_37770	COG0583	DNA-binding transcription factor activity
A16R_37780	COG1380	Effector of murein hydrolase LrgA
A16R_37790	COG1346	cytolysis
A16R_37830	COG0730	response to heat
A16R_37910	COG1132	(ABC) transporter
A16R_37970	COG3639	organic phosphonate transmembrane transporter activity
A16R_37980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A16R_38010	COG0737	Belongs to the 5'-nucleotidase family
A16R_38030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A16R_38070	COG1695	Transcriptional regulator
A16R_38160	COG5632	N-Acetylmuramoyl-L-alanine amidase
A16R_38160	COG3409	Peptidoglycan-binding domain 1 protein
A16R_38160	COG1388	LysM domain
A16R_38170	COG4824	toxin secretion phage lysis holin
A16R_38590	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A16R_38760	COG1396	sequence-specific DNA binding
A16R_38810	COG0174	glutamine synthetase
A16R_38820	COG0789	Transcriptional regulator
A16R_38830	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A16R_38860	COG2860	membrane
A16R_38870	COG0464	growth
A16R_38930	COG3584	3D domain protein
A16R_38930	COG1388	LysM domain
A16R_38940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A16R_38940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A16R_38940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A16R_38950	COG1105	Belongs to the carbohydrate kinase PfkB family
A16R_38960	COG1349	DNA-binding transcription factor activity
A16R_39000	COG2322	membrane
A16R_39030	COG1113	amino acid transport
A16R_39060	COG1408	metallophosphoesterase
A16R_39070	COG2116	formate transmembrane transporter activity
A16R_39090	COG2217	Heavy metal translocating P-type atpase
A16R_39100	COG2608	mercury ion transmembrane transporter activity
A16R_39110	COG1937	Protein conserved in bacteria
A16R_39130	COG2819	hydrolase of the alpha beta superfamily
A16R_39140	COG1120	ATPase activity
A16R_39150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_39160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_39170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_39190	COG0708	Exodeoxyribonuclease III
A16R_39200	COG2169	Transcriptional regulator
A16R_39210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A16R_39220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A16R_39240	COG2364	Membrane
A16R_39280	COG2267	carboxylic ester hydrolase activity
A16R_39290	COG0346	lactoylglutathione lyase activity
A16R_39300	COG5001	Diguanylate cyclase
A16R_39300	COG3300	MHYT domain
A16R_39350	COG1346	cytolysis
A16R_39360	COG1380	Effector of murein hydrolase LrgA
A16R_39370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_39380	COG0508	dehydrogenase complex catalyzes the overall conversion of
A16R_39380	COG0596	Alpha beta hydrolase
A16R_39390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A16R_39430	COG1404	Belongs to the peptidase S8 family
A16R_39440	COG3773	Cell wall hydrolase
A16R_39450	COG0562	UDP-galactopyranose mutase
A16R_39460	COG1368	sulfuric ester hydrolase activity
A16R_39480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A16R_39500	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A16R_39590	COG4550	Control of competence regulator ComK, YlbF/YmcA
A16R_39600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A16R_39610	COG1013	pyruvate-flavodoxin oxidoreductase activity
A16R_39620	COG0674	pyruvate-flavodoxin oxidoreductase activity
A16R_39620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A16R_39640	COG2359	stage V sporulation protein S
A16R_39650	COG1692	metallophosphoesterase
A16R_39700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A16R_39710	COG1426	Protein conserved in bacteria
A16R_39740	COG0300	oxidoreductase activity
A16R_39750	COG0612	Peptidase, M16
A16R_39760	COG0612	Peptidase, M16
A16R_39830	COG2188	Transcriptional regulator
A16R_39840	COG1674	ftsk spoiiie
A16R_39860	COG0740	serine-type endopeptidase activity
A16R_39870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A16R_39890	COG0527	aspartate kinase activity
A16R_39900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A16R_39910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A16R_39920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A16R_39930	COG1873	PFAM PRC-barrel domain
A16R_39940	COG0612	Peptidase, M16
A16R_39950	COG0726	polysaccharide deacetylase
A16R_39980	COG0196	riboflavin kinase activity
A16R_40020	COG1550	Protein conserved in bacteria
A16R_40040	COG1358	cellular component organization or biogenesis
A16R_40060	COG0195	Participates in both transcription termination and antitermination
A16R_40100	COG0750	zinc metalloprotease
A16R_40110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A16R_40120	COG4589	Belongs to the CDS family
A16R_40130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A16R_40150	COG0528	UMP kinase activity
A16R_40210	COG4974	Belongs to the 'phage' integrase family
A16R_40260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A16R_40340	COG1837	Belongs to the UPF0109 family
A16R_40360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A16R_40380	COG0552	protein localization to endoplasmic reticulum
A16R_40430	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_40440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A16R_40480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A16R_40490	COG1461	Dihydroxyacetone kinase
A16R_40500	COG1302	Protein conserved in bacteria
A16R_40520	COG1564	THIamine pyrophosphokinase
A16R_40530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A16R_40560	COG0515	serine threonine protein kinase
A16R_40560	COG2815	serine threonine protein kinase
A16R_40570	COG0631	protein serine/threonine phosphatase activity
A16R_40590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A16R_40590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A16R_40620	COG0242	peptide deformylase activity
A16R_40630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A16R_40640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A16R_40660	COG0194	GDP metabolic process
A16R_40680	COG1561	YicC-like family, N-terminal region
A16R_40690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A16R_40710	COG0006	proline dipeptidase activity
A16R_40750	COG3069	C4-dicarboxylate transmembrane transporter activity
A16R_40830	COG0505	Belongs to the CarA family
A16R_40890	COG0564	pseudouridine synthase activity
A16R_40920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A16R_40930	COG3599	regulation of cell shape
