locus-tag	class	description
KCX77_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCX77_00010	COG0592	DNA-directed DNA polymerase activity
KCX77_00015	COG2501	S4 domain
KCX77_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCX77_00030	COG0187	DNA topoisomerase II activity
KCX77_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCX77_00070	COG0516	GMP reductase activity
KCX77_00070	COG0517	IMP dehydrogenase activity
KCX77_00075	COG1686	Belongs to the peptidase S11 family
KCX77_00100	COG1428	Deoxynucleoside kinase
KCX77_00105	COG1428	Deoxynucleoside kinase
KCX77_00110	COG1388	LysM domain
KCX77_00110	COG3858	chitin binding
KCX77_00115	COG1335	isochorismatase
KCX77_00120	COG0590	tRNA wobble adenosine to inosine editing
KCX77_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCX77_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCX77_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCX77_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KCX77_00190	COG3853	Toxic anion resistance protein (TelA)
KCX77_00195	COG1982	Orn Lys Arg decarboxylase major
KCX77_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCX77_00205	COG3870	Protein conserved in bacteria
KCX77_00210	COG1728	Protein conserved in bacteria
KCX77_00215	COG0470	DNA polymerase III
KCX77_00220	COG1774	PSP1 C-terminal conserved region
KCX77_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KCX77_00235	COG2827	Endonuclease containing a URI domain
KCX77_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCX77_00245	COG2002	toxin-antitoxin pair type II binding
KCX77_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCX77_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCX77_00255	COG0084	hydrolase, TatD family'
KCX77_00260	COG3583	domain protein
KCX77_00260	COG3584	3D domain protein
KCX77_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCX77_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCX77_00280	COG4466	Protein conserved in bacteria
KCX77_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCX77_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCX77_00300	COG0251	oxidation-reduction process
KCX77_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCX77_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KCX77_00325	COG0193	aminoacyl-tRNA hydrolase activity
KCX77_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCX77_00340	COG2002	toxin-antitoxin pair type II binding
KCX77_00345	COG2244	polysaccharide biosynthetic process
KCX77_00350	COG3956	TIGRFAM MazG family protein
KCX77_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCX77_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KCX77_00375	COG1098	S1 RNA binding domain
KCX77_00390	COG2208	phosphoserine phosphatase activity
KCX77_00395	COG2304	oxidoreductase activity
KCX77_00400	COG0515	serine threonine protein kinase
KCX77_00405	COG0037	tRNA processing
KCX77_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCX77_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCX77_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCX77_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCX77_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCX77_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KCX77_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCX77_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCX77_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCX77_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCX77_00470	COG1396	sequence-specific DNA binding
KCX77_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCX77_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KCX77_00560	COG4463	regulation of RNA biosynthetic process
KCX77_00565	COG3880	PFAM UvrB UvrC protein
KCX77_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KCX77_00575	COG0542	response to heat
KCX77_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCX77_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KCX77_00590	COG4956	integral membrane protein (PIN domain superfamily)
KCX77_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCX77_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCX77_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCX77_00610	COG1045	serine acetyltransferase
KCX77_00615	COG0215	cysteine-tRNA ligase activity
KCX77_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCX77_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCX77_00630	COG3688	RNA-binding protein containing a PIN domain
KCX77_00635	COG1595	DNA-templated transcription, initiation
KCX77_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCX77_00650	COG0250	Participates in transcription elongation, termination and antitermination
KCX77_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCX77_00675	COG2813	Specifically methylates the guanine in position
KCX77_00680	COG0085	RNA polymerase activity
KCX77_00690	COG1358	cellular component organization or biogenesis
KCX77_00700	COG0049	tRNA binding
KCX77_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCX77_00715	COG0596	Alpha beta hydrolase
KCX77_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCX77_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCX77_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCX77_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCX77_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCX77_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCX77_00820	COG0200	Binds to the 23S rRNA
KCX77_00825	COG0201	protein transport
KCX77_00835	COG0024	Methionine aminopeptidase
KCX77_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KCX77_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCX77_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCX77_00870	COG0203	ribosomal protein L17
KCX77_00875	COG1122	ATPase activity
KCX77_00880	COG1122	ATPase activity
KCX77_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCX77_00890	COG0101	tRNA pseudouridine synthase activity
KCX77_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KCX77_00905	COG2226	methyltransferase
KCX77_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_00925	COG0489	protein tyrosine kinase activity
KCX77_00935	COG2194	sulfuric ester hydrolase activity
KCX77_00940	COG0726	polysaccharide deacetylase
KCX77_00970	COG0738	Major facilitator superfamily
KCX77_00975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCX77_00985	COG1063	alcohol dehydrogenase
KCX77_00990	COG0659	secondary active sulfate transmembrane transporter activity
KCX77_00995	COG0385	Bile acid
KCX77_01000	COG2819	hydrolase of the alpha beta superfamily
KCX77_01005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_01010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_01015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_01020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_01020	COG2207	Transcriptional regulator
KCX77_01025	COG3876	Protein conserved in bacteria
KCX77_01030	COG1472	Belongs to the glycosyl hydrolase 3 family
KCX77_01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCX77_01040	COG1263	PTS System
KCX77_01040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_01045	COG1737	Transcriptional regulator
KCX77_01050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KCX77_01055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_01060	COG1683	Conserved Protein
KCX77_01090	COG1595	DNA-templated transcription, initiation
KCX77_01095	COG5662	AntiSigma factor
KCX77_01100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCX77_01105	COG4856	YbbR-like protein
KCX77_01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCX77_01120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCX77_01125	COG3002	Belongs to the UPF0753 family
KCX77_01130	COG0288	reversible hydration of carbon dioxide
KCX77_01140	COG5609	conserved protein (DUF2294)
KCX77_01145	COG0640	Transcriptional regulator
KCX77_01150	COG2814	Major facilitator Superfamily
KCX77_01185	COG1132	(ABC) transporter
KCX77_01205	COG0076	glutamate decarboxylase activity
KCX77_01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_01220	COG2808	Putative FMN-binding domain
KCX77_01225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCX77_01235	COG1346	cytolysis
KCX77_01240	COG1380	Effector of murein hydrolase LrgA
KCX77_01245	COG1846	Transcriptional regulator
KCX77_01250	COG1113	amino acid transport
KCX77_01265	COG2602	Beta-lactamase
KCX77_01270	COG2124	cytochrome p450
KCX77_01280	COG0531	amino acid
KCX77_01285	COG0584	glycerophosphoryl diester phosphodiesterase
KCX77_01290	COG2271	Major facilitator Superfamily
KCX77_01300	COG0456	acetyltransferase
KCX77_01300	COG1846	Transcriptional regulator
KCX77_01305	COG2271	Major facilitator Superfamily
KCX77_01315	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_01320	COG0697	spore germination
KCX77_01325	COG0371	Dehydrogenase
KCX77_01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KCX77_01340	COG0596	Alpha beta hydrolase
KCX77_01345	COG1183	phosphatidylcholine synthase activity
KCX77_01350	COG0586	Pfam SNARE associated Golgi protein
KCX77_01355	COG0688	phosphatidylethanolamine metabolic process
KCX77_01360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCX77_01370	COG1404	Belongs to the peptidase S8 family
KCX77_01375	COG2312	Erythromycin esterase
KCX77_01385	COG1054	Belongs to the UPF0176 family
KCX77_01390	COG1301	dicarboxylic acid transport
KCX77_01400	COG0363	glucosamine-6-phosphate deaminase activity
KCX77_01405	COG2188	Transcriptional regulator
KCX77_01415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCX77_01420	COG0833	amino acid
KCX77_01425	COG2040	homocysteine
KCX77_01430	COG1115	amino acid carrier protein
KCX77_01435	COG2066	Belongs to the glutaminase family
KCX77_01440	COG4191	Histidine kinase
KCX77_01445	COG0784	Response regulator, receiver
KCX77_01450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCX77_01455	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_01460	COG2271	Major facilitator Superfamily
KCX77_01465	COG4948	Mandelate Racemase Muconate Lactonizing
KCX77_01470	COG2186	Transcriptional regulator
KCX77_01475	COG2721	sulfolactate sulfo-lyase activity
KCX77_01480	COG3173	Aminoglycoside phosphotransferase
KCX77_01495	COG0745	RESPONSE REGULATOR receiver
KCX77_01500	COG2205	protein histidine kinase activity
KCX77_01505	COG1131	(ABC) transporter
KCX77_01530	COG3773	Cell wall hydrolase
KCX77_01535	COG3540	Alkaline phosphatase
KCX77_01540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCX77_01545	COG0805	protein transport
KCX77_01555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCX77_01560	COG0477	Major facilitator Superfamily
KCX77_01565	COG1309	transcriptional regulator
KCX77_01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KCX77_01575	COG1405	negative regulation of cell septum assembly
KCX77_01575	COG3012	SEC-C Motif Domain Protein
KCX77_01590	COG1595	DNA-templated transcription, initiation
KCX77_01595	COG0735	belongs to the Fur family
KCX77_01600	COG1595	DNA-templated transcription, initiation
KCX77_01605	COG1876	peptidase activity
KCX77_01610	COG0457	Tetratricopeptide repeat
KCX77_01615	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_01620	COG0366	Alpha amylase catalytic
KCX77_01625	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCX77_01630	COG1121	(ABC) transporter
KCX77_01635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCX77_01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCX77_01645	COG2310	stress, protein
KCX77_01650	COG2310	stress, protein
KCX77_01655	COG2310	stress, protein
KCX77_01660	COG0861	Integral membrane protein TerC family
KCX77_01690	COG3853	Toxic anion resistance protein (TelA)
KCX77_01695	COG0477	Major facilitator Superfamily
KCX77_01700	COG4175	Glycine betaine
KCX77_01700	COG0517	IMP dehydrogenase activity
KCX77_01705	COG4176	ABC-type proline glycine betaine transport system permease component
KCX77_01710	COG2113	Glycine betaine
KCX77_01715	COG1473	amidohydrolase
KCX77_01720	COG1288	antiporter activity
KCX77_01730	COG0039	L-malate dehydrogenase activity
KCX77_01735	COG1620	l-lactate permease
KCX77_01740	COG2814	Major facilitator Superfamily
KCX77_01745	COG1846	Transcriptional regulator
KCX77_01750	COG1280	lysine exporter protein (LysE YggA)
KCX77_01755	COG3403	YqcI/YcgG family
KCX77_01760	COG1113	amino acid transport
KCX77_01765	COG3665	Urea carboxylase-associated protein
KCX77_01775	COG1660	Displays ATPase and GTPase activities
KCX77_01780	COG1082	Xylose isomerase domain protein TIM barrel
KCX77_01785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCX77_01795	COG3458	cephalosporin-C deacetylase activity
KCX77_01800	COG3541	Predicted nucleotidyltransferase
KCX77_01805	COG0506	proline dehydrogenase activity
KCX77_01810	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_01815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_01820	COG2508	Transcriptional regulator
KCX77_01825	COG3689	TIGRFAM TIGR03943 family protein
KCX77_01830	COG0701	Predicted permease
KCX77_01835	COG2267	carboxylic ester hydrolase activity
KCX77_01840	COG0492	ferredoxin-NADP+ reductase activity
KCX77_01845	COG1587	Uroporphyrinogen-III synthase
KCX77_01845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCX77_01850	COG2146	nitrite reductase [NAD(P)H] activity
KCX77_01855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCX77_01860	COG0243	molybdopterin cofactor binding
KCX77_01865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCX77_01870	COG2223	nitrite transmembrane transporter activity
KCX77_01875	COG1469	GTP cyclohydrolase I activity
KCX77_01880	COG1376	ErfK ybiS ycfS ynhG family protein
KCX77_01885	COG0523	cobalamin synthesis protein
KCX77_01890	COG0765	amino acid transport
KCX77_01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCX77_01900	COG1063	alcohol dehydrogenase
KCX77_01905	COG1714	RDD family
KCX77_01930	COG2723	6-phospho-beta-galactosidase activity
KCX77_01940	COG3209	COG3209 Rhs family protein
KCX77_01945	COG3290	protein histidine kinase activity
KCX77_01945	COG0840	transmembrane signaling receptor activity
KCX77_01950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KCX77_01955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KCX77_01960	COG1733	regulation of RNA biosynthetic process
KCX77_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_01980	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KCX77_01990	COG0697	spore germination
KCX77_01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_02005	COG2364	Membrane
KCX77_02010	COG1126	abc transporter atp-binding protein
KCX77_02015	COG0765	amino acid transport
KCX77_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCX77_02025	COG0583	DNA-binding transcription factor activity
KCX77_02030	COG0163	prenyltransferase activity
KCX77_02035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KCX77_02050	COG0596	Alpha beta hydrolase
KCX77_02055	COG3104	oligopeptide transport
KCX77_02060	COG5434	Belongs to the glycosyl hydrolase 28 family
KCX77_02070	COG0697	spore germination
KCX77_02080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KCX77_02085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCX77_02090	COG0456	acetyltransferase
KCX77_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCX77_02100	COG0765	amino acid transport
KCX77_02105	COG1126	abc transporter atp-binding protein
KCX77_02110	COG1473	amidohydrolase
KCX77_02115	COG2079	MmgE PrpD family protein
KCX77_02120	COG1136	(ABC) transporter
KCX77_02130	COG0457	Tetratricopeptide repeat
KCX77_02150	COG0527	aspartate kinase activity
KCX77_02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_02160	COG4605	iron ion homeostasis
KCX77_02165	COG4604	ABC transporter, ATP-binding protein
KCX77_02170	COG4607	ABC-type enterochelin transport system periplasmic component
KCX77_02175	COG2814	Major facilitator Superfamily
KCX77_02180	COG1309	transcriptional regulator
KCX77_02185	COG0457	Tetratricopeptide repeat
KCX77_02190	COG0778	Nitroreductase
KCX77_02195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KCX77_02200	COG0640	Transcriptional regulator
KCX77_02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCX77_02215	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_02220	COG4975	Glucose uptake
KCX77_02225	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_02230	COG4549	nuclear export factor GLE1
KCX77_02235	COG1276	copper resistance
KCX77_02235	COG2372	response to copper ion
KCX77_02240	COG1349	DNA-binding transcription factor activity
KCX77_02250	COG2213	PTS system mannitol-specific
KCX77_02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_02260	COG0246	Mannitol dehydrogenase
KCX77_02265	COG0412	Dienelactone hydrolase
KCX77_02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCX77_02285	COG0561	phosphatase activity
KCX77_02290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KCX77_02295	COG1914	H( )-stimulated, divalent metal cation uptake system
KCX77_02300	COG4336	lyase activity
KCX77_02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KCX77_02310	COG1984	allophanate hydrolase subunit 2
KCX77_02315	COG1414	Transcriptional regulator
KCX77_02320	COG2755	lipolytic protein G-D-S-L family
KCX77_02330	COG2329	Antibiotic biosynthesis monooxygenase
KCX77_02335	COG0768	penicillin binding
KCX77_02340	COG4989	oxidoreductase activity
KCX77_02345	COG3711	transcriptional antiterminator
KCX77_02350	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_02355	COG2226	methyltransferase
KCX77_02360	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_02365	COG1917	Cupin 2, conserved barrel domain protein
KCX77_02370	COG3871	stress protein (general stress protein 26)
KCX77_02385	COG2814	Major facilitator Superfamily
KCX77_02400	COG1522	sequence-specific DNA binding
KCX77_02405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCX77_02405	COG0551	DNA topoisomerase type I activity
KCX77_02410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KCX77_02415	COG3706	GGDEF domain
KCX77_02420	COG5298	Protein conserved in bacteria
KCX77_02425	COG1215	transferase activity, transferring glycosyl groups
KCX77_02435	COG0531	amino acid
KCX77_02445	COG0028	Belongs to the TPP enzyme family
KCX77_02455	COG1914	H( )-stimulated, divalent metal cation uptake system
KCX77_02460	COG2261	transglycosylase associated protein
KCX77_02465	COG4876	unkown
KCX77_02470	COG2217	Heavy metal translocating P-type atpase
KCX77_02475	COG3729	General stress protein
KCX77_02480	COG0662	Cupin 2, conserved barrel domain protein
KCX77_02485	COG2329	Antibiotic biosynthesis monooxygenase
KCX77_02490	COG3546	catalase activity
KCX77_02495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KCX77_02500	COG3290	protein histidine kinase activity
KCX77_02505	COG4565	transcriptional regulatory protein
KCX77_02510	COG1301	dicarboxylic acid transport
KCX77_02515	COG0628	permease
KCX77_02520	COG1131	(ABC) transporter
KCX77_02525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KCX77_02535	COG1960	acyl-CoA dehydrogenase activity
KCX77_02550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCX77_02555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_02560	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCX77_02565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCX77_02575	COG0513	Belongs to the DEAD box helicase family
KCX77_02580	COG3402	PFAM membrane-flanked domain
KCX77_02585	COG3428	Bacterial PH domain
KCX77_02590	COG0705	Rhomboid family
KCX77_02595	COG0736	holo-[acyl-carrier-protein] synthase activity
KCX77_02600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KCX77_02605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCX77_02610	COG0864	Transcriptional regulator
