locus-tag	class	description
KM400_00010	COG0592	DNA-directed DNA polymerase activity
KM400_00015	COG2501	S4 domain
KM400_00025	COG0187	DNA topoisomerase II activity
KM400_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM400_00065	COG0516	GMP reductase activity
KM400_00065	COG0517	IMP dehydrogenase activity
KM400_00070	COG1686	Belongs to the peptidase S11 family
KM400_00100	COG1428	Deoxynucleoside kinase
KM400_00105	COG1428	Deoxynucleoside kinase
KM400_00110	COG1335	isochorismatase
KM400_00115	COG0590	tRNA wobble adenosine to inosine editing
KM400_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM400_00180	COG1982	Orn Lys Arg decarboxylase major
KM400_00190	COG0470	DNA polymerase III
KM400_00195	COG1774	PSP1 C-terminal conserved region
KM400_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM400_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM400_00220	COG2002	toxin-antitoxin pair type II binding
KM400_00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM400_00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM400_00230	COG0084	hydrolase, TatD family'
KM400_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM400_00250	COG4466	Protein conserved in bacteria
KM400_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM400_00270	COG0251	oxidation-reduction process
KM400_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM400_00305	COG2002	toxin-antitoxin pair type II binding
KM400_00310	COG2244	polysaccharide biosynthetic process
KM400_00315	COG3956	TIGRFAM MazG family protein
KM400_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM400_00340	COG1098	S1 RNA binding domain
KM400_00355	COG2208	phosphoserine phosphatase activity
KM400_00360	COG0037	tRNA processing
KM400_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM400_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM400_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM400_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM400_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM400_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM400_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM400_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM400_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM400_00420	COG1396	sequence-specific DNA binding
KM400_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM400_00455	COG3880	PFAM UvrB UvrC protein
KM400_00465	COG0542	response to heat
KM400_00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM400_00480	COG4956	integral membrane protein (PIN domain superfamily)
KM400_00500	COG1045	serine acetyltransferase
KM400_00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM400_00520	COG3688	RNA-binding protein containing a PIN domain
KM400_00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM400_00540	COG0250	Participates in transcription elongation, termination and antitermination
KM400_00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM400_00565	COG2813	Specifically methylates the guanine in position
KM400_00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM400_00580	COG1358	cellular component organization or biogenesis
KM400_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM400_00710	COG0201	protein transport
KM400_00720	COG0024	Methionine aminopeptidase
KM400_00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM400_00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM400_00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM400_00795	COG0489	protein tyrosine kinase activity
KM400_00805	COG2194	sulfuric ester hydrolase activity
KM400_00810	COG0726	polysaccharide deacetylase
KM400_00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM400_00895	COG4856	YbbR-like protein
KM400_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM400_00915	COG0596	Alpha beta hydrolase
KM400_00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM400_00940	COG1506	peptidase
KM400_00940	COG0823	Involved in the tonB-independent uptake of proteins
KM400_00940	COG4946	Tricorn protease homolog
KM400_00975	COG2011	ABC-type metal ion transport system permease component
KM400_00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM400_00985	COG1464	Belongs to the NlpA lipoprotein family
KM400_00990	COG0604	alcohol dehydrogenase
KM400_01005	COG2271	Major facilitator Superfamily
KM400_01015	COG2814	Major facilitator Superfamily
KM400_01030	COG0601	transmembrane transport
KM400_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM400_01040	COG0444	Belongs to the ABC transporter superfamily
KM400_01045	COG4608	Belongs to the ABC transporter superfamily
KM400_01050	COG4166	transmembrane transport
KM400_01060	COG2207	Transcriptional regulator
KM400_01075	COG4166	transmembrane transport
KM400_01080	COG4166	transmembrane transport
KM400_01085	COG0656	L-ascorbic acid biosynthetic process
KM400_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM400_01105	COG4149	molybdate abc transporter
KM400_01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM400_01115	COG1910	domain protein
KM400_01125	COG0583	DNA-binding transcription factor activity
KM400_01130	COG0697	spore germination
KM400_01145	COG0204	Acyl-transferase
KM400_01155	COG1609	Transcriptional regulator
KM400_01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_01175	COG0084	hydrolase, TatD family'
KM400_01180	COG5298	Protein conserved in bacteria
KM400_01205	COG0488	(ABC) transporter
KM400_01220	COG0747	negative chemotaxis
KM400_01225	COG0601	transmembrane transport
KM400_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM400_01235	COG0444	Belongs to the ABC transporter superfamily
KM400_01240	COG4608	Belongs to the ABC transporter superfamily
KM400_01270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM400_01275	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM400_01285	COG2814	Major facilitator Superfamily
KM400_01295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM400_01305	COG4294	response to UV
KM400_01310	COG0705	Rhomboid family
KM400_01310	COG0457	Tetratricopeptide repeat
KM400_01320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM400_01325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM400_01330	COG0864	Transcriptional regulator
KM400_01335	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM400_01340	COG2183	response to ionizing radiation
KM400_01435	COG0802	atpase or kinase
KM400_01440	COG1214	PFAM Peptidase M22, glycoprotease
KM400_01445	COG0456	acetyltransferase
KM400_01455	COG0488	(ABC) transporter
KM400_01470	COG1266	CAAX protease self-immunity
KM400_01490	COG2252	PERMEase
KM400_01500	COG5002	protein histidine kinase activity
KM400_01520	COG1968	undecaprenyl-diphosphatase activity
KM400_01535	COG2205	protein histidine kinase activity
KM400_01540	COG0745	RESPONSE REGULATOR receiver
KM400_01560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM400_01565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM400_01570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM400_01580	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM400_01595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM400_01605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM400_01615	COG0151	Belongs to the GarS family
KM400_01640	COG0210	DNA helicase
KM400_01650	COG4851	CamS sex pheromone cAM373 precursor
KM400_01670	COG1335	isochorismatase
KM400_01675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM400_01680	COG2011	ABC-type metal ion transport system permease component
KM400_01685	COG1464	Belongs to the NlpA lipoprotein family
KM400_01705	COG1846	Transcriptional regulator
KM400_01730	COG1597	lipid kinase activity
KM400_01735	COG0546	phosphoglycolate phosphatase activity
KM400_01740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM400_01750	COG1012	belongs to the aldehyde dehydrogenase family
KM400_01755	COG2076	Multidrug Resistance protein
KM400_01760	COG2309	aminopeptidase activity
KM400_01775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_01780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM400_01785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM400_01795	COG4807	Protein conserved in bacteria
KM400_01820	COG1757	Na H antiporter
KM400_01825	COG1473	amidohydrolase
KM400_01840	COG0450	alkyl hydroperoxide reductase
KM400_01860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_01865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_01870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_01885	COG0166	Belongs to the GPI family
KM400_01920	COG5002	protein histidine kinase activity
KM400_01940	COG3541	Predicted nucleotidyltransferase
KM400_01945	COG2814	Major facilitator Superfamily
KM400_01950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM400_01950	COG0723	plastoquinol--plastocyanin reductase activity
KM400_01960	COG0765	amino acid transport
KM400_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM400_01975	COG0840	transmembrane signaling receptor activity
KM400_01980	COG0840	transmembrane signaling receptor activity
KM400_01985	COG0366	Alpha amylase catalytic
KM400_01990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_01990	COG1263	PTS System
KM400_01990	COG2190	(PTS) system
KM400_02020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM400_02035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM400_02045	COG1116	anion transmembrane transporter activity
KM400_02050	COG0488	(ABC) transporter
KM400_02095	COG2270	Major facilitator Superfamily
KM400_02110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM400_02125	COG2310	stress, protein
KM400_02130	COG2310	stress, protein
KM400_02135	COG2310	stress, protein
KM400_02140	COG0861	Integral membrane protein TerC family
KM400_02150	COG3853	Toxic anion resistance protein (TelA)
KM400_02165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM400_02175	COG1295	ribonuclease BN
KM400_02180	COG2217	Heavy metal translocating P-type atpase
KM400_02185	COG0697	spore germination
KM400_02205	COG0586	Pfam SNARE associated Golgi protein
KM400_02220	COG3871	stress protein (general stress protein 26)
KM400_02225	COG0387	Pfam Sodium calcium exchanger
KM400_02235	COG0535	radical SAM domain protein
KM400_02260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM400_02265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM400_02270	COG0582	viral genome integration into host DNA
KM400_02280	COG1396	sequence-specific DNA binding
KM400_02295	COG1396	sequence-specific DNA binding
KM400_02330	COG1484	DNA-dependent DNA replication
KM400_02560	COG0101	tRNA pseudouridine synthase activity
KM400_02570	COG3829	transcription factor binding
KM400_02580	COG0833	amino acid
KM400_02585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM400_02615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_02615	COG1263	PTS System
KM400_02620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM400_02635	COG0463	Glycosyl transferase, family 2
KM400_02650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM400_02650	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM400_02670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM400_02690	COG1228	amidohydrolase
KM400_02695	COG1090	epimerase
KM400_02725	COG1988	membrane-bound metal-dependent
KM400_02730	COG1194	a g-specific adenine glycosylase
KM400_02755	COG1132	(ABC) transporter
KM400_02760	COG4129	membrane
KM400_02765	COG0069	glutamate synthase activity
KM400_02765	COG0070	glutamate synthase
KM400_02765	COG0067	glutamate synthase
KM400_02775	COG4555	ABC transporter
KM400_02795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM400_02800	COG0735	belongs to the Fur family
KM400_02915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM400_02920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM400_02930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM400_02940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM400_02950	COG2766	serine protein kinase
KM400_02970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM400_02980	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM400_02985	COG2268	Band 7 protein
KM400_02995	COG3290	protein histidine kinase activity
KM400_03000	COG4565	transcriptional regulatory protein
KM400_03005	COG2851	Citrate transporter
KM400_03025	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM400_03030	COG3842	ATPase activity
KM400_03035	COG1175	transmembrane transport
KM400_03040	COG0395	ABC-type sugar transport system, permease component
KM400_03050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM400_03055	COG0745	RESPONSE REGULATOR receiver
KM400_03060	COG5002	protein histidine kinase activity
KM400_03070	COG4990	cell redox homeostasis
KM400_03080	COG3290	protein histidine kinase activity
KM400_03085	COG4565	transcriptional regulatory protein
KM400_03090	COG3493	citrate carrier protein
KM400_03095	COG0281	malic enzyme
KM400_03110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_03120	COG5002	protein histidine kinase activity
KM400_03125	COG0745	RESPONSE REGULATOR receiver
KM400_03130	COG0454	-acetyltransferase
KM400_03130	COG0456	acetyltransferase
KM400_03135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM400_03140	COG3383	formate dehydrogenase (NAD+) activity
KM400_03145	COG2427	Protein of unknown function (DUF1641)
KM400_03160	COG0531	amino acid
KM400_03165	COG0640	Transcriptional regulator
KM400_03170	COG2217	Heavy metal translocating P-type atpase
KM400_03175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM400_03190	COG3227	Zinc metalloprotease (Elastase)
KM400_03210	COG2720	vancomycin resistance protein
KM400_03215	COG1316	TRANSCRIPTIONal
KM400_03220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_03225	COG0346	lactoylglutathione lyase activity
KM400_03230	COG1253	flavin adenine dinucleotide binding
KM400_03235	COG1027	Aspartate ammonia-lyase
KM400_03240	COG1620	l-lactate permease
KM400_03255	COG3104	oligopeptide transport
KM400_03260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_03280	COG2226	methyltransferase
KM400_03285	COG0156	8-amino-7-oxononanoate synthase activity
KM400_03290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM400_03300	COG4548	von Willebrand factor, type A
KM400_03305	COG0714	Associated with various cellular activities
KM400_03310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM400_03330	COG0531	amino acid
KM400_03335	COG2188	Transcriptional regulator
KM400_03340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_03340	COG1263	PTS System
KM400_03345	COG0366	Alpha amylase catalytic
KM400_03360	COG0697	spore germination
KM400_03370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM400_03375	COG1115	amino acid carrier protein
KM400_03380	COG1126	abc transporter atp-binding protein
KM400_03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM400_03390	COG0765	amino acid transport
KM400_03395	COG0765	amino acid transport
KM400_03400	COG0833	amino acid
KM400_03425	COG2378	regulation of single-species biofilm formation
KM400_03430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM400_03435	COG5002	protein histidine kinase activity
KM400_03450	COG0659	secondary active sulfate transmembrane transporter activity
KM400_03465	COG0747	negative chemotaxis
KM400_03475	COG0601	transmembrane transport
KM400_03480	COG4608	Belongs to the ABC transporter superfamily
KM400_03490	COG2271	Major facilitator Superfamily
