locus-tag class description BAPAT_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAPAT_0003 ENOG410848D S4 domain protein YaaA BAPAT_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAPAT_0009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BAPAT_0015 ENOG4105ZMH deoxynucleoside kinase BAPAT_0017 ENOG4105GTG Isochorismatase BAPAT_0018 ENOG4108Z6B deaminase BAPAT_0019 ENOG4105C6E dna polymerase iii BAPAT_0023 ENOG41067KS pro-sigma K processing BAPAT_0026 ENOG4105CXN decarboxylase BAPAT_0028 ENOG4105FA2 dna polymerase iii BAPAT_0029 ENOG4105MA4 psp1 domain protein BAPAT_0031 ENOG41060K3 Methyltransferase BAPAT_0033 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BAPAT_0034 ENOG4105KRN Transcriptional regulator, abrb family BAPAT_0036 ENOG4105F8V Hydrolase, tatD family BAPAT_0037 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BAPAT_0039 ENOG4105XFA sporulation peptidase YabG BAPAT_0040 ENOG4105W42 Veg protein BAPAT_0043 ENOG4105DFT pur operon repressor BAPAT_0044 ENOG4105KME endoribonuclease L-psp BAPAT_0047 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BAPAT_0048 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BAPAT_0050 ENOG4108JA2 transcriptioN-repair coupling factor BAPAT_0051 ENOG4108M14 stage v sporulation protein t BAPAT_0053 ENOG4108IY2 MazG family BAPAT_0054 ENOG41082I2 s4 domain protein BAPAT_0055 ENOG4105VYY sporulation protein yabp BAPAT_0058 ENOG41060GV RNA binding s1 domain protein BAPAT_0060 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BAPAT_0061 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAPAT_0062 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BAPAT_0065 ENOG4105C6T cysteine synthase BAPAT_0066 ENOG4105CRQ synthase (Component I) BAPAT_0067 ENOG4105DDQ anthranilate synthase BAPAT_0068 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BAPAT_0069 ENOG4105EEI dihydropteroate synthase BAPAT_0070 ENOG4105KRF dihydroneopterin aldolase BAPAT_0071 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BAPAT_0073 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BAPAT_0077 ENOG4108Z0C Uvrb UvrC protein BAPAT_0080 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BAPAT_0082 ENOG4105CTP PilT protein domain protein BAPAT_0086 ENOG4105D7W serine acetyltransferase BAPAT_0089 ENOG4105C2N RNA methyltransferase TrmH family group 3 BAPAT_0090 ENOG4105M0M Tetracycline resistance protein BAPAT_0091 ENOG4105QIV RNA polymerase BAPAT_0093 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BAPAT_0098 ENOG4107Y49 methyltransferase BAPAT_0100 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BAPAT_0101 ENOG4105XPM ribosomal protein BAPAT_0122 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BAPAT_0127 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAPAT_0129 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAPAT_0131 ENOG41067V7 50S ribosomal protein L36 BAPAT_0137 ENOG4108JJB ABC transporter BAPAT_0138 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAPAT_0139 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAPAT_0144 ENOG4105D1F ATP-binding protein BAPAT_0147 ENOG4108NMV polysaccharide deacetylase BAPAT_0153 ENOG4105C8B TIGR00159 family BAPAT_0154 ENOG4107U5W ybbr family BAPAT_0156 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BAPAT_0157 ENOG4108VQT Alpha beta hydrolase fold protein BAPAT_0159 ENOG4105CMG Carbohydrate kinase BAPAT_0161 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BAPAT_0162 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BAPAT_0169 ENOG4108PSK reductase BAPAT_0170 ENOG4108UMI ABC transporter, permease BAPAT_0171 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_0172 ENOG4105D01 (LipO)protein BAPAT_0173 ENOG4105EE1 crotonyl-CoA reductase BAPAT_0179 ENOG4105C2C drug resistance transporter, Bcr CflA BAPAT_0182 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPAT_0183 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPAT_0184 ENOG4105C3U ABC transporter BAPAT_0185 ENOG4108JQ7 (ABC) transporter BAPAT_0191 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPAT_0192 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPAT_0194 ENOG4105II7 pyrroline-5-carboxylate reductase BAPAT_0195 ENOG4107XDY Nicotinamide Mononucleotide Transporter BAPAT_0197 ENOG4105E0C molybdate abc transporter BAPAT_0198 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAPAT_0199 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BAPAT_0200 ENOG4105EGI Transcriptional regulator BAPAT_0203 ENOG4105F6E Acyl-transferase BAPAT_0205 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAPAT_0208 ENOG4108RE7 deoxyribonuclease BAPAT_0209 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BAPAT_0214 ENOG4105C5H ABC transporter BAPAT_0217 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BAPAT_0219 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPAT_0220 ENOG4105C3U ABC transporter BAPAT_0221 ENOG4108JQ7 (ABC) transporter BAPAT_0222 ENOG410667J hydrolase BAPAT_0227 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BAPAT_0228 ENOG4105ERH Fumarylacetoacetate hydrolase BAPAT_0230 ENOG4108SC4 )-transporter BAPAT_0231 ENOG4105CPF Cell wall formation (By similarity) BAPAT_0232 ENOG4105CPF Cell wall formation (By similarity) BAPAT_0233 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAPAT_0236 ENOG4107ZXI Rhomboid family BAPAT_0238 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BAPAT_0239 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAPAT_0241 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BAPAT_0245 ENOG4105K8N protein family UPF0079, ATPase BAPAT_0246 ENOG41072GX Peptidase M22 Glycoprotease BAPAT_0247 ENOG410801F ribosomal-protein-alanine acetyltransferase BAPAT_0248 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAPAT_0249 ENOG4105C5H ABC transporter BAPAT_0251 ENOG4108TYN CAAX amino terminal protease family protein BAPAT_0255 ENOG4105C7N Xanthine uracil vitamin C permease BAPAT_0257 ENOG4105BZU Histidine kinase BAPAT_0259 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPAT_0263 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_0266 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BAPAT_0267 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BAPAT_0268 ENOG4105C83 adenylosuccinate lyase BAPAT_0270 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BAPAT_0275 ENOG4108V3E phosphoribosylglycinamide formyltransferase BAPAT_0277 ENOG4105C12 Phosphoribosylglycinamide synthetase BAPAT_0282 ENOG4105C4R Atp-dependent dna helicase BAPAT_0288 ENOG4108W2Y isochorismatase BAPAT_0289 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_0290 ENOG4108UMI ABC transporter, permease BAPAT_0291 ENOG4105D01 (LipO)protein BAPAT_0294 ENOG4105D0U Arsenite-activated ATPase (ArsA) BAPAT_0295 ENOG410834F Transcriptional regulator BAPAT_0296 ENOG4107I77 yiaA/B two helix domain BAPAT_0300 ENOG4105CBD Diacylglycerol kinase BAPAT_0301 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BAPAT_0302 ENOG4108JPW Aminotransferase BAPAT_0304 ENOG4105C26 Dehydrogenase BAPAT_0305 ENOG4105KPY Small multidrug resistance protein BAPAT_0309 ENOG4105D9N nucleoside BAPAT_0310 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAPAT_0313 ENOG4108W15 Protein of unknown function (DUF1456) BAPAT_0316 ENOG4105DTQ mandelate racemase muconate lactonizing BAPAT_0318 ENOG4105DFD Na H antiporter BAPAT_0322 ENOG4105D3R alkyl hydroperoxide reductase BAPAT_0323 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BAPAT_0325 ENOG4107W7X Aldolase BAPAT_0326 ENOG4105EHG Permease protein BAPAT_0327 ENOG4105DQ5 transport system permease protein BAPAT_0328 ENOG4108V5C ABC transporter BAPAT_0333 ENOG4106UIA BAPAT_0337 ENOG4105BZU Histidine kinase BAPAT_0341 ENOG410756H nucleotidyltransferase BAPAT_0342 ENOG4105D2S major facilitator superfamily BAPAT_0345 ENOG4105E5Q amino acid AbC transporter BAPAT_0346 ENOG4105EAB amino acid AbC transporter BAPAT_0348 ENOG4105C8Q Methyl-accepting chemotaxis BAPAT_0349 ENOG4105C8Q Methyl-accepting chemotaxis BAPAT_0351 ENOG4105CI1 PTS System BAPAT_0358 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BAPAT_0361 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAPAT_0364 ENOG4105C5H ABC transporter BAPAT_0370 ENOG41062JF Transcriptional regulator BAPAT_0374 ENOG4105DEU major facilitator superfamily BAPAT_0377 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) BAPAT_0380 ENOG4108N0M stress protein BAPAT_0381 ENOG4106FN3 tellurium resistance protein BAPAT_0382 ENOG4106FN3 tellurium resistance protein BAPAT_0383 ENOG4107TS3 membrane protein, TerC BAPAT_0384 ENOG4108TTB tellurium resistance protein BAPAT_0388 ENOG4105KJF protein tyrosine phosphatase BAPAT_0390 ENOG4107U9T Pfam:Ribonuclease_BN BAPAT_0391 ENOG4105C59 p-type ATPase BAPAT_0392 ENOG4108IPJ Membrane BAPAT_0394 ENOG4105C3F Signal peptidase i BAPAT_0397 ENOG4107ZTW SNARE associated Golgi BAPAT_0400 ENOG410606W general stress protein BAPAT_0401 ENOG4105UPD Calcium Proton BAPAT_0409 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BAPAT_0410 ENOG4105VTR Integrase BAPAT_0464 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BAPAT_0466 ENOG4108JUB Transcriptional regulator BAPAT_0468 ENOG4108IQI permease BAPAT_0474 ENOG4105CSV Glutaminase BAPAT_0477 ENOG4108A04 Beta-lactamase BAPAT_0480 ENOG4105CKK Glycosyl transferase, family 2 BAPAT_0482 ENOG4107QQG Dehydrogenase BAPAT_0483 ENOG4105C3I Nad-dependent epimerase dehydratase BAPAT_0486 ENOG4105F1A Pyruvate formate-lyase BAPAT_0490 ENOG4105CI2 imidazolone-5-propionate hydrolase BAPAT_0491 ENOG4105ECP epimerase BAPAT_0497 ENOG41067AE Membrane-bound metal-dependent hydrolase BAPAT_0498 ENOG4105CEN a g-specific adenine glycosylase BAPAT_0499 ENOG4106BXE BAPAT_0504 ENOG4105BZ1 (ABC) transporter BAPAT_0505 ENOG4107NBY Membrane BAPAT_0506 ENOG4105CBC glutamate synthase BAPAT_0508 ENOG4108IUW ABC transporter BAPAT_0512 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAPAT_0513 ENOG4105G5W regulator Fur family BAPAT_0520 ENOG4108JQC penicillin-binding protein 1A BAPAT_0521 ENOG4107ZQN disulfide bond BAPAT_0522 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BAPAT_0524 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BAPAT_0525 ENOG4105BZU Histidine kinase BAPAT_0526 ENOG4105CYN Serine protein kinase BAPAT_0531 ENOG4105C94 Transporter BAPAT_0534 ENOG4105DZ6 Band 7 protein BAPAT_0536 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BAPAT_0537 ENOG4108MRH transcriptional regulatory protein BAPAT_0538 ENOG4105D4T Citrate transporter BAPAT_0542 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAPAT_0543 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_0544 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BAPAT_0545 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BAPAT_0547 ENOG4105BZ7 extracellular solute-binding protein family 1 BAPAT_0548 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BAPAT_0549 ENOG4108STX response regulator BAPAT_0550 ENOG4105US7 Histidine kinase BAPAT_0555 ENOG4108MRH transcriptional regulatory protein BAPAT_0557 ENOG4105C6K Malic enzyme BAPAT_0559 ENOG4108UZ3 Transporter BAPAT_0560 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAPAT_0562 ENOG4105BZU Histidine kinase BAPAT_0563 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_0565 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAPAT_0566 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAPAT_0567 ENOG4108JB9 formate dehydrogenase BAPAT_0572 ENOG4105CUB amino acid BAPAT_0574 ENOG4105C59 p-type ATPase BAPAT_0575 ENOG4105DAP Nicotinate phosphoribosyltransferase BAPAT_0582 ENOG41073R8 VanW family BAPAT_0583 ENOG4108KGH TRANSCRIPTIONal BAPAT_0584 ENOG4105D9N nucleoside BAPAT_0585 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BAPAT_0586 ENOG4105C37 (CBS) domain BAPAT_0587 ENOG4108IJ0 Aspartate ammonia-lyase BAPAT_0588 ENOG4105DAA L-lactate BAPAT_0591 ENOG4105DUX Transporter BAPAT_0592 ENOG4108MES Periplasmic binding protein BAPAT_0593 ENOG4105DQ5 transport system permease protein BAPAT_0594 ENOG4108IHU transport system permease protein BAPAT_0595 ENOG4105E0A ABC, transporter BAPAT_0596 ENOG4105DMQ Methyltransferase BAPAT_0598 ENOG4105EXW epimerase dehydratase BAPAT_0600 ENOG4107T89 von Willebrand factor, type A BAPAT_0601 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BAPAT_0602 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPAT_0605 ENOG4105BZU Histidine kinase BAPAT_0606 ENOG4105D5Q Arginine ornithine antiporter BAPAT_0607 ENOG4107414 GntR family transcriptional regulator BAPAT_0608 ENOG4105C5Y PTS System BAPAT_0609 ENOG4105CG3 alpha amylase, catalytic region BAPAT_0612 ENOG4105E1K spore germination protein BAPAT_0614 ENOG4105CRN Aminoglycoside phosphotransferase BAPAT_0615 ENOG4105BZG amino acid carrier protein BAPAT_0616 ENOG4105CDA abc transporter atp-binding protein BAPAT_0617 ENOG4105CT1 (ABC) transporter BAPAT_0618 ENOG4105EAD ABC transporter BAPAT_0619 ENOG4105DRP amino acid AbC transporter BAPAT_0620 ENOG4108IQI permease BAPAT_0625 ENOG4105D29 Helix-turn-helix type 11 domain protein BAPAT_0626 ENOG4105NAE bifunctional deaminase-reductase domain protein BAPAT_0627 ENOG4105BZU Histidine kinase BAPAT_0630 ENOG4105CHH sulfate transporter BAPAT_0631 ENOG41068KF Universal stress protein BAPAT_0633 ENOG4105DEF Extracellular solute-binding protein, family 5 BAPAT_0635 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPAT_0636 ENOG4108JQ7 (ABC) transporter BAPAT_0638 ENOG4105CXY transporter BAPAT_0639 ENOG41067TZ transcriptional regulator, MarR family BAPAT_0640 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_0641 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_0642 ENOG4105ETE Transcriptional regulator (LacI family BAPAT_0643 ENOG4108RVA ribokinase BAPAT_0645 ENOG4105C2J ABC transporter BAPAT_0646 ENOG4105CNN ABC, transporter BAPAT_0647 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BAPAT_0648 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAPAT_0660 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPAT_0661 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAPAT_0662 ENOG41069ER domain protein BAPAT_0663 ENOG4105VZ8 Transcriptional regulator BAPAT_0664 ENOG4107D63 BAPAT_0666 ENOG4105DUX Transporter BAPAT_0670 ENOG4105C85 amino acid BAPAT_0671 ENOG4105C7N Xanthine uracil vitamin C permease BAPAT_0679 ENOG4105BZ9 Cytochrome C oxidase, subunit I BAPAT_0680 ENOG4105E2S oxidase) subunit II BAPAT_0683 ENOG4106CAD Protein of unknown function (DUF3311) BAPAT_0684 ENOG4105E1V na solute symporter BAPAT_0687 ENOG4108NHD germination protein BAPAT_0688 ENOG4105CE1 Ferrous iron transport protein b BAPAT_0689 ENOG4105CE1 Ferrous iron transport protein b BAPAT_0690 ENOG4105CE1 Ferrous iron transport protein b BAPAT_0691 ENOG4105CVA phosphate BAPAT_0692 ENOG4105C8U phosphate abc transporter BAPAT_0693 ENOG4105E2Z phosphate ABC transporter (Permease BAPAT_0697 ENOG41080XQ Signal transduction protein with cbs domains BAPAT_0701 ENOG4105ETU transcriptional activator (TenA BAPAT_0703 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BAPAT_0705 ENOG4108VEU Thiamine monophosphate synthase BAPAT_0706 ENOG41080HI glycine oxidase BAPAT_0709 ENOG4105D06 uba thif-type nad fad binding protein BAPAT_0710 ENOG4105DWF phosphomethylpyrimidine kinase BAPAT_0718 ENOG4108INS Transcriptional regulator BAPAT_0721 ENOG4105C7N Xanthine uracil vitamin C permease BAPAT_0723 ENOG4108PXI ErfK YbiS YcfS YnhG BAPAT_0726 ENOG4105C5Y PTS System BAPAT_0733 ENOG4108B31 Spore germination protein BAPAT_0734 ENOG4108B31 Spore germination protein BAPAT_0738 ENOG4107Y03 Nitroreductase BAPAT_0739 ENOG4105ED1 spovr family BAPAT_0744 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BAPAT_0745 ENOG4105XTG Pfam:DUF156 BAPAT_0746 ENOG4105VFE sira family BAPAT_0747 ENOG4107TPS domain protein BAPAT_0748 ENOG4105VFE sira family BAPAT_0749 ENOG41085GJ domain protein BAPAT_0751 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BAPAT_0752 ENOG41087NI Sulfite exporter TauE/SafE BAPAT_0754 ENOG4108KGH TRANSCRIPTIONal BAPAT_0759 ENOG4105EMD TRANSCRIPTIONal BAPAT_0760 ENOG4105VCP PTS System BAPAT_0761 ENOG4105VZJ PTS System BAPAT_0765 ENOG41069ER domain protein BAPAT_0766 ENOG4107RBB ABC transporter, permease BAPAT_0767 ENOG4105C19 ABC transporter BAPAT_0774 ENOG4105WEF catalase BAPAT_0781 ENOG4107T5V SNARE associated Golgi BAPAT_0788 ENOG4105CUB amino acid BAPAT_0789 ENOG4107RWR Sodium hydrogen exchanger BAPAT_0791 ENOG4106KNT transcriptional regulator BAPAT_0798 ENOG4108PCN EamA-like transporter family BAPAT_0799 ENOG4108YXU transcriptional regulator AsnC family BAPAT_0801 ENOG4105KPY Small multidrug resistance protein BAPAT_0802 ENOG4105KPY Small multidrug resistance protein BAPAT_0807 ENOG4105NF4 modulator of drug activity BAPAT_0808 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAPAT_0809 ENOG410605W Major Facilitator BAPAT_0812 ENOG4107RKG DJ-1/PfpI family BAPAT_0813 ENOG4105CH6 catalase BAPAT_0815 ENOG4105D5Q Arginine ornithine antiporter BAPAT_0816 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BAPAT_0818 ENOG4105C26 Dehydrogenase BAPAT_0819 ENOG4105BZ1 (ABC) transporter BAPAT_0820 ENOG4105BZ1 (ABC) transporter BAPAT_0821 ENOG4105BZ1 (ABC) transporter BAPAT_0823 ENOG4105DRP amino acid AbC transporter BAPAT_0824 ENOG4105CDA abc transporter atp-binding protein BAPAT_0827 ENOG410839P BAPAT_0834 ENOG4107FQX Alpha-acetolactate decarboxylase BAPAT_0839 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPAT_0841 ENOG4105D4P Coproporphyrinogen iii oxidase BAPAT_0844 ENOG4105CHH sulfate transporter BAPAT_0852 ENOG4106AKK s-layer domain-containing protein BAPAT_0854 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPAT_0855 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPAT_0858 ENOG4105CGU Enoyl-CoA hydratase BAPAT_0861 ENOG4105DER m42 family BAPAT_0865 ENOG4105CTU Proline racemase BAPAT_0875 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPAT_0878 ENOG4108JQ7 (ABC) transporter BAPAT_0884 ENOG4105CSH Transporter BAPAT_0886 ENOG4108MRH transcriptional regulatory protein BAPAT_0895 ENOG4105CDU Replicative dna helicase BAPAT_0902 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_0913 ENOG4108IG5 Transcriptional regulator BAPAT_0917 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAPAT_0921 ENOG4105CMT Dihydroxyacetone kinase BAPAT_0923 ENOG4105CMT Dihydroxyacetone kinase BAPAT_0924 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAPAT_0925 ENOG410847I Transcriptional regulator, BadM Rrf2 family BAPAT_0931 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BAPAT_0943 ENOG4105WN5 stage II sporulation protein BAPAT_0945 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_0947 ENOG4108MJI response regulator BAPAT_0948 ENOG4105BZU Histidine kinase BAPAT_0949 ENOG4105BZU Histidine kinase BAPAT_0954 ENOG4105K8R UPF0145 protein BAPAT_0959 ENOG4107VRP DNA repair exonuclease BAPAT_0960 ENOG4106D4I domain protein BAPAT_0961 ENOG4105D7V transposase BAPAT_0964 ENOG4108IND Tetr family transcriptional regulator BAPAT_0965 ENOG4105EQ0 Major Facilitator superfamily BAPAT_0970 ENOG4108MUZ hydrolase BAPAT_0975 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BAPAT_0978 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BAPAT_0980 ENOG4105EMN RNA polymerase sigma factor BAPAT_0985 ENOG4105C57 major facilitator superfamily BAPAT_0986 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_0988 ENOG4105EEM helicase BAPAT_0989 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPAT_0994 ENOG4105K59 histidine triad (HIT) protein BAPAT_1001 ENOG410905X membrane-flanked domain protein BAPAT_1003 ENOG4105CKV Membrane BAPAT_1011 ENOG410905X membrane-flanked domain protein BAPAT_1012 ENOG4105CKV Membrane BAPAT_1013 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BAPAT_1014 ENOG4105BZ4 penicillin-binding protein BAPAT_1015 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BAPAT_1017 ENOG4105C1Q protoporphyrinogen oxidase BAPAT_1022 ENOG4105NA0 Transcriptional regulator BAPAT_1025 ENOG4105ECB domain protein BAPAT_1031 ENOG4106AXD BAPAT_1032 ENOG4108RQ5 Beta-lactamase domain-containing protein BAPAT_1033 ENOG4105DF9 Lipoate-protein, ligase BAPAT_1035 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_1041 ENOG4105CNA YD repeat protein BAPAT_1050 ENOG4105ENX hydrolase BAPAT_1052 ENOG4107RN3 metallophosphoesterase BAPAT_1053 ENOG4107TVP HD domain protein BAPAT_1055 ENOG4108AEY RNA polymerase sigma factor BAPAT_1056 ENOG41086D8 Transcriptional regulator BAPAT_1059 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_1064 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BAPAT_1065 ENOG4105C8Q Methyl-accepting chemotaxis BAPAT_1070 ENOG4105ZU5 s-layer protein BAPAT_1071 ENOG4107QP3 malate synthase g BAPAT_1074 ENOG4105VEQ Cold shock protein BAPAT_1077 ENOG4105XVF Competence transcription factor BAPAT_1080 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination BAPAT_1081 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BAPAT_1089 ENOG4105ERH Fumarylacetoacetate hydrolase BAPAT_1094 ENOG4105CAQ asparagine synthetase BAPAT_1095 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BAPAT_1096 ENOG4105CH6 catalase BAPAT_1097 ENOG4105BZU Histidine kinase BAPAT_1101 ENOG4105QNR S1 RNA binding domain protein BAPAT_1103 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPAT_1105 ENOG4107AYK membrAne BAPAT_1106 ENOG41073B9 BAPAT_1108 ENOG4108KP7 hydrolase BAPAT_1111 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BAPAT_1116 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPAT_1117 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BAPAT_1120 ENOG4105C31 Tryptophanyl-tRNA synthetase BAPAT_1123 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BAPAT_1124 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPAT_1126 ENOG4108JQ7 (ABC) transporter BAPAT_1127 ENOG4105UQX Mate efflux family protein BAPAT_1132 ENOG4108ZCF integral membrane protein BAPAT_1134 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPAT_1136 ENOG4105DPN Oligoendopeptidase f BAPAT_1139 ENOG4108Z18 K06886 hemoglobin BAPAT_1140 ENOG4105MIX Adenylate cyclase BAPAT_1143 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BAPAT_1144 ENOG4105EMS pseudouridine synthase BAPAT_1147 ENOG4105CNI cell division protein FtsW BAPAT_1149 ENOG4105K64 Glycosyl transferase, family 2 BAPAT_1153 ENOG4107TVC Glycosyl transferase, family 2 BAPAT_1157 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BAPAT_1158 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BAPAT_1160 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BAPAT_1170 ENOG4108WVJ 2'-5' rna ligase BAPAT_1175 ENOG4105CK7 Sodium proline symporter BAPAT_1177 ENOG4105CRQ synthase (Component I) BAPAT_1178 ENOG4105DDQ anthranilate synthase BAPAT_1196 ENOG4105C7S Dehydrogenase BAPAT_1198 ENOG4105VZ8 Transcriptional regulator BAPAT_1207 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BAPAT_1209 ENOG4105DZ1 carboxypeptidase BAPAT_1210 ENOG4105VFR signal peptidase BAPAT_1216 ENOG4105C26 Dehydrogenase BAPAT_1217 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_1218 ENOG4105F38 ABC transporter, permease BAPAT_1219 ENOG4105D38 putrescine abc transporter BAPAT_1220 ENOG4107RUE extracellular solute-binding protein family 1 BAPAT_1222 ENOG4105EYF MMPL domain protein BAPAT_1224 ENOG4108YBP pseudouridine synthase BAPAT_1226 ENOG4105K4I Scp-like extracellular BAPAT_1227 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BAPAT_1228 ENOG4105CQB FAD linked oxidase domain protein BAPAT_1231 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_1232 ENOG4105BZU Histidine kinase BAPAT_1233 ENOG4105JXH GntR family transcriptional regulator BAPAT_1237 ENOG4106A3R peptidase BAPAT_1239 ENOG4108QTI )-transporter BAPAT_1240 ENOG4107TS3 membrane protein, TerC BAPAT_1242 ENOG4105CZN Potassium uptake protein BAPAT_1243 ENOG410681C small acid-soluble spore protein BAPAT_1244 ENOG4108Z7G MaoC domain protein dehydratase BAPAT_1248 ENOG4105CHR reductase BAPAT_1250 ENOG4105MWK D-amino acid dehydrogenase, small subunit BAPAT_1254 ENOG4105C4Y ABC transporter BAPAT_1255 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_1257 ENOG4107RCV ABC transporter, permease BAPAT_1258 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BAPAT_1262 ENOG4105E98 transcriptional regulator DeoR family BAPAT_1267 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAPAT_1268 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BAPAT_1270 ENOG4105PXI polysaccharide deacetylase BAPAT_1272 ENOG4105BZU Histidine kinase BAPAT_1273 ENOG41090MY MarR family Transcriptional regulator BAPAT_1275 ENOG4106DF1 BAPAT_1277 ENOG4105BZU Histidine kinase BAPAT_1279 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BAPAT_1280 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BAPAT_1288 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BAPAT_1289 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPAT_1291 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPAT_1292 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BAPAT_1293 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAPAT_1294 ENOG4105CZV ABC transporter BAPAT_1296 ENOG4105CJ1 ABC, transporter BAPAT_1304 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAPAT_1305 ENOG4105EA8 2-Nitropropane dioxygenase BAPAT_1306 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAPAT_1308 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BAPAT_1313 ENOG4105NQC Flavodoxin BAPAT_1320 ENOG4107QMU Mate efflux family protein BAPAT_1321 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BAPAT_1327 ENOG4105CZN Potassium uptake protein BAPAT_1328 ENOG41063Y9 BAPAT_1329 ENOG4105KBJ sporulation protein ytfj BAPAT_1333 