locus-tag	class	description
AW20_1	COG1115	amino acid carrier protein
AW20_1002	COG1131	(ABC) transporter
AW20_1009	COG2733	membrane
AW20_1016	COG0785	Cytochrome C biogenesis protein
AW20_102	COG0076	glutamate decarboxylase activity
AW20_1020	COG3340	Belongs to the peptidase S51 family
AW20_1021	COG0534	Mate efflux family protein
AW20_1022	COG0534	Mate efflux family protein
AW20_1026	COG0114	fumarate hydratase activity
AW20_1027	COG1757	Na H antiporter
AW20_1028	COG0438	transferase activity, transferring glycosyl groups
AW20_1028	COG1216	Glycosyl transferase, family 2
AW20_1030	COG0701	Predicted permease
AW20_1031	COG0523	cobalamin synthesis protein
AW20_1032	COG0697	spore germination
AW20_1033	COG1802	Transcriptional regulator
AW20_1039	COG0367	asparagine synthase
AW20_1046	COG0406	alpha-ribazole phosphatase activity
AW20_1048	COG1686	Belongs to the peptidase S11 family
AW20_1053	COG1234	tRNA 3'-trailer cleavage
AW20_1055	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW20_1056	COG3842	ATPase activity
AW20_1057	COG0583	DNA-binding transcription factor activity
AW20_1062	COG2329	Antibiotic biosynthesis monooxygenase
AW20_1066	COG1309	transcriptional regulator
AW20_107	COG1011	Hydrolase
AW20_1071	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_1072	COG4786	Flagellar basal body rod
AW20_1075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW20_1076	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW20_1078	COG1987	bacterial-type flagellum assembly
AW20_1079	COG1338	Plays a role in the flagellum-specific transport system
AW20_1081	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_1081	COG1776	CheC inhibitor of MCP methylation
AW20_1083	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_1084	COG0741	lytic transglycosylase activity
AW20_1085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW20_1090	COG0457	Tetratricopeptide repeat
AW20_1090	COG0463	Glycosyl transferase, family 2
AW20_1096	COG0463	Glycosyl transferase, family 2
AW20_1098	COG0784	Response regulator, receiver
AW20_1098	COG0835	chemotaxis
AW20_1099	COG0784	Response regulator, receiver
AW20_1099	COG0835	chemotaxis
AW20_1108	COG1157	protein secretion by the type III secretion system
AW20_1110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_1112	COG1766	The M ring may be actively involved in energy transduction
AW20_1114	COG1558	bacterial-type flagellum-dependent cell motility
AW20_1115	COG1815	bacterial-type flagellum-dependent cell motility
AW20_112	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_1120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW20_1121	COG1256	bacterial-type flagellum assembly
AW20_1125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW20_1128	COG1776	CheC inhibitor of MCP methylation
AW20_1128	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_1129	COG0643	Histidine kinase
AW20_1129	COG2198	Histidine kinase
AW20_1130	COG2198	Histidine kinase
AW20_1130	COG0643	Histidine kinase
AW20_1131	COG2201	protein-glutamate methylesterase activity
AW20_1132	COG1360	Flagellar Motor Protein
AW20_1133	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW20_1135	COG1923	regulation of RNA biosynthetic process
AW20_1146	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW20_1147	COG2323	membrane
AW20_1149	COG4978	Transcriptional regulator
AW20_1149	COG0789	Transcriptional regulator
AW20_1150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_1151	COG0475	glutathione-regulated potassium exporter activity
AW20_1153	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_1154	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_1155	COG3162	membrane
AW20_1158	COG1280	lysine exporter protein (LysE YggA)
AW20_1166	COG0328	RNA-DNA hybrid ribonuclease activity
AW20_1170	COG0454	-acetyltransferase
AW20_1173	COG0438	transferase activity, transferring glycosyl groups
AW20_1174	COG1215	transferase activity, transferring glycosyl groups
AW20_1177	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW20_1183	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_1186	COG0754	glutathionylspermidine amidase activity
AW20_1191	COG0456	acetyltransferase
AW20_1193	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_1195	COG2311	Membrane
AW20_1196	COG2233	PERMEase
AW20_1198	COG0024	Methionine aminopeptidase
AW20_1199	COG3173	Aminoglycoside phosphotransferase
AW20_12	COG0514	ATP-dependent DNA helicase (RecQ)
AW20_120	COG0322	excinuclease ABC activity
AW20_1201	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW20_1202	COG1199	ATP-dependent helicase activity
AW20_1204	COG0116	Belongs to the methyltransferase superfamily
AW20_1215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_1215	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW20_1217	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW20_1218	COG3935	DnaD domain protein
AW20_1222	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW20_1222	COG1199	ATP-dependent helicase activity
AW20_1229	COG0438	transferase activity, transferring glycosyl groups
AW20_1230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_1233	COG1694	Mazg nucleotide pyrophosphohydrolase
AW20_1234	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_1236	COG2738	Putative neutral zinc metallopeptidase
AW20_1239	COG4347	Protein of unknown function (DUF1405)
AW20_124	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW20_1241	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW20_1245	COG0457	Tetratricopeptide repeat
AW20_1246	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW20_1250	COG0142	geranyltranstransferase activity
AW20_1252	COG0142	geranyltranstransferase activity
AW20_1255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_1269	COG0252	asparaginase activity
AW20_1270	COG0492	ferredoxin-NADP+ reductase activity
AW20_1274	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW20_1275	COG4862	establishment of competence for transformation
AW20_1277	COG1408	metallophosphoesterase
AW20_1279	COG1266	CAAX protease self-immunity
AW20_1280	COG0514	ATP-dependent DNA helicase (RecQ)
AW20_1281	COG4955	Helix-turn-helix domain
AW20_1282	COG1141	Ferredoxin
AW20_1283	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW20_1286	COG2096	Adenosyltransferase
AW20_1287	COG5002	protein histidine kinase activity
AW20_1288	COG0745	RESPONSE REGULATOR receiver
AW20_1289	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW20_129	COG4667	esterase of the alpha-beta hydrolase superfamily
AW20_1290	COG1333	cytochrome c biogenesis protein
AW20_1292	COG1187	pseudouridine synthase activity
AW20_1293	COG0700	Nucleoside recognition
AW20_1294	COG2715	membrane protein required for spore maturation
AW20_1295	COG1686	Belongs to the peptidase S11 family
AW20_1296	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_1299	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW20_1299	COG0392	lysyltransferase activity
AW20_13	COG2105	PFAM AIG2 family protein
AW20_1303	COG5002	protein histidine kinase activity
AW20_1304	COG0582	viral genome integration into host DNA
AW20_1306	COG1801	Protein of unknown function DUF72
AW20_1307	COG3852	Histidine kinase
AW20_1310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_1311	COG1392	Phosphate transport regulator
AW20_1312	COG0306	phosphate transporter
AW20_1313	COG0730	response to heat
AW20_1316	COG1017	nitric oxide dioxygenase activity
AW20_1316	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW20_1321	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW20_1323	COG1114	Component of the transport system for branched-chain amino acids
AW20_1325	COG2197	response regulator
AW20_1326	COG4585	Histidine kinase
AW20_1327	COG4758	membrane
AW20_1330	COG1757	Na H antiporter
AW20_1334	COG0733	neurotransmitter:sodium symporter activity
AW20_1335	COG1648	precorrin-2 dehydrogenase activity
AW20_1339	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW20_1340	COG0529	Catalyzes the synthesis of activated sulfate
AW20_1344	COG0019	diaminopimelate decarboxylase activity
AW20_1346	COG1368	sulfuric ester hydrolase activity
AW20_1347	COG1183	phosphatidylcholine synthase activity
AW20_135	COG3878	Protein conserved in bacteria
AW20_1350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW20_1357	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW20_1362	COG0473	3-isopropylmalate dehydrogenase activity
AW20_1364	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW20_1365	COG0440	acetolactate synthase activity
AW20_1366	COG0028	Belongs to the TPP enzyme family
AW20_1367	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_1372	COG3874	Sporulation protein YtfJ
AW20_1373	COG4709	membrane
AW20_1374	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_1375	COG1301	dicarboxylic acid transport
AW20_1377	COG1846	Transcriptional regulator
AW20_1380	COG1968	undecaprenyl-diphosphatase activity
AW20_1381	COG0534	Mate efflux family protein
AW20_1385	COG3173	Aminoglycoside phosphotransferase
AW20_1388	COG0716	FMN binding
AW20_1393	COG1696	Membrane protein involved in D-alanine export
AW20_1395	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW20_1396	COG2070	2-Nitropropane dioxygenase
AW20_1397	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_1399	COG1335	isochorismatase
AW20_1401	COG1522	sequence-specific DNA binding
AW20_1404	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_1405	COG1131	(ABC) transporter
AW20_1407	COG1131	(ABC) transporter
AW20_1408	COG1725	Transcriptional regulator
AW20_1409	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW20_1410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW20_1412	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW20_1413	COG1780	Probably involved in ribonucleotide reductase function
AW20_1419	COG4873	Protein conserved in bacteria
AW20_142	COG1051	belongs to the nudix hydrolase family
AW20_1422	COG0720	synthase
AW20_1424	COG5002	protein histidine kinase activity
AW20_1426	COG2318	DinB family
AW20_1428	COG1846	Transcriptional regulator
AW20_1429	COG3852	Histidine kinase
AW20_143	COG0592	DNA-directed DNA polymerase activity
AW20_1431	COG2861	carbohydrate metabolic process
AW20_1434	COG0235	Class ii aldolase
AW20_1439	COG1349	DNA-binding transcription factor activity
AW20_144	COG2816	NAD+ diphosphatase activity
AW20_1445	COG3842	ATPase activity
AW20_1446	COG3842	ATPase activity
AW20_1448	COG1840	ABC-type Fe3 transport system, periplasmic component
AW20_1451	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_1453	COG3243	poly(R)-hydroxyalkanoic acid synthase
AW20_1454	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_1458	COG2030	dehydratase
AW20_146	COG2223	nitrite transmembrane transporter activity
AW20_1460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_1461	COG0861	Integral membrane protein TerC family
AW20_1462	COG2116	formate transmembrane transporter activity
AW20_1464	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW20_1468	COG2186	Transcriptional regulator
AW20_1469	COG5002	protein histidine kinase activity
AW20_1470	COG0745	RESPONSE REGULATOR receiver
AW20_1472	COG3835	regulator
AW20_1473	COG0277	FAD linked oxidase domain protein
AW20_1474	COG0247	lactate metabolic process
AW20_1475	COG2340	Cysteine-rich secretory protein family
AW20_1477	COG0564	pseudouridine synthase activity
AW20_1479	COG2409	Drug exporters of the RND superfamily
AW20_1481	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW20_1482	COG1177	transmembrane transport
AW20_1483	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW20_1484	COG3842	ATPase activity
AW20_1485	COG1012	belongs to the aldehyde dehydrogenase family
AW20_1491	COG0681	Belongs to the peptidase S26 family
AW20_1492	COG1686	Belongs to the peptidase S11 family
AW20_1494	COG2226	methyltransferase
AW20_1505	COG1476	TRANSCRIPTIONal
AW20_1507	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_1517	COG5634	Uncharacterized conserved protein (DUF2278)
AW20_1518	COG1620	l-lactate permease
AW20_1525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW20_1525	COG0512	Glutamine amidotransferase of anthranilate synthase
AW20_1527	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_1528	COG5492	domain, Protein
AW20_153	COG0697	spore germination
AW20_1531	COG2382	esterase
AW20_1533	COG2153	protein acetylation
AW20_154	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_1541	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW20_1544	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW20_1548	COG0457	Tetratricopeptide repeat
AW20_1548	COG0463	Glycosyl transferase, family 2
AW20_155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_1553	COG0463	Glycosyl transferase, family 2
AW20_1553	COG1216	Glycosyl transferase, family 2
AW20_1554	COG0772	Belongs to the SEDS family
AW20_1555	COG0772	Belongs to the SEDS family
AW20_1559	COG0564	pseudouridine synthase activity
AW20_1561	COG2357	RelA SpoT domain protein
AW20_1563	COG4116	CYTH
AW20_1564	COG2346	COG2346, Truncated hemoglobins
AW20_1567	COG1164	Oligoendopeptidase f
AW20_1569	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_1570	COG4862	establishment of competence for transformation
AW20_1571	COG0861	Integral membrane protein TerC family
AW20_1574	COG4166	transmembrane transport
AW20_1575	COG0534	Mate efflux family protein
AW20_1576	COG4608	Belongs to the ABC transporter superfamily
AW20_1577	COG0444	Belongs to the ABC transporter superfamily
AW20_1578	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_1579	COG0601	transmembrane transport
AW20_158	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_1580	COG4166	transmembrane transport
AW20_1582	COG0180	Tryptophanyl-tRNA synthetase
AW20_1584	COG5504	Zn-dependent protease
AW20_1585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW20_1586	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_1589	COG2267	carboxylic ester hydrolase activity
AW20_1591	COG0542	response to heat
AW20_1593	COG0561	phosphatase activity
AW20_1596	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_1598	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_16	COG3973	AAA domain
AW20_1600	COG2996	Protein conserved in bacteria
AW20_1604	COG0004	ammonium transporteR
AW20_1605	COG0753	catalase activity
AW20_1607	COG0367	asparagine synthase
AW20_1612	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW20_162	COG2814	Major facilitator Superfamily
AW20_1620	COG1074	ATP-dependent DNA helicase activity
AW20_1621	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW20_1623	COG0398	Pfam SNARE associated Golgi protein
AW20_1624	COG4903	ComK protein
AW20_1629	COG2224	Isocitrate lyase
AW20_1630	COG2224	Isocitrate lyase
AW20_1631	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW20_1635	COG0697	spore germination
AW20_1636	COG0840	transmembrane signaling receptor activity
AW20_1637	COG0501	Belongs to the peptidase M48B family
AW20_1642	COG0745	RESPONSE REGULATOR receiver
AW20_1643	COG2205	protein histidine kinase activity
AW20_1646	COG2207	Transcriptional regulator
AW20_1646	COG3708	Transcriptional regulator
AW20_1647	COG1595	DNA-templated transcription, initiation
AW20_1649	COG1078	dGTPase activity
AW20_1650	COG1408	metallophosphoesterase
AW20_1657	COG3209	COG3209 Rhs family protein
AW20_1663	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_1665	COG0095	Lipoate-protein ligase
AW20_1666	COG1234	tRNA 3'-trailer cleavage
AW20_1668	COG1609	Transcriptional regulator