KCX77_02615	COG2337	Toxic component of a toxin-antitoxin (TA) module
KCX77_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_02625	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_02630	COG2172	sigma factor antagonist activity
KCX77_02635	COG2208	phosphoserine phosphatase activity
KCX77_02640	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_02645	COG2172	sigma factor antagonist activity
KCX77_02650	COG1191	sigma factor activity
KCX77_02655	COG2208	phosphoserine phosphatase activity
KCX77_02660	COG2183	response to ionizing radiation
KCX77_02670	COG3091	SprT-like family
KCX77_02720	COG1309	transcriptional regulator
KCX77_02725	COG0596	Alpha beta hydrolase
KCX77_02725	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCX77_02730	COG1902	pentaerythritol trinitrate reductase activity
KCX77_02735	COG0300	oxidoreductase activity
KCX77_02760	COG3048	D-serine ammonia-lyase activity
KCX77_02770	COG1316	TRANSCRIPTIONal
KCX77_02785	COG5002	protein histidine kinase activity
KCX77_02790	COG0745	RESPONSE REGULATOR receiver
KCX77_02810	COG3239	Fatty acid desaturase
KCX77_02820	COG1278	Cold shock
KCX77_02825	COG1329	Transcriptional regulator
KCX77_02830	COG2315	Protein conserved in bacteria
KCX77_02835	COG2364	Membrane
KCX77_02840	COG1846	Transcriptional regulator
KCX77_02845	COG0456	acetyltransferase
KCX77_02850	COG0697	spore germination
KCX77_02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_02865	COG2814	Major facilitator Superfamily
KCX77_02870	COG0789	Transcriptional regulator
KCX77_02870	COG4978	Transcriptional regulator
KCX77_02880	COG0697	spore germination
KCX77_02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_02890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_02895	COG2814	Major facilitator Superfamily
KCX77_02900	COG1309	transcriptional regulator
KCX77_02910	COG0640	Transcriptional regulator
KCX77_02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KCX77_02920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCX77_02930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_02940	COG1846	Transcriptional regulator
KCX77_02945	COG2409	Drug exporters of the RND superfamily
KCX77_02945	COG1033	growth of symbiont in host cell
KCX77_02965	COG3711	transcriptional antiterminator
KCX77_02965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_02970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_02970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCX77_02970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCX77_02975	COG1482	cell wall glycoprotein biosynthetic process
KCX77_02985	COG0697	spore germination
KCX77_02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCX77_03000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCX77_03005	COG1522	sequence-specific DNA binding
KCX77_03015	COG2323	membrane
KCX77_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_03025	COG1309	transcriptional regulator
KCX77_03040	COG0673	inositol 2-dehydrogenase activity
KCX77_03045	COG1609	Transcriptional regulator
KCX77_03050	COG2814	Major facilitator Superfamily
KCX77_03055	COG1082	Xylose isomerase domain protein TIM barrel
KCX77_03060	COG0071	Belongs to the small heat shock protein (HSP20) family
KCX77_03065	COG0488	(ABC) transporter
KCX77_03070	COG0596	Alpha beta hydrolase
KCX77_03085	COG2602	Beta-lactamase
KCX77_03095	COG2814	Major facilitator Superfamily
KCX77_03105	COG1388	LysM domain
KCX77_03105	COG3858	chitin binding
KCX77_03110	COG1819	glycosyl
KCX77_03125	COG1785	Belongs to the alkaline phosphatase family
KCX77_03135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCX77_03140	COG0517	IMP dehydrogenase activity
KCX77_03140	COG1125	glycine betaine transport
KCX77_03145	COG1174	glycine betaine transport
KCX77_03150	COG5434	Belongs to the glycosyl hydrolase 28 family
KCX77_03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_03170	COG2814	Major facilitator Superfamily
KCX77_03175	COG2186	Transcriptional regulator
KCX77_03180	COG2807	transmembrane transport
KCX77_03195	COG1378	Sugar-specific transcriptional regulator TrmB
KCX77_03235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCX77_03240	COG0802	atpase or kinase
KCX77_03245	COG1214	PFAM Peptidase M22, glycoprotease
KCX77_03250	COG0456	acetyltransferase
KCX77_03255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCX77_03260	COG0488	(ABC) transporter
KCX77_03265	COG0315	cyclic pyranopterin monophosphate synthase activity
KCX77_03275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCX77_03280	COG0805	protein transport
KCX77_03290	COG1266	CAAX protease self-immunity
KCX77_03305	COG0582	viral genome integration into host DNA
KCX77_03310	COG2856	Zn peptidase
KCX77_03315	COG1396	sequence-specific DNA binding
KCX77_03330	COG3645	SOS response
KCX77_03330	COG3646	Phage regulatory protein
KCX77_03365	COG3935	DnaD domain protein
KCX77_03370	COG1484	DNA-dependent DNA replication
KCX77_03380	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KCX77_03425	COG1595	DNA-templated transcription, initiation
KCX77_03520	COG5280	Phage tail tape measure protein TP901
KCX77_03520	COG3953	SLT domain
KCX77_03530	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCX77_03535	COG5434	Belongs to the glycosyl hydrolase 28 family
KCX77_03560	COG4824	toxin secretion phage lysis holin
KCX77_03565	COG5632	N-Acetylmuramoyl-L-alanine amidase
KCX77_03565	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_03565	COG1388	LysM domain
KCX77_03605	COG0582	viral genome integration into host DNA
KCX77_03610	COG2856	Zn peptidase
KCX77_03615	COG1396	sequence-specific DNA binding
KCX77_03630	COG3645	SOS response
KCX77_03630	COG3646	Phage regulatory protein
KCX77_03665	COG3935	DnaD domain protein
KCX77_03670	COG1484	DNA-dependent DNA replication
KCX77_03680	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KCX77_03725	COG1595	DNA-templated transcription, initiation
KCX77_03820	COG3953	SLT domain
KCX77_03820	COG5280	Phage tail tape measure protein TP901
KCX77_03830	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCX77_03835	COG5434	Belongs to the glycosyl hydrolase 28 family
KCX77_03860	COG4824	toxin secretion phage lysis holin
KCX77_03865	COG1388	LysM domain
KCX77_03865	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_03865	COG5632	N-Acetylmuramoyl-L-alanine amidase
KCX77_03935	COG0457	Tetratricopeptide repeat
KCX77_03940	COG1063	alcohol dehydrogenase
KCX77_03945	COG2211	Major facilitator Superfamily
KCX77_03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCX77_03960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCX77_03965	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KCX77_03970	COG4260	virion core protein, lumpy skin disease virus
KCX77_03980	COG1595	DNA-templated transcription, initiation
KCX77_03990	COG0778	Nitroreductase
KCX77_03995	COG1846	Transcriptional regulator
KCX77_04000	COG2814	Major facilitator Superfamily
KCX77_04005	COG1063	alcohol dehydrogenase
KCX77_04010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KCX77_04015	COG0823	Involved in the tonB-independent uptake of proteins
KCX77_04025	COG2267	carboxylic ester hydrolase activity
KCX77_04035	COG2132	Multicopper oxidase
KCX77_04040	COG1113	amino acid transport
KCX77_04050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCX77_04055	COG0714	Associated with various cellular activities
KCX77_04060	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KCX77_04065	COG1305	Transglutaminase-like
KCX77_04070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCX77_04070	COG0519	Catalyzes the synthesis of GMP from XMP
KCX77_04075	COG2252	PERMEase
KCX77_04080	COG3064	Membrane
KCX77_04090	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KCX77_04100	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCX77_04105	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCX77_04110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCX77_04115	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KCX77_04120	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCX77_04125	COG0047	phosphoribosylformylglycinamidine synthase activity
KCX77_04130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCX77_04135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCX77_04145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCX77_04150	COG0138	bifunctional purine biosynthesis protein purh
KCX77_04155	COG0151	Belongs to the GarS family
KCX77_04160	COG1522	sequence-specific DNA binding
KCX77_04165	COG0531	amino acid
KCX77_04175	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KCX77_04180	COG1470	cell adhesion involved in biofilm formation
KCX77_04185	COG4496	protein, YerC YecD
KCX77_04190	COG0069	glutamate synthase activity
KCX77_04195	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KCX77_04200	COG0210	DNA helicase
KCX77_04205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCX77_04210	COG4851	CamS sex pheromone cAM373 precursor
KCX77_04215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCX77_04220	COG1285	pathogenesis
KCX77_04225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_04235	COG0154	amidase activity
KCX77_04245	COG1309	transcriptional regulator
KCX77_04250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCX77_04255	COG1597	lipid kinase activity
KCX77_04260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCX77_04270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KCX77_04280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KCX77_04300	COG5444	nuclease activity
KCX77_04310	COG0457	Tetratricopeptide repeat
KCX77_04335	COG3546	catalase activity
KCX77_04340	COG0454	-acetyltransferase
KCX77_04350	COG5578	integral membrane protein
KCX77_04355	COG2972	Histidine kinase
KCX77_04360	COG2207	Transcriptional regulator
KCX77_04360	COG4753	response regulator
KCX77_04365	COG1653	transport
KCX77_04370	COG1175	transmembrane transport
KCX77_04375	COG0395	ABC-type sugar transport system, permease component
KCX77_04380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KCX77_04385	COG2207	Transcriptional regulator
KCX77_04390	COG2755	lipolytic protein G-D-S-L family
KCX77_04400	COG5578	integral membrane protein
KCX77_04405	COG3401	FG-GAP repeat protein
KCX77_04410	COG3401	FG-GAP repeat protein
KCX77_04415	COG0667	Aldo Keto reductase
KCX77_04420	COG2755	lipolytic protein G-D-S-L family
KCX77_04425	COG1874	Beta-galactosidase
KCX77_04435	COG1653	transport
KCX77_04440	COG4209	transmembrane transport
KCX77_04445	COG0395	ABC-type sugar transport system, permease component
KCX77_04450	COG1486	melibiose metabolic process
KCX77_04455	COG2323	membrane
KCX77_04460	COG2329	Antibiotic biosynthesis monooxygenase
KCX77_04465	COG0346	lactoylglutathione lyase activity
KCX77_04470	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_04475	COG5583	Uncharacterized small protein (DUF2292)
KCX77_04480	COG0196	riboflavin kinase activity
KCX77_04485	COG0670	Belongs to the BI1 family
KCX77_04495	COG2124	cytochrome p450
KCX77_04495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCX77_04510	COG1131	(ABC) transporter
KCX77_04520	COG1368	sulfuric ester hydrolase activity
KCX77_04525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCX77_04530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_04535	COG1442	glycosyl transferase family 8
KCX77_04540	COG1216	Glycosyl transferase, family 2
KCX77_04545	COG1442	glycosyl transferase family 8
KCX77_04550	COG2223	nitrite transmembrane transporter activity
KCX77_04555	COG0531	amino acid
KCX77_04560	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_04565	COG0840	transmembrane signaling receptor activity
KCX77_04570	COG0457	Tetratricopeptide repeat
KCX77_04570	COG0463	Glycosyl transferase, family 2
KCX77_04575	COG0488	(ABC) transporter
KCX77_04580	COG0789	Transcriptional regulator
KCX77_04585	COG2814	Major facilitator Superfamily
KCX77_04590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_04595	COG0488	(ABC) transporter
KCX77_04600	COG0513	Belongs to the DEAD box helicase family
KCX77_04605	COG2130	NADP-dependent
KCX77_04610	COG1120	ATPase activity
KCX77_04615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_04625	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCX77_04640	COG3866	Pectate lyase
KCX77_04650	COG0471	metal ion transport
KCX77_04655	COG3290	protein histidine kinase activity
KCX77_04660	COG4565	transcriptional regulatory protein
KCX77_04665	COG3181	Tripartite tricarboxylate transporter family receptor
KCX77_04670	COG2851	Citrate transporter
KCX77_04675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_04680	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KCX77_04685	COG1254	Belongs to the acylphosphatase family
KCX77_04690	COG2258	MOSC domain
KCX77_04710	COG0024	Methionine aminopeptidase
KCX77_04715	COG1263	PTS System
KCX77_04715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_04720	COG1368	sulfuric ester hydrolase activity
KCX77_04730	COG1115	amino acid carrier protein
KCX77_04735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_04735	COG1263	PTS System
KCX77_04740	COG0366	Alpha amylase catalytic
KCX77_04745	COG2188	Transcriptional regulator
KCX77_04750	COG0778	Nitroreductase
KCX77_04755	COG0737	Belongs to the 5'-nucleotidase family
KCX77_04760	COG0693	protein deglycase activity
KCX77_04765	COG1609	Transcriptional regulator
KCX77_04770	COG2814	Major facilitator Superfamily
KCX77_04775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCX77_04785	COG2814	Major facilitator Superfamily
KCX77_04790	COG4840	Belongs to the UPF0435 family
KCX77_04795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCX77_04800	COG4980	gas vesicle protein
KCX77_04805	COG1295	ribonuclease BN
KCX77_04810	COG0477	Major facilitator Superfamily
KCX77_04815	COG0387	Pfam Sodium calcium exchanger
KCX77_04825	COG0668	transmembrane transport
KCX77_04830	COG0535	radical SAM domain protein
KCX77_04840	COG0726	polysaccharide deacetylase
KCX77_04845	COG2084	Dehydrogenase
KCX77_04855	COG0598	Magnesium transport protein CorA
KCX77_04860	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCX77_04870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCX77_04875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCX77_04880	COG4637	Psort location Cytoplasmic, score
KCX77_04885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCX77_04890	COG0022	dehydrogenase e1 component
KCX77_04895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCX77_04900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCX77_04905	COG3284	Transcriptional regulator
KCX77_04915	COG1742	UPF0060 membrane protein
KCX77_04935	COG4842	Belongs to the WXG100 family
KCX77_04940	COG1486	melibiose metabolic process
KCX77_04945	COG1737	Transcriptional regulator
KCX77_04950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_04950	COG1263	PTS System
KCX77_04955	COG5434	Belongs to the glycosyl hydrolase 28 family
KCX77_04960	COG1132	(ABC) transporter
KCX77_04965	COG1132	(ABC) transporter
KCX77_04970	COG2259	Doxx family
KCX77_04975	COG2514	catechol 2,3-dioxygenase activity
KCX77_04980	COG4585	Histidine kinase
KCX77_04985	COG2197	response regulator
KCX77_04990	COG1131	(ABC) transporter
KCX77_04995	COG0842	Transport permease protein
KCX77_04995	COG1511	domain protein
KCX77_05000	COG0842	Transport permease protein
KCX77_05005	COG1695	Transcriptional regulator
KCX77_05010	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KCX77_05015	COG2732	(Barnase) inhibitor
KCX77_05020	COG0604	alcohol dehydrogenase
KCX77_05025	COG2318	DinB family
KCX77_05030	COG2814	Major facilitator Superfamily
KCX77_05035	COG1846	Transcriptional regulator
KCX77_05040	COG0392	lysyltransferase activity
KCX77_05040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCX77_05045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_05050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_05055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_05060	COG0384	phenazine biosynthesis protein PhzF
KCX77_05065	COG0778	Nitroreductase
KCX77_05080	COG1090	epimerase
KCX77_05085	COG2137	regulation of response to DNA damage stimulus
KCX77_05095	COG2814	Major facilitator Superfamily
KCX77_05110	COG3103	Sh3 type 3 domain protein
KCX77_05115	COG5658	integral membrane protein
KCX77_05120	COG0596	Alpha beta hydrolase
KCX77_05125	COG0463	Glycosyl transferase, family 2
KCX77_05130	COG4485	Bacterial membrane protein, YfhO
KCX77_05135	COG1988	membrane-bound metal-dependent
KCX77_05140	COG1194	a g-specific adenine glycosylase
KCX77_05150	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_05165	COG3557	Belongs to the UPF0374 family
KCX77_05170	COG1132	(ABC) transporter
KCX77_05175	COG4129	membrane
KCX77_05180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCX77_05185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCX77_05190	COG0735	belongs to the Fur family
KCX77_05300	COG1063	alcohol dehydrogenase
KCX77_05305	COG5577	PFAM Coat F domain
KCX77_05315	COG4326	sporulation control protein
KCX77_05325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KCX77_05335	COG0753	catalase activity
KCX77_05340	COG1116	anion transmembrane transporter activity
KCX77_05345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCX77_05350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCX77_05360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCX77_05370	COG1476	TRANSCRIPTIONal
KCX77_05380	COG3382	B3 4 domain protein
KCX77_05385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCX77_05395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KCX77_05400	COG0789	Transcriptional regulator
KCX77_05405	COG1664	Polymer-forming cytoskeletal
KCX77_05410	COG1664	Polymer-forming cytoskeletal
KCX77_05415	COG2766	serine protein kinase
KCX77_05420	COG2718	Belongs to the UPF0229 family
KCX77_05425	COG1846	Transcriptional regulator
KCX77_05430	COG1566	PFAM secretion protein HlyD family protein
KCX77_05435	COG2814	Major facilitator Superfamily
KCX77_05440	COG0655	NAD(P)H dehydrogenase (quinone) activity
KCX77_05455	COG1725	Transcriptional regulator
KCX77_05460	COG1131	(ABC) transporter
KCX77_05465	COG1131	(ABC) transporter
KCX77_05470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KCX77_05475	COG1278	Cold shock
KCX77_05485	COG1464	Belongs to the NlpA lipoprotein family
KCX77_05490	COG3706	GGDEF domain
KCX77_05495	COG1823	symporter activity
KCX77_05515	COG5577	PFAM Coat F domain
KCX77_05525	COG0737	Belongs to the 5'-nucleotidase family
KCX77_05525	COG1525	nuclease
KCX77_05525	COG4085	toxin activity
KCX77_05530	COG3764	Sortase (surface protein transpeptidase)
KCX77_05535	COG0564	pseudouridine synthase activity
KCX77_05545	COG0517	IMP dehydrogenase activity
KCX77_05550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCX77_05555	COG3153	acetyltransferase
KCX77_05555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCX77_05565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCX77_05570	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KCX77_05575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCX77_05580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KCX77_05585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KCX77_05590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCX77_05595	COG2203	Gaf domain
KCX77_05595	COG4585	Histidine kinase
KCX77_05600	COG2197	response regulator
KCX77_05605	COG0431	NADPH-dependent FMN reductase
KCX77_05620	COG0791	NLP P60 protein
KCX77_05620	COG1388	LysM domain
KCX77_05625	COG1959	2 iron, 2 sulfur cluster binding
KCX77_05630	COG0668	transmembrane transport
KCX77_05635	COG2719	SpoVR family
KCX77_05640	COG1785	Belongs to the alkaline phosphatase family
KCX77_05645	COG0791	NLP P60 protein