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAPAT_1334 ENOG4105C7K acetolactate synthase BAPAT_1335 ENOG4108ZP8 Acetolactate synthase small subunit BAPAT_1336 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAPAT_1338 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BAPAT_1343 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BAPAT_1350 ENOG4107RVV histidinol phosphate phosphatase, hisj family BAPAT_1353 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BAPAT_1354 ENOG4105E0M Sulfatase BAPAT_1356 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BAPAT_1360 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BAPAT_1361 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BAPAT_1363 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAPAT_1364 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAPAT_1365 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAPAT_1366 ENOG4105C8J )-transporter BAPAT_1370 ENOG4105DFD Na H antiporter BAPAT_1374 ENOG4105ENE Histidine kinase BAPAT_1375 ENOG4105WH1 Two component transcriptional regulator luxr family BAPAT_1378 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BAPAT_1383 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BAPAT_1387 ENOG4105CJ3 phosphate transporter BAPAT_1388 ENOG4107GRR phosphate transport regulator BAPAT_1389 ENOG4105BZ4 penicillin-binding protein BAPAT_1393 ENOG4105BZU Histidine kinase BAPAT_1394 ENOG4105I3N Conserved Protein BAPAT_1397 ENOG4105BZU Histidine kinase BAPAT_1404 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPAT_1405 ENOG4105DZ1 carboxypeptidase BAPAT_1406 ENOG4108JIC nucleoside recognition domain protein BAPAT_1408 ENOG4105FE9 pseudouridine synthase BAPAT_1410 ENOG4107TWT Cytochrome c biogenesis protein BAPAT_1411 ENOG4105CRE cytochrome C BAPAT_1412 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_1413 ENOG4105BZU Histidine kinase BAPAT_1414 ENOG4108WBT adenosyltransferase BAPAT_1417 ENOG4108SAX Membrane BAPAT_1419 ENOG4105T7X BAPAT_1420 ENOG4105C9U ATP-dependent DNA helicase RecQ BAPAT_1421 ENOG4105I7S Abortive infection protein BAPAT_1423 ENOG4107RGJ metallophosphoesterase BAPAT_1424 ENOG4107RGJ metallophosphoesterase BAPAT_1425 ENOG4107X2D transcriptional regulator, merr family BAPAT_1426 ENOG4108S6Z Negative regulator of genetic competence BAPAT_1431 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BAPAT_1432 ENOG4107RB3 L-asparaginase BAPAT_1438 ENOG4105S2F BAPAT_1439 ENOG41065D1 BAPAT_1445 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BAPAT_1448 ENOG4105XXQ heptaprenyl diphosphate synthase component I BAPAT_1450 ENOG4105EAH synthase BAPAT_1454 ENOG4105CIH Imidazole acetol-phosphate transaminase BAPAT_1455 ENOG41068YB TPR repeat-containing protein BAPAT_1458 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BAPAT_1459 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BAPAT_1460 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BAPAT_1466 ENOG4108JYZ YitT family BAPAT_1467 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BAPAT_1470 ENOG4105FJR Lmbe family BAPAT_1471 ENOG4105CPK Glycosyl transferase (Group 1 BAPAT_1480 ENOG4105YAC BAPAT_1484 ENOG4105CSM endonuclease III BAPAT_1486 ENOG4105BZ4 penicillin-binding protein BAPAT_1497 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BAPAT_1499 ENOG4105DVT helicase BAPAT_1500 ENOG4105CTD carboxy-peptidase BAPAT_1503 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BAPAT_1506 ENOG4105C2W permease BAPAT_1507 ENOG4105DHF Membrane BAPAT_1509 ENOG410890F Dynamin family BAPAT_1511 ENOG4108W0I acetyltransferase BAPAT_1513 ENOG4105KHC sulfurtransferase BAPAT_1516 ENOG4106032 Glutathionylspermidine synthase BAPAT_1531 ENOG4105CPK Glycosyl transferase (Group 1 BAPAT_1534 ENOG4108SZE gCN5-related N-acetyltransferase BAPAT_1538 ENOG41081VK Ribonuclease BAPAT_1551 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPAT_1553 ENOG4107RWR Sodium hydrogen exchanger BAPAT_1554 ENOG4105CN5 Metallo-Beta-Lactamase BAPAT_1555 ENOG4108Z5V transcriptional regulator, merr family BAPAT_1557 ENOG4105H67 Protein of unknown function (DUF421) BAPAT_1559 ENOG41080C8 DUF218 domain BAPAT_1570 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAPAT_1572 ENOG4107R0U MotA TolQ exbB proton channel BAPAT_1573 ENOG4105ER2 Ompa motb domain protein BAPAT_1574 ENOG4107YTP response regulator receiver protein BAPAT_1575 ENOG4105CBS Chea signal transduction histidine kinase BAPAT_1576 ENOG4105CBS Chea signal transduction histidine kinase BAPAT_1577 ENOG4105DD5 Flagellar motor switch protein BAPAT_1580 ENOG4105BZU Histidine kinase BAPAT_1585 ENOG4105E1Q flagellar hook-associated protein BAPAT_1586 ENOG4105DTJ flagellar hook-associated protein BAPAT_1591 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BAPAT_1592 ENOG4108ZC9 flagellar basal-body rod protein flgc BAPAT_1593 ENOG41075Z6 flagellar hook-basal body complex protein fliE BAPAT_1594 ENOG4107U2N Flagellar M-ring protein BAPAT_1596 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAPAT_1604 ENOG4105BZE flagellar hook protein, FlgE BAPAT_1608 ENOG4107R88 Chemotaxis protein (CheV) BAPAT_1610 ENOG4105K64 Glycosyl transferase, family 2 BAPAT_1617 ENOG4107TVC Glycosyl transferase, family 2 BAPAT_1622 ENOG4105I03 Flagellin BAPAT_1623 ENOG4105E4C Lytic transglycosylase catalytic BAPAT_1625 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BAPAT_1627 ENOG4105DD5 Flagellar motor switch protein BAPAT_1629 ENOG4105CN7 Flagellar biosynthetic protein FliP BAPAT_1630 ENOG4105VS8 Flagellar biosynthetic protein fliq BAPAT_1632 ENOG4105D00 flagellar biosynthetic protein flhB BAPAT_1633 ENOG4105D7B Flagellar biosynthesis protein flha BAPAT_1636 ENOG4105KTQ flagellar basal-body rod protein BAPAT_1637 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPAT_1642 ENOG4108RZE Tetr family transcriptional regulator BAPAT_1645 ENOG4105KAC Antibiotic biosynthesis monooxygenase BAPAT_1652 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BAPAT_1653 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BAPAT_1654 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BAPAT_1655 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BAPAT_1663 ENOG4105CVJ phosphoglycerate mutase BAPAT_1670 ENOG4105CAQ asparagine synthetase BAPAT_1674 ENOG4105PGM cation diffusion facilitator family transporter BAPAT_1676 ENOG4105DRR Transcriptional regulator, GntR family BAPAT_1677 ENOG4108UZ3 Transporter BAPAT_1678 ENOG4105CKI cobalamin synthesis protein BAPAT_1679 ENOG4108PJD permease BAPAT_1683 ENOG4105DFD Na H antiporter BAPAT_1684 ENOG4105C9Q fumarate hydratase class II BAPAT_1688 ENOG4107QJQ Mate efflux family protein BAPAT_1689 ENOG4107QJQ Mate efflux family protein BAPAT_1690 ENOG4105EC3 peptidase S51, dipeptidase E BAPAT_1694 ENOG4107QIV Cytochrome c biogenesis protein BAPAT_1701 ENOG4106BRA Membrane BAPAT_1708 ENOG4105CJ1 ABC, transporter BAPAT_1712 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BAPAT_1714 ENOG4108IJ0 Aspartate ammonia-lyase BAPAT_1715 ENOG4108IJ0 Aspartate ammonia-lyase BAPAT_1716 ENOG4105C6K Malic enzyme BAPAT_1729 ENOG4105FVX BAPAT_1738 ENOG4105CSR polyphosphate kinase 2 BAPAT_1739 ENOG4105DXI Major Facilitator superfamily BAPAT_1742 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAPAT_1746 ENOG4105C6T cysteine synthase BAPAT_1747 ENOG4105C6T cysteine synthase BAPAT_1751 ENOG4105C8J )-transporter BAPAT_1753 ENOG4105X5K response regulator receiver protein BAPAT_1754 ENOG4105H67 Protein of unknown function (DUF421) BAPAT_1757 ENOG4106KE4 Dehydrogenase BAPAT_1760 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BAPAT_1761 ENOG4105CHR reductase BAPAT_1762 ENOG4105CM2 brancheD-chain amino acid aminotransferase BAPAT_1763 ENOG4105C7K acetolactate synthase BAPAT_1764 ENOG4108ZP8 Acetolactate synthase small subunit BAPAT_1765 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BAPAT_1767 ENOG4105C7B Threonine dehydratase BAPAT_1774 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BAPAT_1776 ENOG4105DY9 regulatoR BAPAT_1777 ENOG4105CYC Transferase BAPAT_1781 ENOG4105F6J Alpha beta hydrolase fold BAPAT_1782 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPAT_1788 ENOG41068WN BAPAT_1793 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BAPAT_1794 ENOG4105C72 UPF0176 protein BAPAT_1796 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BAPAT_1798 ENOG4105C0X amino acid BAPAT_1799 ENOG4105C0X amino acid BAPAT_1804 ENOG4107RHR regulatoR BAPAT_1806 ENOG4105D9N nucleoside BAPAT_1807 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BAPAT_1814 ENOG4107RAQ aminopeptidase BAPAT_1815 ENOG4107STQ Multicopper oxidase BAPAT_1826 ENOG4108T5E Copper resistance protein BAPAT_1827 ENOG4105KTB nuclear export factor GLE1 BAPAT_1829 ENOG4107RT3 EamA-like transporter family BAPAT_1830 ENOG4105GZI Transcriptional regulator BAPAT_1831 ENOG4108Z40 Transcriptional regulator BAPAT_1832 ENOG4107ZXU DSBA oxidoreductase BAPAT_1833 ENOG4108TVJ Nitroreductase BAPAT_1835 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAPAT_1836 ENOG4106F5Q Membrane BAPAT_1837 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPAT_1839 ENOG4105CKI cobalamin synthesis protein BAPAT_1843 ENOG4108Z7G MaoC domain protein dehydratase BAPAT_1844 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPAT_1846 ENOG4105C0Z ABC transporter BAPAT_1847 ENOG4108IV0 ABC, transporter BAPAT_1848 ENOG4105C32 Amino acid ABC transporter (Permease) BAPAT_1850 ENOG4105SKE transcriptional Regulator LysR family BAPAT_1854 ENOG4105YGB Transcriptional regulator BAPAT_1856 ENOG4105C4M (Ubiquinol oxidase) subunit I BAPAT_1857 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAPAT_1858 ENOG4108JJ9 ABC, transporter BAPAT_1859 ENOG4108JJ8 (ABC) transporter BAPAT_1867 ENOG4105BZ1 (ABC) transporter BAPAT_1868 ENOG4105BZ1 (ABC) transporter BAPAT_1869 ENOG4105EFI regulatoR BAPAT_1871 ENOG4105BZU Histidine kinase BAPAT_1875 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BAPAT_1876 ENOG4108ZJ4 polysaccharide deacetylase BAPAT_1881 ENOG4105D6E homoserine dehydrogenase BAPAT_1886 ENOG4108KGH TRANSCRIPTIONal BAPAT_1888 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_1889 ENOG4105BZU Histidine kinase BAPAT_1890 ENOG4107VMI polysaccharide deacetylase BAPAT_1892 ENOG4105KT7 mgtC SapB transporter BAPAT_1893 ENOG4105VRR gCN5-related N-acetyltransferase BAPAT_1895 ENOG4105DUU IucA IucC family protein BAPAT_1896 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_1899 ENOG4108WBH protein TIM barrel BAPAT_1900 ENOG4105YWU small acid-soluble spore protein BAPAT_1902 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BAPAT_1913 ENOG4105KRN Transcriptional regulator, abrb family BAPAT_1915 ENOG4105YVS arsR family transcriptional regulator BAPAT_1916 ENOG4107SET aldo keto reductase BAPAT_1917 ENOG4107XZQ multidrug resistance protein BAPAT_1922 ENOG4105C8Q Methyl-accepting chemotaxis BAPAT_1925 ENOG4108K88 Membrane BAPAT_1926 ENOG4108WPJ Ferritin-like domain BAPAT_1929 ENOG4105DEN Luciferase family BAPAT_1933 ENOG4107QM2 Aldo Keto reductase BAPAT_1934 ENOG4105CKI cobalamin synthesis protein BAPAT_1944 ENOG4105DSE periplasmic solute binding protein BAPAT_1946 ENOG4105K4T epimerase BAPAT_1948 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAPAT_1953 ENOG4105CVJ phosphoglycerate mutase BAPAT_1957 ENOG4107T5V SNARE associated Golgi BAPAT_1960 ENOG4108PJD permease BAPAT_1962 ENOG4108S4H thioesterase Superfamily protein BAPAT_1963 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BAPAT_1968 ENOG4105SXS Protein of unknown function (DUF456) BAPAT_1969 ENOG4105C37 (CBS) domain BAPAT_1973 ENOG4108Z7R Chaperone CsaA BAPAT_1975 ENOG4108ZRV stage ii sporulation protein p BAPAT_1977 ENOG4108VXD carboxy-peptidase BAPAT_1979 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BAPAT_1984 ENOG4108X4Q Hydrolase BAPAT_1986 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BAPAT_1987 ENOG4107RBS Methyltransferase BAPAT_1990 ENOG41087PP glycosyltransferase MGT family BAPAT_1991 ENOG4108JYZ YitT family BAPAT_1992 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BAPAT_1999 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BAPAT_2007 ENOG4105KBJ sporulation protein ytfj BAPAT_2012 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BAPAT_2017 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BAPAT_2018 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_2020 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BAPAT_2021 ENOG4105EMN RNA polymerase sigma factor BAPAT_2026 ENOG4108V06 Glutathione peroxidase BAPAT_2029 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPAT_2033 ENOG4108IUE nitrate reductase beta subunit BAPAT_2034 ENOG4105R3A Nitrate reductase BAPAT_2039 ENOG4107V6Q Cyclic nucleotide-binding domain BAPAT_2040 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAPAT_2041 ENOG4105D06 uba thif-type nad fad binding