KM400_03495	COG1846	Transcriptional regulator
KM400_03505	COG1609	Transcriptional regulator
KM400_03510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM400_03525	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM400_03530	COG1879	ABC-type sugar transport system periplasmic component
KM400_03555	COG1063	alcohol dehydrogenase
KM400_03570	COG3568	Endonuclease Exonuclease Phosphatase
KM400_03595	COG1968	undecaprenyl-diphosphatase activity
KM400_03600	COG0840	transmembrane signaling receptor activity
KM400_03605	COG3584	3D domain protein
KM400_03605	COG1388	LysM domain
KM400_03610	COG1476	TRANSCRIPTIONal
KM400_03625	COG3104	oligopeptide transport
KM400_03630	COG1114	Component of the transport system for branched-chain amino acids
KM400_03645	COG1113	amino acid transport
KM400_03650	COG2252	PERMEase
KM400_03675	COG0569	domain protein
KM400_03675	COG0475	glutathione-regulated potassium exporter activity
KM400_03690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM400_03695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM400_03700	COG0833	amino acid
KM400_03705	COG4990	cell redox homeostasis
KM400_03720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM400_03725	COG0697	spore germination
KM400_03730	COG0531	amino acid
KM400_03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM400_03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM400_03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM400_03750	COG1918	ferrous iron import across plasma membrane
KM400_03755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM400_03760	COG0573	inorganic phosphate transmembrane transporter activity
KM400_03765	COG0581	inorganic phosphate transmembrane transporter activity
KM400_03775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM400_03895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM400_03915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM400_03920	COG1116	anion transmembrane transporter activity
KM400_03925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM400_03930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM400_03935	COG0352	thiamine-phosphate diphosphorylase activity
KM400_03940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM400_03945	COG2104	thiamine diphosphate biosynthetic process
KM400_03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM400_03960	COG0351	phosphomethylpyrimidine kinase
KM400_04000	COG2205	protein histidine kinase activity
KM400_04005	COG2814	Major facilitator Superfamily
KM400_04010	COG1846	Transcriptional regulator
KM400_04025	COG2252	PERMEase
KM400_04030	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_04035	COG1376	ErfK ybiS ycfS ynhG family protein
KM400_04045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM400_04050	COG1621	beta-fructofuranosidase activity
KM400_04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_04055	COG1263	PTS System
KM400_04060	COG1609	Transcriptional regulator
KM400_04070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM400_04110	COG0778	Nitroreductase
KM400_04115	COG2719	SpoVR family
KM400_04140	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM400_04145	COG1937	Protein conserved in bacteria
KM400_04150	COG0425	Belongs to the sulfur carrier protein TusA family
KM400_04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM400_04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM400_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_04160	COG0425	Belongs to the sulfur carrier protein TusA family
KM400_04165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM400_04175	COG2210	Belongs to the sulfur carrier protein TusA family
KM400_04180	COG0730	response to heat
KM400_04190	COG1316	TRANSCRIPTIONal
KM400_04195	COG0604	alcohol dehydrogenase
KM400_04200	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM400_04215	COG3711	transcriptional antiterminator
KM400_04215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM400_04220	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM400_04225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM400_04245	COG1388	LysM domain
KM400_04245	COG3584	3D domain protein
KM400_04250	COG0577	efflux transmembrane transporter activity
KM400_04255	COG1136	(ABC) transporter
KM400_04265	COG5522	Integral membrane protein (intg_mem_TP0381)
KM400_04280	COG1114	Component of the transport system for branched-chain amino acids
KM400_04285	COG3546	catalase activity
KM400_04320	COG0586	Pfam SNARE associated Golgi protein
KM400_04355	COG0531	amino acid
KM400_04360	COG0475	glutathione-regulated potassium exporter activity
KM400_04370	COG1737	Transcriptional regulator
KM400_04380	COG1263	PTS System
KM400_04380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_04390	COG2259	Doxx family
KM400_04405	COG0697	spore germination
KM400_04410	COG1522	sequence-specific DNA binding
KM400_04425	COG2076	Multidrug Resistance protein
KM400_04430	COG1309	transcriptional regulator
KM400_04435	COG2814	Major facilitator Superfamily
KM400_04440	COG1733	regulation of RNA biosynthetic process
KM400_04450	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM400_04455	COG4533	DNA binding
KM400_04460	COG2211	Major facilitator Superfamily
KM400_04470	COG0693	protein deglycase activity
KM400_04475	COG0753	catalase activity
KM400_04475	COG0693	protein deglycase activity
KM400_04485	COG0531	amino acid
KM400_04490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM400_04500	COG1012	belongs to the aldehyde dehydrogenase family
KM400_04505	COG1132	(ABC) transporter
KM400_04515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM400_04520	COG0765	amino acid transport
KM400_04525	COG1126	abc transporter atp-binding protein
KM400_04540	COG0189	ligase activity
KM400_04570	COG0028	Belongs to the TPP enzyme family
KM400_04575	COG3527	Alpha-acetolactate decarboxylase
KM400_04590	COG0561	phosphatase activity
KM400_04605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM400_04620	COG0659	secondary active sulfate transmembrane transporter activity
KM400_04640	COG0653	protein targeting
KM400_04645	COG2244	polysaccharide biosynthetic process
KM400_04655	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM400_04660	COG4196	transglutaminase domain protein
KM400_04675	COG1696	Membrane protein involved in D-alanine export
KM400_04690	COG1024	Enoyl-CoA hydratase
KM400_04705	COG1363	Peptidase, m42
KM400_04725	COG3938	Belongs to the proline racemase family
KM400_04765	COG0601	transmembrane transport
KM400_04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM400_04780	COG4608	Belongs to the ABC transporter superfamily
KM400_04785	COG0322	excinuclease ABC activity
KM400_04815	COG0477	Major facilitator Superfamily
KM400_04820	COG3290	protein histidine kinase activity
KM400_04825	COG4565	transcriptional regulatory protein
KM400_04830	COG3181	Tripartite tricarboxylate transporter family receptor
KM400_04860	COG0789	Transcriptional regulator
KM400_04860	COG4978	Transcriptional regulator
KM400_04875	COG0305	Participates in initiation and elongation during chromosome replication
KM400_04915	COG0477	Major facilitator Superfamily
KM400_04965	COG1309	transcriptional regulator
KM400_04985	COG1183	phosphatidylcholine synthase activity
KM400_05005	COG2376	Dihydroxyacetone kinase
KM400_05015	COG2376	Dihydroxyacetone kinase
KM400_05020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM400_05025	COG1959	2 iron, 2 sulfur cluster binding
KM400_05055	COG2770	Histidine kinase
KM400_05055	COG3437	response regulator, receiver
KM400_05105	COG3237	CsbD-like
KM400_05130	COG1191	sigma factor activity
KM400_05140	COG2208	phosphoserine phosphatase activity
KM400_05145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM400_05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM400_05150	COG0784	Response regulator, receiver
KM400_05150	COG2205	protein histidine kinase activity
KM400_05150	COG2198	Histidine kinase
KM400_05205	COG0420	3'-5' exonuclease activity
KM400_05210	COG4717	serine-type aminopeptidase activity
KM400_05230	COG1309	transcriptional regulator
KM400_05235	COG2814	Major facilitator Superfamily
KM400_05240	COG0346	lactoylglutathione lyase activity
KM400_05245	COG0346	lactoylglutathione lyase activity
KM400_05250	COG0457	Tetratricopeptide repeat
KM400_05255	COG2267	carboxylic ester hydrolase activity
KM400_05275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM400_05280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM400_05290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM400_05330	COG0477	Major facilitator Superfamily
KM400_05335	COG0477	Major facilitator Superfamily
KM400_05345	COG3973	AAA domain
KM400_05350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM400_05370	COG4980	gas vesicle protein
KM400_05375	COG0537	adenosine 5'-monophosphoramidase activity
KM400_05380	COG1131	(ABC) transporter
KM400_05385	COG4473	ABC transporter
KM400_05400	COG1309	transcriptional regulator
KM400_05410	COG3402	PFAM membrane-flanked domain
KM400_05455	COG3402	PFAM membrane-flanked domain
KM400_05460	COG3428	Bacterial PH domain
KM400_05465	COG2329	Antibiotic biosynthesis monooxygenase
KM400_05470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM400_05475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM400_05480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM400_05485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM400_05520	COG1309	transcriptional regulator
KM400_05525	COG1511	domain protein
KM400_05550	COG1609	Transcriptional regulator
KM400_05560	COG1234	tRNA 3'-trailer cleavage
KM400_05565	COG0095	Lipoate-protein ligase
KM400_05575	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_05605	COG3209	COG3209 Rhs family protein
KM400_05645	COG1078	dGTPase activity
KM400_05655	COG1595	DNA-templated transcription, initiation
KM400_05660	COG3708	Transcriptional regulator
KM400_05660	COG2207	Transcriptional regulator
KM400_05675	COG2205	protein histidine kinase activity
KM400_05680	COG0745	RESPONSE REGULATOR receiver
KM400_05705	COG0501	Belongs to the peptidase M48B family
KM400_05710	COG0840	transmembrane signaling receptor activity
KM400_05715	COG0697	spore germination
KM400_05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM400_05740	COG2224	Isocitrate lyase
KM400_05765	COG4903	ComK protein
KM400_05770	COG0398	Pfam SNARE associated Golgi protein
KM400_05780	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM400_05785	COG1074	ATP-dependent DNA helicase activity
KM400_05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM400_05855	COG0367	asparagine synthase
KM400_05860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM400_05865	COG0753	catalase activity
KM400_05870	COG0004	ammonium transporteR
KM400_05890	COG2996	Protein conserved in bacteria
KM400_05900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM400_05910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_05925	COG0561	phosphatase activity
KM400_05935	COG0542	response to heat
KM400_05945	COG2267	carboxylic ester hydrolase activity
KM400_05960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_05965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM400_05970	COG5504	Zn-dependent protease
KM400_05980	COG0180	Tryptophanyl-tRNA synthetase
KM400_05990	COG4166	transmembrane transport
KM400_05995	COG0601	transmembrane transport
KM400_06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM400_06005	COG0444	Belongs to the ABC transporter superfamily
KM400_06010	COG4608	Belongs to the ABC transporter superfamily
KM400_06015	COG0534	Mate efflux family protein
KM400_06020	COG4166	transmembrane transport
KM400_06035	COG0861	Integral membrane protein TerC family
KM400_06040	COG4862	establishment of competence for transformation
KM400_06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM400_06055	COG1164	Oligoendopeptidase f
KM400_06065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM400_06070	COG2346	COG2346, Truncated hemoglobins
KM400_06075	COG4116	CYTH
KM400_06085	COG2357	RelA SpoT domain protein
KM400_06095	COG0564	pseudouridine synthase activity
KM400_06115	COG0463	Glycosyl transferase, family 2
KM400_06115	COG1216	Glycosyl transferase, family 2
KM400_06155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM400_06170	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM400_06215	COG2153	protein acetylation
KM400_06225	COG2382	esterase
KM400_06240	COG5492	domain, Protein
KM400_06245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM400_06255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM400_06255	COG0512	Glutamine amidotransferase of anthranilate synthase
KM400_06290	COG1620	l-lactate permease
KM400_06295	COG5634	Uncharacterized conserved protein (DUF2278)
KM400_06350	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM400_06360	COG1476	TRANSCRIPTIONal
KM400_06420	COG2226	methyltransferase
KM400_06430	COG1686	Belongs to the peptidase S11 family
KM400_06435	COG0681	Belongs to the peptidase S26 family
KM400_06470	COG1012	belongs to the aldehyde dehydrogenase family
KM400_06475	COG3842	ATPase activity
KM400_06480	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM400_06485	COG1177	transmembrane transport
KM400_06490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM400_06500	COG2409	Drug exporters of the RND superfamily
KM400_06510	COG0564	pseudouridine synthase activity
KM400_06520	COG2340	Cysteine-rich secretory protein family
KM400_06525	COG0247	lactate metabolic process
KM400_06530	COG0277	FAD linked oxidase domain protein
KM400_06535	COG3835	regulator
KM400_06545	COG0745	RESPONSE REGULATOR receiver
KM400_06550	COG5002	protein histidine kinase activity
KM400_06555	COG2186	Transcriptional regulator
KM400_06575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM400_06585	COG2116	formate transmembrane transporter activity
KM400_06590	COG0861	Integral membrane protein TerC family
KM400_06605	COG2030	dehydratase
KM400_06625	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_06630	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM400_06635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM400_06640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM400_06655	COG1840	ABC-type Fe3 transport system, periplasmic component
KM400_06685	COG1349	DNA-binding transcription factor activity
KM400_06705	COG2861	carbohydrate metabolic process
KM400_06715	COG3852	Histidine kinase
KM400_06720	COG1846	Transcriptional regulator
KM400_06730	COG2318	DinB family
KM400_06735	COG5002	protein histidine kinase activity
KM400_06745	COG0720	synthase
KM400_06760	COG4873	Protein conserved in bacteria
KM400_06790	COG1780	Probably involved in ribonucleotide reductase function
KM400_06810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM400_06815	COG1725	Transcriptional regulator
KM400_06820	COG1131	(ABC) transporter
KM400_06830	COG1131	(ABC) transporter
KM400_06835	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM400_06850	COG1522	sequence-specific DNA binding
KM400_06860	COG1335	isochorismatase
KM400_06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM400_06875	COG2070	2-Nitropropane dioxygenase
KM400_06880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM400_06890	COG1696	Membrane protein involved in D-alanine export
KM400_06915	COG0716	FMN binding
KM400_06930	COG3173	Aminoglycoside phosphotransferase
KM400_06950	COG0534	Mate efflux family protein