AW20_1669	COG1609	Transcriptional regulator
AW20_167	COG0693	protein deglycase activity
AW20_1674	COG1511	domain protein
AW20_1675	COG1309	transcriptional regulator
AW20_1684	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW20_1685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_1686	COG2329	Antibiotic biosynthesis monooxygenase
AW20_1687	COG3428	Bacterial PH domain
AW20_1688	COG3402	PFAM membrane-flanked domain
AW20_1697	COG3428	Bacterial PH domain
AW20_1699	COG3402	PFAM membrane-flanked domain
AW20_1701	COG1309	transcriptional regulator
AW20_1704	COG4473	ABC transporter
AW20_1705	COG1131	(ABC) transporter
AW20_1706	COG0537	adenosine 5'-monophosphoramidase activity
AW20_1707	COG4980	gas vesicle protein
AW20_1711	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_1712	COG3973	AAA domain
AW20_1714	COG0477	Major facilitator Superfamily
AW20_1715	COG0477	Major facilitator Superfamily
AW20_1723	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW20_1725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW20_1726	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW20_173	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_1731	COG2267	carboxylic ester hydrolase activity
AW20_1733	COG0457	Tetratricopeptide repeat
AW20_1734	COG0346	lactoylglutathione lyase activity
AW20_1735	COG0346	lactoylglutathione lyase activity
AW20_1736	COG2814	Major facilitator Superfamily
AW20_1737	COG1309	transcriptional regulator
AW20_1741	COG4717	serine-type aminopeptidase activity
AW20_1742	COG0420	3'-5' exonuclease activity
AW20_1753	COG2205	protein histidine kinase activity
AW20_1753	COG2198	Histidine kinase
AW20_1753	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_1753	COG0784	Response regulator, receiver
AW20_1754	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW20_1755	COG2208	phosphoserine phosphatase activity
AW20_1757	COG1191	sigma factor activity
AW20_176	COG0604	alcohol dehydrogenase
AW20_1762	COG3237	CsbD-like
AW20_1772	COG3437	response regulator, receiver
AW20_1772	COG2770	Histidine kinase
AW20_1777	COG1959	2 iron, 2 sulfur cluster binding
AW20_1778	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_1779	COG2376	Dihydroxyacetone kinase
AW20_1781	COG2376	Dihydroxyacetone kinase
AW20_1785	COG1183	phosphatidylcholine synthase activity
AW20_1789	COG1309	transcriptional regulator
AW20_179	COG2205	protein histidine kinase activity
AW20_1790	COG3320	Male sterility
AW20_1790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW20_1800	COG0477	Major facilitator Superfamily
AW20_1808	COG0305	Participates in initiation and elongation during chromosome replication
AW20_1811	COG0789	Transcriptional regulator
AW20_1811	COG4978	Transcriptional regulator
AW20_1816	COG3181	Tripartite tricarboxylate transporter family receptor
AW20_1817	COG4565	transcriptional regulatory protein
AW20_1818	COG3290	protein histidine kinase activity
AW20_1819	COG0477	Major facilitator Superfamily
AW20_182	COG1122	ATPase activity
AW20_1825	COG4608	Belongs to the ABC transporter superfamily
AW20_1826	COG0444	Belongs to the ABC transporter superfamily
AW20_1827	COG0444	Belongs to the ABC transporter superfamily
AW20_1828	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_1829	COG0601	transmembrane transport
AW20_1836	COG3938	Belongs to the proline racemase family
AW20_184	COG1794	racemase activity, acting on amino acids and derivatives
AW20_1840	COG1363	Peptidase, m42
AW20_1843	COG1024	Enoyl-CoA hydratase
AW20_1846	COG1696	Membrane protein involved in D-alanine export
AW20_1849	COG4196	transglutaminase domain protein
AW20_185	COG1819	glycosyl
AW20_1850	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_1852	COG2244	polysaccharide biosynthetic process
AW20_1853	COG0653	protein targeting
AW20_1857	COG0659	secondary active sulfate transmembrane transporter activity
AW20_1860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW20_1862	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_1862	COG3409	Peptidoglycan-binding domain 1 protein
AW20_1864	COG0561	phosphatase activity
AW20_1867	COG3527	Alpha-acetolactate decarboxylase
AW20_1868	COG0028	Belongs to the TPP enzyme family
AW20_187	COG5002	protein histidine kinase activity
AW20_1874	COG0189	ligase activity
AW20_1877	COG1126	abc transporter atp-binding protein
AW20_1878	COG0765	amino acid transport
AW20_1879	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_1880	COG1132	(ABC) transporter
AW20_1881	COG1132	(ABC) transporter
AW20_1882	COG1132	(ABC) transporter
AW20_1883	COG1012	belongs to the aldehyde dehydrogenase family
AW20_1885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW20_1886	COG0531	amino acid
AW20_1889	COG0693	protein deglycase activity
AW20_189	COG0561	phosphatase activity
AW20_1891	COG2211	Major facilitator Superfamily
AW20_1892	COG4533	DNA binding
AW20_1893	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_1895	COG1733	regulation of RNA biosynthetic process
AW20_1896	COG2814	Major facilitator Superfamily
AW20_1897	COG1309	transcriptional regulator
AW20_1898	COG2076	Multidrug Resistance protein
AW20_1901	COG1522	sequence-specific DNA binding
AW20_1902	COG0697	spore germination
AW20_1905	COG2259	Doxx family
AW20_1907	COG1263	PTS System
AW20_1907	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_1909	COG1737	Transcriptional regulator
AW20_1911	COG0475	glutathione-regulated potassium exporter activity
AW20_1912	COG0531	amino acid
AW20_1918	COG0586	Pfam SNARE associated Golgi protein
AW20_1925	COG3546	catalase activity
AW20_1926	COG1114	Component of the transport system for branched-chain amino acids
AW20_1929	COG5522	Integral membrane protein (intg_mem_TP0381)
AW20_1931	COG1136	(ABC) transporter
AW20_1932	COG0577	efflux transmembrane transporter activity
AW20_1933	COG3584	3D domain protein
AW20_1933	COG1388	LysM domain
AW20_1937	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_1938	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_1939	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_1939	COG3711	transcriptional antiterminator
AW20_1942	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW20_1943	COG0604	alcohol dehydrogenase
AW20_1944	COG1316	TRANSCRIPTIONal
AW20_1946	COG0730	response to heat
AW20_1947	COG2210	Belongs to the sulfur carrier protein TusA family
AW20_1949	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_1951	COG0425	Belongs to the sulfur carrier protein TusA family
AW20_1952	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_1952	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_1953	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_1953	COG0425	Belongs to the sulfur carrier protein TusA family
AW20_1954	COG1937	Protein conserved in bacteria
AW20_1955	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW20_196	COG2124	cytochrome p450
AW20_1960	COG2719	SpoVR family
AW20_1961	COG0778	Nitroreductase
AW20_1969	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW20_1970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_1972	COG1609	Transcriptional regulator
AW20_1973	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_1973	COG1263	PTS System
AW20_1974	COG1621	beta-fructofuranosidase activity
AW20_1975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW20_1979	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_1980	COG2252	PERMEase
AW20_1983	COG1846	Transcriptional regulator
AW20_1984	COG2814	Major facilitator Superfamily
AW20_1985	COG2205	protein histidine kinase activity
AW20_1992	COG0351	phosphomethylpyrimidine kinase
AW20_1993	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_1995	COG2104	thiamine diphosphate biosynthetic process
AW20_1996	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_1997	COG0352	thiamine-phosphate diphosphorylase activity
AW20_1998	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_1999	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_2	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW20_2000	COG1116	anion transmembrane transporter activity
AW20_2001	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW20_2005	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW20_2028	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW20_2030	COG0581	inorganic phosphate transmembrane transporter activity
AW20_2031	COG0573	inorganic phosphate transmembrane transporter activity
AW20_2032	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW20_2033	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_2033	COG1918	ferrous iron import across plasma membrane
AW20_2034	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_2035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_2037	COG0531	amino acid
AW20_2038	COG0697	spore germination
AW20_2039	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_2042	COG4990	cell redox homeostasis
AW20_2043	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW20_2044	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW20_2047	COG0569	domain protein
AW20_2047	COG0475	glutathione-regulated potassium exporter activity
AW20_2052	COG2252	PERMEase
AW20_2053	COG1113	amino acid transport
AW20_2056	COG1114	Component of the transport system for branched-chain amino acids
AW20_2057	COG3104	oligopeptide transport
AW20_2060	COG1476	TRANSCRIPTIONal
AW20_2061	COG1388	LysM domain
AW20_2061	COG3584	3D domain protein
AW20_2062	COG0840	transmembrane signaling receptor activity
AW20_2063	COG1968	undecaprenyl-diphosphatase activity
AW20_2068	COG3568	Endonuclease Exonuclease Phosphatase
AW20_2071	COG1063	alcohol dehydrogenase
AW20_2076	COG1879	ABC-type sugar transport system periplasmic component
AW20_2077	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW20_2080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW20_2081	COG1609	Transcriptional regulator
AW20_2082	COG0477	Major facilitator Superfamily
AW20_2083	COG0477	Major facilitator Superfamily
AW20_2084	COG1846	Transcriptional regulator
AW20_2085	COG2271	Major facilitator Superfamily
AW20_2087	COG4608	Belongs to the ABC transporter superfamily
AW20_2088	COG0601	transmembrane transport
AW20_2090	COG0747	negative chemotaxis
AW20_2093	COG0659	secondary active sulfate transmembrane transporter activity
AW20_2097	COG5002	protein histidine kinase activity
AW20_2098	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW20_2099	COG2378	regulation of single-species biofilm formation
AW20_2104	COG0833	amino acid
AW20_2105	COG0765	amino acid transport
AW20_2106	COG0765	amino acid transport
AW20_2107	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_2108	COG1126	abc transporter atp-binding protein
AW20_2109	COG1115	amino acid carrier protein
AW20_2110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_2112	COG0697	spore germination
AW20_2115	COG0366	Alpha amylase catalytic
AW20_2116	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_2116	COG1263	PTS System
AW20_2117	COG2188	Transcriptional regulator
AW20_2118	COG0531	amino acid
AW20_212	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW20_2122	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_2123	COG0714	Associated with various cellular activities
AW20_2124	COG4548	von Willebrand factor, type A
AW20_2126	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW20_2128	COG0156	8-amino-7-oxononanoate synthase activity
AW20_2129	COG2226	methyltransferase
AW20_2131	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2132	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2133	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_2134	COG3104	oligopeptide transport
AW20_2137	COG1620	l-lactate permease
AW20_2138	COG1027	Aspartate ammonia-lyase
AW20_2139	COG1253	flavin adenine dinucleotide binding
AW20_214	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_2140	COG0346	lactoylglutathione lyase activity
AW20_2141	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_2142	COG1316	TRANSCRIPTIONal
AW20_2143	COG2720	vancomycin resistance protein
AW20_2147	COG3227	Zinc metalloprotease (Elastase)
AW20_215	COG0460	homoserine dehydrogenase
AW20_2150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW20_2151	COG2217	Heavy metal translocating P-type atpase
AW20_2152	COG0640	Transcriptional regulator
AW20_2153	COG0531	amino acid
AW20_2158	COG3383	formate dehydrogenase (NAD+) activity
AW20_2159	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW20_2160	COG0456	acetyltransferase
AW20_2160	COG0454	-acetyltransferase
AW20_2162	COG0745	RESPONSE REGULATOR receiver
AW20_2163	COG5002	protein histidine kinase activity
AW20_2165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_2168	COG0281	malic enzyme
AW20_2169	COG3493	citrate carrier protein
AW20_2170	COG4565	transcriptional regulatory protein
AW20_2171	COG3290	protein histidine kinase activity
AW20_2173	COG4990	cell redox homeostasis
AW20_2175	COG5002	protein histidine kinase activity
AW20_2176	COG0745	RESPONSE REGULATOR receiver
AW20_2177	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW20_2179	COG0395	ABC-type sugar transport system, permease component
AW20_2180	COG1175	transmembrane transport
AW20_2181	COG3842	ATPase activity
AW20_2182	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW20_2186	COG2851	Citrate transporter
AW20_2189	COG3290	protein histidine kinase activity
AW20_219	COG0577	efflux transmembrane transporter activity
AW20_2191	COG2268	Band 7 protein
AW20_2192	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW20_2194	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_2198	COG2766	serine protein kinase
AW20_220	COG0577	efflux transmembrane transporter activity
AW20_2201	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW20_2203	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW20_2205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW20_2206	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW20_221	COG1136	(ABC) transporter
AW20_2231	COG0735	belongs to the Fur family
AW20_2232	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW20_2236	COG4555	ABC transporter
AW20_2238	COG0067	glutamate synthase
AW20_2238	COG0069	glutamate synthase activity
AW20_2238	COG0070	glutamate synthase
AW20_2239	COG4129	membrane
AW20_2240	COG1132	(ABC) transporter
AW20_2245	COG1194	a g-specific adenine glycosylase
AW20_2246	COG1988	membrane-bound metal-dependent
AW20_2252	COG1090	epimerase
AW20_2253	COG1228	amidohydrolase
AW20_2257	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW20_2260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW20_2260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW20_2263	COG0463	Glycosyl transferase, family 2
AW20_2266	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_2267	COG1263	PTS System
AW20_2267	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_227	COG2205	protein histidine kinase activity
AW20_2273	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_2274	COG0833	amino acid
AW20_2276	COG3829	transcription factor binding
AW20_2278	COG0101	tRNA pseudouridine synthase activity
AW20_229	COG0745	RESPONSE REGULATOR receiver
AW20_231	COG3773	Cell wall hydrolase
AW20_2325	COG1484	DNA-dependent DNA replication
AW20_2332	COG1396	sequence-specific DNA binding
AW20_2336	COG0582	viral genome integration into host DNA
AW20_2337	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW20_2338	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW20_234	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW20_2343	COG0535	radical SAM domain protein
