locus-tag class description DJ46_1 ENOG4105CAQ asparagine synthetase DJ46_10 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ46_1006 ENOG4105BZW Glycerate kinase DJ46_1007 ENOG4107QPK )-transporter DJ46_1008 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_1009 ENOG41062D9 Histidine kinase DJ46_101 ENOG4105VZ8 Transcriptional regulator DJ46_1012 ENOG4105C8J )-transporter DJ46_1018 ENOG4105CY2 Citrate transporter DJ46_1019 ENOG4105C0A alcohol dehydrogenase DJ46_1022 ENOG4105KD7 acetyltransferase DJ46_1024 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase DJ46_1029 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 DJ46_1033 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) DJ46_1036 ENOG4107RVG penicillin-binding protein DJ46_1037 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DJ46_1038 ENOG4105E9Q Acyl-transferase DJ46_1039 ENOG4108UT2 hemolysin iii DJ46_1041 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DJ46_1043 ENOG4108RCR degv family DJ46_1044 ENOG4105E8R UPF0173 metal-dependent hydrolase DJ46_1045 ENOG4108KF3 Electron transport protein SCO1 SenC DJ46_1046 ENOG4107Y70 Heat shock protein DJ46_1047 ENOG4105CAQ asparagine synthetase DJ46_1051 ENOG4108MES Periplasmic binding protein DJ46_1052 ENOG4105F0I Aminotransferase DJ46_1059 ENOG4105D8X mechanosensitive ion channel DJ46_1060 ENOG4105BZU Histidine kinase DJ46_1061 ENOG4105WH1 Two component transcriptional regulator luxr family DJ46_1063 ENOG4106KNT transcriptional regulator DJ46_1071 ENOG4105CMG Carbohydrate kinase DJ46_1072 ENOG4105CMG Carbohydrate kinase DJ46_1078 ENOG4108IJ8 ABC transporter DJ46_1079 ENOG4105E90 ABC transporter DJ46_1086 ENOG4105C37 (CBS) domain DJ46_1091 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ46_1094 ENOG4107S4Y M20 DapE family protein YgeY DJ46_1095 ENOG4108TSC N-acetyltransferase DJ46_1096 ENOG4108JUB Transcriptional regulator DJ46_1097 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DJ46_1105 ENOG4108N23 SpoOM-related protein DJ46_1107 ENOG410841Q phosphoesterase PA-phosphatase related protein DJ46_1108 ENOG4105SZ6 Thioredoxin DJ46_1110 ENOG4108IBT Inherit from COG: transposase DJ46_112 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) DJ46_1129 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ46_1139 ENOG4105CZM Major Facilitator DJ46_114 ENOG4105DZ1 carboxypeptidase DJ46_1140 ENOG4105W8X HesB YadR YfhF-family protein DJ46_1142 ENOG4105DXD 2-methylcitrate dehydratase DJ46_1143 ENOG4105CR4 methylisocitrate lyase DJ46_1144 ENOG4105C1G acyl-Coa dehydrogenase DJ46_1145 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ46_1147 ENOG4105N14 lysine exporter protein LysE YggA DJ46_1148 ENOG4105E39 Enoyl-CoA hydratase DJ46_115 ENOG4105VFR signal peptidase DJ46_1151 ENOG4107RFY SbcCD D subunit DJ46_1152 ENOG4105EYH Exonuclease DJ46_1156 ENOG4105FCD Major Facilitator DJ46_1157 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DJ46_1158 ENOG4105E4F Isochorismate synthase DJ46_1159 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase DJ46_1160 ENOG4105WQI isochorismatase DJ46_1161 ENOG4105CEY Amp-dependent synthetase and ligase DJ46_1162 ENOG4105WQT MbtH domain protein DJ46_1163 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_1166 ENOG4105K70 DNA-binding protein DJ46_1170 ENOG4105BZG amino acid carrier protein DJ46_1174 ENOG4105FE9 pseudouridine synthase DJ46_1175 ENOG4105C22 threonyL-tRNA synthetase DJ46_1180 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DJ46_1186 ENOG4108D32 Methyltransferase DJ46_1192 ENOG41081I9 integral membrane protein DJ46_1195 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DJ46_1197 ENOG4105EYF MMPL domain protein DJ46_12 ENOG4107AYK membrAne DJ46_1202 ENOG4105WCN acetyltransferase DJ46_1208 ENOG4105C1Q protoporphyrinogen oxidase DJ46_121 ENOG4105C26 Dehydrogenase DJ46_1210 ENOG41068WN DJ46_1212 ENOG4105VEQ Cold shock protein DJ46_1216 ENOG410667J hydrolase DJ46_122 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ46_1224 ENOG4107V2S Transcriptional regulator DJ46_1225 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DJ46_1228 ENOG4105DND Transcriptional regulator DJ46_1229 ENOG4108RPX mosc domain containing protein DJ46_123 ENOG4105F38 ABC transporter, permease DJ46_1232 ENOG4105BZ1 (ABC) transporter DJ46_1233 ENOG4105BZ1 (ABC) transporter DJ46_1237 ENOG4108JCI Transcriptional regulator DJ46_124 ENOG4105D38 putrescine abc transporter DJ46_1242 ENOG4108KPJ rna polymerase sigma factor DJ46_1247 ENOG4105F32 YngK protein DJ46_125 ENOG4107RUE extracellular solute-binding protein family 1 DJ46_1252 ENOG4105RD7 BadF BadG BcrA BcrD DJ46_1254 ENOG4107STF Involved in phosphonate degradation (By similarity) DJ46_1257 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DJ46_1260 ENOG4105C1J atp-dependent rna helicase DJ46_1262 ENOG4108RZE Tetr family transcriptional regulator DJ46_1266 ENOG41088CC tellurite resistance protein tehB DJ46_1268 ENOG4108I0C methyltransferase DJ46_1269 ENOG4107RA9 decarboxylase DJ46_127 ENOG4105EYF MMPL domain protein DJ46_1270 ENOG41090HR transcriptional regulator DJ46_1278 ENOG4105CIN aminoacyl-histidine dipeptidase DJ46_1284 ENOG4107RF6 penicillin-binding protein DJ46_1285 ENOG4107RF6 penicillin-binding protein DJ46_1286 ENOG4107RF6 penicillin-binding protein DJ46_1288 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ46_1289 ENOG4105ETE Transcriptional regulator (LacI family DJ46_129 ENOG4108YBP pseudouridine synthase DJ46_1290 ENOG4105IE8 Alpha-ketoglutarate permease DJ46_1291 ENOG4105CK5 oxidoreductase DJ46_1296 ENOG4105D2N Aldolase DJ46_1297 ENOG4105DH8 myo-inositol catabolism DJ46_13 ENOG41073B9 DJ46_1301 ENOG4105CGH 5'-nucleotidase DJ46_1302 ENOG4105CGH 5'-nucleotidase DJ46_1305 ENOG4105VZ8 Transcriptional regulator DJ46_1308 ENOG4108VXD carboxy-peptidase DJ46_131 ENOG4105K4I Scp-like extracellular DJ46_1313 ENOG41067SE Tetr family transcriptional regulator DJ46_1314 ENOG4105C5H ABC transporter DJ46_1316 ENOG4105BZU Histidine kinase DJ46_1318 ENOG4106ANW SMI1_KNR4 DJ46_1319 ENOG4105CEP NADH dehydrogenase DJ46_132 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ46_1320 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) DJ46_1323 ENOG4105CJ1 ABC, transporter DJ46_1328 ENOG4105C1G acyl-Coa dehydrogenase DJ46_1329 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ46_133 ENOG4105CQB FAD linked oxidase domain protein DJ46_1330 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit DJ46_1331 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DJ46_1332 ENOG4105E39 Enoyl-CoA hydratase DJ46_1333 ENOG4107QX3 carboxylase DJ46_1334 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ46_1336 ENOG4105WCN acetyltransferase DJ46_1337 ENOG4105DBI uridine monophosphokinase DJ46_1340 ENOG4105DZ1 carboxypeptidase DJ46_1343 ENOG4105T9C HD domain DJ46_1345 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DJ46_1354 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DJ46_1354 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DJ46_1357 ENOG4105FQP Beta-lactamase DJ46_1359 ENOG4107Y80 Major Facilitator superfamily DJ46_136 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_1363 ENOG4105CUV Homoserine Kinase DJ46_1369 ENOG4105CPQ Dehydrogenase DJ46_137 ENOG4105BZU Histidine kinase DJ46_1372 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DJ46_1373 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DJ46_138 ENOG4105JXH GntR family transcriptional regulator DJ46_1394 ENOG4105ETU transcriptional activator (TenA DJ46_1417 ENOG410667J hydrolase DJ46_1419 ENOG4105BZU Histidine kinase DJ46_142 ENOG4106A3R peptidase DJ46_1420 ENOG4107RF6 penicillin-binding protein DJ46_1424 ENOG4108JJB ABC transporter DJ46_1427 ENOG4108HGU Histidine kinase DJ46_1430 ENOG4105CB2 alcohol dehydrogenase DJ46_1431 ENOG4105CJN penicillin-binding protein DJ46_1433 ENOG4105FQP Beta-lactamase DJ46_1439 ENOG4108V4B ThiJ pfpI DJ46_144 ENOG4108QTI )-transporter DJ46_1444 ENOG4107Y80 Major Facilitator superfamily DJ46_1448 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DJ46_145 ENOG4107TS3 membrane protein, TerC DJ46_1453 ENOG4107Y9U Membrane DJ46_1460 ENOG4105FCD Major Facilitator DJ46_1462 ENOG4105E09 nadh pyrophosphatase DJ46_1463 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DJ46_1464 ENOG4108Z4K mutator MutT protein DJ46_1471 ENOG4108XI2 Domain of unknown function (DUF1963) DJ46_1477 ENOG4108NRW Phospholipase, patatin family DJ46_1478 ENOG4105KWG Pfam:DUF1696 DJ46_148 ENOG410681C small acid-soluble spore protein DJ46_1486 ENOG4105PKS Excinuclease abc c subunit domain protein DJ46_149 ENOG4108Z7G MaoC domain protein dehydratase DJ46_1494 ENOG4107VFR oxidoreductase DJ46_1499 ENOG4105PAD Hydrolase DJ46_15 ENOG4108KP7 hydrolase DJ46_1504 ENOG4105DY8 decarboxylase DJ46_1507 ENOG4108IUM Glycogen debranching enzyme DJ46_1512 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DJ46_1514 ENOG4105FDR Membrane DJ46_1521 ENOG4108V3A UPF0421 protein DJ46_1525 ENOG4105MSI germination protein ypeb DJ46_1529 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) DJ46_153 ENOG4105CHR reductase DJ46_1530 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) DJ46_1531 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) DJ46_1532 ENOG4107Z3H Transcriptional regulator, TetR family DJ46_1538 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family DJ46_1542 ENOG4105E98 transcriptional regulator DeoR family DJ46_1546 ENOG41062ES Transcriptional regulator DJ46_155 ENOG4105MWK D-amino acid dehydrogenase, small subunit DJ46_1551 ENOG4107QKR Dehydrogenase DJ46_1553 ENOG4107RUY (E1 component), alpha subunit DJ46_1555 ENOG4105E1F short-chain dehydrogenase reductase DJ46_1556 ENOG4105RHY Pfam:UPF0157 DJ46_1562 ENOG4107SQ8 Glycine betaine DJ46_1563 ENOG4108IJ7 Glycine betaine DJ46_1568 ENOG4105E66 phosphoriboisomerase A DJ46_1569 ENOG41082BV acetyltransferase DJ46_1570 ENOG4108M1A Chitin-binding protein DJ46_1579 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DJ46_1585 ENOG4108Z7F N-acetyltransferase DJ46_1589 ENOG4105EEM helicase DJ46_159 ENOG4105C4Y ABC transporter DJ46_1593 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ46_1602 ENOG4108M1A Chitin-binding protein DJ46_1605 ENOG4105BZG amino acid carrier protein DJ46_1606 ENOG4105C26 Dehydrogenase DJ46_1607 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DJ46_1608 ENOG4105CTU Proline racemase DJ46_1609 ENOG4105CTU Proline racemase DJ46_161 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ46_1610 ENOG41080HI glycine oxidase DJ46_1617 ENOG4107T5V SNARE associated Golgi DJ46_1620 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DJ46_1621 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DJ46_1624 ENOG4105DTQ mandelate racemase muconate lactonizing DJ46_1632 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) DJ46_1633 ENOG4105BZU Histidine kinase DJ46_1634 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_164 ENOG4107RCV ABC transporter, permease DJ46_1641 ENOG4105DPN Oligoendopeptidase f DJ46_1644 ENOG4105EPR degv family DJ46_165 ENOG4108KAZ Involved in phosphonate degradation (By similarity) DJ46_1652 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DJ46_1653 ENOG4106K7D Major facilitator family transporter DJ46_1657 ENOG4107BMA Transglycosylase associated protein DJ46_1660 ENOG41089UC methyltransferase, type 11 DJ46_1667 ENOG4105CHM Aminotransferase DJ46_1673 ENOG4105DVE abc transporter atp-binding protein DJ46_168 ENOG4105E98 transcriptional regulator DeoR family DJ46_1682 ENOG4105C02 permease DJ46_1684 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DJ46_1685 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DJ46_1686 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein DJ46_1691 ENOG4105E09 nadh pyrophosphatase DJ46_1695 ENOG4108AQF aminoglycoside N(3)-acetyltransferase DJ46_17 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DJ46_1705 ENOG4107VC0 DNA alkylation repair enzyme DJ46_1707 ENOG4107VMI polysaccharide deacetylase DJ46_1709 ENOG4108ZCF integral membrane protein DJ46_1710 ENOG4105E0M Sulfatase DJ46_1711 ENOG4105C5H ABC transporter DJ46_1713 ENOG4105EYF MMPL domain protein DJ46_1714 ENOG4105EYF MMPL domain protein DJ46_1715 ENOG41082JN Transcriptional regulator DJ46_1719 ENOG4105CIH Imidazole acetol-phosphate transaminase DJ46_1720 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase DJ46_1721 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DJ46_1729 ENOG41069ER domain protein DJ46_173 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) DJ46_1731 ENOG4105EMN RNA polymerase sigma factor DJ46_1737 ENOG4105D4B ABC, transporter DJ46_1739 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane DJ46_174 