KM400_06955	COG1968	undecaprenyl-diphosphatase activity
KM400_06970	COG1846	Transcriptional regulator
KM400_06980	COG1301	dicarboxylic acid transport
KM400_06990	COG4709	membrane
KM400_06995	COG3874	Sporulation protein YtfJ
KM400_07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM400_07025	COG0028	Belongs to the TPP enzyme family
KM400_07030	COG0440	acetolactate synthase activity
KM400_07035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM400_07045	COG0473	3-isopropylmalate dehydrogenase activity
KM400_07070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM400_07105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM400_07120	COG1183	phosphatidylcholine synthase activity
KM400_07125	COG1368	sulfuric ester hydrolase activity
KM400_07135	COG0019	diaminopimelate decarboxylase activity
KM400_07155	COG0529	Catalyzes the synthesis of activated sulfate
KM400_07160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM400_07185	COG0733	neurotransmitter:sodium symporter activity
KM400_07205	COG1757	Na H antiporter
KM400_07220	COG4758	membrane
KM400_07225	COG4585	Histidine kinase
KM400_07230	COG2197	response regulator
KM400_07240	COG1114	Component of the transport system for branched-chain amino acids
KM400_07250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM400_07275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM400_07275	COG1017	nitric oxide dioxygenase activity
KM400_07290	COG0730	response to heat
KM400_07295	COG0306	phosphate transporter
KM400_07300	COG1392	Phosphate transport regulator
KM400_07305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM400_07325	COG1801	Protein of unknown function DUF72
KM400_07335	COG0582	viral genome integration into host DNA
KM400_07340	COG5002	protein histidine kinase activity
KM400_07360	COG0392	lysyltransferase activity
KM400_07360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM400_07375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM400_07380	COG1686	Belongs to the peptidase S11 family
KM400_07385	COG2715	membrane protein required for spore maturation
KM400_07390	COG0700	Nucleoside recognition
KM400_07395	COG1187	pseudouridine synthase activity
KM400_07405	COG1333	cytochrome c biogenesis protein
KM400_07410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM400_07415	COG0745	RESPONSE REGULATOR receiver
KM400_07420	COG5002	protein histidine kinase activity
KM400_07425	COG2096	Adenosyltransferase
KM400_07440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM400_07445	COG1141	Ferredoxin
KM400_07450	COG4955	Helix-turn-helix domain
KM400_07455	COG0514	ATP-dependent DNA helicase (RecQ)
KM400_07460	COG1266	CAAX protease self-immunity
KM400_07480	COG4862	establishment of competence for transformation
KM400_07485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM400_07505	COG0492	ferredoxin-NADP+ reductase activity
KM400_07580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM400_07595	COG0142	geranyltranstransferase activity
KM400_07605	COG0142	geranyltranstransferase activity
KM400_07625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM400_07630	COG0457	Tetratricopeptide repeat
KM400_07650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM400_07660	COG4347	Protein of unknown function (DUF1405)
KM400_07675	COG2738	Putative neutral zinc metallopeptidase
KM400_07685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_07690	COG1694	Mazg nucleotide pyrophosphohydrolase
KM400_07705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM400_07710	COG0438	transferase activity, transferring glycosyl groups
KM400_07765	COG3935	DnaD domain protein
KM400_07770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM400_07780	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM400_07780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM400_07840	COG0116	Belongs to the methyltransferase superfamily
KM400_07850	COG1199	ATP-dependent helicase activity
KM400_07855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM400_07865	COG3173	Aminoglycoside phosphotransferase
KM400_07870	COG0024	Methionine aminopeptidase
KM400_07880	COG2233	PERMEase
KM400_07885	COG2311	Membrane
KM400_07890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM400_07900	COG0456	acetyltransferase
KM400_07950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM400_07975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM400_07990	COG1215	transferase activity, transferring glycosyl groups
KM400_08010	COG0454	-acetyltransferase
KM400_08030	COG0328	RNA-DNA hybrid ribonuclease activity
KM400_08070	COG1280	lysine exporter protein (LysE YggA)
KM400_08085	COG3162	membrane
KM400_08090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM400_08095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM400_08105	COG0475	glutathione-regulated potassium exporter activity
KM400_08110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM400_08115	COG4978	Transcriptional regulator
KM400_08115	COG0789	Transcriptional regulator
KM400_08125	COG2323	membrane
KM400_08130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM400_08185	COG1923	regulation of RNA biosynthetic process
KM400_08195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM400_08200	COG1360	Flagellar Motor Protein
KM400_08205	COG2201	protein-glutamate methylesterase activity
KM400_08210	COG0643	Histidine kinase
KM400_08210	COG2198	Histidine kinase
KM400_08215	COG2198	Histidine kinase
KM400_08215	COG0643	Histidine kinase
KM400_08220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM400_08220	COG1776	CheC inhibitor of MCP methylation
KM400_08235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM400_08255	COG1256	bacterial-type flagellum assembly
KM400_08280	COG1815	bacterial-type flagellum-dependent cell motility
KM400_08285	COG1558	bacterial-type flagellum-dependent cell motility
KM400_08300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM400_08310	COG1157	protein secretion by the type III secretion system
KM400_08350	COG0784	Response regulator, receiver
KM400_08350	COG0835	chemotaxis
KM400_08360	COG0463	Glycosyl transferase, family 2
KM400_08400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM400_08405	COG0741	lytic transglycosylase activity
KM400_08420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM400_08420	COG1776	CheC inhibitor of MCP methylation
KM400_08430	COG1338	Plays a role in the flagellum-specific transport system
KM400_08435	COG1987	bacterial-type flagellum assembly
KM400_08445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM400_08450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM400_08455	COG1419	protein localization to endoplasmic reticulum
KM400_08460	COG4786	Flagellar basal body rod
KM400_08465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM400_08490	COG1309	transcriptional regulator
KM400_08510	COG2329	Antibiotic biosynthesis monooxygenase
KM400_08540	COG3842	ATPase activity
KM400_08545	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM400_08555	COG1234	tRNA 3'-trailer cleavage
KM400_08580	COG1686	Belongs to the peptidase S11 family
KM400_08590	COG0406	alpha-ribazole phosphatase activity
KM400_08620	COG0367	asparagine synthase
KM400_08650	COG1802	Transcriptional regulator
KM400_08655	COG0697	spore germination
KM400_08660	COG0523	cobalamin synthesis protein
KM400_08665	COG0701	Predicted permease
KM400_08675	COG0438	transferase activity, transferring glycosyl groups
KM400_08675	COG1216	Glycosyl transferase, family 2
KM400_08680	COG1757	Na H antiporter
KM400_08685	COG0114	fumarate hydratase activity
KM400_08710	COG3340	Belongs to the peptidase S51 family
KM400_08730	COG0785	Cytochrome C biogenesis protein
KM400_08760	COG2733	membrane
KM400_08795	COG1131	(ABC) transporter
KM400_08810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM400_08815	COG0528	UMP kinase activity
KM400_08825	COG1027	Aspartate ammonia-lyase
KM400_08830	COG0281	malic enzyme
KM400_08835	COG4191	Histidine kinase
KM400_08840	COG0784	Response regulator, receiver
KM400_08845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM400_08905	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM400_08915	COG2814	Major facilitator Superfamily
KM400_08930	COG1966	Carbon starvation protein
KM400_08940	COG0477	Major facilitator Superfamily
KM400_08945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_08955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM400_08970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM400_08985	COG2244	polysaccharide biosynthetic process
KM400_08990	COG0733	neurotransmitter:sodium symporter activity
KM400_09000	COG5566	PFAM Mor transcription activator
KM400_09005	COG2323	membrane
KM400_09020	COG2084	Dehydrogenase
KM400_09035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM400_09045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM400_09050	COG0028	Belongs to the TPP enzyme family
KM400_09055	COG0440	acetolactate synthase activity
KM400_09060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM400_09070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM400_09100	COG3384	dioxygenase
KM400_09110	COG3279	Response regulator of the LytR AlgR family
KM400_09115	COG0427	acetyl-CoA hydrolase
KM400_09135	COG1073	alpha beta
KM400_09140	COG4166	transmembrane transport
KM400_09165	COG0535	radical SAM domain protein
KM400_09170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_09190	COG1914	H( )-stimulated, divalent metal cation uptake system
KM400_09205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM400_09235	COG2390	Transcriptional regulator
KM400_09245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_09250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM400_09265	COG4224	UPF0291 protein
KM400_09285	COG0006	proline dipeptidase activity
KM400_09290	COG2132	Multicopper oxidase
KM400_09305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM400_09320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM400_09335	COG2372	response to copper ion
KM400_09335	COG1276	copper resistance
KM400_09340	COG4549	nuclear export factor GLE1
KM400_09350	COG0697	spore germination
KM400_09355	COG0583	DNA-binding transcription factor activity
KM400_09360	COG1959	2 iron, 2 sulfur cluster binding
KM400_09365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM400_09370	COG0778	Nitroreductase
KM400_09380	COG0628	permease
KM400_09390	COG1231	oxidoreductase activity
KM400_09395	COG0523	cobalamin synthesis protein
KM400_09410	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_09415	COG2030	dehydratase
KM400_09420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_09430	COG0411	ABC transporter
KM400_09450	COG0583	DNA-binding transcription factor activity
KM400_09460	COG1942	4-Oxalocrotonate Tautomerase
KM400_09470	COG1846	Transcriptional regulator
KM400_09480	COG1271	oxidase subunit
KM400_09485	COG1294	oxidase, subunit
KM400_09490	COG4988	ABC transporter
KM400_09495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM400_09515	COG1686	Belongs to the peptidase S11 family
KM400_09530	COG1388	LysM domain
KM400_09530	COG0791	NLP P60 protein
KM400_09545	COG0745	RESPONSE REGULATOR receiver
KM400_09560	COG0300	oxidoreductase activity
KM400_09595	COG0460	homoserine dehydrogenase
KM400_09620	COG1316	TRANSCRIPTIONal
KM400_09630	COG0745	RESPONSE REGULATOR receiver
KM400_09635	COG5002	protein histidine kinase activity
KM400_09650	COG1285	pathogenesis
KM400_09655	COG1247	-acetyltransferase
KM400_09675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM400_09685	COG1082	Xylose isomerase domain protein TIM barrel
KM400_09695	COG2814	Major facilitator Superfamily
KM400_09700	COG1279	arginine transmembrane transporter activity
KM400_09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM400_09745	COG0577	efflux transmembrane transporter activity
KM400_09750	COG2002	toxin-antitoxin pair type II binding
KM400_09755	COG1404	Belongs to the peptidase S8 family
KM400_09760	COG0640	Transcriptional regulator
KM400_09765	COG0667	Aldo Keto reductase
KM400_09795	COG0840	transmembrane signaling receptor activity
KM400_09810	COG3949	Membrane
KM400_09815	COG0783	Belongs to the Dps family
KM400_09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM400_09840	COG1231	oxidoreductase activity
KM400_09850	COG4989	oxidoreductase activity
KM400_09855	COG0523	cobalamin synthesis protein
KM400_09860	COG0456	acetyltransferase
KM400_09915	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM400_09915	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM400_09925	COG0702	epimerase
KM400_09935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM400_09945	COG4166	transmembrane transport
KM400_09960	COG0406	alpha-ribazole phosphatase activity
KM400_09970	COG5337	Spore coat protein CotH
KM400_09975	COG1051	belongs to the nudix hydrolase family
KM400_09980	COG0586	Pfam SNARE associated Golgi protein
KM400_09985	COG2244	polysaccharide biosynthetic process
KM400_09995	COG0701	Predicted permease
KM400_10000	COG3689	TIGRFAM TIGR03943 family protein
KM400_10005	COG1607	acyl-coa hydrolase
KM400_10015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM400_10030	COG0702	epimerase
KM400_10035	COG2839	Protein conserved in bacteria
KM400_10040	COG1253	flavin adenine dinucleotide binding
KM400_10055	COG1114	Component of the transport system for branched-chain amino acids
KM400_10060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM400_10080	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM400_10090	COG1876	peptidase activity
KM400_10100	COG0154	amidase activity
KM400_10105	COG2211	Major facilitator Superfamily
KM400_10125	COG0561	phosphatase activity
KM400_10135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM400_10140	COG4106	trans-aconitate 2-methyltransferase activity
KM400_10155	COG1819	glycosyl
KM400_10160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_10165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_10190	COG0456	acetyltransferase
KM400_10240	COG3874	Sporulation protein YtfJ
KM400_10265	COG2226	methyltransferase
KM400_10290	COG0346	lactoylglutathione lyase activity
KM400_10300	COG0604	alcohol dehydrogenase
KM400_10305	COG1595	DNA-templated transcription, initiation
KM400_10330	COG0386	Belongs to the glutathione peroxidase family
KM400_10335	COG1305	Transglutaminase-like
KM400_10340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM400_10345	COG0714	Associated with various cellular activities
KM400_10360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM400_10365	COG1140	nitrate reductase beta subunit
KM400_10370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM400_10375	COG2181	nitrate reductase activity
KM400_10395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM400_10400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM400_10405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM400_10410	COG0303	'Molybdopterin
KM400_10415	COG0314	molybdopterin synthase activity
KM400_10425	COG2223	nitrite transmembrane transporter activity
KM400_10440	COG1648	precorrin-2 dehydrogenase activity
KM400_10450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM400_10450	COG1587	Uroporphyrinogen-III synthase
KM400_10455	COG2146	nitrite reductase [NAD(P)H] activity
KM400_10460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM400_10465	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM400_10500	COG2359	stage V sporulation protein S