AW20_2345	COG0387	Pfam Sodium calcium exchanger
AW20_2346	COG3871	stress protein (general stress protein 26)
AW20_2349	COG0586	Pfam SNARE associated Golgi protein
AW20_235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW20_2352	COG0681	Belongs to the peptidase S26 family
AW20_2354	COG0697	spore germination
AW20_2355	COG2217	Heavy metal translocating P-type atpase
AW20_2356	COG1295	ribonuclease BN
AW20_2358	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW20_2361	COG3853	Toxic anion resistance protein (TelA)
AW20_2363	COG0861	Integral membrane protein TerC family
AW20_2364	COG2310	stress, protein
AW20_2365	COG2310	stress, protein
AW20_2366	COG2310	stress, protein
AW20_2369	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_2372	COG2270	Major facilitator Superfamily
AW20_238	COG1063	alcohol dehydrogenase
AW20_2381	COG0488	(ABC) transporter
AW20_2382	COG1116	anion transmembrane transporter activity
AW20_2384	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_2387	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW20_2393	COG1263	PTS System
AW20_2393	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_2393	COG2190	(PTS) system
AW20_2394	COG0366	Alpha amylase catalytic
AW20_2395	COG0840	transmembrane signaling receptor activity
AW20_2396	COG0840	transmembrane signaling receptor activity
AW20_2398	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_2399	COG0765	amino acid transport
AW20_240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_2401	COG0723	plastoquinol--plastocyanin reductase activity
AW20_2401	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_2402	COG2814	Major facilitator Superfamily
AW20_2403	COG3541	Predicted nucleotidyltransferase
AW20_2407	COG5002	protein histidine kinase activity
AW20_2413	COG0166	Belongs to the GPI family
AW20_2416	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_2417	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2418	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2422	COG0450	alkyl hydroperoxide reductase
AW20_2426	COG1473	amidohydrolase
AW20_2432	COG4807	Protein conserved in bacteria
AW20_2434	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW20_2435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW20_2436	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_2439	COG2309	aminopeptidase activity
AW20_244	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_2440	COG2076	Multidrug Resistance protein
AW20_2441	COG1012	belongs to the aldehyde dehydrogenase family
AW20_2443	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW20_2444	COG0546	phosphoglycolate phosphatase activity
AW20_2445	COG1597	lipid kinase activity
AW20_2450	COG1846	Transcriptional regulator
AW20_2451	COG0003	Pfam Anion-transporting ATPase
AW20_2452	COG0003	Pfam Anion-transporting ATPase
AW20_2455	COG1464	Belongs to the NlpA lipoprotein family
AW20_2456	COG2011	ABC-type metal ion transport system permease component
AW20_2457	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_2458	COG1335	isochorismatase
AW20_2462	COG4851	CamS sex pheromone cAM373 precursor
AW20_2464	COG0210	DNA helicase
AW20_2469	COG0151	Belongs to the GarS family
AW20_2471	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW20_2473	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW20_2476	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW20_2478	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW20_2479	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW20_248	COG2814	Major facilitator Superfamily
AW20_2480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW20_2485	COG0745	RESPONSE REGULATOR receiver
AW20_2486	COG2205	protein histidine kinase activity
AW20_2489	COG1968	undecaprenyl-diphosphatase activity
AW20_2494	COG1215	transferase activity, transferring glycosyl groups
AW20_2500	COG2226	methyltransferase
AW20_2507	COG5002	protein histidine kinase activity
AW20_2509	COG2252	PERMEase
AW20_2513	COG1266	CAAX protease self-immunity
AW20_2516	COG0488	(ABC) transporter
AW20_2518	COG0456	acetyltransferase
AW20_2519	COG1214	PFAM Peptidase M22, glycoprotease
AW20_2520	COG0802	atpase or kinase
AW20_253	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_253	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_2539	COG2183	response to ionizing radiation
AW20_2540	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW20_2541	COG0864	Transcriptional regulator
AW20_2542	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW20_2543	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW20_2545	COG4294	response to UV
AW20_2546	COG0457	Tetratricopeptide repeat
AW20_2546	COG0705	Rhomboid family
AW20_2548	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW20_2551	COG2814	Major facilitator Superfamily
AW20_2553	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW20_2554	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AW20_2557	COG0561	phosphatase activity
AW20_2558	COG4608	Belongs to the ABC transporter superfamily
AW20_2559	COG0561	phosphatase activity
AW20_2560	COG0444	Belongs to the ABC transporter superfamily
AW20_2562	COG0601	transmembrane transport
AW20_2563	COG0747	negative chemotaxis
AW20_2566	COG0488	(ABC) transporter
AW20_2570	COG5298	Protein conserved in bacteria
AW20_2571	COG0084	hydrolase, TatD family'
AW20_2574	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_2576	COG1609	Transcriptional regulator
AW20_2578	COG0204	Acyl-transferase
AW20_258	COG3227	Zinc metalloprotease (Elastase)
AW20_2581	COG0697	spore germination
AW20_2582	COG0583	DNA-binding transcription factor activity
AW20_2585	COG1910	domain protein
AW20_2586	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW20_2587	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW20_2588	COG4149	molybdate abc transporter
AW20_2591	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_2592	COG0656	L-ascorbic acid biosynthetic process
AW20_2593	COG4166	transmembrane transport
AW20_2594	COG4166	transmembrane transport
AW20_2597	COG2207	Transcriptional regulator
AW20_2599	COG4166	transmembrane transport
AW20_2600	COG4608	Belongs to the ABC transporter superfamily
AW20_2601	COG0444	Belongs to the ABC transporter superfamily
AW20_2602	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_2603	COG0601	transmembrane transport
AW20_2606	COG2814	Major facilitator Superfamily
AW20_2608	COG2271	Major facilitator Superfamily
AW20_2609	COG0277	FAD linked oxidase domain protein
AW20_2611	COG0604	alcohol dehydrogenase
AW20_2612	COG1464	Belongs to the NlpA lipoprotein family
AW20_2613	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_2614	COG2011	ABC-type metal ion transport system permease component
AW20_2615	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_262	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW20_2623	COG0823	Involved in the tonB-independent uptake of proteins
AW20_2623	COG4946	Tricorn protease homolog
AW20_2623	COG1506	peptidase
AW20_2624	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW20_2629	COG0596	Alpha beta hydrolase
AW20_2630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW20_2632	COG4856	YbbR-like protein
AW20_2633	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW20_2651	COG0726	polysaccharide deacetylase
AW20_2652	COG2194	sulfuric ester hydrolase activity
AW20_2654	COG0489	protein tyrosine kinase activity
AW20_2655	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_2660	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW20_2667	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW20_2669	COG0024	Methionine aminopeptidase
AW20_2671	COG0201	protein transport
AW20_2683	COG0255	Belongs to the universal ribosomal protein uL29 family
AW20_269	COG2318	DinB family
AW20_2697	COG1358	cellular component organization or biogenesis
AW20_2698	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW20_27	COG2333	competence protein COMEC
AW20_27	COG0658	competence protein
AW20_2700	COG2813	Specifically methylates the guanine in position
AW20_2704	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AW20_2705	COG0250	Participates in transcription elongation, termination and antitermination
AW20_2706	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW20_2708	COG3688	RNA-binding protein containing a PIN domain
AW20_2709	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW20_271	COG0572	uridine kinase
AW20_2712	COG1045	serine acetyltransferase
AW20_2716	COG4956	integral membrane protein (PIN domain superfamily)
AW20_2718	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW20_2719	COG0542	response to heat
AW20_272	COG1247	-acetyltransferase
AW20_2721	COG3880	PFAM UvrB UvrC protein
AW20_2728	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW20_2729	COG1396	sequence-specific DNA binding
AW20_2730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW20_2731	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW20_2732	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW20_2733	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_2734	COG0512	Glutamine amidotransferase of anthranilate synthase
AW20_2735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW20_2736	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_2739	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW20_274	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_2741	COG0037	tRNA processing
AW20_2742	COG2208	phosphoserine phosphatase activity
AW20_2745	COG1098	S1 RNA binding domain
AW20_2749	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW20_275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW20_2750	COG3956	TIGRFAM MazG family protein
AW20_2751	COG2244	polysaccharide biosynthetic process
AW20_2752	COG2002	toxin-antitoxin pair type II binding
AW20_2753	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW20_2759	COG0251	oxidation-reduction process
AW20_276	COG1024	Enoyl-CoA hydratase
AW20_2760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW20_2763	COG4466	Protein conserved in bacteria
AW20_2766	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW20_2767	COG0084	hydrolase, TatD family'
AW20_2768	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_2768	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_2769	COG2002	toxin-antitoxin pair type II binding
AW20_277	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW20_2770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW20_2772	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW20_2774	COG1774	PSP1 C-terminal conserved region
AW20_2775	COG0470	DNA polymerase III
AW20_2777	COG1982	Orn Lys Arg decarboxylase major
AW20_278	COG0511	ligase activity, forming carbon-carbon bonds
AW20_2789	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW20_279	COG0439	Biotin carboxylase
AW20_2790	COG0590	tRNA wobble adenosine to inosine editing
AW20_2791	COG1335	isochorismatase
AW20_2792	COG1428	Deoxynucleoside kinase
AW20_2793	COG1428	Deoxynucleoside kinase
AW20_2799	COG1686	Belongs to the peptidase S11 family
AW20_280	COG1960	acyl-CoA dehydrogenase activity
AW20_2800	COG0517	IMP dehydrogenase activity
AW20_2800	COG0516	GMP reductase activity
AW20_2808	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW20_2809	COG0187	DNA topoisomerase II activity
AW20_2811	COG2501	S4 domain
AW20_2812	COG0592	DNA-directed DNA polymerase activity
AW20_2814	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AW20_2816	COG0706	membrane insertase activity
AW20_2817	COG1847	R3H domain protein
AW20_2822	COG1192	Involved in chromosome partitioning
AW20_2823	COG1475	DNA binding
AW20_2825	COG0668	transmembrane transport
AW20_2826	COG4481	Protein conserved in bacteria
AW20_2827	COG0012	GTP binding
AW20_2829	COG0629	single-stranded DNA binding
AW20_283	COG1309	transcriptional regulator
AW20_2831	COG4241	membrane
AW20_2832	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW20_2834	COG0305	Participates in initiation and elongation during chromosome replication
AW20_2840	COG0745	RESPONSE REGULATOR receiver
AW20_2841	COG5002	protein histidine kinase activity
AW20_2842	COG4863	YycH protein
AW20_2843	COG4853	Protein conserved in bacteria
AW20_2844	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW20_2845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_2849	COG1164	Oligoendopeptidase f
AW20_285	COG1131	(ABC) transporter
AW20_2850	COG0516	GMP reductase activity
AW20_2854	COG1272	protein, Hemolysin III
AW20_2855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW20_2859	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_2860	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW20_2861	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_2862	COG2814	Major facilitator Superfamily
AW20_2863	COG3275	phosphorelay sensor kinase activity
AW20_2864	COG3279	Response regulator of the LytR AlgR family
AW20_2867	COG0628	permease
AW20_2868	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_2868	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_2869	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW20_2870	COG1309	transcriptional regulator
AW20_2871	COG0463	Glycosyl transferase, family 2
AW20_2877	COG0488	(ABC) transporter
AW20_288	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_2880	COG1607	acyl-coa hydrolase
AW20_2882	COG0840	transmembrane signaling receptor activity
AW20_2887	COG0477	Major facilitator Superfamily
AW20_2888	COG3279	Response regulator of the LytR AlgR family
AW20_2889	COG1966	Carbon starvation protein
AW20_289	COG1252	NADH dehydrogenase
AW20_2890	COG2879	small protein
AW20_2891	COG3706	GGDEF domain
AW20_2892	COG0351	phosphomethylpyrimidine kinase
AW20_2893	COG2203	Gaf domain
AW20_2893	COG4585	Histidine kinase
AW20_2894	COG4585	Histidine kinase
AW20_2894	COG2203	Gaf domain
AW20_2895	COG2197	response regulator
AW20_2897	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW20_2898	COG1011	Hydrolase
AW20_2900	COG2873	o-acetylhomoserine
AW20_2902	COG0460	homoserine dehydrogenase
AW20_2904	COG1609	Transcriptional regulator
AW20_2905	COG2755	lipolytic protein G-D-S-L family
AW20_2906	COG1131	(ABC) transporter
AW20_2907	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_2909	COG2814	Major facilitator Superfamily
AW20_291	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_2910	COG0561	phosphatase activity
AW20_2911	COG2233	PERMEase
AW20_2915	COG2363	Small membrane protein
AW20_2917	COG3773	Cell wall hydrolase
AW20_2920	COG0280	phosphate acetyltransferase
AW20_2921	COG0095	Lipoate-protein ligase
AW20_2925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2926	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2927	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_2928	COG1120	ATPase activity
AW20_2929	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_2930	COG1078	dGTPase activity
AW20_2932	COG1994	Peptidase M50
AW20_2934	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_2935	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_2936	COG0789	Transcriptional regulator
AW20_2937	COG2814	Major facilitator Superfamily
AW20_2939	COG0010	Belongs to the arginase family
AW20_2942	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_2943	COG4506	Protein conserved in bacteria
AW20_2944	COG0018	arginyl-trna synthetase
AW20_2945	COG1595	DNA-templated transcription, initiation
AW20_2949	COG2234	aminopeptidase activity
AW20_295	COG1309	transcriptional regulator
AW20_2953	COG0024	Methionine aminopeptidase