A16R_40940	COG2302	S4 RNA-binding domain
A16R_40950	COG0762	integral membrane protein
A16R_40970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A16R_40990	COG1873	PFAM PRC-barrel domain
A16R_41000	COG1191	sigma factor activity
A16R_41010	COG1191	sigma factor activity
A16R_41030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A16R_41040	COG0849	cell division
A16R_41050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A16R_41060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A16R_41090	COG0772	Belongs to the SEDS family
A16R_41120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A16R_41130	COG0768	penicillin binding
A16R_41150	COG4839	cell division protein FtsL
A16R_41180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A16R_41220	COG1399	metal-binding, possibly nucleic acid-binding protein
A16R_41320	COG4824	toxin secretion phage lysis holin
A16R_41530	COG1802	Transcriptional regulator
A16R_41530	COG4626	Terminase
A16R_41580	COG0582	viral genome integration into host DNA
A16R_41730	COG1191	sigma factor activity
A16R_41770	COG1484	DNA-dependent DNA replication
A16R_41830	COG1396	sequence-specific DNA binding
A16R_41900	COG0582	viral genome integration into host DNA
A16R_41920	COG3480	Lon protease (S16) C-terminal proteolytic domain
A16R_41930	COG1752	Esterase of the alpha-beta hydrolase superfamily
A16R_41940	COG3314	Sporulation integral membrane protein YlbJ
A16R_41960	COG0742	ribosomal rna small subunit methyltransferase
A16R_42000	COG3679	Belongs to the UPF0342 family
A16R_42010	COG0406	alpha-ribazole phosphatase activity
A16R_42040	COG2340	Cysteine-rich secretory protein family
A16R_42070	COG3336	cytochrome c oxidase
A16R_42140	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A16R_42150	COG0772	Belongs to the SEDS family
A16R_42160	COG4838	Belongs to the UPF0358 family
A16R_42170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A16R_42180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A16R_42200	COG4896	Protein conserved in bacteria
A16R_42250	COG0483	inositol monophosphate 1-phosphatase activity
A16R_42290	COG1982	Orn Lys Arg decarboxylase major
A16R_42370	COG0508	dehydrogenase complex catalyzes the overall conversion of
A16R_42380	COG0022	dehydrogenase e1 component
A16R_42390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A16R_42410	COG0242	peptide deformylase activity
A16R_42420	COG0561	phosphatase activity
A16R_42440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A16R_42450	COG0569	domain protein
A16R_42490	COG0583	DNA-binding transcription factor activity
A16R_42520	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A16R_42540	COG4703	Protein of unknown function (DUF1797)
A16R_42580	COG2200	EAL domain
A16R_42590	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_42600	COG1408	metallophosphoesterase
A16R_42620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A16R_42710	COG2814	Major facilitator Superfamily
A16R_42760	COG3209	COG3209 Rhs family protein
A16R_42780	COG2205	protein histidine kinase activity
A16R_42800	COG0436	Aminotransferase
A16R_42820	COG1609	Transcriptional regulator
A16R_42840	COG3833	ABC-type maltose transport systems, permease component
A16R_42850	COG1175	transmembrane transport
A16R_42860	COG2182	Extracellular solute-binding protein
A16R_42880	COG0366	Alpha amylase catalytic
A16R_42890	COG3842	ATPase activity
A16R_42960	COG0183	Belongs to the thiolase family
A16R_43030	COG1695	Transcriptional regulator
A16R_43040	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_43080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A16R_43090	COG0436	Aminotransferase
A16R_43130	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A16R_43180	COG3706	GGDEF domain
A16R_43190	COG0778	Nitroreductase
A16R_43240	COG1263	PTS System
A16R_43240	COG2190	(PTS) system
A16R_43240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A16R_43250	COG3711	transcriptional antiterminator
A16R_43290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A16R_43330	COG1547	Domain of unknown function (DUF309)
A16R_43340	COG0456	acetyltransferase
A16R_43360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A16R_43370	COG4086	secreted protein
A16R_43380	COG0561	phosphatase activity
A16R_43390	COG0697	spore germination
A16R_43420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_43470	COG0733	neurotransmitter:sodium symporter activity
A16R_43510	COG1686	Belongs to the peptidase S11 family
A16R_43530	COG1131	(ABC) transporter
A16R_43560	COG1846	Transcriptional regulator
A16R_43590	COG0598	Magnesium transport protein CorA
A16R_43640	COG4974	Belongs to the 'phage' integrase family
A16R_43660	COG0735	belongs to the Fur family
A16R_43670	COG1300	Membrane
A16R_43710	COG0667	Aldo Keto reductase
A16R_43720	COG0656	L-ascorbic acid biosynthetic process
A16R_43730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A16R_43730	COG0456	acetyltransferase
A16R_43750	COG0737	Belongs to the 5'-nucleotidase family
A16R_43750	COG1525	nuclease
A16R_43750	COG4085	toxin activity
A16R_43780	COG0596	Alpha beta hydrolase
A16R_43790	COG2056	Na+-H+ antiporter family
A16R_43800	COG1609	Transcriptional regulator
A16R_43810	COG0456	acetyltransferase
A16R_43820	COG1073	alpha beta
A16R_43850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A16R_43850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A16R_43860	COG0307	riboflavin synthase, alpha
A16R_43900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A16R_43910	COG4106	trans-aconitate 2-methyltransferase activity
A16R_43920	COG1073	alpha beta
A16R_43920	COG2226	methyltransferase
A16R_43930	COG0156	8-amino-7-oxononanoate synthase activity
A16R_43950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A16R_43990	COG0737	Belongs to the 5'-nucleotidase family
A16R_44010	COG1522	sequence-specific DNA binding
A16R_44050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A16R_44070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A16R_44100	COG0300	oxidoreductase activity
A16R_44110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_44130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A16R_44140	COG1760	l-serine dehydratase
A16R_44150	COG1760	l-serine dehydratase
A16R_44190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A16R_44200	COG2195	Cleaves the N-terminal amino acid of tripeptides