KM400_10515	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM400_10530	COG1418	mRNA catabolic process
KM400_10535	COG0488	(ABC) transporter
KM400_10550	COG0629	single-stranded DNA binding
KM400_10565	COG1413	lyase activity
KM400_10580	COG2136	Putative SAM-dependent methyltransferase
KM400_10580	COG2521	methyltransferase
KM400_10585	COG0018	arginyl-trna synthetase
KM400_10610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM400_10630	COG0017	Asparaginyl-tRNA synthetase
KM400_10650	COG1674	ftsk spoiiie
KM400_10720	COG1929	Belongs to the glycerate kinase type-1 family
KM400_10725	COG0471	metal ion transport
KM400_10730	COG0745	RESPONSE REGULATOR receiver
KM400_10735	COG3850	Histidine kinase
KM400_10735	COG5002	protein histidine kinase activity
KM400_10750	COG0733	neurotransmitter:sodium symporter activity
KM400_10775	COG2610	gluconate transmembrane transporter activity
KM400_10780	COG1454	alcohol dehydrogenase
KM400_10785	COG1794	racemase activity, acting on amino acids and derivatives
KM400_10795	COG0456	acetyltransferase
KM400_10810	COG1131	(ABC) transporter
KM400_10825	COG0546	phosphoglycolate phosphatase activity
KM400_10845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM400_10860	COG0768	penicillin binding
KM400_10865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM400_10870	COG0204	Acyl-transferase
KM400_10875	COG1272	protein, Hemolysin III
KM400_10885	COG0805	protein transport
KM400_10895	COG1307	EDD domain protein, DegV family
KM400_10900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM400_10905	COG1999	signal sequence binding
KM400_10910	COG0071	Belongs to the small heat shock protein (HSP20) family
KM400_10915	COG0367	asparagine synthase
KM400_10930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_10935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM400_10960	COG1051	belongs to the nudix hydrolase family
KM400_10970	COG0668	transmembrane transport
KM400_10975	COG4585	Histidine kinase
KM400_10975	COG2203	Gaf domain
KM400_10980	COG2197	response regulator
KM400_10990	COG1064	alcohol dehydrogenase
KM400_11015	COG1070	Carbohydrate kinase
KM400_11020	COG1070	Carbohydrate kinase
KM400_11050	COG1125	glycine betaine transport
KM400_11050	COG0517	IMP dehydrogenase activity
KM400_11055	COG1174	glycine betaine transport
KM400_11090	COG1253	flavin adenine dinucleotide binding
KM400_11095	COG1012	belongs to the aldehyde dehydrogenase family
KM400_11100	COG5506	Protein of unknown function (DUF1694)
KM400_11115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM400_11120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM400_11125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM400_11130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM400_11135	COG0456	acetyltransferase
KM400_11140	COG3829	transcription factor binding
KM400_11145	COG1509	lysine 2,3-aminomutase activity
KM400_11185	COG4326	sporulation control protein
KM400_11190	COG0671	phosphoesterase, PA-phosphatase related
KM400_11195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM400_11200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM400_11230	COG1715	Restriction endonuclease
KM400_11230	COG1787	Restriction endonuclease
KM400_11320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM400_11360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM400_11360	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM400_11365	COG2814	Major facilitator Superfamily
KM400_11370	COG4841	protein insertion into membrane
KM400_11375	COG0372	Belongs to the citrate synthase family
KM400_11380	COG2079	MmgE PrpD family protein
KM400_11385	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM400_11390	COG1960	acyl-CoA dehydrogenase activity
KM400_11395	COG2084	Dehydrogenase
KM400_11405	COG1280	lysine exporter protein (LysE YggA)
KM400_11410	COG1024	Enoyl-CoA hydratase
KM400_11425	COG0420	3'-5' exonuclease activity
KM400_11430	COG0419	ATPase involved in DNA repair
KM400_11455	COG2223	nitrite transmembrane transporter activity
KM400_11460	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_11465	COG1169	isochorismate synthase
KM400_11470	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM400_11475	COG1535	isochorismatase
KM400_11475	COG3433	isochorismatase activity
KM400_11485	COG3251	PFAM MbtH domain protein
KM400_11490	COG2814	Major facilitator Superfamily
KM400_11505	COG0776	regulation of translation
KM400_11515	COG2318	DinB family
KM400_11540	COG2329	Antibiotic biosynthesis monooxygenase
KM400_11545	COG1187	pseudouridine synthase activity
KM400_11550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM400_11565	COG0596	Alpha beta hydrolase
KM400_11570	COG2814	Major facilitator Superfamily
KM400_11595	COG2226	methyltransferase
KM400_11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_11675	COG1247	-acetyltransferase
KM400_11705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM400_11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_11725	COG1278	Cold shock
KM400_11740	COG0010	Belongs to the arginase family
KM400_11745	COG0561	phosphatase activity
KM400_11790	COG0583	DNA-binding transcription factor activity
KM400_11795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM400_11810	COG0583	DNA-binding transcription factor activity
KM400_11815	COG2258	MOSC domain
KM400_11830	COG1132	(ABC) transporter
KM400_11835	COG1132	(ABC) transporter
KM400_11855	COG1396	sequence-specific DNA binding
KM400_11880	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM400_11885	COG1595	DNA-templated transcription, initiation
KM400_11910	COG1649	PFAM Uncharacterised BCR, COG1649
KM400_11935	COG2971	BadF BadG BcrA BcrD
KM400_11940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM400_11945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM400_11965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_11995	COG1309	transcriptional regulator
KM400_12010	COG0577	efflux transmembrane transporter activity
KM400_12010	COG1136	(ABC) transporter
KM400_12015	COG0500	methyltransferase
KM400_12015	COG3615	Tellurite resistance protein tehB
KM400_12025	COG2226	methyltransferase
KM400_12030	COG3961	Belongs to the TPP enzyme family
KM400_12035	COG1846	Transcriptional regulator
KM400_12075	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM400_12090	COG1595	DNA-templated transcription, initiation
KM400_12100	COG0768	penicillin binding
KM400_12105	COG0768	penicillin binding
KM400_12110	COG2367	Beta-lactamase
KM400_12120	COG1609	Transcriptional regulator
KM400_12130	COG0673	inositol 2-dehydrogenase activity
KM400_12140	COG1012	belongs to the aldehyde dehydrogenase family
KM400_12155	COG0191	fructose-bisphosphate aldolase activity
KM400_12175	COG0737	Belongs to the 5'-nucleotidase family
KM400_12185	COG0457	Tetratricopeptide repeat
KM400_12190	COG1476	TRANSCRIPTIONal
KM400_12205	COG1876	peptidase activity
KM400_12225	COG1309	transcriptional regulator
KM400_12230	COG0488	(ABC) transporter
KM400_12245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_12280	COG1131	(ABC) transporter
KM400_12290	COG1309	transcriptional regulator
KM400_12305	COG1960	acyl-CoA dehydrogenase activity
KM400_12310	COG0439	Biotin carboxylase
KM400_12315	COG0511	ligase activity, forming carbon-carbon bonds
KM400_12320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM400_12325	COG1024	Enoyl-CoA hydratase
KM400_12330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM400_12335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM400_12345	COG1247	-acetyltransferase
KM400_12350	COG0572	uridine kinase
KM400_12360	COG2318	DinB family
KM400_12365	COG1686	Belongs to the peptidase S11 family
KM400_12390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM400_12430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM400_12430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM400_12455	COG2814	Major facilitator Superfamily
KM400_12475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM400_12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_12510	COG1063	alcohol dehydrogenase
KM400_12540	COG3773	Cell wall hydrolase
KM400_12550	COG0745	RESPONSE REGULATOR receiver
KM400_12565	COG0488	(ABC) transporter
KM400_12580	COG1136	(ABC) transporter
KM400_12605	COG0460	homoserine dehydrogenase
KM400_12610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_12620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM400_12685	COG2124	cytochrome p450
KM400_12720	COG0561	phosphatase activity
KM400_12730	COG5002	protein histidine kinase activity
KM400_12735	COG0768	penicillin binding
KM400_12740	COG1819	glycosyl
KM400_12745	COG1794	racemase activity, acting on amino acids and derivatives
KM400_12755	COG1122	ATPase activity
KM400_12770	COG2205	protein histidine kinase activity
KM400_12780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM400_12785	COG0604	alcohol dehydrogenase
KM400_12790	COG0768	penicillin binding
KM400_12800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM400_12835	COG0693	protein deglycase activity
KM400_12865	COG2814	Major facilitator Superfamily
KM400_12880	COG0584	glycerophosphoryl diester phosphodiesterase
KM400_12925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM400_12935	COG2223	nitrite transmembrane transporter activity
KM400_12950	COG2816	NAD+ diphosphatase activity
KM400_12955	COG0592	DNA-directed DNA polymerase activity
KM400_12960	COG1051	belongs to the nudix hydrolase family
KM400_12995	COG3878	Protein conserved in bacteria
KM400_13040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM400_13055	COG0322	excinuclease ABC activity
KM400_13095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM400_13120	COG1011	Hydrolase
KM400_13135	COG0657	acetylesterase activity
KM400_13140	COG0076	glutamate decarboxylase activity
KM400_13155	COG1523	belongs to the glycosyl hydrolase 13 family
KM400_13160	COG3227	Zinc metalloprotease (Elastase)
KM400_13180	COG0201	protein transport
KM400_13190	COG0697	spore germination
KM400_13195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_13225	COG4129	membrane
KM400_13230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_13245	COG2959	enzyme of heme biosynthesis
KM400_13265	COG3483	tryptophan 2,3-dioxygenase activity
KM400_13270	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM400_13275	COG3844	kynureninase activity
KM400_13280	COG1309	transcriptional regulator
KM400_13310	COG3284	Transcriptional regulator
KM400_13330	COG1349	DNA-binding transcription factor activity
KM400_13350	COG1959	2 iron, 2 sulfur cluster binding
KM400_13365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM400_13370	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM400_13375	COG0022	dehydrogenase e1 component
KM400_13380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM400_13390	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_13395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM400_13395	COG0456	acetyltransferase
KM400_13425	COG4176	ABC-type proline glycine betaine transport system permease component
KM400_13430	COG0517	IMP dehydrogenase activity
KM400_13430	COG4175	Glycine betaine
KM400_13455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM400_13460	COG2153	protein acetylation
KM400_13465	COG3397	chitin binding
KM400_13480	COG2205	protein histidine kinase activity
KM400_13505	COG0658	competence protein
KM400_13505	COG2333	competence protein COMEC
KM400_13555	COG3973	AAA domain
KM400_13570	COG2105	PFAM AIG2 family protein
KM400_13575	COG0514	ATP-dependent DNA helicase (RecQ)
KM400_13595	COG4637	Psort location Cytoplasmic, score
KM400_13620	COG3397	chitin binding
KM400_13635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM400_13640	COG1115	amino acid carrier protein
KM400_13645	COG1012	belongs to the aldehyde dehydrogenase family
KM400_13650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM400_13660	COG3938	Belongs to the proline racemase family
KM400_13665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM400_13705	COG0586	Pfam SNARE associated Golgi protein
KM400_13720	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM400_13725	COG0519	Catalyzes the synthesis of GMP from XMP
KM400_13730	COG4166	transmembrane transport
KM400_13740	COG4948	Mandelate Racemase Muconate Lactonizing
KM400_13785	COG2936	dipeptidyl-peptidase activity
KM400_13790	COG5002	protein histidine kinase activity
KM400_13795	COG0745	RESPONSE REGULATOR receiver
KM400_13830	COG1164	Oligoendopeptidase f
KM400_13845	COG1307	EDD domain protein, DegV family
KM400_13865	COG2814	Major facilitator Superfamily
KM400_13875	COG1664	Polymer-forming cytoskeletal
KM400_13880	COG0789	Transcriptional regulator
KM400_13885	COG4533	DNA binding
KM400_13890	COG0477	Major facilitator Superfamily
KM400_13890	COG2814	Major facilitator Superfamily
KM400_13910	COG2261	transglycosylase associated protein
KM400_13925	COG2226	methyltransferase
KM400_13960	COG0436	Aminotransferase
KM400_13965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM400_13970	COG5146	pantothenate kinase activity
KM400_13990	COG1131	(ABC) transporter
KM400_14035	COG0628	permease
KM400_14045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM400_14050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM400_14055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM400_14060	COG1116	anion transmembrane transporter activity
KM400_14080	COG2816	NAD+ diphosphatase activity
KM400_14100	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM400_14125	COG0697	spore germination
KM400_14130	COG2318	DinB family
KM400_14150	COG4912	Dna alkylation repair
KM400_14170	COG0861	Integral membrane protein TerC family
KM400_14175	COG1368	sulfuric ester hydrolase activity
KM400_14180	COG0488	(ABC) transporter
KM400_14195	COG1309	transcriptional regulator
KM400_14210	COG0287	Prephenate dehydrogenase
KM400_14215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM400_14220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM400_14225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM400_14225	COG1605	Chorismate mutase
KM400_14260	COG1388	LysM domain
KM400_14260	COG3584	3D domain protein
KM400_14270	COG1595	DNA-templated transcription, initiation
KM400_14295	COG1879	ABC-type sugar transport system periplasmic component
KM400_14305	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM400_14315	COG2390	Transcriptional regulator
KM400_14320	COG1070	Carbohydrate kinase
KM400_14350	COG2329	Antibiotic biosynthesis monooxygenase
KM400_14370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_14380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM400_14385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM400_14390	COG4187	Peptidase family M20/M25/M40
KM400_14395	COG1414	Transcriptional regulator
KM400_14400	COG0833	amino acid
KM400_14405	COG1690	Belongs to the RtcB family
KM400_14410	COG3239	Fatty acid desaturase
KM400_14415	COG1785	Belongs to the alkaline phosphatase family
KM400_14425	COG3655	Transcriptional regulator
KM400_14440	COG4377	Putative membrane peptidase family (DUF2324)
KM400_14450	COG3279	Response regulator of the LytR AlgR family
KM400_14460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_14465	COG0346	lactoylglutathione lyase activity
KM400_14485	COG0714	Associated with various cellular activities
KM400_14510	COG0463	Glycosyl transferase, family 2