AW20_2954	COG1131	(ABC) transporter
AW20_2955	COG0842	Transport permease protein
AW20_2956	COG4585	Histidine kinase
AW20_2957	COG2197	response regulator
AW20_2961	COG3300	MHYT domain
AW20_2961	COG5001	Diguanylate cyclase
AW20_2963	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_2964	COG2181	nitrate reductase activity
AW20_2964	COG0247	lactate metabolic process
AW20_2965	COG0183	Belongs to the thiolase family
AW20_2966	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW20_2967	COG1960	acyl-CoA dehydrogenase activity
AW20_2968	COG1960	acyl-CoA dehydrogenase activity
AW20_2970	COG3343	RNA polymerase activity
AW20_2972	COG4821	SIS domain
AW20_2976	COG1494	fructose-1,6-bisphosphatase
AW20_2977	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW20_2981	COG2890	protein-(glutamine-N5) methyltransferase activity
AW20_2984	COG0009	L-threonylcarbamoyladenylate synthase
AW20_2987	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW20_2988	COG2259	Doxx family
AW20_2989	COG2190	(PTS) system
AW20_2991	COG0698	ribose 5-phosphate isomerase
AW20_2997	COG0356	it plays a direct role in the translocation of protons across the membrane
AW20_300	COG1876	peptidase activity
AW20_3007	COG5001	Diguanylate cyclase
AW20_3007	COG3300	MHYT domain
AW20_3010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW20_3011	COG0649	NAD binding
AW20_3014	COG0839	Belongs to the complex I subunit 6 family
AW20_3016	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW20_3017	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW20_3018	COG1007	ATP synthesis coupled electron transport
AW20_3019	COG4836	Membrane
AW20_3022	COG2385	sporulation resulting in formation of a cellular spore
AW20_3023	COG4555	ABC transporter
AW20_3024	COG3279	Response regulator of the LytR AlgR family
AW20_3027	COG0739	heme binding
AW20_3029	COG1609	Transcriptional regulator
AW20_303	COG1476	TRANSCRIPTIONal
AW20_3037	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW20_3038	COG1682	transport, permease protein
AW20_3039	COG1134	teichoic acid transport
AW20_304	COG0457	Tetratricopeptide repeat
AW20_3040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW20_3043	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW20_3044	COG0745	RESPONSE REGULATOR receiver
AW20_3045	COG5002	protein histidine kinase activity
AW20_3052	COG1136	(ABC) transporter
AW20_3053	COG0577	efflux transmembrane transporter activity
AW20_3061	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_3062	COG4715	Zinc finger, swim domain protein
AW20_3067	COG3584	3D domain protein
AW20_3067	COG1388	LysM domain
AW20_3068	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_3073	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_3074	COG1388	LysM domain
AW20_3074	COG0791	NLP P60 protein
AW20_3077	COG1368	sulfuric ester hydrolase activity
AW20_308	COG0737	Belongs to the 5'-nucleotidase family
AW20_3080	COG2389	metal-binding protein
AW20_3082	COG1620	l-lactate permease
AW20_3084	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_3085	COG1294	oxidase, subunit
AW20_3086	COG1271	oxidase subunit
AW20_3090	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW20_3091	COG0583	DNA-binding transcription factor activity
AW20_3092	COG1511	domain protein
AW20_3093	COG0346	lactoylglutathione lyase activity
AW20_3095	COG1301	dicarboxylic acid transport
AW20_3096	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_3098	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_3099	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW20_3100	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW20_3102	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_3103	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_3104	COG1486	melibiose metabolic process
AW20_3105	COG3394	polysaccharide catabolic process
AW20_3108	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW20_3108	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW20_3110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW20_3111	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW20_3112	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW20_3113	COG1316	TRANSCRIPTIONal
AW20_3114	COG1739	Uncharacterized protein family UPF0029
AW20_3115	COG1307	EDD domain protein, DegV family
AW20_3116	COG1733	regulation of RNA biosynthetic process
AW20_3117	COG1388	LysM domain
AW20_3117	COG0791	NLP P60 protein
AW20_3118	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW20_3119	COG1040	competence protein
AW20_312	COG3718	enzyme involved in inositol metabolism
AW20_3120	COG1278	Cold shock
AW20_3121	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW20_3122	COG0653	protein targeting
AW20_3123	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW20_3125	COG2884	Cell division ATP-binding protein ftsE
AW20_3126	COG2177	Part of the ABC transporter FtsEX involved in
AW20_3127	COG0793	Belongs to the peptidase S41A family
AW20_3127	COG3409	Peptidoglycan-binding domain 1 protein
AW20_3128	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_3129	COG1132	(ABC) transporter
AW20_313	COG0191	fructose-bisphosphate aldolase activity
AW20_3132	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW20_3134	COG0583	DNA-binding transcription factor activity
AW20_3135	COG2855	membrane
AW20_3139	COG0789	Transcriptional regulator
AW20_3143	COG0556	nucleotide-excision repair
AW20_3144	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_3146	COG1950	PFAM Membrane protein of
AW20_3150	COG0110	maltose O-acetyltransferase activity
AW20_3151	COG0457	Tetratricopeptide repeat
AW20_3152	COG0492	ferredoxin-NADP+ reductase activity
AW20_3154	COG1051	belongs to the nudix hydrolase family
AW20_3156	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW20_3158	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_3159	COG0740	serine-type endopeptidase activity
AW20_3160	COG2323	membrane
AW20_3163	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_3168	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW20_317	COG1012	belongs to the aldehyde dehydrogenase family
AW20_3171	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW20_3173	COG0149	triose-phosphate isomerase activity
AW20_3174	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW20_3176	COG4974	Belongs to the 'phage' integrase family
AW20_3181	COG4695	Portal protein
AW20_319	COG0673	inositol 2-dehydrogenase activity
AW20_32	COG2205	protein histidine kinase activity
AW20_320	COG2814	Major facilitator Superfamily
AW20_3200	COG1346	cytolysis
AW20_3201	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW20_3202	COG1647	Serine aminopeptidase, S33
AW20_3203	COG0557	exoribonuclease II activity
AW20_321	COG1609	Transcriptional regulator
AW20_3213	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_3216	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW20_3217	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW20_3219	COG0840	transmembrane signaling receptor activity
AW20_3219	COG3290	protein histidine kinase activity
AW20_322	COG0671	phosphoesterase, PA-phosphatase related
AW20_3221	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW20_3222	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW20_3223	COG1252	NADH dehydrogenase
AW20_3225	COG1733	regulation of RNA biosynthetic process
AW20_3226	COG2814	Major facilitator Superfamily
AW20_3227	COG0656	L-ascorbic acid biosynthetic process
AW20_323	COG2367	Beta-lactamase
AW20_3232	COG2910	NAD(P)H-binding
AW20_3233	COG1115	amino acid carrier protein
AW20_3234	COG1115	amino acid carrier protein
AW20_3235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_3236	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_3238	COG2311	Membrane
AW20_3241	COG1611	Belongs to the LOG family
AW20_3244	COG0783	Belongs to the Dps family
AW20_3245	COG1115	amino acid carrier protein
AW20_3246	COG0490	domain, Protein
AW20_3247	COG0475	glutathione-regulated potassium exporter activity
AW20_3250	COG1741	Belongs to the pirin family
AW20_3251	COG3227	Zinc metalloprotease (Elastase)
AW20_3252	COG2151	metal-sulfur cluster biosynthetic enzyme
AW20_3257	COG5002	protein histidine kinase activity
AW20_3258	COG0745	RESPONSE REGULATOR receiver
AW20_3259	COG1376	ErfK ybiS ycfS ynhG family protein
AW20_326	COG0768	penicillin binding
AW20_3261	COG0586	Pfam SNARE associated Golgi protein
AW20_3268	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_3270	COG0706	membrane insertase activity
AW20_3272	COG0531	amino acid
AW20_3273	COG2814	Major facilitator Superfamily
AW20_3277	COG0840	transmembrane signaling receptor activity
AW20_3278	COG0011	TIGRFAM Protein of
AW20_328	COG1595	DNA-templated transcription, initiation
AW20_3281	COG1686	Belongs to the peptidase S11 family
AW20_3283	COG1024	Enoyl-CoA hydratase
AW20_3283	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW20_3284	COG0183	Belongs to the thiolase family
AW20_3285	COG1960	acyl-CoA dehydrogenase activity
AW20_3286	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_3287	COG1309	transcriptional regulator
AW20_3292	COG0039	L-malate dehydrogenase activity
AW20_3301	COG1393	Belongs to the ArsC family
AW20_3303	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW20_3304	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_3306	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_3307	COG2011	ABC-type metal ion transport system permease component
AW20_3308	COG1464	Belongs to the NlpA lipoprotein family
AW20_3309	COG1464	Belongs to the NlpA lipoprotein family
AW20_3310	COG0396	ATPase activity
AW20_3311	COG0719	Fe-S assembly protein
AW20_3312	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW20_3313	COG0822	iron-sulfur transferase activity
AW20_3314	COG0719	Fe-S assembly protein
AW20_3316	COG1695	Transcriptional regulator
AW20_3317	COG0737	Belongs to the 5'-nucleotidase family
AW20_3318	COG3377	Domain of unknown function (DUF1805)
AW20_332	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW20_3320	COG0739	heme binding
AW20_3325	COG4377	Putative membrane peptidase family (DUF2324)
AW20_3326	COG0789	Transcriptional regulator
AW20_3328	COG4470	Protein conserved in bacteria
AW20_3331	COG1494	fructose-1,6-bisphosphatase
AW20_3332	COG2445	Protein of unknown function DUF86
AW20_3334	COG0647	UMP catabolic process
AW20_3335	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_3337	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW20_3338	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_3340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW20_3341	COG4837	Protein of unknown function (DUF1462)
AW20_3349	COG2824	Alkylphosphonate utilization operon protein PhnA
AW20_3350	COG0390	transport system, permease component
AW20_3352	COG1252	NADH dehydrogenase
AW20_3355	COG0316	Belongs to the HesB IscA family
AW20_3358	COG1683	Conserved Protein
AW20_3361	COG3708	Transcriptional regulator
AW20_3364	COG1252	NADH dehydrogenase
AW20_3367	COG3584	3D domain protein
AW20_3370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW20_3371	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW20_3373	COG1268	BioY protein
AW20_3375	COG2050	protein possibly involved in aromatic compounds catabolism
AW20_3379	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_3380	COG5018	Exonuclease
AW20_3384	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW20_3386	COG2267	carboxylic ester hydrolase activity
AW20_3387	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW20_3388	COG1522	sequence-specific DNA binding
AW20_3389	COG0436	Aminotransferase
AW20_3390	COG1098	S1 RNA binding domain
AW20_3391	COG2155	Conserved Protein
AW20_3392	COG0166	Belongs to the GPI family
AW20_3393	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW20_3395	COG1285	pathogenesis
AW20_340	COG1846	Transcriptional regulator
AW20_3403	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW20_341	COG3961	Belongs to the TPP enzyme family
AW20_342	COG2226	methyltransferase
AW20_3425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW20_3426	COG0297	glycogen (starch) synthase activity
AW20_3427	COG0058	SHG alpha-glucan phosphorylase activity
AW20_3432	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW20_3433	COG1575	Belongs to the MenA family. Type 1 subfamily
AW20_3434	COG1169	isochorismate synthase
AW20_3435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW20_3436	COG0596	Alpha beta hydrolase
AW20_3437	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW20_3439	COG4948	Mandelate Racemase Muconate Lactonizing
AW20_344	COG3615	Tellurite resistance protein tehB
AW20_344	COG0500	methyltransferase
AW20_3445	COG3964	amidohydrolase
AW20_3449	COG2188	Transcriptional regulator
AW20_345	COG1136	(ABC) transporter
AW20_345	COG0577	efflux transmembrane transporter activity
AW20_3452	COG0577	efflux transmembrane transporter activity
AW20_3453	COG0577	efflux transmembrane transporter activity
AW20_3454	COG1136	(ABC) transporter
AW20_3455	COG0577	efflux transmembrane transporter activity
AW20_3456	COG0577	efflux transmembrane transporter activity
AW20_3458	COG0577	efflux transmembrane transporter activity
AW20_3459	COG2205	protein histidine kinase activity
AW20_3460	COG0745	RESPONSE REGULATOR receiver
AW20_3461	COG3708	Transcriptional regulator
AW20_3461	COG2207	Transcriptional regulator
AW20_3462	COG1136	(ABC) transporter
AW20_3463	COG0577	efflux transmembrane transporter activity
AW20_3465	COG0586	Pfam SNARE associated Golgi protein
AW20_3472	COG1597	lipid kinase activity
AW20_3478	COG0745	RESPONSE REGULATOR receiver
AW20_3479	COG5002	protein histidine kinase activity
AW20_348	COG1309	transcriptional regulator
AW20_3486	COG1842	Phage shock protein A
AW20_3491	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_3495	COG1294	oxidase, subunit
AW20_3496	COG1271	oxidase subunit
AW20_3498	COG0288	reversible hydration of carbon dioxide
AW20_3503	COG0494	nUDIX hydrolase
AW20_3505	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW20_3509	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_3510	COG1116	anion transmembrane transporter activity
AW20_3511	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_3515	COG1368	sulfuric ester hydrolase activity
AW20_3516	COG2267	carboxylic ester hydrolase activity
AW20_3517	COG4191	Histidine kinase
AW20_3518	COG5002	protein histidine kinase activity
AW20_3519	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW20_3529	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW20_353	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_3531	COG0438	transferase activity, transferring glycosyl groups
AW20_3532	COG0671	phosphoesterase, PA-phosphatase related
AW20_3533	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW20_3534	COG2267	carboxylic ester hydrolase activity
AW20_3538	COG1794	racemase activity, acting on amino acids and derivatives
AW20_3540	COG1131	(ABC) transporter
AW20_3541	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW20_3542	COG1242	4 iron, 4 sulfur cluster binding
AW20_3546	COG1136	(ABC) transporter
AW20_3548	COG0582	viral genome integration into host DNA
AW20_3549	COG0490	domain, Protein
AW20_3550	COG0475	glutathione-regulated potassium exporter activity
AW20_3551	COG2814	Major facilitator Superfamily
AW20_3559	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AW20_356	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW20_3561	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_3565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW20_3566	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_3568	COG0303	'Molybdopterin
