locus-tag class description BAMEG_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAMEG_0003 ENOG410848D S4 domain protein YaaA BAMEG_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAMEG_0014 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAMEG_0021 ENOG4105ZMH deoxynucleoside kinase BAMEG_0023 ENOG4105GTG Isochorismatase BAMEG_0024 ENOG4108Z6B deaminase BAMEG_0026 ENOG4105C6E dna polymerase iii BAMEG_0030 ENOG41067KS pro-sigma K processing BAMEG_0038 ENOG4105CXN decarboxylase BAMEG_0040 ENOG4105FA2 dna polymerase iii BAMEG_0041 ENOG4105MA4 psp1 domain protein BAMEG_0043 ENOG41060K3 Methyltransferase BAMEG_0045 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAMEG_0046 ENOG4105KRN Transcriptional regulator, abrb family BAMEG_0048 ENOG4105F8V Hydrolase, tatD family BAMEG_0049 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BAMEG_0051 ENOG4105XFA sporulation peptidase YabG BAMEG_0052 ENOG4105W42 Veg protein BAMEG_0055 ENOG4105DFT pur operon repressor BAMEG_0057 ENOG4105KME endoribonuclease L-psp BAMEG_0060 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAMEG_0061 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BAMEG_0063 ENOG4108JA2 transcriptioN-repair coupling factor BAMEG_0064 ENOG4108M14 stage v sporulation protein t BAMEG_0066 ENOG4108IY2 MazG family BAMEG_0067 ENOG41082I2 s4 domain protein BAMEG_0068 ENOG4105VYY sporulation protein yabp BAMEG_0071 ENOG41060GV RNA binding s1 domain protein BAMEG_0075 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAMEG_0076 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAMEG_0077 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAMEG_0080 ENOG4105C6T cysteine synthase BAMEG_0081 ENOG4105CRQ synthase (Component I) BAMEG_0082 ENOG4105DDQ anthranilate synthase BAMEG_0083 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAMEG_0084 ENOG4105EEI dihydropteroate synthase BAMEG_0085 ENOG4105KRF dihydroneopterin aldolase BAMEG_0086 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAMEG_0088 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAMEG_0095 ENOG4108Z0C Uvrb UvrC protein BAMEG_0098 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAMEG_0100 ENOG4105CTP PilT protein domain protein BAMEG_0104 ENOG4105D7W serine acetyltransferase BAMEG_0107 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAMEG_0108 ENOG4105M0M Tetracycline resistance protein BAMEG_0109 ENOG4105QIV RNA polymerase BAMEG_0111 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAMEG_0117 ENOG4107Y49 methyltransferase BAMEG_0119 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAMEG_0120 ENOG4105XPM ribosomal protein BAMEG_0141 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAMEG_0146 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAMEG_0148 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAMEG_0150 ENOG41067V7 50S ribosomal protein L36 BAMEG_0156 ENOG4108JJB ABC transporter BAMEG_0157 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAMEG_0158 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAMEG_0164 ENOG4105D1F ATP-binding protein BAMEG_0167 ENOG4108NMV polysaccharide deacetylase BAMEG_0185 ENOG4105C8B TIGR00159 family BAMEG_0186 ENOG4107U5W ybbr family BAMEG_0189 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BAMEG_0190 ENOG4108VQT Alpha beta hydrolase fold protein BAMEG_0192 ENOG4105CMG Carbohydrate kinase BAMEG_0193 ENOG4105CMG Carbohydrate kinase BAMEG_0195 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAMEG_0196 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAMEG_0204 ENOG4108PSK reductase BAMEG_0205 ENOG4108UMI ABC transporter, permease BAMEG_0206 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_0207 ENOG4105D01 (LipO)protein BAMEG_0209 ENOG4105EE1 crotonyl-CoA reductase BAMEG_0211 ENOG4105IQ5 FAD linked oxidase domain protein BAMEG_0214 ENOG4105C2C drug resistance transporter, Bcr CflA BAMEG_0218 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAMEG_0219 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAMEG_0220 ENOG4105C3U ABC transporter BAMEG_0221 ENOG4108JQ7 (ABC) transporter BAMEG_0227 ENOG4108J59 Extracellular solute-binding protein, family 5 BAMEG_0228 ENOG4108J59 Extracellular solute-binding protein, family 5 BAMEG_0231 ENOG4105II7 pyrroline-5-carboxylate reductase BAMEG_0232 ENOG4107XDY Nicotinamide Mononucleotide Transporter BAMEG_0234 ENOG4105E0C molybdate abc transporter BAMEG_0235 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAMEG_0236 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAMEG_0237 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAMEG_0238 ENOG4105EGI Transcriptional regulator BAMEG_0241 ENOG4105F6E Acyl-transferase BAMEG_0244 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAMEG_0247 ENOG4108RE7 deoxyribonuclease BAMEG_0248 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAMEG_0254 ENOG4105C5H ABC transporter BAMEG_0257 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BAMEG_0259 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAMEG_0260 ENOG4105C3U ABC transporter BAMEG_0261 ENOG4108JQ7 (ABC) transporter BAMEG_0262 ENOG410667J hydrolase BAMEG_0269 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BAMEG_0270 ENOG4105ERH Fumarylacetoacetate hydrolase BAMEG_0272 ENOG4108SC4 )-transporter BAMEG_0273 ENOG4105CPF Cell wall formation (By similarity) BAMEG_0274 ENOG4105CPF Cell wall formation (By similarity) BAMEG_0275 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAMEG_0277 ENOG4107ZXI Rhomboid family BAMEG_0280 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAMEG_0281 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAMEG_0283 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAMEG_0303 ENOG4105K8N protein family UPF0079, ATPase BAMEG_0304 ENOG41072GX Peptidase M22 Glycoprotease BAMEG_0305 ENOG410801F ribosomal-protein-alanine acetyltransferase BAMEG_0306 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAMEG_0307 ENOG4105C5H ABC transporter BAMEG_0310 ENOG4108TYN CAAX amino terminal protease family protein BAMEG_0316 ENOG4105C7N Xanthine uracil vitamin C permease BAMEG_0318 ENOG4105BZU Histidine kinase BAMEG_0325 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAMEG_0330 ENOG4108SHN Glycosyl transferase, family 2 BAMEG_0336 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAMEG_0340 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_0346 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAMEG_0347 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAMEG_0348 ENOG4105C83 adenylosuccinate lyase BAMEG_0350 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAMEG_0355 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAMEG_0357 ENOG4105C12 Phosphoribosylglycinamide synthetase BAMEG_0362 ENOG4105C4R Atp-dependent dna helicase BAMEG_0368 ENOG4108W2Y isochorismatase BAMEG_0370 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_0371 ENOG4108UMI ABC transporter, permease BAMEG_0372 ENOG4105D01 (LipO)protein BAMEG_0376 ENOG4105D0U Arsenite-activated ATPase (ArsA) BAMEG_0377 ENOG410834F Transcriptional regulator BAMEG_0378 ENOG4107I77 yiaA/B two helix domain BAMEG_0382 ENOG4105CBD Diacylglycerol kinase BAMEG_0383 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAMEG_0384 ENOG4108JPW Aminotransferase BAMEG_0386 ENOG4105C26 Dehydrogenase BAMEG_0387 ENOG4105KPY Small multidrug resistance protein BAMEG_0391 ENOG4105D9N nucleoside BAMEG_0393 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAMEG_0396 ENOG4108W15 Protein of unknown function (DUF1456) BAMEG_0399 ENOG4105DTQ mandelate racemase muconate lactonizing BAMEG_0400 ENOG4105DFD Na H antiporter BAMEG_0405 ENOG4105D3R alkyl hydroperoxide reductase BAMEG_0406 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BAMEG_0408 ENOG4107W7X Aldolase BAMEG_0409 ENOG4105EHG Permease protein BAMEG_0410 ENOG4105DQ5 transport system permease protein BAMEG_0411 ENOG4108V5C ABC transporter BAMEG_0415 ENOG4106UIA BAMEG_0421 ENOG4105BZU Histidine kinase BAMEG_0426 ENOG410756H nucleotidyltransferase BAMEG_0427 ENOG4105D2S major facilitator superfamily BAMEG_0430 ENOG4105E5Q amino acid AbC transporter BAMEG_0431 ENOG4105EAB amino acid AbC transporter BAMEG_0433 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_0434 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_0436 ENOG4105CI1 PTS System BAMEG_0444 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAMEG_0448 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAMEG_0452 ENOG4105C5H ABC transporter BAMEG_0457 ENOG41062JF Transcriptional regulator BAMEG_0461 ENOG4105DEU major facilitator superfamily BAMEG_0464 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BAMEG_0467 ENOG4108N0M stress protein BAMEG_0468 ENOG4106FN3 tellurium resistance protein BAMEG_0469 ENOG4106FN3 tellurium resistance protein BAMEG_0470 ENOG4107TS3 membrane protein, TerC BAMEG_0471 ENOG4108TTB tellurium resistance protein BAMEG_0476 ENOG4105KJF protein tyrosine phosphatase BAMEG_0478 ENOG4107U9T Pfam:Ribonuclease_BN BAMEG_0479 ENOG4105C59 p-type ATPase BAMEG_0480 ENOG4108IPJ Membrane BAMEG_0482 ENOG4105C3F Signal peptidase i BAMEG_0485 ENOG4107ZTW SNARE associated Golgi BAMEG_0489 ENOG410606W general stress protein BAMEG_0490 ENOG4105UPD Calcium Proton BAMEG_0498 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAMEG_0499 ENOG4105VTR Integrase BAMEG_0515 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_0518 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAMEG_0535 ENOG4105CAR Terminase, large subunit BAMEG_0537 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAMEG_0554 ENOG4105XSJ toxin secretion phage lysis holin BAMEG_0564 ENOG4105KNH Nucleic acid-binding protein BAMEG_0571 ENOG41068DC Essential cell division protein (By similarity) BAMEG_0572 ENOG4105CJN penicillin-binding protein BAMEG_0573 ENOG4105CJN penicillin-binding protein BAMEG_0574 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAMEG_0577 ENOG4105CNI cell division protein FtsW BAMEG_0578 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAMEG_0579 ENOG4105D4A Cell wall formation (By similarity) BAMEG_0580 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAMEG_0581 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAMEG_0582 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAMEG_0584 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_0586 ENOG4105WR5 sporulation protein, YlmC YmxH family BAMEG_0587 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAMEG_0588 ENOG4105DFA alanine racemase domain protein BAMEG_0590 ENOG41067XK integral membrane protein BAMEG_0591 ENOG4105DBK s4 domain protein BAMEG_0593 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAMEG_0596 ENOG4105C34 Pseudouridine synthase BAMEG_0597 ENOG4105C34 Pseudouridine synthase BAMEG_0605 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAMEG_0616 ENOG4105DC7 peptidase M24 BAMEG_0618 ENOG4105F23 Fibronectin-binding protein BAMEG_0620 ENOG4105DSJ YicC domain protein BAMEG_0624 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAMEG_0625 ENOG4105C25 Primosomal protein n' BAMEG_0626 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAMEG_0628 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAMEG_0630 ENOG4108ZF3 Phosphatase BAMEG_0631 ENOG4105D9P serine threonine protein kinase BAMEG_0632 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAMEG_0633 ENOG4105DJV ribulose-phosphate 3-epimerase BAMEG_0634 ENOG4105FJ0 thiamine BAMEG_0636 ENOG4108ZAA Alkaline-shock protein BAMEG_0637 ENOG4105DP4 dak2 domain fusion protein ylov BAMEG_0638 ENOG4105CB5 ATP-dependent DNA helicase recG BAMEG_0641 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAMEG_0642 ENOG4105CHR reductase BAMEG_0645 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAMEG_0646 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAMEG_0650 ENOG4105VB6 UPF0109 protein BAMEG_0656 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAMEG_0659 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAMEG_0661 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAMEG_0663 ENOG4108HE4 integrase family BAMEG_0671 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BAMEG_0672 ENOG4105KNE Phosphatidate cytidylyltransferase BAMEG_0673 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAMEG_0674 ENOG4105DZP Membrane-associated zinc metalloprotease BAMEG_0676 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAMEG_0678 ENOG4105CHV Transcription elongation factor NusA BAMEG_0679 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAMEG_0680 ENOG4105VHM ribosomal protein BAMEG_0682 ENOG4105W7A Protein of unknown function (DUF503) BAMEG_0684 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAMEG_0685 ENOG4105DTN riboflavin biosynthesis protein ribF BAMEG_0689 ENOG4105C1V Peptidase, M16 BAMEG_0691 ENOG4105E35 Dipicolinate synthase subunit A BAMEG_0692 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAMEG_0693 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAMEG_0695 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAMEG_0697 