KM400_14535	COG0463	Glycosyl transferase, family 2
KM400_14545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM400_14550	COG0753	catalase activity
KM400_14560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM400_14585	COG0714	Associated with various cellular activities
KM400_14595	COG0778	Nitroreductase
KM400_14600	COG1846	Transcriptional regulator
KM400_14635	COG1725	Transcriptional regulator
KM400_14645	COG0577	efflux transmembrane transporter activity
KM400_14645	COG1136	(ABC) transporter
KM400_14670	COG2207	Transcriptional regulator
KM400_14675	COG0456	acetyltransferase
KM400_14695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_14715	COG0642	Histidine kinase
KM400_14720	COG0745	RESPONSE REGULATOR receiver
KM400_14725	COG0596	Alpha beta hydrolase
KM400_14755	COG0730	response to heat
KM400_14765	COG0833	amino acid
KM400_14775	COG4335	DNA alkylation repair
KM400_14815	COG0768	penicillin binding
KM400_14825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM400_14860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM400_14865	COG1414	Transcriptional regulator
KM400_14880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM400_14885	COG0640	Transcriptional regulator
KM400_14895	COG1960	acyl-CoA dehydrogenase activity
KM400_14910	COG3314	Sporulation integral membrane protein YlbJ
KM400_14925	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM400_14940	COG0574	Belongs to the PEP-utilizing enzyme family
KM400_14940	COG3848	Pyruvate phosphate dikinase
KM400_14945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_14960	COG5577	PFAM Coat F domain
KM400_14965	COG3403	YqcI/YcgG family
KM400_14970	COG1280	lysine exporter protein (LysE YggA)
KM400_15005	COG1063	alcohol dehydrogenase
KM400_15020	COG1027	Aspartate ammonia-lyase
KM400_15025	COG0252	asparaginase activity
KM400_15030	COG1396	sequence-specific DNA binding
KM400_15040	COG0322	excinuclease ABC activity
KM400_15045	COG0531	amino acid
KM400_15050	COG1114	Component of the transport system for branched-chain amino acids
KM400_15055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM400_15065	COG0281	malic enzyme
KM400_15080	COG0531	amino acid
KM400_15090	COG0784	Response regulator, receiver
KM400_15100	COG2066	Belongs to the glutaminase family
KM400_15105	COG1115	amino acid carrier protein
KM400_15135	COG0737	Belongs to the 5'-nucleotidase family
KM400_15140	COG0753	catalase activity
KM400_15145	COG2267	carboxylic ester hydrolase activity
KM400_15150	COG1335	isochorismatase
KM400_15170	COG0583	DNA-binding transcription factor activity
KM400_15175	COG1846	Transcriptional regulator
KM400_15180	COG0598	Magnesium transport protein CorA
KM400_15215	COG0415	Belongs to the DNA photolyase family
KM400_15220	COG0288	reversible hydration of carbon dioxide
KM400_15230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM400_15235	COG5609	conserved protein (DUF2294)
KM400_15250	COG1575	Belongs to the MenA family. Type 1 subfamily
KM400_15255	COG2267	carboxylic ester hydrolase activity
KM400_15260	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM400_15265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM400_15270	COG1121	(ABC) transporter
KM400_15300	COG0798	PFAM Bile acid sodium symporter
KM400_15305	COG0346	lactoylglutathione lyase activity
KM400_15310	COG0640	Transcriptional regulator
KM400_15325	COG0443	Heat shock 70 kDa protein
KM400_15340	COG1522	sequence-specific DNA binding
KM400_15360	COG0346	lactoylglutathione lyase activity
KM400_15380	COG2169	Transcriptional regulator
KM400_15425	COG2814	Major facilitator Superfamily
KM400_15450	COG0745	RESPONSE REGULATOR receiver
KM400_15455	COG3850	Histidine kinase
KM400_15455	COG5002	protein histidine kinase activity
KM400_15480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM400_15500	COG1476	TRANSCRIPTIONal
KM400_15515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_15520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM400_15530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_15535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM400_15550	COG1136	(ABC) transporter
KM400_15555	COG0577	efflux transmembrane transporter activity
KM400_15570	COG3850	Histidine kinase
KM400_15570	COG5002	protein histidine kinase activity
KM400_15580	COG2364	Membrane
KM400_15585	COG1846	Transcriptional regulator
KM400_15595	COG2808	Putative FMN-binding domain
KM400_15600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_15605	COG2271	Major facilitator Superfamily
KM400_15610	COG1556	Lactate utilization protein
KM400_15615	COG1139	Iron-sulfur cluster binding protein
KM400_15625	COG0583	DNA-binding transcription factor activity
KM400_15635	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM400_15665	COG0673	inositol 2-dehydrogenase activity
KM400_15670	COG0561	phosphatase activity
KM400_15680	COG1609	Transcriptional regulator
KM400_15685	COG0457	Tetratricopeptide repeat
KM400_15705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM400_15735	COG0534	Mate efflux family protein
KM400_15755	COG2814	Major facilitator Superfamily
KM400_15760	COG1309	transcriptional regulator
KM400_15775	COG0814	amino acid
KM400_15780	COG1760	l-serine dehydratase
KM400_15795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM400_15800	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM400_15815	COG1522	sequence-specific DNA binding
KM400_15820	COG0531	amino acid
KM400_15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM400_15855	COG1595	DNA-templated transcription, initiation
KM400_15870	COG0662	Cupin 2, conserved barrel domain protein
KM400_15875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_15875	COG2207	Transcriptional regulator
KM400_15925	COG0477	Major facilitator Superfamily
KM400_15935	COG1846	Transcriptional regulator
KM400_15940	COG2814	Major facilitator Superfamily
KM400_15950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM400_15955	COG1131	(ABC) transporter
KM400_15975	COG2076	Multidrug Resistance protein
KM400_15980	COG1309	transcriptional regulator
KM400_15990	COG2031	fatty acid transporter
KM400_16000	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM400_16030	COG1122	ATPase activity
KM400_16035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM400_16050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM400_16055	COG1288	antiporter activity
KM400_16060	COG2356	endonuclease I
KM400_16075	COG3620	sequence-specific DNA binding
KM400_16080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM400_16085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM400_16090	COG0124	histidyl-tRNA synthetase
KM400_16105	COG1733	regulation of RNA biosynthetic process
KM400_16110	COG0778	Nitroreductase
KM400_16130	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_16140	COG1131	(ABC) transporter
KM400_16165	COG1011	Hydrolase
KM400_16175	COG2365	Tyrosine phosphatase family
KM400_16200	COG0346	lactoylglutathione lyase activity
KM400_16205	COG1940	carbohydrate kinase activity
KM400_16210	COG0738	Major facilitator superfamily
KM400_16215	COG0110	maltose O-acetyltransferase activity
KM400_16225	COG0577	efflux transmembrane transporter activity
KM400_16225	COG1136	(ABC) transporter
KM400_16240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM400_16245	COG0628	permease
KM400_16265	COG2226	methyltransferase
KM400_16275	COG0477	Major facilitator Superfamily
KM400_16305	COG1253	flavin adenine dinucleotide binding
KM400_16310	COG0789	Transcriptional regulator
KM400_16315	COG0697	spore germination
KM400_16320	COG1357	PFAM Pentapeptide repeats (8 copies)
KM400_16325	COG3813	Protein conserved in bacteria
KM400_16330	COG2706	6-phosphogluconolactonase activity
KM400_16335	COG1070	Carbohydrate kinase
KM400_16345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM400_16350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM400_16360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM400_16365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM400_16370	COG0604	alcohol dehydrogenase
KM400_16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM400_16385	COG0604	alcohol dehydrogenase
KM400_16385	COG3321	synthase
KM400_16390	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_16415	COG0656	L-ascorbic acid biosynthetic process
KM400_16420	COG2814	Major facilitator Superfamily
KM400_16435	COG0346	lactoylglutathione lyase activity
KM400_16440	COG0814	amino acid
KM400_16465	COG1393	Belongs to the ArsC family
KM400_16470	COG1733	regulation of RNA biosynthetic process
KM400_16475	COG2188	Transcriptional regulator
KM400_16480	COG0673	inositol 2-dehydrogenase activity
KM400_16485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM400_16490	COG1733	regulation of RNA biosynthetic process
KM400_16495	COG1733	regulation of RNA biosynthetic process
KM400_16510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_16530	COG0384	phenazine biosynthesis protein PhzF
KM400_16540	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_16550	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_16560	COG1733	regulation of RNA biosynthetic process
KM400_16595	COG1191	sigma factor activity
KM400_16610	COG1309	transcriptional regulator
KM400_16630	COG3152	Membrane
KM400_16655	COG1151	hydroxylamine reductase activity
KM400_16665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_16670	COG3409	Peptidoglycan-binding domain 1 protein
KM400_16670	COG3757	hydrolase, family 25
KM400_16705	COG2072	flavoprotein involved in K transport
KM400_16740	COG0604	alcohol dehydrogenase
KM400_16745	COG1113	amino acid transport
KM400_16750	COG2814	Major facilitator Superfamily
KM400_16780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM400_16785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM400_16805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_16810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_16815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_16820	COG3739	integral membrane protein
KM400_16825	COG0384	phenazine biosynthesis protein PhzF
KM400_16855	COG0583	DNA-binding transcription factor activity
KM400_16875	COG1193	negative regulation of DNA recombination
KM400_16890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM400_16895	COG1164	Oligoendopeptidase f
KM400_16900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM400_16930	COG0584	glycerophosphoryl diester phosphodiesterase
KM400_16955	COG0640	Transcriptional regulator
KM400_16960	COG0604	alcohol dehydrogenase
KM400_16980	COG2808	Putative FMN-binding domain
KM400_16995	COG0385	Bile acid
KM400_17000	COG0277	FAD linked oxidase domain protein
KM400_17030	COG1216	Glycosyl transferase, family 2
KM400_17035	COG1024	Enoyl-CoA hydratase
KM400_17045	COG1285	pathogenesis
KM400_17060	COG2514	catechol 2,3-dioxygenase activity
KM400_17065	COG2720	vancomycin resistance protein
KM400_17105	COG0716	FMN binding
KM400_17135	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_17160	COG4145	pantothenate transmembrane transporter activity
KM400_17170	COG1012	belongs to the aldehyde dehydrogenase family
KM400_17175	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_17185	COG1657	PFAM Prenyltransferase squalene oxidase
KM400_17190	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM400_17195	COG2962	Rard protein
KM400_17200	COG3326	Membrane
KM400_17215	COG0489	protein tyrosine kinase activity
KM400_17225	COG0314	molybdopterin synthase activity
KM400_17230	COG0303	'Molybdopterin
KM400_17235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM400_17240	COG2116	formate transmembrane transporter activity
KM400_17250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM400_17255	COG5609	conserved protein (DUF2294)
KM400_17260	COG2427	Protein of unknown function (DUF1641)
KM400_17265	COG3383	formate dehydrogenase (NAD+) activity
KM400_17275	COG0697	spore germination
KM400_17315	COG2226	methyltransferase
KM400_17320	COG4166	transmembrane transport
KM400_17325	COG4166	transmembrane transport
KM400_17330	COG1301	dicarboxylic acid transport
KM400_17335	COG1316	TRANSCRIPTIONal
KM400_17345	COG1595	DNA-templated transcription, initiation
KM400_17365	COG1131	(ABC) transporter
KM400_17375	COG0673	inositol 2-dehydrogenase activity
KM400_17380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM400_17385	COG0187	DNA topoisomerase II activity
KM400_17390	COG1832	CoA-binding protein
KM400_17395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM400_17400	COG0745	RESPONSE REGULATOR receiver
KM400_17415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM400_17420	COG4841	protein insertion into membrane
KM400_17425	COG0824	Thioesterase
KM400_17455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM400_17465	COG2274	protein secretion by the type I secretion system
KM400_17470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM400_17510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM400_17525	COG0183	Belongs to the thiolase family
KM400_17530	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_17535	COG1268	BioY protein
KM400_17540	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_17590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_17600	COG5002	protein histidine kinase activity
KM400_17605	COG0400	carboxylic ester hydrolase activity
KM400_17610	COG0346	lactoylglutathione lyase activity
KM400_17615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM400_17620	COG0069	glutamate synthase activity
KM400_17625	COG1902	pentaerythritol trinitrate reductase activity
KM400_17630	COG1329	Transcriptional regulator
KM400_17635	COG0010	Belongs to the arginase family
KM400_17660	COG2226	methyltransferase
KM400_17715	COG4846	Membrane protein involved in cytochrome C biogenesis
KM400_17720	COG0785	Cytochrome C biogenesis protein
KM400_17730	COG0583	DNA-binding transcription factor activity
KM400_17735	COG1380	Effector of murein hydrolase LrgA
KM400_17740	COG1346	cytolysis
KM400_17765	COG3409	Peptidoglycan-binding domain 1 protein
KM400_17765	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM400_17780	COG1132	(ABC) transporter
KM400_17785	COG1132	(ABC) transporter
KM400_17815	COG3639	organic phosphonate transmembrane transporter activity
KM400_17820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM400_17840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM400_17860	COG1695	Transcriptional regulator
KM400_17895	COG1388	LysM domain
KM400_17895	COG3409	Peptidoglycan-binding domain 1 protein
KM400_17895	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM400_17900	COG4824	toxin secretion phage lysis holin
KM400_18045	COG1595	DNA-templated transcription, initiation
KM400_18090	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM400_18175	COG1396	sequence-specific DNA binding
KM400_18200	COG0174	glutamine synthetase
KM400_18205	COG0789	Transcriptional regulator
KM400_18210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM400_18215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM400_18220	COG2860	membrane
KM400_18225	COG0464	growth
KM400_18255	COG3584	3D domain protein
KM400_18255	COG1388	LysM domain
KM400_18260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM400_18260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM400_18260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM400_18265	COG1105	Belongs to the carbohydrate kinase PfkB family
KM400_18270	COG1349	DNA-binding transcription factor activity