A16R_44210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_44230	COG1376	ErfK ybiS ycfS ynhG family protein
A16R_44240	COG4129	membrane
A16R_44250	COG1126	abc transporter atp-binding protein
A16R_44260	COG0765	amino acid transport
A16R_44270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A16R_44310	COG2816	NAD+ diphosphatase activity
A16R_44320	COG0772	Belongs to the SEDS family
A16R_44330	COG0508	dehydrogenase complex catalyzes the overall conversion of
A16R_44340	COG0022	dehydrogenase e1 component
A16R_44350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A16R_44360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A16R_44380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A16R_44390	COG0280	phosphate acetyltransferase
A16R_44420	COG0584	glycerophosphoryl diester phosphodiesterase
A16R_44430	COG3093	addiction module antidote protein HigA
A16R_44450	COG0745	RESPONSE REGULATOR receiver
A16R_44460	COG0750	zinc metalloprotease
A16R_44470	COG0497	DNA recombination
A16R_44490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A16R_44510	COG0142	geranyltranstransferase activity
A16R_44570	COG1302	Protein conserved in bacteria
A16R_44580	COG0439	Biotin carboxylase
A16R_44590	COG0511	ligase activity, forming carbon-carbon bonds
A16R_44670	COG3854	ATPases associated with a variety of cellular activities
A16R_44710	COG0006	proline dipeptidase activity
A16R_44740	COG3872	metal-dependent enzyme
A16R_44760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A16R_44820	COG0095	Lipoate-protein ligase
A16R_44830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_44840	COG1609	Transcriptional regulator
A16R_44860	COG2076	Multidrug Resistance protein
A16R_44870	COG2076	Multidrug Resistance protein
A16R_44950	COG1131	(ABC) transporter
A16R_44960	COG1725	Transcriptional regulator
A16R_45020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A16R_45140	COG4970	Tfp pilus assembly protein FimT
A16R_45160	COG1459	type II secretion system
A16R_45280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A16R_45290	COG1410	methionine synthase
A16R_45290	COG0646	methionine synthase
A16R_45300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A16R_45300	COG0646	methionine synthase
A16R_45310	COG0626	cystathionine gamma-synthase activity
A16R_45320	COG0626	cystathionine gamma-synthase activity
A16R_45360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_45380	COG1940	carbohydrate kinase activity
A16R_45390	COG4483	Protein conserved in bacteria
A16R_45400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A16R_45420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A16R_45430	COG0704	Plays a role in the regulation of phosphate uptake
A16R_45440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A16R_45450	COG0581	inorganic phosphate transmembrane transporter activity
A16R_45460	COG0573	inorganic phosphate transmembrane transporter activity
A16R_45470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A16R_45490	COG0477	Major facilitator Superfamily
A16R_45500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A16R_45550	COG0735	belongs to the Fur family
A16R_45560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A16R_45570	COG1121	(ABC) transporter
A16R_45590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_45660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A16R_45670	COG2384	SAM-dependent methyltransferase
A16R_45680	COG2010	Cytochrome c
A16R_45690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A16R_45760	COG0517	IMP dehydrogenase activity
A16R_45790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A16R_45800	COG0295	cytidine deaminase activity
A16R_45810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A16R_45830	COG1480	7TM receptor with intracellular HD hydrolase
A16R_45840	COG1702	phosphate starvation-inducible protein PhoH
A16R_45870	COG1610	YqeY-like protein
A16R_45890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A16R_45900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A16R_45940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A16R_45960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A16R_45970	COG1733	regulation of RNA biosynthetic process
A16R_46020	COG1466	dna polymerase III delta subunit
A16R_46040	COG0658	competence protein
A16R_46040	COG2333	competence protein COMEC
A16R_46060	COG2131	deaminase
A16R_46070	COG1555	photosystem II stabilization
A16R_46070	COG1596	polysaccharide export
A16R_46080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A16R_46110	COG0799	negative regulation of ribosome biogenesis
A16R_46120	COG1713	HD superfamily hydrolase involved in NAD metabolism
A16R_46160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A16R_46170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A16R_46200	COG1191	sigma factor activity
A16R_46220	COG1595	DNA-templated transcription, initiation
A16R_46240	COG0778	Nitroreductase
A16R_46260	COG2357	RelA SpoT domain protein
A16R_46280	COG1785	Belongs to the alkaline phosphatase family
A16R_46300	COG2267	carboxylic ester hydrolase activity
A16R_46380	COG1404	Belongs to the peptidase S8 family
A16R_46400	COG3186	Phenylalanine-4-hydroxylase
A16R_46420	COG2514	catechol 2,3-dioxygenase activity
A16R_46430	COG2514	catechol 2,3-dioxygenase activity
A16R_46440	COG2259	Doxx family
A16R_46530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_46550	COG1454	alcohol dehydrogenase
A16R_46550	COG1012	belongs to the aldehyde dehydrogenase family
A16R_46640	COG0768	penicillin binding
A16R_46700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A16R_46740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A16R_46760	COG0628	permease
A16R_46800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A16R_46820	COG0482	sulfurtransferase activity
A16R_46830	COG1104	cysteine desulfurase activity
A16R_46840	COG1959	2 iron, 2 sulfur cluster binding
A16R_46860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A16R_46880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A16R_46900	COG0124	histidyl-tRNA synthetase
A16R_46930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A16R_46950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A16R_46950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A16R_46960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A16R_46970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A16R_46970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A16R_46990	COG2244	polysaccharide biosynthetic process