AW20_3569	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW20_357	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_3570	COG0314	molybdopterin synthase activity
AW20_3573	COG4975	Glucose uptake
AW20_3575	COG1329	Transcriptional regulator
AW20_3579	COG3832	glyoxalase III activity
AW20_358	COG2971	BadF BadG BcrA BcrD
AW20_3581	COG2814	Major facilitator Superfamily
AW20_3582	COG2081	HI0933 family
AW20_3583	COG2244	polysaccharide biosynthetic process
AW20_3584	COG1187	pseudouridine synthase activity
AW20_3585	COG1349	DNA-binding transcription factor activity
AW20_3586	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_3587	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_3589	COG1523	belongs to the glycosyl hydrolase 13 family
AW20_3590	COG0510	thiamine kinase activity
AW20_3593	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_3595	COG1363	Peptidase, m42
AW20_3596	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AW20_3597	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_3598	COG4848	Belongs to the UPF0354 family
AW20_3599	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_36	COG3397	chitin binding
AW20_3601	COG1674	ftsk spoiiie
AW20_3604	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_3608	COG2309	aminopeptidase activity
AW20_3610	COG3118	belongs to the thioredoxin family
AW20_3611	COG4851	CamS sex pheromone cAM373 precursor
AW20_3612	COG1609	Transcriptional regulator
AW20_3619	COG0666	response to abiotic stimulus
AW20_3621	COG0745	RESPONSE REGULATOR receiver
AW20_3623	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW20_3624	COG0517	IMP dehydrogenase activity
AW20_3625	COG0454	-acetyltransferase
AW20_3626	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_3628	COG1595	DNA-templated transcription, initiation
AW20_363	COG1649	PFAM Uncharacterised BCR, COG1649
AW20_3634	COG0626	cystathionine gamma-synthase activity
AW20_3635	COG1956	GAF domain-containing protein
AW20_3636	COG1309	transcriptional regulator
AW20_3637	COG1309	transcriptional regulator
AW20_3638	COG0697	spore germination
AW20_3639	COG0583	DNA-binding transcription factor activity
AW20_3641	COG1104	cysteine desulfurase activity
AW20_3644	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_3646	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW20_3649	COG3874	Sporulation protein YtfJ
AW20_3650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW20_3651	COG0827	DNA restriction-modification system
AW20_3652	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW20_3656	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_3665	COG0589	response to stress
AW20_3666	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_3669	COG1476	TRANSCRIPTIONal
AW20_3671	COG0662	Cupin 2, conserved barrel domain protein
AW20_3672	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_3679	COG0006	proline dipeptidase activity
AW20_368	COG1595	DNA-templated transcription, initiation
AW20_3682	COG4109	DRTGG domain
AW20_3686	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW20_3689	COG0587	DNA-directed DNA polymerase activity
AW20_369	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AW20_3690	COG0281	malic enzyme
AW20_3691	COG1725	Transcriptional regulator
AW20_3696	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW20_3697	COG0628	permease
AW20_3699	COG0372	Belongs to the citrate synthase family
AW20_37	COG2153	protein acetylation
AW20_3700	COG0538	isocitrate dehydrogenase activity
AW20_3704	COG0745	RESPONSE REGULATOR receiver
AW20_3705	COG5002	protein histidine kinase activity
AW20_3706	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_3706	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_3708	COG1971	Probably functions as a manganese efflux pump
AW20_3709	COG0237	dephospho-CoA kinase activity
AW20_3710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW20_3711	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW20_3713	COG3611	Membrane attachment protein
AW20_3714	COG1484	DNA-dependent DNA replication
AW20_3716	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_3721	COG1363	Peptidase, m42
AW20_3722	COG1309	transcriptional regulator
AW20_3723	COG1566	PFAM secretion protein HlyD family protein
AW20_3724	COG2814	Major facilitator Superfamily
AW20_3729	COG1418	mRNA catabolic process
AW20_373	COG1396	sequence-specific DNA binding
AW20_3731	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW20_3740	COG1286	toxin biosynthetic process
AW20_3741	COG1796	DNA polymerase
AW20_3741	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW20_3742	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW20_3742	COG1796	DNA polymerase
AW20_3745	COG1187	pseudouridine synthase activity
AW20_3746	COG1114	Component of the transport system for branched-chain amino acids
AW20_3747	COG5386	Cell surface protein
AW20_3749	COG5386	Cell surface protein
AW20_3752	COG1120	ATPase activity
AW20_3753	COG4509	Sortase family
AW20_3756	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW20_3757	COG4895	conserved protein (DUF2196)
AW20_3759	COG0745	RESPONSE REGULATOR receiver
AW20_3760	COG2205	protein histidine kinase activity
AW20_3761	COG1131	(ABC) transporter
AW20_3767	COG2318	DinB family
AW20_377	COG1132	(ABC) transporter
AW20_3771	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_3772	COG1309	transcriptional regulator
AW20_3773	COG1024	Enoyl-CoA hydratase
AW20_3774	COG2086	electron transfer activity
AW20_3775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW20_3776	COG3118	belongs to the thioredoxin family
AW20_3778	COG1719	4-vinyl reductase, 4VR
AW20_3779	COG2009	succinate dehydrogenase
AW20_378	COG1132	(ABC) transporter
AW20_3780	COG1053	succinate dehydrogenase
AW20_3781	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW20_3782	COG0824	Thioesterase
AW20_3783	COG1876	peptidase activity
AW20_3784	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW20_3785	COG1360	Flagellar Motor Protein
AW20_3786	COG1360	Flagellar Motor Protein
AW20_3787	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AW20_3788	COG4152	abc transporter atp-binding protein
AW20_3789	COG1668	transmembrane transport
AW20_3790	COG1959	2 iron, 2 sulfur cluster binding
AW20_3792	COG0697	spore germination
AW20_3793	COG1396	sequence-specific DNA binding
AW20_3794	COG1983	PspC domain protein
AW20_3797	COG3279	Response regulator of the LytR AlgR family
AW20_3798	COG3275	phosphorelay sensor kinase activity
AW20_3799	COG4608	Belongs to the ABC transporter superfamily
AW20_38	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AW20_3800	COG0444	Belongs to the ABC transporter superfamily
AW20_3804	COG0402	S-adenosylhomocysteine deaminase activity
AW20_3805	COG0402	S-adenosylhomocysteine deaminase activity
AW20_3807	COG2233	PERMEase
AW20_3808	COG2197	response regulator
AW20_381	COG2258	MOSC domain
AW20_3811	COG1309	transcriptional regulator
AW20_3815	COG5401	PFAM Sporulation and spore germination
AW20_3818	COG0622	Phosphoesterase
AW20_382	COG0583	DNA-binding transcription factor activity
AW20_3828	COG1067	ATP-dependent peptidase activity
AW20_3828	COG0470	DNA polymerase III
AW20_3831	COG1764	response to oxidative stress
AW20_3832	COG1846	Transcriptional regulator
AW20_3834	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW20_3836	COG1587	Uroporphyrinogen-III synthase
AW20_3837	COG0113	porphobilinogen synthase activity
AW20_3839	COG1388	LysM domain
AW20_3841	COG0525	valine-tRNA ligase activity
AW20_3842	COG0285	dihydrofolate synthase activity
AW20_3846	COG1077	Cell shape determining protein MreB Mrl
AW20_385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW20_3850	COG2894	cell division
AW20_3851	COG0739	heme binding
AW20_3852	COG1994	Peptidase M50
AW20_3853	COG1530	ribonuclease E activity
AW20_3855	COG2868	ribosomal protein
AW20_3857	COG3290	protein histidine kinase activity
AW20_3858	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW20_3859	COG0745	RESPONSE REGULATOR receiver
AW20_386	COG0583	DNA-binding transcription factor activity
AW20_3861	COG5002	protein histidine kinase activity
AW20_3862	COG1136	(ABC) transporter
AW20_3863	COG0577	efflux transmembrane transporter activity
AW20_3864	COG0577	efflux transmembrane transporter activity
AW20_3865	COG0077	Prephenate dehydratase
AW20_3866	COG2258	MOSC domain
AW20_3867	COG1827	regulation of RNA biosynthetic process
AW20_3868	COG1104	cysteine desulfurase activity
AW20_3869	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW20_3870	COG0157	Belongs to the NadC ModD family
AW20_3875	COG0640	Transcriptional regulator
AW20_3876	COG0697	spore germination
AW20_3877	COG0697	spore germination
AW20_3879	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW20_3885	COG1862	Preprotein translocase
AW20_3887	COG2323	membrane
AW20_3888	COG2244	polysaccharide biosynthetic process
AW20_3890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW20_3890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW20_3891	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW20_3892	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW20_3892	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW20_3894	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW20_3899	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW20_3900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW20_3901	COG1959	2 iron, 2 sulfur cluster binding
AW20_3902	COG1104	cysteine desulfurase activity
AW20_3903	COG0482	sulfurtransferase activity
AW20_3905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW20_3909	COG0628	permease
AW20_3911	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_3915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW20_3916	COG4122	O-methyltransferase activity
AW20_3921	COG0768	penicillin binding
AW20_3926	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_3927	COG0626	cystathionine gamma-synthase activity
AW20_3928	COG1012	belongs to the aldehyde dehydrogenase family
AW20_3928	COG1454	alcohol dehydrogenase
AW20_3930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_3938	COG2259	Doxx family
AW20_3939	COG2514	catechol 2,3-dioxygenase activity
AW20_394	COG0561	phosphatase activity
AW20_3940	COG2514	catechol 2,3-dioxygenase activity
AW20_3942	COG3186	Phenylalanine-4-hydroxylase
AW20_3943	COG1404	Belongs to the peptidase S8 family
AW20_395	COG0010	Belongs to the arginase family
AW20_3950	COG2267	carboxylic ester hydrolase activity
AW20_3952	COG1785	Belongs to the alkaline phosphatase family
AW20_3954	COG2357	RelA SpoT domain protein
AW20_3955	COG0778	Nitroreductase
AW20_3957	COG1595	DNA-templated transcription, initiation
AW20_3963	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW20_3964	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW20_3966	COG1534	Rna-binding protein
AW20_3968	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW20_3969	COG0799	negative regulation of ribosome biogenesis
AW20_3970	COG2226	methyltransferase
AW20_3971	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_3972	COG1596	polysaccharide export
AW20_3972	COG1555	photosystem II stabilization
AW20_3973	COG2131	deaminase
AW20_3974	COG0658	competence protein
AW20_3974	COG2333	competence protein COMEC
AW20_3976	COG1466	dna polymerase III delta subunit
AW20_398	COG1278	Cold shock
AW20_3981	COG1733	regulation of RNA biosynthetic process
AW20_3982	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW20_3988	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW20_3989	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW20_3990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW20_3991	COG1610	YqeY-like protein
AW20_3994	COG1702	phosphate starvation-inducible protein PhoH
AW20_3995	COG1480	7TM receptor with intracellular HD hydrolase
AW20_3997	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW20_3998	COG0295	cytidine deaminase activity
AW20_3999	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW20_4	COG3397	chitin binding
AW20_400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_4002	COG0517	IMP dehydrogenase activity
AW20_4004	COG0358	DNA primase activity
AW20_4006	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW20_4007	COG2010	Cytochrome c
AW20_4008	COG2384	SAM-dependent methyltransferase
AW20_4009	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW20_4015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_4016	COG1121	(ABC) transporter
AW20_4017	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW20_4018	COG0735	belongs to the Fur family
AW20_4023	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_4024	COG0477	Major facilitator Superfamily
AW20_4026	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW20_4027	COG0573	inorganic phosphate transmembrane transporter activity
AW20_4028	COG0581	inorganic phosphate transmembrane transporter activity
AW20_4030	COG0704	Plays a role in the regulation of phosphate uptake
AW20_4031	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW20_4032	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW20_4033	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW20_4034	COG4483	Protein conserved in bacteria
AW20_4035	COG1940	carbohydrate kinase activity
AW20_4037	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_4041	COG0626	cystathionine gamma-synthase activity
AW20_4042	COG0626	cystathionine gamma-synthase activity
AW20_4043	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW20_4043	COG0646	methionine synthase
AW20_4044	COG0646	methionine synthase
AW20_4044	COG1410	methionine synthase
AW20_4045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW20_4055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW20_4056	COG1459	type II secretion system
AW20_4058	COG4970	Tfp pilus assembly protein FimT
AW20_4069	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_4075	COG1725	Transcriptional regulator
AW20_4076	COG1131	(ABC) transporter
AW20_408	COG1247	-acetyltransferase
AW20_4083	COG2076	Multidrug Resistance protein
AW20_4084	COG2076	Multidrug Resistance protein
AW20_4086	COG1609	Transcriptional regulator
AW20_4087	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_4088	COG0095	Lipoate-protein ligase
AW20_4093	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW20_4094	COG3872	metal-dependent enzyme
AW20_4097	COG0006	proline dipeptidase activity
AW20_4102	COG3854	ATPases associated with a variety of cellular activities
AW20_4111	COG0511	ligase activity, forming carbon-carbon bonds
AW20_4112	COG0439	Biotin carboxylase
AW20_4113	COG1302	Protein conserved in bacteria
AW20_4118	COG0142	geranyltranstransferase activity
AW20_4120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW20_4122	COG0497	DNA recombination
AW20_4123	COG0750	zinc metalloprotease
AW20_4124	COG0745	RESPONSE REGULATOR receiver
AW20_4126	COG3093	addiction module antidote protein HigA
AW20_4127	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_4129	COG3290	protein histidine kinase activity
AW20_4129	COG3829	transcription factor binding
AW20_4130	COG0280	phosphate acetyltransferase
AW20_4133	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW20_4134	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_4135	COG0022	dehydrogenase e1 component
AW20_4136	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_4137	COG0772	Belongs to the SEDS family