KM400_18280	COG2322	membrane
KM400_18290	COG1113	amino acid transport
KM400_18305	COG1408	metallophosphoesterase
KM400_18310	COG2116	formate transmembrane transporter activity
KM400_18320	COG2217	Heavy metal translocating P-type atpase
KM400_18325	COG2608	mercury ion transmembrane transporter activity
KM400_18330	COG1937	Protein conserved in bacteria
KM400_18340	COG2819	hydrolase of the alpha beta superfamily
KM400_18345	COG1120	ATPase activity
KM400_18350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_18370	COG2169	Transcriptional regulator
KM400_18375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM400_18380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM400_18390	COG2364	Membrane
KM400_18410	COG0346	lactoylglutathione lyase activity
KM400_18415	COG3300	MHYT domain
KM400_18415	COG5001	Diguanylate cyclase
KM400_18435	COG1346	cytolysis
KM400_18440	COG1380	Effector of murein hydrolase LrgA
KM400_18445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM400_18450	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM400_18450	COG0596	Alpha beta hydrolase
KM400_18455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM400_18475	COG1404	Belongs to the peptidase S8 family
KM400_18480	COG3773	Cell wall hydrolase
KM400_18485	COG0562	UDP-galactopyranose mutase
KM400_18490	COG1368	sulfuric ester hydrolase activity
KM400_18495	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM400_18505	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM400_18530	COG1131	(ABC) transporter
KM400_18550	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM400_18555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM400_18560	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM400_18565	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM400_18565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM400_18575	COG2359	stage V sporulation protein S
KM400_18580	COG1692	metallophosphoesterase
KM400_18605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM400_18610	COG1426	Protein conserved in bacteria
KM400_18625	COG0300	oxidoreductase activity
KM400_18630	COG0612	Peptidase, M16
KM400_18635	COG0612	Peptidase, M16
KM400_18640	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM400_18650	COG3845	ABC transporter
KM400_18655	COG1744	ABC transporter substrate-binding protein PnrA-like
KM400_18660	COG2188	Transcriptional regulator
KM400_18665	COG1674	ftsk spoiiie
KM400_18675	COG0740	serine-type endopeptidase activity
KM400_18680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM400_18690	COG0527	aspartate kinase activity
KM400_18695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM400_18700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM400_18705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM400_18710	COG1873	PFAM PRC-barrel domain
KM400_18715	COG0612	Peptidase, M16
KM400_18720	COG0726	polysaccharide deacetylase
KM400_18735	COG0196	riboflavin kinase activity
KM400_18740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM400_18750	COG1550	Protein conserved in bacteria
KM400_18760	COG1358	cellular component organization or biogenesis
KM400_18765	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM400_18770	COG0195	Participates in both transcription termination and antitermination
KM400_18790	COG0750	zinc metalloprotease
KM400_18800	COG4589	Belongs to the CDS family
KM400_18815	COG0528	UMP kinase activity
KM400_18845	COG4974	Belongs to the 'phage' integrase family
KM400_18855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM400_18865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM400_18905	COG1837	Belongs to the UPF0109 family
KM400_18915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM400_18925	COG0552	protein localization to endoplasmic reticulum
KM400_18930	COG1196	nuclear chromosome segregation
KM400_18940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM400_18945	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_18950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM400_18965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM400_18970	COG1461	Dihydroxyacetone kinase
KM400_18975	COG1302	Protein conserved in bacteria
KM400_18990	COG1564	THIamine pyrophosphokinase
KM400_18995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM400_19000	COG1162	GTPase activity
KM400_19005	COG2815	serine threonine protein kinase
KM400_19005	COG0515	serine threonine protein kinase
KM400_19010	COG0631	protein serine/threonine phosphatase activity
KM400_19020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM400_19020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM400_19030	COG0242	peptide deformylase activity
KM400_19035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM400_19040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM400_19060	COG1561	YicC-like family, N-terminal region
KM400_19065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM400_19075	COG0006	proline dipeptidase activity
KM400_19090	COG3069	C4-dicarboxylate transmembrane transporter activity
KM400_19155	COG0564	pseudouridine synthase activity
KM400_19175	COG3599	regulation of cell shape
KM400_19180	COG2302	S4 RNA-binding domain
KM400_19185	COG0762	integral membrane protein
KM400_19195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM400_19200	COG1496	oxidoreductase activity
KM400_19205	COG1873	PFAM PRC-barrel domain
KM400_19210	COG1191	sigma factor activity
KM400_19215	COG1191	sigma factor activity
KM400_19225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM400_19230	COG0849	cell division
KM400_19235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM400_19240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM400_19250	COG0772	Belongs to the SEDS family
KM400_19265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM400_19270	COG0768	penicillin binding
KM400_19275	COG0768	penicillin binding
KM400_19280	COG4839	cell division protein FtsL
KM400_19295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM400_19310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM400_19315	COG1399	metal-binding, possibly nucleic acid-binding protein
KM400_19365	COG4824	toxin secretion phage lysis holin
KM400_19450	COG4626	Terminase
KM400_19450	COG1802	Transcriptional regulator
KM400_19475	COG0582	viral genome integration into host DNA
KM400_19540	COG0756	dUTP diphosphatase activity
KM400_19555	COG1191	sigma factor activity
KM400_19580	COG1484	DNA-dependent DNA replication
KM400_19605	COG1396	sequence-specific DNA binding
KM400_19620	COG1396	sequence-specific DNA binding
KM400_19635	COG0582	viral genome integration into host DNA
KM400_19645	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM400_19650	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM400_19655	COG3314	Sporulation integral membrane protein YlbJ
KM400_19665	COG0742	ribosomal rna small subunit methyltransferase
KM400_19680	COG3679	Belongs to the UPF0342 family
KM400_19685	COG0406	alpha-ribazole phosphatase activity
KM400_19700	COG2340	Cysteine-rich secretory protein family
KM400_19715	COG3336	cytochrome c oxidase
KM400_19750	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM400_19755	COG0772	Belongs to the SEDS family
KM400_19765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM400_19770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM400_19780	COG4896	Protein conserved in bacteria
KM400_19795	COG1217	gtp-binding protein TYPA
KM400_19805	COG0483	inositol monophosphate 1-phosphatase activity
KM400_19825	COG1982	Orn Lys Arg decarboxylase major
KM400_19875	COG0022	dehydrogenase e1 component
KM400_19880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM400_19890	COG0242	peptide deformylase activity
KM400_19905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM400_19910	COG0569	domain protein
KM400_19930	COG0583	DNA-binding transcription factor activity
KM400_19935	COG0517	IMP dehydrogenase activity
KM400_19945	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM400_19955	COG4703	Protein of unknown function (DUF1797)
KM400_19970	COG2200	EAL domain
KM400_19975	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_19980	COG1408	metallophosphoesterase
KM400_20025	COG2814	Major facilitator Superfamily
KM400_20045	COG3209	COG3209 Rhs family protein
KM400_20055	COG2205	protein histidine kinase activity
KM400_20065	COG0436	Aminotransferase
KM400_20070	COG1609	Transcriptional regulator
KM400_20075	COG3833	ABC-type maltose transport systems, permease component
KM400_20080	COG1175	transmembrane transport
KM400_20085	COG2182	Extracellular solute-binding protein
KM400_20095	COG0366	Alpha amylase catalytic
KM400_20100	COG3842	ATPase activity
KM400_20140	COG0183	Belongs to the thiolase family
KM400_20175	COG1695	Transcriptional regulator
KM400_20180	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_20190	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM400_20200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM400_20205	COG0436	Aminotransferase
KM400_20225	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM400_20245	COG2199	diguanylate cyclase activity
KM400_20250	COG0778	Nitroreductase
KM400_20275	COG1263	PTS System
KM400_20275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM400_20275	COG2190	(PTS) system
KM400_20280	COG3711	transcriptional antiterminator
KM400_20290	COG2188	Transcriptional regulator
KM400_20300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM400_20325	COG1547	Domain of unknown function (DUF309)
KM400_20330	COG0456	acetyltransferase
KM400_20335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM400_20340	COG4086	secreted protein
KM400_20345	COG0561	phosphatase activity
KM400_20350	COG0697	spore germination
KM400_20365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_20390	COG0733	neurotransmitter:sodium symporter activity
KM400_20410	COG1686	Belongs to the peptidase S11 family
KM400_20415	COG1725	Transcriptional regulator
KM400_20420	COG1131	(ABC) transporter
KM400_20435	COG1846	Transcriptional regulator
KM400_20450	COG0598	Magnesium transport protein CorA
KM400_20475	COG4974	Belongs to the 'phage' integrase family
KM400_20485	COG0735	belongs to the Fur family
KM400_20490	COG1300	Membrane
KM400_20510	COG0667	Aldo Keto reductase
KM400_20515	COG0656	L-ascorbic acid biosynthetic process
KM400_20520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM400_20520	COG0456	acetyltransferase
KM400_20530	COG1525	nuclease
KM400_20530	COG4085	toxin activity
KM400_20530	COG0737	Belongs to the 5'-nucleotidase family
KM400_20540	COG0596	Alpha beta hydrolase
KM400_20545	COG2056	Na+-H+ antiporter family
KM400_20550	COG1609	Transcriptional regulator
KM400_20555	COG0456	acetyltransferase
KM400_20560	COG1073	alpha beta
KM400_20575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM400_20575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM400_20580	COG0307	riboflavin synthase, alpha
KM400_20605	COG4106	trans-aconitate 2-methyltransferase activity
KM400_20610	COG1073	alpha beta
KM400_20610	COG2226	methyltransferase
KM400_20625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM400_20635	COG1757	Na H antiporter
KM400_20640	COG0737	Belongs to the 5'-nucleotidase family
KM400_20650	COG1522	sequence-specific DNA binding
KM400_20670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM400_20680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM400_20695	COG0300	oxidoreductase activity
KM400_20700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_20705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM400_20710	COG1760	l-serine dehydratase
KM400_20715	COG1760	l-serine dehydratase
KM400_20735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM400_20745	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM400_20750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_20765	COG1376	ErfK ybiS ycfS ynhG family protein
KM400_20770	COG4129	membrane
KM400_20775	COG1126	abc transporter atp-binding protein
KM400_20780	COG0765	amino acid transport
KM400_20785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM400_20800	COG2816	NAD+ diphosphatase activity
KM400_20805	COG0772	Belongs to the SEDS family
KM400_20810	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM400_20815	COG0022	dehydrogenase e1 component
KM400_20820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM400_20825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM400_20840	COG0280	phosphate acetyltransferase
KM400_20845	COG3290	protein histidine kinase activity
KM400_20845	COG3829	transcription factor binding
KM400_20855	COG0584	glycerophosphoryl diester phosphodiesterase
KM400_20860	COG3093	addiction module antidote protein HigA
KM400_20870	COG0745	RESPONSE REGULATOR receiver
KM400_20875	COG0750	zinc metalloprotease
KM400_20880	COG0497	DNA recombination
KM400_20890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM400_20900	COG0142	geranyltranstransferase activity
KM400_20925	COG1302	Protein conserved in bacteria
KM400_20930	COG0439	Biotin carboxylase
KM400_20935	COG0511	ligase activity, forming carbon-carbon bonds
KM400_20980	COG3854	ATPases associated with a variety of cellular activities
KM400_21005	COG0006	proline dipeptidase activity
KM400_21020	COG3872	metal-dependent enzyme
KM400_21030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM400_21050	COG0095	Lipoate-protein ligase
KM400_21055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM400_21060	COG1609	Transcriptional regulator
KM400_21070	COG2076	Multidrug Resistance protein
KM400_21075	COG2076	Multidrug Resistance protein
KM400_21110	COG1131	(ABC) transporter
KM400_21115	COG1725	Transcriptional regulator
KM400_21145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM400_21200	COG4970	Tfp pilus assembly protein FimT
KM400_21210	COG1459	type II secretion system
KM400_21215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM400_21265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM400_21275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM400_21275	COG0646	methionine synthase
KM400_21280	COG0626	cystathionine gamma-synthase activity
KM400_21285	COG0626	cystathionine gamma-synthase activity
KM400_21305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_21315	COG1940	carbohydrate kinase activity
KM400_21320	COG4483	Protein conserved in bacteria
KM400_21325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM400_21330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM400_21335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM400_21340	COG0704	Plays a role in the regulation of phosphate uptake
KM400_21350	COG0581	inorganic phosphate transmembrane transporter activity
KM400_21355	COG0573	inorganic phosphate transmembrane transporter activity
KM400_21360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM400_21365	COG0768	penicillin binding
KM400_21370	COG0477	Major facilitator Superfamily
KM400_21375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM400_21400	COG0735	belongs to the Fur family
KM400_21405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM400_21410	COG1121	(ABC) transporter
KM400_21415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_21445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM400_21450	COG2384	SAM-dependent methyltransferase
KM400_21455	COG2010	Cytochrome c
KM400_21460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM400_21465	COG0358	DNA primase activity
KM400_21480	COG0517	IMP dehydrogenase activity
KM400_21495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM400_21500	COG0295	cytidine deaminase activity
KM400_21505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM400_21515	COG1480	7TM receptor with intracellular HD hydrolase
KM400_21520	COG1702	phosphate starvation-inducible protein PhoH
KM400_21535	COG1610	YqeY-like protein
KM400_21540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM400_21545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM400_21550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM400_21580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM400_21585	COG1733	regulation of RNA biosynthetic process
KM400_21610	COG1466	dna polymerase III delta subunit
KM400_21620	COG0658	competence protein
KM400_21620	COG2333	competence protein COMEC
KM400_21625	COG2131	deaminase
KM400_21630	COG1555	photosystem II stabilization
KM400_21630	COG1596	polysaccharide export
KM400_21635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM400_21640	COG2226	methyltransferase
KM400_21645	COG0799	negative regulation of ribosome biogenesis
KM400_21650	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM400_21660	COG1534	Rna-binding protein
KM400_21670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM400_21675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM400_21700	COG1595	DNA-templated transcription, initiation
KM400_21710	COG0778	Nitroreductase
KM400_21715	COG2357	RelA SpoT domain protein
KM400_21725	COG1785	Belongs to the alkaline phosphatase family
KM400_21735	COG2267	carboxylic ester hydrolase activity
KM400_21770	COG1404	Belongs to the peptidase S8 family
KM400_21775	COG3186	Phenylalanine-4-hydroxylase
KM400_21785	COG2514	catechol 2,3-dioxygenase activity
KM400_21790	COG2259	Doxx family
KM400_21830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_21840	COG1012	belongs to the aldehyde dehydrogenase family
KM400_21840	COG1454	alcohol dehydrogenase
KM400_21845	COG0626	cystathionine gamma-synthase activity
KM400_21850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM400_21875	COG0768	penicillin binding
KM400_21890	COG0826	peptidase U32
KM400_21895	COG0826	peptidase U32
KM400_21900	COG4122	O-methyltransferase activity
KM400_21905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM400_21925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM400_21935	COG0628	permease
KM400_21955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM400_21965	COG0482	sulfurtransferase activity
KM400_21970	COG1104	cysteine desulfurase activity
KM400_21975	COG1959	2 iron, 2 sulfur cluster binding
KM400_21980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM400_21990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM400_22015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM400_22025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM400_22025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM400_22030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM400_22035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM400_22035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM400_22045	COG2244	polysaccharide biosynthetic process
KM400_22050	COG2323	membrane
KM400_22060	COG1862	Preprotein translocase
KM400_22090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM400_22100	COG0697	spore germination
KM400_22105	COG0697	spore germination
KM400_22110	COG0640	Transcriptional regulator
KM400_22135	COG0157	Belongs to the NadC ModD family
KM400_22140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM400_22145	COG1104	cysteine desulfurase activity
KM400_22150	COG1827	regulation of RNA biosynthetic process
KM400_22155	COG2258	MOSC domain
KM400_22160	COG0077	Prephenate dehydratase
KM400_22165	COG0577	efflux transmembrane transporter activity
KM400_22170	COG0577	efflux transmembrane transporter activity
KM400_22175	COG1136	(ABC) transporter
KM400_22185	COG0745	RESPONSE REGULATOR receiver
KM400_22190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM400_22195	COG3290	protein histidine kinase activity
KM400_22205	COG2868	ribosomal protein
KM400_22215	COG1530	ribonuclease E activity
KM400_22220	COG1994	Peptidase M50
KM400_22225	COG0739	heme binding
KM400_22230	COG2894	cell division
KM400_22250	COG1077	Cell shape determining protein MreB Mrl
KM400_22270	COG0285	dihydrofolate synthase activity
KM400_22275	COG0525	valine-tRNA ligase activity
KM400_22285	COG1388	LysM domain
KM400_22295	COG0113	porphobilinogen synthase activity
KM400_22300	COG1587	Uroporphyrinogen-III synthase
KM400_22310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM400_22320	COG1846	Transcriptional regulator
KM400_22325	COG1764	response to oxidative stress
KM400_22340	COG0470	DNA polymerase III
KM400_22340	COG1067	ATP-dependent peptidase activity
KM400_22385	COG0622	Phosphoesterase
KM400_22400	COG5401	PFAM Sporulation and spore germination
KM400_22420	COG1309	transcriptional regulator
KM400_22435	COG2197	response regulator
KM400_22440	COG2233	PERMEase
KM400_22450	COG0402	S-adenosylhomocysteine deaminase activity
KM400_22455	COG0402	S-adenosylhomocysteine deaminase activity
KM400_22465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM400_22475	COG0444	Belongs to the ABC transporter superfamily
KM400_22480	COG4608	Belongs to the ABC transporter superfamily
KM400_22485	COG3275	phosphorelay sensor kinase activity
KM400_22490	COG3279	Response regulator of the LytR AlgR family
KM400_22505	COG1983	PspC domain protein
KM400_22510	COG1396	sequence-specific DNA binding
KM400_22515	COG0697	spore germination
KM400_22525	COG1959	2 iron, 2 sulfur cluster binding
KM400_22530	COG1668	transmembrane transport
KM400_22535	COG4152	abc transporter atp-binding protein
KM400_22540	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM400_22550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM400_22555	COG1876	peptidase activity
KM400_22560	COG0824	Thioesterase
KM400_22565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM400_22570	COG1053	succinate dehydrogenase
KM400_22575	COG2009	succinate dehydrogenase
KM400_22580	COG1719	4-vinyl reductase, 4VR
KM400_22590	COG3118	belongs to the thioredoxin family
KM400_22595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM400_22600	COG2086	electron transfer activity
KM400_22605	COG1024	Enoyl-CoA hydratase
KM400_22610	COG1309	transcriptional regulator
KM400_22615	COG0318	PFAM AMP-dependent synthetase and ligase
KM400_22635	COG2318	DinB family
KM400_22665	COG1131	(ABC) transporter
KM400_22670	COG2205	protein histidine kinase activity
KM400_22675	COG0745	RESPONSE REGULATOR receiver
KM400_22685	COG4895	conserved protein (DUF2196)
KM400_22690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM400_22705	COG4509	Sortase family
KM400_22710	COG1120	ATPase activity
KM400_22725	COG5386	Cell surface protein
KM400_22735	COG5386	Cell surface protein
KM400_22740	COG1114	Component of the transport system for branched-chain amino acids
KM400_22745	COG1187	pseudouridine synthase activity
KM400_22755	COG1796	DNA polymerase
KM400_22755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM400_22760	COG1286	toxin biosynthetic process
KM400_22805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM400_22815	COG1418	mRNA catabolic process
KM400_22840	COG2814	Major facilitator Superfamily
KM400_22845	COG1566	PFAM secretion protein HlyD family protein
KM400_22850	COG1309	transcriptional regulator
KM400_22855	COG1363	Peptidase, m42
KM400_22880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM400_22890	COG1484	DNA-dependent DNA replication
KM400_22895	COG3611	Membrane attachment protein
KM400_22905	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM400_22910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM400_22915	COG0237	dephospho-CoA kinase activity
KM400_22920	COG1971	Probably functions as a manganese efflux pump
KM400_22930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM400_22930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM400_22935	COG5002	protein histidine kinase activity
KM400_22940	COG0745	RESPONSE REGULATOR receiver
KM400_22960	COG0538	isocitrate dehydrogenase activity
KM400_22965	COG0372	Belongs to the citrate synthase family
KM400_22975	COG0628	permease
KM400_22980	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM400_23005	COG1725	Transcriptional regulator
KM400_23010	COG0281	malic enzyme
KM400_23015	COG0587	DNA-directed DNA polymerase activity
KM400_23030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM400_23050	COG4109	DRTGG domain
KM400_23065	COG0006	proline dipeptidase activity
KM400_23100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_23105	COG0662	Cupin 2, conserved barrel domain protein
KM400_23115	COG1476	TRANSCRIPTIONal
KM400_23130	COG1028	Short-chain dehydrogenase reductase Sdr
KM400_23135	COG0589	response to stress
KM400_23175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_23195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM400_23200	COG0827	DNA restriction-modification system
KM400_23205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM400_23210	COG3874	Sporulation protein YtfJ
KM400_23225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM400_23235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM400_23250	COG1104	cysteine desulfurase activity
KM400_23260	COG0583	DNA-binding transcription factor activity
KM400_23265	COG0697	spore germination
KM400_23275	COG1956	GAF domain-containing protein
KM400_23280	COG0626	cystathionine gamma-synthase activity
KM400_23310	COG1595	DNA-templated transcription, initiation
KM400_23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM400_23325	COG0454	-acetyltransferase
KM400_23330	COG0517	IMP dehydrogenase activity
KM400_23335	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM400_23345	COG0745	RESPONSE REGULATOR receiver
KM400_23355	COG0666	response to abiotic stimulus
KM400_23390	COG1609	Transcriptional regulator
KM400_23395	COG4851	CamS sex pheromone cAM373 precursor
KM400_23400	COG3118	belongs to the thioredoxin family
KM400_23410	COG2309	aminopeptidase activity
KM400_23430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_23445	COG1674	ftsk spoiiie
KM400_23455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM400_23460	COG4848	Belongs to the UPF0354 family
KM400_23465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM400_23470	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM400_23475	COG1363	Peptidase, m42
KM400_23485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_23500	COG0510	thiamine kinase activity
KM400_23505	COG1523	belongs to the glycosyl hydrolase 13 family
KM400_23515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM400_23520	COG1349	DNA-binding transcription factor activity
KM400_23525	COG1187	pseudouridine synthase activity
KM400_23530	COG2244	polysaccharide biosynthetic process
KM400_23535	COG2081	HI0933 family
KM400_23540	COG2814	Major facilitator Superfamily
KM400_23550	COG3832	glyoxalase III activity
KM400_23570	COG1329	Transcriptional regulator
KM400_23580	COG4975	Glucose uptake
KM400_23595	COG0314	molybdopterin synthase activity
KM400_23600	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM400_23605	COG0303	'Molybdopterin
KM400_23615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM400_23620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM400_23640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM400_23650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM400_23695	COG2814	Major facilitator Superfamily
KM400_23700	COG0475	glutathione-regulated potassium exporter activity
KM400_23705	COG0490	domain, Protein
KM400_23710	COG0582	viral genome integration into host DNA
KM400_23720	COG1136	(ABC) transporter
KM400_23740	COG1242	4 iron, 4 sulfur cluster binding
KM400_23745	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM400_23750	COG1131	(ABC) transporter
KM400_23760	COG1794	racemase activity, acting on amino acids and derivatives
KM400_23780	COG2267	carboxylic ester hydrolase activity
KM400_23785	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM400_23790	COG0671	phosphoesterase, PA-phosphatase related
KM400_23795	COG0438	transferase activity, transferring glycosyl groups
KM400_23805	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM400_23860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM400_23865	COG5002	protein histidine kinase activity
KM400_23870	COG4191	Histidine kinase
KM400_23875	COG2267	carboxylic ester hydrolase activity
KM400_23895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM400_23900	COG1116	anion transmembrane transporter activity
KM400_23905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM400_23930	COG0494	nUDIX hydrolase
KM400_23960	COG0288	reversible hydration of carbon dioxide
KM400_23965	COG1271	oxidase subunit
KM400_23970	COG1294	oxidase, subunit
KM400_23990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_24015	COG1842	Phage shock protein A
KM400_24045	COG5002	protein histidine kinase activity
KM400_24050	COG0745	RESPONSE REGULATOR receiver
KM400_24075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM400_24080	COG1597	lipid kinase activity
KM400_24115	COG0586	Pfam SNARE associated Golgi protein
KM400_24125	COG0577	efflux transmembrane transporter activity
KM400_24130	COG1136	(ABC) transporter
KM400_24135	COG3708	Transcriptional regulator
KM400_24135	COG2207	Transcriptional regulator
KM400_24140	COG0745	RESPONSE REGULATOR receiver
KM400_24145	COG2205	protein histidine kinase activity
KM400_24150	COG0577	efflux transmembrane transporter activity
KM400_24155	COG0577	efflux transmembrane transporter activity
KM400_24160	COG1136	(ABC) transporter
KM400_24180	COG2188	Transcriptional regulator
KM400_24200	COG3964	amidohydrolase
KM400_24230	COG4948	Mandelate Racemase Muconate Lactonizing
KM400_24240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM400_24245	COG0596	Alpha beta hydrolase
KM400_24250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM400_24255	COG1169	isochorismate synthase
KM400_24260	COG1575	Belongs to the MenA family. Type 1 subfamily
KM400_24265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM400_24285	COG0058	SHG alpha-glucan phosphorylase activity
KM400_24290	COG0297	glycogen (starch) synthase activity
KM400_24295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM400_24415	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM400_24450	COG1285	pathogenesis
KM400_24455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM400_24465	COG0166	Belongs to the GPI family
KM400_24470	COG2155	Conserved Protein
KM400_24475	COG1098	S1 RNA binding domain
KM400_24480	COG0436	Aminotransferase
KM400_24485	COG1522	sequence-specific DNA binding
KM400_24490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM400_24495	COG2267	carboxylic ester hydrolase activity
KM400_24505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM400_24525	COG5018	Exonuclease
KM400_24530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM400_24550	COG2050	protein possibly involved in aromatic compounds catabolism
KM400_24560	COG1268	BioY protein
KM400_24570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM400_24575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM400_24590	COG3584	3D domain protein
KM400_24605	COG1252	NADH dehydrogenase
KM400_24620	COG3708	Transcriptional regulator
KM400_24635	COG1683	Conserved Protein
KM400_24655	COG0316	Belongs to the HesB IscA family
KM400_24670	COG1252	NADH dehydrogenase
KM400_24680	COG2274	protein secretion by the type I secretion system
KM400_24685	COG0390	transport system, permease component
KM400_24690	COG2824	Alkylphosphonate utilization operon protein PhnA
KM400_24730	COG4837	Protein of unknown function (DUF1462)
KM400_24735	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM400_24745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM400_24750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM400_24760	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM400_24765	COG0647	UMP catabolic process
KM400_24775	COG2445	Protein of unknown function DUF86
KM400_24780	COG1494	fructose-1,6-bisphosphatase
KM400_24795	COG4470	Protein conserved in bacteria
KM400_24805	COG0789	Transcriptional regulator
KM400_24810	COG4377	Putative membrane peptidase family (DUF2324)
KM400_24835	COG0739	heme binding
KM400_24845	COG3377	Domain of unknown function (DUF1805)
KM400_24850	COG0737	Belongs to the 5'-nucleotidase family
KM400_24855	COG1695	Transcriptional regulator
KM400_24865	COG0719	Fe-S assembly protein
KM400_24870	COG0822	iron-sulfur transferase activity
KM400_24875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM400_24880	COG0719	Fe-S assembly protein
KM400_24885	COG0396	ATPase activity
KM400_24890	COG1464	Belongs to the NlpA lipoprotein family
KM400_24895	COG1464	Belongs to the NlpA lipoprotein family
KM400_24900	COG2011	ABC-type metal ion transport system permease component
KM400_24905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM400_24915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM400_24920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM400_24930	COG1393	Belongs to the ArsC family
KM400_24975	COG0039	L-malate dehydrogenase activity
KM400_24995	COG1309	transcriptional regulator
KM400_25000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM400_25005	COG1960	acyl-CoA dehydrogenase activity
KM400_25010	COG0183	Belongs to the thiolase family
KM400_25015	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM400_25015	COG1024	Enoyl-CoA hydratase
KM400_25025	COG1686	Belongs to the peptidase S11 family
KM400_25040	COG0011	TIGRFAM Protein of
KM400_25045	COG0840	transmembrane signaling receptor activity
KM400_25065	COG2814	Major facilitator Superfamily
KM400_25070	COG0531	amino acid
KM400_25080	COG0706	membrane insertase activity
KM400_25090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM400_25125	COG0586	Pfam SNARE associated Golgi protein
KM400_25135	COG1376	ErfK ybiS ycfS ynhG family protein
KM400_25140	COG0745	RESPONSE REGULATOR receiver
KM400_25145	COG5002	protein histidine kinase activity
KM400_25170	COG2151	metal-sulfur cluster biosynthetic enzyme
KM400_25175	COG3227	Zinc metalloprotease (Elastase)
KM400_25180	COG1741	Belongs to the pirin family
KM400_25195	COG0475	glutathione-regulated potassium exporter activity
KM400_25200	COG0490	domain, Protein
KM400_25205	COG1115	amino acid carrier protein
KM400_25210	COG0783	Belongs to the Dps family
KM400_25225	COG1611	Belongs to the LOG family
KM400_25245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_25250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_25255	COG1115	amino acid carrier protein
KM400_25260	COG1115	amino acid carrier protein
KM400_25265	COG2910	NAD(P)H-binding
KM400_25280	COG0656	L-ascorbic acid biosynthetic process
KM400_25285	COG2814	Major facilitator Superfamily
KM400_25290	COG1733	regulation of RNA biosynthetic process
KM400_25300	COG1252	NADH dehydrogenase
KM400_25305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM400_25310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM400_25320	COG0840	transmembrane signaling receptor activity
KM400_25320	COG3290	protein histidine kinase activity
KM400_25330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM400_25335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM400_25350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM400_25405	COG0557	exoribonuclease II activity
KM400_25410	COG1647	Serine aminopeptidase, S33
KM400_25415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM400_25420	COG1346	cytolysis
KM400_25520	COG4695	Portal protein
KM400_25540	COG4974	Belongs to the 'phage' integrase family
KM400_25555	COG0149	triose-phosphate isomerase activity
KM400_25565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM400_25580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM400_25605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM400_25620	COG2323	membrane
KM400_25625	COG0740	serine-type endopeptidase activity
KM400_25630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM400_25640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM400_25650	COG1051	belongs to the nudix hydrolase family
KM400_25660	COG0492	ferredoxin-NADP+ reductase activity
KM400_25665	COG0457	Tetratricopeptide repeat
KM400_25670	COG0110	maltose O-acetyltransferase activity
KM400_25690	COG1950	PFAM Membrane protein of
KM400_25700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM400_25705	COG0556	nucleotide-excision repair
KM400_25725	COG0789	Transcriptional regulator
KM400_25750	COG2855	membrane
KM400_25755	COG0583	DNA-binding transcription factor activity
KM400_25765	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM400_25770	COG0488	(ABC) transporter
KM400_25780	COG1132	(ABC) transporter
KM400_25785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM400_25790	COG0793	Belongs to the peptidase S41A family
KM400_25790	COG3409	Peptidoglycan-binding domain 1 protein
KM400_25795	COG2177	Part of the ABC transporter FtsEX involved in
KM400_25800	COG2884	Cell division ATP-binding protein ftsE
KM400_25815	COG0653	protein targeting
KM400_25820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM400_25825	COG1278	Cold shock
KM400_25830	COG1040	competence protein
KM400_25835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM400_25840	COG0791	NLP P60 protein
KM400_25840	COG1388	LysM domain
KM400_25845	COG1733	regulation of RNA biosynthetic process
KM400_25850	COG1307	EDD domain protein, DegV family
KM400_25855	COG1739	Uncharacterized protein family UPF0029
KM400_25860	COG1316	TRANSCRIPTIONal
KM400_25865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM400_25870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM400_25875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM400_25885	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM400_25885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM400_25900	COG3394	polysaccharide catabolic process
KM400_25905	COG1486	melibiose metabolic process
KM400_25910	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM400_25915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM400_25925	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM400_25930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM400_25935	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM400_25945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM400_25950	COG1301	dicarboxylic acid transport
KM400_25960	COG0346	lactoylglutathione lyase activity
KM400_25965	COG1511	domain protein
KM400_25970	COG0583	DNA-binding transcription factor activity
KM400_25975	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM400_25990	COG1271	oxidase subunit
KM400_25995	COG1294	oxidase, subunit
KM400_26000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM400_26010	COG1620	l-lactate permease
KM400_26020	COG2389	metal-binding protein
KM400_26030	COG1368	sulfuric ester hydrolase activity
KM400_26045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM400_26055	COG1215	transferase activity, transferring glycosyl groups
KM400_26060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM400_26065	COG1388	LysM domain
KM400_26065	COG3584	3D domain protein
KM400_26090	COG4715	Zinc finger, swim domain protein
KM400_26095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM400_26135	COG0577	efflux transmembrane transporter activity
KM400_26140	COG1136	(ABC) transporter
KM400_26175	COG5002	protein histidine kinase activity
KM400_26180	COG0745	RESPONSE REGULATOR receiver
KM400_26185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM400_26200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM400_26205	COG1134	teichoic acid transport
KM400_26210	COG1682	transport, permease protein
KM400_26215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM400_26260	COG1609	Transcriptional regulator
KM400_26275	COG0739	heme binding
KM400_26295	COG2385	sporulation resulting in formation of a cellular spore
KM400_26310	COG4836	Membrane
KM400_26315	COG1007	ATP synthesis coupled electron transport
KM400_26320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM400_26325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM400_26335	COG0839	Belongs to the complex I subunit 6 family
KM400_26350	COG0649	NAD binding
KM400_26355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM400_26370	COG5001	Diguanylate cyclase
KM400_26370	COG3300	MHYT domain
KM400_26420	COG0356	it plays a direct role in the translocation of protons across the membrane
KM400_26455	COG0698	ribose 5-phosphate isomerase
KM400_26465	COG2190	(PTS) system
KM400_26470	COG2259	Doxx family
KM400_26475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM400_26490	COG0009	L-threonylcarbamoyladenylate synthase
KM400_26505	COG2890	protein-(glutamine-N5) methyltransferase activity
KM400_26525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM400_26530	COG1494	fructose-1,6-bisphosphatase
KM400_26550	COG4821	SIS domain
KM400_26560	COG3343	RNA polymerase activity
KM400_26570	COG1960	acyl-CoA dehydrogenase activity
KM400_26575	COG1960	acyl-CoA dehydrogenase activity
KM400_26580	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM400_26585	COG0183	Belongs to the thiolase family
KM400_26590	COG0247	lactate metabolic process
KM400_26590	COG2181	nitrate reductase activity
KM400_26595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM400_26605	COG5001	Diguanylate cyclase
KM400_26605	COG3300	MHYT domain
KM400_26625	COG2197	response regulator
KM400_26630	COG4585	Histidine kinase
KM400_26635	COG0842	Transport permease protein
KM400_26640	COG1131	(ABC) transporter
KM400_26645	COG0024	Methionine aminopeptidase
KM400_26655	COG2234	aminopeptidase activity
KM400_26675	COG1595	DNA-templated transcription, initiation
KM400_26680	COG0018	arginyl-trna synthetase
KM400_26685	COG4506	Protein conserved in bacteria
KM400_26690	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM400_26705	COG0010	Belongs to the arginase family
KM400_26715	COG2814	Major facilitator Superfamily
KM400_26720	COG0789	Transcriptional regulator
KM400_26725	COG0584	glycerophosphoryl diester phosphodiesterase
KM400_26730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM400_26740	COG1994	Peptidase M50
KM400_26750	COG1078	dGTPase activity
KM400_26755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM400_26760	COG1120	ATPase activity
KM400_26765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM400_26790	COG0095	Lipoate-protein ligase
KM400_26795	COG0280	phosphate acetyltransferase
KM400_26810	COG3773	Cell wall hydrolase
KM400_26820	COG2363	Small membrane protein
KM400_26830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM400_26835	COG2233	PERMEase
KM400_26840	COG0561	phosphatase activity
KM400_26845	COG2814	Major facilitator Superfamily
KM400_26855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM400_26860	COG1131	(ABC) transporter
KM400_26865	COG2755	lipolytic protein G-D-S-L family
KM400_26870	COG1609	Transcriptional regulator
KM400_26880	COG0460	homoserine dehydrogenase
KM400_26890	COG2873	o-acetylhomoserine
KM400_26900	COG1011	Hydrolase
KM400_26905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM400_26915	COG2197	response regulator
KM400_26925	COG0351	phosphomethylpyrimidine kinase
KM400_26930	COG3706	GGDEF domain
KM400_26935	COG2879	small protein
KM400_26940	COG1966	Carbon starvation protein
KM400_26945	COG3279	Response regulator of the LytR AlgR family
KM400_26950	COG0477	Major facilitator Superfamily
KM400_26975	COG0840	transmembrane signaling receptor activity
KM400_26985	COG1607	acyl-coa hydrolase
KM400_27000	COG0488	(ABC) transporter
KM400_27020	COG0463	Glycosyl transferase, family 2
KM400_27025	COG1309	transcriptional regulator
KM400_27030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM400_27035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM400_27035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM400_27040	COG0628	permease
KM400_27055	COG3279	Response regulator of the LytR AlgR family
KM400_27060	COG3275	phosphorelay sensor kinase activity
KM400_27065	COG2814	Major facilitator Superfamily
KM400_27070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM400_27075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM400_27080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM400_27100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM400_27105	COG1272	protein, Hemolysin III
KM400_27130	COG1164	Oligoendopeptidase f
KM400_27150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM400_27155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM400_27160	COG4853	Protein conserved in bacteria
KM400_27165	COG4863	YycH protein
KM400_27170	COG5002	protein histidine kinase activity
KM400_27175	COG0745	RESPONSE REGULATOR receiver
KM400_27205	COG0305	Participates in initiation and elongation during chromosome replication
KM400_27215	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM400_27220	COG4241	membrane
KM400_27230	COG0629	single-stranded DNA binding
KM400_27240	COG0012	GTP binding
KM400_27245	COG4481	Protein conserved in bacteria
KM400_27250	COG0668	transmembrane transport
KM400_27260	COG1475	DNA binding
KM400_27265	COG1192	Involved in chromosome partitioning
KM400_27290	COG1847	R3H domain protein
KM400_27295	COG0706	membrane insertase activity
KM400_27305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM400_27360	COG3344	reverse transcriptase
KM400_27440	COG3344	reverse transcriptase
KM400_27635	COG4962	Type ii secretion system protein e
KM400_27775	COG2311	Membrane
KM400_27795	COG4196	transglutaminase domain protein
KM400_27800	COG0671	phosphoesterase, PA-phosphatase related
KM400_27815	COG1215	transferase activity, transferring glycosyl groups
KM400_27820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM400_27825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM400_27990	COG2002	toxin-antitoxin pair type II binding
KM400_28000	COG4974	Belongs to the 'phage' integrase family
KM400_28055	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM400_28065	COG4974	Belongs to the 'phage' integrase family
KM400_28090	COG0457	Tetratricopeptide repeat
KM400_28360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM400_28365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM400_28420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM400_28430	COG4166	transmembrane transport
KM400_28465	COG1280	lysine exporter protein (LysE YggA)
KM400_28490	COG0681	Belongs to the peptidase S26 family
KM400_28565	COG1309	transcriptional regulator
KM400_28570	COG1683	Conserved Protein
KM400_28615	COG1192	Involved in chromosome partitioning