A16R_47000	COG2323	membrane
A16R_47020	COG1862	Preprotein translocase
A16R_47080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A16R_47100	COG0697	spore germination
A16R_47110	COG0697	spore germination
A16R_47120	COG0640	Transcriptional regulator
A16R_47180	COG0157	Belongs to the NadC ModD family
A16R_47190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A16R_47220	COG1827	regulation of RNA biosynthetic process
A16R_47230	COG2258	MOSC domain
A16R_47240	COG0077	Prephenate dehydratase
A16R_47250	COG0577	efflux transmembrane transporter activity
A16R_47260	COG0577	efflux transmembrane transporter activity
A16R_47270	COG1136	(ABC) transporter
A16R_47280	COG5002	protein histidine kinase activity
A16R_47300	COG0745	RESPONSE REGULATOR receiver
A16R_47310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A16R_47320	COG3290	protein histidine kinase activity
A16R_47340	COG2868	ribosomal protein
A16R_47360	COG1530	ribonuclease E activity
A16R_47370	COG1994	Peptidase M50
A16R_47380	COG0739	heme binding
A16R_47390	COG2894	cell division
A16R_47420	COG1792	Involved in formation and maintenance of cell shape
A16R_47430	COG1077	Cell shape determining protein MreB Mrl
A16R_47470	COG0285	dihydrofolate synthase activity
A16R_47480	COG0525	valine-tRNA ligase activity
A16R_47500	COG1388	LysM domain
A16R_47520	COG0113	porphobilinogen synthase activity
A16R_47530	COG1587	Uroporphyrinogen-III synthase
A16R_47550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A16R_47570	COG1846	Transcriptional regulator
A16R_47580	COG1764	response to oxidative stress
A16R_47610	COG0470	DNA polymerase III
A16R_47610	COG1067	ATP-dependent peptidase activity
A16R_47710	COG0622	Phosphoesterase
A16R_47720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A16R_47750	COG5401	PFAM Sporulation and spore germination
A16R_47800	COG1309	transcriptional regulator
A16R_47830	COG2197	response regulator
A16R_47840	COG2233	PERMEase
A16R_47860	COG0402	S-adenosylhomocysteine deaminase activity
A16R_47870	COG0402	S-adenosylhomocysteine deaminase activity
A16R_47910	COG0444	Belongs to the ABC transporter superfamily
A16R_47920	COG4608	Belongs to the ABC transporter superfamily
A16R_47930	COG3275	phosphorelay sensor kinase activity
A16R_47940	COG3279	Response regulator of the LytR AlgR family
A16R_47970	COG1983	PspC domain protein
A16R_47980	COG1396	sequence-specific DNA binding
A16R_47990	COG0697	spore germination
A16R_48010	COG1959	2 iron, 2 sulfur cluster binding
A16R_48020	COG1668	transmembrane transport
A16R_48030	COG4152	abc transporter atp-binding protein
A16R_48040	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A16R_48070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A16R_48080	COG1876	peptidase activity
A16R_48090	COG0824	Thioesterase
A16R_48100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A16R_48130	COG2009	succinate dehydrogenase
A16R_48140	COG1719	4-vinyl reductase, 4VR
A16R_48160	COG3118	belongs to the thioredoxin family
A16R_48170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A16R_48180	COG2086	electron transfer activity
A16R_48190	COG1024	Enoyl-CoA hydratase
A16R_48200	COG1309	transcriptional regulator
A16R_48210	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_48320	COG1131	(ABC) transporter
A16R_48330	COG2205	protein histidine kinase activity
A16R_48340	COG0745	RESPONSE REGULATOR receiver
A16R_48360	COG4895	conserved protein (DUF2196)
A16R_48370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A16R_48420	COG4509	Sortase family
A16R_48430	COG1120	ATPase activity
A16R_48490	COG5386	Cell surface protein
A16R_48500	COG1114	Component of the transport system for branched-chain amino acids
A16R_48510	COG1187	pseudouridine synthase activity
A16R_48530	COG1796	DNA polymerase
A16R_48530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A16R_48540	COG1286	toxin biosynthetic process
A16R_48590	COG0017	Asparaginyl-tRNA synthetase
A16R_48600	COG0072	phenylalanine-tRNA ligase activity
A16R_48600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_48620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A16R_48640	COG1418	mRNA catabolic process
A16R_48690	COG2814	Major facilitator Superfamily
A16R_48700	COG1566	PFAM secretion protein HlyD family protein
A16R_48710	COG1309	transcriptional regulator
A16R_48720	COG1363	Peptidase, m42
A16R_48760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A16R_48770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A16R_48790	COG1484	DNA-dependent DNA replication
A16R_48800	COG3611	Membrane attachment protein
A16R_48820	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A16R_48840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A16R_48850	COG0237	dephospho-CoA kinase activity
A16R_48860	COG1971	Probably functions as a manganese efflux pump
A16R_48870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A16R_48880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A16R_48880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A16R_48890	COG5002	protein histidine kinase activity
A16R_48900	COG0745	RESPONSE REGULATOR receiver
A16R_48950	COG0538	isocitrate dehydrogenase activity
A16R_48960	COG0372	Belongs to the citrate synthase family
A16R_48980	COG0628	permease
A16R_49040	COG1725	Transcriptional regulator
A16R_49050	COG0281	malic enzyme
A16R_49060	COG0587	DNA-directed DNA polymerase activity
A16R_49090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A16R_49140	COG4109	DRTGG domain
A16R_49170	COG0006	proline dipeptidase activity
A16R_49240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_49250	COG0662	Cupin 2, conserved barrel domain protein
A16R_49270	COG1476	TRANSCRIPTIONal
A16R_49300	COG1028	Short-chain dehydrogenase reductase Sdr
A16R_49310	COG0589	response to stress
A16R_49400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_49440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A16R_49450	COG0827	DNA restriction-modification system
A16R_49460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A16R_49470	COG3874	Sporulation protein YtfJ
A16R_49490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A16R_49500	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A16R_49520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A16R_49550	COG1104	cysteine desulfurase activity
A16R_49580	COG0583	DNA-binding transcription factor activity