AW20_4138	COG2816	NAD+ diphosphatase activity
AW20_4141	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_4142	COG0765	amino acid transport
AW20_4143	COG1126	abc transporter atp-binding protein
AW20_4144	COG4129	membrane
AW20_4145	COG1376	ErfK ybiS ycfS ynhG family protein
AW20_4147	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_4148	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW20_415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_4150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW20_4153	COG1760	l-serine dehydratase
AW20_4154	COG1760	l-serine dehydratase
AW20_4155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_4158	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_4159	COG0300	oxidoreductase activity
AW20_4162	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW20_4164	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW20_4168	COG1522	sequence-specific DNA binding
AW20_4170	COG0737	Belongs to the 5'-nucleotidase family
AW20_4173	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_4176	COG1073	alpha beta
AW20_4176	COG2226	methyltransferase
AW20_4177	COG4106	trans-aconitate 2-methyltransferase activity
AW20_4182	COG0307	riboflavin synthase, alpha
AW20_4183	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW20_4183	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW20_4186	COG1073	alpha beta
AW20_4187	COG0456	acetyltransferase
AW20_4188	COG1609	Transcriptional regulator
AW20_4189	COG2056	Na+-H+ antiporter family
AW20_4190	COG0596	Alpha beta hydrolase
AW20_4192	COG0737	Belongs to the 5'-nucleotidase family
AW20_4192	COG1525	nuclease
AW20_4192	COG4085	toxin activity
AW20_4194	COG0456	acetyltransferase
AW20_4194	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_4195	COG0656	L-ascorbic acid biosynthetic process
AW20_4196	COG0667	Aldo Keto reductase
AW20_4200	COG1300	Membrane
AW20_4201	COG0735	belongs to the Fur family
AW20_4203	COG4974	Belongs to the 'phage' integrase family
AW20_4208	COG0598	Magnesium transport protein CorA
AW20_4211	COG1846	Transcriptional regulator
AW20_4214	COG1131	(ABC) transporter
AW20_4215	COG1725	Transcriptional regulator
AW20_4216	COG1686	Belongs to the peptidase S11 family
AW20_4220	COG0733	neurotransmitter:sodium symporter activity
AW20_4225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_4228	COG0697	spore germination
AW20_4229	COG0561	phosphatase activity
AW20_4230	COG4086	secreted protein
AW20_4231	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW20_4232	COG0456	acetyltransferase
AW20_4233	COG1547	Domain of unknown function (DUF309)
AW20_4238	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW20_424	COG2226	methyltransferase
AW20_4240	COG2188	Transcriptional regulator
AW20_4242	COG3711	transcriptional antiterminator
AW20_4243	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_4243	COG1263	PTS System
AW20_4243	COG2190	(PTS) system
AW20_4249	COG0778	Nitroreductase
AW20_4250	COG3706	GGDEF domain
AW20_4255	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW20_4259	COG0436	Aminotransferase
AW20_4260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW20_4262	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW20_4264	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4265	COG1695	Transcriptional regulator
AW20_4272	COG0183	Belongs to the thiolase family
AW20_4280	COG3842	ATPase activity
AW20_4281	COG0366	Alpha amylase catalytic
AW20_4283	COG2182	Extracellular solute-binding protein
AW20_4284	COG1175	transmembrane transport
AW20_4285	COG3833	ABC-type maltose transport systems, permease component
AW20_4286	COG1609	Transcriptional regulator
AW20_4287	COG0436	Aminotransferase
AW20_4289	COG2205	protein histidine kinase activity
AW20_429	COG2814	Major facilitator Superfamily
AW20_4291	COG3209	COG3209 Rhs family protein
AW20_4295	COG2814	Major facilitator Superfamily
AW20_43	COG0517	IMP dehydrogenase activity
AW20_43	COG4175	Glycine betaine
AW20_430	COG0596	Alpha beta hydrolase
AW20_4302	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AW20_4304	COG1408	metallophosphoesterase
AW20_4305	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4306	COG2200	EAL domain
AW20_4309	COG4703	Protein of unknown function (DUF1797)
AW20_4311	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW20_4313	COG0517	IMP dehydrogenase activity
AW20_4314	COG0583	DNA-binding transcription factor activity
AW20_4318	COG0569	domain protein
AW20_4319	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_4321	COG0561	phosphatase activity
AW20_4322	COG0242	peptide deformylase activity
AW20_4324	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_4325	COG0022	dehydrogenase e1 component
AW20_4326	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_4335	COG1982	Orn Lys Arg decarboxylase major
AW20_4339	COG0483	inositol monophosphate 1-phosphatase activity
AW20_434	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_4344	COG4896	Protein conserved in bacteria
AW20_4346	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW20_4347	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW20_4349	COG0772	Belongs to the SEDS family
AW20_435	COG1187	pseudouridine synthase activity
AW20_4350	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW20_4357	COG3336	cytochrome c oxidase
AW20_436	COG2329	Antibiotic biosynthesis monooxygenase
AW20_4360	COG2340	Cysteine-rich secretory protein family
AW20_4363	COG0406	alpha-ribazole phosphatase activity
AW20_4364	COG3679	Belongs to the UPF0342 family
AW20_4368	COG0742	ribosomal rna small subunit methyltransferase
AW20_4369	COG3314	Sporulation integral membrane protein YlbJ
AW20_4371	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW20_4372	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW20_4374	COG0582	viral genome integration into host DNA
AW20_4378	COG1396	sequence-specific DNA binding
AW20_4382	COG1396	sequence-specific DNA binding
AW20_4388	COG1484	DNA-dependent DNA replication
AW20_439	COG1115	amino acid carrier protein
AW20_4393	COG1191	sigma factor activity
AW20_4396	COG0756	dUTP diphosphatase activity
AW20_44	COG4176	ABC-type proline glycine betaine transport system permease component
AW20_4408	COG0582	viral genome integration into host DNA
AW20_441	COG2318	DinB family
AW20_4413	COG4626	Terminase
AW20_4413	COG1802	Transcriptional regulator
AW20_443	COG0776	regulation of translation
AW20_4433	COG4824	toxin secretion phage lysis holin
AW20_4443	COG1399	metal-binding, possibly nucleic acid-binding protein
AW20_4444	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AW20_4447	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW20_4450	COG4839	cell division protein FtsL
AW20_4452	COG0768	penicillin binding
AW20_4453	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW20_4456	COG0772	Belongs to the SEDS family
AW20_4458	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW20_4459	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW20_446	COG2814	Major facilitator Superfamily
AW20_4460	COG0849	cell division
AW20_4461	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW20_4463	COG1191	sigma factor activity
AW20_4464	COG1191	sigma factor activity
AW20_4465	COG1873	PFAM PRC-barrel domain
AW20_4467	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW20_4469	COG0762	integral membrane protein
AW20_447	COG3251	PFAM MbtH domain protein
AW20_4470	COG2302	S4 RNA-binding domain
AW20_4471	COG3599	regulation of cell shape
AW20_4475	COG0564	pseudouridine synthase activity
AW20_448	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW20_4488	COG3069	C4-dicarboxylate transmembrane transporter activity
AW20_449	COG1535	isochorismatase
AW20_449	COG3433	isochorismatase activity
AW20_4491	COG0006	proline dipeptidase activity
AW20_4493	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW20_4494	COG1561	YicC-like family, N-terminal region
AW20_4498	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW20_4499	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW20_450	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW20_4500	COG0242	peptide deformylase activity
AW20_4502	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW20_4502	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW20_4504	COG0631	protein serine/threonine phosphatase activity
AW20_4505	COG0515	serine threonine protein kinase
AW20_4505	COG2815	serine threonine protein kinase
AW20_4506	COG1162	GTPase activity
AW20_4507	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW20_4508	COG1564	THIamine pyrophosphokinase
AW20_451	COG1169	isochorismate synthase
AW20_4510	COG1302	Protein conserved in bacteria
AW20_4511	COG1461	Dihydroxyacetone kinase
AW20_4512	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW20_4515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW20_4516	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4517	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW20_4519	COG1196	nuclear chromosome segregation
AW20_452	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4520	COG0552	protein localization to endoplasmic reticulum
AW20_4522	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW20_4524	COG1837	Belongs to the UPF0109 family
AW20_453	COG2223	nitrite transmembrane transporter activity
AW20_4532	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW20_4534	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW20_4536	COG4974	Belongs to the 'phage' integrase family
AW20_4542	COG0528	UMP kinase activity
AW20_4544	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW20_4545	COG4589	Belongs to the CDS family
AW20_4547	COG0750	zinc metalloprotease
AW20_4551	COG0195	Participates in both transcription termination and antitermination
AW20_4552	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW20_4553	COG1358	cellular component organization or biogenesis
AW20_4555	COG1550	Protein conserved in bacteria
AW20_4557	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW20_4558	COG0196	riboflavin kinase activity
AW20_4561	COG0726	polysaccharide deacetylase
AW20_4562	COG0612	Peptidase, M16
AW20_4563	COG1873	PFAM PRC-barrel domain
AW20_4564	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW20_4565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW20_4566	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW20_4567	COG0527	aspartate kinase activity
AW20_4569	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_457	COG0419	ATPase involved in DNA repair
AW20_4570	COG0740	serine-type endopeptidase activity
AW20_4572	COG1674	ftsk spoiiie
AW20_4573	COG2188	Transcriptional regulator
AW20_4579	COG0612	Peptidase, M16
AW20_458	COG0420	3'-5' exonuclease activity
AW20_4580	COG0612	Peptidase, M16
AW20_4581	COG0300	oxidoreductase activity
AW20_4584	COG1426	Protein conserved in bacteria
AW20_4585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW20_4590	COG1692	metallophosphoesterase
AW20_4591	COG2359	stage V sporulation protein S
AW20_4593	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW20_4593	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW20_4594	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW20_4595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW20_4596	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW20_4600	COG1131	(ABC) transporter
AW20_4605	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW20_4607	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_4608	COG1368	sulfuric ester hydrolase activity
AW20_4609	COG0562	UDP-galactopyranose mutase
AW20_461	COG1024	Enoyl-CoA hydratase
AW20_4610	COG3773	Cell wall hydrolase
AW20_4611	COG1404	Belongs to the peptidase S8 family
AW20_4614	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_4615	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_4615	COG0596	Alpha beta hydrolase
AW20_4616	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_4617	COG1380	Effector of murein hydrolase LrgA
AW20_4618	COG1346	cytolysis
AW20_462	COG1280	lysine exporter protein (LysE YggA)
AW20_4621	COG3300	MHYT domain
AW20_4621	COG5001	Diguanylate cyclase
AW20_4622	COG0346	lactoylglutathione lyase activity
AW20_4623	COG2267	carboxylic ester hydrolase activity
AW20_4626	COG2364	Membrane
AW20_4628	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW20_4629	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW20_4630	COG2169	Transcriptional regulator
AW20_4631	COG0708	Exodeoxyribonuclease III
AW20_4633	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_4634	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_4635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_4636	COG1120	ATPase activity
AW20_4637	COG2819	hydrolase of the alpha beta superfamily
AW20_4639	COG1937	Protein conserved in bacteria
AW20_464	COG2084	Dehydrogenase
AW20_4640	COG2608	mercury ion transmembrane transporter activity
AW20_4641	COG2217	Heavy metal translocating P-type atpase
AW20_4643	COG2116	formate transmembrane transporter activity
AW20_4644	COG1408	metallophosphoesterase
AW20_4647	COG1113	amino acid transport
AW20_465	COG1960	acyl-CoA dehydrogenase activity
AW20_4650	COG2322	membrane
AW20_4651	COG1979	alcohol dehydrogenase
AW20_4652	COG1979	alcohol dehydrogenase
AW20_4653	COG1349	DNA-binding transcription factor activity
AW20_4654	COG1105	Belongs to the carbohydrate kinase PfkB family
AW20_4655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW20_4655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW20_4655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_4656	COG3584	3D domain protein
AW20_4656	COG1388	LysM domain
AW20_466	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW20_4663	COG0464	growth
AW20_4664	COG2860	membrane
AW20_4665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW20_4666	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW20_4667	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW20_4668	COG0789	Transcriptional regulator
AW20_4669	COG0174	glutamine synthetase
AW20_467	COG2079	MmgE PrpD family protein
AW20_4674	COG1396	sequence-specific DNA binding
AW20_468	COG0372	Belongs to the citrate synthase family
AW20_469	COG4841	protein insertion into membrane
AW20_4690	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AW20_4698	COG1595	DNA-templated transcription, initiation
AW20_470	COG2814	Major facilitator Superfamily
AW20_471	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW20_471	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_4730	COG4824	toxin secretion phage lysis holin
AW20_4731	COG1388	LysM domain
AW20_4731	COG3409	Peptidoglycan-binding domain 1 protein
AW20_4731	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_4739	COG1695	Transcriptional regulator
AW20_4743	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW20_4745	COG0737	Belongs to the 5'-nucleotidase family
AW20_4748	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AW20_4749	COG3639	organic phosphonate transmembrane transporter activity
AW20_4755	COG1132	(ABC) transporter
AW20_4756	COG1132	(ABC) transporter
AW20_4759	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_4759	COG3409	Peptidoglycan-binding domain 1 protein
AW20_4761	COG0730	response to heat
AW20_4764	COG1346	cytolysis
AW20_4765	COG1380	Effector of murein hydrolase LrgA
AW20_4766	COG0583	DNA-binding transcription factor activity
AW20_4768	COG0785	Cytochrome C biogenesis protein
AW20_4769	COG4846	Membrane protein involved in cytochrome C biogenesis
AW20_4779	COG2226	methyltransferase