protein BAPAT_2042 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPAT_2043 ENOG4108ZAF Molybdopterin BAPAT_2048 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BAPAT_2049 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BAPAT_2050 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BAPAT_2051 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BAPAT_2052 ENOG4108IFG nitrite reductase, (NAD(P)H) BAPAT_2053 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BAPAT_2061 ENOG4105MCT stage V sporulation protein S BAPAT_2064 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPAT_2069 ENOG4105C5H ABC transporter BAPAT_2072 ENOG4108UUM single-stranded DNA-binding protein BAPAT_2074 ENOG41061H0 Monooxygenase BAPAT_2078 ENOG4107YX5 Pfam:DUF548 BAPAT_2079 ENOG4105C75 arginyL-tRNA synthetase BAPAT_2084 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAPAT_2087 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BAPAT_2088 ENOG4105C5S asparaginyl-tRNA synthetase BAPAT_2092 ENOG4105EC2 ftsk spoIIIe BAPAT_2110 ENOG4105BZW Glycerate kinase BAPAT_2111 ENOG4107QPK )-transporter BAPAT_2112 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_2113 ENOG41062D9 Histidine kinase BAPAT_2116 ENOG4105C8J )-transporter BAPAT_2120 ENOG4107XGZ Hydrolase BAPAT_2121 ENOG4105CY2 Citrate transporter BAPAT_2122 ENOG4105C0A alcohol dehydrogenase BAPAT_2125 ENOG4105KD7 acetyltransferase BAPAT_2127 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BAPAT_2133 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BAPAT_2137 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BAPAT_2140 ENOG4107RVG penicillin-binding protein BAPAT_2141 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BAPAT_2142 ENOG4105E9Q Acyl-transferase BAPAT_2143 ENOG4108UT2 hemolysin iii BAPAT_2145 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BAPAT_2147 ENOG4108RCR degv family BAPAT_2148 ENOG4105E8R UPF0173 metal-dependent hydrolase BAPAT_2149 ENOG4108KF3 Electron transport protein SCO1 SenC BAPAT_2150 ENOG4107Y70 Heat shock protein BAPAT_2151 ENOG4105CAQ asparagine synthetase BAPAT_2154 ENOG4108MES Periplasmic binding protein BAPAT_2155 ENOG4105F0I Aminotransferase BAPAT_2162 ENOG4105D8X mechanosensitive ion channel BAPAT_2163 ENOG4105BZU Histidine kinase BAPAT_2164 ENOG4105WH1 Two component transcriptional regulator luxr family BAPAT_2166 ENOG4106KNT transcriptional regulator BAPAT_2173 ENOG4105CMG Carbohydrate kinase BAPAT_2174 ENOG4105CMG Carbohydrate kinase BAPAT_2180 ENOG4108IJ8 ABC transporter BAPAT_2181 ENOG4105E90 ABC transporter BAPAT_2188 ENOG4105C37 (CBS) domain BAPAT_2194 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPAT_2197 ENOG4107S4Y M20 DapE family protein YgeY BAPAT_2198 ENOG4108TSC N-acetyltransferase BAPAT_2199 ENOG4108JUB Transcriptional regulator BAPAT_2200 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BAPAT_2208 ENOG4108N23 SpoOM-related protein BAPAT_2209 ENOG410841Q phosphoesterase PA-phosphatase related protein BAPAT_2211 ENOG4105SZ6 Thioredoxin BAPAT_2214 ENOG4108IBT Inherit from COG: transposase BAPAT_2232 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BAPAT_2239 ENOG4105BZ4 penicillin-binding protein BAPAT_2240 ENOG4105CZM Major Facilitator BAPAT_2241 ENOG4105W8X HesB YadR YfhF-family protein BAPAT_2243 ENOG4105DXD 2-methylcitrate dehydratase BAPAT_2244 ENOG4105CR4 methylisocitrate lyase BAPAT_2246 ENOG4105C1G acyl-Coa dehydrogenase BAPAT_2247 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPAT_2249 ENOG4105N14 lysine exporter protein LysE YggA BAPAT_2250 ENOG4105E39 Enoyl-CoA hydratase BAPAT_2253 ENOG4107RFY SbcCD D subunit BAPAT_2254 ENOG4105EYH Exonuclease BAPAT_2260 ENOG4105FCD Major Facilitator BAPAT_2261 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BAPAT_2262 ENOG4105E4F Isochorismate synthase BAPAT_2263 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BAPAT_2264 ENOG4105WQI isochorismatase BAPAT_2265 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_2266 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_2267 ENOG4105WQT MbtH domain protein BAPAT_2268 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_2271 ENOG4105K70 DNA-binding protein BAPAT_2275 ENOG4105BZG amino acid carrier protein BAPAT_2276 ENOG4105BZG amino acid carrier protein BAPAT_2280 ENOG4105FE9 pseudouridine synthase BAPAT_2282 ENOG4105C22 threonyL-tRNA synthetase BAPAT_2283 ENOG4105C19 ABC transporter BAPAT_2286 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAPAT_2292 ENOG4108D32 Methyltransferase BAPAT_2298 ENOG41081I9 integral membrane protein BAPAT_2300 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAPAT_2302 ENOG4105EYF MMPL domain protein BAPAT_2307 ENOG4105WCN acetyltransferase BAPAT_2313 ENOG4105C1Q protoporphyrinogen oxidase BAPAT_2315 ENOG41068WN BAPAT_2317 ENOG4105VEQ Cold shock protein BAPAT_2321 ENOG410667J hydrolase BAPAT_2329 ENOG4107V2S Transcriptional regulator BAPAT_2330 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAPAT_2333 ENOG4105DND Transcriptional regulator BAPAT_2334 ENOG4108RPX mosc domain containing protein BAPAT_2337 ENOG4105BZ1 (ABC) transporter BAPAT_2338 ENOG4105BZ1 (ABC) transporter BAPAT_2341 ENOG4108JCI Transcriptional regulator BAPAT_2347 ENOG4108KPJ rna polymerase sigma factor BAPAT_2353 ENOG4105F32 YngK protein BAPAT_2358 ENOG4105RD7 BadF BadG BcrA BcrD BAPAT_2360 ENOG4107STF Involved in phosphonate degradation (By similarity) BAPAT_2364 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BAPAT_2367 ENOG4105C1J atp-dependent rna helicase BAPAT_2371 ENOG4108RZE Tetr family transcriptional regulator BAPAT_2376 ENOG41088CC tellurite resistance protein tehB BAPAT_2378 ENOG4108I0C methyltransferase BAPAT_2379 ENOG4107RA9 decarboxylase BAPAT_2380 ENOG41090HR transcriptional regulator BAPAT_2389 ENOG4105CIN aminoacyl-histidine dipeptidase BAPAT_2395 ENOG4107RF6 penicillin-binding protein BAPAT_2396 ENOG4107RF6 penicillin-binding protein BAPAT_2398 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAPAT_2399 ENOG4105ETE Transcriptional regulator (LacI family BAPAT_2400 ENOG4105IE8 Alpha-ketoglutarate permease BAPAT_2401 ENOG4105CK5 oxidoreductase BAPAT_2408 ENOG4105D2N Aldolase BAPAT_2413 ENOG4105CGH 5'-nucleotidase BAPAT_2417 ENOG4105VZ8 Transcriptional regulator BAPAT_2419 ENOG4108VXD carboxy-peptidase BAPAT_2423 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BAPAT_2424 ENOG41067SE Tetr family transcriptional regulator BAPAT_2425 ENOG4105C5H ABC transporter BAPAT_2427 ENOG4105BZU Histidine kinase BAPAT_2430 ENOG4106ANW SMI1_KNR4 BAPAT_2433 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BAPAT_2436 ENOG4105CJ1 ABC, transporter BAPAT_2438 ENOG4107Z3H Transcriptional regulator, TetR family BAPAT_2441 ENOG4105C1G acyl-Coa dehydrogenase BAPAT_2442 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAPAT_2443 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BAPAT_2444 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BAPAT_2445 ENOG4105E39 Enoyl-CoA hydratase BAPAT_2446 ENOG4107QX3 carboxylase BAPAT_2447 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAPAT_2449 ENOG4105WCN acetyltransferase BAPAT_2450 ENOG4105DBI uridine monophosphokinase BAPAT_2453 ENOG4105DZ1 carboxypeptidase BAPAT_2456 ENOG4105T9C HD domain BAPAT_2458 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BAPAT_2469 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPAT_2469 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPAT_2472 ENOG4105FQP Beta-lactamase BAPAT_2474 ENOG4107Y80 Major Facilitator superfamily BAPAT_2477 ENOG4105CUV Homoserine Kinase BAPAT_2484 ENOG4105CPQ Dehydrogenase BAPAT_2487 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPAT_2488 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPAT_2508 ENOG4105ETU transcriptional activator (TenA BAPAT_2530 ENOG410667J hydrolase BAPAT_2532 ENOG4105BZU Histidine kinase BAPAT_2533 ENOG4107RF6 penicillin-binding protein BAPAT_2537 ENOG4108JJB ABC transporter BAPAT_2540 ENOG4108HGU Histidine kinase BAPAT_2544 ENOG4105CB2 alcohol dehydrogenase BAPAT_2545 ENOG4105CJN penicillin-binding protein BAPAT_2547 ENOG4105FQP Beta-lactamase BAPAT_2554 ENOG4108V4B ThiJ pfpI BAPAT_2559 ENOG4107Y80 Major Facilitator superfamily BAPAT_2562 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAPAT_2567 ENOG4107Y9U Membrane BAPAT_2575 ENOG4105FCD Major Facilitator BAPAT_2577 ENOG4105E09 nadh pyrophosphatase BAPAT_2578 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BAPAT_2579 ENOG4108Z4K mutator MutT protein BAPAT_2586 ENOG4108XI2 Domain of unknown function (DUF1963) BAPAT_2592 ENOG4105KWG Pfam:DUF1696 BAPAT_2599 ENOG4105PKS Excinuclease abc c subunit domain protein BAPAT_2608 ENOG4107VFR oxidoreductase BAPAT_2613 ENOG4105PAD Hydrolase BAPAT_2617 ENOG4105DY8 decarboxylase BAPAT_2621 ENOG4108IUM Glycogen debranching enzyme BAPAT_2626 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BAPAT_2628 ENOG4105FDR Membrane BAPAT_2635 ENOG4108V3A UPF0421 protein BAPAT_2639 ENOG4105MSI germination protein ypeb BAPAT_2643 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) BAPAT_2644 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BAPAT_2645 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BAPAT_2646 ENOG4107Z3H Transcriptional regulator, TetR family BAPAT_2652 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BAPAT_2656 ENOG4105E98 transcriptional regulator DeoR family BAPAT_2660 ENOG41062ES Transcriptional regulator BAPAT_2665 ENOG4107QKR Dehydrogenase BAPAT_2667 ENOG4107RUY (E1 component), alpha subunit BAPAT_2669 ENOG4105E1F short-chain dehydrogenase reductase BAPAT_2670 ENOG4105RHY Pfam:UPF0157 BAPAT_2675 ENOG4107SQ8 Glycine betaine BAPAT_2676 ENOG4108IJ7 Glycine betaine BAPAT_2681 ENOG4105E66 phosphoriboisomerase A BAPAT_2682 ENOG41082BV acetyltransferase BAPAT_2683 ENOG4108M1A Chitin-binding protein BAPAT_2693 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAPAT_2699 ENOG4108Z7F N-acetyltransferase BAPAT_2703 ENOG4105EEM helicase BAPAT_2707 ENOG4105C9U ATP-dependent DNA helicase RecQ BAPAT_2716 ENOG4108M1A Chitin-binding protein BAPAT_2719 ENOG4105BZG amino acid carrier protein BAPAT_2720 ENOG4105C26 Dehydrogenase BAPAT_2721 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAPAT_2722 ENOG4105CTU Proline racemase BAPAT_2723 ENOG4105CTU Proline racemase BAPAT_2724 ENOG41080HI glycine oxidase BAPAT_2732 ENOG4107T5V SNARE associated Golgi BAPAT_2735 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BAPAT_2736 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BAPAT_2739 ENOG4105DTQ mandelate racemase muconate lactonizing BAPAT_2748 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BAPAT_2749 ENOG4105BZU Histidine kinase BAPAT_2750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_2757 ENOG4105DPN Oligoendopeptidase f BAPAT_2760 ENOG4105EPR degv family BAPAT_2768 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BAPAT_2769 ENOG4106K7D Major facilitator family transporter BAPAT_2773 ENOG4107BMA Transglycosylase associated protein BAPAT_2776 ENOG41089UC methyltransferase, type 11 BAPAT_2783 ENOG4105CHM Aminotransferase BAPAT_2789 ENOG4105DVE abc transporter atp-binding protein BAPAT_2796 ENOG4105C02 permease BAPAT_2798 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BAPAT_2799 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BAPAT_2800 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BAPAT_2805 ENOG4105E09 nadh pyrophosphatase BAPAT_2809 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BAPAT_2822 ENOG4107VMI polysaccharide deacetylase BAPAT_2824 ENOG4108ZCF integral membrane protein BAPAT_2825 ENOG4105E0M Sulfatase BAPAT_2826 ENOG4105C5H ABC transporter BAPAT_2828 ENOG4105EYF MMPL domain protein BAPAT_2829 ENOG4105EYF MMPL domain protein BAPAT_2830 ENOG41082JN Transcriptional regulator BAPAT_2834 ENOG4105CIH Imidazole acetol-phosphate transaminase BAPAT_2835 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BAPAT_2836 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BAPAT_2844 ENOG41069ER domain protein BAPAT_2847 ENOG4105EMN RNA polymerase sigma factor BAPAT_2852 ENOG4105D4B ABC, transporter BAPAT_2855 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BAPAT_2857 ENOG4105DKT Transcriptional regulator BAPAT_2858 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BAPAT_2860 ENOG41061GT Aldolase BAPAT_2864 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BAPAT_2870 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BAPAT_2872 ENOG4105II7 pyrroline-5-carboxylate reductase BAPAT_2874 ENOG4107258 Transcriptional regulator BAPAT_2876 ENOG4105E0Y RtcB Protein BAPAT_2877 ENOG4105ECK Fatty Acid Desaturase BAPAT_2878 ENOG4105G6Z alkaline phosphatase BAPAT_2880 ENOG4105VMP Transcriptional regulator BAPAT_2883 ENOG41090T1 Membrane BAPAT_2885 ENOG4108WCX response regulator BAPAT_2887 ENOG41068WN BAPAT_2893 