A16R_49590	COG0697	spore germination
A16R_49620	COG1956	GAF domain-containing protein
A16R_49630	COG0626	cystathionine gamma-synthase activity
A16R_49670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A16R_49690	COG1595	DNA-templated transcription, initiation
A16R_49710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A16R_49720	COG0454	-acetyltransferase
A16R_49730	COG0517	IMP dehydrogenase activity
A16R_49740	COG0123	including yeast histone deacetylase and acetoin utilization protein
A16R_49760	COG0745	RESPONSE REGULATOR receiver
A16R_49780	COG0666	response to abiotic stimulus
A16R_49850	COG1609	Transcriptional regulator
A16R_49860	COG4851	CamS sex pheromone cAM373 precursor
A16R_49870	COG3118	belongs to the thioredoxin family
A16R_49890	COG2309	aminopeptidase activity
A16R_49920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_49960	COG1674	ftsk spoiiie
A16R_49980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_49990	COG4848	Belongs to the UPF0354 family
A16R_50000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A16R_50010	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A16R_50020	COG1363	Peptidase, m42
A16R_50040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_50070	COG0510	thiamine kinase activity
A16R_50080	COG1523	belongs to the glycosyl hydrolase 13 family
A16R_50100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A16R_50110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A16R_50120	COG1349	DNA-binding transcription factor activity
A16R_50130	COG1187	pseudouridine synthase activity
A16R_50140	COG2244	polysaccharide biosynthetic process
A16R_50150	COG2081	HI0933 family
A16R_50170	COG2814	Major facilitator Superfamily
A16R_50190	COG3832	glyoxalase III activity
A16R_50230	COG1329	Transcriptional regulator
A16R_50250	COG4975	Glucose uptake
A16R_50280	COG0314	molybdopterin synthase activity
A16R_50290	COG1763	Mo-molybdopterin cofactor biosynthetic process
A16R_50300	COG0303	'Molybdopterin
A16R_50320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A16R_50390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A16R_50410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A16R_50520	COG2814	Major facilitator Superfamily
A16R_50550	COG0490	domain, Protein
A16R_50560	COG0582	viral genome integration into host DNA
A16R_50580	COG1136	(ABC) transporter
A16R_50620	COG1242	4 iron, 4 sulfur cluster binding
A16R_50630	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A16R_50640	COG1131	(ABC) transporter
A16R_50660	COG1794	racemase activity, acting on amino acids and derivatives
A16R_50710	COG2267	carboxylic ester hydrolase activity
A16R_50720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A16R_50730	COG0671	phosphoesterase, PA-phosphatase related
A16R_50740	COG0438	transferase activity, transferring glycosyl groups
A16R_50760	COG0521	Mo-molybdopterin cofactor biosynthetic process
A16R_50890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A16R_50900	COG5002	protein histidine kinase activity
A16R_50910	COG4191	Histidine kinase
A16R_50920	COG2267	carboxylic ester hydrolase activity
A16R_50970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A16R_50980	COG1116	anion transmembrane transporter activity
A16R_50990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A16R_51040	COG0494	nUDIX hydrolase
A16R_51090	COG0288	reversible hydration of carbon dioxide
A16R_51100	COG1271	oxidase subunit
A16R_51110	COG1294	oxidase, subunit
A16R_51150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_51200	COG1842	Phage shock protein A
A16R_51260	COG5002	protein histidine kinase activity
A16R_51270	COG0745	RESPONSE REGULATOR receiver
A16R_51330	COG1597	lipid kinase activity
A16R_51400	COG0586	Pfam SNARE associated Golgi protein
A16R_51420	COG0577	efflux transmembrane transporter activity
A16R_51430	COG1136	(ABC) transporter
A16R_51450	COG0745	RESPONSE REGULATOR receiver
A16R_51460	COG2205	protein histidine kinase activity
A16R_51470	COG0577	efflux transmembrane transporter activity
A16R_51500	COG0577	efflux transmembrane transporter activity
A16R_51510	COG1136	(ABC) transporter
A16R_51600	COG3964	amidohydrolase
A16R_51660	COG4948	Mandelate Racemase Muconate Lactonizing
A16R_51680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A16R_51690	COG0596	Alpha beta hydrolase
A16R_51700	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A16R_51710	COG1169	isochorismate synthase
A16R_51720	COG1575	Belongs to the MenA family. Type 1 subfamily
A16R_51730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A16R_51740	COG1278	Cold shock
A16R_51780	COG0058	SHG alpha-glucan phosphorylase activity
A16R_51790	COG0297	glycogen (starch) synthase activity
A16R_51800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A16R_51810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A16R_51830	COG0039	L-malate dehydrogenase activity
A16R_52020	COG0544	peptidyl-prolyl cis-trans isomerase activity
A16R_52090	COG1285	pathogenesis
A16R_52130	COG0166	Belongs to the GPI family
A16R_52140	COG2155	Conserved Protein
A16R_52150	COG1098	S1 RNA binding domain
A16R_52160	COG0436	Aminotransferase
A16R_52170	COG1522	sequence-specific DNA binding
A16R_52180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A16R_52190	COG2267	carboxylic ester hydrolase activity
A16R_52210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A16R_52250	COG5018	Exonuclease
A16R_52260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A16R_52300	COG0423	glycine-tRNA ligase activity
A16R_52310	COG2050	protein possibly involved in aromatic compounds catabolism
A16R_52330	COG1268	BioY protein
A16R_52350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A16R_52360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A16R_52390	COG3584	3D domain protein
A16R_52420	COG1252	NADH dehydrogenase
A16R_52450	COG3708	Transcriptional regulator
A16R_52480	COG1683	Conserved Protein
A16R_52520	COG0316	Belongs to the HesB IscA family
A16R_52550	COG1252	NADH dehydrogenase
A16R_52580	COG0390	transport system, permease component
A16R_52590	COG2824	Alkylphosphonate utilization operon protein PhnA
A16R_52670	COG4837	Protein of unknown function (DUF1462)
A16R_52680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A16R_52700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A16R_52710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A16R_52740	COG2249	NAD(P)H dehydrogenase (quinone) activity