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAMEG_0699 ENOG4107QZI cell division protein FtsK BAMEG_0701 ENOG4105FDP GntR family transcriptional regulator BAMEG_0702 ENOG4105DIH basic membrane BAMEG_0703 ENOG4108JQ9 ABC transporter BAMEG_0704 ENOG4105UIB (ABC) transporter BAMEG_0705 ENOG4105UIB (ABC) transporter BAMEG_0709 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAMEG_0710 ENOG4105XZV Protein of unknown function (DUF3243) BAMEG_0713 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAMEG_0718 ENOG4105D48 metallophosphoesterase BAMEG_0719 ENOG4105MCT stage V sporulation protein S BAMEG_0720 ENOG4108IGT Dipeptidase BAMEG_0721 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BAMEG_0722 ENOG4105DQU oxidoreductase, subunit beta BAMEG_0723 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAMEG_0728 ENOG4105DA5 (ABC) transporter BAMEG_0733 ENOG4107QHE Choloylglycine hydrolase BAMEG_0735 ENOG410890F Dynamin family BAMEG_0736 ENOG4105E0M Sulfatase BAMEG_0737 ENOG4107R6R udp-galactopyranose mutase BAMEG_0738 ENOG4105F0V Cell wall hydrolase BAMEG_0743 ENOG4107YEI lmbE family BAMEG_0744 ENOG4107TTQ Alpha beta hydrolase fold BAMEG_0747 ENOG41067MG lrgb family BAMEG_0751 ENOG4105BZU Histidine kinase BAMEG_0753 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_0760 ENOG4105D03 DNA-3-methyladenine glycosylase II BAMEG_0761 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAMEG_0763 ENOG4105CGK Exodeoxyribonuclease III BAMEG_0768 ENOG4105E0A ABC, transporter BAMEG_0769 ENOG4105NIV Esterase BAMEG_0771 ENOG4105VPX protein, conserved in bacteria BAMEG_0772 ENOG410681U heavy metal transport detoxification protein BAMEG_0773 ENOG4105C59 p-type ATPase BAMEG_0774 ENOG4105K70 DNA-binding protein BAMEG_0775 ENOG4105TMB Formate nitrite transporter BAMEG_0779 ENOG4105C85 amino acid BAMEG_0782 ENOG4108SJC Membrane BAMEG_0783 ENOG4107QW4 alcohol dehydrogenase BAMEG_0784 ENOG4107QW4 alcohol dehydrogenase BAMEG_0785 ENOG4105E98 transcriptional regulator DeoR family BAMEG_0786 ENOG4105DE4 1-phosphofructokinase BAMEG_0787 ENOG4105DM4 PTS System BAMEG_0788 ENOG41069ER domain protein BAMEG_0794 ENOG4106F1P AAA ATPase, central domain protein BAMEG_0795 ENOG4105EN6 Membrane BAMEG_0796 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAMEG_0797 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAMEG_0798 ENOG4105CXI aluminum resistance protein BAMEG_0799 ENOG4105KV4 Transcriptional regulator BAMEG_0800 ENOG4105C5F glutamine synthetase BAMEG_0822 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BAMEG_0867 ENOG4105XSJ toxin secretion phage lysis holin BAMEG_0868 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAMEG_0878 ENOG4105K7K Transcriptional regulator BAMEG_0882 ENOG4108SVB resolvase BAMEG_0884 ENOG4105CGH 5'-nucleotidase BAMEG_0887 ENOG4105D5T phosphonate abc transporter BAMEG_0890 ENOG4105D7V transposase BAMEG_0894 ENOG4105BZ1 (ABC) transporter BAMEG_0895 ENOG4105BZ1 (ABC) transporter BAMEG_0898 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAMEG_0904 ENOG41067MG lrgb family BAMEG_0905 ENOG4105VAW lrga family BAMEG_0906 ENOG4107RSM transcriptional regulator BAMEG_0908 ENOG4107QIV Cytochrome c biogenesis protein BAMEG_0920 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BAMEG_0925 ENOG4108903 Formimidoylglutamase BAMEG_0926 ENOG4108VJ1 Transcriptional regulator (CarD family BAMEG_0927 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAMEG_0928 ENOG4105CBC glutamate synthase BAMEG_0929 ENOG4105CK7 Sodium proline symporter BAMEG_0930 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAMEG_0931 ENOG4105FBA Phospholipase Carboxylesterase BAMEG_0932 ENOG4105BZU Histidine kinase BAMEG_0934 ENOG4107AYK membrAne BAMEG_0943 ENOG4105CEY Amp-dependent synthetase and ligase BAMEG_0944 ENOG4107ZYJ bioY protein BAMEG_0945 ENOG4107F3J Amp-dependent synthetase and ligase BAMEG_0949 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAMEG_0951 ENOG4105E5W Transporter BAMEG_0957 ENOG4108I0Z Aconitate hydratase BAMEG_0958 ENOG4108JJA ABC, transporter BAMEG_0961 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAMEG_0962 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAMEG_0968 ENOG4105W8X HesB YadR YfhF-family protein BAMEG_0969 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAMEG_0970 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BAMEG_0972 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_0973 ENOG4105C0H protease BAMEG_0974 ENOG4105K4P CoA-binding domain protein BAMEG_0975 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAMEG_0977 ENOG4105D9R oxidoreductase BAMEG_0979 ENOG4105CIG ABC transporter BAMEG_0984 ENOG4105EMN RNA polymerase sigma factor BAMEG_0986 ENOG4108KGH TRANSCRIPTIONal BAMEG_0987 ENOG4107QJT sodium dicarboxylate symporter BAMEG_1001 ENOG4105E1K spore germination protein BAMEG_1002 ENOG4108JB9 formate dehydrogenase BAMEG_1004 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAMEG_1005 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAMEG_1007 ENOG4105TMB Formate nitrite transporter BAMEG_1008 ENOG4105D06 uba thif-type nad fad binding protein BAMEG_1009 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAMEG_1010 ENOG4108ZAF Molybdopterin BAMEG_1012 ENOG4105D1F ATP-binding protein BAMEG_1015 ENOG410696E Membrane BAMEG_1016 ENOG4105FR1 rard protein BAMEG_1018 ENOG4105EWU Squalene--hopene cyclase BAMEG_1020 ENOG4105CHR reductase BAMEG_1021 ENOG4105C26 Dehydrogenase BAMEG_1023 ENOG4108IA2 Sodium pantothenate symporter BAMEG_1028 ENOG4106IQC argininosuccinate lyase BAMEG_1030 ENOG410904N short-chain dehydrogenase reductase BAMEG_1034 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BAMEG_1038 ENOG4105VEQ Cold shock protein BAMEG_1042 ENOG4108R1P BAMEG_1044 ENOG41073R8 VanW family BAMEG_1045 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_1048 ENOG4105KT7 mgtC SapB transporter BAMEG_1050 ENOG4105E39 Enoyl-CoA hydratase BAMEG_1051 ENOG4105K64 Glycosyl transferase, family 2 BAMEG_1053 ENOG4108UT6 Transferase hexapeptide repeat containing protein BAMEG_1057 ENOG4105CQB FAD linked oxidase domain protein BAMEG_1058 ENOG4105C09 Bile acid BAMEG_1060 ENOG4105RHY Pfam:UPF0157 BAMEG_1066 ENOG4105CIS alcohol dehydrogenase BAMEG_1067 ENOG41082BM Transcriptional regulator, arsr family BAMEG_1071 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAMEG_1077 ENOG4108A04 Beta-lactamase BAMEG_1078 ENOG4105DPN Oligoendopeptidase f BAMEG_1079 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAMEG_1080 ENOG4105E5K Alpha-amylase BAMEG_1083 ENOG4105C98 muts2 protein BAMEG_1087 ENOG4107V2S Transcriptional regulator BAMEG_1089 ENOG4107CUJ Protein of unknown function (DUF2690) BAMEG_1093 ENOG4107ZY0 Phenazine biosynthesis-like protein BAMEG_1094 ENOG4105NX3 Membrane BAMEG_1095 ENOG4105DQ5 transport system permease protein BAMEG_1096 ENOG4105EHG Permease protein BAMEG_1098 ENOG4108MES Periplasmic binding protein BAMEG_1103 ENOG4107R3E Citrate transporter BAMEG_1105 ENOG4108TN2 lmbE family BAMEG_1113 ENOG4105CIS alcohol dehydrogenase BAMEG_1120 ENOG4105H3G oxidoreductase BAMEG_1122 ENOG4105ED2 Beta-lactamase BAMEG_1127 ENOG4107YXZ hydrolase, family 25 BAMEG_1130 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BAMEG_1146 ENOG4108ZJ4 polysaccharide deacetylase BAMEG_1151 ENOG4105KVH Transcriptional regulator BAMEG_1152 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAMEG_1156 ENOG4105CHR reductase BAMEG_1158 ENOG4105JAB phenazine biosynthesis protein, phzf family BAMEG_1165 ENOG4105KVH Transcriptional regulator BAMEG_1166 ENOG4105KVH Transcriptional regulator BAMEG_1167 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BAMEG_1169 ENOG4105D9R oxidoreductase BAMEG_1171 ENOG4108TZY GntR Family Transcriptional Regulator BAMEG_1172 ENOG4105KVH Transcriptional regulator BAMEG_1178 ENOG4105C44 Serine transporter BAMEG_1179 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAMEG_1182 ENOG4105F27 Major Facilitator BAMEG_1183 ENOG4105CV8 reductase BAMEG_1187 ENOG4105D4Y metalloprotease BAMEG_1188 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAMEG_1191 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BAMEG_1192 ENOG4105CIS alcohol dehydrogenase BAMEG_1193 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAMEG_1194 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAMEG_1197 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAMEG_1198 ENOG4105C6Z Gluconate BAMEG_1199 ENOG4105CMG Carbohydrate kinase BAMEG_1200 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAMEG_1201 ENOG4105XDF Protein of unknown function (DUF1272) BAMEG_1202 ENOG4105DDN Pentapeptide repeat-containing protein BAMEG_1205 ENOG4105C37 (CBS) domain BAMEG_1211 ENOG4105EV4 Multidrug resistance protein mdtH BAMEG_1213 ENOG4105DMQ Methyltransferase BAMEG_1219 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAMEG_1220 ENOG4105C31 Tryptophanyl-tRNA synthetase BAMEG_1222 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAMEG_1224 ENOG4108UW5 maltose o-acetyltransferase BAMEG_1225 ENOG4106UW1 Major Facilitator superfamily BAMEG_1226 ENOG4105DKQ ROK family BAMEG_1227 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_1239 ENOG4105CJ1 ABC, transporter BAMEG_1241 ENOG4108PSK reductase BAMEG_1245 ENOG4108RCM Nitroreductase BAMEG_1246 ENOG4105KVH Transcriptional regulator BAMEG_1249 ENOG4105CUT histidyl-tRNA synthetase BAMEG_1250 ENOG4108Z66 YbaK ebsC protein BAMEG_1252 ENOG41067QW Transcriptional regulator BAMEG_1255 ENOG4108K8S endonuclease I BAMEG_1260 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAMEG_1261 ENOG4108JJB ABC transporter BAMEG_1268 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAMEG_1270 ENOG4105CRW Short chain fatty acid transporter BAMEG_1272 ENOG4105KBX Transcriptional regulator, TetR family BAMEG_1273 ENOG4105KPY Small multidrug resistance protein BAMEG_1274 ENOG4105RXJ BAMEG_1277 ENOG41069JR BAMEG_1278 ENOG4105DA5 (ABC) transporter BAMEG_1282 ENOG4105CZM Major Facilitator BAMEG_1283 ENOG4107MII Sugar-specific transcriptional regulator TrmB BAMEG_1285 ENOG4108ISG Major Facilitator BAMEG_1293 ENOG4105HIR S-layer domain protein BAMEG_1297 ENOG410874W AraC family transcriptional regulator BAMEG_1298 ENOG41082W1 Cupin 2, conserved barrel domain protein BAMEG_1301 ENOG4108AEY RNA polymerase sigma factor BAMEG_1305 ENOG4108JQ1 Dehydrogenase BAMEG_1308 ENOG4105DVH amino acid BAMEG_1310 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BAMEG_1313 ENOG4108JPW Aminotransferase BAMEG_1316 ENOG4105EJQ L-serine dehydratase BAMEG_1317 ENOG4105C44 Serine transporter BAMEG_1319 ENOG4108JGH Tetr family transcriptional regulator BAMEG_1320 ENOG4105EQ0 Major Facilitator superfamily BAMEG_1321 ENOG4105MZU cell filamentation protein BAMEG_1324 ENOG4107QJQ Mate efflux family protein BAMEG_1329 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_1332 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAMEG_1340 ENOG4105TRI Hydrolase BAMEG_1345 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAMEG_1347 ENOG4106P55 Transcriptional regulator BAMEG_1349 ENOG4107QR9 Iron-sulfur cluster binding protein BAMEG_1350 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BAMEG_1351 ENOG4105DJB Major Facilitator Superfamily BAMEG_1352 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAMEG_1354 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAMEG_1355 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAMEG_1356 ENOG4108U05 Transcriptional regulator BAMEG_1359 ENOG4105BZU Histidine kinase BAMEG_1362 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BAMEG_1363 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAMEG_1366 ENOG4105JQZ Methyltransferase BAMEG_1367 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAMEG_1369 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAMEG_1370 ENOG4108NNI Beta-lactamase domain-containing protein BAMEG_1373 ENOG4105VZ8 Transcriptional regulator BAMEG_1379 ENOG4105K6H D-cysteine desulfhydrase BAMEG_1384 ENOG41062D9 Histidine kinase BAMEG_1385 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_1388 ENOG4105IIP Membrane BAMEG_1390 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_1392 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAMEG_1407 ENOG4108YXU transcriptional regulator AsnC family BAMEG_1408 ENOG4105CHR reductase BAMEG_1410 ENOG4105F7F Chaperone BAMEG_1413 ENOG41085FC arsR family transcriptional regulator BAMEG_1414 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_1415 ENOG4105D6J arsenicaL-resistance protein BAMEG_1421 ENOG4105DIK (ABC) transporter BAMEG_1422 ENOG4105CC5 ABC transporter BAMEG_1423 ENOG4105DSE periplasmic solute binding protein BAMEG_1424 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BAMEG_1425 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAMEG_1427 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BAMEG_1428 ENOG4108TWJ NADH dehydrogenase subunit 5 BAMEG_1431 ENOG4105CVP deoxyribo-dipyrimidine photolyase BAMEG_1432 ENOG4108606 TspO/MBR