KCX77_05645	COG1388	LysM domain
KCX77_05650	COG0583	DNA-binding transcription factor activity
KCX77_05655	COG0372	Belongs to the citrate synthase family
KCX77_05660	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_05665	COG0531	amino acid
KCX77_05670	COG0733	neurotransmitter:sodium symporter activity
KCX77_05680	COG0456	acetyltransferase
KCX77_05685	COG0833	amino acid
KCX77_05690	COG4187	Peptidase family M20/M25/M40
KCX77_05695	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_05700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCX77_05715	COG1595	DNA-templated transcription, initiation
KCX77_05720	COG0667	Aldo Keto reductase
KCX77_05725	COG0204	Acyl-transferase
KCX77_05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCX77_05735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_05740	COG1253	flavin adenine dinucleotide binding
KCX77_05745	COG0789	Transcriptional regulator
KCX77_05750	COG1253	flavin adenine dinucleotide binding
KCX77_05755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCX77_05760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCX77_05765	COG0584	glycerophosphoryl diester phosphodiesterase
KCX77_05775	COG0668	transmembrane transport
KCX77_05780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KCX77_05785	COG0726	polysaccharide deacetylase
KCX77_05790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCX77_05795	COG1757	Na H antiporter
KCX77_05800	COG0589	response to stress
KCX77_05805	COG1132	(ABC) transporter
KCX77_05810	COG1132	(ABC) transporter
KCX77_05815	COG0702	epimerase
KCX77_05835	COG0189	ligase activity
KCX77_05840	COG0189	ligase activity
KCX77_05845	COG4399	Belongs to the UPF0754 family
KCX77_05855	COG4335	DNA alkylation repair
KCX77_05860	COG0561	phosphatase activity
KCX77_05865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCX77_05875	COG0475	glutathione-regulated potassium exporter activity
KCX77_05880	COG0490	domain, Protein
KCX77_05890	COG1024	Enoyl-CoA hydratase
KCX77_05900	COG4152	abc transporter atp-binding protein
KCX77_05905	COG1668	transmembrane transport
KCX77_05910	COG0420	3'-5' exonuclease activity
KCX77_05915	COG4717	serine-type aminopeptidase activity
KCX77_05920	COG3481	metal-dependent phosphohydrolase, HD sub domain
KCX77_05930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCX77_05965	COG4980	gas vesicle protein
KCX77_05980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCX77_05985	COG0537	adenosine 5'-monophosphoramidase activity
KCX77_05990	COG1131	(ABC) transporter
KCX77_05995	COG4473	ABC transporter
KCX77_06005	COG1473	amidohydrolase
KCX77_06010	COG3069	C4-dicarboxylate transmembrane transporter activity
KCX77_06015	COG2329	Antibiotic biosynthesis monooxygenase
KCX77_06020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCX77_06025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCX77_06030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCX77_06035	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KCX77_06040	COG1309	transcriptional regulator
KCX77_06045	COG1511	domain protein
KCX77_06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCX77_06060	COG1363	Peptidase, m42
KCX77_06065	COG1301	dicarboxylic acid transport
KCX77_06075	COG1234	tRNA 3'-trailer cleavage
KCX77_06080	COG0095	Lipoate-protein ligase
KCX77_06085	COG0702	epimerase
KCX77_06090	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_06100	COG0501	Belongs to the peptidase M48B family
KCX77_06105	COG1404	Belongs to the peptidase S8 family
KCX77_06110	COG0456	acetyltransferase
KCX77_06115	COG0604	alcohol dehydrogenase
KCX77_06120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KCX77_06125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_06130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_06135	COG0406	alpha-ribazole phosphatase activity
KCX77_06140	COG0183	Belongs to the thiolase family
KCX77_06150	COG1960	acyl-CoA dehydrogenase activity
KCX77_06155	COG2084	Dehydrogenase
KCX77_06160	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_06165	COG1024	Enoyl-CoA hydratase
KCX77_06175	COG0840	transmembrane signaling receptor activity
KCX77_06180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCX77_06180	COG0723	plastoquinol--plastocyanin reductase activity
KCX77_06185	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_06195	COG4903	ComK protein
KCX77_06205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_06220	COG0398	Pfam SNARE associated Golgi protein
KCX77_06225	COG0681	Belongs to the peptidase S26 family
KCX77_06230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCX77_06235	COG1846	Transcriptional regulator
KCX77_06240	COG3180	Ammonia monooxygenase
KCX77_06250	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KCX77_06255	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCX77_06260	COG1074	ATP-dependent DNA helicase activity
KCX77_06265	COG0420	3'-5' exonuclease activity
KCX77_06270	COG0419	ATPase involved in DNA repair
KCX77_06275	COG1403	HNH endonuclease
KCX77_06310	COG2311	Membrane
KCX77_06320	COG5337	Spore coat protein CotH
KCX77_06325	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCX77_06335	COG1404	Belongs to the peptidase S8 family
KCX77_06345	COG0367	asparagine synthase
KCX77_06350	COG1562	ergosterol biosynthetic process
KCX77_06355	COG0534	Mate efflux family protein
KCX77_06360	COG2207	Transcriptional regulator
KCX77_06360	COG1917	Cupin 2, conserved barrel domain protein
KCX77_06365	COG0109	protoheme IX farnesyltransferase activity
KCX77_06370	COG1609	Transcriptional regulator
KCX77_06375	COG0673	inositol 2-dehydrogenase activity
KCX77_06380	COG2318	DinB family
KCX77_06395	COG1357	PFAM Pentapeptide repeats (8 copies)
KCX77_06405	COG2267	carboxylic ester hydrolase activity
KCX77_06410	COG0529	Catalyzes the synthesis of activated sulfate
KCX77_06415	COG2046	Belongs to the sulfate adenylyltransferase family
KCX77_06420	COG0175	sulfate reduction
KCX77_06425	COG2045	Belongs to the ComB family
KCX77_06430	COG1809	phosphosulfolactate synthase activity
KCX77_06435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_06440	COG4948	Mandelate Racemase Muconate Lactonizing
KCX77_06445	COG2814	Major facilitator Superfamily
KCX77_06455	COG2153	protein acetylation
KCX77_06460	COG0646	methionine synthase
KCX77_06460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCX77_06470	COG2996	Protein conserved in bacteria
KCX77_06490	COG1307	EDD domain protein, DegV family
KCX77_06495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_06515	COG0561	phosphatase activity
KCX77_06520	COG1073	alpha beta
KCX77_06525	COG2151	metal-sulfur cluster biosynthetic enzyme
KCX77_06535	COG0277	FAD linked oxidase domain protein
KCX77_06540	COG2271	Major facilitator Superfamily
KCX77_06545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCX77_06550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCX77_06560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCX77_06565	COG0505	Belongs to the CarA family
KCX77_06570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCX77_06575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCX77_06590	COG2267	carboxylic ester hydrolase activity
KCX77_06600	COG1744	ABC transporter substrate-binding protein PnrA-like
KCX77_06615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCX77_06620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCX77_06625	COG5504	Zn-dependent protease
KCX77_06630	COG0444	Belongs to the ABC transporter superfamily
KCX77_06635	COG4608	Belongs to the ABC transporter superfamily
KCX77_06645	COG0601	transmembrane transport
KCX77_06650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCX77_06660	COG0180	Tryptophanyl-tRNA synthetase
KCX77_06665	COG4166	transmembrane transport
KCX77_06670	COG0601	transmembrane transport
KCX77_06675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCX77_06680	COG0444	Belongs to the ABC transporter superfamily
KCX77_06685	COG4608	Belongs to the ABC transporter superfamily
KCX77_06695	COG0456	acetyltransferase
KCX77_06700	COG1393	Belongs to the ArsC family
KCX77_06705	COG0861	Integral membrane protein TerC family
KCX77_06715	COG4862	establishment of competence for transformation
KCX77_06720	COG4469	Competence protein
KCX77_06725	COG1164	Oligoendopeptidase f
KCX77_06735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCX77_06740	COG2346	COG2346, Truncated hemoglobins
KCX77_06745	COG0741	lytic transglycosylase activity
KCX77_06750	COG4116	CYTH
KCX77_06760	COG2357	RelA SpoT domain protein
KCX77_06765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCX77_06770	COG0564	pseudouridine synthase activity
KCX77_06780	COG0475	glutathione-regulated potassium exporter activity
KCX77_06780	COG0569	domain protein
KCX77_06785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KCX77_06790	COG0352	thiamine-phosphate diphosphorylase activity
KCX77_06795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCX77_06800	COG2104	thiamine diphosphate biosynthetic process
KCX77_06805	COG2022	thiamine diphosphate biosynthetic process
KCX77_06810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCX77_06815	COG0351	phosphomethylpyrimidine kinase
KCX77_06820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KCX77_06875	COG0210	DNA helicase
KCX77_06885	COG2153	protein acetylation
KCX77_06895	COG2382	esterase
KCX77_06900	COG0626	cystathionine gamma-synthase activity
KCX77_06905	COG0626	cystathionine gamma-synthase activity
KCX77_06910	COG5505	Protein of unknown function (DUF819)
KCX77_06925	COG1846	Transcriptional regulator
KCX77_06930	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_06935	COG5444	nuclease activity
KCX77_06945	COG0457	Tetratricopeptide repeat
KCX77_06955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCX77_06985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KCX77_07010	COG3209	COG3209 Rhs family protein
KCX77_07015	COG1285	pathogenesis
KCX77_07035	COG0726	polysaccharide deacetylase
KCX77_07045	COG2205	protein histidine kinase activity
KCX77_07055	COG3383	formate dehydrogenase (NAD+) activity
KCX77_07060	COG2427	Protein of unknown function (DUF1641)
KCX77_07070	COG1051	belongs to the nudix hydrolase family
KCX77_07080	COG2124	cytochrome p450
KCX77_07085	COG1819	glycosyl
KCX77_07105	COG1587	Uroporphyrinogen-III synthase
KCX77_07110	COG0390	transport system, permease component
KCX77_07115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCX77_07120	COG0697	spore germination
KCX77_07125	COG4297	protein containing double-stranded beta helix domain
KCX77_07135	COG1252	NADH dehydrogenase
KCX77_07140	COG1904	glucuronate isomerase
KCX77_07145	COG2211	Major facilitator Superfamily
KCX77_07150	COG1609	Transcriptional regulator
KCX77_07155	COG0246	Mannitol dehydrogenase
KCX77_07160	COG2721	sulfolactate sulfo-lyase activity
KCX77_07165	COG0730	response to heat
KCX77_07170	COG2318	DinB family
KCX77_07175	COG0457	Tetratricopeptide repeat
KCX77_07190	COG1388	LysM domain
KCX77_07190	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_07190	COG5632	N-Acetylmuramoyl-L-alanine amidase
KCX77_07200	COG4195	phage-related replication protein
KCX77_07205	COG2856	Zn peptidase
KCX77_07210	COG1396	sequence-specific DNA binding
KCX77_07220	COG1522	sequence-specific DNA binding
KCX77_07225	COG1484	DNA-dependent DNA replication
KCX77_07245	COG1595	DNA-templated transcription, initiation
KCX77_07250	COG3728	DNA packaging
KCX77_07250	COG5484	DNA packaging
KCX77_07255	COG1783	phage Terminase large subunit
KCX77_07260	COG5518	Phage portal protein
KCX77_07265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KCX77_07270	COG4653	Phage capsid family
KCX77_07320	COG3953	SLT domain
KCX77_07320	COG5412	phage tail tape measure protein
KCX77_07325	COG1652	LysM domain
KCX77_07330	COG4193	domain, Protein
KCX77_07345	COG3628	GPW Gp25 family protein
KCX77_07350	COG3299	homolog of phage Mu protein gp47
KCX77_07355	COG3778	Protein conserved in bacteria
KCX77_07395	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_07395	COG5632	N-Acetylmuramoyl-L-alanine amidase
KCX77_07415	COG0306	phosphate transporter
KCX77_07420	COG1392	Phosphate transport regulator
KCX77_07425	COG0531	amino acid
KCX77_07430	COG0346	lactoylglutathione lyase activity
KCX77_07435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCX77_07440	COG0463	Glycosyl transferase, family 2
KCX77_07450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCX77_07455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCX77_07460	COG2362	D-Aminopeptidase
KCX77_07465	COG0601	transmembrane transport
KCX77_07470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCX77_07475	COG0444	Belongs to the ABC transporter superfamily
KCX77_07480	COG4166	transmembrane transport
KCX77_07485	COG1619	proteins homologs of microcin C7 resistance protein MccF
KCX77_07490	COG4948	Mandelate Racemase Muconate Lactonizing
KCX77_07495	COG0791	NLP P60 protein
KCX77_07500	COG4608	Belongs to the ABC transporter superfamily
KCX77_07505	COG2706	6-phosphogluconolactonase activity
KCX77_07510	COG1834	amidinotransferase
KCX77_07515	COG1607	acyl-coa hydrolase
KCX77_07520	COG2323	membrane
KCX77_07525	COG1695	Transcriptional regulator
KCX77_07540	COG2318	DinB family
KCX77_07545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_07550	COG2076	Multidrug Resistance protein
KCX77_07555	COG2076	Multidrug Resistance protein
KCX77_07560	COG0788	formyltetrahydrofolate deformylase activity
KCX77_07565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCX77_07570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCX77_07575	COG1764	response to oxidative stress
KCX77_07580	COG1846	Transcriptional regulator
KCX77_07585	COG1764	response to oxidative stress
KCX77_07600	COG0457	Tetratricopeptide repeat
KCX77_07600	COG0463	Glycosyl transferase, family 2
KCX77_07610	COG0590	tRNA wobble adenosine to inosine editing
KCX77_07620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCX77_07625	COG1404	Belongs to the peptidase S8 family
KCX77_07630	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_07635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCX77_07640	COG1122	ATPase activity
KCX77_07645	COG4721	ABC-type cobalt transport system, permease component
KCX77_07655	COG0745	RESPONSE REGULATOR receiver
KCX77_07660	COG3850	Histidine kinase
KCX77_07660	COG5002	protein histidine kinase activity
KCX77_07665	COG3212	peptidase
KCX77_07670	COG3212	peptidase
KCX77_07680	COG2239	Acts as a magnesium transporter
KCX77_07685	COG0789	Transcriptional regulator
KCX77_07700	COG1846	Transcriptional regulator
KCX77_07705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCX77_07710	COG0726	polysaccharide deacetylase
KCX77_07715	COG1408	metallophosphoesterase
KCX77_07730	COG0463	Glycosyl transferase, family 2
KCX77_07735	COG1793	dna ligase
KCX77_07735	COG3285	dna ligase
KCX77_07740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KCX77_07750	COG3300	MHYT domain
KCX77_07750	COG5001	Diguanylate cyclase
KCX77_07755	COG5001	Diguanylate cyclase
KCX77_07755	COG3300	MHYT domain
KCX77_07765	COG0586	Pfam SNARE associated Golgi protein
KCX77_07770	COG0861	Integral membrane protein TerC family
KCX77_07775	COG1191	sigma factor activity
KCX77_07795	COG0501	Belongs to the peptidase M48B family
KCX77_07800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KCX77_07805	COG2323	membrane
KCX77_07820	COG3594	Acyltransferase
KCX77_07825	COG5002	protein histidine kinase activity
KCX77_07830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCX77_07840	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KCX77_07845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCX77_07850	COG0436	Aminotransferase
KCX77_07855	COG1850	ribulose-bisphosphate carboxylase activity
KCX77_07865	COG0235	Class ii aldolase
KCX77_07870	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCX77_07875	COG3339	Conserved Protein
KCX77_07890	COG3852	Histidine kinase
KCX77_07895	COG1846	Transcriptional regulator
KCX77_07900	COG1360	Flagellar Motor Protein
KCX77_07905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCX77_07910	COG0542	response to heat
KCX77_07915	COG3949	Membrane
KCX77_07930	COG0720	synthase
KCX77_07935	COG0602	queuosine metabolic process
KCX77_07940	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KCX77_07945	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_07955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_07960	COG4873	Protein conserved in bacteria
KCX77_07970	COG3773	Cell wall hydrolase
KCX77_07975	COG2244	polysaccharide biosynthetic process
KCX77_07980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_07985	COG2217	Heavy metal translocating P-type atpase
KCX77_07995	COG0006	proline dipeptidase activity
KCX77_08000	COG1609	Transcriptional regulator
KCX77_08005	COG3711	transcriptional antiterminator
KCX77_08010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_08010	COG2190	(PTS) system
KCX77_08010	COG1263	PTS System
KCX77_08015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_08020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCX77_08030	COG1533	DNA photolyase activity
KCX77_08035	COG0456	acetyltransferase
KCX77_08040	COG0840	transmembrane signaling receptor activity
KCX77_08045	COG2084	Dehydrogenase
KCX77_08050	COG2340	Cysteine-rich secretory protein family
KCX77_08055	COG0768	penicillin binding
KCX77_08060	COG4191	Histidine kinase
KCX77_08065	COG0436	Aminotransferase
KCX77_08075	COG0784	Response regulator, receiver
KCX77_08075	COG0835	chemotaxis
KCX77_08085	COG2814	Major facilitator Superfamily
KCX77_08090	COG1376	ErfK ybiS ycfS ynhG family protein
KCX77_08095	COG1408	metallophosphoesterase
KCX77_08100	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_08105	COG2200	EAL domain
KCX77_08110	COG3546	catalase activity
KCX77_08115	COG4703	Protein of unknown function (DUF1797)
KCX77_08120	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KCX77_08130	COG0517	IMP dehydrogenase activity
KCX77_08135	COG0583	DNA-binding transcription factor activity
KCX77_08140	COG0716	FMN binding
KCX77_08150	COG0716	FMN binding
KCX77_08155	COG2171	N-acyltransferase activity
KCX77_08160	COG1473	amidohydrolase
KCX77_08170	COG0668	transmembrane transport
KCX77_08175	COG0450	alkyl hydroperoxide reductase
KCX77_08180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_08195	COG0746	molybdenum cofactor guanylyltransferase activity
KCX77_08200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCX77_08205	COG0303	'Molybdopterin
KCX77_08210	COG1763	Mo-molybdopterin cofactor biosynthetic process
KCX77_08215	COG0314	molybdopterin synthase activity
KCX77_08220	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCX77_08225	COG1132	(ABC) transporter
KCX77_08230	COG1132	(ABC) transporter
KCX77_08240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCX77_08245	COG1136	(ABC) transporter
KCX77_08250	COG0577	efflux transmembrane transporter activity
KCX77_08255	COG1349	DNA-binding transcription factor activity
KCX77_08260	COG1105	Belongs to the carbohydrate kinase PfkB family
KCX77_08265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCX77_08265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCX77_08265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_08270	COG0681	Belongs to the peptidase S26 family
KCX77_08280	COG0488	(ABC) transporter
KCX77_08285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCX77_08290	COG2309	aminopeptidase activity
KCX77_08300	COG1077	Cell shape determining protein MreB Mrl
KCX77_08305	COG2002	toxin-antitoxin pair type II binding
KCX77_08310	COG3852	Histidine kinase
KCX77_08315	COG2105	PFAM AIG2 family protein
KCX77_08315	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KCX77_08320	COG0569	domain protein
KCX77_08325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KCX77_08330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCX77_08340	COG0561	phosphatase activity
KCX77_08345	COG0242	peptide deformylase activity
KCX77_08355	COG0497	DNA recombination
KCX77_08360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCX77_08365	COG0022	dehydrogenase e1 component
KCX77_08370	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCX77_08375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCX77_08380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_08395	COG1982	Orn Lys Arg decarboxylase major
KCX77_08400	COG4476	Belongs to the UPF0223 family
KCX77_08405	COG4493	Belongs to the UPF0637 family
KCX77_08415	COG0483	inositol monophosphate 1-phosphatase activity
KCX77_08425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KCX77_08455	COG1217	gtp-binding protein TYPA
KCX77_08465	COG4896	Protein conserved in bacteria
KCX77_08475	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCX77_08480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCX77_08485	COG2066	Belongs to the glutaminase family
KCX77_08490	COG4838	Belongs to the UPF0358 family
KCX77_08495	COG0772	Belongs to the SEDS family
KCX77_08500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KCX77_08505	COG1612	heme a metabolic process
KCX77_08515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCX77_08515	COG2010	Cytochrome c
KCX77_08520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCX77_08525	COG1845	cytochrome c oxidase, subunit III
KCX77_08530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCX77_08535	COG3336	cytochrome c oxidase
KCX77_08545	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KCX77_08550	COG2340	Cysteine-rich secretory protein family
KCX77_08570	COG3679	Belongs to the UPF0342 family
KCX77_08575	COG4471	UPF0298 protein
KCX77_08585	COG0742	ribosomal rna small subunit methyltransferase
KCX77_08590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCX77_08595	COG3314	Sporulation integral membrane protein YlbJ
KCX77_08600	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCX77_08605	COG3480	Lon protease (S16) C-terminal proteolytic domain
KCX77_08610	COG1323	Belongs to the UPF0348 family
KCX77_08615	COG1399	metal-binding, possibly nucleic acid-binding protein
KCX77_08635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCX77_08640	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KCX77_08645	COG2001	Belongs to the MraZ family
KCX77_08650	COG0275	rRNA processing
KCX77_08655	COG4839	cell division protein FtsL
KCX77_08660	COG0768	penicillin binding
KCX77_08665	COG0768	penicillin binding
KCX77_08670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCX77_08675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCX77_08680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCX77_08685	COG0772	Belongs to the SEDS family
KCX77_08690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCX77_08695	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCX77_08700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCX77_08705	COG3879	Bacterial protein of unknown function (DUF881)
KCX77_08710	COG3879	Bacterial protein of unknown function (DUF881)
KCX77_08715	COG3856	small basic protein
KCX77_08720	COG0849	cell division
KCX77_08725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCX77_08730	COG1404	Belongs to the peptidase S8 family
KCX77_08730	COG4412	M6 family metalloprotease domain protein
KCX77_08740	COG1191	sigma factor activity
KCX77_08745	COG1191	sigma factor activity
KCX77_08750	COG1119	ATPase activity
KCX77_08755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCX77_08760	COG1873	PFAM PRC-barrel domain
KCX77_08765	COG1496	oxidoreductase activity
KCX77_08770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCX77_08775	COG1799	cell septum assembly
KCX77_08780	COG0762	integral membrane protein
KCX77_08785	COG2302	S4 RNA-binding domain
KCX77_08790	COG3599	regulation of cell shape
KCX77_08795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCX77_08800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCX77_08805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCX77_08810	COG0564	pseudouridine synthase activity
KCX77_08820	COG2233	PERMEase
KCX77_08825	COG0540	Belongs to the ATCase OTCase family
KCX77_08830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCX77_08835	COG0505	Belongs to the CarA family
KCX77_08840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCX77_08845	COG0543	2 iron, 2 sulfur cluster binding
KCX77_08850	COG0167	dihydroorotate dehydrogenase activity
KCX77_08855	COG0284	orotidine-5'-phosphate decarboxylase activity
KCX77_08860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCX77_08865	COG0175	sulfate reduction
KCX77_08870	COG0306	phosphate transporter
KCX77_08875	COG2046	Belongs to the sulfate adenylyltransferase family
KCX77_08880	COG0529	Catalyzes the synthesis of activated sulfate
KCX77_08885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCX77_08890	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KCX77_08895	COG1648	precorrin-2 dehydrogenase activity
KCX77_08900	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KCX77_08905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KCX77_08910	COG1561	YicC-like family, N-terminal region
KCX77_08920	COG0194	GDP metabolic process
KCX77_08925	COG1758	RNA polymerase activity
KCX77_08930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCX77_08935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCX77_08940	COG0242	peptide deformylase activity
KCX77_08945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCX77_08950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCX77_08950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCX77_08960	COG0631	protein serine/threonine phosphatase activity
KCX77_08965	COG0515	serine threonine protein kinase
KCX77_08965	COG2815	serine threonine protein kinase
KCX77_08970	COG1162	GTPase activity
KCX77_08975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KCX77_08980	COG1564	THIamine pyrophosphokinase
KCX77_08990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KCX77_08995	COG1302	Protein conserved in bacteria
KCX77_09000	COG1461	Dihydroxyacetone kinase
KCX77_09005	COG1760	l-serine dehydratase
KCX77_09010	COG1760	l-serine dehydratase
KCX77_09015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCX77_09020	COG1349	DNA-binding transcription factor activity
KCX77_09020	COG2050	protein possibly involved in aromatic compounds catabolism
KCX77_09030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCX77_09035	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_09045	COG0571	ribonuclease III activity
KCX77_09050	COG1196	nuclear chromosome segregation
KCX77_09055	COG0552	protein localization to endoplasmic reticulum
KCX77_09060	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCX77_09065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCX77_09070	COG0228	four-way junction DNA binding
KCX77_09075	COG1837	Belongs to the UPF0109 family
KCX77_09085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCX77_09100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCX77_09105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCX77_09115	COG2257	FlhB HrpN YscU SpaS Family
KCX77_09125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KCX77_09130	COG0758	DNA mediated transformation
KCX77_09135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCX77_09140	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCX77_09145	COG4974	Belongs to the 'phage' integrase family
KCX77_09150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KCX77_09155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCX77_09165	COG1815	bacterial-type flagellum-dependent cell motility
KCX77_09170	COG1558	bacterial-type flagellum-dependent cell motility
KCX77_09175	COG1677	Flagellar hook-basal body complex protein FliE
KCX77_09180	COG1766	The M ring may be actively involved in energy transduction
KCX77_09185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCX77_09190	COG1317	bacterial-type flagellum organization
KCX77_09195	COG1157	protein secretion by the type III secretion system
KCX77_09200	COG2882	bacterial-type flagellum organization
KCX77_09205	COG3334	PFAM MgtE intracellular
KCX77_09210	COG3144	bacterial-type flagellum assembly
KCX77_09215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KCX77_09220	COG4786	Flagellar basal body rod
KCX77_09225	COG1582	Flagellar protein (FlbD)
KCX77_09230	COG1580	Controls the rotational direction of flagella during chemotaxis
KCX77_09235	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCX77_09240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCX77_09240	COG1776	CheC inhibitor of MCP methylation
KCX77_09245	COG2201	protein-glutamate methylesterase activity
KCX77_09250	COG3190	flagellar
KCX77_09255	COG1338	Plays a role in the flagellum-specific transport system
KCX77_09260	COG1987	bacterial-type flagellum assembly
KCX77_09265	COG1684	flagellar biosynthetic protein fliR
KCX77_09270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCX77_09275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCX77_09280	COG1419	protein localization to endoplasmic reticulum
KCX77_09285	COG0455	bacterial-type flagellum organization
KCX77_09290	COG2201	protein-glutamate methylesterase activity
KCX77_09295	COG0643	Histidine kinase
KCX77_09295	COG2198	Histidine kinase
KCX77_09300	COG0835	chemotaxis
KCX77_09305	COG1776	CheC inhibitor of MCP methylation
KCX77_09310	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KCX77_09315	COG1191	sigma factor activity
KCX77_09330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCX77_09335	COG0528	UMP kinase activity
KCX77_09340	COG0233	cytoplasmic translational termination
KCX77_09345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCX77_09350	COG4589	Belongs to the CDS family
KCX77_09355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCX77_09360	COG0750	zinc metalloprotease
KCX77_09365	COG0442	prolyl-tRNA aminoacylation
KCX77_09370	COG2176	DNA-directed DNA polymerase activity
KCX77_09375	COG0779	Required for maturation of 30S ribosomal subunits
KCX77_09380	COG0195	Participates in both transcription termination and antitermination
KCX77_09385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KCX77_09390	COG1358	cellular component organization or biogenesis
KCX77_09395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCX77_09400	COG1550	Protein conserved in bacteria
KCX77_09405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCX77_09410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCX77_09415	COG0196	riboflavin kinase activity
KCX77_09425	COG1185	polyribonucleotide nucleotidyltransferase activity
KCX77_09430	COG0726	polysaccharide deacetylase
KCX77_09435	COG0612	Peptidase, M16
KCX77_09440	COG1873	PFAM PRC-barrel domain
KCX77_09445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCX77_09450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCX77_09455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCX77_09460	COG0527	aspartate kinase activity
KCX77_09470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCX77_09475	COG0740	serine-type endopeptidase activity
KCX77_09485	COG1674	ftsk spoiiie
KCX77_09485	COG4980	gas vesicle protein
KCX77_09490	COG2188	Transcriptional regulator
KCX77_09495	COG2814	Major facilitator Superfamily
KCX77_09500	COG0612	Peptidase, M16
KCX77_09505	COG0612	Peptidase, M16
KCX77_09510	COG0300	oxidoreductase activity
KCX77_09525	COG1426	Protein conserved in bacteria
KCX77_09530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCX77_09535	COG1058	Belongs to the CinA family
KCX77_09535	COG1546	Belongs to the CinA family
KCX77_09540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCX77_09545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCX77_09555	COG1692	metallophosphoesterase
KCX77_09560	COG2359	stage V sporulation protein S
KCX77_09565	COG1063	alcohol dehydrogenase
KCX77_09570	COG0156	8-amino-7-oxononanoate synthase activity
KCX77_09585	COG4550	Control of competence regulator ComK, YlbF/YmcA
KCX77_09595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCX77_09600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCX77_09620	COG3226	Transcriptional regulator
KCX77_09625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_09630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCX77_09635	COG3321	synthase
KCX77_09640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCX77_09640	COG2070	2-Nitropropane dioxygenase
KCX77_09645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCX77_09650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCX77_09655	COG3425	synthase
KCX77_09660	COG1024	Enoyl-CoA hydratase
KCX77_09665	COG1024	Enoyl-CoA hydratase
KCX77_09670	COG0300	oxidoreductase activity
KCX77_09670	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_09670	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_09670	COG3321	synthase
KCX77_09675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCX77_09675	COG4221	oxidoreductase activity
KCX77_09675	COG0300	oxidoreductase activity
KCX77_09675	COG3321	synthase
KCX77_09680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_09680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCX77_09680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_09680	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_09680	COG3321	synthase
KCX77_09685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_09685	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_09685	COG3321	synthase
KCX77_09685	COG4221	oxidoreductase activity
KCX77_09690	COG3321	synthase
KCX77_09690	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KCX77_09690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCX77_09690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KCX77_09695	COG2124	cytochrome p450
KCX77_09705	COG1404	Belongs to the peptidase S8 family
KCX77_09710	COG4195	phage-related replication protein
KCX77_09715	COG1764	response to oxidative stress
KCX77_09725	COG2076	Multidrug Resistance protein
KCX77_09745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCX77_09770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCX77_09775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCX77_09780	COG4112	unkown
KCX77_09785	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_09790	COG0464	growth
KCX77_09795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCX77_09800	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KCX77_09805	COG0789	Transcriptional regulator
KCX77_09810	COG0174	glutamine synthetase
KCX77_09835	COG0456	acetyltransferase
KCX77_09860	COG4282	regulation of fungal-type cell wall biogenesis
KCX77_09865	COG5444	nuclease activity
KCX77_09875	COG4978	Transcriptional regulator
KCX77_09875	COG0789	Transcriptional regulator
KCX77_09905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCX77_09910	COG2273	Hydrolase Family 16
KCX77_09915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCX77_09940	COG3391	amine dehydrogenase activity
KCX77_09965	COG2223	nitrite transmembrane transporter activity
KCX77_09970	COG0395	ABC-type sugar transport system, permease component
KCX77_09975	COG1175	transmembrane transport
KCX77_09985	COG1609	Transcriptional regulator
KCX77_09990	COG1309	transcriptional regulator
KCX77_10000	COG0509	glycine decarboxylation via glycine cleavage system
KCX77_10010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_10020	COG3118	belongs to the thioredoxin family
KCX77_10025	COG0492	ferredoxin-NADP+ reductase activity
KCX77_10045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCX77_10050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_10065	COG0657	acetylesterase activity
KCX77_10070	COG1011	Hydrolase
KCX77_10085	COG2318	DinB family
KCX77_10090	COG0653	protein targeting
KCX77_10095	COG2367	Beta-lactamase
KCX77_10105	COG4641	Protein conserved in bacteria
KCX77_10105	COG1388	LysM domain
KCX77_10110	COG1388	LysM domain
KCX77_10115	COG3858	chitin binding
KCX77_10125	COG2720	vancomycin resistance protein
KCX77_10130	COG5553	Cysteine dioxygenase type I
KCX77_10145	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_10160	COG0456	acetyltransferase
KCX77_10165	COG4978	Transcriptional regulator
KCX77_10165	COG0789	Transcriptional regulator
KCX77_10170	COG2030	dehydratase
KCX77_10185	COG2135	peptidase activity
KCX77_10200	COG0457	Tetratricopeptide repeat
KCX77_10215	COG1131	(ABC) transporter
KCX77_10260	COG4195	phage-related replication protein
KCX77_10265	COG3619	membrane
KCX77_10285	COG4195	phage-related replication protein
KCX77_10310	COG5577	PFAM Coat F domain
KCX77_10320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCX77_10325	COG1388	LysM domain
KCX77_10330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KCX77_10335	COG4224	UPF0291 protein
KCX77_10340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCX77_10350	COG3763	UPF0154 protein
KCX77_10360	COG0785	Cytochrome C biogenesis protein
KCX77_10365	COG2201	protein-glutamate methylesterase activity
KCX77_10370	COG4846	Membrane protein involved in cytochrome C biogenesis
KCX77_10380	COG0071	Belongs to the small heat shock protein (HSP20) family
KCX77_10395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCX77_10400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_10420	COG0824	Thioesterase
KCX77_10430	COG4841	protein insertion into membrane
KCX77_10435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KCX77_10440	COG1832	CoA-binding protein
KCX77_10445	COG0187	DNA topoisomerase II activity
KCX77_10450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCX77_10460	COG1115	amino acid carrier protein
KCX77_10485	COG5520	Belongs to the glycosyl hydrolase 30 family
KCX77_10500	COG0586	Pfam SNARE associated Golgi protein
KCX77_10505	COG2404	hydrolase activity, acting on ester bonds
KCX77_10510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCX77_10515	COG1024	Enoyl-CoA hydratase
KCX77_10520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCX77_10525	COG0511	ligase activity, forming carbon-carbon bonds
KCX77_10530	COG0439	Biotin carboxylase
KCX77_10535	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_10540	COG1960	acyl-CoA dehydrogenase activity
KCX77_10545	COG1649	PFAM Uncharacterised BCR, COG1649
KCX77_10555	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KCX77_10555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_10560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_10565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_10570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_10575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_10580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCX77_10580	COG1017	nitric oxide dioxygenase activity
KCX77_10585	COG2027	D-alanyl-D-alanine carboxypeptidase
KCX77_10590	COG2017	converts alpha-aldose to the beta-anomer
KCX77_10610	COG0582	viral genome integration into host DNA
KCX77_10615	COG0166	Belongs to the GPI family
KCX77_10620	COG0405	Gamma-glutamyltransferase
KCX77_10630	COG0604	alcohol dehydrogenase
KCX77_10635	COG0493	'glutamate synthase
KCX77_10640	COG0070	glutamate synthase
KCX77_10640	COG0067	glutamate synthase
KCX77_10640	COG0069	glutamate synthase activity
KCX77_10645	COG0583	DNA-binding transcription factor activity
KCX77_10650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCX77_10685	COG0693	protein deglycase activity
KCX77_10695	COG0300	oxidoreductase activity
KCX77_10700	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KCX77_10705	COG2318	DinB family
KCX77_10710	COG2814	Major facilitator Superfamily
KCX77_10715	COG1070	Carbohydrate kinase
KCX77_10720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCX77_10725	COG0243	molybdopterin cofactor binding
KCX77_10740	COG1309	transcriptional regulator
KCX77_10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCX77_10750	COG0662	Cupin 2, conserved barrel domain protein
KCX77_10750	COG2207	Transcriptional regulator
KCX77_10755	COG1309	transcriptional regulator
KCX77_10760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_10765	COG3708	Transcriptional regulator
KCX77_10770	COG2378	regulation of single-species biofilm formation
KCX77_10780	COG0640	Transcriptional regulator
KCX77_10785	COG0741	lytic transglycosylase activity
KCX77_10790	COG2322	membrane
KCX77_10805	COG3239	Fatty acid desaturase
KCX77_10810	COG4585	Histidine kinase
KCX77_10815	COG2197	response regulator
KCX77_10825	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_10830	COG3584	3D domain protein
KCX77_10830	COG1388	LysM domain
KCX77_10835	COG0514	ATP-dependent DNA helicase (RecQ)
KCX77_10845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCX77_10850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCX77_10870	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_10875	COG1657	PFAM Prenyltransferase squalene oxidase
KCX77_10880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCX77_10885	COG0733	neurotransmitter:sodium symporter activity
KCX77_10890	COG0385	Bile acid
KCX77_10895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCX77_10900	COG0567	Dehydrogenase, E1 component
KCX77_10905	COG4548	von Willebrand factor, type A
KCX77_10910	COG0714	Associated with various cellular activities
KCX77_10915	COG2032	superoxide dismutase activity
KCX77_10920	COG0791	NLP P60 protein
KCX77_10920	COG1388	LysM domain
KCX77_10925	COG1819	glycosyl
KCX77_10930	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCX77_10935	COG0534	Mate efflux family protein
KCX77_10940	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_10945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCX77_10950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCX77_10960	COG2962	Rard protein
KCX77_10975	COG2610	gluconate transmembrane transporter activity
KCX77_10980	COG1942	4-Oxalocrotonate Tautomerase
KCX77_10985	COG1733	regulation of RNA biosynthetic process
KCX77_10990	COG0778	Nitroreductase
KCX77_10995	COG0400	carboxylic ester hydrolase activity
KCX77_11000	COG0346	lactoylglutathione lyase activity
KCX77_11010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_11015	COG0793	Belongs to the peptidase S41A family
KCX77_11015	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_11020	COG2226	methyltransferase
KCX77_11030	COG1876	peptidase activity
KCX77_11035	COG0813	purine-nucleoside phosphorylase activity
KCX77_11050	COG0671	phosphoesterase, PA-phosphatase related
KCX77_11080	COG1509	lysine 2,3-aminomutase activity
KCX77_11085	COG0456	acetyltransferase
KCX77_11090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCX77_11095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KCX77_11100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCX77_11105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCX77_11115	COG0456	acetyltransferase
KCX77_11120	COG0463	Glycosyl transferase, family 2
KCX77_11135	COG4641	Protein conserved in bacteria
KCX77_11140	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KCX77_11145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCX77_11170	COG3397	chitin binding
KCX77_11180	COG3655	Transcriptional regulator
KCX77_11185	COG3739	integral membrane protein
KCX77_11195	COG2207	Transcriptional regulator
KCX77_11195	COG3708	Transcriptional regulator
KCX77_11200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCX77_11220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCX77_11225	COG1846	Transcriptional regulator
KCX77_11230	COG0534	Mate efflux family protein
KCX77_11240	COG4698	Protein conserved in bacteria
KCX77_11245	COG2755	lipolytic protein G-D-S-L family
KCX77_11250	COG1999	signal sequence binding
KCX77_11260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCX77_11265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KCX77_11270	COG1272	protein, Hemolysin III
KCX77_11275	COG0204	Acyl-transferase
KCX77_11280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCX77_11290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KCX77_11300	COG2136	Putative SAM-dependent methyltransferase
KCX77_11300	COG2521	methyltransferase
KCX77_11315	COG1413	lyase activity
KCX77_11320	COG1418	mRNA catabolic process
KCX77_11325	COG0386	Belongs to the glutathione peroxidase family
KCX77_11330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KCX77_11335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCX77_11340	COG1278	Cold shock
KCX77_11360	COG0328	RNA-DNA hybrid ribonuclease activity
KCX77_11365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCX77_11370	COG0328	RNA-DNA hybrid ribonuclease activity
KCX77_11380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCX77_11395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCX77_11405	COG1755	Isoprenylcysteine carboxyl methyltransferase
KCX77_11410	COG3424	synthase
KCX77_11415	COG2233	PERMEase
KCX77_11420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCX77_11425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KCX77_11435	COG0800	Aldolase
KCX77_11440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCX77_11445	COG1609	Transcriptional regulator
KCX77_11450	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KCX77_11455	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_11460	COG1199	ATP-dependent helicase activity
KCX77_11475	COG0116	Belongs to the methyltransferase superfamily
KCX77_11505	COG3359	exonuclease
KCX77_11510	COG1111	helicase
KCX77_11510	COG1205	dead DEAH box helicase
KCX77_11515	COG2190	(PTS) system
KCX77_11520	COG0071	Belongs to the small heat shock protein (HSP20) family
KCX77_11555	COG3331	DNA recombination
KCX77_11560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCX77_11560	COG4499	WXG100 protein secretion system (Wss), protein YukC
KCX77_11570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCX77_11575	COG3935	DnaD domain protein
KCX77_11580	COG0017	Asparaginyl-tRNA synthetase
KCX77_11585	COG0436	Aminotransferase
KCX77_11590	COG5353	protein conserved in bacteria
KCX77_11600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCX77_11600	COG1199	ATP-dependent helicase activity
KCX77_11605	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KCX77_11610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KCX77_11615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCX77_11620	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCX77_11620	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCX77_11625	COG0617	tRNA 3'-terminal CCA addition
KCX77_11630	COG0438	transferase activity, transferring glycosyl groups
KCX77_11635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCX77_11650	COG1694	Mazg nucleotide pyrophosphohydrolase
KCX77_11655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_11660	COG2140	Oxalate decarboxylase
KCX77_11670	COG4347	Protein of unknown function (DUF1405)
KCX77_11675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCX77_11675	COG2010	Cytochrome c
KCX77_11680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCX77_11685	COG0723	plastoquinol--plastocyanin reductase activity
KCX77_11695	COG5582	Belongs to the UPF0302 family
KCX77_11700	COG0457	Tetratricopeptide repeat
KCX77_11705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KCX77_11710	COG0287	Prephenate dehydrogenase
KCX77_11715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCX77_11720	COG0159	tryptophan synthase activity
KCX77_11740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCX77_11745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCX77_11750	COG4401	Chorismate mutase type I
KCX77_11755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCX77_11765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KCX77_11770	COG0105	UTP biosynthetic process
KCX77_11775	COG0142	geranyltranstransferase activity
KCX77_11785	COG0142	geranyltranstransferase activity
KCX77_11795	COG0302	gtp cyclohydrolase
KCX77_11800	COG0776	regulation of translation
KCX77_11805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCX77_11820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCX77_11825	COG1160	GTP binding
KCX77_11850	COG1304	FMN binding
KCX77_11855	COG0539	negative regulation of cytoplasmic translation
KCX77_11860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCX77_11870	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KCX77_11875	COG2959	enzyme of heme biosynthesis
KCX77_11880	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_11880	COG3773	Cell wall hydrolase
KCX77_11885	COG2339	peptidase activity
KCX77_11890	COG0492	ferredoxin-NADP+ reductase activity
KCX77_11895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCX77_11900	COG4862	establishment of competence for transformation
KCX77_11905	COG1408	metallophosphoesterase
KCX77_11915	COG1388	LysM domain
KCX77_11920	COG1266	CAAX protease self-immunity
KCX77_11925	COG0514	ATP-dependent DNA helicase (RecQ)
KCX77_11930	COG4955	Helix-turn-helix domain
KCX77_11935	COG1141	Ferredoxin
KCX77_11940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCX77_11945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCX77_11950	COG0710	3-dehydroquinate dehydratase activity
KCX77_11960	COG1595	DNA-templated transcription, initiation
KCX77_11965	COG5002	protein histidine kinase activity
KCX77_11970	COG0745	RESPONSE REGULATOR receiver
KCX77_11975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCX77_11980	COG1333	cytochrome c biogenesis protein
KCX77_11985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_11990	COG1187	pseudouridine synthase activity
KCX77_11995	COG0700	Nucleoside recognition
KCX77_12000	COG2715	membrane protein required for spore maturation
KCX77_12005	COG1686	Belongs to the peptidase S11 family
KCX77_12015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCX77_12020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCX77_12030	COG1547	Domain of unknown function (DUF309)
KCX77_12035	COG0456	acetyltransferase
KCX77_12040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCX77_12045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCX77_12045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCX77_12050	COG0307	riboflavin synthase, alpha
KCX77_12055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCX77_12055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCX77_12065	COG0681	Belongs to the peptidase S26 family
KCX77_12070	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KCX77_12075	COG1278	Cold shock
KCX77_12080	COG0823	Involved in the tonB-independent uptake of proteins
KCX77_12090	COG3420	alginic acid biosynthetic process
KCX77_12100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCX77_12105	COG4086	secreted protein
KCX77_12110	COG0019	diaminopimelate decarboxylase activity
KCX77_12115	COG0697	spore germination
KCX77_12130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCX77_12150	COG1191	sigma factor activity
KCX77_12155	COG2172	sigma factor antagonist activity
KCX77_12160	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_12165	COG1686	Belongs to the peptidase S11 family
KCX77_12170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCX77_12175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCX77_12180	COG4974	Belongs to the 'phage' integrase family
KCX77_12190	COG0735	belongs to the Fur family
KCX77_12195	COG1300	Membrane
KCX77_12205	COG0281	malic enzyme
KCX77_12210	COG1757	Na H antiporter
KCX77_12215	COG1027	Aspartate ammonia-lyase
KCX77_12220	COG0252	asparaginase activity
KCX77_12225	COG1396	sequence-specific DNA binding
KCX77_12230	COG1379	DNA repair
KCX77_12235	COG0494	nUDIX hydrolase
KCX77_12245	COG0667	Aldo Keto reductase
KCX77_12255	COG1073	alpha beta
KCX77_12265	COG4918	Iron-sulphur cluster biosynthesis
KCX77_12270	COG0456	acetyltransferase
KCX77_12270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCX77_12275	COG2329	Antibiotic biosynthesis monooxygenase
KCX77_12280	COG0456	acetyltransferase
KCX77_12290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCX77_12300	COG0628	permease
KCX77_12320	COG0346	lactoylglutathione lyase activity
KCX77_12325	COG1072	(Pantothenic acid kinase))
KCX77_12330	COG3048	D-serine ammonia-lyase activity
KCX77_12340	COG0300	oxidoreductase activity
KCX77_12345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_12350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCX77_12355	COG4187	Peptidase family M20/M25/M40
KCX77_12360	COG1902	pentaerythritol trinitrate reductase activity
KCX77_12365	COG0596	Alpha beta hydrolase
KCX77_12375	COG1234	tRNA 3'-trailer cleavage
KCX77_12380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCX77_12385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCX77_12390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCX77_12400	COG0706	membrane insertase activity
KCX77_12405	COG3361	conserved protein (COG2071)
KCX77_12410	COG2195	Cleaves the N-terminal amino acid of tripeptides
KCX77_12415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCX77_12420	COG0346	lactoylglutathione lyase activity
KCX77_12430	COG1376	ErfK ybiS ycfS ynhG family protein
KCX77_12435	COG4129	membrane
KCX77_12440	COG1126	abc transporter atp-binding protein
KCX77_12445	COG0765	amino acid transport
KCX77_12450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCX77_12460	COG1597	lipid kinase activity
KCX77_12470	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCX77_12475	COG0022	dehydrogenase e1 component
KCX77_12480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCX77_12485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCX77_12490	COG3426	butyrate kinase activity
KCX77_12495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCX77_12500	COG0280	phosphate acetyltransferase
KCX77_12505	COG3290	protein histidine kinase activity
KCX77_12505	COG3829	transcription factor binding
KCX77_12515	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KCX77_12520	COG2079	MmgE PrpD family protein
KCX77_12525	COG0372	Belongs to the citrate synthase family
KCX77_12530	COG1960	acyl-CoA dehydrogenase activity
KCX77_12535	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCX77_12540	COG0183	Belongs to the thiolase family
KCX77_12545	COG0584	glycerophosphoryl diester phosphodiesterase
KCX77_12550	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_12560	COG1902	pentaerythritol trinitrate reductase activity
KCX77_12570	COG0745	RESPONSE REGULATOR receiver
KCX77_12575	COG0750	zinc metalloprotease
KCX77_12580	COG0497	DNA recombination
KCX77_12585	COG1438	arginine binding
KCX77_12590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KCX77_12595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCX77_12600	COG0142	geranyltranstransferase activity
KCX77_12605	COG1722	exodeoxyribonuclease VII activity
KCX77_12610	COG1570	exodeoxyribonuclease VII activity
KCX77_12615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCX77_12620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCX77_12625	COG1302	Protein conserved in bacteria
KCX77_12630	COG0439	Biotin carboxylase
KCX77_12635	COG0511	ligase activity, forming carbon-carbon bonds
KCX77_12675	COG3854	ATPases associated with a variety of cellular activities
KCX77_12685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCX77_12690	COG0006	proline dipeptidase activity
KCX77_12695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCX77_12705	COG3872	metal-dependent enzyme
KCX77_12715	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCX77_12720	COG1321	iron dependent repressor
KCX77_12725	COG0095	Lipoate-protein ligase
KCX77_12730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCX77_12735	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCX77_12740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCX77_12745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KCX77_12750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCX77_12765	COG1396	sequence-specific DNA binding
KCX77_12775	COG0681	Belongs to the peptidase S26 family
KCX77_12800	COG4940	Competence protein ComGF
KCX77_12810	COG4970	Tfp pilus assembly protein FimT
KCX77_12815	COG4537	Required for transformation and DNA binding
KCX77_12820	COG1459	type II secretion system
KCX77_12825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCX77_12830	COG0598	Magnesium transport protein CorA
KCX77_12835	COG1253	flavin adenine dinucleotide binding
KCX77_12840	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_12850	COG1393	Belongs to the ArsC family
KCX77_12860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_12870	COG0011	TIGRFAM Protein of
KCX77_12880	COG2866	Carboxypeptidase
KCX77_12885	COG1368	sulfuric ester hydrolase activity
KCX77_12890	COG1940	carbohydrate kinase activity
KCX77_12895	COG4483	Protein conserved in bacteria
KCX77_12900	COG0457	Tetratricopeptide repeat
KCX77_12900	COG0705	Rhomboid family
KCX77_12910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCX77_12920	COG0438	transferase activity, transferring glycosyl groups
KCX77_12935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCX77_12940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCX77_12945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCX77_12950	COG0581	inorganic phosphate transmembrane transporter activity
KCX77_12955	COG0573	inorganic phosphate transmembrane transporter activity
KCX77_12960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCX77_12965	COG0768	penicillin binding
KCX77_12970	COG0477	Major facilitator Superfamily
KCX77_12975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCX77_12980	COG2839	Protein conserved in bacteria
KCX77_12985	COG5521	maltodextrose utilization protein MalA
KCX77_12990	COG1388	LysM domain
KCX77_13000	COG4709	membrane
KCX77_13005	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KCX77_13010	COG0735	belongs to the Fur family
KCX77_13015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_13025	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KCX77_13030	COG0513	Belongs to the DEAD box helicase family
KCX77_13040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCX77_13045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCX77_13050	COG2384	SAM-dependent methyltransferase
KCX77_13055	COG2010	Cytochrome c
KCX77_13060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCX77_13065	COG0358	DNA primase activity
KCX77_13070	COG1671	Belongs to the UPF0178 family
KCX77_13075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCX77_13080	COG0517	IMP dehydrogenase activity
KCX77_13085	COG0751	glycine-tRNA ligase activity
KCX77_13090	COG0752	glycyl-tRNA synthetase alpha subunit
KCX77_13095	COG1381	Involved in DNA repair and RecF pathway recombination
KCX77_13105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCX77_13110	COG0295	cytidine deaminase activity
KCX77_13115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCX77_13125	COG1480	7TM receptor with intracellular HD hydrolase
KCX77_13130	COG1702	phosphate starvation-inducible protein PhoH
KCX77_13135	COG0561	phosphatase activity
KCX77_13150	COG4864	UPF0365 protein
KCX77_13155	COG1030	water channel activity
KCX77_13160	COG1610	YqeY-like protein
KCX77_13170	COG1283	sodium-dependent phosphate transmembrane transporter activity
KCX77_13175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCX77_13180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCX77_13200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCX77_13205	COG1420	regulation of RNA biosynthetic process
KCX77_13210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCX77_13215	COG0481	GTPase activity
KCX77_13225	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_13240	COG1466	dna polymerase III delta subunit
KCX77_13255	COG2333	competence protein COMEC
KCX77_13255	COG0658	competence protein
KCX77_13260	COG2131	deaminase
KCX77_13265	COG1596	polysaccharide export
KCX77_13265	COG1555	photosystem II stabilization
KCX77_13270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCX77_13275	COG2226	methyltransferase
KCX77_13280	COG0799	negative regulation of ribosome biogenesis
KCX77_13285	COG1713	HD superfamily hydrolase involved in NAD metabolism
KCX77_13290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCX77_13295	COG1534	Rna-binding protein
KCX77_13300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCX77_13305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCX77_13310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KCX77_13320	COG2755	lipolytic protein G-D-S-L family
KCX77_13335	COG0398	Pfam SNARE associated Golgi protein
KCX77_13350	COG5444	nuclease activity
KCX77_13370	COG2732	(Barnase) inhibitor
KCX77_13395	COG1725	Transcriptional regulator
KCX77_13410	COG3443	Belongs to the bacterial solute-binding protein 9 family
KCX77_13425	COG0583	DNA-binding transcription factor activity
KCX77_13430	COG2814	Major facilitator Superfamily
KCX77_13435	COG2176	DNA-directed DNA polymerase activity
KCX77_13440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCX77_13440	COG2124	cytochrome p450
KCX77_13445	COG1309	transcriptional regulator
KCX77_13450	COG2226	methyltransferase
KCX77_13465	COG2116	formate transmembrane transporter activity
KCX77_13470	COG5609	conserved protein (DUF2294)
KCX77_13475	COG3383	formate dehydrogenase (NAD+) activity
KCX77_13480	COG2427	Protein of unknown function (DUF1641)
KCX77_13490	COG0626	cystathionine gamma-synthase activity
KCX77_13495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCX77_13500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCX77_13505	COG2226	methyltransferase
KCX77_13520	COG0768	penicillin binding
KCX77_13525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCX77_13530	COG0572	uridine kinase
KCX77_13535	COG0826	peptidase U32
KCX77_13540	COG0826	peptidase U32
KCX77_13545	COG4122	O-methyltransferase activity
KCX77_13550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCX77_13555	COG3906	Belongs to the UPF0473 family
KCX77_13560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCX77_13565	COG4472	Bacterial protein of unknown function (DUF965)
KCX77_13570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCX77_13575	COG0628	permease
KCX77_13580	COG1126	abc transporter atp-binding protein
KCX77_13585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCX77_13590	COG0765	amino acid transport
KCX77_13595	COG0765	amino acid transport
KCX77_13610	COG3881	PFAM PRC-barrel domain
KCX77_13615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCX77_13620	COG0457	Tetratricopeptide repeat
KCX77_13630	COG1104	cysteine desulfurase activity
KCX77_13635	COG1959	2 iron, 2 sulfur cluster binding
KCX77_13640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCX77_13645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCX77_13655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KCX77_13670	COG3103	Sh3 type 3 domain protein
KCX77_13670	COG4991	sh3 domain protein
KCX77_13670	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_13675	COG1490	D-aminoacyl-tRNA deacylase activity
KCX77_13680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCX77_13690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KCX77_13690	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KCX77_13695	COG5416	Lipopolysaccharide assembly protein A domain
KCX77_13700	COG0490	domain, Protein
KCX77_13705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCX77_13705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCX77_13715	COG2244	polysaccharide biosynthetic process
KCX77_13720	COG2323	membrane
KCX77_13730	COG1862	Preprotein translocase
KCX77_13740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCX77_13750	COG2255	four-way junction helicase activity
KCX77_13755	COG0632	four-way junction helicase activity
KCX77_13765	COG2814	Major facilitator Superfamily
KCX77_13770	COG2112	serine threonine protein kinase
KCX77_13780	COG0217	transcriptional regulatory protein
KCX77_13800	COG3394	polysaccharide catabolic process
KCX77_13805	COG2188	Transcriptional regulator
KCX77_13810	COG1486	melibiose metabolic process
KCX77_13815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCX77_13820	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCX77_13825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCX77_13840	COG1388	LysM domain
KCX77_13845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KCX77_13850	COG0157	Belongs to the NadC ModD family
KCX77_13855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KCX77_13860	COG1104	cysteine desulfurase activity
KCX77_13865	COG1827	regulation of RNA biosynthetic process
KCX77_13870	COG0077	Prephenate dehydratase
KCX77_13875	COG4492	Belongs to the UPF0735 family
KCX77_13880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCX77_13885	COG3290	protein histidine kinase activity
KCX77_13890	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCX77_13895	COG2868	ribosomal protein
KCX77_13900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCX77_13905	COG1994	Peptidase M50
KCX77_13910	COG0739	heme binding
KCX77_13915	COG2894	cell division
KCX77_13920	COG0850	regulation of cytokinetic process
KCX77_13925	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KCX77_13935	COG1077	Cell shape determining protein MreB Mrl
KCX77_13940	COG2003	Belongs to the UPF0758 family
KCX77_13945	COG0424	maF-like protein
KCX77_13955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KCX77_13960	COG0285	dihydrofolate synthase activity
KCX77_13965	COG0525	valine-tRNA ligase activity
KCX77_13975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCX77_13980	COG1388	LysM domain
KCX77_13980	COG1388	LysM domain
KCX77_13985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCX77_13990	COG0113	porphobilinogen synthase activity
KCX77_13995	COG1587	Uroporphyrinogen-III synthase
KCX77_14005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KCX77_14010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCX77_14020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KCX77_14025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KCX77_14030	COG0470	DNA polymerase III
KCX77_14030	COG1067	ATP-dependent peptidase activity
KCX77_14040	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCX77_14045	COG0457	Tetratricopeptide repeat
KCX77_14045	COG1477	protein flavinylation
KCX77_14050	COG0066	3-isopropylmalate dehydratase activity
KCX77_14055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCX77_14060	COG0473	3-isopropylmalate dehydrogenase activity
KCX77_14065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCX77_14070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCX77_14075	COG0440	acetolactate synthase activity
KCX77_14080	COG0028	Belongs to the TPP enzyme family
KCX77_14085	COG0454	-acetyltransferase
KCX77_14095	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KCX77_14105	COG0622	Phosphoesterase
KCX77_14110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCX77_14115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCX77_14120	COG5401	PFAM Sporulation and spore germination
KCX77_14125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KCX77_14130	COG1846	Transcriptional regulator
KCX77_14135	COG2197	response regulator
KCX77_14140	COG0824	Thioesterase
KCX77_14145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCX77_14150	COG1053	succinate dehydrogenase
KCX77_14155	COG2009	succinate dehydrogenase
KCX77_14160	COG1719	4-vinyl reductase, 4VR
KCX77_14165	COG0527	aspartate kinase activity
KCX77_14170	COG0322	excinuclease ABC activity
KCX77_14175	COG3118	belongs to the thioredoxin family
KCX77_14180	COG3534	alpha-L-arabinofuranosidase
KCX77_14185	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KCX77_14190	COG2086	electron transfer activity
KCX77_14195	COG1024	Enoyl-CoA hydratase
KCX77_14200	COG1309	transcriptional regulator
KCX77_14205	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_14210	COG3766	membrane
KCX77_14215	COG1193	negative regulation of DNA recombination
KCX77_14220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCX77_14220	COG1796	DNA polymerase
KCX77_14225	COG1286	toxin biosynthetic process
KCX77_14230	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCX77_14240	COG0072	phenylalanine-tRNA ligase activity
KCX77_14240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCX77_14245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCX77_14250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCX77_14260	COG3835	regulator
KCX77_14265	COG0277	FAD linked oxidase domain protein
KCX77_14270	COG0247	lactate metabolic process
KCX77_14275	COG0346	lactoylglutathione lyase activity
KCX77_14280	COG1966	Carbon starvation protein
KCX77_14285	COG3534	alpha-L-arabinofuranosidase
KCX77_14290	COG0395	ABC-type sugar transport system, permease component
KCX77_14295	COG1175	transmembrane transport
KCX77_14300	COG1653	transport
KCX77_14305	COG0371	Dehydrogenase
KCX77_14310	COG0647	UMP catabolic process
KCX77_14315	COG0235	Class ii aldolase
KCX77_14320	COG1069	ribulokinase activity
KCX77_14325	COG2160	L-arabinose isomerase activity
KCX77_14350	COG3507	Belongs to the glycosyl hydrolase 43 family
KCX77_14355	COG1363	Peptidase, m42
KCX77_14365	COG3326	Membrane
KCX77_14370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCX77_14375	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KCX77_14380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCX77_14400	COG1346	cytolysis
KCX77_14410	COG3279	Response regulator of the LytR AlgR family
KCX77_14415	COG3275	phosphorelay sensor kinase activity
KCX77_14420	COG1011	Hydrolase
KCX77_14425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCX77_14435	COG0398	Pfam SNARE associated Golgi protein
KCX77_14440	COG1484	DNA-dependent DNA replication
KCX77_14445	COG3611	Membrane attachment protein
KCX77_14450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCX77_14455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCX77_14460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCX77_14465	COG1733	regulation of RNA biosynthetic process
KCX77_14470	COG2814	Major facilitator Superfamily
KCX77_14475	COG0656	L-ascorbic acid biosynthetic process
KCX77_14480	COG0237	dephospho-CoA kinase activity
KCX77_14485	COG1971	Probably functions as a manganese efflux pump
KCX77_14490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCX77_14495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCX77_14495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCX77_14500	COG5002	protein histidine kinase activity
KCX77_14505	COG0745	RESPONSE REGULATOR receiver
KCX77_14515	COG0538	isocitrate dehydrogenase activity
KCX77_14520	COG0372	Belongs to the citrate synthase family
KCX77_14525	COG2707	UPF0756 membrane protein
KCX77_14530	COG0628	permease
KCX77_14535	COG3030	protein affecting phage T7 exclusion by the F plasmid
KCX77_14540	COG0469	pyruvate kinase activity
KCX77_14550	COG0825	malonyl-CoA metabolic process
KCX77_14555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCX77_14560	COG0281	malic enzyme
KCX77_14565	COG0587	DNA-directed DNA polymerase activity
KCX77_14585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KCX77_14595	COG4109	DRTGG domain
KCX77_14600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCX77_14605	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_14610	COG0165	Argininosuccinate lyase
KCX77_14615	COG0137	argininosuccinate synthase activity
KCX77_14620	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCX77_14630	COG0827	DNA restriction-modification system
KCX77_14635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCX77_14640	COG3874	Sporulation protein YtfJ
KCX77_14650	COG1714	RDD family
KCX77_14655	COG0616	signal peptide processing
KCX77_14660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCX77_14665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KCX77_14670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCX77_14680	COG0301	tRNA thio-modification
KCX77_14685	COG1104	cysteine desulfurase activity
KCX77_14690	COG1114	Component of the transport system for branched-chain amino acids
KCX77_14695	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCX77_14700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KCX77_14705	COG1309	transcriptional regulator
KCX77_14710	COG1956	GAF domain-containing protein
KCX77_14715	COG2203	Gaf domain
KCX77_14715	COG2199	diguanylate cyclase activity
KCX77_14725	COG2267	carboxylic ester hydrolase activity
KCX77_14745	COG1335	isochorismatase
KCX77_14765	COG2259	Doxx family
KCX77_14770	COG0346	lactoylglutathione lyase activity
KCX77_14780	COG0400	carboxylic ester hydrolase activity
KCX77_14785	COG0697	spore germination
KCX77_14790	COG0583	DNA-binding transcription factor activity
KCX77_14795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCX77_14800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KCX77_14805	COG0454	-acetyltransferase
KCX77_14810	COG0517	IMP dehydrogenase activity
KCX77_14815	COG0123	including yeast histone deacetylase and acetoin utilization protein
KCX77_14820	COG1360	Flagellar Motor Protein
KCX77_14825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCX77_14830	COG1609	Transcriptional regulator
KCX77_14835	COG1605	Chorismate mutase
KCX77_14835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KCX77_14840	COG3118	belongs to the thioredoxin family
KCX77_14845	COG4980	gas vesicle protein
KCX77_14850	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KCX77_14860	COG1674	ftsk spoiiie
KCX77_14865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCX77_14870	COG4848	Belongs to the UPF0354 family
KCX77_14875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_14885	COG1363	Peptidase, m42
KCX77_14890	COG5584	Small secreted protein
KCX77_14895	COG0281	malic enzyme
KCX77_14900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCX77_14905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KCX77_14915	COG0510	thiamine kinase activity
KCX77_14920	COG1523	belongs to the glycosyl hydrolase 13 family
KCX77_14925	COG1597	lipid kinase activity
KCX77_14935	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KCX77_14940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KCX77_14945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCX77_14950	COG2252	PERMEase
KCX77_14955	COG1349	DNA-binding transcription factor activity
KCX77_14960	COG1187	pseudouridine synthase activity
KCX77_14965	COG2244	polysaccharide biosynthetic process
KCX77_14970	COG2081	HI0933 family
KCX77_14975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KCX77_14985	COG5578	integral membrane protein
KCX77_14990	COG0673	inositol 2-dehydrogenase activity
KCX77_14995	COG1653	transport
KCX77_15000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KCX77_15005	COG4209	transmembrane transport
KCX77_15010	COG2207	Transcriptional regulator
KCX77_15015	COG1653	transport
KCX77_15020	COG0395	ABC-type sugar transport system, permease component
KCX77_15025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_15030	COG2124	cytochrome p450
KCX77_15035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCX77_15045	COG0156	8-amino-7-oxononanoate synthase activity
KCX77_15050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCX77_15055	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KCX77_15060	COG1073	alpha beta
KCX77_15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCX77_15070	COG0495	leucyl-tRNA aminoacylation
KCX77_15080	COG2202	Pas domain
KCX77_15080	COG1366	Belongs to the anti-sigma-factor antagonist family
KCX77_15085	COG2814	Major facilitator Superfamily
KCX77_15090	COG2433	Pfam Transposase IS66
KCX77_15095	COG0577	efflux transmembrane transporter activity
KCX77_15100	COG1136	(ABC) transporter
KCX77_15105	COG2205	protein histidine kinase activity
KCX77_15110	COG0745	RESPONSE REGULATOR receiver
KCX77_15115	COG0577	efflux transmembrane transporter activity
KCX77_15120	COG1136	(ABC) transporter
KCX77_15130	COG1131	(ABC) transporter
KCX77_15135	COG1725	Transcriptional regulator
KCX77_15150	COG1242	4 iron, 4 sulfur cluster binding
KCX77_15155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KCX77_15165	COG2267	carboxylic ester hydrolase activity
KCX77_15170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCX77_15175	COG1113	amino acid transport
KCX77_15180	COG0367	asparagine synthase
KCX77_15190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KCX77_15200	COG1506	peptidase
KCX77_15205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCX77_15210	COG1116	anion transmembrane transporter activity
KCX77_15215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KCX77_15220	COG0494	nUDIX hydrolase
KCX77_15230	COG4824	toxin secretion phage lysis holin
KCX77_15235	COG0783	Belongs to the Dps family
KCX77_15255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KCX77_15260	COG0288	reversible hydration of carbon dioxide
KCX77_15265	COG0523	cobalamin synthesis protein
KCX77_15275	COG1271	oxidase subunit
KCX77_15280	COG1294	oxidase, subunit
KCX77_15290	COG4305	rare lipoprotein A
KCX77_15300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCX77_15305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCX77_15305	COG1321	iron dependent repressor
KCX77_15310	COG1121	(ABC) transporter
KCX77_15315	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCX77_15320	COG4948	Mandelate Racemase Muconate Lactonizing
KCX77_15325	COG0318	PFAM AMP-dependent synthetase and ligase
KCX77_15330	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KCX77_15335	COG0596	Alpha beta hydrolase
KCX77_15340	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KCX77_15345	COG1169	isochorismate synthase
KCX77_15350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCX77_15355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCX77_15360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_15365	COG0438	transferase activity, transferring glycosyl groups
KCX77_15375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCX77_15380	COG0438	transferase activity, transferring glycosyl groups
KCX77_15385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCX77_15390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KCX77_15395	COG0058	SHG alpha-glucan phosphorylase activity
KCX77_15400	COG0297	glycogen (starch) synthase activity
KCX77_15405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCX77_15410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCX77_15415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCX77_15540	COG3859	Proton-coupled thiamine transporter YuaJ
KCX77_15545	COG3764	Sortase (surface protein transpeptidase)
KCX77_15555	COG2268	Band 7 protein
KCX77_15560	COG1585	Membrane protein implicated in regulation of membrane protease activity
KCX77_15565	COG2318	DinB family
KCX77_15575	COG1454	alcohol dehydrogenase
KCX77_15580	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_15585	COG1510	regulation of RNA biosynthetic process
KCX77_15595	COG0569	domain protein
KCX77_15600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KCX77_15605	COG4682	membrane
KCX77_15610	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCX77_15615	COG0477	Major facilitator Superfamily
KCX77_15625	COG5444	nuclease activity
KCX77_15650	COG0628	permease
KCX77_15655	COG0673	inositol 2-dehydrogenase activity
KCX77_15660	COG0693	protein deglycase activity
KCX77_15665	COG4806	L-rhamnose isomerase
KCX77_15670	COG3254	rhamnose metabolic process
KCX77_15675	COG1070	Carbohydrate kinase
KCX77_15680	COG1349	DNA-binding transcription factor activity
KCX77_15685	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_15685	COG3347	Dehydrogenase
KCX77_15690	COG0840	transmembrane signaling receptor activity
KCX77_15695	COG0840	transmembrane signaling receptor activity
KCX77_15700	COG0840	transmembrane signaling receptor activity
KCX77_15705	COG0840	transmembrane signaling receptor activity
KCX77_15720	COG2070	2-Nitropropane dioxygenase
KCX77_15725	COG0432	Pfam Uncharacterised protein family UPF0047
KCX77_15730	COG0366	Alpha amylase catalytic
KCX77_15735	COG1253	flavin adenine dinucleotide binding
KCX77_15740	COG2738	Putative neutral zinc metallopeptidase
KCX77_15755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCX77_15770	COG0166	Belongs to the GPI family
KCX77_15775	COG1979	alcohol dehydrogenase
KCX77_15780	COG1979	alcohol dehydrogenase
KCX77_15785	COG2155	Conserved Protein
KCX77_15790	COG1098	S1 RNA binding domain
KCX77_15795	COG0436	Aminotransferase
KCX77_15800	COG1522	sequence-specific DNA binding
KCX77_15805	COG2267	carboxylic ester hydrolase activity
KCX77_15815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KCX77_15820	COG2205	protein histidine kinase activity
KCX77_15830	COG5018	Exonuclease
KCX77_15835	COG2814	Major facilitator Superfamily
KCX77_15840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCX77_15845	COG3011	Protein conserved in bacteria
KCX77_15855	COG3290	protein histidine kinase activity
KCX77_15860	COG4565	transcriptional regulatory protein
KCX77_15865	COG1744	ABC transporter substrate-binding protein PnrA-like
KCX77_15870	COG3845	ABC transporter
KCX77_15875	COG4603	Belongs to the binding-protein-dependent transport system permease family
KCX77_15880	COG1079	Belongs to the binding-protein-dependent transport system permease family
KCX77_15885	COG3493	citrate carrier protein
KCX77_15895	COG2111	Na H antiporter
KCX77_15895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCX77_15900	COG2111	Na H antiporter
KCX77_15905	COG1006	Multisubunit Na H antiporter MnhC subunit
KCX77_15910	COG0651	ATP synthesis coupled electron transport
KCX77_15915	COG1863	multisubunit Na H antiporter MnhE subunit
KCX77_15920	COG2212	antiporter activity
KCX77_15925	COG1320	monovalent cation:proton antiporter activity
KCX77_15930	COG2050	protein possibly involved in aromatic compounds catabolism
KCX77_15935	COG2197	response regulator
KCX77_15940	COG4585	Histidine kinase
KCX77_15950	COG0142	geranyltranstransferase activity
KCX77_15965	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KCX77_15970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCX77_15975	COG1335	isochorismatase
KCX77_15980	COG5506	Protein of unknown function (DUF1694)
KCX77_15995	COG0628	permease
KCX77_16005	COG1418	mRNA catabolic process
KCX77_16010	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_16020	COG1511	domain protein
KCX77_16025	COG0433	COG0433 Predicted ATPase
KCX77_16025	COG1674	ftsk spoiiie
KCX77_16030	COG4499	WXG100 protein secretion system (Wss), protein YukC
KCX77_16035	COG5417	Belongs to the EsaB family
KCX77_16040	COG4842	Belongs to the WXG100 family
KCX77_16045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCX77_16045	COG2508	Transcriptional regulator
KCX77_16050	COG0686	Belongs to the AlaDH PNT family
KCX77_16055	COG5634	Uncharacterized conserved protein (DUF2278)
KCX77_16060	COG3251	PFAM MbtH domain protein
KCX77_16065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_16070	COG1535	isochorismatase
KCX77_16070	COG3433	isochorismatase activity
KCX77_16075	COG1021	2,3-dihydroxybenzoate-AMP ligase
KCX77_16080	COG1169	isochorismate synthase
KCX77_16085	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_16090	COG2819	hydrolase of the alpha beta superfamily
KCX77_16105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCX77_16110	COG1268	BioY protein
KCX77_16115	COG2056	Na+-H+ antiporter family
KCX77_16120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCX77_16125	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KCX77_16130	COG3584	3D domain protein
KCX77_16145	COG1252	NADH dehydrogenase
KCX77_16160	COG0516	GMP reductase activity
KCX77_16165	COG0316	Belongs to the HesB IscA family
KCX77_16170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCX77_16175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCX77_16180	COG4844	belongs to the
KCX77_16185	COG1252	NADH dehydrogenase
KCX77_16190	COG3479	Phenolic acid decarboxylase
KCX77_16195	COG4837	Protein of unknown function (DUF1462)
KCX77_16200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCX77_16205	COG0823	Involved in the tonB-independent uptake of proteins
KCX77_16205	COG1506	peptidase
KCX77_16205	COG4946	Tricorn protease homolog
KCX77_16210	COG0083	homoserine kinase activity
KCX77_16215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCX77_16220	COG0460	homoserine dehydrogenase
KCX77_16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCX77_16230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KCX77_16235	COG0647	UMP catabolic process
KCX77_16240	COG2445	Protein of unknown function DUF86
KCX77_16245	COG4470	Protein conserved in bacteria
KCX77_16260	COG0739	heme binding
KCX77_16270	COG3377	Domain of unknown function (DUF1805)
KCX77_16275	COG0737	Belongs to the 5'-nucleotidase family
KCX77_16280	COG0730	response to heat
KCX77_16285	COG1801	Protein of unknown function DUF72
KCX77_16300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCX77_16305	COG2508	Transcriptional regulator
KCX77_16315	COG1595	DNA-templated transcription, initiation
KCX77_16395	COG1131	(ABC) transporter
KCX77_16415	COG2814	Major facilitator Superfamily
KCX77_16425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCX77_16430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCX77_16435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCX77_16440	COG2356	endonuclease I
KCX77_16450	COG3842	ATPase activity
KCX77_16455	COG2188	Transcriptional regulator
KCX77_16460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCX77_16465	COG0395	ABC-type sugar transport system, permease component
KCX77_16470	COG1175	transmembrane transport
KCX77_16475	COG1653	transport
KCX77_16480	COG2222	sugar isomerase
KCX77_16485	COG0322	excinuclease ABC activity
KCX77_16490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCX77_16495	COG0719	Fe-S assembly protein
KCX77_16500	COG0822	iron-sulfur transferase activity
KCX77_16505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCX77_16510	COG0719	Fe-S assembly protein
KCX77_16515	COG0396	ATPase activity
KCX77_16525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCX77_16530	COG1464	Belongs to the NlpA lipoprotein family
KCX77_16535	COG2011	ABC-type metal ion transport system permease component
KCX77_16540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCX77_16550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCX77_16555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCX77_16565	COG0509	glycine decarboxylation via glycine cleavage system
KCX77_16570	COG1393	Belongs to the ArsC family
KCX77_16575	COG1960	acyl-CoA dehydrogenase activity
KCX77_16580	COG0183	Belongs to the thiolase family
KCX77_16585	COG1024	Enoyl-CoA hydratase
KCX77_16585	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCX77_16605	COG5577	PFAM Coat F domain
KCX77_16610	COG1846	Transcriptional regulator
KCX77_16615	COG0477	Major facilitator Superfamily
KCX77_16625	COG1120	ATPase activity
KCX77_16640	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_16645	COG0783	Belongs to the Dps family
KCX77_16650	COG0488	(ABC) transporter
KCX77_16665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCX77_16670	COG0745	RESPONSE REGULATOR receiver
KCX77_16675	COG2205	protein histidine kinase activity
KCX77_16675	COG2770	Histidine kinase
KCX77_16685	COG1309	transcriptional regulator
KCX77_16690	COG0114	fumarate hydratase activity
KCX77_16700	COG0697	spore germination
KCX77_16705	COG0814	amino acid
KCX77_16715	COG2197	response regulator
KCX77_16720	COG4585	Histidine kinase
KCX77_16725	COG4758	membrane
KCX77_16730	COG3595	metallopeptidase activity
KCX77_16735	COG1842	Phage shock protein A
KCX77_16740	COG4758	membrane
KCX77_16745	COG2814	Major facilitator Superfamily
KCX77_16750	COG2096	Adenosyltransferase
KCX77_16755	COG1120	ATPase activity
KCX77_16760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_16765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_16770	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_16775	COG3386	PFAM SMP-30 Gluconolaconase
KCX77_16780	COG2205	protein histidine kinase activity
KCX77_16785	COG0745	RESPONSE REGULATOR receiver
KCX77_16795	COG1191	sigma factor activity
KCX77_16805	COG2140	Oxalate decarboxylase
KCX77_16815	COG0577	efflux transmembrane transporter activity
KCX77_16820	COG1136	(ABC) transporter
KCX77_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCX77_16830	COG1120	ATPase activity
KCX77_16835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_16840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCX77_16845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_16855	COG0531	amino acid
KCX77_16870	COG1988	membrane-bound metal-dependent
KCX77_16875	COG1368	sulfuric ester hydrolase activity
KCX77_16880	COG1910	domain protein
KCX77_16885	COG0725	ABC transporter, periplasmic molybdate-binding protein
KCX77_16890	COG4149	molybdate abc transporter
KCX77_16900	COG0656	L-ascorbic acid biosynthetic process
KCX77_16920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCX77_16925	COG3973	AAA domain
KCX77_16930	COG2860	membrane
KCX77_16940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KCX77_16945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCX77_16950	COG2217	Heavy metal translocating P-type atpase
KCX77_16955	COG2217	Heavy metal translocating P-type atpase
KCX77_16960	COG2608	mercury ion transmembrane transporter activity
KCX77_16965	COG1937	Protein conserved in bacteria
KCX77_16970	COG0673	inositol 2-dehydrogenase activity
KCX77_16980	COG1289	transmembrane transporter activity
KCX77_16985	COG1846	Transcriptional regulator
KCX77_16995	COG2076	Multidrug Resistance protein
KCX77_17000	COG1309	transcriptional regulator
KCX77_17005	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_17020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCX77_17025	COG0557	exoribonuclease II activity
KCX77_17030	COG1647	Serine aminopeptidase, S33
KCX77_17035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCX77_17040	COG1476	TRANSCRIPTIONal
KCX77_17045	COG1396	sequence-specific DNA binding
KCX77_17050	COG1396	sequence-specific DNA binding
KCX77_17055	COG1733	regulation of RNA biosynthetic process
KCX77_17060	COG0840	transmembrane signaling receptor activity
KCX77_17065	COG1174	glycine betaine transport
KCX77_17070	COG1732	Glycine betaine
KCX77_17075	COG1174	glycine betaine transport
KCX77_17080	COG0517	IMP dehydrogenase activity
KCX77_17080	COG1125	glycine betaine transport
KCX77_17085	COG1510	regulation of RNA biosynthetic process
KCX77_17090	COG1174	glycine betaine transport
KCX77_17095	COG1732	Glycine betaine
KCX77_17100	COG1174	glycine betaine transport
KCX77_17105	COG1125	glycine betaine transport
KCX77_17105	COG0517	IMP dehydrogenase activity
KCX77_17110	COG1510	regulation of RNA biosynthetic process
KCX77_17120	COG3064	Membrane
KCX77_17125	COG4640	response to antibiotic
KCX77_17130	COG0456	acetyltransferase
KCX77_17145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KCX77_17165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_17170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCX77_17180	COG2234	aminopeptidase activity
KCX77_17190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCX77_17200	COG0126	phosphoglycerate kinase activity
KCX77_17205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCX77_17210	COG2390	Transcriptional regulator
KCX77_17215	COG2814	Major facilitator Superfamily
KCX77_17220	COG1609	Transcriptional regulator
KCX77_17225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCX77_17230	COG0583	DNA-binding transcription factor activity
KCX77_17235	COG0697	spore germination
KCX77_17240	COG1113	amino acid transport
KCX77_17245	COG3858	chitin binding
KCX77_17250	COG1556	Lactate utilization protein
KCX77_17255	COG1139	Iron-sulfur cluster binding protein
KCX77_17260	COG0247	lactate metabolic process
KCX77_17265	COG2208	phosphoserine phosphatase activity
KCX77_17270	COG2186	Transcriptional regulator
KCX77_17275	COG1620	l-lactate permease
KCX77_17280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KCX77_17290	COG5039	Polysaccharide pyruvyl transferase
KCX77_17295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCX77_17300	COG0110	maltose O-acetyltransferase activity
KCX77_17305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KCX77_17310	COG2244	polysaccharide biosynthetic process
KCX77_17315	COG1216	Glycosyl transferase, family 2
KCX77_17320	COG5039	Polysaccharide pyruvyl transferase
KCX77_17325	COG1216	Glycosyl transferase, family 2
KCX77_17335	COG0438	transferase activity, transferring glycosyl groups
KCX77_17340	COG1215	transferase activity, transferring glycosyl groups
KCX77_17345	COG0438	transferase activity, transferring glycosyl groups
KCX77_17350	COG1086	Polysaccharide biosynthesis protein
KCX77_17355	COG0489	protein tyrosine kinase activity
KCX77_17360	COG3944	biosynthesis protein
KCX77_17365	COG1396	sequence-specific DNA binding
KCX77_17370	COG2272	Belongs to the type-B carboxylesterase lipase family
KCX77_17385	COG0640	Transcriptional regulator
KCX77_17400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCX77_17405	COG0583	DNA-binding transcription factor activity
KCX77_17415	COG1621	beta-fructofuranosidase activity
KCX77_17420	COG1621	beta-fructofuranosidase activity
KCX77_17425	COG0531	amino acid
KCX77_17430	COG1309	transcriptional regulator
KCX77_17435	COG2076	Multidrug Resistance protein
KCX77_17440	COG2076	Multidrug Resistance protein
KCX77_17445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_17470	COG1611	Belongs to the LOG family
KCX77_17475	COG1694	Mazg nucleotide pyrophosphohydrolase
KCX77_17480	COG0659	secondary active sulfate transmembrane transporter activity
KCX77_17485	COG0288	reversible hydration of carbon dioxide
KCX77_17490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCX77_17495	COG0577	efflux transmembrane transporter activity
KCX77_17500	COG1136	(ABC) transporter
KCX77_17505	COG5002	protein histidine kinase activity
KCX77_17510	COG0745	RESPONSE REGULATOR receiver
KCX77_17515	COG4290	ribonuclease
KCX77_17520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KCX77_17525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_17535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KCX77_17540	COG1660	Displays ATPase and GTPase activities
KCX77_17545	COG1051	belongs to the nudix hydrolase family
KCX77_17550	COG0492	ferredoxin-NADP+ reductase activity
KCX77_17555	COG0791	NLP P60 protein
KCX77_17555	COG3883	PFAM NLP P60 protein
KCX77_17560	COG0457	Tetratricopeptide repeat
KCX77_17565	COG1132	(ABC) transporter
KCX77_17580	COG1247	-acetyltransferase
KCX77_17585	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_17595	COG0140	phosphoribosyl-ATP diphosphatase activity
KCX77_17595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCX77_17600	COG0107	imidazoleglycerol-phosphate synthase activity
KCX77_17605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCX77_17615	COG0131	Imidazoleglycerol-phosphate dehydratase
KCX77_17620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCX77_17625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCX77_17630	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCX77_17635	COG4990	cell redox homeostasis
KCX77_17640	COG5297	Belongs to the glycosyl hydrolase family 6
KCX77_17645	COG0110	maltose O-acetyltransferase activity
KCX77_17650	COG0546	phosphoglycolate phosphatase activity
KCX77_17655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KCX77_17660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCX77_17665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCX77_17670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCX77_17680	COG2188	Transcriptional regulator
KCX77_17685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KCX77_17690	COG1950	PFAM Membrane protein of
KCX77_17695	COG1983	PspC domain protein
KCX77_17700	COG3595	metallopeptidase activity
KCX77_17715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCX77_17725	COG4897	Protein conserved in bacteria
KCX77_17730	COG0574	Belongs to the PEP-utilizing enzyme family
KCX77_17730	COG3848	Pyruvate phosphate dikinase
KCX77_17735	COG1309	transcriptional regulator
KCX77_17740	COG2814	Major facilitator Superfamily
KCX77_17750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCX77_17760	COG3409	Peptidoglycan-binding domain 1 protein
KCX77_17760	COG0793	Belongs to the peptidase S41A family
KCX77_17765	COG2177	Part of the ABC transporter FtsEX involved in
KCX77_17770	COG2884	Cell division ATP-binding protein ftsE
KCX77_17775	COG2010	Cytochrome c
KCX77_17780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_17790	COG0653	protein targeting
KCX77_17795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCX77_17810	COG1516	flagellar protein fliS
KCX77_17815	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCX77_17820	COG1334	flagellar protein FlaG
KCX77_17825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCX77_17830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCX77_17835	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KCX77_17845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCX77_17850	COG1256	bacterial-type flagellum assembly
KCX77_17850	COG4786	Flagellar basal body rod
KCX77_17855	COG3418	PFAM FlgN family protein
KCX77_17860	COG2747	anti-sigma28 factor FlgM
KCX77_17870	COG1040	competence protein
KCX77_17880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCX77_17885	COG1307	EDD domain protein, DegV family
KCX77_17890	COG2197	response regulator
KCX77_17895	COG4585	Histidine kinase
KCX77_17900	COG1739	Uncharacterized protein family UPF0029
KCX77_17905	COG1316	TRANSCRIPTIONal
KCX77_17910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCX77_17915	COG0438	transferase activity, transferring glycosyl groups
KCX77_17920	COG1215	transferase activity, transferring glycosyl groups
KCX77_17925	COG3206	protein involved in exopolysaccharide biosynthesis
KCX77_17930	COG3307	-O-antigen
KCX77_17935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCX77_17940	COG0297	glycogen (starch) synthase activity
KCX77_17940	COG0438	transferase activity, transferring glycosyl groups
KCX77_17945	COG2244	polysaccharide biosynthetic process
KCX77_17960	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCX77_17960	COG2247	cell wall binding repeat
KCX77_17965	COG2385	sporulation resulting in formation of a cellular spore
KCX77_17965	COG2247	cell wall binding repeat
KCX77_17975	COG1316	TRANSCRIPTIONal
KCX77_17980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCX77_17985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCX77_17990	COG1134	teichoic acid transport
KCX77_17995	COG1682	transport, permease protein
KCX77_18000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KCX77_18010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KCX77_18015	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KCX77_18020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KCX77_18025	COG4193	domain, Protein
KCX77_18030	COG1482	cell wall glycoprotein biosynthetic process
KCX77_18035	COG0697	spore germination
KCX77_18040	COG0814	amino acid
KCX77_18055	COG2814	Major facilitator Superfamily
KCX77_18060	COG1316	TRANSCRIPTIONal
KCX77_18065	COG0561	phosphatase activity
KCX77_18070	COG0791	NLP P60 protein
KCX77_18080	COG2843	Capsule synthesis protein
KCX77_18090	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCX77_18095	COG0697	spore germination
KCX77_18100	COG0531	amino acid
KCX77_18110	COG1609	Transcriptional regulator
KCX77_18115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCX77_18120	COG1869	D-ribose catabolic process
KCX77_18125	COG1129	ABC transporter
KCX77_18130	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCX77_18135	COG1879	ABC-type sugar transport system periplasmic component
KCX77_18140	COG3103	Sh3 type 3 domain protein
KCX77_18150	COG2249	NAD(P)H dehydrogenase (quinone) activity
KCX77_18155	COG3527	Alpha-acetolactate decarboxylase
KCX77_18160	COG0028	Belongs to the TPP enzyme family
KCX77_18165	COG0583	DNA-binding transcription factor activity
KCX77_18170	COG5337	Spore coat protein CotH
KCX77_18180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCX77_18185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_18200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KCX77_18210	COG0405	Gamma-glutamyltransferase
KCX77_18215	COG1522	sequence-specific DNA binding
KCX77_18220	COG2059	Chromate
KCX77_18225	COG2059	Chromate
KCX77_18235	COG0655	NAD(P)H dehydrogenase (quinone) activity
KCX77_18240	COG0583	DNA-binding transcription factor activity
KCX77_18285	COG5444	nuclease activity
KCX77_18305	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCX77_18315	COG4464	protein tyrosine phosphatase activity
KCX77_18320	COG0489	protein tyrosine kinase activity
KCX77_18325	COG3944	biosynthesis protein
KCX77_18335	COG4715	Zinc finger, swim domain protein
KCX77_18340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCX77_18345	COG0561	phosphatase activity
KCX77_18350	COG1349	DNA-binding transcription factor activity
KCX77_18355	COG0629	single-stranded DNA binding
KCX77_18370	COG1970	mechanosensitive ion channel activity
KCX77_18380	COG0457	Tetratricopeptide repeat
KCX77_18385	COG4786	Flagellar basal body rod
KCX77_18390	COG4786	Flagellar basal body rod
KCX77_18395	COG1077	Cell shape determining protein MreB Mrl
KCX77_18400	COG1609	Transcriptional regulator
KCX77_18410	COG1846	Transcriptional regulator
KCX77_18415	COG2814	Major facilitator Superfamily
KCX77_18425	COG0477	Major facilitator Superfamily
KCX77_18430	COG1335	isochorismatase
KCX77_18440	COG0004	ammonium transporteR
KCX77_18445	COG0347	Belongs to the P(II) protein family
KCX77_18450	COG0772	Belongs to the SEDS family
KCX77_18455	COG0671	phosphoesterase, PA-phosphatase related
KCX77_18465	COG0739	heme binding
KCX77_18470	COG1247	-acetyltransferase
KCX77_18480	COG1086	Polysaccharide biosynthesis protein
KCX77_18485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCX77_18490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCX77_18495	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KCX77_18510	COG2089	acid synthase
KCX77_18520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCX77_18525	COG0789	Transcriptional regulator
KCX77_18535	COG2910	NAD(P)H-binding
KCX77_18540	COG1959	2 iron, 2 sulfur cluster binding
KCX77_18545	COG0804	urea catabolic process
KCX77_18555	COG0831	urea catabolic process
KCX77_18560	COG3237	CsbD-like
KCX77_18565	COG1994	Peptidase M50
KCX77_18570	COG0457	Tetratricopeptide repeat
KCX77_18580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KCX77_18590	COG2304	oxidoreductase activity
KCX77_18595	COG2304	oxidoreductase activity
KCX77_18600	COG2385	sporulation resulting in formation of a cellular spore
KCX77_18605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCX77_18615	COG4836	Membrane
KCX77_18625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCX77_18630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCX77_18635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCX77_18645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCX77_18650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCX77_18670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCX77_18675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCX77_18680	COG4475	Protein of unknown function (DUF436)
KCX77_18685	COG0698	ribose 5-phosphate isomerase
KCX77_18690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCX77_18695	COG1971	Probably functions as a manganese efflux pump
KCX77_18700	COG0009	L-threonylcarbamoyladenylate synthase
KCX77_18705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KCX77_18725	COG2890	protein-(glutamine-N5) methyltransferase activity
KCX77_18730	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCX77_18735	COG0346	lactoylglutathione lyase activity
KCX77_18740	COG0789	Transcriptional regulator
KCX77_18745	COG0679	Auxin Efflux Carrier
KCX77_18750	COG0281	malic enzyme
KCX77_18760	COG0254	rRNA binding
KCX77_18765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCX77_18770	COG1494	fructose-1,6-bisphosphatase
KCX77_18775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCX77_18785	COG0191	fructose-bisphosphate aldolase activity
KCX77_18790	COG2204	response regulator
KCX77_18795	COG4821	SIS domain
KCX77_18800	COG0504	CTP synthase activity
KCX77_18805	COG3343	RNA polymerase activity
KCX77_18810	COG1960	acyl-CoA dehydrogenase activity
KCX77_18815	COG2181	nitrate reductase activity
KCX77_18815	COG0247	lactate metabolic process
KCX77_18820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCX77_18825	COG4294	response to UV
KCX77_18835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCX77_18840	COG1132	(ABC) transporter
KCX77_18845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCX77_18850	COG2181	nitrate reductase activity
KCX77_18855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KCX77_18860	COG1140	nitrate reductase beta subunit
KCX77_18865	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KCX77_18870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCX77_18880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCX77_18885	COG2223	nitrite transmembrane transporter activity
KCX77_18890	COG0018	arginyl-trna synthetase
KCX77_18895	COG4506	Protein conserved in bacteria
KCX77_18905	COG0535	radical SAM domain protein
KCX77_18915	COG1131	(ABC) transporter
KCX77_18925	COG0612	Peptidase, M16
KCX77_18940	COG3391	amine dehydrogenase activity
KCX77_18945	COG3391	amine dehydrogenase activity
KCX77_18950	COG1388	LysM domain
KCX77_18965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCX77_18970	COG0010	Belongs to the arginase family
KCX77_18975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KCX77_18980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCX77_18995	COG1994	Peptidase M50
KCX77_19000	COG1942	4-Oxalocrotonate Tautomerase
KCX77_19005	COG1846	Transcriptional regulator
KCX77_19010	COG0531	amino acid
KCX77_19015	COG3465	dGTPase activity
KCX77_19020	COG1078	dGTPase activity
KCX77_19025	COG4844	belongs to the
KCX77_19035	COG0697	spore germination
KCX77_19040	COG0095	Lipoate-protein ligase
KCX77_19045	COG0583	DNA-binding transcription factor activity
KCX77_19055	COG0280	phosphate acetyltransferase
KCX77_19060	COG3253	May function as heme-dependent peroxidase
KCX77_19065	COG2814	Major facilitator Superfamily
KCX77_19070	COG2814	Major facilitator Superfamily
KCX77_19080	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KCX77_19085	COG1091	dTDP-4-dehydrorhamnose reductase activity
KCX77_19090	COG1088	dTDP-glucose 4,6-dehydratase activity
KCX77_19095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCX77_19100	COG0456	acetyltransferase
KCX77_19105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KCX77_19110	COG0463	Glycosyl transferase, family 2
KCX77_19120	COG2363	Small membrane protein
KCX77_19125	COG2233	PERMEase
KCX77_19135	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_19140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCX77_19145	COG1216	Glycosyl transferase, family 2
KCX77_19155	COG0351	phosphomethylpyrimidine kinase
KCX77_19165	COG0110	maltose O-acetyltransferase activity
KCX77_19170	COG1621	beta-fructofuranosidase activity
KCX77_19175	COG1263	PTS System
KCX77_19175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_19185	COG3711	transcriptional antiterminator
KCX77_19195	COG1404	Belongs to the peptidase S8 family
KCX77_19205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCX77_19210	COG0778	Nitroreductase
KCX77_19215	COG0772	Belongs to the SEDS family
KCX77_19230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCX77_19240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCX77_19245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCX77_19250	COG2261	transglycosylase associated protein
KCX77_19255	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KCX77_19260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCX77_19265	COG2246	polysaccharide biosynthetic process
KCX77_19270	COG1309	transcriptional regulator
KCX77_19290	COG3162	membrane
KCX77_19295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCX77_19300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KCX77_19305	COG0352	thiamine-phosphate diphosphorylase activity
KCX77_19310	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KCX77_19315	COG0583	DNA-binding transcription factor activity
KCX77_19325	COG1346	cytolysis
KCX77_19330	COG4895	conserved protein (DUF2196)
KCX77_19335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCX77_19340	COG0346	lactoylglutathione lyase activity
KCX77_19345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCX77_19350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_19350	COG1263	PTS System
KCX77_19355	COG3711	transcriptional antiterminator
KCX77_19360	COG1442	glycosyl transferase family 8
KCX77_19365	COG5522	Integral membrane protein (intg_mem_TP0381)
KCX77_19370	COG2234	aminopeptidase activity
KCX77_19375	COG0457	Tetratricopeptide repeat
KCX77_19380	COG1846	Transcriptional regulator
KCX77_19385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCX77_19390	COG2357	RelA SpoT domain protein
KCX77_19395	COG1575	Belongs to the MenA family. Type 1 subfamily
KCX77_19400	COG0569	domain protein
KCX77_19410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCX77_19415	COG1696	Membrane protein involved in D-alanine export
KCX77_19425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCX77_19430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCX77_19435	COG1486	melibiose metabolic process
KCX77_19440	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCX77_19445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCX77_19450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCX77_19455	COG3711	transcriptional antiterminator
KCX77_19455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCX77_19465	COG2094	Belongs to the DNA glycosylase MPG family
KCX77_19470	COG0753	catalase activity
KCX77_19475	COG2814	Major facilitator Superfamily
KCX77_19480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KCX77_19485	COG1131	(ABC) transporter
KCX77_19505	COG1595	DNA-templated transcription, initiation
KCX77_19510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KCX77_19515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCX77_19520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCX77_19525	COG4988	ABC transporter
KCX77_19530	COG1294	oxidase, subunit
KCX77_19535	COG1271	oxidase subunit
KCX77_19540	COG3493	citrate carrier protein
KCX77_19550	COG0726	polysaccharide deacetylase
KCX77_19555	COG3842	ATPase activity
KCX77_19560	COG2508	Transcriptional regulator
KCX77_19565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCX77_19575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCX77_19585	COG2195	Cleaves the N-terminal amino acid of tripeptides
KCX77_19600	COG4894	glucomannan catabolic process
KCX77_19605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCX77_19610	COG3290	protein histidine kinase activity
KCX77_19610	COG3829	transcription factor binding
KCX77_19615	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_19620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KCX77_19625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCX77_19630	COG2610	gluconate transmembrane transporter activity
KCX77_19635	COG0500	methyltransferase
KCX77_19640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCX77_19655	COG0753	catalase activity
KCX77_19655	COG0693	protein deglycase activity
KCX77_19660	COG2851	Citrate transporter
KCX77_19670	COG3711	transcriptional antiterminator
KCX77_19680	COG2270	Major facilitator Superfamily
KCX77_19685	COG0513	Belongs to the DEAD box helicase family
KCX77_19690	COG0346	lactoylglutathione lyase activity
KCX77_19695	COG1357	PFAM Pentapeptide repeats (8 copies)
KCX77_19700	COG2755	lipolytic protein G-D-S-L family
KCX77_19700	COG3401	FG-GAP repeat protein
KCX77_19775	COG3866	Pectate lyase
KCX77_19780	COG0697	spore germination
KCX77_19785	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_19805	COG0589	response to stress
KCX77_19810	COG2723	6-phospho-beta-galactosidase activity
KCX77_19815	COG1263	PTS System
KCX77_19815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCX77_19815	COG2190	(PTS) system
KCX77_19835	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCX77_19845	COG3507	Belongs to the glycosyl hydrolase 43 family
KCX77_19910	COG2986	histidine ammonia-lyase
KCX77_19915	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCX77_19920	COG1228	amidohydrolase
KCX77_19925	COG0010	Belongs to the arginase family
KCX77_19930	COG0833	amino acid
KCX77_19935	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KCX77_19940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCX77_19945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCX77_19950	COG2390	Transcriptional regulator
KCX77_19960	COG3192	ethanolamine utilization protein
KCX77_19965	COG1940	carbohydrate kinase activity
KCX77_19970	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KCX77_19975	COG0561	phosphatase activity
KCX77_20000	COG5294	Protein conserved in bacteria
KCX77_20005	COG0577	efflux transmembrane transporter activity
KCX77_20010	COG1136	(ABC) transporter
KCX77_20015	COG2205	protein histidine kinase activity
KCX77_20020	COG0745	RESPONSE REGULATOR receiver
KCX77_20030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCX77_20045	COG1082	Xylose isomerase domain protein TIM barrel
KCX77_20050	COG0673	inositol 2-dehydrogenase activity
KCX77_20055	COG2814	Major facilitator Superfamily
KCX77_20060	COG1082	Xylose isomerase domain protein TIM barrel
KCX77_20065	COG3962	Belongs to the TPP enzyme family
KCX77_20070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCX77_20085	COG1349	DNA-binding transcription factor activity
KCX77_20090	COG0667	Aldo Keto reductase
KCX77_20110	COG2814	Major facilitator Superfamily
KCX77_20115	COG0326	Molecular chaperone. Has ATPase activity
KCX77_20120	COG1028	Short-chain dehydrogenase reductase Sdr
KCX77_20125	COG1309	transcriptional regulator
KCX77_20130	COG1012	belongs to the aldehyde dehydrogenase family
KCX77_20140	COG1714	RDD family
KCX77_20145	COG2311	Membrane
KCX77_20155	COG1309	transcriptional regulator
KCX77_20190	COG5039	Polysaccharide pyruvyl transferase
KCX77_20195	COG1929	Belongs to the glycerate kinase type-1 family
KCX77_20200	COG2610	gluconate transmembrane transporter activity
KCX77_20205	COG3835	regulator
KCX77_20210	COG1802	Transcriptional regulator
KCX77_20215	COG1070	Carbohydrate kinase
KCX77_20220	COG2610	gluconate transmembrane transporter activity
KCX77_20225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCX77_20230	COG0450	alkyl hydroperoxide reductase
KCX77_20235	COG3634	alkyl hydroperoxide reductase activity
KCX77_20245	COG1113	amino acid transport
KCX77_20270	COG1131	(ABC) transporter
KCX77_20275	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KCX77_20285	COG2323	membrane
KCX77_20315	COG2003	Belongs to the UPF0758 family
KCX77_20350	COG1192	Involved in chromosome partitioning
KCX77_20355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCX77_20365	COG1063	alcohol dehydrogenase
KCX77_20375	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KCX77_20385	COG0010	Belongs to the arginase family
KCX77_20390	COG0833	amino acid
KCX77_20395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCX77_20400	COG3829	transcription factor binding
KCX77_20410	COG0488	(ABC) transporter
KCX77_20425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCX77_20430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCX77_20435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KCX77_20440	COG4853	Protein conserved in bacteria
KCX77_20445	COG4863	YycH protein
KCX77_20450	COG5002	protein histidine kinase activity
KCX77_20455	COG0745	RESPONSE REGULATOR receiver
KCX77_20485	COG0346	lactoylglutathione lyase activity
KCX77_20490	COG0305	Participates in initiation and elongation during chromosome replication
KCX77_20505	COG3093	addiction module antidote protein HigA
KCX77_20510	COG2807	transmembrane transport
KCX77_20520	COG0359	binds to the 23S rRNA
KCX77_20525	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KCX77_20530	COG4241	membrane
KCX77_20540	COG5577	PFAM Coat F domain
KCX77_20545	COG1733	regulation of RNA biosynthetic process
KCX77_20560	COG2271	Major facilitator Superfamily
KCX77_20565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCX77_20575	COG0473	3-isopropylmalate dehydrogenase activity
KCX77_20580	COG1802	Transcriptional regulator
KCX77_20585	COG0789	Transcriptional regulator
KCX77_20585	COG4978	Transcriptional regulator
KCX77_20590	COG3764	Sortase (surface protein transpeptidase)
KCX77_20615	COG0745	RESPONSE REGULATOR receiver
KCX77_20620	COG2205	protein histidine kinase activity
KCX77_20635	COG0789	Transcriptional regulator
KCX77_20635	COG4978	Transcriptional regulator
KCX77_20640	COG1811	Na channel or pump
KCX77_20645	COG1331	Highly conserved protein containing a thioredoxin domain
KCX77_20655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCX77_20660	COG1331	Highly conserved protein containing a thioredoxin domain
KCX77_20665	COG0477	Major facilitator Superfamily
KCX77_20665	COG2814	Major facilitator Superfamily
KCX77_20670	COG0346	lactoylglutathione lyase activity
KCX77_20675	COG1609	Transcriptional regulator
KCX77_20680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCX77_20685	COG2169	Transcriptional regulator
KCX77_20690	COG0708	Exodeoxyribonuclease III
KCX77_20695	COG0697	spore germination
KCX77_20700	COG1802	Transcriptional regulator
KCX77_20715	COG0629	single-stranded DNA binding
KCX77_20720	COG0360	Binds together with S18 to 16S ribosomal RNA
KCX77_20725	COG0012	GTP binding
KCX77_20730	COG0243	molybdopterin cofactor binding
KCX77_20735	COG4481	Protein conserved in bacteria
KCX77_20740	COG3949	Membrane
KCX77_20750	COG1475	DNA binding
KCX77_20755	COG1192	Involved in chromosome partitioning
KCX77_20765	COG1475	DNA binding
KCX77_20770	COG0357	Ribosomal RNA small subunit methyltransferase G
KCX77_20775	COG0445	tRNA wobble uridine modification
KCX77_20785	COG1847	R3H domain protein
KCX77_20790	COG0706	membrane insertase activity
KCX77_20795	COG0594	ribonuclease P activity