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) DJ46_1741 ENOG4105DKT Transcriptional regulator DJ46_1742 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) DJ46_1745 ENOG41061GT Aldolase DJ46_1749 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) DJ46_1755 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DJ46_1756 ENOG4105II7 pyrroline-5-carboxylate reductase DJ46_1758 ENOG4107258 Transcriptional regulator DJ46_176 ENOG4105PXI polysaccharide deacetylase DJ46_1760 ENOG4105E0Y RtcB Protein DJ46_1761 ENOG4105ECK Fatty Acid Desaturase DJ46_1762 ENOG4105G6Z alkaline phosphatase DJ46_1764 ENOG4105VMP Transcriptional regulator DJ46_1767 ENOG41090T1 Membrane DJ46_1769 ENOG4108WCX response regulator DJ46_1771 ENOG41068WN DJ46_1776 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ46_178 ENOG4105BZU Histidine kinase DJ46_1781 ENOG4105CKK Glycosyl transferase, family 2 DJ46_1786 ENOG4105CKK Glycosyl transferase, family 2 DJ46_1788 ENOG4105C8Y Acetylornithine aminotransferase DJ46_179 ENOG41090MY MarR family Transcriptional regulator DJ46_1797 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ46_1799 ENOG4108TVJ Nitroreductase DJ46_1800 ENOG4105FS7 Transcriptional regulator DJ46_1807 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ46_1809 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DJ46_181 ENOG4106DF1 DJ46_1815 ENOG4108XET gCN5-related N-acetyltransferase DJ46_183 ENOG4105BZU Histidine kinase DJ46_1832 ENOG410635A Membrane DJ46_1833 ENOG4105KNA -acetyltransferase DJ46_1834 ENOG4108IQI permease DJ46_1836 ENOG4105F1N DNA alkylation repair DJ46_1844 ENOG4107RF6 penicillin-binding protein DJ46_1846 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DJ46_185 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DJ46_1853 ENOG4105P4J Allophanate hydrolase, subunit 1 DJ46_1854 ENOG4107258 Transcriptional regulator DJ46_1856 ENOG4106N3A copper homeostasis protein cutc DJ46_1857 ENOG4108ZRV stage ii sporulation protein p DJ46_1858 ENOG4108ZHR arsR family transcriptional regulator DJ46_186 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DJ46_1860 ENOG4105FDT acyl-CoA dehydrogenase DJ46_1864 ENOG4105DWD nucleoside recognition domain protein DJ46_1870 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) DJ46_1885 ENOG4105E2A Dehydrogenase DJ46_1888 ENOG4108IJ0 Aspartate ammonia-lyase DJ46_1889 ENOG4105HDK L-asparaginase DJ46_1890 ENOG4108IMY Transcriptional regulator DJ46_1892 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) DJ46_1893 ENOG4105CUB amino acid DJ46_1895 ENOG4105II7 pyrroline-5-carboxylate reductase DJ46_1897 ENOG4105C6K Malic enzyme DJ46_1899 ENOG4108NHD germination protein DJ46_1900 ENOG4108NHD germination protein DJ46_1901 ENOG4108Q8B Spore germination protein DJ46_1906 ENOG4105CSV Glutaminase DJ46_1914 ENOG4105CGH 5'-nucleotidase DJ46_1915 ENOG4105CH6 catalase DJ46_1917 ENOG4105CHJ isochorismatase hydrolase DJ46_1923 ENOG41090MY MarR family Transcriptional regulator DJ46_1931 ENOG4108606 TspO/MBR family DJ46_1932 ENOG4105CVP deoxyribo-dipyrimidine photolyase DJ46_1935 ENOG4108TWJ NADH dehydrogenase subunit 5 DJ46_1936 ENOG4105GPN Uncharacterized conserved protein (DUF2294) DJ46_1938 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DJ46_1939 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) DJ46_1940 ENOG4105DSE periplasmic solute binding protein DJ46_1941 ENOG4105CC5 ABC transporter DJ46_1942 ENOG4105DIK (ABC) transporter DJ46_1948 ENOG4105D6J arsenicaL-resistance protein DJ46_1949 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_195 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) DJ46_1950 ENOG41085FC arsR family transcriptional regulator DJ46_1954 ENOG4105F7F Chaperone DJ46_1956 ENOG4105CHR reductase DJ46_1957 ENOG4108YXU transcriptional regulator AsnC family DJ46_196 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ46_1971 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DJ46_1972 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_1974 ENOG4105IIP Membrane DJ46_1977 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_1978 ENOG41062D9 Histidine kinase DJ46_198 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ46_1983 ENOG4105K6H D-cysteine desulfhydrase DJ46_1989 ENOG4105VZ8 Transcriptional regulator DJ46_199 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ46_1992 ENOG4108NNI Beta-lactamase domain-containing protein DJ46_1993 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase DJ46_1995 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ46_1996 ENOG4105JQZ Methyltransferase DJ46_1999 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DJ46_2 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) DJ46_200 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DJ46_2000 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) DJ46_2003 ENOG4105BZU Histidine kinase DJ46_2006 ENOG4108U05 Transcriptional regulator DJ46_2007 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 DJ46_2009 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DJ46_201 ENOG4105CZV ABC transporter DJ46_2010 ENOG4105DJB Major Facilitator Superfamily DJ46_2011 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) DJ46_2012 ENOG4107QR9 Iron-sulfur cluster binding protein DJ46_2014 ENOG4106P55 Transcriptional regulator DJ46_2016 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ46_2022 ENOG4105TRI Hydrolase DJ46_203 ENOG4105CJ1 ABC, transporter DJ46_2030 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ46_2033 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_2038 ENOG4107QJQ Mate efflux family protein DJ46_2041 ENOG4105MZU cell filamentation protein DJ46_2042 ENOG4105EQ0 Major Facilitator superfamily DJ46_2043 ENOG4108JGH Tetr family transcriptional regulator DJ46_2046 ENOG4105C44 Serine transporter DJ46_2047 ENOG4105EJQ L-serine dehydratase DJ46_2049 ENOG4108JPW Aminotransferase DJ46_2052 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) DJ46_2054 ENOG4105DVH amino acid DJ46_2057 ENOG4108JQ1 Dehydrogenase DJ46_2061 ENOG4108AEY RNA polymerase sigma factor DJ46_2064 ENOG41082W1 Cupin 2, conserved barrel domain protein DJ46_2065 ENOG410874W AraC family transcriptional regulator DJ46_2068 ENOG4105HIR S-layer domain protein DJ46_2076 ENOG4108ISG Major Facilitator DJ46_2078 ENOG4107MII Sugar-specific transcriptional regulator TrmB DJ46_2079 ENOG4105CZM Major Facilitator DJ46_2083 ENOG4105DA5 (ABC) transporter DJ46_2084 ENOG41069JR DJ46_2086 ENOG4105RXJ DJ46_2087 ENOG4105KPY Small multidrug resistance protein DJ46_2088 ENOG4105KBX Transcriptional regulator, TetR family DJ46_2090 ENOG4105CRW Short chain fatty acid transporter DJ46_2092 ENOG4105DYS nad(p)h dehydrogenase (quinone) DJ46_2098 ENOG4108JJB ABC transporter DJ46_2099 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DJ46_2104 ENOG4108K8S endonuclease I DJ46_2107 ENOG41067QW Transcriptional regulator DJ46_2109 ENOG4108Z66 YbaK ebsC protein DJ46_211 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ46_2110 ENOG4105CUT histidyl-tRNA synthetase DJ46_2113 ENOG4105KVH Transcriptional regulator DJ46_2114 ENOG4108RCM Nitroreductase DJ46_2118 ENOG4108PSK reductase DJ46_212 ENOG4105EA8 2-Nitropropane dioxygenase DJ46_2120 ENOG4105CJ1 ABC, transporter DJ46_213 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DJ46_2132 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_2133 ENOG4105DKQ ROK family DJ46_2134 ENOG4106UW1 Major Facilitator superfamily DJ46_2135 ENOG4108UW5 maltose o-acetyltransferase DJ46_2137 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DJ46_2139 ENOG4105C31 Tryptophanyl-tRNA synthetase DJ46_2140 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DJ46_2145 ENOG4105DMQ Methyltransferase DJ46_2147 ENOG4105EV4 Multidrug resistance protein mdtH DJ46_215 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ46_2153 ENOG4105C37 (CBS) domain DJ46_2156 ENOG4105DDN Pentapeptide repeat-containing protein DJ46_2157 ENOG4105XDF Protein of unknown function (DUF1272) DJ46_2158 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) DJ46_2159 ENOG4105CMG Carbohydrate kinase DJ46_2160 ENOG4105C6Z Gluconate DJ46_2161 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DJ46_2164 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DJ46_2165 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DJ46_2166 ENOG4105CIS alcohol dehydrogenase DJ46_2167 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone DJ46_2170 ENOG4105EWI Short-chain dehydrogenase reductase Sdr DJ46_2171 ENOG4105D4Y metalloprotease DJ46_2175 ENOG4105CV8 reductase DJ46_2176 ENOG4105F27 Major Facilitator DJ46_2179 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) DJ46_2180 ENOG4105C44 Serine transporter DJ46_2186 ENOG4105KVH Transcriptional regulator DJ46_2187 ENOG4108TZY GntR Family Transcriptional Regulator DJ46_2188 ENOG4105D9R oxidoreductase DJ46_2190 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DJ46_2191 ENOG4105KVH Transcriptional regulator DJ46_2192 ENOG4105KVH Transcriptional regulator DJ46_2199 ENOG4105JAB phenazine biosynthesis protein, phzf family DJ46_22 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ46_220 ENOG4105NQC Flavodoxin DJ46_2201 ENOG4105CHR reductase DJ46_2205 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein DJ46_2206 ENOG4105KVH Transcriptional regulator DJ46_2210 ENOG4108ZJ4 polysaccharide deacetylase DJ46_2220 ENOG4105KAF membrAne DJ46_2225 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) DJ46_2229 ENOG4107YXZ hydrolase, family 25 DJ46_2234 ENOG4105ED2 Beta-lactamase DJ46_2236 ENOG4105H3G oxidoreductase DJ46_2243 ENOG4105CIS alcohol dehydrogenase DJ46_2250 ENOG4108TN2 lmbE family DJ46_2252 ENOG4107R3E Citrate transporter DJ46_2256 ENOG4108MES Periplasmic binding protein DJ46_2258 ENOG4105EHG Permease protein DJ46_2259 ENOG4105DQ5 transport system permease protein DJ46_2260 ENOG4105NX3 Membrane DJ46_2261 ENOG4107ZY0 Phenazine biosynthesis-like protein DJ46_2265 ENOG4107CUJ Protein of unknown function (DUF2690) DJ46_2267 ENOG4107V2S Transcriptional regulator DJ46_227 ENOG4107QMU Mate efflux family protein DJ46_2271 ENOG4105C98 muts2 protein DJ46_2273 ENOG4105E5K Alpha-amylase DJ46_2274 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase DJ46_2275 ENOG4105DPN Oligoendopeptidase f DJ46_2276 ENOG4108A04 Beta-lactamase DJ46_228 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DJ46_2282 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DJ46_2286 ENOG41082BM Transcriptional regulator, arsr family DJ46_2287 ENOG4105CIS alcohol dehydrogenase DJ46_2293 ENOG4105RHY Pfam:UPF0157 DJ46_2295 ENOG4105C09 Bile acid DJ46_2296 ENOG4105CQB FAD linked oxidase domain protein DJ46_23 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DJ46_2300 ENOG4108UT6 Transferase hexapeptide repeat containing protein DJ46_2302 ENOG4105K64 Glycosyl transferase, family 2 DJ46_2303 ENOG4105E39 Enoyl-CoA hydratase DJ46_2305 ENOG4105KT7 mgtC SapB transporter DJ46_2307 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_2308 ENOG41073R8 VanW family DJ46_2310 ENOG4108R1P DJ46_2314 ENOG4105VEQ Cold shock protein DJ46_2318 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DJ46_2322 ENOG410904N short-chain dehydrogenase reductase DJ46_2324 ENOG4106IQC argininosuccinate lyase DJ46_2327 ENOG4108IA2 Sodium pantothenate symporter DJ46_2329 ENOG4105C26 Dehydrogenase DJ46_2330 ENOG4105CHR reductase DJ46_2332 ENOG4105EWU Squalene--hopene cyclase DJ46_2334 ENOG4105FR1 rard protein DJ46_2335 ENOG410696E Membrane DJ46_2338 ENOG4105D1F ATP-binding protein DJ46_234 ENOG4105CZN Potassium uptake protein DJ46_2340 ENOG4108ZAF Molybdopterin DJ46_2341 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ46_2342 ENOG4105D06 uba thif-type nad fad binding protein DJ46_2343 ENOG4105TMB Formate nitrite transporter DJ46_2345 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DJ46_2346 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) DJ46_2348 ENOG4108JB9 formate dehydrogenase DJ46_235 ENOG41063Y9 DJ46_2350 ENOG4105E1K spore germination protein DJ46_236 ENOG4105KBJ sporulation protein ytfj DJ46_2362 ENOG4107QJT sodium dicarboxylate symporter DJ46_2363 ENOG4108KGH TRANSCRIPTIONal DJ46_2365 ENOG4105EMN RNA polymerase sigma factor DJ46_2369 ENOG4105CIG ABC transporter DJ46_2371 ENOG4105D9R oxidoreductase DJ46_2373 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ46_2374 ENOG4105K4P CoA-binding domain protein DJ46_2375 ENOG4105C0H protease DJ46_2376 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_2378 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase DJ46_2379 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DJ46_2380 ENOG4105W8X HesB YadR YfhF-family protein DJ46_2386 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DJ46_2387 