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPAT_2898 ENOG4105CKK Glycosyl transferase, family 2 BAPAT_2902 ENOG4105CKK Glycosyl transferase, family 2 BAPAT_2904 ENOG4105C8Y Acetylornithine aminotransferase BAPAT_2913 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BAPAT_2915 ENOG4108TVJ Nitroreductase BAPAT_2916 ENOG4105FS7 Transcriptional regulator BAPAT_2925 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPAT_2927 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BAPAT_2933 ENOG4108XET gCN5-related N-acetyltransferase BAPAT_2950 ENOG410635A Membrane BAPAT_2951 ENOG4105KNA -acetyltransferase BAPAT_2952 ENOG4108IQI permease BAPAT_2954 ENOG4105F1N DNA alkylation repair BAPAT_2962 ENOG4107RF6 penicillin-binding protein BAPAT_2964 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BAPAT_2973 ENOG4105P4J Allophanate hydrolase, subunit 1 BAPAT_2974 ENOG4107258 Transcriptional regulator BAPAT_2976 ENOG4106N3A copper homeostasis protein cutc BAPAT_2977 ENOG4108ZRV stage ii sporulation protein p BAPAT_2978 ENOG4108ZHR arsR family transcriptional regulator BAPAT_2980 ENOG4105FDT acyl-CoA dehydrogenase BAPAT_2984 ENOG4105DWD nucleoside recognition domain protein BAPAT_2990 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BAPAT_3004 ENOG4105E2A Dehydrogenase BAPAT_3007 ENOG4108IJ0 Aspartate ammonia-lyase BAPAT_3008 ENOG4108IJ0 Aspartate ammonia-lyase BAPAT_3009 ENOG4105HDK L-asparaginase BAPAT_3010 ENOG4108IMY Transcriptional regulator BAPAT_3012 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BAPAT_3013 ENOG4105CUB amino acid BAPAT_3014 ENOG4105CUB amino acid BAPAT_3017 ENOG4105II7 pyrroline-5-carboxylate reductase BAPAT_3019 ENOG4105C6K Malic enzyme BAPAT_3021 ENOG4108NHD germination protein BAPAT_3022 ENOG4108Q8B Spore germination protein BAPAT_3028 ENOG4105CSV Glutaminase BAPAT_3035 ENOG4105CGH 5'-nucleotidase BAPAT_3036 ENOG4105CH6 catalase BAPAT_3038 ENOG4105CHJ isochorismatase hydrolase BAPAT_3043 ENOG41090MY MarR family Transcriptional regulator BAPAT_3050 ENOG4108606 TspO/MBR family BAPAT_3051 ENOG4105CVP deoxyribo-dipyrimidine photolyase BAPAT_3054 ENOG4108TWJ NADH dehydrogenase subunit 5 BAPAT_3055 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BAPAT_3057 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAPAT_3058 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BAPAT_3059 ENOG4105DSE periplasmic solute binding protein BAPAT_3060 ENOG4105CC5 ABC transporter BAPAT_3061 ENOG4105DIK (ABC) transporter BAPAT_3067 ENOG4105D6J arsenicaL-resistance protein BAPAT_3068 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_3069 ENOG41085FC arsR family transcriptional regulator BAPAT_3072 ENOG4105F7F Chaperone BAPAT_3074 ENOG4105CHR reductase BAPAT_3075 ENOG4108YXU transcriptional regulator AsnC family BAPAT_3089 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BAPAT_3090 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_3092 ENOG4105IIP Membrane BAPAT_3095 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_3096 ENOG41062D9 Histidine kinase BAPAT_3101 ENOG4105K6H D-cysteine desulfhydrase BAPAT_3107 ENOG4105VZ8 Transcriptional regulator BAPAT_3111 ENOG4108NNI Beta-lactamase domain-containing protein BAPAT_3112 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BAPAT_3114 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BAPAT_3115 ENOG4105JQZ Methyltransferase BAPAT_3118 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAPAT_3119 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BAPAT_3122 ENOG4105BZU Histidine kinase BAPAT_3125 ENOG4108U05 Transcriptional regulator BAPAT_3126 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAPAT_3127 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BAPAT_3129 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BAPAT_3130 ENOG4105DJB Major Facilitator Superfamily BAPAT_3131 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BAPAT_3132 ENOG4107QR9 Iron-sulfur cluster binding protein BAPAT_3134 ENOG4106P55 Transcriptional regulator BAPAT_3136 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BAPAT_3141 ENOG4105TRI Hydrolase BAPAT_3149 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPAT_3156 ENOG4107QJQ Mate efflux family protein BAPAT_3159 ENOG4105MZU cell filamentation protein BAPAT_3160 ENOG4105EQ0 Major Facilitator superfamily BAPAT_3161 ENOG4108JGH Tetr family transcriptional regulator BAPAT_3163 ENOG4105C44 Serine transporter BAPAT_3164 ENOG4105EJQ L-serine dehydratase BAPAT_3167 ENOG4108JPW Aminotransferase BAPAT_3173 ENOG4105DVH amino acid BAPAT_3176 ENOG4108JQ1 Dehydrogenase BAPAT_3180 ENOG4108AEY RNA polymerase sigma factor BAPAT_3183 ENOG41082W1 Cupin 2, conserved barrel domain protein BAPAT_3184 ENOG410874W AraC family transcriptional regulator BAPAT_3188 ENOG4105HIR S-layer domain protein BAPAT_3196 ENOG4108ISG Major Facilitator BAPAT_3199 ENOG4105CZM Major Facilitator BAPAT_3203 ENOG4105DA5 (ABC) transporter BAPAT_3204 ENOG41069JR BAPAT_3207 ENOG4105RXJ BAPAT_3208 ENOG4105KPY Small multidrug resistance protein BAPAT_3209 ENOG4105KBX Transcriptional regulator, TetR family BAPAT_3211 ENOG4105CRW Short chain fatty acid transporter BAPAT_3213 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAPAT_3220 ENOG4108JJB ABC transporter BAPAT_3221 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BAPAT_3226 ENOG4108K8S endonuclease I BAPAT_3229 ENOG41067QW Transcriptional regulator BAPAT_3231 ENOG4108Z66 YbaK ebsC protein BAPAT_3232 ENOG4105CUT histidyl-tRNA synthetase BAPAT_3235 ENOG4105KVH Transcriptional regulator BAPAT_3236 ENOG4108RCM Nitroreductase BAPAT_3240 ENOG4108PSK reductase BAPAT_3242 ENOG4105CJ1 ABC, transporter BAPAT_3254 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_3255 ENOG4105DKQ ROK family BAPAT_3256 ENOG4106UW1 Major Facilitator superfamily BAPAT_3257 ENOG4108UW5 maltose o-acetyltransferase BAPAT_3259 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BAPAT_3260 ENOG4105C31 Tryptophanyl-tRNA synthetase BAPAT_3261 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAPAT_3265 ENOG4105DMQ Methyltransferase BAPAT_3267 ENOG4105EV4 Multidrug resistance protein mdtH BAPAT_3274 ENOG4105C37 (CBS) domain BAPAT_3278 ENOG4105DDN Pentapeptide repeat-containing protein BAPAT_3279 ENOG4105XDF Protein of unknown function (DUF1272) BAPAT_3280 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BAPAT_3281 ENOG4105CMG Carbohydrate kinase BAPAT_3282 ENOG4105C6Z Gluconate BAPAT_3283 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BAPAT_3286 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAPAT_3287 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BAPAT_3288 ENOG4105CIS alcohol dehydrogenase BAPAT_3289 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BAPAT_3292 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BAPAT_3293 ENOG4105D4Y metalloprotease BAPAT_3297 ENOG4105CV8 reductase BAPAT_3298 ENOG4105F27 Major Facilitator BAPAT_3301 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BAPAT_3302 ENOG4105C44 Serine transporter BAPAT_3308 ENOG4105KVH Transcriptional regulator BAPAT_3309 ENOG4108TZY GntR Family Transcriptional Regulator BAPAT_3310 ENOG4105D9R oxidoreductase BAPAT_3311 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BAPAT_3312 ENOG4105KVH Transcriptional regulator BAPAT_3313 ENOG4105KVH Transcriptional regulator BAPAT_3320 ENOG4105JAB phenazine biosynthesis protein, phzf family BAPAT_3322 ENOG4105CHR reductase BAPAT_3326 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BAPAT_3327 ENOG4105KVH Transcriptional regulator BAPAT_3331 ENOG4108ZJ4 polysaccharide deacetylase BAPAT_3347 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BAPAT_3351 ENOG4107YXZ hydrolase, family 25 BAPAT_3356 ENOG4105ED2 Beta-lactamase BAPAT_3358 ENOG4105H3G oxidoreductase BAPAT_3365 ENOG4105CIS alcohol dehydrogenase BAPAT_3373 ENOG4108TN2 lmbE family BAPAT_3375 ENOG4107R3E Citrate transporter BAPAT_3380 ENOG4108MES Periplasmic binding protein BAPAT_3382 ENOG4105EHG Permease protein BAPAT_3383 ENOG4105DQ5 transport system permease protein BAPAT_3384 ENOG4105NX3 Membrane BAPAT_3385 ENOG4107ZY0 Phenazine biosynthesis-like protein BAPAT_3389 ENOG4107CUJ Protein of unknown function (DUF2690) BAPAT_3391 ENOG4107V2S Transcriptional regulator BAPAT_3395 ENOG4105C98 muts2 protein BAPAT_3400 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BAPAT_3401 ENOG4105DPN Oligoendopeptidase f BAPAT_3402 ENOG4108A04 Beta-lactamase BAPAT_3408 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BAPAT_3412 ENOG41082BM Transcriptional regulator, arsr family BAPAT_3413 ENOG4105CIS alcohol dehydrogenase BAPAT_3420 ENOG4105RHY Pfam:UPF0157 BAPAT_3422 ENOG4105C09 Bile acid BAPAT_3423 ENOG4105CQB FAD linked oxidase domain protein BAPAT_3427 ENOG4108UT6 Transferase hexapeptide repeat containing protein BAPAT_3429 ENOG4105K64 Glycosyl transferase, family 2 BAPAT_3430 ENOG4105E39 Enoyl-CoA hydratase BAPAT_3432 ENOG4105KT7 mgtC SapB transporter BAPAT_3434 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_3435 ENOG41073R8 VanW family BAPAT_3437 ENOG4108R1P BAPAT_3441 ENOG4105VEQ Cold shock protein BAPAT_3445 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BAPAT_3449 ENOG410904N short-chain dehydrogenase reductase BAPAT_3451 ENOG4106IQC argininosuccinate lyase BAPAT_3455 ENOG4108IA2 Sodium pantothenate symporter BAPAT_3457 ENOG4105C26 Dehydrogenase BAPAT_3458 ENOG4105CHR reductase BAPAT_3460 ENOG4105EWU Squalene--hopene cyclase BAPAT_3462 ENOG4105FR1 rard protein BAPAT_3463 ENOG410696E Membrane BAPAT_3466 ENOG4105D1F ATP-binding protein BAPAT_3468 ENOG4108ZAF Molybdopterin BAPAT_3469 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPAT_3470 ENOG4105D06 uba thif-type nad fad binding protein BAPAT_3471 ENOG4105TMB Formate nitrite transporter BAPAT_3473 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BAPAT_3474 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BAPAT_3476 ENOG4108JB9 formate dehydrogenase BAPAT_3477 ENOG4108JB9 formate dehydrogenase BAPAT_3478 ENOG4105E1K spore germination protein BAPAT_3489 ENOG4107QJT sodium dicarboxylate symporter BAPAT_3490 ENOG4108KGH TRANSCRIPTIONal BAPAT_3492 ENOG4105EMN RNA polymerase sigma factor BAPAT_3497 ENOG4105CIG ABC transporter BAPAT_3499 ENOG4105D9R oxidoreductase BAPAT_3501 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BAPAT_3502 ENOG4105K4P CoA-binding domain protein BAPAT_3503 ENOG4105C0H protease BAPAT_3504 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_3506 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BAPAT_3507 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BAPAT_3508 ENOG4105W8X HesB YadR YfhF-family protein BAPAT_3514 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAPAT_3515 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BAPAT_3517 ENOG4108JJA ABC, transporter BAPAT_3518 ENOG4108I0Z Aconitate hydratase BAPAT_3523 ENOG4105E5W Transporter BAPAT_3525 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPAT_3529 ENOG4107F3J Amp-dependent synthetase and ligase BAPAT_3530 ENOG4107ZYJ bioY protein BAPAT_3531 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_3540 ENOG4107AYK membrAne BAPAT_3542 ENOG4105BZU Histidine kinase BAPAT_3543 ENOG4105FBA Phospholipase Carboxylesterase BAPAT_3544 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BAPAT_3545 ENOG4105CK7 Sodium proline symporter BAPAT_3546 ENOG4105CBC glutamate synthase BAPAT_3547 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BAPAT_3548 ENOG4108VJ1 Transcriptional regulator (CarD family BAPAT_3549 ENOG4108903 Formimidoylglutamase BAPAT_3554 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BAPAT_3566 ENOG4107QIV Cytochrome c biogenesis protein BAPAT_3568 ENOG4107RSM transcriptional regulator BAPAT_3569 ENOG4105VAW lrga family BAPAT_3570 ENOG41067MG lrgb family BAPAT_3577 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BAPAT_3580 ENOG4105BZ1 (ABC) transporter BAPAT_3581 ENOG4105BZ1 (ABC) transporter BAPAT_3585 ENOG4105D7V transposase BAPAT_3588 ENOG4105D5T phosphonate abc transporter BAPAT_3591 ENOG4105CGH 5'-nucleotidase BAPAT_3593 ENOG4108SVB resolvase BAPAT_3597 ENOG4105K7K Transcriptional regulator BAPAT_3607 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BAPAT_3608 ENOG4105XSJ toxin secretion phage lysis holin BAPAT_3646 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BAPAT_3667 ENOG4105C5F glutamine synthetase BAPAT_3668 ENOG4105KV4 Transcriptional regulator BAPAT_3669 ENOG4105CXI aluminum resistance protein BAPAT_3670 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BAPAT_3671 ENOG4105EN6 Membrane BAPAT_3673 ENOG4106F1P AAA ATPase, central domain protein BAPAT_3679 ENOG41069ER domain protein BAPAT_3680 ENOG4105DM4 PTS System BAPAT_3681 ENOG4105DE4 1-phosphofructokinase BAPAT_3682 ENOG4105E98 transcriptional regulator DeoR family BAPAT_3683 ENOG4107QW4 