A16R_52750	COG0647	UMP catabolic process
A16R_52770	COG2445	Protein of unknown function DUF86
A16R_52780	COG1494	fructose-1,6-bisphosphatase
A16R_52810	COG4470	Protein conserved in bacteria
A16R_52830	COG0789	Transcriptional regulator
A16R_52840	COG4377	Putative membrane peptidase family (DUF2324)
A16R_52890	COG0739	heme binding
A16R_52910	COG3377	Domain of unknown function (DUF1805)
A16R_52920	COG0737	Belongs to the 5'-nucleotidase family
A16R_52940	COG1695	Transcriptional regulator
A16R_52960	COG0719	Fe-S assembly protein
A16R_52970	COG0822	iron-sulfur transferase activity
A16R_52980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A16R_52990	COG0719	Fe-S assembly protein
A16R_53010	COG0396	ATPase activity
A16R_53020	COG1464	Belongs to the NlpA lipoprotein family
A16R_53030	COG1464	Belongs to the NlpA lipoprotein family
A16R_53040	COG2011	ABC-type metal ion transport system permease component
A16R_53050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A16R_53080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A16R_53090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A16R_53110	COG1393	Belongs to the ArsC family
A16R_53190	COG0039	L-malate dehydrogenase activity
A16R_53230	COG1309	transcriptional regulator
A16R_53240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A16R_53250	COG1960	acyl-CoA dehydrogenase activity
A16R_53270	COG0183	Belongs to the thiolase family
A16R_53280	COG1024	Enoyl-CoA hydratase
A16R_53280	COG1250	3-hydroxyacyl-CoA dehydrogenase
A16R_53300	COG1686	Belongs to the peptidase S11 family
A16R_53330	COG0011	TIGRFAM Protein of
A16R_53340	COG0840	transmembrane signaling receptor activity
A16R_53380	COG2814	Major facilitator Superfamily
A16R_53390	COG0531	amino acid
A16R_53410	COG0706	membrane insertase activity
A16R_53430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A16R_53500	COG0586	Pfam SNARE associated Golgi protein
A16R_53520	COG1376	ErfK ybiS ycfS ynhG family protein
A16R_53530	COG0745	RESPONSE REGULATOR receiver
A16R_53540	COG5002	protein histidine kinase activity
A16R_53560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A16R_53590	COG2151	metal-sulfur cluster biosynthetic enzyme
A16R_53600	COG3227	Zinc metalloprotease (Elastase)
A16R_53610	COG1741	Belongs to the pirin family
A16R_53640	COG0475	glutathione-regulated potassium exporter activity
A16R_53650	COG0490	domain, Protein
A16R_53660	COG1115	amino acid carrier protein
A16R_53670	COG0783	Belongs to the Dps family
A16R_53710	COG1611	Belongs to the LOG family
A16R_53740	COG2311	Membrane
A16R_53780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_53790	COG1115	amino acid carrier protein
A16R_53800	COG1115	amino acid carrier protein
A16R_53810	COG2910	NAD(P)H-binding
A16R_53860	COG0656	L-ascorbic acid biosynthetic process
A16R_53870	COG2814	Major facilitator Superfamily
A16R_53880	COG1733	regulation of RNA biosynthetic process
A16R_53900	COG1252	NADH dehydrogenase
A16R_53910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A16R_53920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A16R_53940	COG3290	protein histidine kinase activity
A16R_53940	COG0840	transmembrane signaling receptor activity
A16R_53960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A16R_53970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A16R_54000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A16R_54010	COG3223	Belongs to the PsiE family
A16R_54110	COG0557	exoribonuclease II activity
A16R_54120	COG1647	Serine aminopeptidase, S33
A16R_54130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A16R_54140	COG1346	cytolysis
A16R_54330	COG4695	Portal protein
A16R_54380	COG4974	Belongs to the 'phage' integrase family
A16R_54420	COG0149	triose-phosphate isomerase activity
A16R_54440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A16R_54470	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A16R_54520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A16R_54550	COG2323	membrane
A16R_54560	COG0740	serine-type endopeptidase activity
A16R_54570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A16R_54590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A16R_54610	COG1051	belongs to the nudix hydrolase family
A16R_54630	COG0492	ferredoxin-NADP+ reductase activity
A16R_54640	COG0457	Tetratricopeptide repeat
A16R_54650	COG0110	maltose O-acetyltransferase activity
A16R_54700	COG1950	PFAM Membrane protein of
A16R_54720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A16R_54730	COG0556	nucleotide-excision repair
A16R_54770	COG0789	Transcriptional regulator
A16R_54820	COG2855	membrane
A16R_54830	COG0583	DNA-binding transcription factor activity
A16R_54850	COG0655	NAD(P)H dehydrogenase (quinone) activity
A16R_54880	COG1132	(ABC) transporter
A16R_54890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A16R_54900	COG3409	Peptidoglycan-binding domain 1 protein
A16R_54900	COG0793	Belongs to the peptidase S41A family
A16R_54910	COG2177	Part of the ABC transporter FtsEX involved in
A16R_54920	COG2884	Cell division ATP-binding protein ftsE
A16R_54980	COG0653	protein targeting
A16R_54990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A16R_55010	COG1278	Cold shock
A16R_55020	COG1040	competence protein
A16R_55030	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A16R_55040	COG0791	NLP P60 protein
A16R_55040	COG1388	LysM domain
A16R_55050	COG1733	regulation of RNA biosynthetic process
A16R_55060	COG1307	EDD domain protein, DegV family
A16R_55070	COG1739	Uncharacterized protein family UPF0029
A16R_55080	COG1316	TRANSCRIPTIONal
A16R_55090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A16R_55100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A16R_55110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A16R_55130	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A16R_55130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A16R_55160	COG3394	polysaccharide catabolic process
A16R_55170	COG1486	melibiose metabolic process
A16R_55180	COG1447	Phosphotransferase system cellobiose-specific component IIA
A16R_55190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A16R_55210	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A16R_55220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A16R_55230	COG1447	Phosphotransferase system cellobiose-specific component IIA
A16R_55250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A16R_55260	COG1301	dicarboxylic acid transport