family BAMEG_1440 ENOG41090MY MarR family Transcriptional regulator BAMEG_1445 ENOG4105CHJ isochorismatase hydrolase BAMEG_1447 ENOG4105CH6 catalase BAMEG_1448 ENOG4105CGH 5'-nucleotidase BAMEG_1455 ENOG4105CSV Glutaminase BAMEG_1462 ENOG4108Q8B Spore germination protein BAMEG_1463 ENOG4108NHD germination protein BAMEG_1464 ENOG4108NHD germination protein BAMEG_1466 ENOG4105C6K Malic enzyme BAMEG_1469 ENOG4105II7 pyrroline-5-carboxylate reductase BAMEG_1471 ENOG4105CUB amino acid BAMEG_1472 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAMEG_1474 ENOG4108IMY Transcriptional regulator BAMEG_1475 ENOG4105HDK L-asparaginase BAMEG_1476 ENOG4108IJ0 Aspartate ammonia-lyase BAMEG_1479 ENOG4105E2A Dehydrogenase BAMEG_1494 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAMEG_1500 ENOG4105DWD nucleoside recognition domain protein BAMEG_1504 ENOG4105FDT acyl-CoA dehydrogenase BAMEG_1506 ENOG4108ZHR arsR family transcriptional regulator BAMEG_1507 ENOG4108ZRV stage ii sporulation protein p BAMEG_1508 ENOG4106N3A copper homeostasis protein cutc BAMEG_1510 ENOG4107258 Transcriptional regulator BAMEG_1511 ENOG4105P4J Allophanate hydrolase, subunit 1 BAMEG_1518 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAMEG_1520 ENOG4107RF6 penicillin-binding protein BAMEG_1528 ENOG4105F1N DNA alkylation repair BAMEG_1530 ENOG4108IQI permease BAMEG_1532 ENOG4105KNA -acetyltransferase BAMEG_1533 ENOG410635A Membrane BAMEG_1550 ENOG4108XET gCN5-related N-acetyltransferase BAMEG_1556 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BAMEG_1558 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAMEG_1567 ENOG4105FS7 Transcriptional regulator BAMEG_1568 ENOG4108TVJ Nitroreductase BAMEG_1570 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAMEG_1579 ENOG4105C8Y Acetylornithine aminotransferase BAMEG_1581 ENOG4105CKK Glycosyl transferase, family 2 BAMEG_1585 ENOG4105CKK Glycosyl transferase, family 2 BAMEG_1589 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAMEG_1595 ENOG41068WN BAMEG_1597 ENOG4108WCX response regulator BAMEG_1599 ENOG41090T1 Membrane BAMEG_1602 ENOG4105VMP Transcriptional regulator BAMEG_1604 ENOG4105G6Z alkaline phosphatase BAMEG_1605 ENOG4105ECK Fatty Acid Desaturase BAMEG_1606 ENOG4105E0Y RtcB Protein BAMEG_1608 ENOG4107258 Transcriptional regulator BAMEG_1610 ENOG4105II7 pyrroline-5-carboxylate reductase BAMEG_1611 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAMEG_1617 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAMEG_1621 ENOG41061GT Aldolase BAMEG_1624 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BAMEG_1625 ENOG4105DKT Transcriptional regulator BAMEG_1628 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BAMEG_1630 ENOG4105D4B ABC, transporter BAMEG_1635 ENOG4105EMN RNA polymerase sigma factor BAMEG_1637 ENOG41069ER domain protein BAMEG_1645 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAMEG_1646 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAMEG_1647 ENOG4105CIH Imidazole acetol-phosphate transaminase BAMEG_1651 ENOG41082JN Transcriptional regulator BAMEG_1652 ENOG4105EYF MMPL domain protein BAMEG_1653 ENOG4105EYF MMPL domain protein BAMEG_1654 ENOG4105EYF MMPL domain protein BAMEG_1656 ENOG4105C5H ABC transporter BAMEG_1657 ENOG4105E0M Sulfatase BAMEG_1658 ENOG4108ZCF integral membrane protein BAMEG_1660 ENOG4107VMI polysaccharide deacetylase BAMEG_1663 ENOG4107VC0 DNA alkylation repair enzyme BAMEG_1674 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BAMEG_1678 ENOG4105E09 nadh pyrophosphatase BAMEG_1683 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAMEG_1684 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAMEG_1685 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BAMEG_1687 ENOG4105C02 permease BAMEG_1695 ENOG4105DVE abc transporter atp-binding protein BAMEG_1701 ENOG4105CHM Aminotransferase BAMEG_1709 ENOG41089UC methyltransferase, type 11 BAMEG_1712 ENOG4107BMA Transglycosylase associated protein BAMEG_1717 ENOG4106K7D Major facilitator family transporter BAMEG_1718 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAMEG_1726 ENOG4105EPR degv family BAMEG_1729 ENOG4105DPN Oligoendopeptidase f BAMEG_1736 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_1737 ENOG4105BZU Histidine kinase BAMEG_1738 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BAMEG_1746 ENOG4105DTQ mandelate racemase muconate lactonizing BAMEG_1749 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAMEG_1750 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAMEG_1753 ENOG4107T5V SNARE associated Golgi BAMEG_1761 ENOG41080HI glycine oxidase BAMEG_1762 ENOG4105CTU Proline racemase BAMEG_1763 ENOG4105CTU Proline racemase BAMEG_1764 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAMEG_1765 ENOG4105C26 Dehydrogenase BAMEG_1766 ENOG4105BZG amino acid carrier protein BAMEG_1769 ENOG4108M1A Chitin-binding protein BAMEG_1778 ENOG4105C9U ATP-dependent DNA helicase RecQ BAMEG_1782 ENOG4105EEM helicase BAMEG_1786 ENOG4108Z7F N-acetyltransferase BAMEG_1792 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAMEG_1802 ENOG4108M1A Chitin-binding protein BAMEG_1804 ENOG41082BV acetyltransferase BAMEG_1805 ENOG4105E66 phosphoriboisomerase A BAMEG_1810 ENOG4108IJ7 Glycine betaine BAMEG_1811 ENOG4107SQ8 Glycine betaine BAMEG_1816 ENOG4105RHY Pfam:UPF0157 BAMEG_1817 ENOG4105E1F short-chain dehydrogenase reductase BAMEG_1820 ENOG4107RUY (E1 component), alpha subunit BAMEG_1822 ENOG4107QKR Dehydrogenase BAMEG_1827 ENOG41062ES Transcriptional regulator BAMEG_1831 ENOG4105E98 transcriptional regulator DeoR family BAMEG_1835 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAMEG_1841 ENOG4107Z3H Transcriptional regulator, TetR family BAMEG_1842 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BAMEG_1843 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BAMEG_1844 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BAMEG_1848 ENOG4105MSI germination protein ypeb BAMEG_1852 ENOG4108V3A UPF0421 protein BAMEG_1859 ENOG4105FDR Membrane BAMEG_1861 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAMEG_1867 ENOG4108IUM Glycogen debranching enzyme BAMEG_1870 ENOG4105DY8 decarboxylase BAMEG_1875 ENOG4105PAD Hydrolase BAMEG_1880 ENOG4107VFR oxidoreductase BAMEG_1889 ENOG4105PKS Excinuclease abc c subunit domain protein BAMEG_1896 ENOG4105KWG Pfam:DUF1696 BAMEG_1902 ENOG4108XI2 Domain of unknown function (DUF1963) BAMEG_1909 ENOG4108Z4K mutator MutT protein BAMEG_1910 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAMEG_1911 ENOG4105E09 nadh pyrophosphatase BAMEG_1913 ENOG4105FCD Major Facilitator BAMEG_1921 ENOG4107Y9U Membrane BAMEG_1927 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAMEG_1930 ENOG4107Y80 Major Facilitator superfamily BAMEG_1935 ENOG4108V4B ThiJ pfpI BAMEG_1941 ENOG4105FQP Beta-lactamase BAMEG_1943 ENOG4105CJN penicillin-binding protein BAMEG_1944 ENOG4105CB2 alcohol dehydrogenase BAMEG_1947 ENOG4108HGU Histidine kinase BAMEG_1950 ENOG4108JJB ABC transporter BAMEG_1955 ENOG4107RF6 penicillin-binding protein BAMEG_1956 ENOG4105BZU Histidine kinase BAMEG_1958 ENOG410667J hydrolase BAMEG_1983 ENOG4105ETU transcriptional activator (TenA BAMEG_2005 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAMEG_2006 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAMEG_2009 ENOG4105CPQ Dehydrogenase BAMEG_2016 ENOG4105CUV Homoserine Kinase BAMEG_2020 ENOG4107Y80 Major Facilitator superfamily BAMEG_2022 ENOG4105FQP Beta-lactamase BAMEG_2025 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAMEG_2025 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAMEG_2036 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BAMEG_2038 ENOG4105T9C HD domain BAMEG_2041 ENOG4105DZ1 carboxypeptidase BAMEG_2044 ENOG4105DBI uridine monophosphokinase BAMEG_2045 ENOG4105WCN acetyltransferase BAMEG_2047 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAMEG_2048 ENOG4107QX3 carboxylase BAMEG_2049 ENOG4105E39 Enoyl-CoA hydratase BAMEG_2050 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAMEG_2051 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAMEG_2052 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAMEG_2053 ENOG4105C1G acyl-Coa dehydrogenase BAMEG_2056 ENOG4107Z3H Transcriptional regulator, TetR family BAMEG_2058 ENOG4105CJ1 ABC, transporter BAMEG_2061 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BAMEG_2062 ENOG4105CEP NADH dehydrogenase BAMEG_2063 ENOG4106ANW SMI1_KNR4 BAMEG_2066 ENOG4105BZU Histidine kinase BAMEG_2068 ENOG4105C5H ABC transporter BAMEG_2069 ENOG41067SE Tetr family transcriptional regulator BAMEG_2070 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BAMEG_2074 ENOG4108VXD carboxy-peptidase BAMEG_2076 ENOG4105VZ8 Transcriptional regulator BAMEG_2079 ENOG4105CGH 5'-nucleotidase BAMEG_2080 ENOG4105CGH 5'-nucleotidase BAMEG_2084 ENOG4105DH8 myo-inositol catabolism BAMEG_2085 ENOG4105D2N Aldolase BAMEG_2091 ENOG4105CK5 oxidoreductase BAMEG_2092 ENOG4105IE8 Alpha-ketoglutarate permease BAMEG_2093 ENOG4105ETE Transcriptional regulator (LacI family BAMEG_2094 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAMEG_2096 ENOG4107RF6 penicillin-binding protein BAMEG_2097 ENOG4107RF6 penicillin-binding protein BAMEG_2099 ENOG4107RF6 penicillin-binding protein BAMEG_2105 ENOG4105CIN aminoacyl-histidine dipeptidase BAMEG_2114 ENOG41090HR transcriptional regulator BAMEG_2115 ENOG4107RA9 decarboxylase BAMEG_2116 ENOG4108I0C methyltransferase BAMEG_2118 ENOG41088CC tellurite resistance protein tehB BAMEG_2123 ENOG4108RZE Tetr family transcriptional regulator BAMEG_2127 ENOG4105C1J atp-dependent rna helicase BAMEG_2130 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAMEG_2133 ENOG4107STF Involved in phosphonate degradation (By similarity) BAMEG_2135 ENOG4105RD7 BadF BadG BcrA BcrD BAMEG_2141 ENOG4105F32 YngK protein BAMEG_2147 ENOG4108KPJ rna polymerase sigma factor BAMEG_2153 ENOG4108JCI Transcriptional regulator BAMEG_2156 ENOG4105BZ1 (ABC) transporter BAMEG_2157 ENOG4105BZ1 (ABC) transporter BAMEG_2160 ENOG4108RPX mosc domain containing protein BAMEG_2161 ENOG4105DND Transcriptional regulator BAMEG_2164 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAMEG_2165 ENOG4107V2S Transcriptional regulator BAMEG_2172 ENOG410667J hydrolase BAMEG_2176 ENOG4105VEQ Cold shock protein BAMEG_2178 ENOG41068WN BAMEG_2180 ENOG4105C1Q protoporphyrinogen oxidase BAMEG_2186 ENOG4105WCN acetyltransferase BAMEG_2191 ENOG4105EYF MMPL domain protein BAMEG_2193 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAMEG_2195 ENOG41081I9 integral membrane protein BAMEG_2201 ENOG4108D32 Methyltransferase BAMEG_2207 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAMEG_2211 ENOG4105C19 ABC transporter BAMEG_2212 ENOG4105C22 threonyL-tRNA synthetase BAMEG_2214 ENOG4105FE9 pseudouridine synthase BAMEG_2219 ENOG4105BZG amino acid carrier protein BAMEG_2223 ENOG4105K70 DNA-binding protein BAMEG_2226 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_2227 ENOG4105WQT MbtH domain protein BAMEG_2228 ENOG4105CEY Amp-dependent synthetase and ligase BAMEG_2229 ENOG4105WQI isochorismatase BAMEG_2230 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAMEG_2231 ENOG4105E4F Isochorismate synthase BAMEG_2232 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAMEG_2233 ENOG4105FCD Major Facilitator BAMEG_2240 ENOG4105EYH Exonuclease BAMEG_2241 ENOG4107RFY SbcCD D subunit BAMEG_2244 ENOG4105E39 Enoyl-CoA hydratase BAMEG_2245 ENOG4105N14 lysine exporter protein LysE YggA BAMEG_2247 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAMEG_2248 ENOG4105C1G acyl-Coa dehydrogenase BAMEG_2250 ENOG4105CR4 methylisocitrate lyase BAMEG_2251 ENOG4105DXD 2-methylcitrate dehydratase BAMEG_2253 ENOG4105W8X HesB YadR YfhF-family protein BAMEG_2254 ENOG4105CZM Major Facilitator BAMEG_2255 ENOG4105BZ4 penicillin-binding protein BAMEG_2262 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAMEG_2280 ENOG4108IBT Inherit from COG: transposase BAMEG_2283 ENOG4105SZ6 Thioredoxin BAMEG_2284 ENOG410841Q phosphoesterase PA-phosphatase related protein BAMEG_2286 ENOG4108N23 SpoOM-related protein BAMEG_2294 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAMEG_2295 ENOG4108JUB Transcriptional regulator BAMEG_2296 ENOG4108TSC N-acetyltransferase BAMEG_2297 ENOG4107S4Y M20 DapE family protein YgeY BAMEG_2300 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAMEG_2306 ENOG4105C37 (CBS) domain BAMEG_2313 ENOG4105E90 ABC transporter BAMEG_2314 ENOG4108IJ8 ABC transporter BAMEG_2320 ENOG4105CMG Carbohydrate kinase BAMEG_2321 ENOG4105CMG Carbohydrate kinase BAMEG_2329 ENOG4106KNT transcriptional regulator BAMEG_2331 ENOG4105WH1 Two component transcriptional regulator luxr family BAMEG_2332 ENOG4105BZU Histidine kinase BAMEG_2333 ENOG4105D8X mechanosensitive ion channel BAMEG_2340 ENOG4105F0I Aminotransferase BAMEG_2341 ENOG4108MES Periplasmic binding protein BAMEG_2345 ENOG4105CAQ asparagine synthetase BAMEG_2346 ENOG4107Y70 Heat shock protein BAMEG_2347 