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ46_2389 ENOG4108JJA ABC, transporter DJ46_2390 ENOG4108I0Z Aconitate hydratase DJ46_2396 ENOG4105E5W Transporter DJ46_2398 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DJ46_2402 ENOG4107F3J Amp-dependent synthetase and ligase DJ46_2403 ENOG4107ZYJ bioY protein DJ46_2404 ENOG4105CEY Amp-dependent synthetase and ligase DJ46_241 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ46_2413 ENOG4107AYK membrAne DJ46_2415 ENOG4105BZU Histidine kinase DJ46_2416 ENOG4105FBA Phospholipase Carboxylesterase DJ46_2417 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase DJ46_2418 ENOG4105CK7 Sodium proline symporter DJ46_2419 ENOG4105CBC glutamate synthase DJ46_242 ENOG4105C7K acetolactate synthase DJ46_2420 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DJ46_2421 ENOG4108VJ1 Transcriptional regulator (CarD family DJ46_2422 ENOG4108903 Formimidoylglutamase DJ46_2427 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) DJ46_243 ENOG4108ZP8 Acetolactate synthase small subunit DJ46_2438 ENOG4107QIV Cytochrome c biogenesis protein DJ46_244 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DJ46_2440 ENOG4107RSM transcriptional regulator DJ46_2441 ENOG4105VAW lrga family DJ46_2442 ENOG41067MG lrgb family DJ46_2447 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ46_2450 ENOG4105BZ1 (ABC) transporter DJ46_2451 ENOG4105BZ1 (ABC) transporter DJ46_2455 ENOG4105D7V transposase DJ46_2458 ENOG4105D5T phosphonate abc transporter DJ46_246 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DJ46_2461 ENOG4105CGH 5'-nucleotidase DJ46_2463 ENOG4108SVB resolvase DJ46_2467 ENOG4105K7K Transcriptional regulator DJ46_2475 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase DJ46_2476 ENOG4105XSJ toxin secretion phage lysis holin DJ46_251 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DJ46_2516 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) DJ46_2537 ENOG4105C5F glutamine synthetase DJ46_2538 ENOG4105KV4 Transcriptional regulator DJ46_2539 ENOG4105CXI aluminum resistance protein DJ46_2540 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ46_2541 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ46_2542 ENOG4105EN6 Membrane DJ46_2543 ENOG4106F1P AAA ATPase, central domain protein DJ46_2550 ENOG41069ER domain protein DJ46_2551 ENOG4105DM4 PTS System DJ46_2552 ENOG4105DE4 1-phosphofructokinase DJ46_2553 ENOG4105E98 transcriptional regulator DeoR family DJ46_2554 ENOG4107QW4 alcohol dehydrogenase DJ46_2555 ENOG4107QW4 alcohol dehydrogenase DJ46_2556 ENOG4108SJC Membrane DJ46_2559 ENOG4105C85 amino acid DJ46_2563 ENOG4105TMB Formate nitrite transporter DJ46_2564 ENOG4105K70 DNA-binding protein DJ46_2565 ENOG4105C59 p-type ATPase DJ46_2566 ENOG410681U heavy metal transport detoxification protein DJ46_2567 ENOG4105VPX protein, conserved in bacteria DJ46_2569 ENOG4105NIV Esterase DJ46_2570 ENOG4105E0A ABC, transporter DJ46_2575 ENOG4105CGK Exodeoxyribonuclease III DJ46_2577 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ46_2578 ENOG4105D03 DNA-3-methyladenine glycosylase II DJ46_258 ENOG4107RVV histidinol phosphate phosphatase, hisj family DJ46_2584 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_2585 ENOG4105BZU Histidine kinase DJ46_2588 ENOG41067MG lrgb family DJ46_2591 ENOG4107TTQ Alpha beta hydrolase fold DJ46_2592 ENOG4107YEI lmbE family DJ46_2596 ENOG4105F0V Cell wall hydrolase DJ46_2597 ENOG4107R6R udp-galactopyranose mutase DJ46_2598 ENOG4105E0M Sulfatase DJ46_2599 ENOG410890F Dynamin family DJ46_26 ENOG4105C31 Tryptophanyl-tRNA synthetase DJ46_2601 ENOG4107QHE Choloylglycine hydrolase DJ46_2606 ENOG4105DA5 (ABC) transporter DJ46_261 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DJ46_2611 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DJ46_2612 ENOG4105DQU oxidoreductase, subunit beta DJ46_2613 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein DJ46_2614 ENOG4108IGT Dipeptidase DJ46_2615 ENOG4105MCT stage V sporulation protein S DJ46_2616 ENOG4105D48 metallophosphoesterase DJ46_262 ENOG4105E0M Sulfatase DJ46_2621 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DJ46_2624 ENOG4105XZV Protein of unknown function (DUF3243) DJ46_2625 ENOG4108RKS Short-chain dehydrogenase reductase Sdr DJ46_2629 ENOG4105UIB (ABC) transporter DJ46_2630 ENOG4105UIB (ABC) transporter DJ46_2631 ENOG4108JQ9 ABC transporter DJ46_2632 ENOG4105DIH basic membrane DJ46_2633 ENOG4105FDP GntR family transcriptional regulator DJ46_2634 ENOG4107QZI cell division protein FtsK DJ46_2636 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit DJ46_2638 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DJ46_264 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DJ46_2640 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DJ46_2641 ENOG4108S0H Dipicolinic acid synthetase, b subunit DJ46_2642 ENOG4105E35 Dipicolinate synthase subunit A DJ46_2644 ENOG4105C1V Peptidase, M16 DJ46_2648 ENOG4105DTN riboflavin biosynthesis protein ribF DJ46_2649 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DJ46_2651 ENOG4105W7A Protein of unknown function (DUF503) DJ46_2653 ENOG4105VHM ribosomal protein DJ46_2654 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DJ46_2655 ENOG4105CHV Transcription elongation factor NusA DJ46_2657 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DJ46_2659 ENOG4105DZP Membrane-associated zinc metalloprotease DJ46_2660 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DJ46_2661 ENOG4105KNE Phosphatidate cytidylyltransferase DJ46_2662 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DJ46_2670 ENOG4108HE4 integrase family DJ46_2672 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ46_2674 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DJ46_2677 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) DJ46_268 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) DJ46_2682 ENOG4105VB6 UPF0109 protein DJ46_2686 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DJ46_2687 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DJ46_269 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DJ46_2690 ENOG4105CHR reductase DJ46_2691 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DJ46_2694 ENOG4105CB5 ATP-dependent DNA helicase recG DJ46_2695 ENOG4105DP4 dak2 domain fusion protein ylov DJ46_2696 ENOG4108ZAA Alkaline-shock protein DJ46_2698 ENOG4105FJ0 thiamine DJ46_2699 ENOG4105DJV ribulose-phosphate 3-epimerase DJ46_2700 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DJ46_2701 ENOG4105D9P serine threonine protein kinase DJ46_2702 ENOG4108ZF3 Phosphatase DJ46_2704 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DJ46_2706 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ46_2707 ENOG4105C25 Primosomal protein n' DJ46_2708 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DJ46_271 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ46_2712 ENOG4105DSJ YicC domain protein DJ46_2714 ENOG4105F23 Fibronectin-binding protein DJ46_2715 ENOG4105DC7 peptidase M24 DJ46_272 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DJ46_2726 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DJ46_273 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein DJ46_2731 ENOG4105C34 Pseudouridine synthase DJ46_2734 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DJ46_2736 ENOG4105DBK s4 domain protein DJ46_2737 ENOG41067XK integral membrane protein DJ46_2739 ENOG4105DFA alanine racemase domain protein DJ46_274 ENOG4105C8J )-transporter DJ46_2740 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DJ46_2741 ENOG4105WR5 sporulation protein, YlmC YmxH family DJ46_2743 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_2745 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DJ46_2746 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DJ46_2747 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) DJ46_2748 ENOG4105D4A Cell wall formation (By similarity) DJ46_2749 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DJ46_2750 ENOG4105CNI cell division protein FtsW DJ46_2753 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DJ46_2754 ENOG4105CJN penicillin-binding protein DJ46_2755 ENOG4105CJN penicillin-binding protein DJ46_2756 ENOG41068DC Essential cell division protein (By similarity) DJ46_2763 ENOG4105KNH Nucleic acid-binding protein DJ46_2773 ENOG4105XSJ toxin secretion phage lysis holin DJ46_278 ENOG4105DFD Na H antiporter DJ46_2790 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DJ46_2792 ENOG4105CAR Terminase, large subunit DJ46_2809 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DJ46_2812 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_282 ENOG4105ENE Histidine kinase DJ46_2823 ENOG4108IMY Transcriptional regulator DJ46_283 ENOG4105WH1 Two component transcriptional regulator luxr family DJ46_2831 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) DJ46_2833 ENOG41063PX domain protein DJ46_2834 ENOG4105D78 K07001 NTE family protein DJ46_2836 ENOG4105H20 Sporulation integral membrane protein YlbJ DJ46_2837 ENOG4106H78 methyltransferase DJ46_2842 ENOG4107TB6 phosphoglycerate mutase DJ46_2845 ENOG4106UY4 Inherit from COG: Scp-like extracellular DJ46_2855 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DJ46_2856 ENOG4105CNI cell division protein FtsW DJ46_2859 ENOG4108IAB Phoh family DJ46_2863 ENOG4105QA2 DJ46_2864 ENOG4105CI3 gtp-binding protein typa DJ46_2866 ENOG4105ECY inositol monophosphatase DJ46_287 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DJ46_2870 ENOG4105CXN decarboxylase DJ46_2879 ENOG4105C7S Dehydrogenase DJ46_2880 ENOG4105CPP Dehydrogenase, E1 component DJ46_2883 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ46_2884 ENOG4108X4Q Hydrolase DJ46_2886 ENOG4105CN5 Metallo-Beta-Lactamase DJ46_2887 ENOG4107ZYR domain protein DJ46_2894 ENOG4108XRC Protein of unknown function (DUF458) DJ46_2896 ENOG4107IN1 Protein of unknown function (DUF1797) DJ46_2899 ENOG4105EPM Diguanylate phosphodiesterase DJ46_29 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ46_2900 ENOG4105K6S Short-chain dehydrogenase reductase Sdr DJ46_2903 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) DJ46_2905 ENOG4105UIN DJ46_2916 ENOG4108HGU Histidine kinase DJ46_2918 ENOG4105CHM Aminotransferase DJ46_2919 ENOG4105FKQ transcriptional regulator DJ46_292 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DJ46_2920 ENOG4105EG2 ABC transporter, permease DJ46_2922 ENOG4107FKK extracellular solute-binding protein family 1 DJ46_2924 ENOG4105CG3 alpha amylase, catalytic region DJ46_2933 ENOG4105CHU acetyl-coa acetyltransferase DJ46_2940 ENOG4105K7K Transcriptional regulator DJ46_2941 ENOG4105DTD Dehydrogenase DJ46_2943 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DJ46_2945 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DJ46_2950 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) DJ46_2953 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ46_2954 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ46_2955 ENOG4106TD9 Diguanylate cyclase DJ46_2959 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DJ46_296 ENOG4105CJ3 phosphate transporter DJ46_2962 ENOG4105CID antiterminator DJ46_2964 ENOG4105FDP GntR family transcriptional regulator DJ46_2966 ENOG4105CE4 GlcNAc 6-P deacetylase DJ46_297 ENOG4107GRR phosphate transport regulator DJ46_2973 ENOG4107ZE5 PPIases accelerate the folding of proteins DJ46_2974 ENOG4105PTM secreted protein DJ46_2975 ENOG4105J7I hydrolase DJ46_2977 ENOG4105G6R Stage v sporulation protein ae DJ46_2979 ENOG4105CZ3 stage V sporulation protein ad DJ46_298 ENOG4105BZ4 penicillin-binding protein DJ46_2980 ENOG41090VF Stage v sporulation protein ac DJ46_2984 ENOG4105C8J )-transporter DJ46_2985 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_2987 ENOG41082AN stage II sporulation protein DJ46_2988 ENOG4105DZ1 carboxypeptidase DJ46_2989 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ46_2990 ENOG4105DVE abc transporter atp-binding protein DJ46_2996 ENOG4105D7N magnesium and cobalt transport protein CorA DJ46_3 ENOG4105CH6 catalase DJ46_30 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ46_300 ENOG4105BZU Histidine kinase DJ46_3001 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ46_3003 ENOG4105I3K Ferric uptake regulator, Fur family DJ46_3004 ENOG4105MZ9 stage II sporulation protein m DJ46_3008 ENOG4105CPC Aldo Keto reductase DJ46_301 ENOG4105I3N Conserved Protein DJ46_3010 ENOG4105RHY Pfam:UPF0157 DJ46_3014 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DJ46_3016 ENOG4105ETE Transcriptional regulator (LacI family DJ46_3017 ENOG4108YM7 Gcn5-related n-acetyltransferase DJ46_3021 