AW20_4784	COG0010	Belongs to the arginase family
AW20_4785	COG1329	Transcriptional regulator
AW20_4786	COG1902	pentaerythritol trinitrate reductase activity
AW20_4787	COG0069	glutamate synthase activity
AW20_4788	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_4789	COG0346	lactoylglutathione lyase activity
AW20_479	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_4790	COG0400	carboxylic ester hydrolase activity
AW20_4791	COG5002	protein histidine kinase activity
AW20_4793	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_4802	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_4803	COG1268	BioY protein
AW20_4804	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_4805	COG0183	Belongs to the thiolase family
AW20_4808	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_4810	COG2211	Major facilitator Superfamily
AW20_4815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW20_4816	COG2274	protein secretion by the type I secretion system
AW20_4818	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_4824	COG0824	Thioesterase
AW20_4825	COG4841	protein insertion into membrane
AW20_4826	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_4829	COG0745	RESPONSE REGULATOR receiver
AW20_4830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_4831	COG1832	CoA-binding protein
AW20_4832	COG0187	DNA topoisomerase II activity
AW20_4833	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW20_4834	COG0673	inositol 2-dehydrogenase activity
AW20_4836	COG1131	(ABC) transporter
AW20_4840	COG1595	DNA-templated transcription, initiation
AW20_4842	COG1316	TRANSCRIPTIONal
AW20_4843	COG1301	dicarboxylic acid transport
AW20_4844	COG4166	transmembrane transport
AW20_4845	COG4166	transmembrane transport
AW20_4846	COG4166	transmembrane transport
AW20_4847	COG2226	methyltransferase
AW20_4855	COG0697	spore germination
AW20_4857	COG3383	formate dehydrogenase (NAD+) activity
AW20_4858	COG2427	Protein of unknown function (DUF1641)
AW20_4859	COG5609	conserved protein (DUF2294)
AW20_4860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW20_4862	COG2116	formate transmembrane transporter activity
AW20_4863	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_4864	COG0303	'Molybdopterin
AW20_4865	COG0314	molybdopterin synthase activity
AW20_4867	COG0489	protein tyrosine kinase activity
AW20_4870	COG3326	Membrane
AW20_4871	COG2962	Rard protein
AW20_4872	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW20_4873	COG1657	PFAM Prenyltransferase squalene oxidase
AW20_4875	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4876	COG1012	belongs to the aldehyde dehydrogenase family
AW20_4878	COG4145	pantothenate transmembrane transporter activity
AW20_4881	COG0165	Argininosuccinate lyase
AW20_4883	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_4889	COG0716	FMN binding
AW20_4897	COG2720	vancomycin resistance protein
AW20_4898	COG2514	catechol 2,3-dioxygenase activity
AW20_4900	COG1285	pathogenesis
AW20_4902	COG1024	Enoyl-CoA hydratase
AW20_4903	COG1216	Glycosyl transferase, family 2
AW20_4909	COG0277	FAD linked oxidase domain protein
AW20_4910	COG0385	Bile acid
AW20_4912	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_4913	COG2808	Putative FMN-binding domain
AW20_4916	COG0457	Tetratricopeptide repeat
AW20_4918	COG0604	alcohol dehydrogenase
AW20_4919	COG0640	Transcriptional regulator
AW20_4923	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_4929	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_4930	COG1164	Oligoendopeptidase f
AW20_4931	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW20_4934	COG1193	negative regulation of DNA recombination
AW20_4938	COG0583	DNA-binding transcription factor activity
AW20_4944	COG0384	phenazine biosynthesis protein PhzF
AW20_4945	COG3739	integral membrane protein
AW20_4946	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_4947	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_4949	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_495	COG1787	Restriction endonuclease
AW20_495	COG1715	Restriction endonuclease
AW20_4953	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_4954	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_4960	COG2814	Major facilitator Superfamily
AW20_4961	COG1113	amino acid transport
AW20_4962	COG0604	alcohol dehydrogenase
AW20_4963	COG0604	alcohol dehydrogenase
AW20_4970	COG2072	flavoprotein involved in K transport
AW20_4977	COG3409	Peptidoglycan-binding domain 1 protein
AW20_4977	COG3757	hydrolase, family 25
AW20_4978	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_4981	COG1151	hydroxylamine reductase activity
AW20_4986	COG3152	Membrane
AW20_4990	COG1309	transcriptional regulator
AW20_4993	COG1191	sigma factor activity
AW20_50	COG0456	acetyltransferase
AW20_50	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_5000	COG1733	regulation of RNA biosynthetic process
AW20_5001	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_5003	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_5005	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_5007	COG0384	phenazine biosynthesis protein PhzF
AW20_501	COG0671	phosphoesterase, PA-phosphatase related
AW20_5011	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_5014	COG1733	regulation of RNA biosynthetic process
AW20_5015	COG1733	regulation of RNA biosynthetic process
AW20_5016	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW20_5018	COG0673	inositol 2-dehydrogenase activity
AW20_5019	COG2188	Transcriptional regulator
AW20_502	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW20_5020	COG1733	regulation of RNA biosynthetic process
AW20_5021	COG1393	Belongs to the ArsC family
AW20_5026	COG0814	amino acid
AW20_5027	COG0346	lactoylglutathione lyase activity
AW20_503	COG4326	sporulation control protein
AW20_5030	COG2814	Major facilitator Superfamily
AW20_5031	COG0656	L-ascorbic acid biosynthetic process
AW20_5036	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_5039	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_5040	COG0604	alcohol dehydrogenase
AW20_5041	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW20_5042	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW20_5044	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW20_5045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW20_5047	COG1070	Carbohydrate kinase
AW20_5048	COG2706	6-phosphogluconolactonase activity
AW20_5049	COG3813	Protein conserved in bacteria
AW20_5050	COG1357	PFAM Pentapeptide repeats (8 copies)
AW20_5051	COG0697	spore germination
AW20_5052	COG0789	Transcriptional regulator
AW20_5053	COG1253	flavin adenine dinucleotide binding
AW20_5059	COG0477	Major facilitator Superfamily
AW20_5061	COG2226	methyltransferase
AW20_5065	COG0628	permease
AW20_5066	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW20_5069	COG0577	efflux transmembrane transporter activity
AW20_5069	COG1136	(ABC) transporter
AW20_5072	COG0110	maltose O-acetyltransferase activity
AW20_5073	COG0738	Major facilitator superfamily
AW20_5074	COG1940	carbohydrate kinase activity
AW20_5075	COG0346	lactoylglutathione lyase activity
AW20_5082	COG1011	Hydrolase
AW20_5087	COG1131	(ABC) transporter
AW20_5089	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_5093	COG0778	Nitroreductase
AW20_5094	COG1733	regulation of RNA biosynthetic process
AW20_5097	COG0124	histidyl-tRNA synthetase
AW20_5098	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW20_5099	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_51	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_5100	COG3620	sequence-specific DNA binding
AW20_5103	COG2356	endonuclease I
AW20_5104	COG1288	antiporter activity
AW20_5105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AW20_5108	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW20_5109	COG1122	ATPase activity
AW20_511	COG1509	lysine 2,3-aminomutase activity
AW20_5115	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_5117	COG2031	fatty acid transporter
AW20_5119	COG1309	transcriptional regulator
AW20_512	COG3829	transcription factor binding
AW20_5120	COG2076	Multidrug Resistance protein
AW20_5124	COG1131	(ABC) transporter
AW20_5125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_5128	COG2814	Major facilitator Superfamily
AW20_5129	COG1846	Transcriptional regulator
AW20_513	COG0456	acetyltransferase
AW20_5131	COG0477	Major facilitator Superfamily
AW20_514	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_5142	COG2207	Transcriptional regulator
AW20_5142	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_5143	COG0662	Cupin 2, conserved barrel domain protein
AW20_5146	COG1595	DNA-templated transcription, initiation
AW20_515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW20_5150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW20_5154	COG0531	amino acid
AW20_5155	COG1522	sequence-specific DNA binding
AW20_5156	COG1335	isochorismatase
AW20_5158	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW20_5159	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW20_516	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW20_5160	COG1760	l-serine dehydratase
AW20_5161	COG1760	l-serine dehydratase
AW20_5162	COG0814	amino acid
AW20_5165	COG1309	transcriptional regulator
AW20_5166	COG2814	Major facilitator Superfamily
AW20_5167	COG2184	nucleotidyltransferase activity
AW20_517	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_5170	COG0534	Mate efflux family protein
AW20_5177	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW20_5181	COG0457	Tetratricopeptide repeat
AW20_5182	COG1609	Transcriptional regulator
AW20_5183	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW20_5184	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW20_5185	COG0561	phosphatase activity
AW20_5186	COG0673	inositol 2-dehydrogenase activity
AW20_5187	COG0738	Major facilitator superfamily
AW20_5191	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_5193	COG0583	DNA-binding transcription factor activity
AW20_5195	COG1139	Iron-sulfur cluster binding protein
AW20_5196	COG1556	Lactate utilization protein
AW20_5197	COG2271	Major facilitator Superfamily
AW20_5198	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_5199	COG2808	Putative FMN-binding domain
AW20_520	COG5506	Protein of unknown function (DUF1694)
AW20_5200	COG0456	acetyltransferase
AW20_5201	COG1846	Transcriptional regulator
AW20_5202	COG2364	Membrane
AW20_5204	COG3850	Histidine kinase
AW20_5204	COG5002	protein histidine kinase activity
AW20_5207	COG0577	efflux transmembrane transporter activity
AW20_5208	COG1136	(ABC) transporter
AW20_521	COG1012	belongs to the aldehyde dehydrogenase family
AW20_5211	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW20_5212	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_5214	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW20_5215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_5218	COG1476	TRANSCRIPTIONal
AW20_522	COG1253	flavin adenine dinucleotide binding
AW20_5224	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AW20_5229	COG3850	Histidine kinase
AW20_5229	COG5002	protein histidine kinase activity
AW20_5230	COG0745	RESPONSE REGULATOR receiver
AW20_5235	COG2814	Major facilitator Superfamily
AW20_5247	COG0346	lactoylglutathione lyase activity
AW20_5250	COG1522	sequence-specific DNA binding
AW20_5253	COG0443	Heat shock 70 kDa protein
AW20_5257	COG0640	Transcriptional regulator
AW20_5258	COG0346	lactoylglutathione lyase activity
AW20_5259	COG0798	PFAM Bile acid sodium symporter
AW20_5265	COG1121	(ABC) transporter
AW20_5266	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW20_5267	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW20_5268	COG2267	carboxylic ester hydrolase activity
AW20_5269	COG1575	Belongs to the MenA family. Type 1 subfamily
AW20_5271	COG5609	conserved protein (DUF2294)
AW20_5272	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW20_5274	COG0288	reversible hydration of carbon dioxide
AW20_5275	COG0415	Belongs to the DNA photolyase family
AW20_5282	COG0598	Magnesium transport protein CorA
AW20_5283	COG0598	Magnesium transport protein CorA
AW20_5284	COG1846	Transcriptional regulator
AW20_5285	COG0583	DNA-binding transcription factor activity
AW20_529	COG1174	glycine betaine transport
AW20_5290	COG1335	isochorismatase
AW20_5291	COG2267	carboxylic ester hydrolase activity
AW20_5292	COG0753	catalase activity
AW20_5293	COG0737	Belongs to the 5'-nucleotidase family
AW20_53	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_530	COG1125	glycine betaine transport
AW20_530	COG0517	IMP dehydrogenase activity
AW20_5302	COG2066	Belongs to the glutaminase family
AW20_5303	COG4191	Histidine kinase
AW20_5304	COG4191	Histidine kinase
AW20_5305	COG0784	Response regulator, receiver
AW20_5306	COG0697	spore germination
AW20_5307	COG0531	amino acid
AW20_5312	COG0281	malic enzyme
AW20_5314	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_5315	COG1114	Component of the transport system for branched-chain amino acids
AW20_5316	COG0531	amino acid
AW20_5317	COG0322	excinuclease ABC activity
AW20_5319	COG1396	sequence-specific DNA binding
AW20_5320	COG0252	asparaginase activity
AW20_5321	COG1027	Aspartate ammonia-lyase
AW20_5324	COG1063	alcohol dehydrogenase
AW20_5330	COG1113	amino acid transport
AW20_5331	COG1113	amino acid transport
AW20_5332	COG1280	lysine exporter protein (LysE YggA)
AW20_5333	COG3403	YqcI/YcgG family
AW20_5335	COG5577	PFAM Coat F domain
AW20_5338	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_5339	COG3848	Pyruvate phosphate dikinase
AW20_5339	COG0574	Belongs to the PEP-utilizing enzyme family
AW20_5342	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW20_5349	COG1960	acyl-CoA dehydrogenase activity
AW20_5351	COG0640	Transcriptional regulator
AW20_5352	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_5355	COG1414	Transcriptional regulator
AW20_5356	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW20_5357	COG1984	allophanate hydrolase subunit 2
AW20_536	COG1070	Carbohydrate kinase
AW20_5364	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW20_537	COG1070	Carbohydrate kinase
AW20_5374	COG4335	DNA alkylation repair
AW20_5376	COG0833	amino acid
AW20_5378	COG0730	response to heat
AW20_5384	COG0596	Alpha beta hydrolase
AW20_5385	COG0745	RESPONSE REGULATOR receiver
AW20_5386	COG0642	Histidine kinase
AW20_5390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_5394	COG0456	acetyltransferase
AW20_5395	COG2207	Transcriptional regulator
AW20_54	COG0022	dehydrogenase e1 component
AW20_5401	COG0577	efflux transmembrane transporter activity
AW20_5401	COG1136	(ABC) transporter
AW20_5403	COG1725	Transcriptional regulator
AW20_5410	COG1846	Transcriptional regulator
AW20_5411	COG0778	Nitroreductase
AW20_5413	COG0714	Associated with various cellular activities
AW20_5419	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW20_5421	COG0753	catalase activity
AW20_5422	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW20_5424	COG0463	Glycosyl transferase, family 2
AW20_5429	COG0463	Glycosyl transferase, family 2
AW20_5434	COG0714	Associated with various cellular activities
AW20_5438	COG0346	lactoylglutathione lyase activity
AW20_5439	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_544	COG1064	alcohol dehydrogenase
AW20_5441	COG3279	Response regulator of the LytR AlgR family
AW20_5443	COG4377	Putative membrane peptidase family (DUF2324)