ENOG4108KF3 Electron transport protein SCO1 SenC BAMEG_2348 ENOG4105E8R UPF0173 metal-dependent hydrolase BAMEG_2349 ENOG4108RCR degv family BAMEG_2351 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAMEG_2353 ENOG4108UT2 hemolysin iii BAMEG_2354 ENOG4105E9Q Acyl-transferase BAMEG_2355 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAMEG_2356 ENOG4107RVG penicillin-binding protein BAMEG_2359 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BAMEG_2363 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BAMEG_2369 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BAMEG_2371 ENOG4105KD7 acetyltransferase BAMEG_2374 ENOG4105C0A alcohol dehydrogenase BAMEG_2375 ENOG4105CY2 Citrate transporter BAMEG_2376 ENOG4107XGZ Hydrolase BAMEG_2380 ENOG4105C8J )-transporter BAMEG_2383 ENOG41062D9 Histidine kinase BAMEG_2384 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_2385 ENOG4107QPK )-transporter BAMEG_2386 ENOG4105BZW Glycerate kinase BAMEG_2406 ENOG4105EC2 ftsk spoIIIe BAMEG_2410 ENOG4105C5S asparaginyl-tRNA synthetase BAMEG_2411 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAMEG_2414 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAMEG_2420 ENOG4105C75 arginyL-tRNA synthetase BAMEG_2421 ENOG4107YX5 Pfam:DUF548 BAMEG_2425 ENOG41061H0 Monooxygenase BAMEG_2428 ENOG4108UUM single-stranded DNA-binding protein BAMEG_2431 ENOG4105C5H ABC transporter BAMEG_2436 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAMEG_2438 ENOG4105MCT stage V sporulation protein S BAMEG_2445 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BAMEG_2446 ENOG4108IFG nitrite reductase, (NAD(P)H) BAMEG_2447 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAMEG_2448 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAMEG_2449 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAMEG_2450 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAMEG_2455 ENOG4108ZAF Molybdopterin BAMEG_2456 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAMEG_2457 ENOG4105D06 uba thif-type nad fad binding protein BAMEG_2458 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAMEG_2459 ENOG4107V6Q Cyclic nucleotide-binding domain BAMEG_2464 ENOG4105R3A Nitrate reductase BAMEG_2465 ENOG4108IUE nitrate reductase beta subunit BAMEG_2469 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAMEG_2472 ENOG4108V06 Glutathione peroxidase BAMEG_2477 ENOG4105EMN RNA polymerase sigma factor BAMEG_2478 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BAMEG_2480 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_2481 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAMEG_2485 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAMEG_2490 ENOG4105KBJ sporulation protein ytfj BAMEG_2499 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAMEG_2506 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAMEG_2507 ENOG4108JYZ YitT family BAMEG_2508 ENOG41087PP glycosyltransferase MGT family BAMEG_2511 ENOG4107RBS Methyltransferase BAMEG_2512 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAMEG_2514 ENOG4108X4Q Hydrolase BAMEG_2519 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAMEG_2521 ENOG4108VXD carboxy-peptidase BAMEG_2523 ENOG4108ZRV stage ii sporulation protein p BAMEG_2526 ENOG4108Z7R Chaperone CsaA BAMEG_2530 ENOG4105C37 (CBS) domain BAMEG_2531 ENOG4105SXS Protein of unknown function (DUF456) BAMEG_2536 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAMEG_2537 ENOG4108S4H thioesterase Superfamily protein BAMEG_2539 ENOG4108PJD permease BAMEG_2542 ENOG4107T5V SNARE associated Golgi BAMEG_2546 ENOG4105CVJ phosphoglycerate mutase BAMEG_2551 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAMEG_2553 ENOG4105K4T epimerase BAMEG_2555 ENOG4105DSE periplasmic solute binding protein BAMEG_2565 ENOG4105CKI cobalamin synthesis protein BAMEG_2566 ENOG4107QM2 Aldo Keto reductase BAMEG_2570 ENOG4105DEN Luciferase family BAMEG_2573 ENOG4108WPJ Ferritin-like domain BAMEG_2574 ENOG4108K88 Membrane BAMEG_2577 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_2582 ENOG4107XZQ multidrug resistance protein BAMEG_2583 ENOG4107SET aldo keto reductase BAMEG_2584 ENOG4105YVS arsR family transcriptional regulator BAMEG_2586 ENOG4105KRN Transcriptional regulator, abrb family BAMEG_2599 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAMEG_2601 ENOG4107RCC Major Facilitator Superfamily BAMEG_2603 ENOG4105YWU small acid-soluble spore protein BAMEG_2604 ENOG4108WBH protein TIM barrel BAMEG_2607 ENOG4105CEY Amp-dependent synthetase and ligase BAMEG_2609 ENOG4105DUU IucA IucC family protein BAMEG_2611 ENOG4105VRR gCN5-related N-acetyltransferase BAMEG_2612 ENOG4105KT7 mgtC SapB transporter BAMEG_2614 ENOG4107VMI polysaccharide deacetylase BAMEG_2615 ENOG4105BZU Histidine kinase BAMEG_2616 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_2618 ENOG4108KGH TRANSCRIPTIONal BAMEG_2623 ENOG4105D6E homoserine dehydrogenase BAMEG_2629 ENOG4108ZJ4 polysaccharide deacetylase BAMEG_2630 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAMEG_2634 ENOG4105BZU Histidine kinase BAMEG_2635 ENOG4105EFI regulatoR BAMEG_2636 ENOG4105BZ1 (ABC) transporter BAMEG_2637 ENOG4105BZ1 (ABC) transporter BAMEG_2645 ENOG4108JJ8 (ABC) transporter BAMEG_2646 ENOG4108JJ9 ABC, transporter BAMEG_2647 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAMEG_2648 ENOG4105C4M (Ubiquinol oxidase) subunit I BAMEG_2650 ENOG4105YGB Transcriptional regulator BAMEG_2654 ENOG4105SKE transcriptional Regulator LysR family BAMEG_2656 ENOG4105C32 Amino acid ABC transporter (Permease) BAMEG_2657 ENOG4108IV0 ABC, transporter BAMEG_2658 ENOG4105C0Z ABC transporter BAMEG_2660 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAMEG_2661 ENOG4108Z7G MaoC domain protein dehydratase BAMEG_2665 ENOG4105CKI cobalamin synthesis protein BAMEG_2667 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAMEG_2668 ENOG4106F5Q Membrane BAMEG_2669 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAMEG_2671 ENOG4108TVJ Nitroreductase BAMEG_2672 ENOG4107ZXU DSBA oxidoreductase BAMEG_2673 ENOG4108Z40 Transcriptional regulator BAMEG_2674 ENOG4105GZI Transcriptional regulator BAMEG_2675 ENOG4107RT3 EamA-like transporter family BAMEG_2677 ENOG4105KTB nuclear export factor GLE1 BAMEG_2678 ENOG4108T5E Copper resistance protein BAMEG_2689 ENOG4107R16 Multicopper oxidase BAMEG_2690 ENOG4107STQ Multicopper oxidase BAMEG_2691 ENOG4107RAQ aminopeptidase BAMEG_2698 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAMEG_2699 ENOG4105D9N nucleoside BAMEG_2701 ENOG4107RHR regulatoR BAMEG_2706 ENOG4105C0X amino acid BAMEG_2707 ENOG4105C0X amino acid BAMEG_2710 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAMEG_2712 ENOG4105C72 UPF0176 protein BAMEG_2713 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAMEG_2718 ENOG41068WN BAMEG_2724 ENOG4108J59 Extracellular solute-binding protein, family 5 BAMEG_2725 ENOG4105F6J Alpha beta hydrolase fold BAMEG_2730 ENOG4105CYC Transferase BAMEG_2731 ENOG4105DY9 regulatoR BAMEG_2733 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BAMEG_2734 ENOG4105C6X Major Facilitator BAMEG_2738 ENOG4105C7B Threonine dehydratase BAMEG_2740 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAMEG_2741 ENOG4108ZP8 Acetolactate synthase small subunit BAMEG_2742 ENOG4105C7K acetolactate synthase BAMEG_2743 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAMEG_2744 ENOG4105CHR reductase BAMEG_2745 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAMEG_2748 ENOG4106KE4 Dehydrogenase BAMEG_2752 ENOG4105H67 Protein of unknown function (DUF421) BAMEG_2753 ENOG4105X5K response regulator receiver protein BAMEG_2755 ENOG4105C8J )-transporter BAMEG_2759 ENOG4105C6T cysteine synthase BAMEG_2760 ENOG4105EU0 Major facilitator Superfamily BAMEG_2763 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAMEG_2766 ENOG4105DXI Major Facilitator superfamily BAMEG_2767 ENOG4105DXI Major Facilitator superfamily BAMEG_2768 ENOG4105CSR polyphosphate kinase 2 BAMEG_2776 ENOG4105FVX BAMEG_2791 ENOG4105C6K Malic enzyme BAMEG_2792 ENOG4108IJ0 Aspartate ammonia-lyase BAMEG_2794 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAMEG_2798 ENOG4105CJ1 ABC, transporter BAMEG_2805 ENOG4106BRA Membrane BAMEG_2812 ENOG4107QIV Cytochrome c biogenesis protein BAMEG_2816 ENOG4105EC3 peptidase S51, dipeptidase E BAMEG_2817 ENOG4107QJQ Mate efflux family protein BAMEG_2818 ENOG4107QJQ Mate efflux family protein BAMEG_2822 ENOG4105C9Q fumarate hydratase class II BAMEG_2823 ENOG4105DFD Na H antiporter BAMEG_2827 ENOG4108PJD permease BAMEG_2828 ENOG4105CKI cobalamin synthesis protein BAMEG_2829 ENOG4108UZ3 Transporter BAMEG_2830 ENOG4105DRR Transcriptional regulator, GntR family BAMEG_2832 ENOG4105PGM cation diffusion facilitator family transporter BAMEG_2836 ENOG4105CAQ asparagine synthetase BAMEG_2843 ENOG4105CVJ phosphoglycerate mutase BAMEG_2850 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAMEG_2851 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BAMEG_2852 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAMEG_2853 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_2854 ENOG4105DUM transcriptional regulator, lysR family BAMEG_2859 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAMEG_2862 ENOG4108RZE Tetr family transcriptional regulator BAMEG_2867 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAMEG_2868 ENOG4105KTQ flagellar basal-body rod protein BAMEG_2869 ENOG4105FZW flagellar biosynthesis regulator FlhF BAMEG_2870 ENOG4105D7B Flagellar biosynthesis protein flha BAMEG_2871 ENOG4105D00 flagellar biosynthetic protein flhB BAMEG_2873 ENOG4105VS8 Flagellar biosynthetic protein fliq BAMEG_2874 ENOG4105CN7 Flagellar biosynthetic protein FliP BAMEG_2876 ENOG4105DD5 Flagellar motor switch protein BAMEG_2878 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAMEG_2880 ENOG4105E4C Lytic transglycosylase catalytic BAMEG_2881 ENOG4105I03 Flagellin BAMEG_2886 ENOG4107TVC Glycosyl transferase, family 2 BAMEG_2893 ENOG4105K64 Glycosyl transferase, family 2 BAMEG_2895 ENOG4107R88 Chemotaxis protein (CheV) BAMEG_2899 ENOG4105BZE flagellar hook protein, FlgE BAMEG_2907 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAMEG_2909 ENOG4107U2N Flagellar M-ring protein BAMEG_2910 ENOG41075Z6 flagellar hook-basal body complex protein fliE BAMEG_2911 ENOG4108ZC9 flagellar basal-body rod protein flgc BAMEG_2912 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAMEG_2917 ENOG4105DTJ flagellar hook-associated protein BAMEG_2923 ENOG4105BZU Histidine kinase BAMEG_2926 ENOG4105DD5 Flagellar motor switch protein BAMEG_2927 ENOG4105CBS Chea signal transduction histidine kinase BAMEG_2928 ENOG4105CBS Chea signal transduction histidine kinase BAMEG_2929 ENOG4107YTP response regulator receiver protein BAMEG_2930 ENOG4105ER2 Ompa motb domain protein BAMEG_2931 ENOG4107R0U MotA TolQ exbB proton channel BAMEG_2934 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAMEG_2945 ENOG41080C8 DUF218 domain BAMEG_2947 ENOG4105H67 Protein of unknown function (DUF421) BAMEG_2949 ENOG4108Z5V transcriptional regulator, merr family BAMEG_2950 ENOG4105CN5 Metallo-Beta-Lactamase BAMEG_2951 ENOG4105CN5 Metallo-Beta-Lactamase BAMEG_2952 ENOG4107RWR Sodium hydrogen exchanger BAMEG_2954 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAMEG_2968 ENOG41081VK Ribonuclease BAMEG_2972 ENOG4108SZE gCN5-related N-acetyltransferase BAMEG_2975 ENOG4105CPK Glycosyl transferase (Group 1 BAMEG_2989 ENOG4106032 Glutathionylspermidine synthase BAMEG_2994 ENOG4105KHC sulfurtransferase BAMEG_2996 ENOG4108W0I acetyltransferase BAMEG_2998 ENOG410890F Dynamin family BAMEG_3000 ENOG4105DHF Membrane BAMEG_3001 ENOG4105C2W permease BAMEG_3005 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAMEG_3008 ENOG4105CTD carboxy-peptidase BAMEG_3009 ENOG4105DVT helicase BAMEG_3011 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAMEG_3023 ENOG4105BZ4 penicillin-binding protein BAMEG_3025 ENOG4105CSM endonuclease III BAMEG_3029 ENOG4105YAC BAMEG_3030 ENOG4105DVT helicase BAMEG_3037 ENOG4105CPK Glycosyl transferase (Group 1 BAMEG_3038 ENOG4105FJR Lmbe family BAMEG_3041 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAMEG_3042 ENOG4108JYZ YitT family BAMEG_3048 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BAMEG_3049 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAMEG_3050 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BAMEG_3053 ENOG41068YB TPR repeat-containing protein BAMEG_3054 ENOG4105CIH Imidazole acetol-phosphate transaminase BAMEG_3058 ENOG4105EAH synthase BAMEG_3060 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAMEG_3063 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAMEG_3069 ENOG41065D1 BAMEG_3070 ENOG4105S2F BAMEG_3076 ENOG4107RB3 L-asparaginase BAMEG_3077 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAMEG_3082 ENOG4108S6Z Negative regulator of genetic competence BAMEG_3083 ENOG4107X2D transcriptional regulator, merr family BAMEG_3084 ENOG4107RGJ metallophosphoesterase BAMEG_3085 ENOG4107RGJ metallophosphoesterase BAMEG_3087 ENOG4105I7S Abortive infection protein BAMEG_3088 ENOG4105C9U ATP-dependent DNA helicase RecQ BAMEG_3089 ENOG4105T7X BAMEG_3091 ENOG4108SAX Membrane BAMEG_3095 ENOG4108WBT adenosyltransferase BAMEG_3096 ENOG4105BZU Histidine kinase BAMEG_3097 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_3098 ENOG4105CRE cytochrome C BAMEG_3099 ENOG4107TWT Cytochrome c biogenesis protein BAMEG_3101 ENOG4105FE9 pseudouridine synthase BAMEG_3103 ENOG4108JIC nucleoside recognition domain protein BAMEG_3104 ENOG4105DZ1 carboxypeptidase BAMEG_3105 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAMEG_3112 ENOG4105BZU Histidine kinase BAMEG_3115 ENOG4105I3N Conserved Protein BAMEG_3116 ENOG4105BZU Histidine kinase BAMEG_3119 ENOG4105BZ4 penicillin-binding protein BAMEG_3120 ENOG4107GRR phosphate transport regulator BAMEG_3121 ENOG4105CJ3 phosphate transporter BAMEG_3125 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAMEG_3130 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BAMEG_3134 ENOG4105WH1 Two component transcriptional regulator luxr family BAMEG_3135 ENOG4105ENE Histidine kinase BAMEG_3139 ENOG4105DFD Na H antiporter BAMEG_3144 ENOG4105C8J )-transporter BAMEG_3145 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAMEG_3146 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAMEG_3147 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAMEG_3149 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAMEG_3150 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAMEG_3155 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAMEG_3158 ENOG4105E0M Sulfatase BAMEG_3159 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAMEG_3162 ENOG4107RVV histidinol phosphate phosphatase, hisj family BAMEG_3169 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAMEG_3174 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAMEG_3176 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAMEG_3177 ENOG4108ZP8 Acetolactate synthase small subunit BAMEG_3178 ENOG4105C7K acetolactate synthase BAMEG_3179 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAMEG_3184 ENOG4105KBJ sporulation protein ytfj BAMEG_3185 ENOG41063Y9 BAMEG_3186 ENOG4105CZN Potassium uptake protein BAMEG_3192 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAMEG_3193 ENOG4107QMU Mate efflux family protein BAMEG_3200 ENOG4105NQC Flavodoxin BAMEG_3205 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAMEG_3207 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAMEG_3208 ENOG4105EA8 2-Nitropropane dioxygenase BAMEG_3209 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAMEG_3217 ENOG4105CJ1 ABC, transporter BAMEG_3219 ENOG4105CZV ABC transporter BAMEG_3220 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAMEG_3221 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAMEG_3222 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAMEG_3224 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAMEG_3225 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BAMEG_3234 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAMEG_3235 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BAMEG_3238 ENOG4105BZU Histidine kinase BAMEG_3240 ENOG4106DF1 BAMEG_3242 ENOG41090MY MarR family Transcriptional regulator BAMEG_3243 ENOG4105BZU Histidine kinase BAMEG_3245 ENOG4105PXI polysaccharide deacetylase BAMEG_3247 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAMEG_3248 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAMEG_3253 ENOG4105E98 transcriptional regulator DeoR family BAMEG_3256 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BAMEG_3257 ENOG4107RCV ABC transporter, permease BAMEG_3259 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_3260 ENOG4105C4Y ABC transporter BAMEG_3264 ENOG4105MWK D-amino acid dehydrogenase, small subunit BAMEG_3266 ENOG4105CHR reductase BAMEG_3270 ENOG4108Z7G MaoC domain protein dehydratase BAMEG_3271 ENOG410681C small acid-soluble spore protein BAMEG_3272 ENOG4105CZN Potassium uptake protein BAMEG_3275 ENOG4107TS3 membrane protein, TerC BAMEG_3276 ENOG4108QTI )-transporter BAMEG_3279 ENOG4106A3R peptidase BAMEG_3283 ENOG4105JXH GntR family transcriptional regulator BAMEG_3284 ENOG4105BZU Histidine kinase BAMEG_3285 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_3288 ENOG4105CQB FAD linked oxidase domain protein BAMEG_3289 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAMEG_3290 ENOG4105K4I Scp-like extracellular BAMEG_3292 ENOG4108YBP pseudouridine synthase BAMEG_3294 ENOG4105EYF MMPL domain protein BAMEG_3296 ENOG4107RUE extracellular solute-binding protein family 1 BAMEG_3297 ENOG4105D38 putrescine abc transporter BAMEG_3298 ENOG4105F38 ABC transporter, permease BAMEG_3299 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_3300 ENOG4105C26 Dehydrogenase BAMEG_3308 ENOG4105VFR signal peptidase BAMEG_3309 ENOG4105DZ1 carboxypeptidase BAMEG_3311 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BAMEG_3321 ENOG4105VZ8 Transcriptional regulator BAMEG_3323 ENOG4105C7S Dehydrogenase BAMEG_3341 ENOG4105DDQ anthranilate synthase BAMEG_3342 ENOG4105CRQ synthase (Component I) BAMEG_3344 ENOG4105CK7 Sodium proline symporter BAMEG_3349 ENOG4108WVJ 2'-5' rna ligase BAMEG_3359 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAMEG_3361 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BAMEG_3362 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAMEG_3366 ENOG4107TVC Glycosyl transferase, family 2 BAMEG_3370 ENOG4105K64 Glycosyl transferase, family 2 BAMEG_3372 ENOG4105CNI cell division protein FtsW BAMEG_3375 ENOG4105EMS pseudouridine synthase BAMEG_3376 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAMEG_3379 ENOG4105MIX Adenylate cyclase BAMEG_3380 ENOG4108Z18 K06886 hemoglobin BAMEG_3383 ENOG4105DPN Oligoendopeptidase f BAMEG_3385 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAMEG_3387 ENOG4108ZCF integral membrane protein BAMEG_3392 ENOG4105UQX Mate efflux family protein BAMEG_3393 ENOG4108JQ7 (ABC) transporter BAMEG_3395 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAMEG_3396 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAMEG_3399 ENOG4105C31 Tryptophanyl-tRNA synthetase BAMEG_3402 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAMEG_3403 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAMEG_3408 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAMEG_3411 ENOG4108KP7 hydrolase BAMEG_3413 ENOG41073B9 BAMEG_3414 ENOG4107AYK membrAne BAMEG_3416 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAMEG_3418 ENOG4105QNR S1 RNA binding domain protein BAMEG_3422 ENOG4105BZU Histidine kinase BAMEG_3423 ENOG4105CH6 catalase BAMEG_3424 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAMEG_3425 ENOG4105CAQ asparagine synthetase BAMEG_3430 ENOG4105ERH Fumarylacetoacetate hydrolase BAMEG_3439 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAMEG_3440 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAMEG_3443 ENOG4105XVF Competence transcription factor BAMEG_3446 ENOG4105VEQ Cold shock protein BAMEG_3449 ENOG4107QP3 malate synthase g BAMEG_3450 ENOG4105ZU5 s-layer protein BAMEG_3455 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_3456 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAMEG_3461 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_3465 ENOG41086D8 Transcriptional regulator BAMEG_3466 ENOG4108AEY RNA polymerase sigma factor BAMEG_3468 ENOG4107TVP HD domain protein BAMEG_3469 ENOG4107RN3 metallophosphoesterase BAMEG_3471 ENOG4105ENX hydrolase BAMEG_3479 ENOG4105CNA YD repeat protein BAMEG_3485 ENOG4105CEY Amp-dependent synthetase and ligase BAMEG_3487 ENOG4105DF9 Lipoate-protein, ligase BAMEG_3488 ENOG4108RQ5 Beta-lactamase domain-containing protein BAMEG_3489 ENOG4106AXD BAMEG_3495 ENOG4105ECB domain protein BAMEG_3498 ENOG4105NA0 Transcriptional regulator BAMEG_3503 ENOG4105C1Q protoporphyrinogen oxidase BAMEG_3505 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAMEG_3506 ENOG4105BZ4 penicillin-binding protein BAMEG_3507 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAMEG_3508 ENOG4105CKV Membrane BAMEG_3509 ENOG410905X membrane-flanked domain protein BAMEG_3517 ENOG4105CKV Membrane BAMEG_3519 ENOG410905X membrane-flanked domain protein BAMEG_3526 ENOG4105K59 histidine triad (HIT) protein BAMEG_3531 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAMEG_3532 ENOG4105EEM helicase BAMEG_3534 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_3535 ENOG4105C57 major facilitator superfamily BAMEG_3540 ENOG4105EMN RNA polymerase sigma factor BAMEG_3543 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAMEG_3546 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAMEG_3551 ENOG4108MUZ hydrolase BAMEG_3556 ENOG4105EQ0 Major Facilitator superfamily BAMEG_3557 ENOG4108IND Tetr family transcriptional regulator BAMEG_3560 ENOG4105D7V transposase BAMEG_3562 ENOG4106D4I domain protein BAMEG_3563 ENOG4107VRP DNA repair exonuclease BAMEG_3570 ENOG4105K8R UPF0145 protein BAMEG_3575 ENOG4105BZU Histidine kinase BAMEG_3576 ENOG4105BZU Histidine kinase BAMEG_3577 ENOG4108MJI response regulator BAMEG_3579 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_3581 ENOG4105WN5 stage II sporulation protein BAMEG_3594 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BAMEG_3602 ENOG410847I Transcriptional regulator, BadM Rrf2 family BAMEG_3603 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAMEG_3604 ENOG4105CMT Dihydroxyacetone kinase BAMEG_3606 ENOG4105CMT Dihydroxyacetone kinase BAMEG_3610 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAMEG_3614 ENOG4108IG5 Transcriptional regulator BAMEG_3615 ENOG4107P5I polyketide synthase BAMEG_3624 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_3632 ENOG4105CDU Replicative dna helicase BAMEG_3641 ENOG4108MRH transcriptional regulatory protein BAMEG_3643 ENOG4105CSH Transporter BAMEG_3649 ENOG4108JQ7 (ABC) transporter BAMEG_3652 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAMEG_3661 ENOG4105CTU Proline racemase BAMEG_3665 ENOG4105DER m42 family BAMEG_3668 ENOG4105CGU Enoyl-CoA hydratase BAMEG_3671 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAMEG_3672 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAMEG_3674 ENOG4106AKK s-layer domain-containing protein BAMEG_3682 ENOG4105CHH sulfate transporter BAMEG_3685 ENOG4105D4P Coproporphyrinogen iii oxidase BAMEG_3687 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAMEG_3692 ENOG4107FQX Alpha-acetolactate decarboxylase BAMEG_3699 ENOG410839P BAMEG_3702 ENOG4105CDA abc transporter atp-binding protein BAMEG_3703 ENOG4105DRP amino acid AbC transporter BAMEG_3705 ENOG4105BZ1 (ABC) transporter BAMEG_3706 ENOG4105BZ1 (ABC) transporter BAMEG_3707 ENOG4105BZ1 (ABC) transporter BAMEG_3708 ENOG4105C26 Dehydrogenase BAMEG_3710 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAMEG_3712 ENOG4105D5Q Arginine ornithine antiporter BAMEG_3714 ENOG4105CH6 catalase BAMEG_3715 ENOG4107RKG DJ-1/PfpI family BAMEG_3717 ENOG4105E5W Transporter BAMEG_3718 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAMEG_3719 ENOG4105NF4 modulator of drug activity BAMEG_3724 ENOG4105KPY Small multidrug resistance protein BAMEG_3725 ENOG4105KPY Small multidrug resistance protein BAMEG_3727 ENOG4108YXU transcriptional regulator AsnC family BAMEG_3728 ENOG4108PCN EamA-like transporter family BAMEG_3735 ENOG4106KNT transcriptional regulator BAMEG_3737 ENOG4107RWR Sodium hydrogen exchanger BAMEG_3738 ENOG4105CUB amino acid BAMEG_3745 ENOG4107T5V SNARE associated Golgi BAMEG_3753 ENOG4105WEF catalase BAMEG_3760 ENOG4105C19 ABC transporter BAMEG_3761 ENOG4107RBB ABC transporter, permease BAMEG_3762 ENOG41069ER domain protein BAMEG_3766 ENOG4105VZJ PTS System BAMEG_3767 ENOG4105VCP PTS System BAMEG_3768 ENOG4105EMD TRANSCRIPTIONal BAMEG_3774 ENOG4108KGH TRANSCRIPTIONal BAMEG_3776 ENOG41087NI Sulfite exporter TauE/SafE BAMEG_3777 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BAMEG_3779 ENOG41085GJ domain protein BAMEG_3780 ENOG4105VFE sira family BAMEG_3781 ENOG4107TPS domain protein BAMEG_3782 ENOG4105VFE sira family BAMEG_3783 ENOG4105XTG Pfam:DUF156 BAMEG_3784 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BAMEG_3790 ENOG4105ED1 spovr family BAMEG_3791 ENOG4107Y03 Nitroreductase BAMEG_3796 ENOG4108B31 Spore germination protein BAMEG_3797 ENOG4108B31 Spore germination protein BAMEG_3804 ENOG4105C5Y PTS System BAMEG_3811 ENOG4105C7N Xanthine uracil vitamin C permease BAMEG_3814 ENOG4108INS Transcriptional regulator BAMEG_3825 ENOG4105DWF phosphomethylpyrimidine kinase BAMEG_3826 ENOG4105D06 uba thif-type nad fad binding protein BAMEG_3829 ENOG41080HI glycine oxidase BAMEG_3830 ENOG4108VEU Thiamine monophosphate synthase BAMEG_3832 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAMEG_3834 ENOG4105ETU transcriptional activator (TenA BAMEG_3841 ENOG41080XQ Signal transduction protein with cbs domains BAMEG_3868 ENOG4105E2Z phosphate ABC transporter (Permease BAMEG_3869 ENOG4105C8U phosphate abc transporter BAMEG_3871 ENOG4105CVA phosphate BAMEG_3872 ENOG4105CE1 Ferrous iron transport protein b BAMEG_3873 ENOG4105CE1 Ferrous iron transport protein b BAMEG_3876 ENOG4108NHD germination protein BAMEG_3879 ENOG4105E1V na solute symporter BAMEG_3880 ENOG4106CAD Protein of unknown function (DUF3311) BAMEG_3883 ENOG4105E2S oxidase) subunit II BAMEG_3884 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAMEG_3892 ENOG4105C7N Xanthine uracil vitamin C permease BAMEG_3893 ENOG4105C85 amino acid BAMEG_3897 ENOG4105DUX Transporter BAMEG_3899 ENOG4107D63 BAMEG_3900 ENOG4105VZ8 Transcriptional regulator BAMEG_3901 ENOG41069ER domain protein BAMEG_3902 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAMEG_3903 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAMEG_3916 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAMEG_3917 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAMEG_3918 ENOG4105CNN ABC, transporter BAMEG_3919 ENOG4105C2J ABC transporter BAMEG_3921 ENOG4108RVA ribokinase BAMEG_3922 ENOG4105ETE Transcriptional regulator (LacI family BAMEG_3923 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_3924 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_3925 ENOG41067TZ transcriptional regulator, MarR family BAMEG_3926 ENOG4105CXY transporter BAMEG_3928 ENOG4108JQ7 (ABC) transporter BAMEG_3929 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAMEG_3931 ENOG4105DEF Extracellular solute-binding protein, family 5 BAMEG_3933 ENOG41068KF Universal stress protein BAMEG_3934 ENOG4105CHH sulfate transporter BAMEG_3937 ENOG4105BZU Histidine kinase BAMEG_3938 ENOG4105NAE bifunctional deaminase-reductase domain protein BAMEG_3939 ENOG4105D29 Helix-turn-helix type 11 domain protein BAMEG_3944 ENOG4108IQI permease BAMEG_3945 ENOG4105DRP amino acid AbC transporter BAMEG_3946 ENOG4105EAD ABC transporter BAMEG_3947 ENOG4105CT1 (ABC) transporter BAMEG_3948 ENOG4105CDA abc transporter atp-binding protein BAMEG_3949 ENOG4105BZG amino acid carrier protein BAMEG_3950 ENOG4105CRN Aminoglycoside phosphotransferase BAMEG_3952 ENOG4105E1K spore germination protein BAMEG_3955 ENOG4105CG3 alpha amylase, catalytic region BAMEG_3956 ENOG4105C5Y PTS System BAMEG_3957 ENOG4107414 GntR family transcriptional regulator BAMEG_3958 ENOG4105D5Q Arginine ornithine antiporter BAMEG_3959 ENOG4105BZU Histidine kinase BAMEG_3962 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAMEG_3963 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAMEG_3964 ENOG4107T89 von Willebrand factor, type A BAMEG_3966 ENOG4105EXW epimerase dehydratase BAMEG_3968 ENOG4105DMQ Methyltransferase BAMEG_3969 ENOG4105E0A ABC, transporter BAMEG_3970 ENOG4108IHU transport system permease protein BAMEG_3971 ENOG4105DQ5 transport system permease protein BAMEG_3972 ENOG4108MES Periplasmic binding protein BAMEG_3973 ENOG4105DUX Transporter BAMEG_3976 ENOG4105DAA L-lactate BAMEG_3977 ENOG4108IJ0 Aspartate ammonia-lyase BAMEG_3978 ENOG4105C37 (CBS) domain BAMEG_3979 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAMEG_3980 ENOG4105D9N nucleoside BAMEG_3981 ENOG4108KGH TRANSCRIPTIONal BAMEG_3982 ENOG41073R8 VanW family BAMEG_3989 ENOG4105DAP Nicotinate phosphoribosyltransferase BAMEG_3990 ENOG4105C59 p-type ATPase BAMEG_3992 ENOG4105CUB amino acid BAMEG_3997 ENOG4108JB9 formate dehydrogenase BAMEG_3998 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAMEG_3999 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAMEG_4001 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_4002 ENOG4105BZU Histidine kinase BAMEG_4004 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAMEG_4005 ENOG4108UZ3 Transporter BAMEG_4007 ENOG4105C6K Malic enzyme BAMEG_4009 ENOG4108MRH transcriptional regulatory protein BAMEG_4014 ENOG4105US7 Histidine kinase BAMEG_4015 ENOG4108STX response regulator BAMEG_4016 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BAMEG_4017 ENOG4105BZ7 extracellular solute-binding protein family 1 BAMEG_4018 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BAMEG_4019 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAMEG_4020 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_4021 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAMEG_4025 ENOG4105D4T Citrate transporter BAMEG_4026 ENOG4108MRH transcriptional regulatory protein BAMEG_4027 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAMEG_4029 ENOG4105DZ6 Band 7 protein BAMEG_4032 ENOG4105C94 Transporter BAMEG_4036 ENOG4105CYN Serine protein kinase BAMEG_4037 ENOG4105BZU Histidine kinase BAMEG_4038 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAMEG_4040 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAMEG_4042 ENOG4107ZQN disulfide bond BAMEG_4043 ENOG4108JQC penicillin-binding protein 1A BAMEG_4068 ENOG4105G5W regulator Fur family BAMEG_4069 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAMEG_4073 ENOG4108IUW ABC transporter BAMEG_4075 ENOG4105CBC glutamate synthase BAMEG_4076 ENOG4107NBY Membrane BAMEG_4077 ENOG4105BZ1 (ABC) transporter BAMEG_4083 ENOG4106BXE BAMEG_4084 ENOG4105CEN a g-specific adenine glycosylase BAMEG_4085 ENOG41067AE Membrane-bound metal-dependent hydrolase BAMEG_4091 ENOG4105ECP epimerase BAMEG_4092 ENOG4105CI2 imidazolone-5-propionate hydrolase BAMEG_4096 ENOG4105F1A Pyruvate formate-lyase BAMEG_4099 ENOG4105C3I Nad-dependent epimerase dehydratase BAMEG_4100 ENOG4107QQG Dehydrogenase BAMEG_4102 ENOG4105CKK Glycosyl transferase, family 2 BAMEG_4105 ENOG4108A04 Beta-lactamase BAMEG_4106 ENOG4108A04 Beta-lactamase BAMEG_4109 ENOG4105CSV Glutaminase BAMEG_4115 ENOG4108IQI permease BAMEG_4117 ENOG4108JUB Transcriptional regulator BAMEG_4119 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAMEG_4168 ENOG4108IMY Transcriptional regulator BAMEG_4175 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAMEG_4177 ENOG41063PX domain protein BAMEG_4178 ENOG4105D78 K07001 NTE family protein BAMEG_4180 ENOG4105H20 Sporulation integral membrane protein YlbJ BAMEG_4181 ENOG4106H78 methyltransferase BAMEG_4187 ENOG4107TB6 phosphoglycerate mutase BAMEG_4190 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAMEG_4200 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAMEG_4201 ENOG4105CNI cell division protein FtsW BAMEG_4204 ENOG4108IAB Phoh family BAMEG_4208 ENOG4105QA2 BAMEG_4209 ENOG4105CI3 gtp-binding protein typa BAMEG_4211 ENOG4105ECY inositol monophosphatase BAMEG_4215 ENOG4105CXN decarboxylase BAMEG_4223 ENOG4105C7S Dehydrogenase BAMEG_4224 ENOG4105CPP Dehydrogenase, E1 component BAMEG_4227 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAMEG_4228 ENOG4108X4Q Hydrolase BAMEG_4230 ENOG4105CN5 Metallo-Beta-Lactamase BAMEG_4231 ENOG4107ZYR domain protein BAMEG_4238 ENOG4108XRC Protein of unknown function (DUF458) BAMEG_4240 ENOG4107IN1 Protein of unknown function (DUF1797) BAMEG_4244 ENOG4105EPM Diguanylate phosphodiesterase BAMEG_4245 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAMEG_4248 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BAMEG_4250 ENOG4105UIN BAMEG_4263 ENOG4108HGU Histidine kinase BAMEG_4265 ENOG4105CHM Aminotransferase BAMEG_4266 ENOG4105FKQ transcriptional regulator BAMEG_4268 ENOG4105EG2 ABC transporter, permease BAMEG_4270 ENOG4107FKK extracellular solute-binding protein family 1 BAMEG_4272 ENOG4105CG3 alpha amylase, catalytic region BAMEG_4280 ENOG4105CHU acetyl-coa acetyltransferase BAMEG_4287 ENOG4105K7K Transcriptional regulator BAMEG_4288 ENOG4105DTD Dehydrogenase BAMEG_4290 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAMEG_4293 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAMEG_4299 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAMEG_4302 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAMEG_4303 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAMEG_4304 ENOG4106TD9 Diguanylate cyclase BAMEG_4308 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAMEG_4311 ENOG4105CID antiterminator BAMEG_4313 ENOG4105FDP GntR family transcriptional regulator BAMEG_4315 ENOG4105CE4 GlcNAc 6-P deacetylase BAMEG_4322 ENOG4107ZE5 PPIases accelerate the folding of proteins BAMEG_4323 ENOG4105PTM secreted protein BAMEG_4324 ENOG4105J7I hydrolase BAMEG_4326 ENOG4105G6R Stage v sporulation protein ae BAMEG_4328 ENOG4105CZ3 stage V sporulation protein ad BAMEG_4329 ENOG41090VF Stage v sporulation protein ac BAMEG_4333 ENOG4105C8J )-transporter BAMEG_4334 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_4336 ENOG41082AN stage II sporulation protein BAMEG_4337 ENOG4105DZ1 carboxypeptidase BAMEG_4338 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAMEG_4339 ENOG4105DVE abc transporter atp-binding protein BAMEG_4345 ENOG4105D7N magnesium and cobalt transport protein CorA BAMEG_4350 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAMEG_4352 ENOG4105I3K Ferric uptake regulator, Fur family BAMEG_4353 ENOG4105MZ9 stage II sporulation protein m BAMEG_4357 ENOG4105CPC Aldo Keto reductase BAMEG_4359 ENOG4105RHY Pfam:UPF0157 BAMEG_4363 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAMEG_4365 ENOG4105ETE Transcriptional regulator (LacI family BAMEG_4366 ENOG4108YM7 Gcn5-related n-acetyltransferase BAMEG_4371 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAMEG_4372 ENOG4108R6K riboflavin synthase, subunit alpha BAMEG_4376 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAMEG_4377 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAMEG_4378 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAMEG_4379 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAMEG_4381 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAMEG_4384 ENOG4105DFD Na H antiporter BAMEG_4385 ENOG4105CGH 5'-nucleotidase BAMEG_4393 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BAMEG_4396 ENOG4108IXY short-chain dehydrogenase reductase BAMEG_4397 ENOG41069FQ Metallo-beta-lactamase superfamily BAMEG_4399 ENOG4105II7 pyrroline-5-carboxylate reductase BAMEG_4400 ENOG4105EJQ L-serine dehydratase BAMEG_4405 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAMEG_4406 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAMEG_4407 ENOG4105D9U N-acetyltransferase BAMEG_4409 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAMEG_4410 ENOG4108QEG Membrane BAMEG_4411 ENOG4105CDA abc transporter atp-binding protein BAMEG_4412 ENOG4105E5Q amino acid AbC transporter BAMEG_4413 ENOG4108HW3 (ABC) transporter BAMEG_4416 ENOG4105G7B Protein of unknown function (DUF2992) BAMEG_4417 ENOG4105E09 nadh pyrophosphatase BAMEG_4419 ENOG4105C7S Dehydrogenase BAMEG_4420 ENOG4105CPP Dehydrogenase, E1 component BAMEG_4424 ENOG4107RDP Dehydrogenase BAMEG_4426 ENOG4108JUB Transcriptional regulator BAMEG_4428 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAMEG_4431 ENOG4107QQR Sporulation BAMEG_4432 ENOG4105S1Z Stage IV sporulation protein B BAMEG_4433 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAMEG_4435 ENOG4105DX0 Hemolysin A BAMEG_4437 ENOG4105CTB Polyprenyl synthetase BAMEG_4442 ENOG4108ZSR alkaline shock protein BAMEG_4443 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAMEG_4447 ENOG410644B Stage III sporulation protein af BAMEG_4449 ENOG4105KQ4 Stage iii sporulation protein ad BAMEG_4450 ENOG4108CQH stage III sporulation protein AC BAMEG_4451 ENOG4105KR5 Stage iii sporulation protein BAMEG_4452 ENOG4105CD2 stage iii sporulation protein aa BAMEG_4456 ENOG4105DC7 peptidase M24 BAMEG_4459 ENOG4105CBJ Metal-dependent enzyme BAMEG_4460 ENOG4107YBY Hydrolase BAMEG_4466 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAMEG_4467 ENOG4105WZW rhodanese family BAMEG_4471 ENOG41080TC multidrug resistance protein BAMEG_4478 ENOG4105CJ1 ABC, transporter BAMEG_4479 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAMEG_4485 ENOG4105C0D helicase BAMEG_4511 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAMEG_4512 ENOG4105C3R Methionine synthase BAMEG_4516 ENOG4105C28 cystathionine BAMEG_4517 ENOG4105C28 cystathionine BAMEG_4521 ENOG4105C5X domain protein BAMEG_4523 ENOG4105DKQ ROK family BAMEG_4525 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAMEG_4529 ENOG4108UTW Plays a role in the regulation of phosphate uptake BAMEG_4530 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAMEG_4531 ENOG4105E2Z phosphate ABC transporter (Permease BAMEG_4532 ENOG4105C8U phosphate abc transporter BAMEG_4533 ENOG4105PWN phosphate abc transporter BAMEG_4534 ENOG4107RF6 penicillin-binding protein BAMEG_4536 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAMEG_4541 ENOG4105N80 Ferric uptake regulator, Fur family BAMEG_4543 ENOG4105FDK ABC transporter BAMEG_4544 ENOG4108JYZ YitT family BAMEG_4545 ENOG41069ZM Protein of unknown function (DUF2624) BAMEG_4551 ENOG4105EGD dinuclear metal center protein, YbgI family BAMEG_4554 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_4555 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAMEG_4562 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAMEG_4563 ENOG4105KG3 cytidine deaminase BAMEG_4564 ENOG4107YR5 Diacylglycerol kinase BAMEG_4566 ENOG4105CTJ Metal Dependent Phosphohydrolase BAMEG_4567 ENOG4105C9A Phoh family BAMEG_4569 ENOG41068P3 sporulation protein YqfC BAMEG_4570 ENOG4105KTH gatB Yqey BAMEG_4572 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAMEG_4573 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAMEG_4577 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAMEG_4579 ENOG4105CSA Coproporphyrinogen iii oxidase BAMEG_4580 ENOG4105KVH Transcriptional regulator BAMEG_4585 ENOG4105TQK DNA polymerase iii, delta' subunit BAMEG_4587 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAMEG_4589 ENOG4108UK2 deaminase BAMEG_4590 ENOG4105KQC Competence protein BAMEG_4592 ENOG4105DXX methyltransferase BAMEG_4594 ENOG4108WF2 Metal Dependent Phosphohydrolase BAMEG_4596 ENOG410812S Rna-binding protein BAMEG_4598 ENOG4105CQW ribosome biogenesis GTPase YqeH BAMEG_4599 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAMEG_4602 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_4607 ENOG4108TVJ Nitroreductase BAMEG_4611 ENOG4105G6Z alkaline phosphatase BAMEG_4614 ENOG4108MUZ hydrolase BAMEG_4621 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAMEG_4622 ENOG4105MIR Phenylalanine 4-monooxygenase BAMEG_4624 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_4625 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_4633 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAMEG_4634 ENOG4108V5C ABC transporter BAMEG_4636 ENOG4108EKI Dehydrogenase BAMEG_4637 ENOG4105C28 cystathionine BAMEG_4643 ENOG4107XRG penicillin-binding protein BAMEG_4646 ENOG4105CFP Peptidase U32 BAMEG_4647 ENOG4105XYU peptidase (U32 family) BAMEG_4648 ENOG4108VQJ O-methyltransferase BAMEG_4649 ENOG4105HHA aminodeoxychorismate lyase BAMEG_4653 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAMEG_4655 ENOG4105C02 permease BAMEG_4658 ENOG41060CR BAMEG_4659 ENOG4105C7H Helicase, RecD TraA family BAMEG_4661 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAMEG_4662 ENOG4105C3J Cysteine desulfurase BAMEG_4664 ENOG4105D1H recombination factor protein RarA BAMEG_4665 ENOG4108VCI transcription factor, rsfa family BAMEG_4666 ENOG4105CUZ uba thif-type nad fad binding protein BAMEG_4668 ENOG4105CUT histidyl-tRNA synthetase BAMEG_4671 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAMEG_4673 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAMEG_4674 ENOG41076HS cation diffusion facilitator family transporter BAMEG_4675 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAMEG_4677 ENOG4105CKP Polysaccharide Biosynthesis Protein BAMEG_4678 ENOG4108QG2 Membrane BAMEG_4680 ENOG4105VIE preprotein translocase, subunit YajC BAMEG_4683 ENOG41061AI Protein of unknown function (DUF2905) BAMEG_4686 ENOG4108HUF Transporter BAMEG_4688 ENOG4108IPJ Membrane BAMEG_4689 ENOG4108IPJ Membrane BAMEG_4690 ENOG41082BM Transcriptional regulator, arsr family BAMEG_4695 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAMEG_4696 ENOG4108IYU L-aspartate oxidase BAMEG_4699 ENOG4108RPX mosc domain containing protein BAMEG_4700 ENOG4105CQC Prephenate dehydratase BAMEG_4704 ENOG4105EWM Histidine kinase BAMEG_4707 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAMEG_4710 ENOG4105X36 (ribosomal) protein BAMEG_4713 ENOG4105C03 ribonuclease BAMEG_4716 ENOG4107QMS site-determining protein BAMEG_4719 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAMEG_4720 ENOG4105DFF Rod shape-determining protein mreb BAMEG_4724 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAMEG_4725 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAMEG_4727 ENOG41068KH stage VI sporulation protein D BAMEG_4729 ENOG4105D52 delta-aminolevulinic acid dehydratase BAMEG_4734 ENOG4105K56 Transcriptional regulator BAMEG_4739 ENOG4108IUQ atp-dependent protease BAMEG_4744 ENOG4108QCI YvbH-like oligomerisation region BAMEG_4749 ENOG4105M59 Phosphodiesterase, mj0936 family BAMEG_4750 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BAMEG_4752 ENOG4108XJQ germination protein BAMEG_4754 ENOG4108PCX Major Facilitator BAMEG_4757 ENOG4105KBX Transcriptional regulator, TetR family BAMEG_4760 ENOG4105PFC Transcriptional regulator BAMEG_4763 ENOG4105DZC cytosine deaminase BAMEG_4764 ENOG4105DZC cytosine deaminase BAMEG_4765 ENOG4105DEF Extracellular solute-binding protein, family 5 BAMEG_4766 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAMEG_4769 ENOG4108JQ7 (ABC) transporter BAMEG_4770 ENOG4108HRK Histidine kinase BAMEG_4771 ENOG4105DY9 regulatoR BAMEG_4774 ENOG41067S9 phage shock protein C, PspC BAMEG_4775 ENOG4108JCI Transcriptional regulator BAMEG_4777 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BAMEG_4778 ENOG4108Z40 Transcriptional regulator BAMEG_4779 ENOG4105RHA ABC transporter, permease BAMEG_4780 ENOG4108IUX (ABC) transporter BAMEG_4781 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BAMEG_4782 ENOG4105ER2 Ompa motb domain protein BAMEG_4783 ENOG4105ER2 Ompa motb domain protein BAMEG_4784 ENOG4105E14 MotA TolQ exbB proton channel BAMEG_4785 ENOG4108VXD carboxy-peptidase BAMEG_4787 ENOG4105E33 succinate dehydrogenase BAMEG_4789 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAMEG_4792 ENOG4105K63 Thioredoxin BAMEG_4793 ENOG4105C10 Electron transfer flavoprotein BAMEG_4794 ENOG4105BZJ Electron transfer flavoprotein BAMEG_4795 ENOG41060WC Enoyl-CoA hydratase BAMEG_4796 ENOG4107Z3H Transcriptional regulator, TetR family BAMEG_4797 ENOG4105CEY Amp-dependent synthetase and ligase BAMEG_4800 ENOG4105J76 Periplasmic binding protein BAMEG_4801 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAMEG_4809 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_4812 ENOG4105DR4 Methyltransferase BAMEG_4815 ENOG4105KFN sortase, SrtB family BAMEG_4816 ENOG4105E0A ABC, transporter BAMEG_4819 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BAMEG_4821 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BAMEG_4823 ENOG4105FE9 pseudouridine synthase BAMEG_4825 ENOG4105DCG PHP domain protein BAMEG_4832 ENOG4105C5S asparaginyl-tRNA synthetase BAMEG_4833 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAMEG_4835 ENOG4108RWN rrna methyltransferase BAMEG_4842 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAMEG_4843 ENOG4105CW7 secretion protein, HlyD family BAMEG_4844 ENOG4108JGH Tetr family transcriptional regulator BAMEG_4845 ENOG4105CN9 Peptidase m42 family protein BAMEG_4849 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAMEG_4851 ENOG4105C22 threonyL-tRNA synthetase BAMEG_4852 ENOG4108TDW sporulation protein YtxC BAMEG_4856 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAMEG_4858 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAMEG_4859 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAMEG_4861 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAMEG_4862 ENOG4105C2M dna polymerase I BAMEG_4863 ENOG4105BZU Histidine kinase BAMEG_4864 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_4869 ENOG4108HMX isocitrate dehydrogenase (NADP) BAMEG_4870 ENOG4105BZN citrate synthase BAMEG_4872 ENOG4108REF Sporulation integral membrane protein ytvi BAMEG_4873 ENOG4105FS0 cytoplasmic membrane protein BAMEG_4878 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAMEG_4879 ENOG4105C6K Malic enzyme BAMEG_4880 ENOG4105C0B DNA polymerase III (alpha subunit) BAMEG_4882 ENOG4105VV2 BAMEG_4884 ENOG4105SFS phosphoesterase RecJ domain protein BAMEG_4893 ENOG4105DC7 peptidase M24 BAMEG_4900 ENOG4105Z7P Acetyltransferase (GNAT) family BAMEG_4901 ENOG41082W1 Cupin 2, conserved barrel domain protein BAMEG_4903 ENOG4105VZ8 Transcriptional regulator BAMEG_4907 ENOG4107YZX Universal stress protein BAMEG_4916 ENOG4108JYZ YitT family BAMEG_4920 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAMEG_4922 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAMEG_4923 ENOG4105KBJ sporulation protein ytfj BAMEG_4926 ENOG4105EFZ amidohydrolase BAMEG_4928 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAMEG_4934 ENOG4106KR7 LysR family Transcriptional regulator BAMEG_4936 ENOG4105U5Y Transcriptional regulator BAMEG_4937 ENOG4105U5Y Transcriptional regulator BAMEG_4939 ENOG4105C28 cystathionine BAMEG_4943 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAMEG_4945 ENOG4105EMN RNA polymerase sigma factor BAMEG_4948 ENOG4105F1V Acetoin utilization protein BAMEG_4949 ENOG4105W87 Cbs domain BAMEG_4950 ENOG4105DGU Histone deacetylase BAMEG_4952 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAMEG_4954 ENOG4107SNB ankyrin repeat protein YahD BAMEG_4955 ENOG4105EP9 oxidoreductase BAMEG_4961 ENOG4105ETE Transcriptional regulator (LacI family BAMEG_4965 ENOG4105C88 aminopeptidase BAMEG_4973 ENOG4108VDD TRNA binding domain protein BAMEG_4979 ENOG4105C8F Beta-lactamase domain protein BAMEG_4982 ENOG4108V15 phosphotransferase enzyme family BAMEG_4983 ENOG4108IUM Glycogen debranching enzyme BAMEG_4985 ENOG4107QSE Dipeptidase BAMEG_4986 ENOG4107QSE Dipeptidase BAMEG_4987 ENOG4105YW5 deoR family transcriptional regulator BAMEG_4990 ENOG4105CBX hi0933 family BAMEG_4998 ENOG4108VJ1 Transcriptional regulator (CarD family BAMEG_4999 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BAMEG_5000 ENOG4105CSC Glucose uptake protein BAMEG_5003 ENOG4108ZAF Molybdopterin BAMEG_5004 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAMEG_5005 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAMEG_5007 ENOG4105D06 uba thif-type nad fad binding protein BAMEG_5008 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAMEG_5009 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAMEG_5013 ENOG41085GJ domain protein BAMEG_5015 ENOG4105DWV Homoserine O-trans-acetylase BAMEG_5019 ENOG4108B31 Spore germination protein BAMEG_5026 ENOG410605W Major Facilitator BAMEG_5027 ENOG4107S91 Sodium hydrogen exchanger BAMEG_5028 ENOG4105NCW Trka-c domain protein BAMEG_5031 ENOG4105C19 ABC transporter BAMEG_5035 ENOG4105N5T Radical SAM Protein BAMEG_5037 ENOG4105DA5 (ABC) transporter BAMEG_5043 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAMEG_5045 ENOG4108Z0R Transferase BAMEG_5046 ENOG4105YVM Phosphoesterase, PA-phosphatase related BAMEG_5047 ENOG4105BZF Glycosyl transferase (Group 1 BAMEG_5049 ENOG4108RIR Molybdenum cofactor biosynthesis protein BAMEG_5062 ENOG4105EGD dinuclear metal center protein, YbgI family BAMEG_5063 ENOG4105BZU Histidine kinase BAMEG_5064 ENOG4105BZU Histidine kinase BAMEG_5065 ENOG4107S9D Alpha beta hydrolase BAMEG_5066 ENOG4107T7U Sulfatase BAMEG_5070 ENOG4105D2X ABC transporter substrate-binding protein BAMEG_5072 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAMEG_5075 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAMEG_5082 ENOG4108V2W Carbonate dehydratase BAMEG_5084 ENOG4105C4M (Ubiquinol oxidase) subunit I BAMEG_5085 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAMEG_5095 ENOG41087YS Phage shock protein A BAMEG_5102 ENOG4105BZU Histidine kinase BAMEG_5103 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_5108 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAMEG_5109 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAMEG_5116 ENOG4107ZTW SNARE associated Golgi BAMEG_5119 ENOG4105C19 ABC transporter BAMEG_5120 ENOG41086D8 Transcriptional regulator BAMEG_5130 ENOG4105C6Z Gluconate BAMEG_5131 ENOG4105FDP GntR family transcriptional regulator BAMEG_5135 ENOG41069H0 dihydroorotase EC 3.5.2.3 BAMEG_5141 ENOG4105DTQ mandelate racemase muconate lactonizing BAMEG_5143 ENOG4108IPT Naphthoate synthase BAMEG_5144 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAMEG_5145 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAMEG_5146 ENOG4105E4F Isochorismate synthase BAMEG_5147 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAMEG_5149 ENOG4105VEQ Cold shock protein BAMEG_5153 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BAMEG_5155 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BAMEG_5157 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAMEG_5184 ENOG4105KT7 mgtC SapB transporter BAMEG_5186 ENOG4107PBV potassium channel BAMEG_5187 ENOG4107QYV phosphohexose isomerase BAMEG_5188 ENOG4105WG9 Conserved Protein BAMEG_5190 ENOG4105CHM Aminotransferase BAMEG_5191 ENOG4108ZB6 transcriptional regulator AsnC family BAMEG_5192 ENOG4105C5I Dehydrogenase BAMEG_5193 ENOG4108MUZ hydrolase BAMEG_5195 ENOG4105C87 Aminotransferase class I and II BAMEG_5198 ENOG4105Y38 Kinase-associated protein B BAMEG_5200 ENOG4107R3E Citrate transporter BAMEG_5204 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BAMEG_5205 ENOG4105KA0 thioesterase Superfamily protein BAMEG_5209 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAMEG_5214 ENOG41069ER domain protein BAMEG_5217 ENOG4105CEP NADH dehydrogenase BAMEG_5223 ENOG4105EWC Purine nucleoside phosphorylase BAMEG_5227 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAMEG_5232 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAMEG_5233 ENOG4105C4B ABC transporter, permease BAMEG_5234 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BAMEG_5243 ENOG41083MR nifu domain-containing protein BAMEG_5246 ENOG4108W5N phosphatidylglycerophosphatase a BAMEG_5248 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAMEG_5249 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAMEG_5252 ENOG4105CBT Fructose-1,6-bisphosphatase BAMEG_5255 ENOG4105MMD transcriptional regulator BAMEG_5256 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BAMEG_5257 ENOG4107TXC Transcriptional regulator BAMEG_5258 ENOG41090T1 Membrane BAMEG_5263 ENOG4105FAA peptidase M23 BAMEG_5265 ENOG4105KZD Domain of unknown function (DUF1805) BAMEG_5270 ENOG4105DIW FeS assembly protein SUFB BAMEG_5271 ENOG4108UNV SUF system FeS assembly protein, NifU family BAMEG_5272 ENOG4105C9B Cysteine desulfurase BAMEG_5273 ENOG4105JRK feS assembly protein SufD BAMEG_5274 ENOG4105C3K feS assembly ATPase SufC BAMEG_5275 ENOG4105D01 (LipO)protein BAMEG_5276 ENOG4105D01 (LipO)protein BAMEG_5277 ENOG4108UMI ABC transporter, permease BAMEG_5285 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAMEG_5294 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAMEG_5299 ENOG4108W8B Beta-lactamase domain protein BAMEG_5300 ENOG4105C1G acyl-Coa dehydrogenase BAMEG_5302 ENOG4105CHU acetyl-coa acetyltransferase BAMEG_5305 ENOG4105DZ1 carboxypeptidase BAMEG_5309 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAMEG_5313 ENOG4108SUT Major Facilitator Superfamily BAMEG_5314 ENOG4107R7I amino acid BAMEG_5316 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAMEG_5318 ENOG4107AYK membrAne BAMEG_5325 ENOG4107ZTW SNARE associated Golgi BAMEG_5327 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BAMEG_5328 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_5329 ENOG4105BZU Histidine kinase BAMEG_5331 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAMEG_5334 ENOG4105VG1 fes assembly suf system protein BAMEG_5335 ENOG4105D4Y metalloprotease BAMEG_5339 ENOG4107S91 Sodium hydrogen exchanger BAMEG_5340 ENOG4105NCW Trka-c domain protein BAMEG_5342 ENOG4108RMU ferritin dps family protein BAMEG_5346 ENOG4108URH decarboxylase BAMEG_5351 ENOG4105D9N nucleoside BAMEG_5352 ENOG4105D9N nucleoside BAMEG_5355 ENOG4108RYK Nad-dependent epimerase dehydratase BAMEG_5360 ENOG4105CV8 reductase BAMEG_5361 ENOG4105F27 Major Facilitator BAMEG_5362 ENOG4105KVH Transcriptional regulator BAMEG_5365 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAMEG_5366 ENOG4105D4A Cell wall formation (By similarity) BAMEG_5368 ENOG4105C8Q Methyl-accepting chemotaxis BAMEG_5370 ENOG4105WMR Protein CrcB homolog BAMEG_5371 ENOG4105WMR Protein CrcB homolog BAMEG_5374 ENOG4108MK9 spermidine N(1)-acetyltransferase BAMEG_5375 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BAMEG_5379 ENOG4108IPW abc transporter atp-binding protein BAMEG_5380 ENOG4105CM4 permease protein BAMEG_5388 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAMEG_5390 ENOG4105XZU Preprotein translocase, subunit SecG BAMEG_5391 ENOG41067MG lrgb family BAMEG_5411 ENOG4105EFC phage portal protein HK97 family BAMEG_5416 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAMEG_5418 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAMEG_5419 ENOG4105CP7 Triose-phosphate isomerase BAMEG_5424 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_5428 ENOG41090VF Stage v sporulation protein ac BAMEG_5429 ENOG4105CZ3 stage V sporulation protein ad BAMEG_5432 ENOG4105H67 Protein of unknown function (DUF421) BAMEG_5433 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAMEG_5434 ENOG4105KRI phosphocarrier protein (HPr BAMEG_5436 ENOG4105CHW UPF0052 protein BAMEG_5438 ENOG4108Z4K mutator MutT protein BAMEG_5440 ENOG4105C3M thioredoxin reductase BAMEG_5442 ENOG4108S4C acetyltransferase BAMEG_5446 ENOG41086DT Membrane protein of unknown function BAMEG_5448 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAMEG_5449 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAMEG_5450 ENOG4105D7V transposase BAMEG_5453 ENOG4107TXC Transcriptional regulator BAMEG_5458 ENOG4105HMI Membrane BAMEG_5459 ENOG4105DUM transcriptional regulator, lysR family BAMEG_5461 ENOG4108WS4 fmn reductase BAMEG_5464 ENOG4105BZ1 (ABC) transporter BAMEG_5466 ENOG4105CN1 protease BAMEG_5467 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAMEG_5468 ENOG4105CAK Cell division ATP-binding protein ftsE BAMEG_5472 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAMEG_5473 ENOG4105MS2 ribosomal subunit Interface protein BAMEG_5475 ENOG4105VEQ Cold shock protein BAMEG_5476 ENOG41081UC Inherit from COG: Competence protein BAMEG_5479 ENOG4105KVH Transcriptional regulator BAMEG_5481 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAMEG_5482 ENOG4108KGH TRANSCRIPTIONal BAMEG_5483 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAMEG_5484 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAMEG_5485 ENOG4105ESV Glycosyl transferase, family 4 BAMEG_5487 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAMEG_5490 ENOG410901P UPF0249 protein BAMEG_5491 ENOG4105F8D glycoside hydrolase family 4 BAMEG_5492 ENOG4105VCP PTS System BAMEG_5493 ENOG4105CK1 PTS System BAMEG_5495 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAMEG_5496 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAMEG_5497 ENOG4105VCP PTS System BAMEG_5499 ENOG4105VZJ PTS System BAMEG_5502 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BAMEG_5503 ENOG4105ECB domain protein BAMEG_5504 ENOG4107RSM transcriptional regulator BAMEG_5513 ENOG4105DAA L-lactate BAMEG_5515 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BAMEG_5517 ENOG4105E0M Sulfatase BAMEG_5524 ENOG4107R8N Glycosyl transferase, family 2 BAMEG_5526 ENOG4105C94 Transporter BAMEG_5527 ENOG41069ER domain protein BAMEG_5532 ENOG4105KBK Zinc finger, swim domain protein BAMEG_5533 ENOG4105C0D helicase BAMEG_5539 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAMEG_5541 ENOG4107RBB ABC transporter, permease BAMEG_5542 ENOG4105C19 ABC transporter BAMEG_5546 ENOG4105CXY transporter BAMEG_5549 ENOG4105BZU Histidine kinase BAMEG_5550 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_5551 ENOG4105CMR udp-glucose 4-epimerase BAMEG_5555 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAMEG_5556 ENOG4105EY8 ABC transporter BAMEG_5567 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAMEG_5570 ENOG4105FRN stage II sporulation protein BAMEG_5573 ENOG4105DY9 regulatoR BAMEG_5574 ENOG4108IUW ABC transporter BAMEG_5578 ENOG4106778 Protein of unknown function (DUF1146) BAMEG_5579 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAMEG_5580 ENOG4105C8S subunit m BAMEG_5581 ENOG4105D65 subunit l BAMEG_5586 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAMEG_5587 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAMEG_5589 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAMEG_5590 ENOG4105BZU Histidine kinase BAMEG_5600 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAMEG_5601 ENOG41062M3 atp synthase BAMEG_5607 ENOG4108YZG isomerase BAMEG_5610 ENOG4108VGI doxx family BAMEG_5611 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAMEG_5614 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAMEG_5616 ENOG4108ZXQ stage ii sporulation protein r BAMEG_5617 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAMEG_5618 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAMEG_5621 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAMEG_5622 ENOG4105CBT Fructose-1,6-bisphosphatase BAMEG_5623 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAMEG_5630 ENOG4105C1G acyl-Coa dehydrogenase BAMEG_5631 ENOG4105C1G acyl-Coa dehydrogenase BAMEG_5632 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAMEG_5634 ENOG4105DF6 Fe-S oxidoreductase BAMEG_5637 ENOG4105BZU Histidine kinase BAMEG_5642 ENOG4105BZU Histidine kinase BAMEG_5643 ENOG4105KCT ABC transporter BAMEG_5644 ENOG4108M15 ABC transporter BAMEG_5645 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAMEG_5650 ENOG4105IIU Aminopeptidase BAMEG_5654 ENOG4105EMN RNA polymerase sigma factor BAMEG_5656 ENOG410684U Domain of unknown function (DUF1934) BAMEG_5661 ENOG4105CYW agmatinase BAMEG_5663 ENOG4105DXB Major Facilitator superfamily BAMEG_5664 ENOG4107SWG transcriptional regulator MERR family BAMEG_5666 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAMEG_5667 ENOG4105BZ4 penicillin-binding protein BAMEG_5668 ENOG4108XFG YwhD family BAMEG_5669 ENOG4108Z4T Peptidase M50 BAMEG_5670 ENOG41069HH 4-oxalocrotonate tautomerase BAMEG_5671 ENOG4105DCI Phosphohydrolase BAMEG_5672 ENOG4108MES Periplasmic binding protein BAMEG_5673 ENOG4105E0A ABC, transporter BAMEG_5674 ENOG4105EHG Permease protein BAMEG_5675 ENOG4105DQ5 transport system permease protein BAMEG_5676 ENOG4105DQ5 transport system permease protein BAMEG_5678 ENOG4108VCI transcription factor, rsfa family BAMEG_5681 ENOG4108IJ2 phosphate acetyltransferase BAMEG_5684 ENOG4108VKI Cell wall hydrolase BAMEG_5688 ENOG4107SVH Potassium channel protein BAMEG_5690 ENOG410667J hydrolase BAMEG_5691 ENOG4105VCH membrane BAMEG_5693 ENOG4108TU7 Inherit from COG: (ABC) transporter BAMEG_5694 ENOG4105CJ1 ABC, transporter BAMEG_5695 ENOG41090WU lipolytic protein G-D-S-L family BAMEG_5698 ENOG4105D6E homoserine dehydrogenase BAMEG_5704 ENOG4108Y4K DNA-binding transcriptional activator BAMEG_5706 ENOG4105WH1 Two component transcriptional regulator luxr family BAMEG_5707 ENOG4105BZU Histidine kinase BAMEG_5708 ENOG4105BZU Histidine kinase BAMEG_5709 ENOG4105DWF phosphomethylpyrimidine kinase BAMEG_5710 ENOG4105BZU Histidine kinase BAMEG_5711 ENOG4105VCD cytoplasmic protein BAMEG_5712 ENOG4105D22 carbon starvation protein BAMEG_5713 ENOG4105DY9 regulatoR BAMEG_5714 ENOG41079KZ Major Facilitator Superfamily BAMEG_5719 ENOG4105EN6 Membrane BAMEG_5720 ENOG4106YBV Methyl-accepting chemotaxis BAMEG_5722 ENOG4108S4H thioesterase Superfamily protein BAMEG_5724 ENOG4105JEU Glycosyl transferase, family 2 BAMEG_5725 ENOG4105C5H ABC transporter BAMEG_5730 ENOG4105CKK Glycosyl transferase, family 2 BAMEG_5731 ENOG41067SE Tetr family transcriptional regulator BAMEG_5733 ENOG4105E0X reductase BAMEG_5735 ENOG4106F5Q Membrane BAMEG_5738 ENOG4105DY9 regulatoR BAMEG_5739 ENOG4108HRK Histidine kinase BAMEG_5741 ENOG4107RGD Major Facilitator superfamily BAMEG_5744 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAMEG_5746 ENOG4105IW1 AmiS UreI transporter BAMEG_5748 ENOG4105CMR udp-glucose 4-epimerase BAMEG_5749 ENOG4108UT2 hemolysin iii BAMEG_5751 ENOG4105C1J atp-dependent rna helicase BAMEG_5754 ENOG4105DPN Oligoendopeptidase f BAMEG_5758 ENOG4105C0H protease BAMEG_5759 ENOG4105Q2H domain protein BAMEG_5762 ENOG4105BZU Histidine kinase BAMEG_5763 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAMEG_5769 ENOG4105CDU Replicative dna helicase BAMEG_5771 ENOG4105BZR domain protein BAMEG_5772 ENOG4108XMW Membrane BAMEG_5774 ENOG4108UUM single-stranded DNA-binding protein BAMEG_5776 ENOG4105C3G gtp-binding protein BAMEG_5777 ENOG4105VDK protein, conserved in bacteria BAMEG_5778 ENOG4105D8X mechanosensitive ion channel BAMEG_5779 ENOG4108ZDA Sporulation protein YyaC BAMEG_5780 ENOG4105FA0 parb-like partition protein BAMEG_5781 ENOG4107QJE Chromosome Partitioning Protein BAMEG_5785 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAMEG_5787 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAMEG_A0013 ENOG4105EKQ RNA-directed DNA polymerase BAMEG_A0034 ENOG4105EKQ RNA-directed DNA polymerase BAMEG_A0048 ENOG4106JUT Streptomycin 3''-adenylyltransferase BAMEG_A0062 ENOG4105CNU cell division protein FtsK BAMEG_A0110 ENOG4105DHF Membrane BAMEG_A0116 ENOG4106AKK s-layer domain-containing protein BAMEG_A0117 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAMEG_A0122 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAMEG_A0123 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAMEG_A0126 ENOG4105DQ6 Transposase BAMEG_A0127 ENOG4105DQ6 Transposase BAMEG_A0138 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BAMEG_A0143 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAMEG_A0172 ENOG4105KRN Transcriptional regulator, abrb family BAMEG_A0174 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAMEG_A0182 ENOG4108IBT Inherit from COG: transposase BAMEG_A0184 ENOG4105DQ6 Transposase BAMEG_A0187 ENOG4105DQ6 Transposase BAMEG_A0188 ENOG4105DQ6 Transposase BAMEG_A0190 ENOG4108MEK Metal-binding protein YodA BAMEG_A0192 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BAMEG_A0199 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAMEG_B0004 ENOG4105K4H Nlp p60 protein BAMEG_B0042 ENOG4107QJE Chromosome Partitioning Protein BAMEG_B0049 ENOG4105DQ6 Transposase BAMEG_B0055 ENOG4105EWC Purine nucleoside phosphorylase BAMEG_B0077 ENOG4105C3F Signal peptidase i BAMEG_B0084 ENOG4105N14 lysine exporter protein LysE YggA BAMEG_B0092 ENOG4108J59 Extracellular solute-binding protein, family 5 BAMEG_B0096 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAMEG_B0107 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAMEG_B0108 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)