alcohol dehydrogenase BAPAT_3684 ENOG4107QW4 alcohol dehydrogenase BAPAT_3685 ENOG4108SJC Membrane BAPAT_3688 ENOG4105C85 amino acid BAPAT_3692 ENOG4105TMB Formate nitrite transporter BAPAT_3693 ENOG4105K70 DNA-binding protein BAPAT_3694 ENOG4105C59 p-type ATPase BAPAT_3695 ENOG410681U heavy metal transport detoxification protein BAPAT_3696 ENOG4105VPX protein, conserved in bacteria BAPAT_3698 ENOG4105NIV Esterase BAPAT_3699 ENOG4105E0A ABC, transporter BAPAT_3707 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BAPAT_3708 ENOG4105D03 DNA-3-methyladenine glycosylase II BAPAT_3714 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_3715 ENOG4105BZU Histidine kinase BAPAT_3716 ENOG4105BZU Histidine kinase BAPAT_3721 ENOG41067MG lrgb family BAPAT_3724 ENOG4107TTQ Alpha beta hydrolase fold BAPAT_3725 ENOG4107YEI lmbE family BAPAT_3729 ENOG4105F0V Cell wall hydrolase BAPAT_3730 ENOG4107R6R udp-galactopyranose mutase BAPAT_3731 ENOG4105E0M Sulfatase BAPAT_3732 ENOG410890F Dynamin family BAPAT_3734 ENOG4107QHE Choloylglycine hydrolase BAPAT_3739 ENOG4105DA5 (ABC) transporter BAPAT_3744 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAPAT_3745 ENOG4105DQU oxidoreductase, subunit beta BAPAT_3746 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BAPAT_3747 ENOG4108IGT Dipeptidase BAPAT_3748 ENOG4105MCT stage V sporulation protein S BAPAT_3749 ENOG4105D48 metallophosphoesterase BAPAT_3754 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BAPAT_3757 ENOG4105XZV Protein of unknown function (DUF3243) BAPAT_3758 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BAPAT_3762 ENOG4105UIB (ABC) transporter BAPAT_3763 ENOG4105UIB (ABC) transporter BAPAT_3764 ENOG4108JQ9 ABC transporter BAPAT_3765 ENOG4105DIH basic membrane BAPAT_3766 ENOG4105FDP GntR family transcriptional regulator BAPAT_3767 ENOG4107QZI cell division protein FtsK BAPAT_3769 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BAPAT_3771 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BAPAT_3773 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BAPAT_3774 ENOG4108S0H Dipicolinic acid synthetase, b subunit BAPAT_3775 ENOG4105E35 Dipicolinate synthase subunit A BAPAT_3777 ENOG4105C1V Peptidase, M16 BAPAT_3780 ENOG4105DTN riboflavin biosynthesis protein ribF BAPAT_3781 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BAPAT_3783 ENOG4105W7A Protein of unknown function (DUF503) BAPAT_3785 ENOG4105VHM ribosomal protein BAPAT_3786 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BAPAT_3787 ENOG4105CHV Transcription elongation factor NusA BAPAT_3789 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BAPAT_3791 ENOG4105DZP Membrane-associated zinc metalloprotease BAPAT_3792 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BAPAT_3793 ENOG4105KNE Phosphatidate cytidylyltransferase BAPAT_3802 ENOG4108HE4 integrase family BAPAT_3804 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPAT_3807 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BAPAT_3810 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BAPAT_3815 ENOG4105VB6 UPF0109 protein BAPAT_3819 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BAPAT_3820 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BAPAT_3823 ENOG4105CHR reductase BAPAT_3824 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BAPAT_3827 ENOG4105CB5 ATP-dependent DNA helicase recG BAPAT_3828 ENOG4105DP4 dak2 domain fusion protein ylov BAPAT_3829 ENOG4108ZAA Alkaline-shock protein BAPAT_3831 ENOG4105FJ0 thiamine BAPAT_3832 ENOG4105DJV ribulose-phosphate 3-epimerase BAPAT_3833 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BAPAT_3834 ENOG4105D9P serine threonine protein kinase BAPAT_3835 ENOG4108ZF3 Phosphatase BAPAT_3837 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BAPAT_3839 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAPAT_3840 ENOG4105C25 Primosomal protein n' BAPAT_3841 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BAPAT_3845 ENOG4105DSJ YicC domain protein BAPAT_3847 ENOG4105F23 Fibronectin-binding protein BAPAT_3848 ENOG4105DC7 peptidase M24 BAPAT_3861 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BAPAT_3866 ENOG4105C34 Pseudouridine synthase BAPAT_3869 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BAPAT_3871 ENOG4105DBK s4 domain protein BAPAT_3872 ENOG41067XK integral membrane protein BAPAT_3874 ENOG4105DFA alanine racemase domain protein BAPAT_3875 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BAPAT_3876 ENOG4105WR5 sporulation protein, YlmC YmxH family BAPAT_3878 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_3880 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BAPAT_3881 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BAPAT_3882 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BAPAT_3883 ENOG4105D4A Cell wall formation (By similarity) BAPAT_3884 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAPAT_3885 ENOG4105CNI cell division protein FtsW BAPAT_3888 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BAPAT_3889 ENOG4105CJN penicillin-binding protein BAPAT_3890 ENOG4105CJN penicillin-binding protein BAPAT_3891 ENOG41068DC Essential cell division protein (By similarity) BAPAT_3898 ENOG4105KNH Nucleic acid-binding protein BAPAT_3909 ENOG4105XSJ toxin secretion phage lysis holin BAPAT_3926 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAPAT_3928 ENOG4105CAR Terminase, large subunit BAPAT_3945 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BAPAT_3957 ENOG4108IMY Transcriptional regulator BAPAT_3964 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BAPAT_3966 ENOG41063PX domain protein BAPAT_3967 ENOG4105D78 K07001 NTE family protein BAPAT_3968 ENOG4105H20 Sporulation integral membrane protein YlbJ BAPAT_3970 ENOG4106H78 methyltransferase BAPAT_3975 ENOG4107TB6 phosphoglycerate mutase BAPAT_3978 ENOG4106UY4 Inherit from COG: Scp-like extracellular BAPAT_3988 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BAPAT_3989 ENOG4105CNI cell division protein FtsW BAPAT_3992 ENOG4108IAB Phoh family BAPAT_3996 ENOG4105QA2 BAPAT_3997 ENOG4105CI3 gtp-binding protein typa BAPAT_3999 ENOG4105ECY inositol monophosphatase BAPAT_4003 ENOG4105CXN decarboxylase BAPAT_4012 ENOG4105CPP Dehydrogenase, E1 component BAPAT_4015 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BAPAT_4016 ENOG4108X4Q Hydrolase BAPAT_4018 ENOG4105CN5 Metallo-Beta-Lactamase BAPAT_4019 ENOG4107ZYR domain protein BAPAT_4026 ENOG4108XRC Protein of unknown function (DUF458) BAPAT_4028 ENOG4107IN1 Protein of unknown function (DUF1797) BAPAT_4031 ENOG4105EPM Diguanylate phosphodiesterase BAPAT_4032 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BAPAT_4038 ENOG4105UIN BAPAT_4050 ENOG4108HGU Histidine kinase BAPAT_4052 ENOG4105CHM Aminotransferase BAPAT_4053 ENOG4105FKQ transcriptional regulator BAPAT_4054 ENOG4105EG2 ABC transporter, permease BAPAT_4056 ENOG4107FKK extracellular solute-binding protein family 1 BAPAT_4058 ENOG4105CG3 alpha amylase, catalytic region BAPAT_4066 ENOG4105CHU acetyl-coa acetyltransferase BAPAT_4073 ENOG4105K7K Transcriptional regulator BAPAT_4074 ENOG4105DTD Dehydrogenase BAPAT_4076 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BAPAT_4078 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BAPAT_4083 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BAPAT_4086 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPAT_4087 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BAPAT_4088 ENOG4106TD9 Diguanylate cyclase BAPAT_4092 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BAPAT_4095 ENOG4105CID antiterminator BAPAT_4097 ENOG4105FDP GntR family transcriptional regulator BAPAT_4099 ENOG4105CE4 GlcNAc 6-P deacetylase BAPAT_4106 ENOG4107ZE5 PPIases accelerate the folding of proteins BAPAT_4107 ENOG4105PTM secreted protein BAPAT_4108 ENOG4105J7I hydrolase BAPAT_4110 ENOG4105G6R Stage v sporulation protein ae BAPAT_4112 ENOG4105CZ3 stage V sporulation protein ad BAPAT_4113 ENOG41090VF Stage v sporulation protein ac BAPAT_4117 ENOG4105C8J )-transporter BAPAT_4118 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_4120 ENOG41082AN stage II sporulation protein BAPAT_4121 ENOG4105DZ1 carboxypeptidase BAPAT_4122 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPAT_4123 ENOG4105DVE abc transporter atp-binding protein BAPAT_4130 ENOG4105D7N magnesium and cobalt transport protein CorA BAPAT_4135 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPAT_4137 ENOG4105I3K Ferric uptake regulator, Fur family BAPAT_4138 ENOG4105MZ9 stage II sporulation protein m BAPAT_4143 ENOG4105CPC Aldo Keto reductase BAPAT_4145 ENOG4105RHY Pfam:UPF0157 BAPAT_4149 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BAPAT_4151 ENOG4105ETE Transcriptional regulator (LacI family BAPAT_4152 ENOG4108YM7 Gcn5-related n-acetyltransferase BAPAT_4156 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BAPAT_4157 ENOG4108R6K riboflavin synthase, subunit alpha BAPAT_4161 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BAPAT_4162 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAPAT_4163 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BAPAT_4164 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BAPAT_4166 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BAPAT_4169 ENOG4105DFD Na H antiporter BAPAT_4170 ENOG4105CGH 5'-nucleotidase BAPAT_4178 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BAPAT_4181 ENOG4108IXY short-chain dehydrogenase reductase BAPAT_4182 ENOG41069FQ Metallo-beta-lactamase superfamily BAPAT_4183 ENOG4105II7 pyrroline-5-carboxylate reductase BAPAT_4184 ENOG4105EJQ L-serine dehydratase BAPAT_4189 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPAT_4190 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BAPAT_4191 ENOG4105D9U N-acetyltransferase BAPAT_4193 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BAPAT_4194 ENOG4108QEG Membrane BAPAT_4195 ENOG4105CDA abc transporter atp-binding protein BAPAT_4196 ENOG4105E5Q amino acid AbC transporter BAPAT_4197 ENOG4108HW3 (ABC) transporter BAPAT_4200 ENOG4105G7B Protein of unknown function (DUF2992) BAPAT_4201 ENOG4105E09 nadh pyrophosphatase BAPAT_4203 ENOG4105C7S Dehydrogenase BAPAT_4204 ENOG4105CPP Dehydrogenase, E1 component BAPAT_4208 ENOG4107RDP Dehydrogenase BAPAT_4210 ENOG4108JUB Transcriptional regulator BAPAT_4212 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAPAT_4215 ENOG4107QQR Sporulation BAPAT_4216 ENOG4105S1Z Stage IV sporulation protein B BAPAT_4217 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BAPAT_4219 ENOG4105DX0 Hemolysin A BAPAT_4221 ENOG4105CTB Polyprenyl synthetase BAPAT_4226 ENOG4108ZSR alkaline shock protein BAPAT_4227 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BAPAT_4231 ENOG410644B Stage III sporulation protein af BAPAT_4233 ENOG4105KQ4 Stage iii sporulation protein ad BAPAT_4234 ENOG4108CQH stage III sporulation protein AC BAPAT_4235 ENOG4105KR5 Stage iii sporulation protein BAPAT_4236 ENOG4105CD2 stage iii sporulation protein aa BAPAT_4240 ENOG4105DC7 peptidase M24 BAPAT_4243 ENOG4105CBJ Metal-dependent enzyme BAPAT_4245 ENOG4107YBY Hydrolase BAPAT_4250 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BAPAT_4251 ENOG4105WZW rhodanese family BAPAT_4255 ENOG41080TC multidrug resistance protein BAPAT_4262 ENOG4105CJ1 ABC, transporter BAPAT_4263 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BAPAT_4269 ENOG4105C0D helicase BAPAT_4282 ENOG4106855 Competence protein BAPAT_4294 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BAPAT_4298 ENOG4105C28 cystathionine BAPAT_4299 ENOG4105C28 cystathionine BAPAT_4303 ENOG4105C5X domain protein BAPAT_4305 ENOG4105DKQ ROK family BAPAT_4307 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BAPAT_4309 ENOG4108UTW Plays a role in the regulation of phosphate uptake BAPAT_4310 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BAPAT_4311 ENOG4105E2Z phosphate ABC transporter (Permease BAPAT_4312 ENOG4105C8U phosphate abc transporter BAPAT_4313 ENOG4105PWN phosphate abc transporter BAPAT_4314 ENOG4107RF6 penicillin-binding protein BAPAT_4316 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPAT_4320 ENOG4105N80 Ferric uptake regulator, Fur family BAPAT_4322 ENOG4105FDK ABC transporter BAPAT_4323 ENOG4108JYZ YitT family BAPAT_4324 ENOG41069ZM Protein of unknown function (DUF2624) BAPAT_4330 ENOG4105EGD dinuclear metal center protein, YbgI family BAPAT_4333 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_4334 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BAPAT_4340 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BAPAT_4341 ENOG4105KG3 cytidine deaminase BAPAT_4342 ENOG4107YR5 Diacylglycerol kinase BAPAT_4344 ENOG4105CTJ Metal Dependent Phosphohydrolase BAPAT_4345 ENOG4105C9A Phoh family BAPAT_4347 ENOG41068P3 sporulation protein YqfC BAPAT_4348 ENOG4105KTH gatB