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DJ46_3022 ENOG4108R6K riboflavin synthase, subunit alpha DJ46_3026 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) DJ46_3027 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DJ46_3028 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DJ46_3029 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DJ46_3031 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ46_3033 ENOG4105DFD Na H antiporter DJ46_3034 ENOG4105CGH 5'-nucleotidase DJ46_304 ENOG4105BZU Histidine kinase DJ46_3046 ENOG4108IXY short-chain dehydrogenase reductase DJ46_3047 ENOG41069FQ Metallo-beta-lactamase superfamily DJ46_3049 ENOG4105II7 pyrroline-5-carboxylate reductase DJ46_3050 ENOG4105EJQ L-serine dehydratase DJ46_3054 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ46_3056 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DJ46_3057 ENOG4105D9U N-acetyltransferase DJ46_3059 ENOG4108VZI ErfK ybiS ycfS ynhG family protein DJ46_3060 ENOG4108QEG Membrane DJ46_3061 ENOG4105CDA abc transporter atp-binding protein DJ46_3062 ENOG4105E5Q amino acid AbC transporter DJ46_3063 ENOG4108HW3 (ABC) transporter DJ46_3065 ENOG4105G7B Protein of unknown function (DUF2992) DJ46_3066 ENOG4105E09 nadh pyrophosphatase DJ46_3068 ENOG4105C7S Dehydrogenase DJ46_3069 ENOG4105CPP Dehydrogenase, E1 component DJ46_3073 ENOG4107RDP Dehydrogenase DJ46_3075 ENOG4108JUB Transcriptional regulator DJ46_3077 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ46_3080 ENOG4107QQR Sporulation DJ46_3081 ENOG4105S1Z Stage IV sporulation protein B DJ46_3082 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DJ46_3084 ENOG4105DX0 Hemolysin A DJ46_3086 ENOG4105CTB Polyprenyl synthetase DJ46_3091 ENOG4108ZSR alkaline shock protein DJ46_3092 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ46_3097 ENOG410644B Stage III sporulation protein af DJ46_3099 ENOG4105KQ4 Stage iii sporulation protein ad DJ46_3100 ENOG4108CQH stage III sporulation protein AC DJ46_3101 ENOG4105KR5 Stage iii sporulation protein DJ46_3102 ENOG4105CD2 stage iii sporulation protein aa DJ46_3107 ENOG4105DC7 peptidase M24 DJ46_311 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ46_3110 ENOG4105CBJ Metal-dependent enzyme DJ46_3111 ENOG4107YBY Hydrolase DJ46_3116 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) DJ46_3117 ENOG4105WZW rhodanese family DJ46_312 ENOG4105DZ1 carboxypeptidase DJ46_3121 ENOG41080TC multidrug resistance protein DJ46_3128 ENOG4105CJ1 ABC, transporter DJ46_3129 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ46_313 ENOG4108JIC nucleoside recognition domain protein DJ46_3135 ENOG4105C0D helicase DJ46_315 ENOG4105FE9 pseudouridine synthase DJ46_3159 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DJ46_3160 ENOG4105C3R Methionine synthase DJ46_3162 ENOG4105C28 cystathionine DJ46_3163 ENOG4105C28 cystathionine DJ46_3167 ENOG4105C5X domain protein DJ46_3169 ENOG4105DKQ ROK family DJ46_317 ENOG4107TWT Cytochrome c biogenesis protein DJ46_3171 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DJ46_3175 ENOG4108UTW Plays a role in the regulation of phosphate uptake DJ46_3176 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DJ46_3177 ENOG4105E2Z phosphate ABC transporter (Permease DJ46_3178 ENOG4105C8U phosphate abc transporter DJ46_3179 ENOG4105PWN phosphate abc transporter DJ46_318 ENOG4105CRE cytochrome C DJ46_3180 ENOG4107RF6 penicillin-binding protein DJ46_3182 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ46_3187 ENOG4105N80 Ferric uptake regulator, Fur family DJ46_3189 ENOG4105FDK ABC transporter DJ46_319 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_3190 ENOG4108JYZ YitT family DJ46_3191 ENOG41069ZM Protein of unknown function (DUF2624) DJ46_3196 ENOG4105EGD dinuclear metal center protein, YbgI family DJ46_3199 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_32 ENOG4108JQ7 (ABC) transporter DJ46_320 ENOG4105BZU Histidine kinase DJ46_3200 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DJ46_3205 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DJ46_3206 ENOG4105KG3 cytidine deaminase DJ46_3207 ENOG4107YR5 Diacylglycerol kinase DJ46_3209 ENOG4105CTJ Metal Dependent Phosphohydrolase DJ46_321 ENOG4108WBT adenosyltransferase DJ46_3210 ENOG4105C9A Phoh family DJ46_3212 ENOG41068P3 sporulation protein YqfC DJ46_3213 ENOG4105KTH gatB Yqey DJ46_3215 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DJ46_3216 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DJ46_3220 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ DJ46_3222 ENOG4105CSA Coproporphyrinogen iii oxidase DJ46_3223 ENOG4105KVH Transcriptional regulator DJ46_3228 ENOG4105TQK DNA polymerase iii, delta' subunit DJ46_3230 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DJ46_3231 ENOG4108UK2 deaminase DJ46_3232 ENOG4105KQC Competence protein DJ46_3234 ENOG4105DXX methyltransferase DJ46_3236 ENOG4108WF2 Metal Dependent Phosphohydrolase DJ46_3238 ENOG410812S Rna-binding protein DJ46_324 ENOG4108SAX Membrane DJ46_3240 ENOG4105CQW ribosome biogenesis GTPase YqeH DJ46_3241 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DJ46_3244 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_3249 ENOG4108TVJ Nitroreductase DJ46_3252 ENOG4105G6Z alkaline phosphatase DJ46_3254 ENOG4108MUZ hydrolase DJ46_326 ENOG4105T7X DJ46_3261 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin DJ46_3262 ENOG4105MIR Phenylalanine 4-monooxygenase DJ46_3264 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_3265 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_327 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ46_3273 ENOG4105S6R Iron-hydroxamate transporter permease subunit DJ46_3274 ENOG4108V5C ABC transporter DJ46_3276 ENOG4108EKI Dehydrogenase DJ46_3277 ENOG4105C28 cystathionine DJ46_328 ENOG4105I7S Abortive infection protein DJ46_3283 ENOG4107XRG penicillin-binding protein DJ46_3286 ENOG4105CFP Peptidase U32 DJ46_3287 ENOG4105XYU peptidase (U32 family) DJ46_3288 ENOG4108VQJ O-methyltransferase DJ46_3289 ENOG4105HHA aminodeoxychorismate lyase DJ46_3293 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DJ46_3295 ENOG4105C02 permease DJ46_3298 ENOG41060CR DJ46_3299 ENOG4105C7H Helicase, RecD TraA family DJ46_33 ENOG4105UQX Mate efflux family protein DJ46_330 ENOG4107RGJ metallophosphoesterase DJ46_3301 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) DJ46_3302 ENOG4105C3J Cysteine desulfurase DJ46_3304 ENOG4105D1H recombination factor protein RarA DJ46_3305 ENOG4108VCI transcription factor, rsfa family DJ46_3306 ENOG4105CUZ uba thif-type nad fad binding protein DJ46_3308 ENOG4105CUT histidyl-tRNA synthetase DJ46_331 ENOG4107X2D transcriptional regulator, merr family DJ46_3311 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DJ46_3313 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DJ46_3314 ENOG41076HS cation diffusion facilitator family transporter DJ46_3315 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DJ46_3317 ENOG4105CKP Polysaccharide Biosynthesis Protein DJ46_3318 ENOG4108QG2 Membrane DJ46_332 ENOG4108S6Z Negative regulator of genetic competence DJ46_3320 ENOG4105VIE preprotein translocase, subunit YajC DJ46_3323 ENOG41061AI Protein of unknown function (DUF2905) DJ46_3326 ENOG4108HUF Transporter DJ46_3328 ENOG4108IPJ Membrane DJ46_3329 ENOG4108IPJ Membrane DJ46_3330 ENOG41082BM Transcriptional regulator, arsr family DJ46_3335 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DJ46_3336 ENOG4108IYU L-aspartate oxidase DJ46_3339 ENOG4108RPX mosc domain containing protein DJ46_3340 ENOG4105CQC Prephenate dehydratase DJ46_3344 ENOG4105EWM Histidine kinase DJ46_3347 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control DJ46_3350 ENOG4105X36 (ribosomal) protein DJ46_3352 ENOG4105C03 ribonuclease DJ46_3355 ENOG4107QMS site-determining protein DJ46_3358 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DJ46_3359 ENOG4105DFF Rod shape-determining protein mreb DJ46_3363 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DJ46_3364 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DJ46_3366 ENOG41068KH stage VI sporulation protein D DJ46_3368 ENOG4105D52 delta-aminolevulinic acid dehydratase DJ46_337 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase DJ46_3373 ENOG4105K56 Transcriptional regulator DJ46_3377 ENOG4108IUQ atp-dependent protease DJ46_338 ENOG4107RB3 L-asparaginase DJ46_3383 ENOG4108QCI YvbH-like oligomerisation region DJ46_3387 ENOG4105M59 Phosphodiesterase, mj0936 family DJ46_3388 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) DJ46_3390 ENOG4108XJQ germination protein DJ46_3392 ENOG4108PCX Major Facilitator DJ46_3394 ENOG4105KBX Transcriptional regulator, TetR family DJ46_3397 ENOG4105PFC Transcriptional regulator DJ46_3400 ENOG4105DZC cytosine deaminase DJ46_3401 ENOG4105DZC cytosine deaminase DJ46_3402 ENOG4105DEF Extracellular solute-binding protein, family 5 DJ46_3403 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ46_3406 ENOG4108JQ7 (ABC) transporter DJ46_3407 ENOG4108HRK Histidine kinase DJ46_3408 ENOG4105DY9 regulatoR DJ46_3411 ENOG41067S9 phage shock protein C, PspC DJ46_3412 ENOG4108JCI Transcriptional regulator DJ46_3414 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) DJ46_3415 ENOG4108Z40 Transcriptional regulator DJ46_3416 ENOG4105RHA ABC transporter, permease DJ46_3417 ENOG4108IUX (ABC) transporter DJ46_3418 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family DJ46_3419 ENOG4105ER2 Ompa motb domain protein DJ46_3420 ENOG4105ER2 Ompa motb domain protein DJ46_3421 ENOG4105E14 MotA TolQ exbB proton channel DJ46_3422 ENOG4108VXD carboxy-peptidase DJ46_3424 ENOG4105E33 succinate dehydrogenase DJ46_3426 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit DJ46_3429 ENOG4105K63 Thioredoxin DJ46_3430 ENOG4105C10 Electron transfer flavoprotein DJ46_3431 ENOG4105BZJ Electron transfer flavoprotein DJ46_3432 ENOG41060WC Enoyl-CoA hydratase DJ46_3433 ENOG4107Z3H Transcriptional regulator, TetR family DJ46_3434 ENOG4105CEY Amp-dependent synthetase and ligase DJ46_3436 ENOG4105J76 Periplasmic binding protein DJ46_3437 ENOG4105S6R Iron-hydroxamate transporter permease subunit DJ46_3446 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_3449 ENOG4105DR4 Methyltransferase DJ46_345 ENOG4105S2F DJ46_3452 ENOG4105KFN sortase, SrtB family DJ46_3453 ENOG4105E0A ABC, transporter DJ46_3456 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) DJ46_3458 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) DJ46_346 ENOG41065D1 DJ46_3460 ENOG4105FE9 pseudouridine synthase DJ46_3463 ENOG4105DCG PHP domain protein DJ46_3470 ENOG4105C5S asparaginyl-tRNA synthetase DJ46_3471 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DJ46_3473 ENOG4108RWN rrna methyltransferase DJ46_3480 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_3481 ENOG4105CW7 secretion protein, HlyD family DJ46_3482 ENOG4108JGH Tetr family transcriptional regulator DJ46_3483 ENOG4105CN9 Peptidase m42 family protein DJ46_3487 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DJ46_3488 ENOG4105C22 threonyL-tRNA synthetase DJ46_3489 ENOG4108TDW sporulation protein YtxC DJ46_3493 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DJ46_3494 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DJ46_3495 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DJ46_3497 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DJ46_3498 ENOG4105C2M dna polymerase I DJ46_3499 ENOG4105BZU Histidine kinase DJ46_3500 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_3504 ENOG4108HMX isocitrate dehydrogenase (NADP) DJ46_3505 ENOG4105BZN citrate synthase DJ46_3507 ENOG4108REF Sporulation integral membrane protein ytvi DJ46_3508 ENOG4105FS0 cytoplasmic membrane protein DJ46_3513 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DJ46_3514 ENOG4105C6K Malic enzyme DJ46_3515 ENOG4105C0B DNA polymerase III (alpha subunit) DJ46_3516 ENOG4105VV2 DJ46_3518 ENOG4105SFS phosphoesterase RecJ domain protein DJ46_352 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) DJ46_3525 ENOG4105DC7 peptidase M24 DJ46_3532 ENOG4105Z7P Acetyltransferase (GNAT) family DJ46_3533 ENOG41082W1 Cupin 2, conserved barrel domain protein DJ46_3535 ENOG4105VZ8 Transcriptional regulator DJ46_3539 ENOG4107YZX Universal stress protein DJ46_3548 ENOG4108JYZ YitT family DJ46_355 ENOG4105XXQ heptaprenyl diphosphate synthase component I DJ46_3552 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DJ46_3554 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) DJ46_3555 ENOG4105KBJ sporulation protein ytfj DJ46_3558 ENOG4105EFZ amidohydrolase DJ46_3560 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ46_3565 ENOG4106KR7 LysR family Transcriptional regulator DJ46_3567 ENOG4105U5Y Transcriptional regulator DJ46_3568 ENOG4105U5Y Transcriptional regulator DJ46_357 ENOG4105EAH synthase DJ46_3570 ENOG4105C28 cystathionine DJ46_3574 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DJ46_3576 ENOG4105EMN RNA polymerase sigma factor DJ46_3579 ENOG4105F1V Acetoin utilization protein DJ46_3580 ENOG4105W87 Cbs domain DJ46_3581 ENOG4105DGU Histone deacetylase DJ46_3583 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_3585 ENOG4107SNB ankyrin repeat protein YahD DJ46_3586 ENOG4105EP9 oxidoreductase DJ46_3592 ENOG4105ETE Transcriptional regulator (LacI family DJ46_3596 ENOG4105C88 aminopeptidase DJ46_3605 ENOG4108VDD TRNA binding domain protein DJ46_361 ENOG4105CIH Imidazole acetol-phosphate transaminase DJ46_3611 ENOG4105C8F Beta-lactamase domain protein DJ46_3614 ENOG4108V15 phosphotransferase enzyme family DJ46_3615 ENOG4108IUM Glycogen debranching enzyme DJ46_3617 ENOG4107QSE Dipeptidase DJ46_3618 ENOG4107QSE Dipeptidase DJ46_3619 ENOG4105YW5 deoR family transcriptional regulator DJ46_362 ENOG41068YB TPR repeat-containing protein DJ46_3622 ENOG4105CBX hi0933 family DJ46_3629 ENOG4108VJ1 Transcriptional regulator (CarD family DJ46_3630 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DJ46_3631 ENOG4105CSC Glucose uptake protein DJ46_3634 ENOG4108ZAF Molybdopterin DJ46_3635 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein DJ46_3636 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ46_3638 ENOG4105D06 uba thif-type nad fad binding protein DJ46_3639 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DJ46_3643 ENOG41085GJ domain protein DJ46_3645 ENOG4105DWV Homoserine O-trans-acetylase DJ46_3647 ENOG4108B31 Spore germination protein DJ46_365 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) DJ46_3653 ENOG410605W Major Facilitator DJ46_3654 ENOG4107S91 Sodium hydrogen exchanger DJ46_3655 ENOG4105NCW Trka-c domain protein DJ46_3658 ENOG4105C19 ABC transporter DJ46_366 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DJ46_3662 ENOG4105N5T Radical SAM Protein DJ46_3664 ENOG4105DA5 (ABC) transporter DJ46_367 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit DJ46_3670 ENOG4105E8V Alpha Beta Hydrolase Fold protein DJ46_3671 ENOG4108Z0R Transferase DJ46_3672 ENOG4105YVM Phosphoesterase, PA-phosphatase related DJ46_3673 ENOG4105BZF Glycosyl transferase (Group 1 DJ46_3675 ENOG4108RIR Molybdenum cofactor biosynthesis protein DJ46_3685 ENOG4105EGD dinuclear metal center protein, YbgI family DJ46_3686 ENOG4105BZU Histidine kinase DJ46_3687 ENOG4105BZU Histidine kinase DJ46_3688 ENOG4107S9D Alpha beta hydrolase DJ46_3689 ENOG4107T7U Sulfatase DJ46_3693 ENOG4105D2X ABC transporter substrate-binding protein DJ46_3695 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component DJ46_3699 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DJ46_37 ENOG4108ZCF integral membrane protein DJ46_3706 ENOG4108V2W Carbonate dehydratase DJ46_3708 ENOG4105C4M (Ubiquinol oxidase) subunit I DJ46_3709 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DJ46_3718 ENOG41087YS Phage shock protein A DJ46_3725 ENOG4105BZU Histidine kinase DJ46_3726 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_373 ENOG4108JYZ YitT family DJ46_3731 ENOG4108UGV hypoxanthine phosphoribosyltransferase DJ46_3732 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) DJ46_3739 ENOG4107ZTW SNARE associated Golgi DJ46_374 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase DJ46_3742 ENOG4105C19 ABC transporter DJ46_3743 ENOG41086D8 Transcriptional regulator DJ46_3753 ENOG4105C6Z Gluconate DJ46_3754 ENOG4105FDP GntR family transcriptional regulator DJ46_3758 ENOG41069H0 dihydroorotase EC 3.5.2.3 DJ46_3764 ENOG4105DTQ mandelate racemase muconate lactonizing DJ46_3766 ENOG4108IPT Naphthoate synthase DJ46_3767 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) DJ46_3768 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) DJ46_3769 ENOG4105E4F Isochorismate synthase DJ46_377 ENOG4105FJR Lmbe family DJ46_3770 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DJ46_3772 ENOG4105VEQ Cold shock protein DJ46_3777 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) DJ46_3779 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) DJ46_378 ENOG4105CPK Glycosyl transferase (Group 1 DJ46_3781 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ46_3800 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ46_3809 ENOG4105KT7 mgtC SapB transporter DJ46_3811 ENOG4107PBV potassium channel DJ46_3812 ENOG4107QYV phosphohexose isomerase DJ46_3813 ENOG4105WG9 Conserved Protein DJ46_3815 ENOG4105CHM Aminotransferase DJ46_3816 ENOG4108ZB6 transcriptional regulator AsnC family DJ46_3817 ENOG4105C5I Dehydrogenase DJ46_3818 ENOG4108MUZ hydrolase DJ46_3820 ENOG4105C87 Aminotransferase class I and II DJ46_3823 ENOG4105Y38 Kinase-associated protein B DJ46_3825 ENOG4107R3E Citrate transporter DJ46_3828 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) DJ46_3829 ENOG4105KA0 thioesterase Superfamily protein DJ46_3833 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ46_3837 ENOG41069ER domain protein DJ46_3840 ENOG4105CEP NADH dehydrogenase DJ46_3846 ENOG4105EWC Purine nucleoside phosphorylase DJ46_3849 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DJ46_385 ENOG4105DVT helicase DJ46_3853 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ46_3854 ENOG4105C4B ABC transporter, permease DJ46_3855 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DJ46_386 ENOG4105YAC DJ46_3864 ENOG41083MR nifu domain-containing protein DJ46_3867 ENOG4108W5N phosphatidylglycerophosphatase a DJ46_3869 ENOG4105DYS nad(p)h dehydrogenase (quinone) DJ46_3870 ENOG4105D4U had-superfamily hydrolase, subfamily iia DJ46_3873 ENOG4105CBT Fructose-1,6-bisphosphatase DJ46_3876 ENOG4105MMD transcriptional regulator DJ46_3877 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DJ46_3878 ENOG4107TXC Transcriptional regulator DJ46_3879 ENOG41090T1 Membrane DJ46_3884 ENOG4105FAA peptidase M23 DJ46_3886 ENOG4105KZD Domain of unknown function (DUF1805) DJ46_3887 ENOG4107R8B 5'-nucleotidase DJ46_3890 ENOG4105DIW FeS assembly protein SUFB DJ46_3891 ENOG4108UNV SUF system FeS assembly protein, NifU family DJ46_3892 ENOG4105C9B Cysteine desulfurase DJ46_3893 ENOG4105JRK feS assembly protein SufD DJ46_3894 ENOG4105C3K feS assembly ATPase SufC DJ46_3895 ENOG4105D01 (LipO)protein DJ46_3896 ENOG4105D01 (LipO)protein DJ46_3897 ENOG4108UMI ABC transporter, permease DJ46_39 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ46_390 ENOG4105CSM endonuclease III DJ46_3903 ENOG41080E8 Transcriptional regulator, Spx MgsR family DJ46_3912 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ46_3918 ENOG4108W8B Beta-lactamase domain protein DJ46_3919 ENOG4105C1G acyl-Coa dehydrogenase DJ46_392 ENOG4105BZ4 penicillin-binding protein DJ46_3920 ENOG4105CHU acetyl-coa acetyltransferase DJ46_3923 ENOG4105DZ1 carboxypeptidase DJ46_3927 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer DJ46_3931 ENOG4108SUT Major Facilitator Superfamily DJ46_3932 ENOG4107R7I amino acid DJ46_3934 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DJ46_3936 ENOG4107AYK membrAne DJ46_3943 ENOG4107ZTW SNARE associated Golgi DJ46_3945 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein DJ46_3946 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_3947 ENOG4105BZU Histidine kinase DJ46_3949 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DJ46_3952 ENOG4105VG1 fes assembly suf system protein DJ46_3953 ENOG4105D4Y metalloprotease DJ46_3957 ENOG4107S91 Sodium hydrogen exchanger DJ46_3958 ENOG4105NCW Trka-c domain protein DJ46_3960 ENOG4108RMU ferritin dps family protein DJ46_3963 ENOG4108URH decarboxylase DJ46_3968 ENOG4105D9N nucleoside DJ46_3969 ENOG4105D9N nucleoside DJ46_3972 ENOG4108RYK Nad-dependent epimerase dehydratase DJ46_3977 ENOG4105CV8 reductase DJ46_3978 ENOG4105F27 Major Facilitator DJ46_3979 ENOG4105KVH Transcriptional regulator DJ46_3982 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DJ46_3983 ENOG4105D4A Cell wall formation (By similarity) DJ46_3985 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_3987 ENOG4105WMR Protein CrcB homolog DJ46_3988 ENOG4105WMR Protein CrcB homolog DJ46_3991 ENOG4108MK9 spermidine N(1)-acetyltransferase DJ46_3992 ENOG4108VY7 phosphate-starvation-inducible protein PsiE DJ46_3995 ENOG4108IPW abc transporter atp-binding protein DJ46_3996 ENOG4105CM4 permease protein DJ46_4 ENOG4105BZU Histidine kinase DJ46_4001 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DJ46_4003 ENOG4105XZU Preprotein translocase, subunit SecG DJ46_4004 ENOG41067MG lrgb family DJ46_4023 ENOG4105EFC phage portal protein HK97 family DJ46_4028 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ46_403 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DJ46_4030 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ46_4031 ENOG4105CP7 Triose-phosphate isomerase DJ46_4036 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_4040 ENOG41090VF Stage v sporulation protein ac DJ46_4041 ENOG4105CZ3 stage V sporulation protein ad DJ46_4044 ENOG4105H67 Protein of unknown function (DUF421) DJ46_4045 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DJ46_4046 ENOG4105KRI phosphocarrier protein (HPr DJ46_4048 ENOG4105CHW UPF0052 protein DJ46_405 ENOG4105DVT helicase DJ46_4050 ENOG4108Z4K mutator MutT protein DJ46_4052 ENOG4105C3M thioredoxin reductase DJ46_4054 ENOG4108S4C acetyltransferase DJ46_4058 ENOG41086DT Membrane protein of unknown function DJ46_406 ENOG4105CTD carboxy-peptidase DJ46_4060 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DJ46_4061 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DJ46_4062 ENOG4105D7V transposase DJ46_4065 ENOG4107TXC Transcriptional regulator DJ46_4069 ENOG4105HMI Membrane DJ46_4070 ENOG4105DUM transcriptional regulator, lysR family DJ46_4072 ENOG4108WS4 fmn reductase DJ46_4075 ENOG4105BZ1 (ABC) transporter DJ46_4077 ENOG4105CN1 protease DJ46_4078 ENOG4105CRP Part of the ABC transporter FtsEX involved in DJ46_4079 ENOG4105CAK Cell division ATP-binding protein ftsE DJ46_4081 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) DJ46_4082 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DJ46_4083 ENOG4105MS2 ribosomal subunit Interface protein DJ46_4084 ENOG4105VEQ Cold shock protein DJ46_4085 ENOG41081UC Inherit from COG: Competence protein DJ46_4088 ENOG4105KVH Transcriptional regulator DJ46_409 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DJ46_4090 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DJ46_4091 ENOG4108KGH TRANSCRIPTIONal DJ46_4092 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DJ46_4093 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ46_4094 ENOG4105ESV Glycosyl transferase, family 4 DJ46_4096 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DJ46_4099 ENOG410901P UPF0249 protein DJ46_41 ENOG4105DPN Oligoendopeptidase f DJ46_4100 ENOG4105F8D glycoside hydrolase family 4 DJ46_4101 ENOG4105VCP PTS System DJ46_4102 ENOG4105CK1 PTS System DJ46_4104 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) DJ46_4105 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DJ46_4106 ENOG4105VCP PTS System DJ46_4108 ENOG4105VZJ PTS System DJ46_411 ENOG4105C2W permease DJ46_4111 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_4112 ENOG4105ECB domain protein DJ46_4113 ENOG4107RSM transcriptional regulator DJ46_412 ENOG4105DHF Membrane DJ46_4122 ENOG4105DAA L-lactate DJ46_4124 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) DJ46_4126 ENOG4105E0M Sulfatase DJ46_4132 ENOG4107R8N Glycosyl transferase, family 2 DJ46_4134 ENOG4105C94 Transporter DJ46_4135 ENOG41069ER domain protein DJ46_414 ENOG410890F Dynamin family DJ46_4140 ENOG4105KBK Zinc finger, swim domain protein DJ46_4141 ENOG4105C0D helicase DJ46_4147 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_4149 ENOG4107RBB ABC transporter, permease DJ46_4150 ENOG4105C19 ABC transporter DJ46_4154 ENOG4105CXY transporter DJ46_4157 ENOG4105BZU Histidine kinase DJ46_4158 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_4159 ENOG4105CMR udp-glucose 4-epimerase DJ46_416 ENOG4108W0I acetyltransferase DJ46_4162 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DJ46_4163 ENOG4105EY8 ABC transporter DJ46_4173 ENOG4105MT0 Sporulation transcriptional regulator spoiiid DJ46_4175 ENOG4105FRN stage II sporulation protein DJ46_4178 ENOG4105DY9 regulatoR DJ46_4179 ENOG4108IUW ABC transporter DJ46_418 ENOG4105KHC sulfurtransferase DJ46_4183 ENOG4106778 Protein of unknown function (DUF1146) DJ46_4186 ENOG4105C8S subunit m DJ46_4187 ENOG4105D65 subunit l DJ46_4192 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DJ46_4193 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DJ46_4195 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DJ46_4196 ENOG4105BZU Histidine kinase DJ46_4206 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) DJ46_4207 ENOG41062M3 atp synthase DJ46_421 ENOG4106032 Glutathionylspermidine synthase DJ46_4212 ENOG4108YZG isomerase DJ46_4215 ENOG4108VGI doxx family DJ46_4216 ENOG4107XC4 flavin reductase domain protein, FMN-binding DJ46_4219 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ46_4221 ENOG4108ZXQ stage ii sporulation protein r DJ46_4222 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DJ46_4223 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) DJ46_4226 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DJ46_4227 ENOG4105CBT Fructose-1,6-bisphosphatase DJ46_4228 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DJ46_4235 ENOG4105C1G acyl-Coa dehydrogenase DJ46_4236 ENOG4105C1G acyl-Coa dehydrogenase DJ46_4237 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DJ46_4239 ENOG4105DF6 Fe-S oxidoreductase DJ46_4242 ENOG4105BZU Histidine kinase DJ46_4247 ENOG4105BZU Histidine kinase DJ46_4248 ENOG4105KCT ABC transporter DJ46_4249 ENOG4108M15 ABC transporter DJ46_4250 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) DJ46_4254 ENOG4105IIU Aminopeptidase DJ46_4258 ENOG4105EMN RNA polymerase sigma factor DJ46_4260 ENOG410684U Domain of unknown function (DUF1934) DJ46_4264 ENOG4105CYW agmatinase DJ46_4266 ENOG4105DXB Major Facilitator superfamily DJ46_4267 ENOG4107SWG transcriptional regulator MERR family DJ46_4268 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ46_4269 ENOG4105BZ4 penicillin-binding protein DJ46_4270 ENOG4108XFG YwhD family DJ46_4271 ENOG4108Z4T Peptidase M50 DJ46_4272 ENOG41069HH 4-oxalocrotonate tautomerase DJ46_4273 ENOG4105DCI Phosphohydrolase DJ46_4274 ENOG4108MES Periplasmic binding protein DJ46_4275 ENOG4105E0A ABC, transporter DJ46_4276 ENOG4105EHG Permease protein DJ46_4277 ENOG4105DQ5 transport system permease protein DJ46_4278 ENOG4105DQ5 transport system permease protein DJ46_4280 ENOG4108VCI transcription factor, rsfa family DJ46_4283 ENOG4108IJ2 phosphate acetyltransferase DJ46_4286 ENOG4108VKI Cell wall hydrolase DJ46_4290 ENOG4107SVH Potassium channel protein DJ46_4292 ENOG410667J hydrolase DJ46_4293 ENOG4105VCH membrane DJ46_4295 ENOG4108TU7 Inherit from COG: (ABC) transporter DJ46_4296 ENOG4105CJ1 ABC, transporter DJ46_4297 ENOG41090WU lipolytic protein G-D-S-L family DJ46_4300 ENOG4105D6E homoserine dehydrogenase DJ46_4305 ENOG4108Y4K DNA-binding transcriptional activator DJ46_4307 ENOG4105WH1 Two component transcriptional regulator luxr family DJ46_4308 ENOG4105BZU Histidine kinase DJ46_4309 ENOG4105BZU Histidine kinase DJ46_4310 ENOG4105DWF phosphomethylpyrimidine kinase DJ46_4311 ENOG4105BZU Histidine kinase DJ46_4312 ENOG4105VCD cytoplasmic protein DJ46_4313 ENOG4105D22 carbon starvation protein DJ46_4314 ENOG4105DY9 regulatoR DJ46_4315 ENOG41079KZ Major Facilitator Superfamily DJ46_4320 ENOG4105EN6 Membrane DJ46_4321 ENOG4106YBV Methyl-accepting chemotaxis DJ46_4323 ENOG4108S4H thioesterase Superfamily protein DJ46_4325 ENOG4105JEU Glycosyl transferase, family 2 DJ46_4326 ENOG4105C5H ABC transporter DJ46_4331 ENOG4105CKK Glycosyl transferase, family 2 DJ46_4332 ENOG41067SE Tetr family transcriptional regulator DJ46_4334 ENOG4105E0X reductase DJ46_4335 ENOG4106F5Q Membrane DJ46_4338 ENOG4105DY9 regulatoR DJ46_4339 ENOG4108HRK Histidine kinase DJ46_4340 ENOG4107RGD Major Facilitator superfamily DJ46_4343 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ46_4345 ENOG4105IW1 AmiS UreI transporter DJ46_4347 ENOG4105CMR udp-glucose 4-epimerase DJ46_4348 ENOG4108UT2 hemolysin iii DJ46_435 ENOG4105CPK Glycosyl transferase (Group 1 DJ46_4350 ENOG4105C1J atp-dependent rna helicase DJ46_4353 ENOG4105DPN Oligoendopeptidase f DJ46_4357 ENOG4105C0H protease DJ46_4358 ENOG4105Q2H domain protein DJ46_4361 ENOG4105BZU Histidine kinase DJ46_4362 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_4368 ENOG4105CDU Replicative dna helicase DJ46_4370 ENOG4105BZR domain protein DJ46_4371 ENOG4108XMW Membrane DJ46_4373 ENOG4108UUM single-stranded DNA-binding protein DJ46_4375 ENOG4105C3G gtp-binding protein DJ46_4376 ENOG4105VDK protein, conserved in bacteria DJ46_4377 ENOG4105D8X mechanosensitive ion channel DJ46_4378 ENOG4108ZDA Sporulation protein YyaC DJ46_4379 ENOG4105FA0 parb-like partition protein DJ46_438 ENOG4108SZE gCN5-related N-acetyltransferase DJ46_4380 ENOG4107QJE Chromosome Partitioning Protein DJ46_4384 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) DJ46_4386 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DJ46_4390 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DJ46_4391 ENOG410848D S4 domain protein YaaA DJ46_4394 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ46_44 ENOG4108Z18 K06886 hemoglobin DJ46_4400 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DJ46_4407 ENOG4105ZMH deoxynucleoside kinase DJ46_4409 ENOG4105GTG Isochorismatase DJ46_4410 ENOG4108Z6B deaminase DJ46_4411 ENOG4105C6E dna polymerase iii DJ46_4415 ENOG41067KS pro-sigma K processing DJ46_442 ENOG41081VK Ribonuclease DJ46_4421 ENOG4105CXN decarboxylase DJ46_4423 ENOG4105FA2 dna polymerase iii DJ46_4424 ENOG4105MA4 psp1 domain protein DJ46_4426 ENOG41060K3 Methyltransferase DJ46_4428 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DJ46_4429 ENOG4105KRN Transcriptional regulator, abrb family DJ46_4431 ENOG4105F8V Hydrolase, tatD family DJ46_4432 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) DJ46_4434 ENOG4105XFA sporulation peptidase YabG DJ46_4435 ENOG4105W42 Veg protein DJ46_4438 ENOG4105DFT pur operon repressor DJ46_4439 ENOG4105KME endoribonuclease L-psp DJ46_4442 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DJ46_4443 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) DJ46_4445 ENOG4108JA2 transcriptioN-repair coupling factor DJ46_4446 ENOG4108M14 stage v sporulation protein t DJ46_4448 ENOG4108IY2 MazG family DJ46_4449 ENOG41082I2 s4 domain protein DJ46_4450 ENOG4105VYY sporulation protein yabp DJ46_4453 ENOG41060GV RNA binding s1 domain protein DJ46_4457 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DJ46_4458 ENOG4108UGV hypoxanthine phosphoribosyltransferase DJ46_4459 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DJ46_4462 ENOG4105C6T cysteine synthase DJ46_4463 ENOG4105CRQ synthase (Component I) DJ46_4464 ENOG4105DDQ anthranilate synthase DJ46_4465 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 DJ46_4466 ENOG4105EEI dihydropteroate synthase DJ46_4467 ENOG4105KRF dihydroneopterin aldolase DJ46_4468 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DJ46_4470 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DJ46_4476 ENOG4108Z0C Uvrb UvrC protein DJ46_4479 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DJ46_4481 ENOG4105CTP PilT protein domain protein DJ46_4485 ENOG4105D7W serine acetyltransferase DJ46_4488 ENOG4105C2N RNA methyltransferase TrmH family group 3 DJ46_4489 ENOG4105M0M Tetracycline resistance protein DJ46_4490 ENOG4105QIV RNA polymerase DJ46_4492 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DJ46_4497 ENOG4107Y49 methyltransferase DJ46_4499 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DJ46_45 ENOG4105MIX Adenylate cyclase DJ46_4500 ENOG4105XPM ribosomal protein DJ46_4521 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DJ46_4526 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DJ46_4528 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DJ46_4530 ENOG41067V7 50S ribosomal protein L36 DJ46_4536 ENOG4108JJB ABC transporter DJ46_4537 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DJ46_4538 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DJ46_4543 ENOG4105D1F ATP-binding protein DJ46_4546 ENOG4108NMV polysaccharide deacetylase DJ46_455 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ46_4564 ENOG4105C8B TIGR00159 family DJ46_4565 ENOG4107U5W ybbr family DJ46_4567 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DJ46_4568 ENOG4108VQT Alpha beta hydrolase fold protein DJ46_457 ENOG4107RWR Sodium hydrogen exchanger DJ46_4570 ENOG4105CMG Carbohydrate kinase DJ46_4571 ENOG4105CMG Carbohydrate kinase DJ46_4573 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) DJ46_4574 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein DJ46_458 ENOG4105CN5 Metallo-Beta-Lactamase DJ46_4582 ENOG4108PSK reductase DJ46_4583 ENOG4108UMI ABC transporter, permease DJ46_4584 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ46_4585 ENOG4105D01 (LipO)protein DJ46_4586 ENOG4105EE1 crotonyl-CoA reductase DJ46_4588 ENOG4105IQ5 FAD linked oxidase domain protein DJ46_459 ENOG4108Z5V transcriptional regulator, merr family DJ46_4591 ENOG4105C2C drug resistance transporter, Bcr CflA DJ46_4594 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ46_4595 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ46_4596 ENOG4105C3U ABC transporter DJ46_4597 ENOG4108JQ7 (ABC) transporter DJ46_4603 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ46_4604 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ46_4606 ENOG4105II7 pyrroline-5-carboxylate reductase DJ46_4607 ENOG4107XDY Nicotinamide Mononucleotide Transporter DJ46_4609 ENOG4105E0C molybdate abc transporter DJ46_461 ENOG4105H67 Protein of unknown function (DUF421) DJ46_4610 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DJ46_4611 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DJ46_4612 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family DJ46_4615 ENOG4105EGI Transcriptional regulator DJ46_4619 ENOG4105F6E Acyl-transferase DJ46_462 ENOG41080C8 DUF218 domain DJ46_4623 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DJ46_4626 ENOG4108RE7 deoxyribonuclease DJ46_4627 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) DJ46_4631 ENOG4105C5H ABC transporter DJ46_4634 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein DJ46_4636 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ46_4637 ENOG4105C3U ABC transporter DJ46_4638 ENOG4108JQ7 (ABC) transporter DJ46_4639 ENOG410667J hydrolase DJ46_4646 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DJ46_4647 ENOG4105ERH Fumarylacetoacetate hydrolase DJ46_4649 ENOG4108SC4 )-transporter DJ46_4650 ENOG4105CPF Cell wall formation (By similarity) DJ46_4651 ENOG4105CPF Cell wall formation (By similarity) DJ46_4652 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DJ46_4654 ENOG4107ZXI Rhomboid family DJ46_4657 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein DJ46_4658 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DJ46_4660 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) DJ46_4682 ENOG4105K8N protein family UPF0079, ATPase DJ46_4683 ENOG41072GX Peptidase M22 Glycoprotease DJ46_4684 ENOG410801F ribosomal-protein-alanine acetyltransferase DJ46_4685 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ46_4686 ENOG4105C5H ABC transporter DJ46_4689 ENOG4108TYN CAAX amino terminal protease family protein DJ46_4693 ENOG4105C7N Xanthine uracil vitamin C permease DJ46_4695 ENOG4105BZU Histidine kinase DJ46_4703 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DJ46_4709 ENOG4108SHN Glycosyl transferase, family 2 DJ46_4715 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DJ46_4719 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_4724 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DJ46_4725 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DJ46_4726 ENOG4105C83 adenylosuccinate lyase DJ46_4728 ENOG4105VR9 phosphoribosylformylglycinamidine synthase DJ46_473 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DJ46_4734 ENOG4108V3E phosphoribosylglycinamide formyltransferase DJ46_4736 ENOG4105C12 Phosphoribosylglycinamide synthetase DJ46_4741 ENOG4105C4R Atp-dependent dna helicase DJ46_4747 ENOG4108W2Y isochorismatase DJ46_4748 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ46_4749 ENOG4108UMI ABC transporter, permease DJ46_475 ENOG4107R0U MotA TolQ exbB proton channel DJ46_4750 ENOG4105D01 (LipO)protein DJ46_4754 ENOG4105D0U Arsenite-activated ATPase (ArsA) DJ46_4755 ENOG410834F Transcriptional regulator DJ46_4756 ENOG4107I77 yiaA/B two helix domain DJ46_476 ENOG4105ER2 Ompa motb domain protein DJ46_4760 ENOG4105CBD Diacylglycerol kinase DJ46_4761 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DJ46_4762 ENOG4108JPW Aminotransferase DJ46_4764 ENOG4105C26 Dehydrogenase DJ46_4765 ENOG4105KPY Small multidrug resistance protein DJ46_4769 ENOG4105D9N nucleoside DJ46_477 ENOG4107YTP response regulator receiver protein DJ46_4770 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DJ46_4773 ENOG4108W15 Protein of unknown function (DUF1456) DJ46_4776 ENOG4105DTQ mandelate racemase muconate lactonizing DJ46_4777 ENOG4105DFD Na H antiporter DJ46_478 ENOG4105CBS Chea signal transduction histidine kinase DJ46_4782 ENOG4105D3R alkyl hydroperoxide reductase DJ46_4783 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) DJ46_4785 ENOG4107W7X Aldolase DJ46_4786 ENOG4105EHG Permease protein DJ46_4787 ENOG4105DQ5 transport system permease protein DJ46_4788 ENOG4108V5C ABC transporter DJ46_479 ENOG4105CBS Chea signal transduction histidine kinase DJ46_4792 ENOG4106UIA DJ46_4793 ENOG4106UIA DJ46_4797 ENOG4105BZU Histidine kinase DJ46_48 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DJ46_480 ENOG4105DD5 Flagellar motor switch protein DJ46_4801 ENOG410756H nucleotidyltransferase DJ46_4802 ENOG4105D2S major facilitator superfamily DJ46_4805 ENOG4105E5Q amino acid AbC transporter DJ46_4806 ENOG4105EAB amino acid AbC transporter DJ46_4808 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_4809 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_4811 ENOG4105CI1 PTS System DJ46_4817 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter DJ46_4820 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DJ46_4823 ENOG4105C5H ABC transporter DJ46_4828 ENOG41062JF Transcriptional regulator DJ46_483 ENOG4105BZU Histidine kinase DJ46_4832 ENOG4105DEU major facilitator superfamily DJ46_4835 ENOG4107R1M Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity) DJ46_4838 ENOG4108N0M stress protein DJ46_4839 ENOG4106FN3 tellurium resistance protein DJ46_4840 ENOG4106FN3 tellurium resistance protein DJ46_4841 ENOG4107TS3 membrane protein, TerC DJ46_4842 ENOG4108TTB tellurium resistance protein DJ46_4846 ENOG4105KJF protein tyrosine phosphatase DJ46_4848 ENOG4107U9T Pfam:Ribonuclease_BN DJ46_4849 ENOG4105C59 p-type ATPase DJ46_4850 ENOG4108IPJ Membrane DJ46_4852 ENOG4105C3F Signal peptidase i DJ46_4856 ENOG4107ZTW SNARE associated Golgi DJ46_4859 ENOG410606W general stress protein DJ46_4860 ENOG4105UPD Calcium Proton DJ46_4868 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DJ46_4869 ENOG4105VTR Integrase DJ46_489 ENOG4105DTJ flagellar hook-associated protein DJ46_49 ENOG4105EMS pseudouridine synthase DJ46_4927 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DJ46_4929 ENOG4108JUB Transcriptional regulator DJ46_4931 ENOG4108IQI permease DJ46_4937 ENOG4105CSV Glutaminase DJ46_4939 ENOG4108A04 Beta-lactamase DJ46_494 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) DJ46_4942 ENOG4105CKK Glycosyl transferase, family 2 DJ46_4944 ENOG4107QQG Dehydrogenase DJ46_4945 ENOG4105C3I Nad-dependent epimerase dehydratase DJ46_4948 ENOG4105F1A Pyruvate formate-lyase DJ46_495 ENOG4108ZC9 flagellar basal-body rod protein flgc DJ46_4953 ENOG4105CI2 imidazolone-5-propionate hydrolase DJ46_4954 ENOG4105ECP epimerase DJ46_496 ENOG41075Z6 flagellar hook-basal body complex protein fliE DJ46_4960 ENOG41067AE Membrane-bound metal-dependent hydrolase DJ46_4961 ENOG4105CEN a g-specific adenine glycosylase DJ46_4962 ENOG4106BXE DJ46_4966 ENOG4105BZ1 (ABC) transporter DJ46_4967 ENOG4107NBY Membrane DJ46_4968 ENOG4105CBC glutamate synthase DJ46_497 ENOG4107U2N Flagellar M-ring protein DJ46_4970 ENOG4108IUW ABC transporter DJ46_4974 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ46_4975 ENOG4105G5W regulator Fur family DJ46_499 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DJ46_5000 ENOG4108JQC penicillin-binding protein 1A DJ46_5001 ENOG4107ZQN disulfide bond DJ46_5003 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DJ46_5005 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DJ46_5006 ENOG4105BZU Histidine kinase DJ46_5008 ENOG4105CYN Serine protein kinase DJ46_5012 ENOG4105C94 Transporter DJ46_5015 ENOG4105DZ6 Band 7 protein DJ46_5017 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism DJ46_5018 ENOG4108MRH transcriptional regulatory protein DJ46_5019 ENOG4105D4T Citrate transporter DJ46_5023 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DJ46_5024 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ46_5025 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DJ46_5026 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component DJ46_5027 ENOG4105BZ7 extracellular solute-binding protein family 1 DJ46_5028 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) DJ46_5029 ENOG4108STX response regulator DJ46_5030 ENOG4105US7 Histidine kinase DJ46_5035 ENOG4108MRH transcriptional regulatory protein DJ46_5037 ENOG4105C6K Malic enzyme DJ46_5039 ENOG4108UZ3 Transporter DJ46_5040 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ46_5042 ENOG4105BZU Histidine kinase DJ46_5043 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ46_5045 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DJ46_5046 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DJ46_5047 ENOG4108JB9 formate dehydrogenase DJ46_5052 ENOG4105CUB amino acid DJ46_5054 ENOG4105C59 p-type ATPase DJ46_5055 ENOG4105DAP Nicotinate phosphoribosyltransferase DJ46_506 ENOG4105BZE flagellar hook protein, FlgE DJ46_5062 ENOG41073R8 VanW family DJ46_5063 ENOG4108KGH TRANSCRIPTIONal DJ46_5064 ENOG4105D9N nucleoside DJ46_5065 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase DJ46_5066 ENOG4105C37 (CBS) domain DJ46_5067 ENOG4108IJ0 Aspartate ammonia-lyase DJ46_5068 ENOG4105DAA L-lactate DJ46_5071 ENOG4105DUX Transporter DJ46_5072 ENOG4108MES Periplasmic binding protein DJ46_5073 ENOG4105DQ5 transport system permease protein DJ46_5074 ENOG4108IHU transport system permease protein DJ46_5075 ENOG4105E0A ABC, transporter DJ46_5076 ENOG4105DMQ Methyltransferase DJ46_5078 ENOG4105EXW epimerase dehydratase DJ46_5080 ENOG4107T89 von Willebrand factor, type A DJ46_5081 ENOG4105GMT ATPase associated with various cellular activities aaa_5 DJ46_5082 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ46_5085 ENOG4105BZU Histidine kinase DJ46_5086 ENOG4105D5Q Arginine ornithine antiporter DJ46_5087 ENOG4107414 GntR family transcriptional regulator DJ46_5088 ENOG4105C5Y PTS System DJ46_5089 ENOG4105CG3 alpha amylase, catalytic region DJ46_5093 ENOG4105E1K spore germination protein DJ46_5095 ENOG4105CRN Aminoglycoside phosphotransferase DJ46_5096 ENOG4105BZG amino acid carrier protein DJ46_5097 ENOG4105CDA abc transporter atp-binding protein DJ46_5098 ENOG4105CT1 (ABC) transporter DJ46_5099 ENOG4105EAD ABC transporter DJ46_510 ENOG4107R88 Chemotaxis protein (CheV) DJ46_5100 ENOG4105DRP amino acid AbC transporter DJ46_5101 ENOG4108IQI permease DJ46_5106 ENOG4105D29 Helix-turn-helix type 11 domain protein DJ46_5107 ENOG4105NAE bifunctional deaminase-reductase domain protein DJ46_5108 ENOG4105BZU Histidine kinase DJ46_5111 ENOG4105CHH sulfate transporter DJ46_5112 ENOG41068KF Universal stress protein DJ46_5114 ENOG4105DEF Extracellular solute-binding protein, family 5 DJ46_5116 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ46_5117 ENOG4108JQ7 (ABC) transporter DJ46_5119 ENOG4105CXY transporter DJ46_512 ENOG4105K64 Glycosyl transferase, family 2 DJ46_5120 ENOG41067TZ transcriptional regulator, MarR family DJ46_5121 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_5122 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_5123 ENOG4105ETE Transcriptional regulator (LacI family DJ46_5124 ENOG4108RVA ribokinase DJ46_5126 ENOG4105C2J ABC transporter DJ46_5127 ENOG4105CNN ABC, transporter DJ46_5128 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DJ46_5129 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DJ46_5141 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DJ46_5142 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer DJ46_5143 ENOG41069ER domain protein DJ46_5144 ENOG4105VZ8 Transcriptional regulator DJ46_5145 ENOG4107D63 DJ46_5147 ENOG4105DUX Transporter DJ46_5151 ENOG4105C85 amino acid DJ46_5152 ENOG4105C7N Xanthine uracil vitamin C permease DJ46_5160 ENOG4105BZ9 Cytochrome C oxidase, subunit I DJ46_5161 ENOG4105E2S oxidase) subunit II DJ46_5164 ENOG4106CAD Protein of unknown function (DUF3311) DJ46_5165 ENOG4105E1V na solute symporter DJ46_5168 ENOG4108NHD germination protein DJ46_5169 ENOG4105CE1 Ferrous iron transport protein b DJ46_5170 ENOG4105CE1 Ferrous iron transport protein b DJ46_5171 ENOG4105CE1 Ferrous iron transport protein b DJ46_5172 ENOG4105CVA phosphate DJ46_5173 ENOG4105C8U phosphate abc transporter DJ46_5174 ENOG4105E2Z phosphate ABC transporter (Permease DJ46_518 ENOG4107TVC Glycosyl transferase, family 2 DJ46_52 ENOG4105CNI cell division protein FtsW DJ46_5201 ENOG41080XQ Signal transduction protein with cbs domains DJ46_5205 ENOG4105ETU transcriptional activator (TenA DJ46_5207 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DJ46_5209 ENOG4108VEU Thiamine monophosphate synthase DJ46_5210 ENOG41080HI glycine oxidase DJ46_5213 ENOG4105D06 uba thif-type nad fad binding protein DJ46_5214 ENOG4105DWF phosphomethylpyrimidine kinase DJ46_5223 ENOG4108INS Transcriptional regulator DJ46_5226 ENOG4105C7N Xanthine uracil vitamin C permease DJ46_523 ENOG4105I03 Flagellin DJ46_5233 ENOG4105C5Y PTS System DJ46_524 ENOG4105E4C Lytic transglycosylase catalytic DJ46_5240 ENOG4108B31 Spore germination protein DJ46_5245 ENOG4107Y03 Nitroreductase DJ46_5246 ENOG4105ED1 spovr family DJ46_525 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DJ46_5251 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase DJ46_5252 ENOG4105XTG Pfam:DUF156 DJ46_5253 ENOG4105VFE sira family DJ46_5254 ENOG4107TPS domain protein DJ46_5255 ENOG4105VFE sira family DJ46_5257 ENOG41085GJ domain protein DJ46_5259 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DJ46_5260 ENOG41087NI Sulfite exporter TauE/SafE DJ46_5262 ENOG4108KGH TRANSCRIPTIONal DJ46_5267 ENOG4105EMD TRANSCRIPTIONal DJ46_5268 ENOG4105VCP PTS System DJ46_5269 ENOG4105VZJ PTS System DJ46_527 ENOG4105DD5 Flagellar motor switch protein DJ46_5273 ENOG41069ER domain protein DJ46_5274 ENOG4107RBB ABC transporter, permease DJ46_5275 ENOG4105C19 ABC transporter DJ46_5281 ENOG4105WEF catalase DJ46_5288 ENOG4107T5V SNARE associated Golgi DJ46_529 ENOG4105CN7 Flagellar biosynthetic protein FliP DJ46_5294 ENOG4105CUB amino acid DJ46_5295 ENOG4107RWR Sodium hydrogen exchanger DJ46_5297 ENOG4106KNT transcriptional regulator DJ46_530 ENOG4105VS8 Flagellar biosynthetic protein fliq DJ46_5304 ENOG4108PCN EamA-like transporter family DJ46_5305 ENOG4108YXU transcriptional regulator AsnC family DJ46_5307 ENOG4105KPY Small multidrug resistance protein DJ46_5308 ENOG4105KPY Small multidrug resistance protein DJ46_5313 ENOG4105NF4 modulator of drug activity DJ46_5314 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DJ46_5315 ENOG4105E5W Transporter DJ46_5317 ENOG4107RKG DJ-1/PfpI family DJ46_5318 ENOG4105CH6 catalase DJ46_532 ENOG4105D00 flagellar biosynthetic protein flhB DJ46_5320 ENOG4105D5Q Arginine ornithine antiporter DJ46_5321 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DJ46_5323 ENOG4105C26 Dehydrogenase DJ46_5324 ENOG4105BZ1 (ABC) transporter DJ46_5325 ENOG4105BZ1 (ABC) transporter DJ46_5326 ENOG4105BZ1 (ABC) transporter DJ46_5328 ENOG4105DRP amino acid AbC transporter DJ46_5329 ENOG4105CDA abc transporter atp-binding protein DJ46_533 ENOG4105D7B Flagellar biosynthesis protein flha DJ46_5332 ENOG410839P DJ46_5339 ENOG4107FQX Alpha-acetolactate decarboxylase DJ46_534 ENOG4105FZW flagellar biosynthesis regulator FlhF DJ46_5344 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ46_5346 ENOG4105D4P Coproporphyrinogen iii oxidase DJ46_5349 ENOG4105CHH sulfate transporter DJ46_535 ENOG4105KTQ flagellar basal-body rod protein DJ46_5357 ENOG4106AKK s-layer domain-containing protein DJ46_5359 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ46_536 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DJ46_5360 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ46_5363 ENOG4105CGU Enoyl-CoA hydratase DJ46_5366 ENOG4105DER m42 family DJ46_5370 ENOG4105CTU Proline racemase DJ46_5378 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ46_5381 ENOG4108JQ7 (ABC) transporter DJ46_5387 ENOG4105CSH Transporter DJ46_5389 ENOG4108MRH transcriptional regulatory protein DJ46_5398 ENOG4105CDU Replicative dna helicase DJ46_54 ENOG4105K64 Glycosyl transferase, family 2 DJ46_5406 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_541 ENOG4108RZE Tetr family transcriptional regulator DJ46_5416 ENOG4107P5I polyketide synthase DJ46_5417 ENOG4108IG5 Transcriptional regulator DJ46_5421 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DJ46_5425 ENOG4105CMT Dihydroxyacetone kinase DJ46_5427 ENOG4105CMT Dihydroxyacetone kinase DJ46_5428 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DJ46_5429 ENOG410847I Transcriptional regulator, BadM Rrf2 family DJ46_5435 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DJ46_5448 ENOG4105WN5 stage II sporulation protein DJ46_545 ENOG4105KAC Antibiotic biosynthesis monooxygenase DJ46_5450 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ46_5452 ENOG4108MJI response regulator DJ46_5453 ENOG4105BZU Histidine kinase DJ46_5454 ENOG4105BZU Histidine kinase DJ46_5459 ENOG4105K8R UPF0145 protein DJ46_5465 ENOG4107VRP DNA repair exonuclease DJ46_5466 ENOG4106D4I domain protein DJ46_5467 ENOG4105D7V transposase DJ46_5470 ENOG4108IND Tetr family transcriptional regulator DJ46_5471 ENOG4105EQ0 Major Facilitator superfamily DJ46_5476 ENOG4108MUZ hydrolase DJ46_5480 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DJ46_5483 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DJ46_5486 ENOG4105EMN RNA polymerase sigma factor DJ46_5491 ENOG4105C57 major facilitator superfamily DJ46_5492 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ46_5494 ENOG4105EEM helicase DJ46_5495 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ46_550 ENOG4105DUM transcriptional regulator, lysR family DJ46_5500 ENOG4105K59 histidine triad (HIT) protein DJ46_5507 ENOG410905X membrane-flanked domain protein DJ46_5509 ENOG4105CKV Membrane DJ46_551 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ46_5519 ENOG410905X membrane-flanked domain protein DJ46_552 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DJ46_5520 ENOG4105CKV Membrane DJ46_5521 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation DJ46_5522 ENOG4105BZ4 penicillin-binding protein DJ46_5523 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DJ46_5525 ENOG4105C1Q protoporphyrinogen oxidase DJ46_553 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component DJ46_5530 ENOG4105NA0 Transcriptional regulator DJ46_5533 ENOG4105ECB domain protein DJ46_5539 ENOG4106AXD DJ46_554 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DJ46_5540 ENOG4108RQ5 Beta-lactamase domain-containing protein DJ46_5541 ENOG4105DF9 Lipoate-protein, ligase DJ46_5543 ENOG4105CEY Amp-dependent synthetase and ligase DJ46_5549 ENOG4105CNA YD repeat protein DJ46_5554 ENOG4105ENX hydrolase DJ46_5556 ENOG4107RN3 metallophosphoesterase DJ46_5557 ENOG4107TVP HD domain protein DJ46_5559 ENOG4108AEY RNA polymerase sigma factor DJ46_5560 ENOG41086D8 Transcriptional regulator DJ46_5564 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_5569 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 DJ46_5570 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_5574 ENOG4105ZU5 s-layer protein DJ46_5575 ENOG4107QP3 malate synthase g DJ46_5578 ENOG4105VEQ Cold shock protein DJ46_5581 ENOG4105XVF Competence transcription factor DJ46_5584 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination DJ46_5585 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation DJ46_5593 ENOG4105ERH Fumarylacetoacetate hydrolase DJ46_5607 ENOG4105EKQ RNA-directed DNA polymerase DJ46_561 ENOG4105CVJ phosphoglycerate mutase DJ46_5628 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DJ46_5635 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) DJ46_5637 ENOG4108MEK Metal-binding protein YodA DJ46_5639 ENOG4105DQ6 Transposase DJ46_5641 ENOG4105DQ6 Transposase DJ46_5644 ENOG4105DQ6 Transposase DJ46_5646 ENOG4108IBT Inherit from COG: transposase DJ46_5653 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ46_5655 ENOG4105KRN Transcriptional regulator, abrb family DJ46_5677 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DJ46_568 ENOG4105CAQ asparagine synthetase DJ46_5683 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) DJ46_5692 ENOG4105DQ6 Transposase DJ46_5693 ENOG4105DQ6 Transposase DJ46_5697 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ46_5698 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ46_5699 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ46_5703 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ46_5704 ENOG4106AKK s-layer domain-containing protein DJ46_5710 ENOG4105DHF Membrane DJ46_572 ENOG4105PGM cation diffusion facilitator family transporter DJ46_574 ENOG4105DRR Transcriptional regulator, GntR family DJ46_575 ENOG4108UZ3 Transporter DJ46_576 ENOG4105CKI cobalamin synthesis protein DJ46_5761 ENOG4105CNU cell division protein FtsK DJ46_577 ENOG4108PJD permease DJ46_5777 ENOG4106JUT Streptomycin 3''-adenylyltransferase DJ46_58 ENOG4107TVC Glycosyl transferase, family 2 DJ46_580 ENOG4105DFD Na H antiporter DJ46_581 ENOG4105C9Q fumarate hydratase class II DJ46_5810 ENOG4105K4H Nlp p60 protein DJ46_5825 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ46_5826 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ46_5836 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ46_5839 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ46_5845 ENOG4105N14 lysine exporter protein LysE YggA DJ46_585 ENOG4107QJQ Mate efflux family protein DJ46_5853 ENOG4105C3F Signal peptidase i DJ46_586 ENOG4107QJQ Mate efflux family protein DJ46_587 ENOG4105EC3 peptidase S51, dipeptidase E DJ46_5872 ENOG4105EWC Purine nucleoside phosphorylase DJ46_5879 ENOG4105DQ6 Transposase DJ46_5885 ENOG4107QJE Chromosome Partitioning Protein DJ46_591 ENOG4107QIV Cytochrome c biogenesis protein DJ46_598 ENOG4106BRA Membrane DJ46_605 ENOG4105CJ1 ABC, transporter DJ46_609 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) DJ46_611 ENOG4108IJ0 Aspartate ammonia-lyase DJ46_612 ENOG4105C6K Malic enzyme DJ46_62 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DJ46_625 ENOG4105FVX DJ46_63 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DJ46_633 ENOG4105CSR polyphosphate kinase 2 DJ46_634 ENOG4105DXI Major Facilitator superfamily DJ46_635 ENOG4105DXI Major Facilitator superfamily DJ46_638 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ46_641 ENOG4105EU0 Major facilitator Superfamily DJ46_642 ENOG4105C6T cysteine synthase DJ46_646 ENOG4105C8J )-transporter DJ46_648 ENOG4105X5K response regulator receiver protein DJ46_649 ENOG4105H67 Protein of unknown function (DUF421) DJ46_65 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DJ46_652 ENOG4106KE4 Dehydrogenase DJ46_656 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DJ46_657 ENOG4105CHR reductase DJ46_658 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ46_659 ENOG4105C7K acetolactate synthase DJ46_660 ENOG4108ZP8 Acetolactate synthase small subunit DJ46_661 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DJ46_663 ENOG4105C7B Threonine dehydratase DJ46_668 ENOG4105C6X Major Facilitator DJ46_669 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DJ46_671 ENOG4105DY9 regulatoR DJ46_672 ENOG4105CYC Transferase DJ46_677 ENOG4105F6J Alpha beta hydrolase fold DJ46_678 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ46_684 ENOG41068WN DJ46_689 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) DJ46_690 ENOG4105C72 UPF0176 protein DJ46_692 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DJ46_694 ENOG4105C0X amino acid DJ46_695 ENOG4105C0X amino acid DJ46_700 ENOG4107RHR regulatoR DJ46_702 ENOG4105D9N nucleoside DJ46_703 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DJ46_709 ENOG4107RAQ aminopeptidase DJ46_710 ENOG4107STQ Multicopper oxidase DJ46_711 ENOG4107R16 Multicopper oxidase DJ46_721 ENOG4108T5E Copper resistance protein DJ46_722 ENOG4105KTB nuclear export factor GLE1 DJ46_724 ENOG4107RT3 EamA-like transporter family DJ46_725 ENOG4105GZI Transcriptional regulator DJ46_726 ENOG4108Z40 Transcriptional regulator DJ46_727 ENOG4107ZXU DSBA oxidoreductase DJ46_728 ENOG4108TVJ Nitroreductase DJ46_730 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DJ46_731 ENOG4106F5Q Membrane DJ46_732 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ46_734 ENOG4105CKI cobalamin synthesis protein DJ46_738 ENOG4108Z7G MaoC domain protein dehydratase DJ46_739 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ46_74 ENOG4108WVJ 2'-5' rna ligase DJ46_741 ENOG4105C0Z ABC transporter DJ46_742 ENOG4108IV0 ABC, transporter DJ46_743 ENOG4105C32 Amino acid ABC transporter (Permease) DJ46_745 ENOG4105SKE transcriptional Regulator LysR family DJ46_747 ENOG4105MDS 4-oxalocrotonate tautomerase DJ46_749 ENOG4105YGB Transcriptional regulator DJ46_751 ENOG4105C4M (Ubiquinol oxidase) subunit I DJ46_752 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DJ46_753 ENOG4108JJ9 ABC, transporter DJ46_754 ENOG4108JJ8 (ABC) transporter DJ46_762 ENOG4105BZ1 (ABC) transporter DJ46_763 ENOG4105BZ1 (ABC) transporter DJ46_764 ENOG4105EFI regulatoR DJ46_765 ENOG4105BZU Histidine kinase DJ46_768 ENOG41075D4 Aminoglycoside 6-adenylyltransferase DJ46_769 ENOG4108ZJ4 polysaccharide deacetylase DJ46_773 ENOG4105D6E homoserine dehydrogenase DJ46_778 ENOG4108KGH TRANSCRIPTIONal DJ46_780 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ46_781 ENOG4105BZU Histidine kinase DJ46_782 ENOG4107VMI polysaccharide deacetylase DJ46_784 ENOG4105KT7 mgtC SapB transporter DJ46_785 ENOG4105VRR gCN5-related N-acetyltransferase DJ46_787 ENOG4105DUU IucA IucC family protein DJ46_788 ENOG4105CEY Amp-dependent synthetase and ligase DJ46_79 ENOG4105CK7 Sodium proline symporter DJ46_791 ENOG4108WBH protein TIM barrel DJ46_792 ENOG4105YWU small acid-soluble spore protein DJ46_794 ENOG4107RCC Major Facilitator Superfamily DJ46_796 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DJ46_8 ENOG4105QNR S1 RNA binding domain protein DJ46_80 ENOG4105CRQ synthase (Component I) DJ46_807 ENOG4105KRN Transcriptional regulator, abrb family DJ46_809 ENOG4105YVS arsR family transcriptional regulator DJ46_81 ENOG4105DDQ anthranilate synthase DJ46_810 ENOG4107SET aldo keto reductase DJ46_811 ENOG4107XZQ multidrug resistance protein DJ46_816 ENOG4105C8Q Methyl-accepting chemotaxis DJ46_819 ENOG4108K88 Membrane DJ46_820 ENOG4108WPJ Ferritin-like domain DJ46_823 ENOG4105DEN Luciferase family DJ46_827 ENOG4107QM2 Aldo Keto reductase DJ46_828 ENOG4105CKI cobalamin synthesis protein DJ46_839 ENOG4105DSE periplasmic solute binding protein DJ46_841 ENOG4105K4T epimerase DJ46_843 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ46_848 ENOG4105CVJ phosphoglycerate mutase DJ46_852 ENOG4107T5V SNARE associated Golgi DJ46_855 ENOG4108PJD permease DJ46_857 ENOG4108S4H thioesterase Superfamily protein DJ46_858 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ46_862 ENOG4105SXS Protein of unknown function (DUF456) DJ46_863 ENOG4105C37 (CBS) domain DJ46_867 ENOG4108Z7R Chaperone CsaA DJ46_871 ENOG4108ZRV stage ii sporulation protein p DJ46_873 ENOG4108VXD carboxy-peptidase DJ46_875 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DJ46_880 ENOG4108X4Q Hydrolase DJ46_882 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DJ46_883 ENOG4107RBS Methyltransferase DJ46_886 ENOG41087PP glycosyltransferase MGT family DJ46_887 ENOG4108JYZ YitT family DJ46_888 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ46_894 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DJ46_903 ENOG4105KBJ sporulation protein ytfj DJ46_908 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ46_912 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) DJ46_913 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ46_915 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DJ46_916 ENOG4105EMN RNA polymerase sigma factor DJ46_921 ENOG4108V06 Glutathione peroxidase DJ46_924 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ46_928 ENOG4108IUE nitrate reductase beta subunit DJ46_929 ENOG4105R3A Nitrate reductase DJ46_934 ENOG4107V6Q Cyclic nucleotide-binding domain DJ46_935 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DJ46_936 ENOG4105D06 uba thif-type nad fad binding protein DJ46_937 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ46_938 ENOG4108ZAF Molybdopterin DJ46_943 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein DJ46_944 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DJ46_945 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ46_946 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DJ46_947 ENOG4108IFG nitrite reductase, (NAD(P)H) DJ46_948 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) DJ46_955 ENOG4105MCT stage V sporulation protein S DJ46_958 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ46_962 ENOG4105C5H ABC transporter DJ46_965 ENOG4108UUM single-stranded DNA-binding protein DJ46_968 ENOG41061H0 Monooxygenase DJ46_972 ENOG4107YX5 Pfam:DUF548 DJ46_973 ENOG4105C75 arginyL-tRNA synthetase DJ46_979 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DJ46_982 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DJ46_983 ENOG4105C5S asparaginyl-tRNA synthetase DJ46_987 ENOG4105EC2 ftsk spoIIIe DJ46_99 ENOG4105C7S Dehydrogenase