A16R_55280	COG0346	lactoylglutathione lyase activity
A16R_55290	COG1511	domain protein
A16R_55300	COG0583	DNA-binding transcription factor activity
A16R_55310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A16R_55360	COG1271	oxidase subunit
A16R_55370	COG1294	oxidase, subunit
A16R_55380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A16R_55400	COG1620	l-lactate permease
A16R_55420	COG2389	metal-binding protein
A16R_55440	COG1368	sulfuric ester hydrolase activity
A16R_55490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_55540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A16R_55550	COG1388	LysM domain
A16R_55550	COG3584	3D domain protein
A16R_55600	COG4715	Zinc finger, swim domain protein
A16R_55610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A16R_55670	COG1191	sigma factor activity
A16R_55690	COG0577	efflux transmembrane transporter activity
A16R_55700	COG1136	(ABC) transporter
A16R_55780	COG5002	protein histidine kinase activity
A16R_55790	COG0745	RESPONSE REGULATOR receiver
A16R_55800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A16R_55840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A16R_55850	COG1134	teichoic acid transport
A16R_55860	COG1682	transport, permease protein
A16R_55870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A16R_55990	COG0739	heme binding
A16R_56020	COG3279	Response regulator of the LytR AlgR family
A16R_56030	COG4555	ABC transporter
A16R_56040	COG2385	sporulation resulting in formation of a cellular spore
A16R_56050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A16R_56070	COG4836	Membrane
A16R_56080	COG1007	ATP synthesis coupled electron transport
A16R_56090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A16R_56100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A16R_56120	COG0839	Belongs to the complex I subunit 6 family
A16R_56150	COG0649	NAD binding
A16R_56160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A16R_56180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A16R_56190	COG3300	MHYT domain
A16R_56190	COG5001	Diguanylate cyclase
A16R_56300	COG0356	it plays a direct role in the translocation of protons across the membrane
A16R_56370	COG0698	ribose 5-phosphate isomerase
A16R_56390	COG2190	(PTS) system
A16R_56400	COG2259	Doxx family
A16R_56410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A16R_56450	COG0009	L-threonylcarbamoyladenylate synthase
A16R_56490	COG2890	protein-(glutamine-N5) methyltransferase activity
A16R_56500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A16R_56530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A16R_56540	COG1494	fructose-1,6-bisphosphatase
A16R_56590	COG4821	SIS domain
A16R_56610	COG3343	RNA polymerase activity
A16R_56630	COG1960	acyl-CoA dehydrogenase activity
A16R_56640	COG1960	acyl-CoA dehydrogenase activity
A16R_56650	COG1250	3-hydroxyacyl-CoA dehydrogenase
A16R_56660	COG0183	Belongs to the thiolase family
A16R_56670	COG2181	nitrate reductase activity
A16R_56670	COG0247	lactate metabolic process
A16R_56680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A16R_56700	COG5001	Diguanylate cyclase
A16R_56700	COG3300	MHYT domain
A16R_56740	COG2197	response regulator
A16R_56750	COG4585	Histidine kinase
A16R_56760	COG0842	Transport permease protein
A16R_56770	COG1131	(ABC) transporter
A16R_56780	COG0024	Methionine aminopeptidase
A16R_56850	COG2234	aminopeptidase activity
A16R_56900	COG0018	arginyl-trna synthetase
A16R_56910	COG4506	Protein conserved in bacteria
A16R_56920	COG1619	proteins homologs of microcin C7 resistance protein MccF
A16R_56960	COG0010	Belongs to the arginase family
A16R_56970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A16R_56980	COG2814	Major facilitator Superfamily
A16R_56990	COG0789	Transcriptional regulator
A16R_57010	COG0584	glycerophosphoryl diester phosphodiesterase
A16R_57020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A16R_57040	COG1994	Peptidase M50
A16R_57060	COG1078	dGTPase activity
A16R_57070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A16R_57080	COG1120	ATPase activity
A16R_57090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_57110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_57150	COG0095	Lipoate-protein ligase
A16R_57160	COG0280	phosphate acetyltransferase
A16R_57190	COG3773	Cell wall hydrolase
A16R_57210	COG2363	Small membrane protein
A16R_57250	COG2233	PERMEase
A16R_57260	COG0561	phosphatase activity
A16R_57270	COG2814	Major facilitator Superfamily
A16R_57290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A16R_57300	COG1131	(ABC) transporter
A16R_57310	COG2755	lipolytic protein G-D-S-L family
A16R_57320	COG1609	Transcriptional regulator
A16R_57340	COG0460	homoserine dehydrogenase
A16R_57380	COG1011	Hydrolase
A16R_57390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A16R_57410	COG2197	response regulator
A16R_57440	COG0351	phosphomethylpyrimidine kinase
A16R_57450	COG3706	GGDEF domain
A16R_57460	COG2879	small protein
A16R_57470	COG1966	Carbon starvation protein
A16R_57480	COG3279	Response regulator of the LytR AlgR family
A16R_57500	COG0477	Major facilitator Superfamily
A16R_57580	COG1607	acyl-coa hydrolase
A16R_57620	COG0488	(ABC) transporter
A16R_57670	COG0463	Glycosyl transferase, family 2
A16R_57680	COG1309	transcriptional regulator
A16R_57690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A16R_57700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A16R_57700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A16R_57720	COG0628	permease
A16R_57750	COG3279	Response regulator of the LytR AlgR family
A16R_57760	COG3275	phosphorelay sensor kinase activity
A16R_57770	COG2814	Major facilitator Superfamily
A16R_57780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A16R_57790	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A16R_57800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A16R_57840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A16R_57910	COG0516	GMP reductase activity
A16R_57920	COG1164	Oligoendopeptidase f
A16R_57960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A16R_57970	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A16R_57980	COG4853	Protein conserved in bacteria
A16R_57990	COG4863	YycH protein
A16R_58000	COG5002	protein histidine kinase activity
A16R_58010	COG0745	RESPONSE REGULATOR receiver
A16R_58070	COG0305	Participates in initiation and elongation during chromosome replication
A16R_58090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A16R_58100	COG4241	membrane
A16R_58120	COG0629	single-stranded DNA binding
A16R_58140	COG0012	GTP binding
A16R_58150	COG4481	Protein conserved in bacteria
A16R_58160	COG0668	transmembrane transport
A16R_58180	COG1475	DNA binding
A16R_58190	COG1192	Involved in chromosome partitioning
A16R_58230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A16R_58240	COG1847	R3H domain protein
A16R_58250	COG0706	membrane insertase activity
A16R_58280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A16R_58285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A16R_58330	COG0084	hydrolase, TatD family'
A16R_58360	COG2252	PERMEase
A16R_58370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A16R_58400	COG0488	(ABC) transporter
A16R_58415	COG1396	sequence-specific DNA binding
A16R_58435	COG0582	viral genome integration into host DNA
A16R_58465	COG0070	glutamate synthase
A16R_58465	COG0069	glutamate synthase activity
A16R_58465	COG0067	glutamate synthase
A16R_58470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A16R_58495	COG0346	lactoylglutathione lyase activity
A16R_58515	COG0833	amino acid
A16R_58525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A16R_58555	COG1388	LysM domain
A16R_58555	COG3584	3D domain protein
A16R_58585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A16R_58645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A16R_58685	COG0367	asparagine synthase
A16R_58690	COG0004	ammonium transporteR
A16R_58710	COG4166	transmembrane transport
A16R_58720	COG1164	Oligoendopeptidase f
A16R_58850	COG2738	Putative neutral zinc metallopeptidase
A16R_58860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A16R_58870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A16R_58945	COG4191	Histidine kinase
A16R_58980	COG1073	alpha beta
A16R_59015	COG0318	PFAM AMP-dependent synthetase and ligase
A16R_59170	COG0471	metal ion transport
A16R_59180	COG0733	neurotransmitter:sodium symporter activity
A16R_59220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A16R_59225	COG1787	Restriction endonuclease
A16R_59225	COG1715	Restriction endonuclease
A16R_59255	COG4499	WXG100 protein secretion system (Wss), protein YukC
A16R_59255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A16R_59335	COG1309	transcriptional regulator
A16R_59390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A16R_59420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_59455	COG2223	nitrite transmembrane transporter activity
A16R_59470	COG4667	esterase of the alpha-beta hydrolase superfamily
A16R_59495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A16R_59510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A16R_59540	COG0514	ATP-dependent DNA helicase (RecQ)
A16R_59565	COG0519	Catalyzes the synthesis of GMP from XMP
A16R_59595	COG0436	Aminotransferase
A16R_59625	COG0287	Prephenate dehydrogenase
A16R_59650	COG4187	Peptidase family M20/M25/M40
A16R_59655	COG3239	Fatty acid desaturase
A16R_59700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A16R_59730	COG2169	Transcriptional regulator
A16R_59765	COG0583	DNA-binding transcription factor activity
A16R_59795	COG0662	Cupin 2, conserved barrel domain protein
A16R_59810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A16R_59825	COG0738	Major facilitator superfamily
A16R_59875	COG3152	Membrane
A16R_59885	COG1113	amino acid transport
A16R_59910	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A16R_59915	COG2427	Protein of unknown function (DUF1641)
A16R_59965	COG5632	N-Acetylmuramoyl-L-alanine amidase
A16R_59965	COG3409	Peptidoglycan-binding domain 1 protein
A16R_59970	COG1132	(ABC) transporter
A16R_60005	COG1595	DNA-templated transcription, initiation
A16R_60040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A16R_60045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A16R_60050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A16R_60055	COG1196	nuclear chromosome segregation
A16R_60070	COG1162	GTPase activity
A16R_60135	COG1396	sequence-specific DNA binding
A16R_60155	COG0517	IMP dehydrogenase activity
A16R_60200	COG1725	Transcriptional regulator
A16R_60280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A16R_60310	COG0358	DNA primase activity
A16R_60320	COG2226	methyltransferase
A16R_60325	COG1534	Rna-binding protein
A16R_60345	COG0626	cystathionine gamma-synthase activity
A16R_60350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A16R_60360	COG1104	cysteine desulfurase activity
A16R_60375	COG1053	succinate dehydrogenase
A16R_60380	COG2318	DinB family
A16R_60400	COG5386	Cell surface protein
A16R_60420	COG3030	protein affecting phage T7 exclusion by the F plasmid
A16R_60470	COG0475	glutathione-regulated potassium exporter activity
A16R_60520	COG2207	Transcriptional regulator
A16R_60520	COG3708	Transcriptional regulator
A16R_60530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A16R_60585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A16R_60610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A16R_60620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A16R_60650	COG1609	Transcriptional regulator
A16R_60670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A16R_60675	COG1595	DNA-templated transcription, initiation
A16R_60680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A16R_60695	COG0840	transmembrane signaling receptor activity
A16R_60705	COG1272	protein, Hemolysin III
A16R_60760	COG3344	reverse transcriptase
A16R_60840	COG3344	reverse transcriptase
A16R_61050	COG4962	Type ii secretion system protein e
A16R_61185	COG2311	Membrane
A16R_61210	COG4196	transglutaminase domain protein
A16R_61215	COG0671	phosphoesterase, PA-phosphatase related
A16R_61240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A16R_61245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A16R_61260	COG2801	Transposase and inactivated derivatives
A16R_61415	COG2002	toxin-antitoxin pair type II binding
A16R_61425	COG4974	Belongs to the 'phage' integrase family
A16R_61465	COG2801	Transposase and inactivated derivatives
A16R_61485	COG3443	Belongs to the bacterial solute-binding protein 9 family
A16R_61495	COG4974	Belongs to the 'phage' integrase family
A16R_61520	COG0457	Tetratricopeptide repeat
A16R_61525	COG1923	regulation of RNA biosynthetic process