Yqey BAPAT_4350 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BAPAT_4351 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BAPAT_4355 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BAPAT_4357 ENOG4105CSA Coproporphyrinogen iii oxidase BAPAT_4358 ENOG4105KVH Transcriptional regulator BAPAT_4363 ENOG4105TQK DNA polymerase iii, delta' subunit BAPAT_4367 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BAPAT_4368 ENOG4108UK2 deaminase BAPAT_4369 ENOG4105KQC Competence protein BAPAT_4371 ENOG4105DXX methyltransferase BAPAT_4373 ENOG4108WF2 Metal Dependent Phosphohydrolase BAPAT_4375 ENOG410812S Rna-binding protein BAPAT_4377 ENOG4105CQW ribosome biogenesis GTPase YqeH BAPAT_4378 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAPAT_4381 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_4385 ENOG4108TVJ Nitroreductase BAPAT_4389 ENOG4105G6Z alkaline phosphatase BAPAT_4392 ENOG4108MUZ hydrolase BAPAT_4399 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BAPAT_4401 ENOG4105MIR Phenylalanine 4-monooxygenase BAPAT_4403 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_4411 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAPAT_4412 ENOG4108V5C ABC transporter BAPAT_4414 ENOG4108EKI Dehydrogenase BAPAT_4415 ENOG4105C28 cystathionine BAPAT_4421 ENOG4107XRG penicillin-binding protein BAPAT_4424 ENOG4105CFP Peptidase U32 BAPAT_4425 ENOG4105XYU peptidase (U32 family) BAPAT_4426 ENOG4108VQJ O-methyltransferase BAPAT_4427 ENOG4105HHA aminodeoxychorismate lyase BAPAT_4431 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BAPAT_4433 ENOG4105C02 permease BAPAT_4436 ENOG41060CR BAPAT_4437 ENOG4105C7H Helicase, RecD TraA family BAPAT_4439 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BAPAT_4440 ENOG4105C3J Cysteine desulfurase BAPAT_4442 ENOG4105D1H recombination factor protein RarA BAPAT_4443 ENOG4108VCI transcription factor, rsfa family BAPAT_4444 ENOG4105CUZ uba thif-type nad fad binding protein BAPAT_4446 ENOG4105CUT histidyl-tRNA synthetase BAPAT_4449 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BAPAT_4451 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BAPAT_4452 ENOG41076HS cation diffusion facilitator family transporter BAPAT_4453 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BAPAT_4455 ENOG4105CKP Polysaccharide Biosynthesis Protein BAPAT_4456 ENOG4108QG2 Membrane BAPAT_4458 ENOG4105VIE preprotein translocase, subunit YajC BAPAT_4461 ENOG41061AI Protein of unknown function (DUF2905) BAPAT_4464 ENOG4108HUF Transporter BAPAT_4466 ENOG4108IPJ Membrane BAPAT_4467 ENOG4108IPJ Membrane BAPAT_4468 ENOG41082BM Transcriptional regulator, arsr family BAPAT_4473 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BAPAT_4474 ENOG4108IYU L-aspartate oxidase BAPAT_4477 ENOG4108RPX mosc domain containing protein BAPAT_4478 ENOG4105CQC Prephenate dehydratase BAPAT_4483 ENOG4105EWM Histidine kinase BAPAT_4486 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BAPAT_4489 ENOG4105X36 (ribosomal) protein BAPAT_4491 ENOG4105C03 ribonuclease BAPAT_4494 ENOG4107QMS site-determining protein BAPAT_4497 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BAPAT_4498 ENOG4105DFF Rod shape-determining protein mreb BAPAT_4502 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BAPAT_4503 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BAPAT_4505 ENOG41068KH stage VI sporulation protein D BAPAT_4507 ENOG4105D52 delta-aminolevulinic acid dehydratase BAPAT_4512 ENOG4105K56 Transcriptional regulator BAPAT_4516 ENOG4108IUQ atp-dependent protease BAPAT_4521 ENOG4108QCI YvbH-like oligomerisation region BAPAT_4523 ENOG4105M59 Phosphodiesterase, mj0936 family BAPAT_4526 ENOG4108XJQ germination protein BAPAT_4528 ENOG4108PCX Major Facilitator BAPAT_4531 ENOG4105KBX Transcriptional regulator, TetR family BAPAT_4534 ENOG4105PFC Transcriptional regulator BAPAT_4537 ENOG4105DZC cytosine deaminase BAPAT_4538 ENOG4105DZC cytosine deaminase BAPAT_4539 ENOG4105DEF Extracellular solute-binding protein, family 5 BAPAT_4540 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BAPAT_4543 ENOG4108JQ7 (ABC) transporter BAPAT_4544 ENOG4108HRK Histidine kinase BAPAT_4545 ENOG4105DY9 regulatoR BAPAT_4549 ENOG4108JCI Transcriptional regulator BAPAT_4551 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BAPAT_4552 ENOG4108Z40 Transcriptional regulator BAPAT_4553 ENOG4105RHA ABC transporter, permease BAPAT_4554 ENOG4108IUX (ABC) transporter BAPAT_4555 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BAPAT_4556 ENOG4105ER2 Ompa motb domain protein BAPAT_4557 ENOG4105ER2 Ompa motb domain protein BAPAT_4558 ENOG4105E14 MotA TolQ exbB proton channel BAPAT_4559 ENOG4108VXD carboxy-peptidase BAPAT_4561 ENOG4105E33 succinate dehydrogenase BAPAT_4563 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BAPAT_4566 ENOG4105K63 Thioredoxin BAPAT_4567 ENOG4105C10 Electron transfer flavoprotein BAPAT_4568 ENOG4105BZJ Electron transfer flavoprotein BAPAT_4569 ENOG41060WC Enoyl-CoA hydratase BAPAT_4570 ENOG4107Z3H Transcriptional regulator, TetR family BAPAT_4571 ENOG4105CEY Amp-dependent synthetase and ligase BAPAT_4574 ENOG4105J76 Periplasmic binding protein BAPAT_4575 ENOG4105S6R Iron-hydroxamate transporter permease subunit BAPAT_4583 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_4586 ENOG4105DR4 Methyltransferase BAPAT_4589 ENOG4105KFN sortase, SrtB family BAPAT_4590 ENOG4105E0A ABC, transporter BAPAT_4593 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BAPAT_4595 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BAPAT_4597 ENOG4105FE9 pseudouridine synthase BAPAT_4599 ENOG4105DCG PHP domain protein BAPAT_4605 ENOG4105C5S asparaginyl-tRNA synthetase BAPAT_4606 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BAPAT_4608 ENOG4108RWN rrna methyltransferase BAPAT_4615 ENOG4105C0R drug resistance transporter emrb qaca subfamily BAPAT_4616 ENOG4105CW7 secretion protein, HlyD family BAPAT_4617 ENOG4108JGH Tetr family transcriptional regulator BAPAT_4618 ENOG4105CN9 Peptidase m42 family protein BAPAT_4622 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BAPAT_4623 ENOG4105C22 threonyL-tRNA synthetase BAPAT_4624 ENOG4108TDW sporulation protein YtxC BAPAT_4628 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAPAT_4629 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BAPAT_4630 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BAPAT_4632 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BAPAT_4633 ENOG4105C2M dna polymerase I BAPAT_4634 ENOG4105BZU Histidine kinase BAPAT_4635 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_4639 ENOG4108HMX isocitrate dehydrogenase (NADP) BAPAT_4640 ENOG4105BZN citrate synthase BAPAT_4642 ENOG4108REF Sporulation integral membrane protein ytvi BAPAT_4643 ENOG4105FS0 cytoplasmic membrane protein BAPAT_4648 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BAPAT_4649 ENOG4105C6K Malic enzyme BAPAT_4650 ENOG4105C0B DNA polymerase III (alpha subunit) BAPAT_4651 ENOG4105VV2 BAPAT_4653 ENOG4105SFS phosphoesterase RecJ domain protein BAPAT_4661 ENOG4105DC7 peptidase M24 BAPAT_4667 ENOG4105Z7P Acetyltransferase (GNAT) family BAPAT_4668 ENOG41082W1 Cupin 2, conserved barrel domain protein BAPAT_4670 ENOG4105VZ8 Transcriptional regulator BAPAT_4674 ENOG4107YZX Universal stress protein BAPAT_4682 ENOG4108JYZ YitT family BAPAT_4686 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BAPAT_4688 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BAPAT_4689 ENOG4105KBJ sporulation protein ytfj BAPAT_4692 ENOG4105EFZ amidohydrolase BAPAT_4694 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BAPAT_4700 ENOG4106KR7 LysR family Transcriptional regulator BAPAT_4702 ENOG4105U5Y Transcriptional regulator BAPAT_4703 ENOG4105U5Y Transcriptional regulator BAPAT_4705 ENOG4105C28 cystathionine BAPAT_4709 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAPAT_4711 ENOG4105EMN RNA polymerase sigma factor BAPAT_4714 ENOG4105F1V Acetoin utilization protein BAPAT_4715 ENOG4105W87 Cbs domain BAPAT_4716 ENOG4105DGU Histone deacetylase BAPAT_4718 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_4720 ENOG4107SNB ankyrin repeat protein YahD BAPAT_4721 ENOG4105EP9 oxidoreductase BAPAT_4727 ENOG4105ETE Transcriptional regulator (LacI family BAPAT_4731 ENOG4105C88 aminopeptidase BAPAT_4739 ENOG4108VDD TRNA binding domain protein BAPAT_4745 ENOG4105C8F Beta-lactamase domain protein BAPAT_4748 ENOG4108V15 phosphotransferase enzyme family BAPAT_4749 ENOG4108IUM Glycogen debranching enzyme BAPAT_4751 ENOG4107QSE Dipeptidase BAPAT_4752 ENOG4105YW5 deoR family transcriptional regulator BAPAT_4755 ENOG4105CBX hi0933 family BAPAT_4763 ENOG4108VJ1 Transcriptional regulator (CarD family BAPAT_4764 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BAPAT_4765 ENOG4105CSC Glucose uptake protein BAPAT_4768 ENOG4108ZAF Molybdopterin BAPAT_4769 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BAPAT_4770 ENOG4105CVM Molybdenum cofactor synthesis domain protein BAPAT_4772 ENOG4105D06 uba thif-type nad fad binding protein BAPAT_4773 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BAPAT_4778 ENOG41085GJ domain protein BAPAT_4780 ENOG4105DWV Homoserine O-trans-acetylase BAPAT_4784 ENOG4108B31 Spore germination protein BAPAT_4791 ENOG410605W Major Facilitator BAPAT_4792 ENOG4107S91 Sodium hydrogen exchanger BAPAT_4793 ENOG4105NCW Trka-c domain protein BAPAT_4796 ENOG4105C19 ABC transporter BAPAT_4800 ENOG4105N5T Radical SAM Protein BAPAT_4802 ENOG4105DA5 (ABC) transporter BAPAT_4809 ENOG4105E8V Alpha Beta Hydrolase Fold protein BAPAT_4810 ENOG4108Z0R Transferase BAPAT_4811 ENOG4105YVM Phosphoesterase, PA-phosphatase related BAPAT_4812 ENOG4105BZF Glycosyl transferase (Group 1 BAPAT_4814 ENOG4108RIR Molybdenum cofactor biosynthesis protein BAPAT_4822 ENOG4105EGD dinuclear metal center protein, YbgI family BAPAT_4823 ENOG4105BZU Histidine kinase BAPAT_4824 ENOG4105BZU Histidine kinase BAPAT_4825 ENOG4107S9D Alpha beta hydrolase BAPAT_4826 ENOG4107T7U Sulfatase BAPAT_4830 ENOG4105D2X ABC transporter substrate-binding protein BAPAT_4832 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BAPAT_4835 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BAPAT_4843 ENOG4108V2W Carbonate dehydratase BAPAT_4844 ENOG4105C4M (Ubiquinol oxidase) subunit I BAPAT_4845 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BAPAT_4854 ENOG41087YS Phage shock protein A BAPAT_4860 ENOG4105BZU Histidine kinase BAPAT_4861 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_4866 ENOG4108UGV hypoxanthine phosphoribosyltransferase BAPAT_4867 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BAPAT_4873 ENOG4107ZTW SNARE associated Golgi BAPAT_4876 ENOG4105C19 ABC transporter BAPAT_4877 ENOG41086D8 Transcriptional regulator BAPAT_4887 ENOG4105C6Z Gluconate BAPAT_4888 ENOG4105FDP GntR family transcriptional regulator BAPAT_4892 ENOG41069H0 dihydroorotase EC 3.5.2.3 BAPAT_4899 ENOG4105DTQ mandelate racemase muconate lactonizing BAPAT_4901 ENOG4108IPT Naphthoate synthase BAPAT_4902 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BAPAT_4903 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BAPAT_4904 ENOG4105E4F Isochorismate synthase BAPAT_4905 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BAPAT_4907 ENOG4105VEQ Cold shock protein BAPAT_4911 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BAPAT_4913 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BAPAT_4915 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPAT_4917 ENOG4105KT7 mgtC SapB transporter BAPAT_4918 ENOG4107PBV potassium channel BAPAT_4920 ENOG4107QYV phosphohexose isomerase BAPAT_4921 ENOG4105WG9 Conserved Protein BAPAT_4923 ENOG4105CHM Aminotransferase BAPAT_4924 ENOG4108ZB6 transcriptional regulator AsnC family BAPAT_4925 ENOG4105C5I Dehydrogenase BAPAT_4926 ENOG4108MUZ hydrolase BAPAT_4928 ENOG4105C87 Aminotransferase class I and II BAPAT_4931 ENOG4105Y38 Kinase-associated protein B BAPAT_4933 ENOG4107R3E Citrate transporter BAPAT_4937 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BAPAT_4938 ENOG4105KA0 thioesterase Superfamily protein BAPAT_4942 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAPAT_4946 ENOG41069ER domain protein BAPAT_4949 ENOG4105CEP NADH dehydrogenase BAPAT_4955 ENOG4105EWC Purine nucleoside phosphorylase BAPAT_4959 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BAPAT_4964 ENOG4108JJA ABC, transporter BAPAT_4965 ENOG4105C4B ABC transporter, permease BAPAT_4966 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BAPAT_4975 ENOG41083MR nifu domain-containing protein BAPAT_4978 ENOG4108W5N phosphatidylglycerophosphatase a BAPAT_4980 ENOG4105DYS nad(p)h dehydrogenase (quinone) BAPAT_4981 ENOG4105D4U had-superfamily hydrolase, subfamily iia BAPAT_4984 ENOG4105CBT Fructose-1,6-bisphosphatase BAPAT_4987 ENOG4105MMD transcriptional regulator BAPAT_4988 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BAPAT_4989 ENOG4107TXC Transcriptional regulator BAPAT_4990 ENOG41090T1 Membrane BAPAT_4995 ENOG4105FAA peptidase M23 BAPAT_4997 ENOG4105KZD Domain of unknown function (DUF1805) BAPAT_4998 ENOG4107R8B 5'-nucleotidase BAPAT_5002 ENOG4105DIW FeS assembly protein SUFB BAPAT_5003 ENOG4108UNV SUF system FeS assembly protein, NifU family BAPAT_5004 ENOG4105C9B Cysteine desulfurase BAPAT_5005 ENOG4105JRK feS assembly protein SufD BAPAT_5006 ENOG4105C3K feS assembly ATPase SufC BAPAT_5007 ENOG4105D01 (LipO)protein BAPAT_5008 ENOG4105D01 (LipO)protein BAPAT_5009 ENOG4108UMI ABC transporter, permease BAPAT_5016 ENOG41080E8 Transcriptional regulator, Spx MgsR family BAPAT_5024 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BAPAT_5029 ENOG4108W8B Beta-lactamase domain protein BAPAT_5030 ENOG4105C1G acyl-Coa dehydrogenase BAPAT_5032 ENOG4105CHU acetyl-coa acetyltransferase BAPAT_5035 ENOG4105DZ1 carboxypeptidase BAPAT_5039 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BAPAT_5043 ENOG4108SUT Major Facilitator Superfamily BAPAT_5044 ENOG4107R7I amino acid BAPAT_5046 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAPAT_5048 ENOG4107AYK membrAne BAPAT_5055 ENOG4107ZTW SNARE associated Golgi BAPAT_5057 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BAPAT_5058 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_5059 ENOG4105BZU Histidine kinase BAPAT_5061 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BAPAT_5064 ENOG4105VG1 fes assembly suf system protein BAPAT_5065 ENOG4105D4Y metalloprotease BAPAT_5069 ENOG4107S91 Sodium hydrogen exchanger BAPAT_5070 ENOG4105NCW Trka-c domain protein BAPAT_5072 ENOG4108RMU ferritin dps family protein BAPAT_5076 ENOG4108URH decarboxylase BAPAT_5081 ENOG4105D9N nucleoside BAPAT_5082 ENOG4105D9N nucleoside BAPAT_5085 ENOG4108RYK Nad-dependent epimerase dehydratase BAPAT_5090 ENOG4105CV8 reductase BAPAT_5091 ENOG4105F27 Major Facilitator BAPAT_5092 ENOG4105KVH Transcriptional regulator BAPAT_5095 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BAPAT_5096 ENOG4105D4A Cell wall formation (By similarity) BAPAT_5098 ENOG4105C8Q Methyl-accepting chemotaxis BAPAT_5100 ENOG4105WMR Protein CrcB homolog BAPAT_5101 ENOG4105WMR Protein CrcB homolog BAPAT_5104 ENOG4108MK9 spermidine N(1)-acetyltransferase BAPAT_5105 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BAPAT_5108 ENOG4108IPW abc transporter atp-binding protein BAPAT_5109 ENOG4105CM4 permease protein BAPAT_5115 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BAPAT_5117 ENOG4105XZU Preprotein translocase, subunit SecG BAPAT_5118 ENOG41067MG lrgb family BAPAT_5138 ENOG4105EFC phage portal protein HK97 family BAPAT_5142 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPAT_5144 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BAPAT_5145 ENOG4105CP7 Triose-phosphate isomerase BAPAT_5150 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_5153 ENOG41090VF Stage v sporulation protein ac BAPAT_5154 ENOG4105CZ3 stage V sporulation protein ad BAPAT_5157 ENOG4105H67 Protein of unknown function (DUF421) BAPAT_5158 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BAPAT_5159 ENOG4105KRI phosphocarrier protein (HPr BAPAT_5161 ENOG4105CHW UPF0052 protein BAPAT_5163 ENOG4108Z4K mutator MutT protein BAPAT_5165 ENOG4105C3M thioredoxin reductase BAPAT_5167 ENOG4108S4C acetyltransferase BAPAT_5171 ENOG41086DT Membrane protein of unknown function BAPAT_5173 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BAPAT_5174 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BAPAT_5175 ENOG4105D7V transposase BAPAT_5178 ENOG4107TXC Transcriptional regulator BAPAT_5184 ENOG4105DUM transcriptional regulator, lysR family BAPAT_5186 ENOG4108WS4 fmn reductase BAPAT_5189 ENOG4105BZ1 (ABC) transporter BAPAT_5191 ENOG4105CN1 protease BAPAT_5192 ENOG4105CRP Part of the ABC transporter FtsEX involved in BAPAT_5193 ENOG4105CAK Cell division ATP-binding protein ftsE BAPAT_5198 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BAPAT_5199 ENOG4105MS2 ribosomal subunit Interface protein BAPAT_5201 ENOG4105VEQ Cold shock protein BAPAT_5202 ENOG41081UC Inherit from COG: Competence protein BAPAT_5206 ENOG4105KVH Transcriptional regulator BAPAT_5208 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BAPAT_5209 ENOG4108KGH TRANSCRIPTIONal BAPAT_5210 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAPAT_5211 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAPAT_5212 ENOG4105ESV Glycosyl transferase, family 4 BAPAT_5214 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BAPAT_5217 ENOG410901P UPF0249 protein BAPAT_5218 ENOG4105F8D glycoside hydrolase family 4 BAPAT_5219 ENOG4105VCP PTS System BAPAT_5220 ENOG4105CK1 PTS System BAPAT_5222 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BAPAT_5223 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BAPAT_5224 ENOG4105VCP PTS System BAPAT_5226 ENOG4105VZJ PTS System BAPAT_5229 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BAPAT_5230 ENOG4105ECB domain protein BAPAT_5231 ENOG4107RSM transcriptional regulator BAPAT_5239 ENOG4105DAA L-lactate BAPAT_5241 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BAPAT_5243 ENOG4105E0M Sulfatase BAPAT_5250 ENOG4107R8N Glycosyl transferase, family 2 BAPAT_5253 ENOG4105C94 Transporter BAPAT_5254 ENOG41069ER domain protein BAPAT_5259 ENOG4105KBK Zinc finger, swim domain protein BAPAT_5260 ENOG4105C0D helicase BAPAT_5266 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BAPAT_5268 ENOG4107RBB ABC transporter, permease BAPAT_5269 ENOG4105C19 ABC transporter BAPAT_5272 ENOG4105CXY transporter BAPAT_5275 ENOG4105BZU Histidine kinase BAPAT_5276 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BAPAT_5277 ENOG4105CMR udp-glucose 4-epimerase BAPAT_5280 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BAPAT_5281 ENOG4105EY8 ABC transporter BAPAT_5292 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BAPAT_5295 ENOG4105FRN stage II sporulation protein BAPAT_5298 ENOG4105DY9 regulatoR BAPAT_5299 ENOG4108IUW ABC transporter BAPAT_5303 ENOG4106778 Protein of unknown function (DUF1146) BAPAT_5304 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAPAT_5305 ENOG4105C8S subunit m BAPAT_5306 ENOG4105D65 subunit l BAPAT_5311 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BAPAT_5312 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAPAT_5314 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BAPAT_5315 ENOG4105BZU Histidine kinase BAPAT_5325 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BAPAT_5326 ENOG41062M3 atp synthase BAPAT_5332 ENOG4108YZG isomerase BAPAT_5333 ENOG4107WAU Protein tyrosine phosphatase BAPAT_5335 ENOG4108VGI doxx family BAPAT_5336 ENOG4107XC4 flavin reductase domain protein, FMN-binding BAPAT_5339 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BAPAT_5341 ENOG4108ZXQ stage ii sporulation protein r BAPAT_5342 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BAPAT_5343 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BAPAT_5346 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BAPAT_5347 ENOG4105CBT Fructose-1,6-bisphosphatase BAPAT_5348 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BAPAT_5355 ENOG4105C1G acyl-Coa dehydrogenase BAPAT_5356 ENOG4105C1G acyl-Coa dehydrogenase BAPAT_5357 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BAPAT_5359 ENOG4105DF6 Fe-S oxidoreductase BAPAT_5362 ENOG4105BZU Histidine kinase BAPAT_5367 ENOG4105BZU Histidine kinase BAPAT_5368 ENOG4105KCT ABC transporter BAPAT_5369 ENOG4108M15 ABC transporter BAPAT_5370 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BAPAT_5374 ENOG4105IIU Aminopeptidase BAPAT_5378 ENOG4105EMN RNA polymerase sigma factor BAPAT_5380 ENOG410684U Domain of unknown function (DUF1934) BAPAT_5385 ENOG4105CYW agmatinase BAPAT_5387 ENOG4105DXB Major Facilitator superfamily BAPAT_5388 ENOG4107SWG transcriptional regulator MERR family BAPAT_5389 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BAPAT_5390 ENOG4105BZ4 penicillin-binding protein BAPAT_5391 ENOG4108XFG YwhD family BAPAT_5392 ENOG4108Z4T Peptidase M50 BAPAT_5393 ENOG41069HH 4-oxalocrotonate tautomerase BAPAT_5394 ENOG4105DCI Phosphohydrolase BAPAT_5395 ENOG4108MES Periplasmic binding protein BAPAT_5396 ENOG4105E0A ABC, transporter BAPAT_5397 ENOG4105EHG Permease protein BAPAT_5398 ENOG4105DQ5 transport system permease protein BAPAT_5400 ENOG4108VCI transcription factor, rsfa family BAPAT_5403 ENOG4108IJ2 phosphate acetyltransferase BAPAT_5406 ENOG4108VKI Cell wall hydrolase BAPAT_5410 ENOG4107SVH Potassium channel protein BAPAT_5412 ENOG410667J hydrolase BAPAT_5413 ENOG4105VCH membrane BAPAT_5415 ENOG4108TU7 Inherit from COG: (ABC) transporter BAPAT_5416 ENOG4105CJ1 ABC, transporter BAPAT_5417 ENOG41090WU lipolytic protein G-D-S-L family BAPAT_5420 ENOG4105D6E homoserine dehydrogenase BAPAT_5425 ENOG4108Y4K DNA-binding transcriptional activator BAPAT_5427 ENOG4105WH1 Two component transcriptional regulator luxr family BAPAT_5428 ENOG4105BZU Histidine kinase BAPAT_5429 ENOG4105BZU Histidine kinase BAPAT_5430 ENOG4105DWF phosphomethylpyrimidine kinase BAPAT_5431 ENOG4105BZU Histidine kinase BAPAT_5432 ENOG4105VCD cytoplasmic protein BAPAT_5433 ENOG4105D22 carbon starvation protein BAPAT_5434 ENOG4105DY9 regulatoR BAPAT_5435 ENOG41079KZ Major Facilitator Superfamily BAPAT_5440 ENOG4105EN6 Membrane BAPAT_5441 ENOG4106YBV Methyl-accepting chemotaxis BAPAT_5442 ENOG4106YBV Methyl-accepting chemotaxis BAPAT_5444 ENOG4108S4H thioesterase Superfamily protein BAPAT_5446 ENOG4105JEU Glycosyl transferase, family 2 BAPAT_5447 ENOG4105C5H ABC transporter BAPAT_5451 ENOG4105CKK Glycosyl transferase, family 2 BAPAT_5452 ENOG41067SE Tetr family transcriptional regulator BAPAT_5454 ENOG4105E0X reductase BAPAT_5455 ENOG4106F5Q Membrane BAPAT_5458 ENOG4105DY9 regulatoR BAPAT_5459 ENOG4108HRK Histidine kinase BAPAT_5460 ENOG4107RGD Major Facilitator superfamily BAPAT_5463 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BAPAT_5465 ENOG4105IW1 AmiS UreI transporter BAPAT_5467 ENOG4105CMR udp-glucose 4-epimerase BAPAT_5468 ENOG4108UT2 hemolysin iii BAPAT_5470 ENOG4105C1J atp-dependent rna helicase BAPAT_5473 ENOG4105DPN Oligoendopeptidase f BAPAT_5477 ENOG4105C0H protease BAPAT_5478 ENOG4105Q2H domain protein BAPAT_5481 ENOG4105BZU Histidine kinase BAPAT_5482 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BAPAT_5484 ENOG4105CDU Replicative dna helicase BAPAT_5486 ENOG4105BZR domain protein BAPAT_5487 ENOG4108XMW Membrane BAPAT_5489 ENOG4108UUM single-stranded DNA-binding protein BAPAT_5491 ENOG4105C3G gtp-binding protein BAPAT_5492 ENOG4105VDK protein, conserved in bacteria BAPAT_5493 ENOG4105D8X mechanosensitive ion channel BAPAT_5494 ENOG4108ZDA Sporulation protein YyaC BAPAT_5495 ENOG4105FA0 parb-like partition protein BAPAT_5496 ENOG4107QJE Chromosome Partitioning Protein BAPAT_5500 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BAPAT_5502 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BAPAT_pXO10011 ENOG4105EKQ RNA-directed DNA polymerase BAPAT_pXO10033 ENOG4105EKQ RNA-directed DNA polymerase BAPAT_pXO10046 ENOG4106JUT Streptomycin 3''-adenylyltransferase BAPAT_pXO10061 ENOG4105CNU cell division protein FtsK BAPAT_pXO10112 ENOG4105DHF Membrane BAPAT_pXO10118 ENOG4106AKK s-layer domain-containing protein BAPAT_pXO10119 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BAPAT_pXO10123 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BAPAT_pXO10124 ENOG4105C6Y Udp-glucose 6-dehydrogenase BAPAT_pXO10127 ENOG4105DQ6 Transposase BAPAT_pXO10138 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BAPAT_pXO10173 ENOG4105KRN Transcriptional regulator, abrb family BAPAT_pXO10176 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BAPAT_pXO10184 ENOG4108IBT Inherit from COG: transposase BAPAT_pXO10186 ENOG4105DQ6 Transposase BAPAT_pXO10187 ENOG4105DQ6 Transposase BAPAT_pXO10190 ENOG4105DQ6 Transposase BAPAT_pXO10191 ENOG4105DQ6 Transposase BAPAT_pXO10195 ENOG4108MEK Metal-binding protein YodA BAPAT_pXO10198 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BAPAT_pXO10205 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BAPAT_pXO20045 ENOG4107QJE Chromosome Partitioning Protein BAPAT_pXO20052 ENOG4105DQ6 Transposase BAPAT_pXO20059 ENOG4105EWC Purine nucleoside phosphorylase BAPAT_pXO20078 ENOG4105C3F Signal peptidase i BAPAT_pXO20084 ENOG4105N14 lysine exporter protein LysE YggA BAPAT_pXO20091 ENOG4108J59 Extracellular solute-binding protein, family 5 BAPAT_pXO20095 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BAPAT_pXO20105 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPAT_pXO20106 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BAPAT_tRNALeu6 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation