locus-tag	class	description
BA_0002	COG0592	DNA-directed DNA polymerase activity
BA_0003	COG2501	S4 domain
BA_0005	COG0187	DNA topoisomerase II activity
BA_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BA_0008	COG0516	GMP reductase activity
BA_0008	COG0517	IMP dehydrogenase activity
BA_0009	COG1686	Belongs to the peptidase S11 family
BA_0014	COG1428	Deoxynucleoside kinase
BA_0015	COG1428	Deoxynucleoside kinase
BA_0016	COG1335	isochorismatase
BA_0018	COG0590	tRNA wobble adenosine to inosine editing
BA_0019	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BA_0026	COG1982	Orn Lys Arg decarboxylase major
BA_0028	COG0470	DNA polymerase III
BA_0029	COG1774	PSP1 C-terminal conserved region
BA_0031	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BA_0033	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BA_0034	COG2002	toxin-antitoxin pair type II binding
BA_0036	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_0036	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_0037	COG0084	hydrolase, TatD family'
BA_0038	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BA_0041	COG4466	Protein conserved in bacteria
BA_0044	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA_0046	COG0251	oxidation-reduction process
BA_0049	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BA_0050	COG0193	aminoacyl-tRNA hydrolase activity
BA_0052	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA_0053	COG2002	toxin-antitoxin pair type II binding
BA_0054	COG2244	polysaccharide biosynthetic process
BA_0055	COG3956	TIGRFAM MazG family protein
BA_0056	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BA_0060	COG1098	S1 RNA binding domain
BA_0061	COG2208	phosphoserine phosphatase activity
BA_0062	COG0037	tRNA processing
BA_0064	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA_0067	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA_0068	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BA_0069	COG0512	Glutamine amidotransferase of anthranilate synthase
BA_0070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA_0071	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BA_0072	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BA_0073	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA_0074	COG1396	sequence-specific DNA binding
BA_0075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA_0078	COG3880	PFAM UvrB UvrC protein
BA_0080	COG0542	response to heat
BA_0081	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BA_0083	COG4956	integral membrane protein (PIN domain superfamily)
BA_0088	COG1045	serine acetyltransferase
BA_0091	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA_0092	COG3688	RNA-binding protein containing a PIN domain
BA_0094	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BA_0095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA_0096	COG0250	Participates in transcription elongation, termination and antitermination
BA_0101	COG2813	Specifically methylates the guanine in position
BA_0103	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BA_0104	COG1358	cellular component organization or biogenesis
BA_0125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BA_0130	COG0201	protein transport
BA_0132	COG0024	Methionine aminopeptidase
BA_0134	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BA_0140	COG1122	ATPase activity
BA_0141	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BA_0142	COG0101	tRNA pseudouridine synthase activity
BA_0146	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA_0147	COG0489	protein tyrosine kinase activity
BA_0149	COG2194	sulfuric ester hydrolase activity
BA_0150	COG0726	polysaccharide deacetylase
BA_0155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BA_0156	COG4856	YbbR-like protein
BA_0159	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA_0160	COG0596	Alpha beta hydrolase
BA_0164	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BA_0165	COG1506	peptidase
BA_0165	COG0823	Involved in the tonB-independent uptake of proteins
BA_0165	COG4946	Tricorn protease homolog
BA_0173	COG2011	ABC-type metal ion transport system permease component
BA_0174	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA_0175	COG1464	Belongs to the NlpA lipoprotein family
BA_0178	COG0277	FAD linked oxidase domain protein
BA_0179	COG2271	Major facilitator Superfamily
BA_0181	COG2814	Major facilitator Superfamily
BA_0185	COG0601	transmembrane transport
BA_0186	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA_0187	COG0444	Belongs to the ABC transporter superfamily
BA_0188	COG4608	Belongs to the ABC transporter superfamily
BA_0189	COG4166	transmembrane transport
BA_0191	COG2207	Transcriptional regulator
BA_0194	COG4166	transmembrane transport
BA_0195	COG4166	transmembrane transport
BA_0196	COG0656	L-ascorbic acid biosynthetic process
BA_0197	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA_0200	COG4975	Glucose uptake
BA_0202	COG4149	molybdate abc transporter
BA_0205	COG1910	domain protein
BA_0208	COG0583	DNA-binding transcription factor activity
BA_0210	COG0697	spore germination
BA_0213	COG0204	Acyl-transferase
BA_0216	COG1609	Transcriptional regulator
BA_0218	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_0222	COG0084	hydrolase, TatD family'
BA_0223	COG5298	Protein conserved in bacteria
BA_0228	COG0488	(ABC) transporter
BA_0231	COG0747	negative chemotaxis
BA_0232	COG0601	transmembrane transport
BA_0234	COG0444	Belongs to the ABC transporter superfamily
BA_0235	COG4608	Belongs to the ABC transporter superfamily
BA_0240	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BA_0241	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA_0244	COG2814	Major facilitator Superfamily
BA_0246	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA_0248	COG4294	response to UV
BA_0249	COG0705	Rhomboid family
BA_0249	COG0457	Tetratricopeptide repeat
BA_0251	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BA_0252	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA_0253	COG0864	Transcriptional regulator
BA_0254	COG2337	Toxic component of a toxin-antitoxin (TA) module
BA_0255	COG2183	response to ionizing radiation
BA_0258	COG0802	atpase or kinase
BA_0259	COG1214	PFAM Peptidase M22, glycoprotease
BA_0260	COG0456	acetyltransferase
BA_0261	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BA_0262	COG0488	(ABC) transporter
BA_0265	COG1266	CAAX protease self-immunity
BA_0270	COG2252	PERMEase
BA_0272	COG5002	protein histidine kinase activity
BA_0275	COG2226	methyltransferase
BA_0280	COG1215	transferase activity, transferring glycosyl groups
BA_0283	COG1968	undecaprenyl-diphosphatase activity
BA_0286	COG2205	protein histidine kinase activity
BA_0287	COG0745	RESPONSE REGULATOR receiver
BA_0288	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BA_0289	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BA_0290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BA_0292	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA_0295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BA_0297	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BA_0299	COG0151	Belongs to the GarS family
BA_0305	COG0210	DNA helicase
BA_0307	COG4851	CamS sex pheromone cAM373 precursor
BA_0311	COG1335	isochorismatase
BA_0312	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA_0313	COG2011	ABC-type metal ion transport system permease component
BA_0314	COG1464	Belongs to the NlpA lipoprotein family
BA_0318	COG1846	Transcriptional regulator
BA_0323	COG1597	lipid kinase activity
BA_0324	COG0546	phosphoglycolate phosphatase activity
BA_0325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA_0327	COG1012	belongs to the aldehyde dehydrogenase family
BA_0328	COG2076	Multidrug Resistance protein
BA_0329	COG2309	aminopeptidase activity
BA_0332	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_0333	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA_0334	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA_0336	COG4807	Protein conserved in bacteria
BA_0342	COG1473	amidohydrolase
BA_0345	COG0450	alkyl hydroperoxide reductase
BA_0346	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BA_0348	COG0235	Class ii aldolase
BA_0349	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_0350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_0351	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_0354	COG0166	Belongs to the GPI family
BA_0363	COG3541	Predicted nucleotidyltransferase
BA_0364	COG2814	Major facilitator Superfamily
BA_0365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA_0365	COG0723	plastoquinol--plastocyanin reductase activity
BA_0369	COG0840	transmembrane signaling receptor activity
BA_0370	COG0840	transmembrane signaling receptor activity
BA_0371	COG0366	Alpha amylase catalytic
BA_0372	COG2190	(PTS) system
BA_0372	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_0372	COG1263	PTS System
BA_0378	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BA_0381	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA_0383	COG1116	anion transmembrane transporter activity
BA_0384	COG0488	(ABC) transporter
BA_0393	COG2270	Major facilitator Superfamily
BA_0396	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA_0399	COG2310	stress, protein
BA_0400	COG2310	stress, protein
BA_0401	COG2310	stress, protein
BA_0402	COG0861	Integral membrane protein TerC family
BA_0404	COG3853	Toxic anion resistance protein (TelA)
BA_0407	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA_0409	COG1295	ribonuclease BN
BA_0410	COG2217	Heavy metal translocating P-type atpase
BA_0411	COG0697	spore germination
BA_0415	COG0586	Pfam SNARE associated Golgi protein
BA_0418	COG3871	stress protein (general stress protein 26)
BA_0419	COG0387	Pfam Sodium calcium exchanger
BA_0421	COG0535	radical SAM domain protein
BA_0426	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA_0427	COG0582	viral genome integration into host DNA
BA_0428	COG1396	sequence-specific DNA binding
BA_0432	COG1396	sequence-specific DNA binding
BA_0439	COG1484	DNA-dependent DNA replication
BA_0487	COG0101	tRNA pseudouridine synthase activity
BA_0489	COG3829	transcription factor binding
BA_0492	COG0833	amino acid
BA_0493	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA_0499	COG2066	Belongs to the glutaminase family
BA_0501	COG1263	PTS System
BA_0501	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_0502	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA_0505	COG0463	Glycosyl transferase, family 2
BA_0507	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA_0507	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BA_0510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BA_0514	COG1228	amidohydrolase
BA_0515	COG1090	epimerase
BA_0521	COG1988	membrane-bound metal-dependent
BA_0522	COG1194	a g-specific adenine glycosylase
BA_0528	COG1132	(ABC) transporter
BA_0529	COG4129	membrane
BA_0530	COG0070	glutamate synthase
BA_0530	COG0067	glutamate synthase
BA_0530	COG0069	glutamate synthase activity
BA_0532	COG4555	ABC transporter
BA_0536	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA_0537	COG0735	belongs to the Fur family
BA_0543	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BA_0544	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA_0545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BA_0547	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BA_0550	COG2766	serine protein kinase
BA_0554	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA_0556	COG1585	Membrane protein implicated in regulation of membrane protease activity
BA_0557	COG2268	Band 7 protein
BA_0559	COG3290	protein histidine kinase activity
BA_0561	COG2851	Citrate transporter
BA_0565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BA_0566	COG3842	ATPase activity
BA_0567	COG1175	transmembrane transport
BA_0568	COG0395	ABC-type sugar transport system, permease component
BA_0570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA_0571	COG0745	RESPONSE REGULATOR receiver
BA_0572	COG5002	protein histidine kinase activity
BA_0574	COG4990	cell redox homeostasis
BA_0576	COG3290	protein histidine kinase activity
BA_0577	COG4565	transcriptional regulatory protein
BA_0578	COG3493	citrate carrier protein
BA_0579	COG0281	malic enzyme
BA_0582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_0584	COG5002	protein histidine kinase activity
BA_0585	COG0745	RESPONSE REGULATOR receiver
BA_0587	COG0456	acetyltransferase
BA_0587	COG0454	-acetyltransferase
BA_0588	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA_0589	COG3383	formate dehydrogenase (NAD+) activity
BA_0593	COG0531	amino acid
BA_0594	COG0640	Transcriptional regulator
BA_0595	COG2217	Heavy metal translocating P-type atpase
BA_0596	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BA_0599	COG3227	Zinc metalloprotease (Elastase)
BA_0604	COG2720	vancomycin resistance protein
BA_0605	COG1316	TRANSCRIPTIONal
BA_0606	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_0607	COG0346	lactoylglutathione lyase activity
BA_0608	COG1253	flavin adenine dinucleotide binding
BA_0609	COG1027	Aspartate ammonia-lyase
BA_0610	COG1620	l-lactate permease
BA_0614	COG3104	oligopeptide transport
BA_0615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_0616	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_0617	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_0619	COG2226	methyltransferase
BA_0620	COG0156	8-amino-7-oxononanoate synthase activity
BA_0621	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA_0623	COG4548	von Willebrand factor, type A
BA_0624	COG0714	Associated with various cellular activities
BA_0625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA_0629	COG0531	amino acid
BA_0630	COG2188	Transcriptional regulator
BA_0631	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_0631	COG1263	PTS System
BA_0632	COG0366	Alpha amylase catalytic
BA_0635	COG0697	spore germination
BA_0637	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA_0638	COG1115	amino acid carrier protein
BA_0639	COG1126	abc transporter atp-binding protein
BA_0640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA_0641	COG0765	amino acid transport
BA_0642	COG0765	amino acid transport
BA_0643	COG0833	amino acid
BA_0648	COG2378	regulation of single-species biofilm formation
BA_0649	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BA_0650	COG5002	protein histidine kinase activity
BA_0653	COG0659	secondary active sulfate transmembrane transporter activity
BA_0656	COG0747	negative chemotaxis
BA_0658	COG0601	transmembrane transport
BA_0659	COG4608	Belongs to the ABC transporter superfamily
BA_0661	COG2271	Major facilitator Superfamily
BA_0662	COG1846	Transcriptional regulator
BA_0664	COG1609	Transcriptional regulator
BA_0665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA_0667	COG1129	ABC transporter
BA_0668	COG1172	Belongs to the binding-protein-dependent transport system permease family
BA_0669	COG1879	ABC-type sugar transport system periplasmic component
BA_0670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BA_0675	COG1063	alcohol dehydrogenase
BA_0678	COG3568	Endonuclease Exonuclease Phosphatase
BA_0683	COG1968	undecaprenyl-diphosphatase activity
BA_0684	COG0840	transmembrane signaling receptor activity
BA_0685	COG1388	LysM domain
BA_0685	COG3584	3D domain protein
BA_0686	COG1476	TRANSCRIPTIONal
BA_0689	COG3104	oligopeptide transport
BA_0690	COG1114	Component of the transport system for branched-chain amino acids
BA_0693	COG1113	amino acid transport
BA_0694	COG2252	PERMEase
BA_0699	COG0475	glutathione-regulated potassium exporter activity
BA_0699	COG0569	domain protein
BA_0702	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BA_0703	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BA_0704	COG0833	amino acid
BA_0705	COG4990	cell redox homeostasis
BA_0708	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA_0709	COG0697	spore germination
BA_0710	COG0531	amino acid
BA_0714	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BA_0714	COG1918	ferrous iron import across plasma membrane
BA_0715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BA_0716	COG0573	inorganic phosphate transmembrane transporter activity
BA_0717	COG0581	inorganic phosphate transmembrane transporter activity
BA_0719	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA_0720	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BA_0725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BA_0726	COG1116	anion transmembrane transporter activity
BA_0727	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA_0728	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA_0729	COG0352	thiamine-phosphate diphosphorylase activity
BA_0730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA_0731	COG2104	thiamine diphosphate biosynthetic process
BA_0733	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA_0734	COG0351	phosphomethylpyrimidine kinase
BA_0742	COG2205	protein histidine kinase activity
BA_0743	COG2814	Major facilitator Superfamily
BA_0744	COG1846	Transcriptional regulator
BA_0747	COG2252	PERMEase
BA_0748	COG1028	Short-chain dehydrogenase reductase Sdr
BA_0752	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA_0753	COG1621	beta-fructofuranosidase activity
BA_0754	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_0754	COG1263	PTS System
BA_0755	COG1609	Transcriptional regulator
BA_0757	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA_0758	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BA_0766	COG0778	Nitroreductase
BA_0767	COG2719	SpoVR family
BA_0774	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA_0775	COG1937	Protein conserved in bacteria
BA_0776	COG0425	Belongs to the sulfur carrier protein TusA family
BA_0776	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_0777	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_0777	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_0778	COG0425	Belongs to the sulfur carrier protein TusA family
BA_0779	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_0781	COG0730	response to heat
BA_0783	COG1316	TRANSCRIPTIONal
BA_0784	COG0604	alcohol dehydrogenase
BA_0785	COG1283	sodium-dependent phosphate transmembrane transporter activity
BA_0790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA_0790	COG3711	transcriptional antiterminator
BA_0791	COG1447	Phosphotransferase system cellobiose-specific component IIA
BA_0792	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BA_0796	COG3584	3D domain protein
BA_0796	COG1388	LysM domain
BA_0797	COG0577	efflux transmembrane transporter activity
BA_0798	COG1136	(ABC) transporter
BA_0800	COG5522	Integral membrane protein (intg_mem_TP0381)
BA_0802	COG1114	Component of the transport system for branched-chain amino acids
BA_0803	COG3546	catalase activity
BA_0810	COG0586	Pfam SNARE associated Golgi protein
BA_0818	COG0531	amino acid
BA_0819	COG0475	glutathione-regulated potassium exporter activity
BA_0821	COG1737	Transcriptional regulator
BA_0823	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_0823	COG1263	PTS System
BA_0825	COG2259	Doxx family
BA_0829	COG0697	spore germination
BA_0830	COG1522	sequence-specific DNA binding
BA_0832	COG2076	Multidrug Resistance protein
BA_0833	COG2076	Multidrug Resistance protein
BA_0834	COG1309	transcriptional regulator
BA_0835	COG2814	Major facilitator Superfamily
BA_0836	COG1733	regulation of RNA biosynthetic process
BA_0838	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA_0839	COG4533	DNA binding
BA_0840	COG2211	Major facilitator Superfamily
BA_0842	COG0693	protein deglycase activity
BA_0843	COG0753	catalase activity
BA_0843	COG0693	protein deglycase activity
BA_0845	COG0531	amino acid
BA_0847	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BA_0849	COG1012	belongs to the aldehyde dehydrogenase family
BA_0852	COG1132	(ABC) transporter
BA_0855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA_0856	COG0765	amino acid transport
BA_0857	COG1126	abc transporter atp-binding protein
BA_0860	COG0189	ligase activity
BA_0866	COG0028	Belongs to the TPP enzyme family
BA_0867	COG3527	Alpha-acetolactate decarboxylase
BA_0870	COG0561	phosphatase activity
BA_0872	COG5632	N-Acetylmuramoyl-L-alanine amidase
BA_0872	COG3409	Peptidoglycan-binding domain 1 protein
BA_0875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA_0878	COG0659	secondary active sulfate transmembrane transporter activity
BA_0882	COG0653	protein targeting
BA_0883	COG2244	polysaccharide biosynthetic process
BA_0885	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA_0887	COG4196	transglutaminase domain protein
BA_0890	COG1696	Membrane protein involved in D-alanine export
BA_0894	COG1024	Enoyl-CoA hydratase
BA_0897	COG1363	Peptidase, m42
BA_0901	COG3938	Belongs to the proline racemase family
BA_0909	COG0601	transmembrane transport
BA_0910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA_0912	COG4608	Belongs to the ABC transporter superfamily
BA_0921	COG0477	Major facilitator Superfamily
BA_0923	COG3290	protein histidine kinase activity
BA_0924	COG4565	transcriptional regulatory protein
BA_0925	COG3181	Tripartite tricarboxylate transporter family receptor
BA_0931	COG4978	Transcriptional regulator
BA_0931	COG0789	Transcriptional regulator
BA_0934	COG0305	Participates in initiation and elongation during chromosome replication
BA_0944	COG0477	Major facilitator Superfamily
BA_0954	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BA_0954	COG3320	Male sterility
BA_0959	COG1183	phosphatidylcholine synthase activity
BA_0963	COG2376	Dihydroxyacetone kinase
BA_0965	COG2376	Dihydroxyacetone kinase
BA_0966	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA_0967	COG1959	2 iron, 2 sulfur cluster binding
BA_0975	COG3437	response regulator, receiver
BA_0975	COG2770	Histidine kinase
BA_0987	COG3237	CsbD-like
BA_0992	COG1191	sigma factor activity
BA_0994	COG2208	phosphoserine phosphatase activity
BA_0995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BA_0996	COG0784	Response regulator, receiver
BA_0996	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA_0996	COG2198	Histidine kinase
BA_0996	COG2205	protein histidine kinase activity
BA_1001	COG0393	Putative heavy-metal-binding
BA_1008	COG0420	3'-5' exonuclease activity
BA_1009	COG4717	serine-type aminopeptidase activity
BA_1013	COG1309	transcriptional regulator
BA_1014	COG2814	Major facilitator Superfamily
BA_1015	COG0346	lactoylglutathione lyase activity
BA_1016	COG0346	lactoylglutathione lyase activity
BA_1017	COG0457	Tetratricopeptide repeat
BA_1019	COG2267	carboxylic ester hydrolase activity
BA_1024	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BA_1025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BA_1027	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BA_1037	COG0477	Major facilitator Superfamily
BA_1038	COG0477	Major facilitator Superfamily
BA_1040	COG3973	AAA domain
BA_1041	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA_1046	COG4980	gas vesicle protein
BA_1047	COG0537	adenosine 5'-monophosphoramidase activity
BA_1048	COG1131	(ABC) transporter
BA_1049	COG4473	ABC transporter
BA_1052	COG1309	transcriptional regulator
BA_1054	COG3402	PFAM membrane-flanked domain
BA_1065	COG3402	PFAM membrane-flanked domain
BA_1066	COG3428	Bacterial PH domain
BA_1068	COG2329	Antibiotic biosynthesis monooxygenase
BA_1069	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA_1070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BA_1080	COG1309	transcriptional regulator
BA_1081	COG1511	domain protein
BA_1086	COG1609	Transcriptional regulator
BA_1088	COG1234	tRNA 3'-trailer cleavage
BA_1089	COG0095	Lipoate-protein ligase
BA_1091	COG0318	PFAM AMP-dependent synthetase and ligase
BA_1098	COG3209	COG3209 Rhs family protein
BA_1111	COG1078	dGTPase activity
BA_1113	COG1595	DNA-templated transcription, initiation
BA_1114	COG2207	Transcriptional regulator
BA_1114	COG3708	Transcriptional regulator
BA_1118	COG2205	protein histidine kinase activity
BA_1119	COG0745	RESPONSE REGULATOR receiver
BA_1124	COG0501	Belongs to the peptidase M48B family
BA_1125	COG0840	transmembrane signaling receptor activity
BA_1126	COG0697	spore germination
BA_1130	COG0497	DNA recombination
BA_1131	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA_1132	COG2224	Isocitrate lyase
BA_1135	COG1278	Cold shock
BA_1138	COG4903	ComK protein
BA_1139	COG0398	Pfam SNARE associated Golgi protein
BA_1141	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BA_1142	COG1074	ATP-dependent DNA helicase activity
BA_1152	COG0179	Fumarylacetoacetate (FAA) hydrolase
BA_1157	COG0367	asparagine synthase
BA_1159	COG0753	catalase activity
BA_1167	COG2996	Protein conserved in bacteria
BA_1169	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA_1171	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_1174	COG0561	phosphatase activity
BA_1177	COG0542	response to heat
BA_1180	COG2267	carboxylic ester hydrolase activity
BA_1184	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_1185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA_1186	COG5504	Zn-dependent protease
BA_1188	COG0180	Tryptophanyl-tRNA synthetase
BA_1191	COG4166	transmembrane transport
BA_1192	COG0601	transmembrane transport
BA_1193	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA_1194	COG0444	Belongs to the ABC transporter superfamily
BA_1195	COG4608	Belongs to the ABC transporter superfamily
BA_1196	COG0534	Mate efflux family protein
BA_1197	COG4166	transmembrane transport
BA_1200	COG1393	Belongs to the ArsC family
BA_1201	COG0861	Integral membrane protein TerC family
BA_1203	COG4862	establishment of competence for transformation
BA_1204	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA_1206	COG1164	Oligoendopeptidase f
BA_1209	COG2346	COG2346, Truncated hemoglobins
BA_1210	COG4116	CYTH
BA_1212	COG2357	RelA SpoT domain protein
BA_1213	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA_1214	COG0564	pseudouridine synthase activity
BA_1219	COG1216	Glycosyl transferase, family 2
BA_1224	COG0457	Tetratricopeptide repeat
BA_1224	COG0463	Glycosyl transferase, family 2
BA_1228	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BA_1231	COG1091	dTDP-4-dehydrorhamnose reductase activity
BA_1240	COG2153	protein acetylation
BA_1241	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BA_1242	COG2382	esterase
BA_1245	COG5492	domain, Protein
BA_1246	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA_1249	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BA_1249	COG0512	Glutamine amidotransferase of anthranilate synthase
BA_1256	COG1620	l-lactate permease
BA_1257	COG5634	Uncharacterized conserved protein (DUF2278)
BA_1269	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA_1271	COG1476	TRANSCRIPTIONal
BA_1282	COG2226	methyltransferase
BA_1286	COG1686	Belongs to the peptidase S11 family
BA_1287	COG0681	Belongs to the peptidase S26 family
BA_1296	COG1012	belongs to the aldehyde dehydrogenase family
BA_1297	COG3842	ATPase activity
BA_1298	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA_1299	COG1177	transmembrane transport
BA_1300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA_1302	COG2409	Drug exporters of the RND superfamily
BA_1304	COG0564	pseudouridine synthase activity
BA_1306	COG2340	Cysteine-rich secretory protein family
BA_1308	COG0247	lactate metabolic process
BA_1309	COG0277	FAD linked oxidase domain protein
BA_1310	COG3835	regulator
BA_1312	COG0745	RESPONSE REGULATOR receiver
BA_1313	COG5002	protein histidine kinase activity
BA_1314	COG2186	Transcriptional regulator
BA_1318	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BA_1321	COG2116	formate transmembrane transporter activity
BA_1322	COG0861	Integral membrane protein TerC family
BA_1323	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA_1326	COG2030	dehydratase
BA_1330	COG1028	Short-chain dehydrogenase reductase Sdr
BA_1331	COG3243	poly(R)-hydroxyalkanoic acid synthase
BA_1333	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA_1337	COG1840	ABC-type Fe3 transport system, periplasmic component
BA_1340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BA_1343	COG1349	DNA-binding transcription factor activity
BA_1349	COG2861	carbohydrate metabolic process
BA_1351	COG3852	Histidine kinase
BA_1352	COG1846	Transcriptional regulator
BA_1354	COG2318	DinB family
BA_1356	COG5002	protein histidine kinase activity
BA_1360	COG0720	synthase
BA_1363	COG4873	Protein conserved in bacteria
BA_1369	COG1780	Probably involved in ribonucleotide reductase function
BA_1372	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA_1373	COG1725	Transcriptional regulator
BA_1374	COG1131	(ABC) transporter
BA_1376	COG1131	(ABC) transporter
BA_1377	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BA_1380	COG1522	sequence-specific DNA binding
BA_1382	COG1335	isochorismatase
BA_1384	COG1619	proteins homologs of microcin C7 resistance protein MccF
BA_1385	COG2070	2-Nitropropane dioxygenase
BA_1386	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BA_1388	COG1696	Membrane protein involved in D-alanine export
BA_1394	COG0716	FMN binding
BA_1397	COG3173	Aminoglycoside phosphotransferase
BA_1402	COG0534	Mate efflux family protein
BA_1403	COG1968	undecaprenyl-diphosphatase activity
BA_1406	COG1846	Transcriptional regulator
BA_1408	COG1301	dicarboxylic acid transport
BA_1409	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA_1410	COG4709	membrane
BA_1411	COG3874	Sporulation protein YtfJ
BA_1416	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA_1417	COG0028	Belongs to the TPP enzyme family
BA_1418	COG0440	acetolactate synthase activity
BA_1419	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA_1421	COG0473	3-isopropylmalate dehydrogenase activity
BA_1426	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA_1432	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BA_1435	COG1183	phosphatidylcholine synthase activity
BA_1436	COG1368	sulfuric ester hydrolase activity
BA_1438	COG0019	diaminopimelate decarboxylase activity
BA_1442	COG0529	Catalyzes the synthesis of activated sulfate
BA_1443	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA_1447	COG1648	precorrin-2 dehydrogenase activity
BA_1448	COG0733	neurotransmitter:sodium symporter activity
BA_1452	COG1757	Na H antiporter
BA_1455	COG4758	membrane
BA_1456	COG4585	Histidine kinase
BA_1457	COG2197	response regulator
BA_1459	COG1114	Component of the transport system for branched-chain amino acids
BA_1462	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA_1467	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BA_1467	COG1017	nitric oxide dioxygenase activity
BA_1470	COG0730	response to heat
BA_1471	COG0306	phosphate transporter
BA_1472	COG1392	Phosphate transport regulator
BA_1474	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA_1479	COG1801	Protein of unknown function DUF72
BA_1481	COG0582	viral genome integration into host DNA
BA_1482	COG5002	protein histidine kinase activity
BA_1486	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BA_1486	COG0392	lysyltransferase activity
BA_1489	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA_1490	COG1686	Belongs to the peptidase S11 family
BA_1491	COG2715	membrane protein required for spore maturation
BA_1492	COG0700	Nucleoside recognition
BA_1493	COG1187	pseudouridine synthase activity
BA_1495	COG1333	cytochrome c biogenesis protein
BA_1496	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA_1497	COG0745	RESPONSE REGULATOR receiver
BA_1498	COG5002	protein histidine kinase activity
BA_1499	COG2096	Adenosyltransferase
BA_1502	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BA_1503	COG1141	Ferredoxin
BA_1504	COG4955	Helix-turn-helix domain
BA_1505	COG0514	ATP-dependent DNA helicase (RecQ)
BA_1506	COG1266	CAAX protease self-immunity
BA_1510	COG4862	establishment of competence for transformation
BA_1511	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA_1515	COG0492	ferredoxin-NADP+ reductase activity
BA_1530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA_1533	COG0142	geranyltranstransferase activity
BA_1535	COG0142	geranyltranstransferase activity
BA_1536	COG0105	UTP biosynthetic process
BA_1539	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA_1541	COG0457	Tetratricopeptide repeat
BA_1545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BA_1548	COG4347	Protein of unknown function (DUF1405)
BA_1551	COG2738	Putative neutral zinc metallopeptidase
BA_1553	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_1554	COG1694	Mazg nucleotide pyrophosphohydrolase
BA_1557	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA_1558	COG0438	transferase activity, transferring glycosyl groups
BA_1565	COG1199	ATP-dependent helicase activity
BA_1565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BA_1569	COG3935	DnaD domain protein
BA_1570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BA_1572	COG4499	WXG100 protein secretion system (Wss), protein YukC
BA_1572	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA_1582	COG4474	Belongs to the UPF0398 family
BA_1584	COG0116	Belongs to the methyltransferase superfamily
BA_1586	COG1199	ATP-dependent helicase activity
BA_1587	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BA_1589	COG3173	Aminoglycoside phosphotransferase
BA_1590	COG0024	Methionine aminopeptidase
BA_1592	COG2233	PERMEase
BA_1593	COG2311	Membrane
BA_1595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA_1597	COG0456	acetyltransferase
BA_1602	COG0754	glutathionylspermidine amidase activity
BA_1606	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA_1612	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA_1615	COG1215	transferase activity, transferring glycosyl groups
BA_1619	COG0454	-acetyltransferase
BA_1623	COG0328	RNA-DNA hybrid ribonuclease activity
BA_1631	COG1280	lysine exporter protein (LysE YggA)
BA_1634	COG3162	membrane
BA_1635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA_1636	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA_1639	COG0475	glutathione-regulated potassium exporter activity
BA_1640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA_1641	COG0789	Transcriptional regulator
BA_1641	COG4978	Transcriptional regulator
BA_1643	COG2323	membrane
BA_1645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BA_1656	COG1923	regulation of RNA biosynthetic process
BA_1658	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA_1659	COG1360	Flagellar Motor Protein
BA_1660	COG2201	protein-glutamate methylesterase activity
BA_1662	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA_1662	COG1776	CheC inhibitor of MCP methylation
BA_1665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BA_1669	COG1256	bacterial-type flagellum assembly
BA_1674	COG1815	bacterial-type flagellum-dependent cell motility
BA_1675	COG1558	bacterial-type flagellum-dependent cell motility
BA_1676	COG1677	Flagellar hook-basal body complex protein FliE
BA_1679	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA_1681	COG1157	protein secretion by the type III secretion system
BA_1693	COG0463	Glycosyl transferase, family 2
BA_1706	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA_1707	COG0741	lytic transglycosylase activity
BA_1710	COG1776	CheC inhibitor of MCP methylation
BA_1710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA_1712	COG1338	Plays a role in the flagellum-specific transport system
BA_1713	COG1987	bacterial-type flagellum assembly
BA_1715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA_1716	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA_1718	COG1419	protein localization to endoplasmic reticulum
BA_1719	COG4786	Flagellar basal body rod
BA_1720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA_1725	COG1309	transcriptional regulator
BA_1728	COG2329	Antibiotic biosynthesis monooxygenase
BA_1734	COG3842	ATPase activity
BA_1735	COG0725	ABC transporter, periplasmic molybdate-binding protein
BA_1736	COG1177	transmembrane transport
BA_1737	COG1234	tRNA 3'-trailer cleavage
BA_1743	COG1686	Belongs to the peptidase S11 family
BA_1745	COG0406	alpha-ribazole phosphatase activity
BA_1751	COG0367	asparagine synthase
BA_1758	COG1802	Transcriptional regulator
BA_1759	COG0697	spore germination
BA_1760	COG0523	cobalamin synthesis protein
BA_1762	COG0701	Predicted permease
BA_1764	COG1216	Glycosyl transferase, family 2
BA_1764	COG0438	transferase activity, transferring glycosyl groups
BA_1766	COG1757	Na H antiporter
BA_1767	COG0114	fumarate hydratase activity
BA_1774	COG3340	Belongs to the peptidase S51 family
BA_1778	COG0785	Cytochrome C biogenesis protein
BA_1785	COG2733	membrane
BA_1793	COG1131	(ABC) transporter
BA_1796	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA_1797	COG0528	UMP kinase activity
BA_1800	COG1027	Aspartate ammonia-lyase
BA_1801	COG0281	malic enzyme
BA_1802	COG4191	Histidine kinase
BA_1803	COG0784	Response regulator, receiver
BA_1804	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA_1816	COG1051	belongs to the nudix hydrolase family
BA_1817	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA_1822	COG1966	Carbon starvation protein
BA_1826	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_1828	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA_1830	COG2223	nitrite transmembrane transporter activity
BA_1831	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA_1834	COG2244	polysaccharide biosynthetic process
BA_1835	COG0733	neurotransmitter:sodium symporter activity
BA_1837	COG5566	PFAM Mor transcription activator
BA_1838	COG2323	membrane
BA_1842	COG2084	Dehydrogenase
BA_1846	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA_1849	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA_1850	COG0028	Belongs to the TPP enzyme family
BA_1852	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA_1854	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BA_1858	COG2814	Major facilitator Superfamily
BA_1859	COG3384	dioxygenase
BA_1861	COG3279	Response regulator of the LytR AlgR family
BA_1862	COG0427	acetyl-CoA hydrolase
BA_1866	COG1073	alpha beta
BA_1867	COG1131	(ABC) transporter
BA_1876	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_1880	COG1914	H( )-stimulated, divalent metal cation uptake system
BA_1884	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA_1891	COG2390	Transcriptional regulator
BA_1893	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_1894	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BA_1896	COG4846	Membrane protein involved in cytochrome C biogenesis
BA_1897	COG4224	UPF0291 protein
BA_1901	COG0006	proline dipeptidase activity
BA_1902	COG2132	Multicopper oxidase
BA_1908	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA_1912	COG2372	response to copper ion
BA_1912	COG1276	copper resistance
BA_1913	COG4549	nuclear export factor GLE1
BA_1915	COG0697	spore germination
BA_1916	COG0583	DNA-binding transcription factor activity
BA_1917	COG1959	2 iron, 2 sulfur cluster binding
BA_1918	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BA_1919	COG0778	Nitroreductase
BA_1922	COG0628	permease
BA_1923	COG0039	L-malate dehydrogenase activity
BA_1924	COG1231	oxidoreductase activity
BA_1925	COG0523	cobalamin synthesis protein
BA_1928	COG0318	PFAM AMP-dependent synthetase and ligase
BA_1929	COG2030	dehydratase
BA_1930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_1933	COG0411	ABC transporter
BA_1937	COG0583	DNA-binding transcription factor activity
BA_1941	COG1846	Transcriptional regulator
BA_1943	COG1271	oxidase subunit
BA_1944	COG1294	oxidase, subunit
BA_1945	COG4988	ABC transporter
BA_1946	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BA_1950	COG1686	Belongs to the peptidase S11 family
BA_1952	COG0791	NLP P60 protein
BA_1952	COG1388	LysM domain
BA_1955	COG0745	RESPONSE REGULATOR receiver
BA_1956	COG5002	protein histidine kinase activity
BA_1958	COG0300	oxidoreductase activity
BA_1961	COG0726	polysaccharide deacetylase
BA_1968	COG0460	homoserine dehydrogenase
BA_1973	COG1316	TRANSCRIPTIONal
BA_1975	COG0745	RESPONSE REGULATOR receiver
BA_1976	COG5002	protein histidine kinase activity
BA_1977	COG0726	polysaccharide deacetylase
BA_1979	COG1285	pathogenesis
BA_1980	COG1247	-acetyltransferase
BA_1982	COG4264	IucA IucC family
BA_1983	COG0318	PFAM AMP-dependent synthetase and ligase
BA_1986	COG1082	Xylose isomerase domain protein TIM barrel
BA_1989	COG1279	arginine transmembrane transporter activity
BA_1992	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA_2000	COG2002	toxin-antitoxin pair type II binding
BA_2001	COG1404	Belongs to the peptidase S8 family
BA_2002	COG0640	Transcriptional regulator
BA_2003	COG0667	Aldo Keto reductase
BA_2004	COG2814	Major facilitator Superfamily
BA_2009	COG0840	transmembrane signaling receptor activity
BA_2012	COG3949	Membrane
BA_2013	COG0783	Belongs to the Dps family
BA_2016	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA_2018	COG1231	oxidoreductase activity
BA_2020	COG4989	oxidoreductase activity
BA_2021	COG0523	cobalamin synthesis protein
BA_2022	COG0456	acetyltransferase
BA_2035	COG3443	Belongs to the bacterial solute-binding protein 9 family
BA_2035	COG0803	Belongs to the bacterial solute-binding protein 9 family
BA_2037	COG0702	epimerase
BA_2039	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA_2041	COG4166	transmembrane transport
BA_2044	COG0406	alpha-ribazole phosphatase activity
BA_2046	COG5337	Spore coat protein CotH
BA_2047	COG1051	belongs to the nudix hydrolase family
BA_2048	COG0586	Pfam SNARE associated Golgi protein
BA_2049	COG2244	polysaccharide biosynthetic process
BA_2051	COG0701	Predicted permease
BA_2052	COG3689	TIGRFAM TIGR03943 family protein
BA_2053	COG1607	acyl-coa hydrolase
BA_2054	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA_2057	COG0702	epimerase
BA_2058	COG2839	Protein conserved in bacteria
BA_2059	COG1253	flavin adenine dinucleotide binding
BA_2063	COG1114	Component of the transport system for branched-chain amino acids
BA_2064	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_2068	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA_2070	COG1876	peptidase activity
BA_2072	COG0154	amidase activity
BA_2073	COG2211	Major facilitator Superfamily
BA_2077	COG0561	phosphatase activity
BA_2079	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA_2083	COG1819	glycosyl
BA_2084	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_2085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_2091	COG0456	acetyltransferase
BA_2101	COG3874	Sporulation protein YtfJ
BA_2106	COG2226	methyltransferase
BA_2110	COG1082	Xylose isomerase domain protein TIM barrel
BA_2111	COG0346	lactoylglutathione lyase activity
BA_2113	COG0604	alcohol dehydrogenase
BA_2114	COG1595	DNA-templated transcription, initiation
BA_2119	COG0386	Belongs to the glutathione peroxidase family
BA_2120	COG1305	Transglutaminase-like
BA_2121	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BA_2122	COG0714	Associated with various cellular activities
BA_2125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BA_2126	COG1140	nitrate reductase beta subunit
BA_2127	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BA_2128	COG2181	nitrate reductase activity
BA_2132	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA_2133	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA_2134	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA_2135	COG0303	'Molybdopterin
BA_2136	COG0314	molybdopterin synthase activity
BA_2138	COG2223	nitrite transmembrane transporter activity
BA_2142	COG1648	precorrin-2 dehydrogenase activity
BA_2144	COG1587	Uroporphyrinogen-III synthase
BA_2144	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA_2145	COG2146	nitrite reductase [NAD(P)H] activity
BA_2146	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA_2147	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BA_2154	COG2359	stage V sporulation protein S
BA_2159	COG5632	N-Acetylmuramoyl-L-alanine amidase
BA_2163	COG1418	mRNA catabolic process
BA_2164	COG0488	(ABC) transporter
BA_2168	COG0629	single-stranded DNA binding
BA_2171	COG1413	lyase activity
BA_2174	COG2136	Putative SAM-dependent methyltransferase
BA_2174	COG2521	methyltransferase
BA_2175	COG0018	arginyl-trna synthetase
BA_2181	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BA_2186	COG0017	Asparaginyl-tRNA synthetase
BA_2190	COG1674	ftsk spoiiie
BA_2210	COG1929	Belongs to the glycerate kinase type-1 family
BA_2211	COG0471	metal ion transport
BA_2212	COG0745	RESPONSE REGULATOR receiver
BA_2213	COG3850	Histidine kinase
BA_2213	COG5002	protein histidine kinase activity
BA_2216	COG0733	neurotransmitter:sodium symporter activity
BA_2221	COG2610	gluconate transmembrane transporter activity
BA_2222	COG1454	alcohol dehydrogenase
BA_2223	COG1794	racemase activity, acting on amino acids and derivatives
BA_2225	COG0456	acetyltransferase
BA_2228	COG1131	(ABC) transporter
BA_2229	COG4473	ABC transporter
BA_2231	COG0546	phosphoglycolate phosphatase activity
BA_2235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA_2238	COG0768	penicillin binding
BA_2239	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA_2240	COG0204	Acyl-transferase
BA_2241	COG1272	protein, Hemolysin III
BA_2243	COG0805	protein transport
BA_2246	COG1307	EDD domain protein, DegV family
BA_2247	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BA_2249	COG1999	signal sequence binding
BA_2250	COG0071	Belongs to the small heat shock protein (HSP20) family
BA_2251	COG0367	asparagine synthase
BA_2255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_2256	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA_2261	COG1051	belongs to the nudix hydrolase family
BA_2263	COG0668	transmembrane transport
BA_2264	COG2203	Gaf domain
BA_2264	COG4585	Histidine kinase
BA_2265	COG2197	response regulator
BA_2267	COG1064	alcohol dehydrogenase
BA_2279	COG1125	glycine betaine transport
BA_2279	COG0517	IMP dehydrogenase activity
BA_2280	COG1174	glycine betaine transport
BA_2288	COG1253	flavin adenine dinucleotide binding
BA_2289	COG1012	belongs to the aldehyde dehydrogenase family
BA_2290	COG5506	Protein of unknown function (DUF1694)
BA_2294	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA_2295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BA_2296	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BA_2297	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA_2298	COG0456	acetyltransferase
BA_2299	COG3829	transcription factor binding
BA_2300	COG1509	lysine 2,3-aminomutase activity
BA_2308	COG4326	sporulation control protein
BA_2309	COG0671	phosphoesterase, PA-phosphatase related
BA_2310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BA_2311	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA_2317	COG1787	Restriction endonuclease
BA_2317	COG1715	Restriction endonuclease
BA_2336	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA_2345	COG4499	WXG100 protein secretion system (Wss), protein YukC
BA_2345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA_2346	COG2814	Major facilitator Superfamily
BA_2347	COG4841	protein insertion into membrane
BA_2348	COG0372	Belongs to the citrate synthase family
BA_2349	COG2079	MmgE PrpD family protein
BA_2350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA_2352	COG1960	acyl-CoA dehydrogenase activity
BA_2353	COG2084	Dehydrogenase
BA_2354	COG1012	belongs to the aldehyde dehydrogenase family
BA_2355	COG1280	lysine exporter protein (LysE YggA)
BA_2356	COG1024	Enoyl-CoA hydratase
BA_2359	COG0420	3'-5' exonuclease activity
BA_2360	COG0419	ATPase involved in DNA repair
BA_2367	COG2223	nitrite transmembrane transporter activity
BA_2368	COG1028	Short-chain dehydrogenase reductase Sdr
BA_2369	COG1169	isochorismate synthase
BA_2370	COG1021	2,3-dihydroxybenzoate-AMP ligase
BA_2371	COG1535	isochorismatase
BA_2371	COG3433	isochorismatase activity
BA_2372	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BA_2373	COG3251	PFAM MbtH domain protein
BA_2374	COG2814	Major facilitator Superfamily
BA_2377	COG0776	regulation of translation
BA_2379	COG2318	DinB family
BA_2381	COG1115	amino acid carrier protein
BA_2385	COG2329	Antibiotic biosynthesis monooxygenase
BA_2386	COG1187	pseudouridine synthase activity
BA_2388	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA_2392	COG0596	Alpha beta hydrolase
BA_2393	COG2814	Major facilitator Superfamily
BA_2396	COG2226	methyltransferase
BA_2405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_2412	COG1247	-acetyltransferase
BA_2420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_2422	COG1278	Cold shock
BA_2425	COG0010	Belongs to the arginase family
BA_2426	COG0561	phosphatase activity
BA_2435	COG0583	DNA-binding transcription factor activity
BA_2436	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA_2439	COG0583	DNA-binding transcription factor activity
BA_2440	COG2258	MOSC domain
BA_2443	COG1132	(ABC) transporter
BA_2444	COG1132	(ABC) transporter
BA_2448	COG1396	sequence-specific DNA binding
BA_2454	COG1595	DNA-templated transcription, initiation
BA_2460	COG1649	PFAM Uncharacterised BCR, COG1649
BA_2466	COG2971	BadF BadG BcrA BcrD
BA_2467	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA_2468	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA_2472	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_2479	COG1309	transcriptional regulator
BA_2482	COG1136	(ABC) transporter
BA_2482	COG0577	efflux transmembrane transporter activity
BA_2483	COG3615	Tellurite resistance protein tehB
BA_2483	COG0500	methyltransferase
BA_2485	COG2226	methyltransferase
BA_2486	COG3961	Belongs to the TPP enzyme family
BA_2487	COG1846	Transcriptional regulator
BA_2498	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA_2502	COG1595	DNA-templated transcription, initiation
BA_2504	COG0768	penicillin binding
BA_2507	COG2367	Beta-lactamase
BA_2508	COG0671	phosphoesterase, PA-phosphatase related
BA_2509	COG1609	Transcriptional regulator
BA_2510	COG2814	Major facilitator Superfamily
BA_2511	COG0673	inositol 2-dehydrogenase activity
BA_2513	COG1012	belongs to the aldehyde dehydrogenase family
BA_2517	COG3718	enzyme involved in inositol metabolism
BA_2522	COG0457	Tetratricopeptide repeat
BA_2523	COG1476	TRANSCRIPTIONal
BA_2526	COG1876	peptidase activity
BA_2530	COG1309	transcriptional regulator
BA_2534	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_2537	COG1252	NADH dehydrogenase
BA_2538	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_2541	COG1131	(ABC) transporter
BA_2543	COG1309	transcriptional regulator
BA_2547	COG1960	acyl-CoA dehydrogenase activity
BA_2548	COG0439	Biotin carboxylase
BA_2549	COG0511	ligase activity, forming carbon-carbon bonds
BA_2550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA_2551	COG1024	Enoyl-CoA hydratase
BA_2552	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BA_2553	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA_2555	COG1247	-acetyltransferase
BA_2556	COG0572	uridine kinase
BA_2558	COG2318	DinB family
BA_2559	COG1686	Belongs to the peptidase S11 family
BA_2564	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BA_2572	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA_2572	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA_2575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA_2577	COG2814	Major facilitator Superfamily
BA_2581	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA_2585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_2588	COG1063	alcohol dehydrogenase
BA_2594	COG3773	Cell wall hydrolase
BA_2597	COG0745	RESPONSE REGULATOR receiver
BA_2603	COG1136	(ABC) transporter
BA_2608	COG0460	homoserine dehydrogenase
BA_2609	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_2611	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BA_2627	COG2124	cytochrome p450
BA_2634	COG0561	phosphatase activity
BA_2636	COG5002	protein histidine kinase activity
BA_2638	COG1819	glycosyl
BA_2639	COG1794	racemase activity, acting on amino acids and derivatives
BA_2641	COG1122	ATPase activity
BA_2644	COG2205	protein histidine kinase activity
BA_2647	COG0604	alcohol dehydrogenase
BA_2650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA_2657	COG0693	protein deglycase activity
BA_2664	COG2814	Major facilitator Superfamily
BA_2668	COG0584	glycerophosphoryl diester phosphodiesterase
BA_2672	COG0697	spore germination
BA_2680	COG2223	nitrite transmembrane transporter activity
BA_2683	COG2816	NAD+ diphosphatase activity
BA_2684	COG0592	DNA-directed DNA polymerase activity
BA_2685	COG1051	belongs to the nudix hydrolase family
BA_2692	COG3878	Protein conserved in bacteria
BA_2702	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA_2705	COG0322	excinuclease ABC activity
BA_2715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA_2720	COG1011	Hydrolase
BA_2724	COG0076	glutamate decarboxylase activity
BA_2728	COG1523	belongs to the glycosyl hydrolase 13 family
BA_2730	COG3227	Zinc metalloprotease (Elastase)
BA_2734	COG0201	protein transport
BA_2736	COG0697	spore germination
BA_2737	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_2743	COG4129	membrane
BA_2744	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_2747	COG2959	enzyme of heme biosynthesis
BA_2748	COG3773	Cell wall hydrolase
BA_2748	COG3409	Peptidoglycan-binding domain 1 protein
BA_2751	COG3483	tryptophan 2,3-dioxygenase activity
BA_2752	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BA_2753	COG3844	kynureninase activity
BA_2754	COG1309	transcriptional regulator
BA_2761	COG3284	Transcriptional regulator
BA_2765	COG1349	DNA-binding transcription factor activity
BA_2769	COG1959	2 iron, 2 sulfur cluster binding
BA_2773	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA_2774	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA_2775	COG0022	dehydrogenase e1 component
BA_2776	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BA_2778	COG1028	Short-chain dehydrogenase reductase Sdr
BA_2779	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BA_2779	COG0456	acetyltransferase
BA_2785	COG4176	ABC-type proline glycine betaine transport system permease component
BA_2786	COG4175	Glycine betaine
BA_2786	COG0517	IMP dehydrogenase activity
BA_2788	COG0740	serine-type endopeptidase activity
BA_2791	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BA_2792	COG2153	protein acetylation
BA_2793	COG3397	chitin binding
BA_2797	COG2205	protein histidine kinase activity
BA_2803	COG2333	competence protein COMEC
BA_2803	COG0658	competence protein
BA_2814	COG3973	AAA domain
BA_2817	COG2105	PFAM AIG2 family protein
BA_2818	COG0514	ATP-dependent DNA helicase (RecQ)
BA_2822	COG4637	Psort location Cytoplasmic, score
BA_2827	COG3397	chitin binding
BA_2829	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BA_2830	COG1115	amino acid carrier protein
BA_2831	COG1012	belongs to the aldehyde dehydrogenase family
BA_2832	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA_2834	COG3938	Belongs to the proline racemase family
BA_2835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA_2842	COG0586	Pfam SNARE associated Golgi protein
BA_2846	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BA_2847	COG0519	Catalyzes the synthesis of GMP from XMP
BA_2848	COG4166	transmembrane transport
BA_2850	COG4948	Mandelate Racemase Muconate Lactonizing
BA_2860	COG2936	dipeptidyl-peptidase activity
BA_2861	COG5002	protein histidine kinase activity
BA_2869	COG1164	Oligoendopeptidase f
BA_2872	COG1307	EDD domain protein, DegV family
BA_2877	COG2814	Major facilitator Superfamily
BA_2879	COG1664	Polymer-forming cytoskeletal
BA_2880	COG0789	Transcriptional regulator
BA_2881	COG4533	DNA binding
BA_2882	COG2814	Major facilitator Superfamily
BA_2882	COG0477	Major facilitator Superfamily
BA_2887	COG2261	transglycosylase associated protein
BA_2890	COG2226	methyltransferase
BA_2899	COG0436	Aminotransferase
BA_2900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA_2901	COG5146	pantothenate kinase activity
BA_2906	COG1131	(ABC) transporter
BA_2916	COG0628	permease
BA_2919	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA_2920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA_2921	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA_2922	COG1116	anion transmembrane transporter activity
BA_2930	COG2746	aminoglycoside 3-N-acetyltransferase activity
BA_2936	COG0697	spore germination
BA_2937	COG2318	DinB family
BA_2941	COG4912	Dna alkylation repair
BA_2944	COG0726	polysaccharide deacetylase
BA_2946	COG0861	Integral membrane protein TerC family
BA_2947	COG1368	sulfuric ester hydrolase activity
BA_2948	COG0488	(ABC) transporter
BA_2951	COG1309	transcriptional regulator
BA_2954	COG0287	Prephenate dehydrogenase
BA_2955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA_2956	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BA_2958	COG1605	Chorismate mutase
BA_2958	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BA_2967	COG1388	LysM domain
BA_2967	COG3584	3D domain protein
BA_2970	COG1595	DNA-templated transcription, initiation
BA_2975	COG1879	ABC-type sugar transport system periplasmic component
BA_2977	COG1172	Belongs to the binding-protein-dependent transport system permease family
BA_2979	COG2390	Transcriptional regulator
BA_2987	COG2329	Antibiotic biosynthesis monooxygenase
BA_2991	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_2993	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BA_2995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA_2996	COG4187	Peptidase family M20/M25/M40
BA_2997	COG1414	Transcriptional regulator
BA_2998	COG0833	amino acid
BA_2999	COG1690	Belongs to the RtcB family
BA_3000	COG3239	Fatty acid desaturase
BA_3001	COG1785	Belongs to the alkaline phosphatase family
BA_3003	COG3655	Transcriptional regulator
BA_3006	COG4377	Putative membrane peptidase family (DUF2324)
BA_3008	COG3279	Response regulator of the LytR AlgR family
BA_3010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_3011	COG0346	lactoylglutathione lyase activity
BA_3016	COG0714	Associated with various cellular activities
BA_3022	COG0463	Glycosyl transferase, family 2
BA_3026	COG0463	Glycosyl transferase, family 2
BA_3029	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA_3030	COG0753	catalase activity
BA_3032	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BA_3038	COG0714	Associated with various cellular activities
BA_3040	COG0778	Nitroreductase
BA_3041	COG1846	Transcriptional regulator
BA_3049	COG1725	Transcriptional regulator
BA_3052	COG0577	efflux transmembrane transporter activity
BA_3052	COG1136	(ABC) transporter
BA_3057	COG2207	Transcriptional regulator
BA_3058	COG0456	acetyltransferase
BA_3062	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_3066	COG0642	Histidine kinase
BA_3067	COG0745	RESPONSE REGULATOR receiver
BA_3068	COG0596	Alpha beta hydrolase
BA_3074	COG0730	response to heat
BA_3076	COG0833	amino acid
BA_3078	COG4335	DNA alkylation repair
BA_3089	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA_3096	COG1984	allophanate hydrolase subunit 2
BA_3097	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BA_3098	COG1414	Transcriptional regulator
BA_3102	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA_3103	COG0640	Transcriptional regulator
BA_3105	COG1960	acyl-CoA dehydrogenase activity
BA_3113	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BA_3116	COG3848	Pyruvate phosphate dikinase
BA_3116	COG0574	Belongs to the PEP-utilizing enzyme family
BA_3118	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_3121	COG5577	PFAM Coat F domain
BA_3123	COG3403	YqcI/YcgG family
BA_3124	COG1280	lysine exporter protein (LysE YggA)
BA_3131	COG1063	alcohol dehydrogenase
BA_3136	COG1027	Aspartate ammonia-lyase
BA_3137	COG0252	asparaginase activity
BA_3138	COG1396	sequence-specific DNA binding
BA_3140	COG0322	excinuclease ABC activity
BA_3141	COG0531	amino acid
BA_3142	COG1114	Component of the transport system for branched-chain amino acids
BA_3143	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA_3145	COG0281	malic enzyme
BA_3150	COG0697	spore germination
BA_3153	COG0784	Response regulator, receiver
BA_3155	COG2066	Belongs to the glutaminase family
BA_3162	COG0737	Belongs to the 5'-nucleotidase family
BA_3164	COG0753	catalase activity
BA_3165	COG2267	carboxylic ester hydrolase activity
BA_3166	COG1335	isochorismatase
BA_3170	COG0583	DNA-binding transcription factor activity
BA_3172	COG1846	Transcriptional regulator
BA_3180	COG0415	Belongs to the DNA photolyase family
BA_3181	COG0288	reversible hydration of carbon dioxide
BA_3183	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BA_3184	COG5609	conserved protein (DUF2294)
BA_3186	COG1575	Belongs to the MenA family. Type 1 subfamily
BA_3187	COG2267	carboxylic ester hydrolase activity
BA_3189	COG0803	Belongs to the bacterial solute-binding protein 9 family
BA_3190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA_3191	COG1121	(ABC) transporter
BA_3197	COG0798	PFAM Bile acid sodium symporter
BA_3198	COG0346	lactoylglutathione lyase activity
BA_3199	COG0640	Transcriptional regulator
BA_3202	COG0443	Heat shock 70 kDa protein
BA_3205	COG1522	sequence-specific DNA binding
BA_3208	COG0346	lactoylglutathione lyase activity
BA_3223	COG2814	Major facilitator Superfamily
BA_3229	COG0745	RESPONSE REGULATOR receiver
BA_3230	COG5002	protein histidine kinase activity
BA_3230	COG3850	Histidine kinase
BA_3236	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BA_3243	COG1476	TRANSCRIPTIONal
BA_3247	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_3248	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA_3251	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_3252	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BA_3255	COG1136	(ABC) transporter
BA_3256	COG0577	efflux transmembrane transporter activity
BA_3260	COG3850	Histidine kinase
BA_3260	COG5002	protein histidine kinase activity
BA_3262	COG2364	Membrane
BA_3263	COG1846	Transcriptional regulator
BA_3265	COG2808	Putative FMN-binding domain
BA_3266	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_3267	COG2271	Major facilitator Superfamily
BA_3268	COG1556	Lactate utilization protein
BA_3269	COG1139	Iron-sulfur cluster binding protein
BA_3271	COG0583	DNA-binding transcription factor activity
BA_3275	COG1619	proteins homologs of microcin C7 resistance protein MccF
BA_3279	COG0738	Major facilitator superfamily
BA_3280	COG0673	inositol 2-dehydrogenase activity
BA_3281	COG0561	phosphatase activity
BA_3283	COG1609	Transcriptional regulator
BA_3284	COG0457	Tetratricopeptide repeat
BA_3288	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA_3296	COG0534	Mate efflux family protein
BA_3302	COG2814	Major facilitator Superfamily
BA_3303	COG1309	transcriptional regulator
BA_3306	COG0814	amino acid
BA_3307	COG1760	l-serine dehydratase
BA_3308	COG1760	l-serine dehydratase
BA_3312	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA_3313	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BA_3315	COG1335	isochorismatase
BA_3316	COG1522	sequence-specific DNA binding
BA_3317	COG0531	amino acid
BA_3320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA_3324	COG1595	DNA-templated transcription, initiation
BA_3327	COG0662	Cupin 2, conserved barrel domain protein
BA_3328	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_3328	COG2207	Transcriptional regulator
BA_3342	COG0477	Major facilitator Superfamily
BA_3344	COG1846	Transcriptional regulator
BA_3345	COG2814	Major facilitator Superfamily
BA_3348	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BA_3349	COG1131	(ABC) transporter
BA_3353	COG2076	Multidrug Resistance protein
BA_3354	COG1309	transcriptional regulator
BA_3356	COG2031	fatty acid transporter
BA_3358	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA_3364	COG1122	ATPase activity
BA_3365	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BA_3368	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BA_3369	COG1288	antiporter activity
BA_3370	COG2356	endonuclease I
BA_3373	COG3620	sequence-specific DNA binding
BA_3374	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA_3375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BA_3376	COG0124	histidyl-tRNA synthetase
BA_3379	COG1733	regulation of RNA biosynthetic process
BA_3380	COG0778	Nitroreductase
BA_3385	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3387	COG1131	(ABC) transporter
BA_3392	COG1011	Hydrolase
BA_3399	COG0346	lactoylglutathione lyase activity
BA_3400	COG1940	carbohydrate kinase activity
BA_3401	COG0738	Major facilitator superfamily
BA_3402	COG0110	maltose O-acetyltransferase activity
BA_3406	COG1136	(ABC) transporter
BA_3408	COG0180	Tryptophanyl-tRNA synthetase
BA_3409	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BA_3410	COG0628	permease
BA_3414	COG2226	methyltransferase
BA_3416	COG0477	Major facilitator Superfamily
BA_3422	COG1253	flavin adenine dinucleotide binding
BA_3423	COG0789	Transcriptional regulator
BA_3424	COG0697	spore germination
BA_3425	COG1357	PFAM Pentapeptide repeats (8 copies)
BA_3426	COG3813	Protein conserved in bacteria
BA_3427	COG2706	6-phosphogluconolactonase activity
BA_3428	COG1070	Carbohydrate kinase
BA_3430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BA_3431	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BA_3433	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BA_3434	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BA_3435	COG0604	alcohol dehydrogenase
BA_3436	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA_3440	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3446	COG0656	L-ascorbic acid biosynthetic process
BA_3447	COG2814	Major facilitator Superfamily
BA_3450	COG0346	lactoylglutathione lyase activity
BA_3451	COG0814	amino acid
BA_3456	COG1393	Belongs to the ArsC family
BA_3457	COG1733	regulation of RNA biosynthetic process
BA_3458	COG2188	Transcriptional regulator
BA_3460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA_3461	COG1733	regulation of RNA biosynthetic process
BA_3462	COG1733	regulation of RNA biosynthetic process
BA_3465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_3469	COG0384	phenazine biosynthesis protein PhzF
BA_3471	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3473	COG0318	PFAM AMP-dependent synthetase and ligase
BA_3475	COG1733	regulation of RNA biosynthetic process
BA_3480	COG0726	polysaccharide deacetylase
BA_3483	COG1191	sigma factor activity
BA_3487	COG1309	transcriptional regulator
BA_3491	COG3152	Membrane
BA_3497	COG1151	hydroxylamine reductase activity
BA_3500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_3501	COG3409	Peptidoglycan-binding domain 1 protein
BA_3501	COG3757	hydrolase, family 25
BA_3508	COG2072	flavoprotein involved in K transport
BA_3516	COG1113	amino acid transport
BA_3518	COG2814	Major facilitator Superfamily
BA_3525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA_3526	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BA_3531	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_3533	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_3534	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_3535	COG3739	integral membrane protein
BA_3536	COG0384	phenazine biosynthesis protein PhzF
BA_3543	COG0583	DNA-binding transcription factor activity
BA_3547	COG1193	negative regulation of DNA recombination
BA_3553	COG1164	Oligoendopeptidase f
BA_3554	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BA_3560	COG0584	glycerophosphoryl diester phosphodiesterase
BA_3565	COG0640	Transcriptional regulator
BA_3566	COG0604	alcohol dehydrogenase
BA_3571	COG2808	Putative FMN-binding domain
BA_3572	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BA_3574	COG0385	Bile acid
BA_3575	COG0277	FAD linked oxidase domain protein
BA_3582	COG1216	Glycosyl transferase, family 2
BA_3583	COG1024	Enoyl-CoA hydratase
BA_3585	COG1285	pathogenesis
BA_3587	COG2514	catechol 2,3-dioxygenase activity
BA_3588	COG2720	vancomycin resistance protein
BA_3594	COG1278	Cold shock
BA_3596	COG0716	FMN binding
BA_3602	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3604	COG0165	Argininosuccinate lyase
BA_3607	COG4145	pantothenate transmembrane transporter activity
BA_3609	COG1012	belongs to the aldehyde dehydrogenase family
BA_3610	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3612	COG1657	PFAM Prenyltransferase squalene oxidase
BA_3613	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BA_3614	COG2962	Rard protein
BA_3615	COG3326	Membrane
BA_3620	COG0489	protein tyrosine kinase activity
BA_3622	COG0314	molybdopterin synthase activity
BA_3623	COG0303	'Molybdopterin
BA_3624	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA_3625	COG2116	formate transmembrane transporter activity
BA_3628	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA_3629	COG5609	conserved protein (DUF2294)
BA_3630	COG2427	Protein of unknown function (DUF1641)
BA_3631	COG3383	formate dehydrogenase (NAD+) activity
BA_3633	COG0697	spore germination
BA_3641	COG2226	methyltransferase
BA_3642	COG4166	transmembrane transport
BA_3644	COG4166	transmembrane transport
BA_3645	COG4166	transmembrane transport
BA_3647	COG1316	TRANSCRIPTIONal
BA_3649	COG1595	DNA-templated transcription, initiation
BA_3653	COG1131	(ABC) transporter
BA_3655	COG0673	inositol 2-dehydrogenase activity
BA_3656	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BA_3657	COG0187	DNA topoisomerase II activity
BA_3659	COG1832	CoA-binding protein
BA_3660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA_3661	COG0745	RESPONSE REGULATOR receiver
BA_3665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA_3666	COG4841	protein insertion into membrane
BA_3667	COG0824	Thioesterase
BA_3674	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA_3676	COG2274	protein secretion by the type I secretion system
BA_3677	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BA_3679	COG0726	polysaccharide deacetylase
BA_3682	COG2211	Major facilitator Superfamily
BA_3684	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA_3687	COG0183	Belongs to the thiolase family
BA_3688	COG0318	PFAM AMP-dependent synthetase and ligase
BA_3689	COG1268	BioY protein
BA_3690	COG0318	PFAM AMP-dependent synthetase and ligase
BA_3700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_3702	COG5002	protein histidine kinase activity
BA_3703	COG0400	carboxylic ester hydrolase activity
BA_3704	COG0346	lactoylglutathione lyase activity
BA_3705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA_3706	COG0069	glutamate synthase activity
BA_3707	COG1902	pentaerythritol trinitrate reductase activity
BA_3708	COG1329	Transcriptional regulator
BA_3709	COG0010	Belongs to the arginase family
BA_3714	COG2226	methyltransferase
BA_3726	COG4846	Membrane protein involved in cytochrome C biogenesis
BA_3727	COG0785	Cytochrome C biogenesis protein
BA_3729	COG0583	DNA-binding transcription factor activity
BA_3730	COG1380	Effector of murein hydrolase LrgA
BA_3731	COG1346	cytolysis
BA_3737	COG5632	N-Acetylmuramoyl-L-alanine amidase
BA_3737	COG3409	Peptidoglycan-binding domain 1 protein
BA_3740	COG1132	(ABC) transporter
BA_3741	COG1132	(ABC) transporter
BA_3748	COG3639	organic phosphonate transmembrane transporter activity
BA_3749	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BA_3753	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BA_3757	COG1695	Transcriptional regulator
BA_3767	COG1388	LysM domain
BA_3767	COG5632	N-Acetylmuramoyl-L-alanine amidase
BA_3767	COG3409	Peptidoglycan-binding domain 1 protein
BA_3768	COG4824	toxin secretion phage lysis holin
BA_3803	COG1595	DNA-templated transcription, initiation
BA_3813	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BA_3829	COG1396	sequence-specific DNA binding
BA_3833	COG0174	glutamine synthetase
BA_3834	COG0789	Transcriptional regulator
BA_3835	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BA_3836	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA_3837	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA_3838	COG2860	membrane
BA_3839	COG0464	growth
BA_3845	COG3584	3D domain protein
BA_3845	COG1388	LysM domain
BA_3846	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA_3846	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA_3846	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA_3847	COG1105	Belongs to the carbohydrate kinase PfkB family
BA_3848	COG1349	DNA-binding transcription factor activity
BA_3850	COG2322	membrane
BA_3853	COG1113	amino acid transport
BA_3856	COG1408	metallophosphoesterase
BA_3857	COG2116	formate transmembrane transporter activity
BA_3859	COG2217	Heavy metal translocating P-type atpase
BA_3860	COG2608	mercury ion transmembrane transporter activity
BA_3861	COG1937	Protein conserved in bacteria
BA_3863	COG2819	hydrolase of the alpha beta superfamily
BA_3864	COG1120	ATPase activity
BA_3865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_3866	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_3868	COG0708	Exodeoxyribonuclease III
BA_3869	COG2169	Transcriptional regulator
BA_3870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BA_3871	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BA_3873	COG2364	Membrane
BA_3877	COG2267	carboxylic ester hydrolase activity
BA_3878	COG0346	lactoylglutathione lyase activity
BA_3879	COG5001	Diguanylate cyclase
BA_3879	COG3300	MHYT domain
BA_3884	COG1346	cytolysis
BA_3885	COG1380	Effector of murein hydrolase LrgA
BA_3886	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA_3887	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA_3887	COG0596	Alpha beta hydrolase
BA_3888	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BA_3892	COG1404	Belongs to the peptidase S8 family
BA_3893	COG3773	Cell wall hydrolase
BA_3894	COG0562	UDP-galactopyranose mutase
BA_3895	COG1368	sulfuric ester hydrolase activity
BA_3896	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BA_3898	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BA_3907	COG4550	Control of competence regulator ComK, YlbF/YmcA
BA_3908	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA_3909	COG1013	pyruvate-flavodoxin oxidoreductase activity
BA_3910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BA_3910	COG0674	pyruvate-flavodoxin oxidoreductase activity
BA_3912	COG2359	stage V sporulation protein S
BA_3913	COG1692	metallophosphoesterase
BA_3917	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA_3918	COG1426	Protein conserved in bacteria
BA_3921	COG0300	oxidoreductase activity
BA_3922	COG0612	Peptidase, M16
BA_3923	COG0612	Peptidase, M16
BA_3928	COG2188	Transcriptional regulator
BA_3930	COG1674	ftsk spoiiie
BA_3932	COG0740	serine-type endopeptidase activity
BA_3933	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA_3936	COG0527	aspartate kinase activity
BA_3937	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA_3938	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA_3939	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA_3941	COG1873	PFAM PRC-barrel domain
BA_3942	COG0612	Peptidase, M16
BA_3943	COG0726	polysaccharide deacetylase
BA_3946	COG0196	riboflavin kinase activity
BA_3947	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BA_3949	COG1550	Protein conserved in bacteria
BA_3951	COG1358	cellular component organization or biogenesis
BA_3952	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BA_3953	COG0195	Participates in both transcription termination and antitermination
BA_3958	COG0750	zinc metalloprotease
BA_3959	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BA_3960	COG4589	Belongs to the CDS family
BA_3961	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BA_3963	COG0528	UMP kinase activity
BA_3969	COG4974	Belongs to the 'phage' integrase family
BA_3971	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA_3973	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BA_3981	COG1837	Belongs to the UPF0109 family
BA_3983	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BA_3985	COG0552	protein localization to endoplasmic reticulum
BA_3986	COG1196	nuclear chromosome segregation
BA_3989	COG1028	Short-chain dehydrogenase reductase Sdr
BA_3990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BA_3993	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA_3994	COG1461	Dihydroxyacetone kinase
BA_3995	COG1302	Protein conserved in bacteria
BA_3997	COG1564	THIamine pyrophosphokinase
BA_3998	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BA_3999	COG1162	GTPase activity
BA_4000	COG0515	serine threonine protein kinase
BA_4000	COG2815	serine threonine protein kinase
BA_4001	COG0631	protein serine/threonine phosphatase activity
BA_4003	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA_4003	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA_4005	COG0242	peptide deformylase activity
BA_4006	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA_4007	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA_4009	COG0194	GDP metabolic process
BA_4011	COG1561	YicC-like family, N-terminal region
BA_4012	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BA_4014	COG0006	proline dipeptidase activity
BA_4018	COG3069	C4-dicarboxylate transmembrane transporter activity
BA_4026	COG0505	Belongs to the CarA family
BA_4031	COG0564	pseudouridine synthase activity
BA_4034	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BA_4035	COG3599	regulation of cell shape
BA_4036	COG2302	S4 RNA-binding domain
BA_4037	COG0762	integral membrane protein
BA_4039	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BA_4041	COG1873	PFAM PRC-barrel domain
BA_4042	COG1191	sigma factor activity
BA_4043	COG1191	sigma factor activity
BA_4045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BA_4046	COG0849	cell division
BA_4047	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BA_4048	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA_4049	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA_4050	COG0772	Belongs to the SEDS family
BA_4053	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BA_4054	COG0768	penicillin binding
BA_4056	COG4839	cell division protein FtsL
BA_4059	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA_4063	COG1399	metal-binding, possibly nucleic acid-binding protein
BA_4074	COG4824	toxin secretion phage lysis holin
BA_4094	COG4626	Terminase
BA_4094	COG1802	Transcriptional regulator
BA_4099	COG0582	viral genome integration into host DNA
BA_4115	COG1191	sigma factor activity
BA_4120	COG1484	DNA-dependent DNA replication
BA_4126	COG1396	sequence-specific DNA binding
BA_4130	COG1396	sequence-specific DNA binding
BA_4134	COG0582	viral genome integration into host DNA
BA_4136	COG3480	Lon protease (S16) C-terminal proteolytic domain
BA_4137	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA_4138	COG3314	Sporulation integral membrane protein YlbJ
BA_4140	COG0742	ribosomal rna small subunit methyltransferase
BA_4143	COG3679	Belongs to the UPF0342 family
BA_4144	COG0406	alpha-ribazole phosphatase activity
BA_4147	COG2340	Cysteine-rich secretory protein family
BA_4150	COG3336	cytochrome c oxidase
BA_4157	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BA_4158	COG0772	Belongs to the SEDS family
BA_4159	COG4838	Belongs to the UPF0358 family
BA_4160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA_4161	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BA_4163	COG4896	Protein conserved in bacteria
BA_4168	COG0483	inositol monophosphate 1-phosphatase activity
BA_4172	COG1982	Orn Lys Arg decarboxylase major
BA_4182	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA_4183	COG0022	dehydrogenase e1 component
BA_4184	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BA_4187	COG0242	peptide deformylase activity
BA_4188	COG0561	phosphatase activity
BA_4190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA_4191	COG0569	domain protein
BA_4195	COG0583	DNA-binding transcription factor activity
BA_4196	COG0517	IMP dehydrogenase activity
BA_4198	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BA_4200	COG4703	Protein of unknown function (DUF1797)
BA_4203	COG2200	EAL domain
BA_4204	COG1028	Short-chain dehydrogenase reductase Sdr
BA_4205	COG1408	metallophosphoesterase
BA_4208	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BA_4216	COG2814	Major facilitator Superfamily
BA_4220	COG3209	COG3209 Rhs family protein
BA_4223	COG2205	protein histidine kinase activity
BA_4225	COG0436	Aminotransferase
BA_4226	COG1609	Transcriptional regulator
BA_4227	COG3833	ABC-type maltose transport systems, permease component
BA_4228	COG1175	transmembrane transport
BA_4229	COG2182	Extracellular solute-binding protein
BA_4231	COG0366	Alpha amylase catalytic
BA_4232	COG3842	ATPase activity
BA_4240	COG0183	Belongs to the thiolase family
BA_4248	COG1695	Transcriptional regulator
BA_4249	COG1028	Short-chain dehydrogenase reductase Sdr
BA_4253	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA_4254	COG0436	Aminotransferase
BA_4258	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BA_4263	COG3706	GGDEF domain
BA_4264	COG0778	Nitroreductase
BA_4269	COG2190	(PTS) system
BA_4269	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA_4269	COG1263	PTS System
BA_4270	COG3711	transcriptional antiterminator
BA_4274	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA_4280	COG1547	Domain of unknown function (DUF309)
BA_4281	COG0456	acetyltransferase
BA_4283	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA_4284	COG4086	secreted protein
BA_4285	COG0561	phosphatase activity
BA_4286	COG0697	spore germination
BA_4288	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_4293	COG0733	neurotransmitter:sodium symporter activity
BA_4297	COG1686	Belongs to the peptidase S11 family
BA_4298	COG1725	Transcriptional regulator
BA_4299	COG1131	(ABC) transporter
BA_4303	COG1846	Transcriptional regulator
BA_4306	COG0598	Magnesium transport protein CorA
BA_4311	COG4974	Belongs to the 'phage' integrase family
BA_4313	COG0735	belongs to the Fur family
BA_4314	COG1300	Membrane
BA_4318	COG0667	Aldo Keto reductase
BA_4319	COG0656	L-ascorbic acid biosynthetic process
BA_4320	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BA_4320	COG0456	acetyltransferase
BA_4322	COG4085	toxin activity
BA_4322	COG1525	nuclease
BA_4322	COG0737	Belongs to the 5'-nucleotidase family
BA_4324	COG0596	Alpha beta hydrolase
BA_4325	COG2056	Na+-H+ antiporter family
BA_4326	COG1609	Transcriptional regulator
BA_4327	COG0456	acetyltransferase
BA_4328	COG1073	alpha beta
BA_4331	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA_4331	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA_4332	COG0307	riboflavin synthase, alpha
BA_4336	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BA_4337	COG4106	trans-aconitate 2-methyltransferase activity
BA_4338	COG2226	methyltransferase
BA_4338	COG1073	alpha beta
BA_4339	COG0156	8-amino-7-oxononanoate synthase activity
BA_4341	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA_4346	COG0737	Belongs to the 5'-nucleotidase family
BA_4348	COG1522	sequence-specific DNA binding
BA_4352	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA_4354	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BA_4357	COG0300	oxidoreductase activity
BA_4359	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA_4360	COG1760	l-serine dehydratase
BA_4361	COG1760	l-serine dehydratase
BA_4366	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA_4368	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA_4369	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_4372	COG1376	ErfK ybiS ycfS ynhG family protein
BA_4373	COG4129	membrane
BA_4374	COG1126	abc transporter atp-binding protein
BA_4375	COG0765	amino acid transport
BA_4376	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA_4380	COG2816	NAD+ diphosphatase activity
BA_4381	COG0772	Belongs to the SEDS family
BA_4382	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA_4383	COG0022	dehydrogenase e1 component
BA_4384	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BA_4385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA_4387	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BA_4388	COG0280	phosphate acetyltransferase
BA_4389	COG3829	transcription factor binding
BA_4389	COG3290	protein histidine kinase activity
BA_4391	COG0584	glycerophosphoryl diester phosphodiesterase
BA_4392	COG3093	addiction module antidote protein HigA
BA_4394	COG0745	RESPONSE REGULATOR receiver
BA_4396	COG0750	zinc metalloprotease
BA_4397	COG0497	DNA recombination
BA_4399	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BA_4402	COG0142	geranyltranstransferase activity
BA_4407	COG1302	Protein conserved in bacteria
BA_4408	COG0439	Biotin carboxylase
BA_4409	COG0511	ligase activity, forming carbon-carbon bonds
BA_4417	COG3854	ATPases associated with a variety of cellular activities
BA_4422	COG0006	proline dipeptidase activity
BA_4425	COG3872	metal-dependent enzyme
BA_4427	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BA_4431	COG0095	Lipoate-protein ligase
BA_4432	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_4433	COG1609	Transcriptional regulator
BA_4435	COG2076	Multidrug Resistance protein
BA_4436	COG2076	Multidrug Resistance protein
BA_4444	COG1131	(ABC) transporter
BA_4445	COG1725	Transcriptional regulator
BA_4450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA_4463	COG4970	Tfp pilus assembly protein FimT
BA_4465	COG1459	type II secretion system
BA_4466	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA_4477	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA_4478	COG0646	methionine synthase
BA_4478	COG1410	methionine synthase
BA_4479	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BA_4479	COG0646	methionine synthase
BA_4480	COG0626	cystathionine gamma-synthase activity
BA_4481	COG0626	cystathionine gamma-synthase activity
BA_4485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_4487	COG1940	carbohydrate kinase activity
BA_4488	COG4483	Protein conserved in bacteria
BA_4489	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BA_4491	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BA_4492	COG0704	Plays a role in the regulation of phosphate uptake
BA_4493	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA_4494	COG0581	inorganic phosphate transmembrane transporter activity
BA_4495	COG0573	inorganic phosphate transmembrane transporter activity
BA_4496	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BA_4498	COG0477	Major facilitator Superfamily
BA_4499	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA_4503	COG0735	belongs to the Fur family
BA_4504	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA_4505	COG1121	(ABC) transporter
BA_4506	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_4512	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BA_4513	COG2384	SAM-dependent methyltransferase
BA_4514	COG2010	Cytochrome c
BA_4515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA_4516	COG0358	DNA primase activity
BA_4521	COG0517	IMP dehydrogenase activity
BA_4524	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BA_4525	COG0295	cytidine deaminase activity
BA_4526	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BA_4528	COG1480	7TM receptor with intracellular HD hydrolase
BA_4529	COG1702	phosphate starvation-inducible protein PhoH
BA_4533	COG1610	YqeY-like protein
BA_4535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA_4536	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BA_4540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BA_4542	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA_4543	COG1733	regulation of RNA biosynthetic process
BA_4548	COG1466	dna polymerase III delta subunit
BA_4551	COG2333	competence protein COMEC
BA_4551	COG0658	competence protein
BA_4552	COG2131	deaminase
BA_4553	COG1596	polysaccharide export
BA_4553	COG1555	photosystem II stabilization
BA_4554	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA_4555	COG2226	methyltransferase
BA_4556	COG0799	negative regulation of ribosome biogenesis
BA_4557	COG1713	HD superfamily hydrolase involved in NAD metabolism
BA_4560	COG1534	Rna-binding protein
BA_4562	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BA_4563	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BA_4566	COG1191	sigma factor activity
BA_4569	COG1595	DNA-templated transcription, initiation
BA_4571	COG0778	Nitroreductase
BA_4572	COG2357	RelA SpoT domain protein
BA_4574	COG1785	Belongs to the alkaline phosphatase family
BA_4577	COG2267	carboxylic ester hydrolase activity
BA_4584	COG1404	Belongs to the peptidase S8 family
BA_4586	COG3186	Phenylalanine-4-hydroxylase
BA_4589	COG2259	Doxx family
BA_4597	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_4599	COG1012	belongs to the aldehyde dehydrogenase family
BA_4599	COG1454	alcohol dehydrogenase
BA_4600	COG0626	cystathionine gamma-synthase activity
BA_4601	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA_4606	COG0768	penicillin binding
BA_4612	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BA_4616	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA_4618	COG0628	permease
BA_4622	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BA_4625	COG0482	sulfurtransferase activity
BA_4626	COG1104	cysteine desulfurase activity
BA_4627	COG1959	2 iron, 2 sulfur cluster binding
BA_4628	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BA_4630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BA_4633	COG0124	histidyl-tRNA synthetase
BA_4637	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA_4639	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BA_4639	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BA_4640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BA_4641	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA_4641	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA_4643	COG2244	polysaccharide biosynthetic process
BA_4644	COG2323	membrane
BA_4646	COG1862	Preprotein translocase
BA_4652	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BA_4655	COG0640	Transcriptional regulator
BA_4661	COG0157	Belongs to the NadC ModD family
BA_4662	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BA_4663	COG1104	cysteine desulfurase activity
BA_4664	COG1827	regulation of RNA biosynthetic process
BA_4665	COG2258	MOSC domain
BA_4666	COG0077	Prephenate dehydratase
BA_4667	COG0577	efflux transmembrane transporter activity
BA_4668	COG0577	efflux transmembrane transporter activity
BA_4669	COG1136	(ABC) transporter
BA_4671	COG0745	RESPONSE REGULATOR receiver
BA_4672	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BA_4673	COG3290	protein histidine kinase activity
BA_4675	COG2868	ribosomal protein
BA_4677	COG1530	ribonuclease E activity
BA_4678	COG1994	Peptidase M50
BA_4679	COG0739	heme binding
BA_4680	COG2894	cell division
BA_4683	COG1792	Involved in formation and maintenance of cell shape
BA_4684	COG1077	Cell shape determining protein MreB Mrl
BA_4689	COG0285	dihydrofolate synthase activity
BA_4690	COG0525	valine-tRNA ligase activity
BA_4692	COG1388	LysM domain
BA_4694	COG0113	porphobilinogen synthase activity
BA_4695	COG1587	Uroporphyrinogen-III synthase
BA_4697	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA_4699	COG1846	Transcriptional regulator
BA_4700	COG1764	response to oxidative stress
BA_4703	COG0470	DNA polymerase III
BA_4703	COG1067	ATP-dependent peptidase activity
BA_4713	COG0622	Phosphoesterase
BA_4714	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BA_4716	COG5401	PFAM Sporulation and spore germination
BA_4721	COG1309	transcriptional regulator
BA_4724	COG2197	response regulator
BA_4725	COG2233	PERMEase
BA_4727	COG0402	S-adenosylhomocysteine deaminase activity
BA_4728	COG0402	S-adenosylhomocysteine deaminase activity
BA_4733	COG0444	Belongs to the ABC transporter superfamily
BA_4734	COG4608	Belongs to the ABC transporter superfamily
BA_4736	COG3279	Response regulator of the LytR AlgR family
BA_4739	COG1983	PspC domain protein
BA_4740	COG1396	sequence-specific DNA binding
BA_4741	COG0697	spore germination
BA_4743	COG1959	2 iron, 2 sulfur cluster binding
BA_4744	COG1668	transmembrane transport
BA_4745	COG4152	abc transporter atp-binding protein
BA_4746	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BA_4748	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA_4750	COG1876	peptidase activity
BA_4751	COG0824	Thioesterase
BA_4753	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BA_4754	COG1053	succinate dehydrogenase
BA_4755	COG2009	succinate dehydrogenase
BA_4756	COG1719	4-vinyl reductase, 4VR
BA_4758	COG3118	belongs to the thioredoxin family
BA_4759	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BA_4760	COG2086	electron transfer activity
BA_4761	COG1024	Enoyl-CoA hydratase
BA_4762	COG1309	transcriptional regulator
BA_4763	COG0318	PFAM AMP-dependent synthetase and ligase
BA_4768	COG2318	DinB family
BA_4774	COG1131	(ABC) transporter
BA_4776	COG2205	protein histidine kinase activity
BA_4777	COG0745	RESPONSE REGULATOR receiver
BA_4779	COG4895	conserved protein (DUF2196)
BA_4780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BA_4783	COG4509	Sortase family
BA_4784	COG1120	ATPase activity
BA_4787	COG5386	Cell surface protein
BA_4789	COG5386	Cell surface protein
BA_4790	COG1114	Component of the transport system for branched-chain amino acids
BA_4792	COG1187	pseudouridine synthase activity
BA_4795	COG1796	DNA polymerase
BA_4795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BA_4796	COG1286	toxin biosynthetic process
BA_4802	COG0017	Asparaginyl-tRNA synthetase
BA_4803	COG0072	phenylalanine-tRNA ligase activity
BA_4803	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_4805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA_4807	COG1418	mRNA catabolic process
BA_4812	COG2814	Major facilitator Superfamily
BA_4813	COG1566	PFAM secretion protein HlyD family protein
BA_4814	COG1309	transcriptional regulator
BA_4815	COG1363	Peptidase, m42
BA_4819	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BA_4820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA_4822	COG1484	DNA-dependent DNA replication
BA_4823	COG3611	Membrane attachment protein
BA_4825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BA_4827	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA_4828	COG0237	dephospho-CoA kinase activity
BA_4829	COG1971	Probably functions as a manganese efflux pump
BA_4830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BA_4831	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA_4831	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA_4832	COG5002	protein histidine kinase activity
BA_4833	COG0745	RESPONSE REGULATOR receiver
BA_4838	COG0538	isocitrate dehydrogenase activity
BA_4839	COG0372	Belongs to the citrate synthase family
BA_4841	COG0628	permease
BA_4842	COG3030	protein affecting phage T7 exclusion by the F plasmid
BA_4847	COG1725	Transcriptional regulator
BA_4848	COG0281	malic enzyme
BA_4849	COG0587	DNA-directed DNA polymerase activity
BA_4852	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BA_4858	COG4109	DRTGG domain
BA_4861	COG0006	proline dipeptidase activity
BA_4868	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_4869	COG0662	Cupin 2, conserved barrel domain protein
BA_4871	COG1476	TRANSCRIPTIONal
BA_4874	COG1028	Short-chain dehydrogenase reductase Sdr
BA_4875	COG0589	response to stress
BA_4884	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_4888	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BA_4889	COG0827	DNA restriction-modification system
BA_4890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BA_4891	COG3874	Sporulation protein YtfJ
BA_4893	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA_4894	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BA_4896	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA_4900	COG1104	cysteine desulfurase activity
BA_4902	COG0583	DNA-binding transcription factor activity
BA_4903	COG0697	spore germination
BA_4905	COG1956	GAF domain-containing protein
BA_4906	COG0626	cystathionine gamma-synthase activity
BA_4911	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BA_4913	COG1595	DNA-templated transcription, initiation
BA_4915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA_4916	COG0454	-acetyltransferase
BA_4917	COG0517	IMP dehydrogenase activity
BA_4918	COG0123	including yeast histone deacetylase and acetoin utilization protein
BA_4920	COG0745	RESPONSE REGULATOR receiver
BA_4922	COG0666	response to abiotic stimulus
BA_4929	COG1609	Transcriptional regulator
BA_4930	COG4851	CamS sex pheromone cAM373 precursor
BA_4931	COG3118	belongs to the thioredoxin family
BA_4933	COG2309	aminopeptidase activity
BA_4937	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_4940	COG1674	ftsk spoiiie
BA_4943	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_4944	COG4848	Belongs to the UPF0354 family
BA_4945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA_4946	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BA_4947	COG1363	Peptidase, m42
BA_4949	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_4952	COG0510	thiamine kinase activity
BA_4953	COG1523	belongs to the glycosyl hydrolase 13 family
BA_4957	COG1349	DNA-binding transcription factor activity
BA_4958	COG1187	pseudouridine synthase activity
BA_4959	COG2244	polysaccharide biosynthetic process
BA_4960	COG2081	HI0933 family
BA_4961	COG2814	Major facilitator Superfamily
BA_4963	COG3832	glyoxalase III activity
BA_4967	COG1329	Transcriptional regulator
BA_4969	COG4975	Glucose uptake
BA_4972	COG0314	molybdopterin synthase activity
BA_4973	COG1763	Mo-molybdopterin cofactor biosynthetic process
BA_4974	COG0303	'Molybdopterin
BA_4976	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA_4981	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA_4983	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA_4992	COG2814	Major facilitator Superfamily
BA_4993	COG0475	glutathione-regulated potassium exporter activity
BA_4994	COG0490	domain, Protein
BA_4995	COG0582	viral genome integration into host DNA
BA_4997	COG1136	(ABC) transporter
BA_5001	COG1242	4 iron, 4 sulfur cluster binding
BA_5002	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BA_5003	COG1131	(ABC) transporter
BA_5005	COG1794	racemase activity, acting on amino acids and derivatives
BA_5009	COG2267	carboxylic ester hydrolase activity
BA_5010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BA_5011	COG0671	phosphoesterase, PA-phosphatase related
BA_5012	COG0438	transferase activity, transferring glycosyl groups
BA_5014	COG0521	Mo-molybdopterin cofactor biosynthetic process
BA_5027	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BA_5028	COG5002	protein histidine kinase activity
BA_5029	COG4191	Histidine kinase
BA_5030	COG2267	carboxylic ester hydrolase activity
BA_5031	COG1368	sulfuric ester hydrolase activity
BA_5036	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BA_5037	COG1116	anion transmembrane transporter activity
BA_5038	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BA_5043	COG0494	nUDIX hydrolase
BA_5049	COG0288	reversible hydration of carbon dioxide
BA_5050	COG1271	oxidase subunit
BA_5051	COG1294	oxidase, subunit
BA_5056	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_5061	COG1842	Phage shock protein A
BA_5067	COG5002	protein histidine kinase activity
BA_5068	COG0745	RESPONSE REGULATOR receiver
BA_5075	COG1597	lipid kinase activity
BA_5082	COG0586	Pfam SNARE associated Golgi protein
BA_5084	COG0577	efflux transmembrane transporter activity
BA_5085	COG1136	(ABC) transporter
BA_5086	COG3708	Transcriptional regulator
BA_5086	COG2207	Transcriptional regulator
BA_5087	COG0745	RESPONSE REGULATOR receiver
BA_5088	COG2205	protein histidine kinase activity
BA_5090	COG0577	efflux transmembrane transporter activity
BA_5091	COG1136	(ABC) transporter
BA_5100	COG3964	amidohydrolase
BA_5107	COG4948	Mandelate Racemase Muconate Lactonizing
BA_5109	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BA_5110	COG0596	Alpha beta hydrolase
BA_5111	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BA_5112	COG1169	isochorismate synthase
BA_5113	COG1575	Belongs to the MenA family. Type 1 subfamily
BA_5114	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA_5115	COG1278	Cold shock
BA_5119	COG0058	SHG alpha-glucan phosphorylase activity
BA_5120	COG0297	glycogen (starch) synthase activity
BA_5121	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BA_5122	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BA_5125	COG0039	L-malate dehydrogenase activity
BA_5127	COG1285	pathogenesis
BA_5128	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BA_5130	COG0166	Belongs to the GPI family
BA_5131	COG2155	Conserved Protein
BA_5132	COG1098	S1 RNA binding domain
BA_5133	COG0436	Aminotransferase
BA_5134	COG1522	sequence-specific DNA binding
BA_5135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA_5136	COG2267	carboxylic ester hydrolase activity
BA_5138	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BA_5142	COG5018	Exonuclease
BA_5143	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BA_5147	COG0423	glycine-tRNA ligase activity
BA_5148	COG2050	protein possibly involved in aromatic compounds catabolism
BA_5150	COG1268	BioY protein
BA_5152	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BA_5153	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA_5156	COG3584	3D domain protein
BA_5159	COG1252	NADH dehydrogenase
BA_5162	COG3708	Transcriptional regulator
BA_5165	COG1683	Conserved Protein
BA_5169	COG0316	Belongs to the HesB IscA family
BA_5173	COG1252	NADH dehydrogenase
BA_5176	COG0390	transport system, permease component
BA_5177	COG2824	Alkylphosphonate utilization operon protein PhnA
BA_5185	COG4837	Protein of unknown function (DUF1462)
BA_5186	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BA_5188	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA_5189	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA_5191	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA_5192	COG0647	UMP catabolic process
BA_5194	COG2445	Protein of unknown function DUF86
BA_5195	COG1494	fructose-1,6-bisphosphatase
BA_5198	COG4470	Protein conserved in bacteria
BA_5200	COG0789	Transcriptional regulator
BA_5201	COG4377	Putative membrane peptidase family (DUF2324)
BA_5206	COG0739	heme binding
BA_5208	COG3377	Domain of unknown function (DUF1805)
BA_5211	COG1695	Transcriptional regulator
BA_5213	COG0719	Fe-S assembly protein
BA_5214	COG0822	iron-sulfur transferase activity
BA_5215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA_5216	COG0719	Fe-S assembly protein
BA_5217	COG0396	ATPase activity
BA_5219	COG1464	Belongs to the NlpA lipoprotein family
BA_5220	COG1464	Belongs to the NlpA lipoprotein family
BA_5221	COG2011	ABC-type metal ion transport system permease component
BA_5222	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA_5225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA_5226	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BA_5229	COG1393	Belongs to the ArsC family
BA_5240	COG0039	L-malate dehydrogenase activity
BA_5244	COG1309	transcriptional regulator
BA_5245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA_5246	COG1960	acyl-CoA dehydrogenase activity
BA_5248	COG0183	Belongs to the thiolase family
BA_5249	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA_5249	COG1024	Enoyl-CoA hydratase
BA_5252	COG1686	Belongs to the peptidase S11 family
BA_5255	COG0011	TIGRFAM Protein of
BA_5256	COG0840	transmembrane signaling receptor activity
BA_5260	COG2814	Major facilitator Superfamily
BA_5261	COG0531	amino acid
BA_5263	COG0706	membrane insertase activity
BA_5265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BA_5272	COG0586	Pfam SNARE associated Golgi protein
BA_5274	COG1376	ErfK ybiS ycfS ynhG family protein
BA_5275	COG0745	RESPONSE REGULATOR receiver
BA_5276	COG5002	protein histidine kinase activity
BA_5278	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA_5281	COG2151	metal-sulfur cluster biosynthetic enzyme
BA_5282	COG3227	Zinc metalloprotease (Elastase)
BA_5283	COG1741	Belongs to the pirin family
BA_5286	COG0475	glutathione-regulated potassium exporter activity
BA_5287	COG0490	domain, Protein
BA_5289	COG1115	amino acid carrier protein
BA_5290	COG0783	Belongs to the Dps family
BA_5294	COG1611	Belongs to the LOG family
BA_5298	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_5299	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_5300	COG1115	amino acid carrier protein
BA_5301	COG1115	amino acid carrier protein
BA_5302	COG2910	NAD(P)H-binding
BA_5308	COG0656	L-ascorbic acid biosynthetic process
BA_5309	COG2814	Major facilitator Superfamily
BA_5311	COG1733	regulation of RNA biosynthetic process
BA_5313	COG1252	NADH dehydrogenase
BA_5314	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BA_5315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA_5317	COG0840	transmembrane signaling receptor activity
BA_5317	COG3290	protein histidine kinase activity
BA_5319	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BA_5320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BA_5323	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA_5324	COG3223	Belongs to the PsiE family
BA_5334	COG0557	exoribonuclease II activity
BA_5335	COG1647	Serine aminopeptidase, S33
BA_5336	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA_5358	COG4695	Portal protein
BA_5363	COG4974	Belongs to the 'phage' integrase family
BA_5365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BA_5366	COG0149	triose-phosphate isomerase activity
BA_5369	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA_5372	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BA_5376	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA_5379	COG2323	membrane
BA_5380	COG0740	serine-type endopeptidase activity
BA_5381	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA_5383	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BA_5385	COG1051	belongs to the nudix hydrolase family
BA_5387	COG0492	ferredoxin-NADP+ reductase activity
BA_5388	COG0457	Tetratricopeptide repeat
BA_5389	COG0110	maltose O-acetyltransferase activity
BA_5393	COG1950	PFAM Membrane protein of
BA_5395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA_5396	COG0556	nucleotide-excision repair
BA_5400	COG0789	Transcriptional regulator
BA_5405	COG2855	membrane
BA_5406	COG0583	DNA-binding transcription factor activity
BA_5408	COG0655	NAD(P)H dehydrogenase (quinone) activity
BA_5411	COG1132	(ABC) transporter
BA_5412	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA_5414	COG0793	Belongs to the peptidase S41A family
BA_5414	COG3409	Peptidoglycan-binding domain 1 protein
BA_5415	COG2177	Part of the ABC transporter FtsEX involved in
BA_5416	COG2884	Cell division ATP-binding protein ftsE
BA_5421	COG0653	protein targeting
BA_5422	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA_5424	COG1278	Cold shock
BA_5425	COG1040	competence protein
BA_5426	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BA_5427	COG0791	NLP P60 protein
BA_5427	COG1388	LysM domain
BA_5428	COG1733	regulation of RNA biosynthetic process
BA_5430	COG1307	EDD domain protein, DegV family
BA_5431	COG1739	Uncharacterized protein family UPF0029
BA_5432	COG1316	TRANSCRIPTIONal
BA_5433	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BA_5434	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BA_5435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA_5437	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BA_5437	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BA_5440	COG3394	polysaccharide catabolic process
BA_5441	COG1486	melibiose metabolic process
BA_5442	COG1447	Phosphotransferase system cellobiose-specific component IIA
BA_5443	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BA_5445	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BA_5446	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BA_5447	COG1447	Phosphotransferase system cellobiose-specific component IIA
BA_5449	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BA_5450	COG1301	dicarboxylic acid transport
BA_5452	COG0346	lactoylglutathione lyase activity
BA_5453	COG1511	domain protein
BA_5454	COG0583	DNA-binding transcription factor activity
BA_5455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BA_5460	COG1271	oxidase subunit
BA_5461	COG1294	oxidase, subunit
BA_5462	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BA_5464	COG1620	l-lactate permease
BA_5467	COG2389	metal-binding protein
BA_5470	COG1368	sulfuric ester hydrolase activity
BA_5475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA_5479	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA_5481	COG1388	LysM domain
BA_5481	COG3584	3D domain protein
BA_5486	COG4715	Zinc finger, swim domain protein
BA_5487	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA_5493	COG1191	sigma factor activity
BA_5495	COG0577	efflux transmembrane transporter activity
BA_5496	COG1136	(ABC) transporter
BA_5503	COG5002	protein histidine kinase activity
BA_5504	COG0745	RESPONSE REGULATOR receiver
BA_5505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BA_5509	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BA_5510	COG1134	teichoic acid transport
BA_5511	COG1682	transport, permease protein
BA_5512	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BA_5521	COG1609	Transcriptional regulator
BA_5524	COG0739	heme binding
BA_5528	COG2385	sporulation resulting in formation of a cellular spore
BA_5529	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA_5531	COG4836	Membrane
BA_5532	COG1007	ATP synthesis coupled electron transport
BA_5533	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA_5534	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BA_5536	COG0839	Belongs to the complex I subunit 6 family
BA_5539	COG0649	NAD binding
BA_5540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA_5542	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BA_5543	COG5001	Diguanylate cyclase
BA_5543	COG3300	MHYT domain
BA_5553	COG0356	it plays a direct role in the translocation of protons across the membrane
BA_5560	COG0698	ribose 5-phosphate isomerase
BA_5563	COG2190	(PTS) system
BA_5564	COG2259	Doxx family
BA_5565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BA_5568	COG0009	L-threonylcarbamoyladenylate synthase
BA_5571	COG2890	protein-(glutamine-N5) methyltransferase activity
BA_5572	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BA_5575	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BA_5576	COG1494	fructose-1,6-bisphosphatase
BA_5578	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA_5582	COG4821	SIS domain
BA_5584	COG3343	RNA polymerase activity
BA_5586	COG1960	acyl-CoA dehydrogenase activity
BA_5587	COG1960	acyl-CoA dehydrogenase activity
BA_5588	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA_5589	COG0183	Belongs to the thiolase family
BA_5590	COG0247	lactate metabolic process
BA_5590	COG2181	nitrate reductase activity
BA_5591	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA_5593	COG3300	MHYT domain
BA_5593	COG5001	Diguanylate cyclase
BA_5597	COG2197	response regulator
BA_5598	COG4585	Histidine kinase
BA_5599	COG0842	Transport permease protein
BA_5600	COG1131	(ABC) transporter
BA_5601	COG0024	Methionine aminopeptidase
BA_5606	COG2234	aminopeptidase activity
BA_5610	COG1595	DNA-templated transcription, initiation
BA_5611	COG0018	arginyl-trna synthetase
BA_5612	COG4506	Protein conserved in bacteria
BA_5613	COG1619	proteins homologs of microcin C7 resistance protein MccF
BA_5617	COG0010	Belongs to the arginase family
BA_5619	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BA_5620	COG2814	Major facilitator Superfamily
BA_5621	COG0789	Transcriptional regulator
BA_5622	COG0584	glycerophosphoryl diester phosphodiesterase
BA_5623	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA_5625	COG1994	Peptidase M50
BA_5627	COG1078	dGTPase activity
BA_5628	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA_5629	COG1120	ATPase activity
BA_5630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA_5635	COG0095	Lipoate-protein ligase
BA_5636	COG0280	phosphate acetyltransferase
BA_5640	COG3773	Cell wall hydrolase
BA_5642	COG2363	Small membrane protein
BA_5645	COG2233	PERMEase
BA_5646	COG0561	phosphatase activity
BA_5647	COG2814	Major facilitator Superfamily
BA_5649	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BA_5650	COG1131	(ABC) transporter
BA_5651	COG2755	lipolytic protein G-D-S-L family
BA_5652	COG1609	Transcriptional regulator
BA_5654	COG0460	homoserine dehydrogenase
BA_5658	COG1011	Hydrolase
BA_5659	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA_5661	COG2197	response regulator
BA_5663	COG0351	phosphomethylpyrimidine kinase
BA_5664	COG3706	GGDEF domain
BA_5665	COG2879	small protein
BA_5666	COG1966	Carbon starvation protein
BA_5667	COG3279	Response regulator of the LytR AlgR family
BA_5668	COG0477	Major facilitator Superfamily
BA_5673	COG0840	transmembrane signaling receptor activity
BA_5675	COG1607	acyl-coa hydrolase
BA_5678	COG0488	(ABC) transporter
BA_5684	COG0463	Glycosyl transferase, family 2
BA_5685	COG1309	transcriptional regulator
BA_5686	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA_5687	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA_5687	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA_5688	COG0628	permease
BA_5691	COG3279	Response regulator of the LytR AlgR family
BA_5692	COG3275	phosphorelay sensor kinase activity
BA_5693	COG2814	Major facilitator Superfamily
BA_5694	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA_5695	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BA_5696	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA_5700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BA_5701	COG1272	protein, Hemolysin III
BA_5705	COG0516	GMP reductase activity
BA_5706	COG1164	Oligoendopeptidase f
BA_5710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA_5711	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BA_5712	COG4853	Protein conserved in bacteria
BA_5713	COG4863	YycH protein
BA_5714	COG5002	protein histidine kinase activity
BA_5715	COG0745	RESPONSE REGULATOR receiver
BA_5717	COG0305	Participates in initiation and elongation during chromosome replication
BA_5719	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BA_5720	COG4241	membrane
BA_5722	COG0629	single-stranded DNA binding
BA_5724	COG0012	GTP binding
BA_5725	COG4481	Protein conserved in bacteria
BA_5726	COG0668	transmembrane transport
BA_5729	COG1475	DNA binding
BA_5730	COG1192	Involved in chromosome partitioning
BA_5734	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BA_5735	COG1847	R3H domain protein
BA_5736	COG0706	membrane insertase activity
BA_5858	COG0544	peptidyl-prolyl cis-trans isomerase activity