AW20_5446	COG3655	Transcriptional regulator
AW20_5448	COG1785	Belongs to the alkaline phosphatase family
AW20_5449	COG3239	Fatty acid desaturase
AW20_545	COG1737	Transcriptional regulator
AW20_5450	COG1690	Belongs to the RtcB family
AW20_5451	COG0833	amino acid
AW20_5452	COG1414	Transcriptional regulator
AW20_5453	COG4187	Peptidase family M20/M25/M40
AW20_5454	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_5455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW20_5457	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_5461	COG2329	Antibiotic biosynthesis monooxygenase
AW20_5469	COG1070	Carbohydrate kinase
AW20_547	COG2197	response regulator
AW20_5470	COG2390	Transcriptional regulator
AW20_5472	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW20_5474	COG1879	ABC-type sugar transport system periplasmic component
AW20_548	COG4585	Histidine kinase
AW20_548	COG2203	Gaf domain
AW20_5480	COG1595	DNA-templated transcription, initiation
AW20_5482	COG3584	3D domain protein
AW20_5482	COG1388	LysM domain
AW20_549	COG0668	transmembrane transport
AW20_5490	COG1605	Chorismate mutase
AW20_5490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW20_5491	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW20_5492	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW20_5493	COG0287	Prephenate dehydrogenase
AW20_5496	COG1309	transcriptional regulator
AW20_5497	COG1033	growth of symbiont in host cell
AW20_5497	COG2409	Drug exporters of the RND superfamily
AW20_5498	COG1033	growth of symbiont in host cell
AW20_5498	COG2409	Drug exporters of the RND superfamily
AW20_55	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_5500	COG0488	(ABC) transporter
AW20_5501	COG1368	sulfuric ester hydrolase activity
AW20_5502	COG0861	Integral membrane protein TerC family
AW20_5506	COG4912	Dna alkylation repair
AW20_551	COG1051	belongs to the nudix hydrolase family
AW20_5510	COG2318	DinB family
AW20_5511	COG0697	spore germination
AW20_5516	COG2746	aminoglycoside 3-N-acetyltransferase activity
AW20_552	COG1335	isochorismatase
AW20_5524	COG1116	anion transmembrane transporter activity
AW20_5525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_5526	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_5527	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_5529	COG0628	permease
AW20_5538	COG1131	(ABC) transporter
AW20_5543	COG5146	pantothenate kinase activity
AW20_5544	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW20_5545	COG0436	Aminotransferase
AW20_5552	COG2226	methyltransferase
AW20_5555	COG2261	transglycosylase associated protein
AW20_5559	COG0477	Major facilitator Superfamily
AW20_5559	COG2814	Major facilitator Superfamily
AW20_556	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_5560	COG4533	DNA binding
AW20_5561	COG0789	Transcriptional regulator
AW20_5562	COG1664	Polymer-forming cytoskeletal
AW20_5564	COG2814	Major facilitator Superfamily
AW20_5568	COG1307	EDD domain protein, DegV family
AW20_557	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_5571	COG1164	Oligoendopeptidase f
AW20_5578	COG0745	RESPONSE REGULATOR receiver
AW20_5579	COG5002	protein histidine kinase activity
AW20_5580	COG2936	dipeptidyl-peptidase activity
AW20_5588	COG4948	Mandelate Racemase Muconate Lactonizing
AW20_5590	COG4166	transmembrane transport
AW20_5591	COG0519	Catalyzes the synthesis of GMP from XMP
AW20_5592	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW20_5595	COG0586	Pfam SNARE associated Golgi protein
AW20_56	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW20_5602	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_5603	COG3938	Belongs to the proline racemase family
AW20_5605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW20_5606	COG1012	belongs to the aldehyde dehydrogenase family
AW20_561	COG0367	asparagine synthase
AW20_5612	COG0457	Tetratricopeptide repeat
AW20_5617	COG4974	Belongs to the 'phage' integrase family
AW20_5619	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW20_562	COG0071	Belongs to the small heat shock protein (HSP20) family
AW20_5621	COG2801	Transposase and inactivated derivatives
AW20_5622	COG2801	Transposase and inactivated derivatives
AW20_5625	COG2801	Transposase and inactivated derivatives
AW20_5626	COG2801	Transposase and inactivated derivatives
AW20_563	COG1999	signal sequence binding
AW20_5635	COG4974	Belongs to the 'phage' integrase family
AW20_5637	COG2002	toxin-antitoxin pair type II binding
AW20_564	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW20_565	COG1307	EDD domain protein, DegV family
AW20_567	COG0805	protein transport
AW20_5673	COG2801	Transposase and inactivated derivatives
AW20_5674	COG2801	Transposase and inactivated derivatives
AW20_5678	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW20_5679	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW20_5680	COG1215	transferase activity, transferring glycosyl groups
AW20_5682	COG0671	phosphoesterase, PA-phosphatase related
AW20_5683	COG4196	transglutaminase domain protein
AW20_5689	COG2311	Membrane
AW20_569	COG1272	protein, Hemolysin III
AW20_570	COG0204	Acyl-transferase
AW20_571	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_5719	COG4962	Type ii secretion system protein e
AW20_572	COG0768	penicillin binding
AW20_575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_5765	COG3344	reverse transcriptase
AW20_5786	COG3344	reverse transcriptase
AW20_579	COG0546	phosphoglycolate phosphatase activity
AW20_581	COG4473	ABC transporter
AW20_582	COG1131	(ABC) transporter
AW20_584	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AW20_586	COG0456	acetyltransferase
AW20_588	COG1794	racemase activity, acting on amino acids and derivatives
AW20_589	COG1454	alcohol dehydrogenase
AW20_590	COG2610	gluconate transmembrane transporter activity
AW20_595	COG0733	neurotransmitter:sodium symporter activity
AW20_598	COG5002	protein histidine kinase activity
AW20_598	COG3850	Histidine kinase
AW20_599	COG0745	RESPONSE REGULATOR receiver
AW20_60	COG1959	2 iron, 2 sulfur cluster binding
AW20_600	COG0471	metal ion transport
AW20_601	COG1929	Belongs to the glycerate kinase type-1 family
AW20_620	COG1674	ftsk spoiiie
AW20_624	COG0017	Asparaginyl-tRNA synthetase
AW20_625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW20_628	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW20_634	COG0018	arginyl-trna synthetase
AW20_635	COG2521	methyltransferase
AW20_635	COG2136	Putative SAM-dependent methyltransferase
AW20_638	COG1413	lyase activity
AW20_639	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW20_64	COG1349	DNA-binding transcription factor activity
AW20_642	COG0629	single-stranded DNA binding
AW20_645	COG0488	(ABC) transporter
AW20_646	COG1418	mRNA catabolic process
AW20_649	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_652	COG2359	stage V sporulation protein S
AW20_659	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AW20_660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW20_661	COG2146	nitrite reductase [NAD(P)H] activity
AW20_662	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW20_662	COG1587	Uroporphyrinogen-III synthase
AW20_664	COG1648	precorrin-2 dehydrogenase activity
AW20_667	COG2223	nitrite transmembrane transporter activity
AW20_669	COG0314	molybdopterin synthase activity
AW20_670	COG0303	'Molybdopterin
AW20_671	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_672	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW20_673	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW20_677	COG2181	nitrate reductase activity
AW20_678	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW20_679	COG1140	nitrate reductase beta subunit
AW20_68	COG3284	Transcriptional regulator
AW20_680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW20_683	COG0714	Associated with various cellular activities
AW20_684	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW20_685	COG1305	Transglutaminase-like
AW20_686	COG0386	Belongs to the glutathione peroxidase family
AW20_691	COG1595	DNA-templated transcription, initiation
AW20_692	COG0604	alcohol dehydrogenase
AW20_694	COG0346	lactoylglutathione lyase activity
AW20_695	COG1082	Xylose isomerase domain protein TIM barrel
AW20_699	COG2226	methyltransferase
AW20_704	COG3874	Sporulation protein YtfJ
AW20_713	COG0456	acetyltransferase
AW20_719	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_721	COG1819	glycosyl
AW20_724	COG4106	trans-aconitate 2-methyltransferase activity
AW20_725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW20_727	COG0561	phosphatase activity
AW20_731	COG2211	Major facilitator Superfamily
AW20_732	COG0154	amidase activity
AW20_734	COG1876	peptidase activity
AW20_736	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_74	COG1309	transcriptional regulator
AW20_740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_741	COG1114	Component of the transport system for branched-chain amino acids
AW20_744	COG1253	flavin adenine dinucleotide binding
AW20_745	COG2839	Protein conserved in bacteria
AW20_746	COG0702	epimerase
AW20_749	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_75	COG3844	kynureninase activity
AW20_751	COG1607	acyl-coa hydrolase
AW20_752	COG3689	TIGRFAM TIGR03943 family protein
AW20_753	COG0701	Predicted permease
AW20_755	COG2244	polysaccharide biosynthetic process
AW20_756	COG0586	Pfam SNARE associated Golgi protein
AW20_757	COG1051	belongs to the nudix hydrolase family
AW20_758	COG5337	Spore coat protein CotH
AW20_76	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AW20_760	COG0406	alpha-ribazole phosphatase activity
AW20_763	COG4166	transmembrane transport
AW20_765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW20_767	COG0702	epimerase
AW20_769	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW20_769	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW20_77	COG3483	tryptophan 2,3-dioxygenase activity
AW20_780	COG0456	acetyltransferase
AW20_781	COG0523	cobalamin synthesis protein
AW20_782	COG4989	oxidoreductase activity
AW20_784	COG1231	oxidoreductase activity
AW20_786	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_789	COG0783	Belongs to the Dps family
AW20_790	COG3949	Membrane
AW20_793	COG0840	transmembrane signaling receptor activity
AW20_798	COG2814	Major facilitator Superfamily
AW20_799	COG0667	Aldo Keto reductase
AW20_800	COG0640	Transcriptional regulator
AW20_801	COG1404	Belongs to the peptidase S8 family
AW20_802	COG2002	toxin-antitoxin pair type II binding
AW20_803	COG0577	efflux transmembrane transporter activity
AW20_804	COG0577	efflux transmembrane transporter activity
AW20_81	COG2959	enzyme of heme biosynthesis
AW20_811	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW20_813	COG1279	arginine transmembrane transporter activity
AW20_814	COG2814	Major facilitator Superfamily
AW20_815	COG2814	Major facilitator Superfamily
AW20_816	COG2814	Major facilitator Superfamily
AW20_818	COG1082	Xylose isomerase domain protein TIM barrel
AW20_821	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_822	COG4264	IucA IucC family
AW20_824	COG1247	-acetyltransferase
AW20_825	COG1285	pathogenesis
AW20_828	COG5002	protein histidine kinase activity
AW20_829	COG0745	RESPONSE REGULATOR receiver
AW20_831	COG1316	TRANSCRIPTIONal
AW20_836	COG0460	homoserine dehydrogenase
AW20_84	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_842	COG0300	oxidoreductase activity
AW20_844	COG5002	protein histidine kinase activity
AW20_845	COG0745	RESPONSE REGULATOR receiver
AW20_846	COG1132	(ABC) transporter
AW20_847	COG1132	(ABC) transporter
AW20_849	COG0791	NLP P60 protein
AW20_849	COG1388	LysM domain
AW20_85	COG4129	membrane
AW20_851	COG1686	Belongs to the peptidase S11 family
AW20_855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW20_856	COG4988	ABC transporter
AW20_857	COG1294	oxidase, subunit
AW20_858	COG1271	oxidase subunit
AW20_860	COG1846	Transcriptional regulator
AW20_862	COG1942	4-Oxalocrotonate Tautomerase
AW20_864	COG0583	DNA-binding transcription factor activity
AW20_868	COG0411	ABC transporter
AW20_870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_871	COG2030	dehydratase
AW20_872	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_875	COG0523	cobalamin synthesis protein
AW20_876	COG1231	oxidoreductase activity
AW20_878	COG0628	permease
AW20_881	COG0778	Nitroreductase
AW20_882	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW20_883	COG1959	2 iron, 2 sulfur cluster binding
AW20_884	COG0583	DNA-binding transcription factor activity
AW20_885	COG0697	spore germination
AW20_887	COG4549	nuclear export factor GLE1
AW20_888	COG2372	response to copper ion
AW20_888	COG1276	copper resistance
AW20_890	COG1114	Component of the transport system for branched-chain amino acids
AW20_891	COG1114	Component of the transport system for branched-chain amino acids
AW20_892	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_898	COG2132	Multicopper oxidase
AW20_899	COG0006	proline dipeptidase activity
AW20_9	COG4637	Psort location Cytoplasmic, score
AW20_903	COG4224	UPF0291 protein
AW20_905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW20_906	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_908	COG2390	Transcriptional regulator
AW20_91	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_913	COG0531	amino acid
AW20_914	COG0531	amino acid
AW20_916	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW20_919	COG1914	H( )-stimulated, divalent metal cation uptake system
AW20_92	COG0697	spore germination
AW20_924	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_930	COG4166	transmembrane transport
AW20_931	COG1073	alpha beta
AW20_935	COG0427	acetyl-CoA hydrolase
AW20_936	COG3279	Response regulator of the LytR AlgR family
AW20_938	COG3384	dioxygenase
AW20_939	COG2814	Major facilitator Superfamily
AW20_94	COG0201	protein transport
AW20_944	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW20_946	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW20_947	COG0440	acetolactate synthase activity
AW20_948	COG0028	Belongs to the TPP enzyme family
AW20_949	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_951	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_955	COG2084	Dehydrogenase
AW20_958	COG2323	membrane
AW20_959	COG5566	PFAM Mor transcription activator
AW20_961	COG0733	neurotransmitter:sodium symporter activity
AW20_962	COG2244	polysaccharide biosynthetic process
AW20_965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_966	COG2223	nitrite transmembrane transporter activity
AW20_967	COG4166	transmembrane transport
AW20_969	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW20_971	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_972	COG0477	Major facilitator Superfamily
AW20_973	COG0477	Major facilitator Superfamily
AW20_975	COG1966	Carbon starvation protein
AW20_978	COG2814	Major facilitator Superfamily
AW20_98	COG3227	Zinc metalloprotease (Elastase)
AW20_980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_981	COG1051	belongs to the nudix hydrolase family
AW20_99	COG1523	belongs to the glycosyl hydrolase 13 family
AW20_992	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_993	COG0784	Response regulator, receiver
AW20_994	COG4191	Histidine kinase
AW20_995	COG0281	malic enzyme
AW20_996	COG1027	Aspartate ammonia-lyase
AW20_998	COG0528	UMP kinase activity
AW20_999	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol