locus-tag	class	description
TD68_00015	COG1785	Belongs to the alkaline phosphatase family
TD68_00025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_00030	COG0517	IMP dehydrogenase activity
TD68_00030	COG1125	glycine betaine transport
TD68_00035	COG1174	glycine betaine transport
TD68_00040	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_00045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_00060	COG2814	Major facilitator Superfamily
TD68_00065	COG2186	Transcriptional regulator
TD68_00070	COG2807	transmembrane transport
TD68_00085	COG1378	Sugar-specific transcriptional regulator TrmB
TD68_00130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TD68_00135	COG0802	atpase or kinase
TD68_00140	COG1214	PFAM Peptidase M22, glycoprotease
TD68_00145	COG0456	acetyltransferase
TD68_00150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TD68_00155	COG0488	(ABC) transporter
TD68_00160	COG0315	cyclic pyranopterin monophosphate synthase activity
TD68_00170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TD68_00175	COG0805	protein transport
TD68_00185	COG1266	CAAX protease self-immunity
TD68_00190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TD68_00215	COG2197	response regulator
TD68_00220	COG0457	Tetratricopeptide repeat
TD68_00225	COG1063	alcohol dehydrogenase
TD68_00230	COG2211	Major facilitator Superfamily
TD68_00235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_00240	COG1842	Phage shock protein A
TD68_00245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TD68_00250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TD68_00255	COG4260	virion core protein, lumpy skin disease virus
TD68_00265	COG1595	DNA-templated transcription, initiation
TD68_00275	COG0778	Nitroreductase
TD68_00280	COG1846	Transcriptional regulator
TD68_00285	COG2814	Major facilitator Superfamily
TD68_00290	COG1063	alcohol dehydrogenase
TD68_00295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TD68_00300	COG0823	Involved in the tonB-independent uptake of proteins
TD68_00310	COG2267	carboxylic ester hydrolase activity
TD68_00320	COG2132	Multicopper oxidase
TD68_00325	COG1113	amino acid transport
TD68_00335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD68_00340	COG0714	Associated with various cellular activities
TD68_00345	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
TD68_00350	COG1305	Transglutaminase-like
TD68_00355	COG0519	Catalyzes the synthesis of GMP from XMP
TD68_00355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TD68_00370	COG2252	PERMEase
TD68_00375	COG3064	Membrane
TD68_00380	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
TD68_00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TD68_00395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TD68_00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TD68_00405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TD68_00410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TD68_00415	COG0047	phosphoribosylformylglycinamidine synthase activity
TD68_00420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TD68_00425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TD68_00435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TD68_00440	COG0138	bifunctional purine biosynthesis protein purh
TD68_00445	COG0151	Belongs to the GarS family
TD68_00450	COG1522	sequence-specific DNA binding
TD68_00455	COG0531	amino acid
TD68_00465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TD68_00470	COG1470	cell adhesion involved in biofilm formation
TD68_00475	COG4496	protein, YerC YecD
TD68_00480	COG0069	glutamate synthase activity
TD68_00485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TD68_00490	COG0210	DNA helicase
TD68_00495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TD68_00500	COG4851	CamS sex pheromone cAM373 precursor
TD68_00505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_00510	COG1285	pathogenesis
TD68_00515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_00525	COG0154	amidase activity
TD68_00535	COG1309	transcriptional regulator
TD68_00540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TD68_00545	COG1597	lipid kinase activity
TD68_00550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD68_00555	COG2197	response regulator
TD68_00565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_00575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_00585	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_00590	COG1131	(ABC) transporter
TD68_00615	COG0457	Tetratricopeptide repeat
TD68_00630	COG3391	amine dehydrogenase activity
TD68_00635	COG3391	amine dehydrogenase activity
TD68_00645	COG0457	Tetratricopeptide repeat
TD68_00665	COG3546	catalase activity
TD68_00670	COG0454	-acetyltransferase
TD68_00680	COG5578	integral membrane protein
TD68_00685	COG2972	Histidine kinase
TD68_00690	COG2207	Transcriptional regulator
TD68_00690	COG4753	response regulator
TD68_00695	COG1653	transport
TD68_00700	COG1175	transmembrane transport
TD68_00705	COG0395	ABC-type sugar transport system, permease component
TD68_00710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TD68_00715	COG2207	Transcriptional regulator
TD68_00720	COG2755	lipolytic protein G-D-S-L family
TD68_00730	COG5578	integral membrane protein
TD68_00735	COG3401	FG-GAP repeat protein
TD68_00740	COG3401	FG-GAP repeat protein
TD68_00745	COG2755	lipolytic protein G-D-S-L family
TD68_00750	COG1874	Beta-galactosidase
TD68_00760	COG1653	transport
TD68_00765	COG4209	transmembrane transport
TD68_00770	COG0395	ABC-type sugar transport system, permease component
TD68_00775	COG1486	melibiose metabolic process
TD68_00780	COG2323	membrane
TD68_00785	COG2329	Antibiotic biosynthesis monooxygenase
TD68_00790	COG0346	lactoylglutathione lyase activity
TD68_00795	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_00800	COG0196	riboflavin kinase activity
TD68_00805	COG0670	Belongs to the BI1 family
TD68_00815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_00815	COG2124	cytochrome p450
TD68_00830	COG1131	(ABC) transporter
TD68_00840	COG1368	sulfuric ester hydrolase activity
TD68_00845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TD68_00850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_00855	COG1442	glycosyl transferase family 8
TD68_00860	COG1216	Glycosyl transferase, family 2
TD68_00865	COG1442	glycosyl transferase family 8
TD68_00870	COG2223	nitrite transmembrane transporter activity
TD68_00875	COG0531	amino acid
TD68_00880	COG1012	belongs to the aldehyde dehydrogenase family
TD68_00885	COG0840	transmembrane signaling receptor activity
TD68_00890	COG0463	Glycosyl transferase, family 2
TD68_00895	COG0488	(ABC) transporter
TD68_00900	COG0789	Transcriptional regulator
TD68_00905	COG2814	Major facilitator Superfamily
TD68_00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_00915	COG0488	(ABC) transporter
TD68_00920	COG0513	Belongs to the DEAD box helicase family
TD68_00925	COG0457	Tetratricopeptide repeat
TD68_00930	COG2130	NADP-dependent
TD68_00935	COG1120	ATPase activity
TD68_00940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_00945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_00950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TD68_00965	COG3866	Pectate lyase
TD68_00975	COG0471	metal ion transport
TD68_00995	COG3290	protein histidine kinase activity
TD68_01000	COG4565	transcriptional regulatory protein
TD68_01005	COG3181	Tripartite tricarboxylate transporter family receptor
TD68_01010	COG2851	Citrate transporter
TD68_01015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_01020	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
TD68_01025	COG1254	Belongs to the acylphosphatase family
TD68_01030	COG2258	MOSC domain
TD68_01040	COG0024	Methionine aminopeptidase
TD68_01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_01045	COG1263	PTS System
TD68_01050	COG1368	sulfuric ester hydrolase activity
TD68_01060	COG1115	amino acid carrier protein
TD68_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_01065	COG1263	PTS System
TD68_01070	COG0366	Alpha amylase catalytic
TD68_01075	COG2188	Transcriptional regulator
TD68_01080	COG0778	Nitroreductase
TD68_01085	COG0737	Belongs to the 5'-nucleotidase family
TD68_01090	COG0693	protein deglycase activity
TD68_01095	COG1609	Transcriptional regulator
TD68_01100	COG2814	Major facilitator Superfamily
TD68_01105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TD68_01115	COG2814	Major facilitator Superfamily
TD68_01120	COG4840	Belongs to the UPF0435 family
TD68_01125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_01130	COG4980	gas vesicle protein
TD68_01135	COG1295	ribonuclease BN
TD68_01140	COG0477	Major facilitator Superfamily
TD68_01145	COG0387	Pfam Sodium calcium exchanger
TD68_01155	COG0668	transmembrane transport
TD68_01160	COG0535	radical SAM domain protein
TD68_01170	COG0726	polysaccharide deacetylase
TD68_01175	COG2084	Dehydrogenase
TD68_01185	COG0598	Magnesium transport protein CorA
TD68_01190	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TD68_01200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD68_01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD68_01210	COG4637	Psort location Cytoplasmic, score
TD68_01215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_01220	COG0022	dehydrogenase e1 component
TD68_01225	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_01235	COG3284	Transcriptional regulator
TD68_01245	COG1742	UPF0060 membrane protein
TD68_01265	COG4842	Belongs to the WXG100 family
TD68_01270	COG1486	melibiose metabolic process
TD68_01275	COG1737	Transcriptional regulator
TD68_01280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_01280	COG1263	PTS System
TD68_01285	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_01290	COG1132	(ABC) transporter
TD68_01295	COG1132	(ABC) transporter
TD68_01300	COG2259	Doxx family
TD68_01305	COG2514	catechol 2,3-dioxygenase activity
TD68_01310	COG0842	Transport permease protein
TD68_01315	COG1695	Transcriptional regulator
TD68_01320	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
TD68_01325	COG2732	(Barnase) inhibitor
TD68_01330	COG0604	alcohol dehydrogenase
TD68_01335	COG2318	DinB family
TD68_01340	COG2814	Major facilitator Superfamily
TD68_01345	COG1846	Transcriptional regulator
TD68_01350	COG0392	lysyltransferase activity
TD68_01350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TD68_01355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_01360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_01365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_01370	COG0384	phenazine biosynthesis protein PhzF
TD68_01375	COG0778	Nitroreductase
TD68_01385	COG1090	epimerase
TD68_01390	COG2137	regulation of response to DNA damage stimulus
TD68_01400	COG2814	Major facilitator Superfamily
TD68_01415	COG3103	Sh3 type 3 domain protein
TD68_01420	COG5658	integral membrane protein
TD68_01425	COG0596	Alpha beta hydrolase
TD68_01430	COG0463	Glycosyl transferase, family 2
TD68_01435	COG4485	Bacterial membrane protein, YfhO
TD68_01440	COG1988	membrane-bound metal-dependent
TD68_01445	COG1194	a g-specific adenine glycosylase
TD68_01455	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_01470	COG3557	Belongs to the UPF0374 family
TD68_01475	COG1132	(ABC) transporter
TD68_01480	COG4129	membrane
TD68_01485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TD68_01490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TD68_01495	COG0735	belongs to the Fur family
TD68_01605	COG1063	alcohol dehydrogenase
TD68_01610	COG5577	PFAM Coat F domain
TD68_01620	COG4326	sporulation control protein
TD68_01625	COG3340	Belongs to the peptidase S51 family
TD68_01630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TD68_01645	COG1116	anion transmembrane transporter activity
TD68_01650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD68_01655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD68_01665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TD68_01675	COG1476	TRANSCRIPTIONal
TD68_01685	COG3382	B3 4 domain protein
TD68_01690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TD68_01700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TD68_01705	COG0789	Transcriptional regulator
TD68_01710	COG1664	Polymer-forming cytoskeletal
TD68_01715	COG1664	Polymer-forming cytoskeletal
TD68_01720	COG2766	serine protein kinase
TD68_01725	COG2718	Belongs to the UPF0229 family
TD68_01730	COG1846	Transcriptional regulator
TD68_01735	COG1566	PFAM secretion protein HlyD family protein
TD68_01740	COG2814	Major facilitator Superfamily
TD68_01745	COG0655	NAD(P)H dehydrogenase (quinone) activity
TD68_01760	COG1725	Transcriptional regulator
TD68_01765	COG1131	(ABC) transporter
TD68_01770	COG1131	(ABC) transporter
TD68_01775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_01780	COG1278	Cold shock
TD68_01785	COG1464	Belongs to the NlpA lipoprotein family
TD68_01790	COG3706	GGDEF domain
TD68_01795	COG1823	symporter activity
TD68_01820	COG1525	nuclease
TD68_01820	COG0737	Belongs to the 5'-nucleotidase family
TD68_01820	COG4085	toxin activity
TD68_01825	COG3764	Sortase (surface protein transpeptidase)
TD68_01830	COG0564	pseudouridine synthase activity
TD68_01840	COG0517	IMP dehydrogenase activity
TD68_01845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TD68_01850	COG3153	acetyltransferase
TD68_01850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TD68_01860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_01865	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
TD68_01870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TD68_01875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TD68_01880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TD68_01885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TD68_01890	COG2203	Gaf domain
TD68_01890	COG4585	Histidine kinase
TD68_01895	COG2197	response regulator
TD68_01900	COG0431	NADPH-dependent FMN reductase
TD68_01915	COG1388	LysM domain
TD68_01915	COG0791	NLP P60 protein
TD68_01920	COG1959	2 iron, 2 sulfur cluster binding
TD68_01925	COG0668	transmembrane transport
TD68_01930	COG2719	SpoVR family
TD68_01935	COG1785	Belongs to the alkaline phosphatase family
TD68_01940	COG0791	NLP P60 protein
TD68_01940	COG1388	LysM domain
TD68_01945	COG0583	DNA-binding transcription factor activity
TD68_01950	COG0372	Belongs to the citrate synthase family
TD68_01955	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_01960	COG0531	amino acid
TD68_01965	COG0733	neurotransmitter:sodium symporter activity
TD68_01970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_01975	COG0456	acetyltransferase
TD68_01980	COG0833	amino acid
TD68_01985	COG4187	Peptidase family M20/M25/M40
TD68_01990	COG1012	belongs to the aldehyde dehydrogenase family
TD68_01995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_02010	COG1595	DNA-templated transcription, initiation
TD68_02015	COG0667	Aldo Keto reductase
TD68_02020	COG0204	Acyl-transferase
TD68_02025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_02030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_02035	COG1253	flavin adenine dinucleotide binding
TD68_02040	COG0789	Transcriptional regulator
TD68_02045	COG1253	flavin adenine dinucleotide binding
TD68_02050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD68_02055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD68_02060	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_02065	COG0668	transmembrane transport
TD68_02070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TD68_02075	COG0726	polysaccharide deacetylase
TD68_02080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_02085	COG1757	Na H antiporter
TD68_02090	COG0589	response to stress
TD68_02095	COG1132	(ABC) transporter
TD68_02100	COG1132	(ABC) transporter
TD68_02105	COG0702	epimerase
TD68_02120	COG0189	ligase activity
TD68_02125	COG0189	ligase activity
TD68_02135	COG4399	Belongs to the UPF0754 family
TD68_02145	COG4335	DNA alkylation repair
TD68_02150	COG0561	phosphatase activity
TD68_02155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD68_02165	COG0475	glutathione-regulated potassium exporter activity
TD68_02170	COG0490	domain, Protein
TD68_02180	COG1024	Enoyl-CoA hydratase
TD68_02190	COG4152	abc transporter atp-binding protein
TD68_02195	COG1668	transmembrane transport
TD68_02200	COG0420	3'-5' exonuclease activity
TD68_02205	COG4717	serine-type aminopeptidase activity
TD68_02210	COG3481	metal-dependent phosphohydrolase, HD sub domain
TD68_02220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD68_02255	COG4980	gas vesicle protein
TD68_02270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TD68_02275	COG0537	adenosine 5'-monophosphoramidase activity
TD68_02280	COG1131	(ABC) transporter
TD68_02285	COG4473	ABC transporter
TD68_02295	COG1473	amidohydrolase
TD68_02300	COG3069	C4-dicarboxylate transmembrane transporter activity
TD68_02305	COG2329	Antibiotic biosynthesis monooxygenase
TD68_02310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_02315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TD68_02330	COG1309	transcriptional regulator
TD68_02335	COG1511	domain protein
TD68_02340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_02350	COG1363	Peptidase, m42
TD68_02355	COG1301	dicarboxylic acid transport
TD68_02360	COG1234	tRNA 3'-trailer cleavage
TD68_02365	COG0095	Lipoate-protein ligase
TD68_02370	COG0702	epimerase
TD68_02375	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_02385	COG0501	Belongs to the peptidase M48B family
TD68_02390	COG1404	Belongs to the peptidase S8 family
TD68_02395	COG0456	acetyltransferase
TD68_02400	COG0604	alcohol dehydrogenase
TD68_02405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TD68_02410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_02415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_02420	COG0406	alpha-ribazole phosphatase activity
TD68_02425	COG0183	Belongs to the thiolase family
TD68_02430	COG1960	acyl-CoA dehydrogenase activity
TD68_02435	COG2084	Dehydrogenase
TD68_02440	COG1012	belongs to the aldehyde dehydrogenase family
TD68_02445	COG1024	Enoyl-CoA hydratase
TD68_02455	COG0840	transmembrane signaling receptor activity
TD68_02460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_02460	COG0723	plastoquinol--plastocyanin reductase activity
TD68_02465	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_02475	COG4903	ComK protein
TD68_02485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_02500	COG0398	Pfam SNARE associated Golgi protein
TD68_02505	COG0681	Belongs to the peptidase S26 family
TD68_02510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TD68_02515	COG1846	Transcriptional regulator
TD68_02520	COG3180	Ammonia monooxygenase
TD68_02530	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
TD68_02535	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TD68_02540	COG1074	ATP-dependent DNA helicase activity
TD68_02545	COG0420	3'-5' exonuclease activity
TD68_02550	COG0419	ATPase involved in DNA repair
TD68_02555	COG1403	HNH endonuclease
TD68_02590	COG2311	Membrane
TD68_02600	COG5337	Spore coat protein CotH
TD68_02605	COG0179	Fumarylacetoacetate (FAA) hydrolase
TD68_02615	COG1404	Belongs to the peptidase S8 family
TD68_02625	COG0367	asparagine synthase
TD68_02630	COG1562	ergosterol biosynthetic process
TD68_02635	COG0534	Mate efflux family protein
TD68_02640	COG2207	Transcriptional regulator
TD68_02640	COG1917	Cupin 2, conserved barrel domain protein
TD68_02645	COG0109	protoheme IX farnesyltransferase activity
TD68_02650	COG1609	Transcriptional regulator
TD68_02655	COG0673	inositol 2-dehydrogenase activity
TD68_02660	COG2318	DinB family
TD68_02670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_02675	COG1357	PFAM Pentapeptide repeats (8 copies)
TD68_02685	COG2267	carboxylic ester hydrolase activity
TD68_02690	COG0529	Catalyzes the synthesis of activated sulfate
TD68_02695	COG2046	Belongs to the sulfate adenylyltransferase family
TD68_02700	COG0175	sulfate reduction
TD68_02705	COG2045	Belongs to the ComB family
TD68_02710	COG1809	phosphosulfolactate synthase activity
TD68_02715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_02720	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_02725	COG2814	Major facilitator Superfamily
TD68_02735	COG2153	protein acetylation
TD68_02740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TD68_02740	COG0646	methionine synthase
TD68_02750	COG2996	Protein conserved in bacteria
TD68_02765	COG1307	EDD domain protein, DegV family
TD68_02770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_02785	COG0561	phosphatase activity
TD68_02790	COG1073	alpha beta
TD68_02795	COG2151	metal-sulfur cluster biosynthetic enzyme
TD68_02800	COG0277	FAD linked oxidase domain protein
TD68_02805	COG2271	Major facilitator Superfamily
TD68_02810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TD68_02825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD68_02830	COG0505	Belongs to the CarA family
TD68_02835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TD68_02840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TD68_02855	COG2267	carboxylic ester hydrolase activity
TD68_02865	COG1744	ABC transporter substrate-binding protein PnrA-like
TD68_02880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_02885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_02890	COG5504	Zn-dependent protease
TD68_02900	COG4608	Belongs to the ABC transporter superfamily
TD68_02910	COG0601	transmembrane transport
TD68_02915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_02925	COG0180	Tryptophanyl-tRNA synthetase
TD68_02930	COG4166	transmembrane transport
TD68_02935	COG0601	transmembrane transport
TD68_02940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_02945	COG0444	Belongs to the ABC transporter superfamily
TD68_02950	COG4608	Belongs to the ABC transporter superfamily
TD68_02955	COG2814	Major facilitator Superfamily
TD68_02965	COG0456	acetyltransferase
TD68_02970	COG1393	Belongs to the ArsC family
TD68_02975	COG0861	Integral membrane protein TerC family
TD68_02980	COG4862	establishment of competence for transformation
TD68_02985	COG4469	Competence protein
TD68_02990	COG1164	Oligoendopeptidase f
TD68_03010	COG0741	lytic transglycosylase activity
TD68_03015	COG4116	CYTH
TD68_03025	COG2357	RelA SpoT domain protein
TD68_03030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD68_03035	COG0564	pseudouridine synthase activity
TD68_03045	COG0569	domain protein
TD68_03045	COG0475	glutathione-regulated potassium exporter activity
TD68_03050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TD68_03055	COG0352	thiamine-phosphate diphosphorylase activity
TD68_03060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_03065	COG2104	thiamine diphosphate biosynthetic process
TD68_03070	COG2022	thiamine diphosphate biosynthetic process
TD68_03075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD68_03080	COG0351	phosphomethylpyrimidine kinase
TD68_03085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TD68_03135	COG0210	DNA helicase
TD68_03160	COG2153	protein acetylation
TD68_03170	COG2382	esterase
TD68_03175	COG0626	cystathionine gamma-synthase activity
TD68_03180	COG0626	cystathionine gamma-synthase activity
TD68_03185	COG5505	Protein of unknown function (DUF819)
TD68_03245	COG3209	COG3209 Rhs family protein
TD68_03250	COG1285	pathogenesis
TD68_03270	COG0726	polysaccharide deacetylase
TD68_03280	COG2205	protein histidine kinase activity
TD68_03290	COG3383	formate dehydrogenase (NAD+) activity
TD68_03295	COG2427	Protein of unknown function (DUF1641)
TD68_03305	COG1051	belongs to the nudix hydrolase family
TD68_03315	COG2124	cytochrome p450
TD68_03320	COG1819	glycosyl
TD68_03340	COG1587	Uroporphyrinogen-III synthase
TD68_03345	COG0390	transport system, permease component
TD68_03350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_03355	COG0697	spore germination
TD68_03360	COG4297	protein containing double-stranded beta helix domain
TD68_03370	COG1252	NADH dehydrogenase
TD68_03375	COG1904	glucuronate isomerase
TD68_03380	COG2211	Major facilitator Superfamily
TD68_03385	COG1609	Transcriptional regulator
TD68_03390	COG0246	Mannitol dehydrogenase
TD68_03395	COG2721	sulfolactate sulfo-lyase activity
TD68_03400	COG0730	response to heat
TD68_03405	COG2318	DinB family
TD68_03410	COG0457	Tetratricopeptide repeat
TD68_03420	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_03420	COG1388	LysM domain
TD68_03420	COG3409	Peptidoglycan-binding domain 1 protein
TD68_03430	COG4195	phage-related replication protein
TD68_03435	COG2856	Zn peptidase
TD68_03440	COG1396	sequence-specific DNA binding
TD68_03450	COG1522	sequence-specific DNA binding
TD68_03455	COG1484	DNA-dependent DNA replication
TD68_03470	COG1595	DNA-templated transcription, initiation
TD68_03475	COG5484	DNA packaging
TD68_03475	COG3728	DNA packaging
TD68_03480	COG1783	phage Terminase large subunit
TD68_03485	COG5518	Phage portal protein
TD68_03490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
TD68_03495	COG4653	Phage capsid family
TD68_03540	COG3953	SLT domain
TD68_03540	COG5412	phage tail tape measure protein
TD68_03545	COG1652	LysM domain
TD68_03550	COG4193	domain, Protein
TD68_03565	COG3628	GPW Gp25 family protein
TD68_03570	COG3299	homolog of phage Mu protein gp47
TD68_03575	COG3778	Protein conserved in bacteria
TD68_03615	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_03615	COG3409	Peptidoglycan-binding domain 1 protein
TD68_03630	COG0306	phosphate transporter
TD68_03635	COG1392	Phosphate transport regulator
TD68_03640	COG0531	amino acid
TD68_03645	COG0346	lactoylglutathione lyase activity
TD68_03650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TD68_03655	COG0463	Glycosyl transferase, family 2
TD68_03665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_03670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_03675	COG2362	D-Aminopeptidase
TD68_03680	COG0601	transmembrane transport
TD68_03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_03690	COG0444	Belongs to the ABC transporter superfamily
TD68_03695	COG4166	transmembrane transport
TD68_03700	COG1619	proteins homologs of microcin C7 resistance protein MccF
TD68_03705	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_03710	COG0791	NLP P60 protein
TD68_03715	COG4608	Belongs to the ABC transporter superfamily
TD68_03720	COG2706	6-phosphogluconolactonase activity
TD68_03725	COG1834	amidinotransferase
TD68_03730	COG1607	acyl-coa hydrolase
TD68_03735	COG2323	membrane
TD68_03740	COG1695	Transcriptional regulator
TD68_03755	COG2318	DinB family
TD68_03760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_03765	COG2076	Multidrug Resistance protein
TD68_03770	COG2076	Multidrug Resistance protein
TD68_03775	COG0788	formyltetrahydrofolate deformylase activity
TD68_03780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TD68_03785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TD68_03790	COG1764	response to oxidative stress
TD68_03795	COG1846	Transcriptional regulator
TD68_03800	COG1764	response to oxidative stress
TD68_03815	COG0463	Glycosyl transferase, family 2
TD68_03815	COG0457	Tetratricopeptide repeat
TD68_03825	COG0590	tRNA wobble adenosine to inosine editing
TD68_03835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TD68_03840	COG1404	Belongs to the peptidase S8 family
TD68_03845	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_03850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD68_03855	COG1122	ATPase activity
TD68_03860	COG4721	ABC-type cobalt transport system, permease component
TD68_03870	COG0745	RESPONSE REGULATOR receiver
TD68_03875	COG5002	protein histidine kinase activity
TD68_03875	COG3850	Histidine kinase
TD68_03880	COG3212	peptidase
TD68_03885	COG3212	peptidase
TD68_03890	COG2239	Acts as a magnesium transporter
TD68_03895	COG0789	Transcriptional regulator
TD68_03905	COG1846	Transcriptional regulator
TD68_03910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_03915	COG0726	polysaccharide deacetylase
TD68_03920	COG1408	metallophosphoesterase
TD68_03935	COG0463	Glycosyl transferase, family 2
TD68_03940	COG3285	dna ligase
TD68_03940	COG1793	dna ligase
TD68_03945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
TD68_03950	COG5001	Diguanylate cyclase
TD68_03950	COG3300	MHYT domain
TD68_03955	COG5001	Diguanylate cyclase
TD68_03955	COG3300	MHYT domain
TD68_03960	COG3300	MHYT domain
TD68_03960	COG5001	Diguanylate cyclase
TD68_03965	COG0586	Pfam SNARE associated Golgi protein
TD68_03970	COG0861	Integral membrane protein TerC family
TD68_03975	COG1191	sigma factor activity
TD68_03995	COG0501	Belongs to the peptidase M48B family
TD68_04000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD68_04005	COG2323	membrane
TD68_04010	COG3594	Acyltransferase
TD68_04015	COG5002	protein histidine kinase activity
TD68_04020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD68_04030	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
TD68_04035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TD68_04040	COG0436	Aminotransferase
TD68_04045	COG1850	ribulose-bisphosphate carboxylase activity
TD68_04055	COG0235	Class ii aldolase
TD68_04060	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
TD68_04065	COG3339	Conserved Protein
TD68_04080	COG3852	Histidine kinase
TD68_04085	COG1846	Transcriptional regulator
TD68_04090	COG1360	Flagellar Motor Protein
TD68_04095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD68_04100	COG0542	response to heat
TD68_04105	COG3949	Membrane
TD68_04120	COG0720	synthase
TD68_04125	COG0602	queuosine metabolic process
TD68_04130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TD68_04135	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_04145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_04150	COG4873	Protein conserved in bacteria
TD68_04160	COG3773	Cell wall hydrolase
TD68_04165	COG2244	polysaccharide biosynthetic process
TD68_04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_04175	COG2217	Heavy metal translocating P-type atpase
TD68_04185	COG0006	proline dipeptidase activity
TD68_04190	COG1609	Transcriptional regulator
TD68_04195	COG3711	transcriptional antiterminator
TD68_04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_04200	COG2190	(PTS) system
TD68_04200	COG1263	PTS System
TD68_04205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_04210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TD68_04220	COG1533	DNA photolyase activity
TD68_04225	COG0456	acetyltransferase
TD68_04230	COG0840	transmembrane signaling receptor activity
TD68_04235	COG2084	Dehydrogenase
TD68_04240	COG2340	Cysteine-rich secretory protein family
TD68_04245	COG0768	penicillin binding
TD68_04250	COG4191	Histidine kinase
TD68_04255	COG0436	Aminotransferase
TD68_04260	COG0835	chemotaxis
TD68_04260	COG0784	Response regulator, receiver
TD68_04270	COG2814	Major facilitator Superfamily
TD68_04275	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_04280	COG1408	metallophosphoesterase
TD68_04285	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_04290	COG2200	EAL domain
TD68_04295	COG3546	catalase activity
TD68_04300	COG4703	Protein of unknown function (DUF1797)
TD68_04305	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
TD68_04315	COG0517	IMP dehydrogenase activity
TD68_04320	COG0583	DNA-binding transcription factor activity
TD68_04325	COG0716	FMN binding
TD68_04335	COG0716	FMN binding
TD68_04340	COG2171	N-acyltransferase activity
TD68_04345	COG1473	amidohydrolase
TD68_04355	COG0668	transmembrane transport
TD68_04360	COG0450	alkyl hydroperoxide reductase
TD68_04365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_04380	COG0746	molybdenum cofactor guanylyltransferase activity
TD68_04385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD68_04390	COG0303	'Molybdopterin
TD68_04395	COG1763	Mo-molybdopterin cofactor biosynthetic process
TD68_04400	COG0314	molybdopterin synthase activity
TD68_04405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TD68_04410	COG1132	(ABC) transporter
TD68_04415	COG1132	(ABC) transporter
TD68_04425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TD68_04430	COG1136	(ABC) transporter
TD68_04435	COG0577	efflux transmembrane transporter activity
TD68_04440	COG1349	DNA-binding transcription factor activity
TD68_04445	COG1105	Belongs to the carbohydrate kinase PfkB family
TD68_04450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_04450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_04450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_04455	COG0681	Belongs to the peptidase S26 family
TD68_04465	COG0488	(ABC) transporter
TD68_04470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_04475	COG2309	aminopeptidase activity
TD68_04480	COG1077	Cell shape determining protein MreB Mrl
TD68_04485	COG2002	toxin-antitoxin pair type II binding
TD68_04490	COG3852	Histidine kinase
TD68_04495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
TD68_04495	COG2105	PFAM AIG2 family protein
TD68_04500	COG0569	domain protein
TD68_04505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TD68_04510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD68_04520	COG0561	phosphatase activity
TD68_04525	COG0242	peptide deformylase activity
TD68_04535	COG0497	DNA recombination
TD68_04540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_04545	COG0022	dehydrogenase e1 component
TD68_04550	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_04555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_04560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_04570	COG1982	Orn Lys Arg decarboxylase major
TD68_04575	COG4476	Belongs to the UPF0223 family
TD68_04580	COG4493	Belongs to the UPF0637 family
TD68_04590	COG0483	inositol monophosphate 1-phosphatase activity
TD68_04600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
TD68_04620	COG1595	DNA-templated transcription, initiation
TD68_04650	COG4896	Protein conserved in bacteria
TD68_04660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TD68_04665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TD68_04670	COG2066	Belongs to the glutaminase family
TD68_04675	COG4838	Belongs to the UPF0358 family
TD68_04680	COG0772	Belongs to the SEDS family
TD68_04685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TD68_04690	COG1612	heme a metabolic process
TD68_04700	COG2010	Cytochrome c
TD68_04700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TD68_04705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TD68_04710	COG1845	cytochrome c oxidase, subunit III
TD68_04715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
TD68_04720	COG3336	cytochrome c oxidase
TD68_04730	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
TD68_04735	COG2340	Cysteine-rich secretory protein family
TD68_04755	COG3679	Belongs to the UPF0342 family
TD68_04760	COG4471	UPF0298 protein
TD68_04765	COG0742	ribosomal rna small subunit methyltransferase
TD68_04770	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TD68_04775	COG3314	Sporulation integral membrane protein YlbJ
TD68_04780	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD68_04785	COG3480	Lon protease (S16) C-terminal proteolytic domain
TD68_04790	COG1323	Belongs to the UPF0348 family
TD68_04795	COG1399	metal-binding, possibly nucleic acid-binding protein
TD68_04800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TD68_04815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_04820	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
TD68_04825	COG2001	Belongs to the MraZ family
TD68_04830	COG0275	rRNA processing
TD68_04835	COG4839	cell division protein FtsL
TD68_04845	COG0768	penicillin binding
TD68_04850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TD68_04855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TD68_04860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TD68_04865	COG0772	Belongs to the SEDS family
TD68_04870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_04875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TD68_04880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TD68_04885	COG3879	Bacterial protein of unknown function (DUF881)
TD68_04890	COG3879	Bacterial protein of unknown function (DUF881)
TD68_04895	COG3856	small basic protein
TD68_04900	COG0849	cell division
TD68_04905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TD68_04910	COG4412	M6 family metalloprotease domain protein
TD68_04910	COG1404	Belongs to the peptidase S8 family
TD68_04920	COG1191	sigma factor activity
TD68_04925	COG1191	sigma factor activity
TD68_04930	COG1119	ATPase activity
TD68_04935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_04940	COG1873	PFAM PRC-barrel domain
TD68_04950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TD68_04955	COG1799	cell septum assembly
TD68_04960	COG0762	integral membrane protein
TD68_04965	COG2302	S4 RNA-binding domain
TD68_04970	COG3599	regulation of cell shape
TD68_04975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TD68_04980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_04985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TD68_04990	COG0564	pseudouridine synthase activity
TD68_05000	COG2233	PERMEase
TD68_05005	COG0540	Belongs to the ATCase OTCase family
TD68_05010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TD68_05015	COG0505	Belongs to the CarA family
TD68_05020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TD68_05025	COG0543	2 iron, 2 sulfur cluster binding
TD68_05030	COG0167	dihydroorotate dehydrogenase activity
TD68_05035	COG0284	orotidine-5'-phosphate decarboxylase activity
TD68_05040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TD68_05045	COG0175	sulfate reduction
TD68_05050	COG0306	phosphate transporter
TD68_05055	COG2046	Belongs to the sulfate adenylyltransferase family
TD68_05060	COG0529	Catalyzes the synthesis of activated sulfate
TD68_05065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TD68_05070	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
TD68_05075	COG1648	precorrin-2 dehydrogenase activity
TD68_05085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TD68_05090	COG1561	YicC-like family, N-terminal region
TD68_05095	COG2052	Domain of unknown function (DUF370)
TD68_05100	COG0194	GDP metabolic process
TD68_05105	COG1758	RNA polymerase activity
TD68_05110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD68_05115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TD68_05120	COG0242	peptide deformylase activity
TD68_05125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TD68_05130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TD68_05130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TD68_05140	COG0631	protein serine/threonine phosphatase activity
TD68_05145	COG2815	serine threonine protein kinase
TD68_05145	COG0515	serine threonine protein kinase
TD68_05150	COG1162	GTPase activity
TD68_05155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TD68_05160	COG1564	THIamine pyrophosphokinase
TD68_05170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TD68_05175	COG1302	Protein conserved in bacteria
TD68_05180	COG1461	Dihydroxyacetone kinase
TD68_05185	COG1760	l-serine dehydratase
TD68_05190	COG1760	l-serine dehydratase
TD68_05195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TD68_05200	COG1349	DNA-binding transcription factor activity
TD68_05200	COG2050	protein possibly involved in aromatic compounds catabolism
TD68_05210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_05215	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_05220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_05225	COG0571	ribonuclease III activity
TD68_05230	COG1196	nuclear chromosome segregation
TD68_05235	COG0552	protein localization to endoplasmic reticulum
TD68_05240	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
TD68_05245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TD68_05250	COG0228	four-way junction DNA binding
TD68_05255	COG1837	Belongs to the UPF0109 family
TD68_05265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TD68_05270	COG0336	Belongs to the RNA methyltransferase TrmD family
TD68_05280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TD68_05285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TD68_05295	COG2257	FlhB HrpN YscU SpaS Family
TD68_05305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TD68_05310	COG0758	DNA mediated transformation
TD68_05315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD68_05320	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TD68_05325	COG4974	Belongs to the 'phage' integrase family
TD68_05330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TD68_05335	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TD68_05345	COG1815	bacterial-type flagellum-dependent cell motility
TD68_05350	COG1558	bacterial-type flagellum-dependent cell motility
TD68_05355	COG1677	Flagellar hook-basal body complex protein FliE
TD68_05360	COG1766	The M ring may be actively involved in energy transduction
TD68_05365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_05370	COG1317	bacterial-type flagellum organization
TD68_05375	COG1157	protein secretion by the type III secretion system
TD68_05380	COG2882	bacterial-type flagellum organization
TD68_05385	COG3334	PFAM MgtE intracellular
TD68_05390	COG3144	bacterial-type flagellum assembly
TD68_05395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TD68_05400	COG4786	Flagellar basal body rod
TD68_05405	COG1582	Flagellar protein (FlbD)
TD68_05410	COG1580	Controls the rotational direction of flagella during chemotaxis
TD68_05415	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_05420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_05420	COG1776	CheC inhibitor of MCP methylation
TD68_05425	COG2201	protein-glutamate methylesterase activity
TD68_05430	COG3190	flagellar
TD68_05435	COG1338	Plays a role in the flagellum-specific transport system
TD68_05440	COG1987	bacterial-type flagellum assembly
TD68_05445	COG1684	flagellar biosynthetic protein fliR
TD68_05450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD68_05455	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD68_05460	COG1419	protein localization to endoplasmic reticulum
TD68_05465	COG0455	bacterial-type flagellum organization
TD68_05470	COG2201	protein-glutamate methylesterase activity
TD68_05475	COG0643	Histidine kinase
TD68_05475	COG2198	Histidine kinase
TD68_05480	COG0835	chemotaxis
TD68_05485	COG1776	CheC inhibitor of MCP methylation
TD68_05490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TD68_05495	COG1191	sigma factor activity
TD68_05510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TD68_05515	COG0528	UMP kinase activity
TD68_05520	COG0233	cytoplasmic translational termination
TD68_05525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TD68_05530	COG4589	Belongs to the CDS family
TD68_05535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TD68_05540	COG0750	zinc metalloprotease
TD68_05545	COG0442	prolyl-tRNA aminoacylation
TD68_05550	COG2176	DNA-directed DNA polymerase activity
TD68_05555	COG0779	Required for maturation of 30S ribosomal subunits
TD68_05560	COG0195	Participates in both transcription termination and antitermination
TD68_05565	COG2740	Nucleic-acid-binding protein implicated in transcription termination
TD68_05570	COG1358	cellular component organization or biogenesis
TD68_05575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TD68_05580	COG1550	Protein conserved in bacteria
TD68_05585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TD68_05590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TD68_05595	COG0196	riboflavin kinase activity
TD68_05605	COG1185	polyribonucleotide nucleotidyltransferase activity
TD68_05610	COG0726	polysaccharide deacetylase
TD68_05615	COG0612	Peptidase, M16
TD68_05620	COG1873	PFAM PRC-barrel domain
TD68_05625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD68_05630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD68_05635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TD68_05640	COG0527	aspartate kinase activity
TD68_05650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD68_05655	COG0740	serine-type endopeptidase activity
TD68_05665	COG1674	ftsk spoiiie
TD68_05665	COG4980	gas vesicle protein
TD68_05670	COG2188	Transcriptional regulator
TD68_05675	COG2814	Major facilitator Superfamily
TD68_05680	COG0612	Peptidase, M16
TD68_05685	COG0612	Peptidase, M16
TD68_05690	COG0300	oxidoreductase activity
TD68_05705	COG1426	Protein conserved in bacteria
TD68_05710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TD68_05715	COG1058	Belongs to the CinA family
TD68_05715	COG1546	Belongs to the CinA family
TD68_05720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TD68_05725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_05735	COG1692	metallophosphoesterase
TD68_05740	COG2359	stage V sporulation protein S
TD68_05745	COG1063	alcohol dehydrogenase
TD68_05750	COG0156	8-amino-7-oxononanoate synthase activity
TD68_05765	COG4550	Control of competence regulator ComK, YlbF/YmcA
TD68_05775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TD68_05780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TD68_05795	COG3226	Transcriptional regulator
TD68_05800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_05805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_05810	COG3321	synthase
TD68_05815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_05815	COG2070	2-Nitropropane dioxygenase
TD68_05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_05825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_05830	COG3425	synthase
TD68_05835	COG1024	Enoyl-CoA hydratase
TD68_05840	COG1024	Enoyl-CoA hydratase
TD68_05845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_05845	COG0300	oxidoreductase activity
TD68_05845	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_05845	COG3321	synthase
TD68_05845	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_05850	COG4221	oxidoreductase activity
TD68_05850	COG3321	synthase
TD68_05850	COG0300	oxidoreductase activity
TD68_05850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_05855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_05855	COG3321	synthase
TD68_05855	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_05855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_05855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_05860	COG4221	oxidoreductase activity
TD68_05860	COG3321	synthase
TD68_05860	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_05860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_05865	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TD68_05865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_05865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TD68_05865	COG3321	synthase
TD68_05870	COG2124	cytochrome p450
TD68_05880	COG1404	Belongs to the peptidase S8 family
TD68_05890	COG4195	phage-related replication protein
TD68_05895	COG1764	response to oxidative stress
TD68_05905	COG2076	Multidrug Resistance protein
TD68_05925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TD68_05945	COG1780	Probably involved in ribonucleotide reductase function
TD68_05950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD68_05955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD68_05960	COG4112	unkown
TD68_05965	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_05970	COG0464	growth
TD68_05975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TD68_05980	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
TD68_05985	COG0789	Transcriptional regulator
TD68_05990	COG0174	glutamine synthetase
TD68_06005	COG0456	acetyltransferase
TD68_06010	COG1525	nuclease
TD68_06015	COG4282	regulation of fungal-type cell wall biogenesis
TD68_06020	COG5444	nuclease activity
TD68_06035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_06055	COG0346	lactoylglutathione lyase activity
TD68_06075	COG2273	Hydrolase Family 16
TD68_06095	COG3391	amine dehydrogenase activity
TD68_06120	COG1011	Hydrolase
TD68_06125	COG0667	Aldo Keto reductase
TD68_06145	COG2318	DinB family
TD68_06150	COG2367	Beta-lactamase
TD68_06155	COG1388	LysM domain
TD68_06155	COG4641	Protein conserved in bacteria
TD68_06160	COG1388	LysM domain
TD68_06165	COG3858	chitin binding
TD68_06170	COG2720	vancomycin resistance protein
TD68_06175	COG5553	Cysteine dioxygenase type I
TD68_06185	COG3409	Peptidoglycan-binding domain 1 protein
TD68_06205	COG0456	acetyltransferase
TD68_06210	COG0789	Transcriptional regulator
TD68_06210	COG4978	Transcriptional regulator
TD68_06215	COG2030	dehydratase
TD68_06230	COG2135	peptidase activity
TD68_06245	COG0457	Tetratricopeptide repeat
TD68_06260	COG1131	(ABC) transporter
TD68_06305	COG4195	phage-related replication protein
TD68_06310	COG3619	membrane
TD68_06330	COG4195	phage-related replication protein
TD68_06355	COG5577	PFAM Coat F domain
TD68_06365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TD68_06370	COG1388	LysM domain
TD68_06375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TD68_06380	COG4224	UPF0291 protein
TD68_06385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TD68_06395	COG3763	UPF0154 protein
TD68_06405	COG0785	Cytochrome C biogenesis protein
TD68_06410	COG2201	protein-glutamate methylesterase activity
TD68_06415	COG4846	Membrane protein involved in cytochrome C biogenesis
TD68_06425	COG0071	Belongs to the small heat shock protein (HSP20) family
TD68_06440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TD68_06445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_06460	COG0824	Thioesterase
TD68_06470	COG4841	protein insertion into membrane
TD68_06475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TD68_06480	COG1832	CoA-binding protein
TD68_06485	COG0187	DNA topoisomerase II activity
TD68_06490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD68_06500	COG1115	amino acid carrier protein
TD68_06510	COG0745	RESPONSE REGULATOR receiver
TD68_06520	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_06525	COG2246	polysaccharide biosynthetic process
TD68_06535	COG0586	Pfam SNARE associated Golgi protein
TD68_06540	COG2404	hydrolase activity, acting on ester bonds
TD68_06545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TD68_06550	COG1024	Enoyl-CoA hydratase
TD68_06555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TD68_06560	COG0511	ligase activity, forming carbon-carbon bonds
TD68_06565	COG0439	Biotin carboxylase
TD68_06570	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_06575	COG1960	acyl-CoA dehydrogenase activity
TD68_06580	COG1649	PFAM Uncharacterised BCR, COG1649
TD68_06590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TD68_06590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_06595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_06600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_06605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_06610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_06615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TD68_06615	COG1017	nitric oxide dioxygenase activity
TD68_06620	COG2027	D-alanyl-D-alanine carboxypeptidase
TD68_06625	COG2017	converts alpha-aldose to the beta-anomer
TD68_06635	COG2207	Transcriptional regulator
TD68_06635	COG3708	Transcriptional regulator
TD68_06640	COG0457	Tetratricopeptide repeat
TD68_06650	COG3409	Peptidoglycan-binding domain 1 protein
TD68_06650	COG1388	LysM domain
TD68_06650	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_06660	COG0582	viral genome integration into host DNA
TD68_06665	COG0166	Belongs to the GPI family
TD68_06670	COG0405	Gamma-glutamyltransferase
TD68_06680	COG0604	alcohol dehydrogenase
TD68_06685	COG0493	'glutamate synthase
TD68_06690	COG0070	glutamate synthase
TD68_06690	COG0069	glutamate synthase activity
TD68_06690	COG0067	glutamate synthase
TD68_06695	COG0583	DNA-binding transcription factor activity
TD68_06700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TD68_06755	COG3331	DNA recombination
TD68_06765	COG0252	asparaginase activity
TD68_06770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TD68_06775	COG0251	oxidation-reduction process
TD68_06810	COG0756	dUTP diphosphatase activity
TD68_06855	COG0693	protein deglycase activity
TD68_06990	COG3655	Transcriptional regulator
TD68_07005	COG0582	viral genome integration into host DNA
TD68_07085	COG3655	Transcriptional regulator
TD68_07130	COG1395	domain, Protein
TD68_07150	COG0776	regulation of translation
TD68_07280	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_07310	COG1196	nuclear chromosome segregation
TD68_07310	COG0741	lytic transglycosylase activity
TD68_07310	COG0739	heme binding
TD68_07315	COG1196	nuclear chromosome segregation
TD68_07315	COG0741	lytic transglycosylase activity
TD68_07315	COG0739	heme binding
TD68_07325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_07355	COG4282	regulation of fungal-type cell wall biogenesis
TD68_07360	COG0693	protein deglycase activity
TD68_07365	COG0300	oxidoreductase activity
TD68_07370	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
TD68_07375	COG2318	DinB family
TD68_07380	COG2814	Major facilitator Superfamily
TD68_07385	COG1070	Carbohydrate kinase
TD68_07390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TD68_07395	COG0243	molybdopterin cofactor binding
TD68_07410	COG1309	transcriptional regulator
TD68_07415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_07420	COG0662	Cupin 2, conserved barrel domain protein
TD68_07420	COG2207	Transcriptional regulator
TD68_07425	COG1309	transcriptional regulator
TD68_07430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_07435	COG3708	Transcriptional regulator
TD68_07440	COG2378	regulation of single-species biofilm formation
TD68_07450	COG0640	Transcriptional regulator
TD68_07455	COG0741	lytic transglycosylase activity
TD68_07460	COG2322	membrane
TD68_07475	COG3239	Fatty acid desaturase
TD68_07480	COG4585	Histidine kinase
TD68_07485	COG2197	response regulator
TD68_07495	COG1388	LysM domain
TD68_07495	COG3584	3D domain protein
TD68_07500	COG0514	ATP-dependent DNA helicase (RecQ)
TD68_07505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD68_07510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_07525	COG1012	belongs to the aldehyde dehydrogenase family
TD68_07530	COG1657	PFAM Prenyltransferase squalene oxidase
TD68_07535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD68_07540	COG0733	neurotransmitter:sodium symporter activity
TD68_07545	COG0385	Bile acid
TD68_07550	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_07555	COG0567	Dehydrogenase, E1 component
TD68_07560	COG4548	von Willebrand factor, type A
TD68_07565	COG0714	Associated with various cellular activities
TD68_07570	COG2032	superoxide dismutase activity
TD68_07575	COG1388	LysM domain
TD68_07575	COG0791	NLP P60 protein
TD68_07580	COG1819	glycosyl
TD68_07585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TD68_07590	COG0534	Mate efflux family protein
TD68_07595	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_07600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_07605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_07615	COG2962	Rard protein
TD68_07635	COG2318	DinB family
TD68_07645	COG1942	4-Oxalocrotonate Tautomerase
TD68_07650	COG1733	regulation of RNA biosynthetic process
TD68_07655	COG0778	Nitroreductase
TD68_07660	COG0400	carboxylic ester hydrolase activity
TD68_07665	COG0346	lactoylglutathione lyase activity
TD68_07675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_07680	COG3409	Peptidoglycan-binding domain 1 protein
TD68_07680	COG0793	Belongs to the peptidase S41A family
TD68_07685	COG2226	methyltransferase
TD68_07695	COG1876	peptidase activity
TD68_07700	COG0813	purine-nucleoside phosphorylase activity
TD68_07710	COG0671	phosphoesterase, PA-phosphatase related
TD68_07735	COG1509	lysine 2,3-aminomutase activity
TD68_07740	COG0456	acetyltransferase
TD68_07745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_07750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TD68_07755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
TD68_07760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_07770	COG0456	acetyltransferase
TD68_07775	COG0463	Glycosyl transferase, family 2
TD68_07790	COG4641	Protein conserved in bacteria
TD68_07795	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
TD68_07800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD68_07805	COG0366	Alpha amylase catalytic
TD68_07810	COG3397	chitin binding
TD68_07820	COG3655	Transcriptional regulator
TD68_07825	COG3739	integral membrane protein
TD68_07830	COG2207	Transcriptional regulator
TD68_07830	COG3708	Transcriptional regulator
TD68_07850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TD68_07855	COG1846	Transcriptional regulator
TD68_07860	COG0534	Mate efflux family protein
TD68_07870	COG4698	Protein conserved in bacteria
TD68_07875	COG2755	lipolytic protein G-D-S-L family
TD68_07880	COG1999	signal sequence binding
TD68_07890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TD68_07895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TD68_07900	COG1272	protein, Hemolysin III
TD68_07905	COG0204	Acyl-transferase
TD68_07910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TD68_07920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TD68_07930	COG2521	methyltransferase
TD68_07930	COG2136	Putative SAM-dependent methyltransferase
TD68_07945	COG1413	lyase activity
TD68_07950	COG1418	mRNA catabolic process
TD68_07955	COG0386	Belongs to the glutathione peroxidase family
TD68_07960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TD68_07965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_07970	COG1278	Cold shock
TD68_07990	COG0328	RNA-DNA hybrid ribonuclease activity
TD68_07995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
TD68_08000	COG0328	RNA-DNA hybrid ribonuclease activity
TD68_08010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_08020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD68_08025	COG1755	Isoprenylcysteine carboxyl methyltransferase
TD68_08030	COG3424	synthase
TD68_08035	COG2233	PERMEase
TD68_08040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TD68_08045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TD68_08055	COG0800	Aldolase
TD68_08060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_08065	COG1609	Transcriptional regulator
TD68_08070	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
TD68_08075	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_08080	COG1199	ATP-dependent helicase activity
TD68_08090	COG0116	Belongs to the methyltransferase superfamily
TD68_08105	COG3359	exonuclease
TD68_08110	COG1205	dead DEAH box helicase
TD68_08110	COG1111	helicase
TD68_08115	COG2190	(PTS) system
TD68_08120	COG0071	Belongs to the small heat shock protein (HSP20) family
TD68_08155	COG3331	DNA recombination
TD68_08160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_08160	COG4499	WXG100 protein secretion system (Wss), protein YukC
TD68_08170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TD68_08175	COG3935	DnaD domain protein
TD68_08180	COG0017	Asparaginyl-tRNA synthetase
TD68_08185	COG0436	Aminotransferase
TD68_08190	COG5353	protein conserved in bacteria
TD68_08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TD68_08195	COG1199	ATP-dependent helicase activity
TD68_08200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TD68_08205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TD68_08210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TD68_08220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TD68_08220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TD68_08225	COG0617	tRNA 3'-terminal CCA addition
TD68_08230	COG0438	transferase activity, transferring glycosyl groups
TD68_08235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_08250	COG1694	Mazg nucleotide pyrophosphohydrolase
TD68_08255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_08260	COG2140	Oxalate decarboxylase
TD68_08270	COG4347	Protein of unknown function (DUF1405)
TD68_08275	COG2010	Cytochrome c
TD68_08275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TD68_08280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TD68_08285	COG0723	plastoquinol--plastocyanin reductase activity
TD68_08295	COG5582	Belongs to the UPF0302 family
TD68_08300	COG0457	Tetratricopeptide repeat
TD68_08305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TD68_08310	COG0287	Prephenate dehydrogenase
TD68_08315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TD68_08320	COG0159	tryptophan synthase activity
TD68_08340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TD68_08345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TD68_08350	COG4401	Chorismate mutase type I
TD68_08355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TD68_08360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TD68_08365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TD68_08370	COG0105	UTP biosynthetic process
TD68_08375	COG0142	geranyltranstransferase activity
TD68_08385	COG0142	geranyltranstransferase activity
TD68_08395	COG0302	gtp cyclohydrolase
TD68_08400	COG0776	regulation of translation
TD68_08405	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD68_08420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TD68_08425	COG1160	GTP binding
TD68_08445	COG1304	FMN binding
TD68_08450	COG0539	negative regulation of cytoplasmic translation
TD68_08455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TD68_08460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
TD68_08465	COG2959	enzyme of heme biosynthesis
TD68_08470	COG3409	Peptidoglycan-binding domain 1 protein
TD68_08470	COG3773	Cell wall hydrolase
TD68_08475	COG2339	peptidase activity
TD68_08480	COG0492	ferredoxin-NADP+ reductase activity
TD68_08485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_08490	COG4862	establishment of competence for transformation
TD68_08495	COG1408	metallophosphoesterase
TD68_08505	COG1388	LysM domain
TD68_08510	COG1266	CAAX protease self-immunity
TD68_08515	COG0514	ATP-dependent DNA helicase (RecQ)
TD68_08520	COG4955	Helix-turn-helix domain
TD68_08525	COG1141	Ferredoxin
TD68_08530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
TD68_08535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TD68_08540	COG0710	3-dehydroquinate dehydratase activity
TD68_08550	COG1595	DNA-templated transcription, initiation
TD68_08555	COG5002	protein histidine kinase activity
TD68_08560	COG0745	RESPONSE REGULATOR receiver
TD68_08565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD68_08570	COG1333	cytochrome c biogenesis protein
TD68_08575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_08580	COG1187	pseudouridine synthase activity
TD68_08585	COG0700	Nucleoside recognition
TD68_08590	COG2715	membrane protein required for spore maturation
TD68_08595	COG1686	Belongs to the peptidase S11 family
TD68_08605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TD68_08610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TD68_08615	COG1547	Domain of unknown function (DUF309)
TD68_08620	COG0456	acetyltransferase
TD68_08625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TD68_08630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TD68_08630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TD68_08635	COG0307	riboflavin synthase, alpha
TD68_08640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD68_08640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD68_08655	COG0681	Belongs to the peptidase S26 family
TD68_08660	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
TD68_08665	COG1278	Cold shock
TD68_08670	COG0823	Involved in the tonB-independent uptake of proteins
TD68_08680	COG3420	alginic acid biosynthetic process
TD68_08690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD68_08700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD68_08735	COG0322	excinuclease ABC activity
TD68_08740	COG3584	3D domain protein
TD68_08790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TD68_08820	COG1428	Deoxynucleoside kinase
TD68_08830	COG1435	thymidine kinase activity
TD68_08845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TD68_09045	COG0457	Tetratricopeptide repeat
TD68_09070	COG4086	secreted protein
TD68_09075	COG0019	diaminopimelate decarboxylase activity
TD68_09080	COG0697	spore germination
TD68_09095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_09115	COG1191	sigma factor activity
TD68_09120	COG2172	sigma factor antagonist activity
TD68_09125	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_09130	COG1686	Belongs to the peptidase S11 family
TD68_09135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TD68_09140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TD68_09145	COG4974	Belongs to the 'phage' integrase family
TD68_09155	COG0735	belongs to the Fur family
TD68_09160	COG1300	Membrane
TD68_09170	COG0281	malic enzyme
TD68_09175	COG1757	Na H antiporter
TD68_09180	COG1027	Aspartate ammonia-lyase
TD68_09185	COG0252	asparaginase activity
TD68_09190	COG1396	sequence-specific DNA binding
TD68_09195	COG1379	DNA repair
TD68_09200	COG0494	nUDIX hydrolase
TD68_09210	COG0667	Aldo Keto reductase
TD68_09220	COG1073	alpha beta
TD68_09230	COG4918	Iron-sulphur cluster biosynthesis
TD68_09235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TD68_09235	COG0456	acetyltransferase
TD68_09245	COG0456	acetyltransferase
TD68_09255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_09265	COG0628	permease
TD68_09270	COG2211	Major facilitator Superfamily
TD68_09275	COG0346	lactoylglutathione lyase activity
TD68_09280	COG1072	(Pantothenic acid kinase))
TD68_09285	COG3048	D-serine ammonia-lyase activity
TD68_09290	COG0300	oxidoreductase activity
TD68_09295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_09300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_09305	COG4187	Peptidase family M20/M25/M40
TD68_09310	COG1902	pentaerythritol trinitrate reductase activity
TD68_09315	COG0596	Alpha beta hydrolase
TD68_09325	COG1234	tRNA 3'-trailer cleavage
TD68_09330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TD68_09335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TD68_09340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_09350	COG0706	membrane insertase activity
TD68_09355	COG3361	conserved protein (COG2071)
TD68_09360	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD68_09365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TD68_09370	COG0346	lactoylglutathione lyase activity
TD68_09375	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_09380	COG4129	membrane
TD68_09385	COG1126	abc transporter atp-binding protein
TD68_09390	COG0765	amino acid transport
TD68_09395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_09405	COG1597	lipid kinase activity
TD68_09415	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_09420	COG0022	dehydrogenase e1 component
TD68_09425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_09430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_09435	COG3426	butyrate kinase activity
TD68_09440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_09445	COG0280	phosphate acetyltransferase
TD68_09450	COG3829	transcription factor binding
TD68_09450	COG3290	protein histidine kinase activity
TD68_09460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TD68_09465	COG2079	MmgE PrpD family protein
TD68_09475	COG1960	acyl-CoA dehydrogenase activity
TD68_09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD68_09485	COG0183	Belongs to the thiolase family
TD68_09490	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_09495	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_09505	COG1902	pentaerythritol trinitrate reductase activity
TD68_09515	COG0745	RESPONSE REGULATOR receiver
TD68_09520	COG0750	zinc metalloprotease
TD68_09525	COG0497	DNA recombination
TD68_09530	COG1438	arginine binding
TD68_09535	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
TD68_09540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TD68_09545	COG0142	geranyltranstransferase activity
TD68_09550	COG1722	exodeoxyribonuclease VII activity
TD68_09555	COG1570	exodeoxyribonuclease VII activity
TD68_09560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TD68_09565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TD68_09570	COG1302	Protein conserved in bacteria
TD68_09575	COG0439	Biotin carboxylase
TD68_09580	COG0511	ligase activity, forming carbon-carbon bonds
TD68_09620	COG3854	ATPases associated with a variety of cellular activities
TD68_09630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TD68_09635	COG0006	proline dipeptidase activity
TD68_09640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TD68_09650	COG3872	metal-dependent enzyme
TD68_09660	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD68_09665	COG1321	iron dependent repressor
TD68_09670	COG0095	Lipoate-protein ligase
TD68_09675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_09680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TD68_09685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TD68_09690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TD68_09695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD68_09710	COG1396	sequence-specific DNA binding
TD68_09720	COG0681	Belongs to the peptidase S26 family
TD68_09745	COG4940	Competence protein ComGF
TD68_09755	COG4970	Tfp pilus assembly protein FimT
TD68_09760	COG4537	Required for transformation and DNA binding
TD68_09765	COG1459	type II secretion system
TD68_09770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TD68_09775	COG0598	Magnesium transport protein CorA
TD68_09780	COG1253	flavin adenine dinucleotide binding
TD68_09785	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_09795	COG1393	Belongs to the ArsC family
TD68_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_09815	COG0011	TIGRFAM Protein of
TD68_09825	COG2866	Carboxypeptidase
TD68_09830	COG1368	sulfuric ester hydrolase activity
TD68_09835	COG1940	carbohydrate kinase activity
TD68_09840	COG4483	Protein conserved in bacteria
TD68_09845	COG0705	Rhomboid family
TD68_09845	COG0457	Tetratricopeptide repeat
TD68_09850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TD68_09855	COG0438	transferase activity, transferring glycosyl groups
TD68_09870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TD68_09875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_09880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_09885	COG0581	inorganic phosphate transmembrane transporter activity
TD68_09890	COG0573	inorganic phosphate transmembrane transporter activity
TD68_09895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TD68_09905	COG0477	Major facilitator Superfamily
TD68_09910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD68_09915	COG2839	Protein conserved in bacteria
TD68_09920	COG5521	maltodextrose utilization protein MalA
TD68_09925	COG1388	LysM domain
TD68_09935	COG4709	membrane
TD68_09940	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
TD68_09945	COG0735	belongs to the Fur family
TD68_09950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_09960	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TD68_09965	COG0513	Belongs to the DEAD box helicase family
TD68_09975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TD68_09980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TD68_09985	COG2384	SAM-dependent methyltransferase
TD68_09990	COG2010	Cytochrome c
TD68_09995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TD68_10000	COG0358	DNA primase activity
TD68_10005	COG1671	Belongs to the UPF0178 family
TD68_10010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
TD68_10015	COG0517	IMP dehydrogenase activity
TD68_10020	COG0751	glycine-tRNA ligase activity
TD68_10025	COG0752	glycyl-tRNA synthetase alpha subunit
TD68_10030	COG1381	Involved in DNA repair and RecF pathway recombination
TD68_10035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TD68_10040	COG0295	cytidine deaminase activity
TD68_10045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TD68_10055	COG1480	7TM receptor with intracellular HD hydrolase
TD68_10060	COG1702	phosphate starvation-inducible protein PhoH
TD68_10065	COG0561	phosphatase activity
TD68_10080	COG4864	UPF0365 protein
TD68_10085	COG1030	water channel activity
TD68_10090	COG1610	YqeY-like protein
TD68_10095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TD68_10100	COG1283	sodium-dependent phosphate transmembrane transporter activity
TD68_10105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TD68_10110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TD68_10130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TD68_10135	COG1420	regulation of RNA biosynthetic process
TD68_10140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD68_10145	COG0481	GTPase activity
TD68_10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_10170	COG1466	dna polymerase III delta subunit
TD68_10180	COG2333	competence protein COMEC
TD68_10180	COG0658	competence protein
TD68_10185	COG2131	deaminase
TD68_10190	COG1596	polysaccharide export
TD68_10190	COG1555	photosystem II stabilization
TD68_10195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_10200	COG2226	methyltransferase
TD68_10205	COG0799	negative regulation of ribosome biogenesis
TD68_10210	COG1713	HD superfamily hydrolase involved in NAD metabolism
TD68_10215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TD68_10220	COG1534	Rna-binding protein
TD68_10225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TD68_10230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TD68_10235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TD68_10245	COG2755	lipolytic protein G-D-S-L family
TD68_10250	COG0726	polysaccharide deacetylase
TD68_10260	COG0398	Pfam SNARE associated Golgi protein
TD68_10270	COG5444	nuclease activity
TD68_10285	COG2732	(Barnase) inhibitor
TD68_10305	COG1725	Transcriptional regulator
TD68_10315	COG0583	DNA-binding transcription factor activity
TD68_10325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_10345	COG0583	DNA-binding transcription factor activity
TD68_10350	COG2814	Major facilitator Superfamily
TD68_10355	COG2176	DNA-directed DNA polymerase activity
TD68_10360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_10360	COG2124	cytochrome p450
TD68_10365	COG1309	transcriptional regulator
TD68_10370	COG2226	methyltransferase
TD68_10375	COG2116	formate transmembrane transporter activity
TD68_10380	COG5609	conserved protein (DUF2294)
TD68_10385	COG3383	formate dehydrogenase (NAD+) activity
TD68_10390	COG2427	Protein of unknown function (DUF1641)
TD68_10400	COG0626	cystathionine gamma-synthase activity
TD68_10405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_10410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TD68_10415	COG2226	methyltransferase
TD68_10430	COG0768	penicillin binding
TD68_10435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TD68_10440	COG0572	uridine kinase
TD68_10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TD68_10465	COG3906	Belongs to the UPF0473 family
TD68_10470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TD68_10475	COG4472	Bacterial protein of unknown function (DUF965)
TD68_10480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TD68_10485	COG0628	permease
TD68_10490	COG1126	abc transporter atp-binding protein
TD68_10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_10500	COG0765	amino acid transport
TD68_10505	COG0765	amino acid transport
TD68_10515	COG3881	PFAM PRC-barrel domain
TD68_10520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TD68_10525	COG0457	Tetratricopeptide repeat
TD68_10530	COG0482	sulfurtransferase activity
TD68_10535	COG1104	cysteine desulfurase activity
TD68_10540	COG1959	2 iron, 2 sulfur cluster binding
TD68_10545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TD68_10550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TD68_10555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TD68_10565	COG3103	Sh3 type 3 domain protein
TD68_10565	COG4991	sh3 domain protein
TD68_10565	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_10570	COG1490	D-aminoacyl-tRNA deacylase activity
TD68_10575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TD68_10585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TD68_10585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TD68_10590	COG5416	Lipopolysaccharide assembly protein A domain
TD68_10595	COG0490	domain, Protein
TD68_10600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD68_10600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD68_10610	COG2244	polysaccharide biosynthetic process
TD68_10615	COG2323	membrane
TD68_10625	COG1862	Preprotein translocase
TD68_10635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TD68_10645	COG2255	four-way junction helicase activity
TD68_10660	COG2814	Major facilitator Superfamily
TD68_10665	COG2112	serine threonine protein kinase
TD68_10675	COG1115	amino acid carrier protein
TD68_10680	COG0217	transcriptional regulatory protein
TD68_10695	COG3394	polysaccharide catabolic process
TD68_10705	COG1486	melibiose metabolic process
TD68_10710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_10715	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD68_10720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_10730	COG1388	LysM domain
TD68_10735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TD68_10740	COG0157	Belongs to the NadC ModD family
TD68_10745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TD68_10750	COG1104	cysteine desulfurase activity
TD68_10755	COG1827	regulation of RNA biosynthetic process
TD68_10760	COG0077	Prephenate dehydratase
TD68_10765	COG4492	Belongs to the UPF0735 family
TD68_10770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TD68_10775	COG3290	protein histidine kinase activity
TD68_10780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TD68_10785	COG2868	ribosomal protein
TD68_10790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TD68_10795	COG1994	Peptidase M50
TD68_10800	COG0739	heme binding
TD68_10805	COG2894	cell division
TD68_10810	COG0850	regulation of cytokinetic process
TD68_10815	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
TD68_10820	COG1792	Involved in formation and maintenance of cell shape
TD68_10825	COG1077	Cell shape determining protein MreB Mrl
TD68_10830	COG2003	Belongs to the UPF0758 family
TD68_10835	COG0424	maF-like protein
TD68_10845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TD68_10850	COG0285	dihydrofolate synthase activity
TD68_10855	COG0525	valine-tRNA ligase activity
TD68_10865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_10870	COG1388	LysM domain
TD68_10870	COG1388	LysM domain
TD68_10875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TD68_10880	COG0113	porphobilinogen synthase activity
TD68_10885	COG1587	Uroporphyrinogen-III synthase
TD68_10895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD68_10900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TD68_10910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TD68_10915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TD68_10920	COG0470	DNA polymerase III
TD68_10920	COG1067	ATP-dependent peptidase activity
TD68_10930	COG0544	peptidyl-prolyl cis-trans isomerase activity
TD68_10935	COG0457	Tetratricopeptide repeat
TD68_10935	COG1477	protein flavinylation
TD68_10940	COG0066	3-isopropylmalate dehydratase activity
TD68_10945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TD68_10950	COG0473	3-isopropylmalate dehydrogenase activity
TD68_10955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TD68_10960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TD68_10965	COG0440	acetolactate synthase activity
TD68_10970	COG0028	Belongs to the TPP enzyme family
TD68_10975	COG0454	-acetyltransferase
TD68_10980	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
TD68_10990	COG0622	Phosphoesterase
TD68_10995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TD68_11000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TD68_11005	COG5401	PFAM Sporulation and spore germination
TD68_11010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TD68_11015	COG1846	Transcriptional regulator
TD68_11020	COG2197	response regulator
TD68_11025	COG0824	Thioesterase
TD68_11030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TD68_11035	COG1053	succinate dehydrogenase
TD68_11040	COG2009	succinate dehydrogenase
TD68_11045	COG1719	4-vinyl reductase, 4VR
TD68_11050	COG0527	aspartate kinase activity
TD68_11055	COG0322	excinuclease ABC activity
TD68_11060	COG3118	belongs to the thioredoxin family
TD68_11065	COG3534	alpha-L-arabinofuranosidase
TD68_11070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TD68_11075	COG2086	electron transfer activity
TD68_11080	COG1024	Enoyl-CoA hydratase
TD68_11085	COG1309	transcriptional regulator
TD68_11090	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_11095	COG3766	membrane
TD68_11100	COG1193	negative regulation of DNA recombination
TD68_11105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD68_11105	COG1796	DNA polymerase
TD68_11110	COG1286	toxin biosynthetic process
TD68_11115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
TD68_11125	COG0072	phenylalanine-tRNA ligase activity
TD68_11125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_11130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TD68_11135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD68_11145	COG3835	regulator
TD68_11150	COG0277	FAD linked oxidase domain protein
TD68_11155	COG0247	lactate metabolic process
TD68_11160	COG0346	lactoylglutathione lyase activity
TD68_11165	COG1966	Carbon starvation protein
TD68_11170	COG3534	alpha-L-arabinofuranosidase
TD68_11175	COG0395	ABC-type sugar transport system, permease component
TD68_11180	COG1175	transmembrane transport
TD68_11185	COG1653	transport
TD68_11190	COG0371	Dehydrogenase
TD68_11195	COG0647	UMP catabolic process
TD68_11200	COG0235	Class ii aldolase
TD68_11205	COG1069	ribulokinase activity
TD68_11210	COG2160	L-arabinose isomerase activity
TD68_11235	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_11240	COG1363	Peptidase, m42
TD68_11250	COG3326	Membrane
TD68_11255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TD68_11260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TD68_11265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TD68_11280	COG1346	cytolysis
TD68_11290	COG3279	Response regulator of the LytR AlgR family
TD68_11295	COG3275	phosphorelay sensor kinase activity
TD68_11305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TD68_11315	COG0398	Pfam SNARE associated Golgi protein
TD68_11320	COG1484	DNA-dependent DNA replication
TD68_11325	COG3611	Membrane attachment protein
TD68_11330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TD68_11335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TD68_11340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD68_11345	COG1733	regulation of RNA biosynthetic process
TD68_11350	COG2814	Major facilitator Superfamily
TD68_11355	COG0656	L-ascorbic acid biosynthetic process
TD68_11360	COG0237	dephospho-CoA kinase activity
TD68_11365	COG1971	Probably functions as a manganese efflux pump
TD68_11370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TD68_11375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_11375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_11380	COG5002	protein histidine kinase activity
TD68_11385	COG0745	RESPONSE REGULATOR receiver
TD68_11395	COG0538	isocitrate dehydrogenase activity
TD68_11400	COG0372	Belongs to the citrate synthase family
TD68_11405	COG2707	UPF0756 membrane protein
TD68_11410	COG0628	permease
TD68_11415	COG3030	protein affecting phage T7 exclusion by the F plasmid
TD68_11420	COG0469	pyruvate kinase activity
TD68_11430	COG0825	malonyl-CoA metabolic process
TD68_11435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TD68_11440	COG0281	malic enzyme
TD68_11445	COG0587	DNA-directed DNA polymerase activity
TD68_11465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TD68_11475	COG4109	DRTGG domain
TD68_11480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TD68_11485	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_11490	COG0165	Argininosuccinate lyase
TD68_11495	COG0137	argininosuccinate synthase activity
TD68_11500	COG0521	Mo-molybdopterin cofactor biosynthetic process
TD68_11505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TD68_11510	COG0827	DNA restriction-modification system
TD68_11515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TD68_11520	COG3874	Sporulation protein YtfJ
TD68_11530	COG1714	RDD family
TD68_11535	COG0616	signal peptide processing
TD68_11540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD68_11545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TD68_11550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD68_11560	COG0301	tRNA thio-modification
TD68_11565	COG1104	cysteine desulfurase activity
TD68_11570	COG1114	Component of the transport system for branched-chain amino acids
TD68_11575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
TD68_11580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD68_11585	COG1309	transcriptional regulator
TD68_11590	COG1956	GAF domain-containing protein
TD68_11595	COG2203	Gaf domain
TD68_11595	COG2199	diguanylate cyclase activity
TD68_11605	COG2267	carboxylic ester hydrolase activity
TD68_11620	COG1335	isochorismatase
TD68_11635	COG1846	Transcriptional regulator
TD68_11640	COG2259	Doxx family
TD68_11645	COG0346	lactoylglutathione lyase activity
TD68_11650	COG0400	carboxylic ester hydrolase activity
TD68_11660	COG0697	spore germination
TD68_11665	COG0583	DNA-binding transcription factor activity
TD68_11670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD68_11675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD68_11680	COG0454	-acetyltransferase
TD68_11685	COG0517	IMP dehydrogenase activity
TD68_11690	COG0123	including yeast histone deacetylase and acetoin utilization protein
TD68_11695	COG1360	Flagellar Motor Protein
TD68_11700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD68_11705	COG1609	Transcriptional regulator
TD68_11710	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TD68_11710	COG1605	Chorismate mutase
TD68_11715	COG3118	belongs to the thioredoxin family
TD68_11720	COG4980	gas vesicle protein
TD68_11725	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
TD68_11735	COG1674	ftsk spoiiie
TD68_11740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_11745	COG4848	Belongs to the UPF0354 family
TD68_11750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_11760	COG1363	Peptidase, m42
TD68_11765	COG5584	Small secreted protein
TD68_11770	COG0281	malic enzyme
TD68_11775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_11780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TD68_11790	COG0510	thiamine kinase activity
TD68_11795	COG1523	belongs to the glycosyl hydrolase 13 family
TD68_11800	COG1597	lipid kinase activity
TD68_11810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TD68_11815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_11820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_11825	COG2252	PERMEase
TD68_11830	COG1349	DNA-binding transcription factor activity
TD68_11835	COG1187	pseudouridine synthase activity
TD68_11840	COG2244	polysaccharide biosynthetic process
TD68_11845	COG2081	HI0933 family
TD68_11850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TD68_11860	COG5578	integral membrane protein
TD68_11865	COG0673	inositol 2-dehydrogenase activity
TD68_11870	COG1653	transport
TD68_11875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TD68_11880	COG4209	transmembrane transport
TD68_11890	COG1653	transport
TD68_11895	COG0395	ABC-type sugar transport system, permease component
TD68_11900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_11905	COG2124	cytochrome p450
TD68_11910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TD68_11920	COG0156	8-amino-7-oxononanoate synthase activity
TD68_11925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_11930	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
TD68_11935	COG1073	alpha beta
TD68_11940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_11945	COG0495	leucyl-tRNA aminoacylation
TD68_11955	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_11955	COG2202	Pas domain
TD68_11960	COG2814	Major facilitator Superfamily
TD68_11965	COG2433	Pfam Transposase IS66
TD68_11970	COG0577	efflux transmembrane transporter activity
TD68_11975	COG1136	(ABC) transporter
TD68_11980	COG2205	protein histidine kinase activity
TD68_11985	COG0745	RESPONSE REGULATOR receiver
TD68_11990	COG0577	efflux transmembrane transporter activity
TD68_11995	COG1136	(ABC) transporter
TD68_12010	COG1131	(ABC) transporter
TD68_12015	COG1725	Transcriptional regulator
TD68_12030	COG0477	Major facilitator Superfamily
TD68_12035	COG1242	4 iron, 4 sulfur cluster binding
TD68_12040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TD68_12050	COG2267	carboxylic ester hydrolase activity
TD68_12055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
TD68_12060	COG1113	amino acid transport
TD68_12065	COG0367	asparagine synthase
TD68_12075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TD68_12085	COG1506	peptidase
TD68_12090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD68_12095	COG1116	anion transmembrane transporter activity
TD68_12100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD68_12105	COG0494	nUDIX hydrolase
TD68_12115	COG4824	toxin secretion phage lysis holin
TD68_12120	COG0783	Belongs to the Dps family
TD68_12140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TD68_12145	COG0288	reversible hydration of carbon dioxide
TD68_12150	COG0523	cobalamin synthesis protein
TD68_12160	COG1271	oxidase subunit
TD68_12165	COG1294	oxidase, subunit
TD68_12170	COG4305	rare lipoprotein A
TD68_12175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_12180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_12180	COG1321	iron dependent repressor
TD68_12185	COG1121	(ABC) transporter
TD68_12190	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD68_12195	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_12200	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_12205	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TD68_12210	COG0596	Alpha beta hydrolase
TD68_12215	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TD68_12220	COG1169	isochorismate synthase
TD68_12225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_12235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_12240	COG0438	transferase activity, transferring glycosyl groups
TD68_12250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_12255	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
TD68_12260	COG0058	SHG alpha-glucan phosphorylase activity
TD68_12265	COG0297	glycogen (starch) synthase activity
TD68_12270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD68_12275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD68_12280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TD68_12405	COG3859	Proton-coupled thiamine transporter YuaJ
TD68_12410	COG3764	Sortase (surface protein transpeptidase)
TD68_12425	COG2268	Band 7 protein
TD68_12430	COG1585	Membrane protein implicated in regulation of membrane protease activity
TD68_12435	COG2318	DinB family
TD68_12445	COG1454	alcohol dehydrogenase
TD68_12455	COG1510	regulation of RNA biosynthetic process
TD68_12465	COG0569	domain protein
TD68_12470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD68_12475	COG4682	membrane
TD68_12480	COG1705	Flagellar rod assembly protein muramidase FlgJ
TD68_12485	COG0477	Major facilitator Superfamily
TD68_12500	COG0628	permease
TD68_12505	COG0673	inositol 2-dehydrogenase activity
TD68_12510	COG0693	protein deglycase activity
TD68_12515	COG4806	L-rhamnose isomerase
TD68_12520	COG3254	rhamnose metabolic process
TD68_12525	COG1070	Carbohydrate kinase
TD68_12530	COG1349	DNA-binding transcription factor activity
TD68_12535	COG3347	Dehydrogenase
TD68_12535	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_12540	COG0840	transmembrane signaling receptor activity
TD68_12545	COG0840	transmembrane signaling receptor activity
TD68_12550	COG0840	transmembrane signaling receptor activity
TD68_12555	COG0840	transmembrane signaling receptor activity
TD68_12570	COG2070	2-Nitropropane dioxygenase
TD68_12575	COG0432	Pfam Uncharacterised protein family UPF0047
TD68_12580	COG0366	Alpha amylase catalytic
TD68_12585	COG1253	flavin adenine dinucleotide binding
TD68_12590	COG2738	Putative neutral zinc metallopeptidase
TD68_12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TD68_12620	COG0166	Belongs to the GPI family
TD68_12625	COG1979	alcohol dehydrogenase
TD68_12630	COG1979	alcohol dehydrogenase
TD68_12635	COG2155	Conserved Protein
TD68_12640	COG1098	S1 RNA binding domain
TD68_12645	COG0436	Aminotransferase
TD68_12650	COG1522	sequence-specific DNA binding
TD68_12655	COG2267	carboxylic ester hydrolase activity
TD68_12665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TD68_12670	COG2205	protein histidine kinase activity
TD68_12680	COG5018	Exonuclease
TD68_12690	COG2814	Major facilitator Superfamily
TD68_12695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_12700	COG3011	Protein conserved in bacteria
TD68_12710	COG3290	protein histidine kinase activity
TD68_12715	COG4565	transcriptional regulatory protein
TD68_12740	COG3493	citrate carrier protein
TD68_12750	COG2111	Na H antiporter
TD68_12750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD68_12755	COG2111	Na H antiporter
TD68_12760	COG1006	Multisubunit Na H antiporter MnhC subunit
TD68_12765	COG0651	ATP synthesis coupled electron transport
TD68_12770	COG1863	multisubunit Na H antiporter MnhE subunit
TD68_12775	COG2212	antiporter activity
TD68_12780	COG1320	monovalent cation:proton antiporter activity
TD68_12785	COG2050	protein possibly involved in aromatic compounds catabolism
TD68_12790	COG2197	response regulator
TD68_12795	COG4585	Histidine kinase
TD68_12805	COG0142	geranyltranstransferase activity
TD68_12820	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
TD68_12825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TD68_12830	COG1335	isochorismatase
TD68_12835	COG5506	Protein of unknown function (DUF1694)
TD68_12850	COG0628	permease
TD68_12860	COG1418	mRNA catabolic process
TD68_12865	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_12875	COG1511	domain protein
TD68_12880	COG2508	Transcriptional regulator
TD68_12880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
TD68_12885	COG0686	Belongs to the AlaDH PNT family
TD68_12890	COG5634	Uncharacterized conserved protein (DUF2278)
TD68_12895	COG3251	PFAM MbtH domain protein
TD68_12900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_12905	COG1535	isochorismatase
TD68_12905	COG3433	isochorismatase activity
TD68_12910	COG1021	2,3-dihydroxybenzoate-AMP ligase
TD68_12915	COG1169	isochorismate synthase
TD68_12920	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_12925	COG2819	hydrolase of the alpha beta superfamily
TD68_12940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TD68_12945	COG1268	BioY protein
TD68_12950	COG2056	Na+-H+ antiporter family
TD68_12955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TD68_12960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TD68_12965	COG3584	3D domain protein
TD68_12975	COG1252	NADH dehydrogenase
TD68_12985	COG0516	GMP reductase activity
TD68_12990	COG0316	Belongs to the HesB IscA family
TD68_12995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TD68_13000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_13005	COG4844	belongs to the
TD68_13010	COG1252	NADH dehydrogenase
TD68_13015	COG3479	Phenolic acid decarboxylase
TD68_13020	COG4837	Protein of unknown function (DUF1462)
TD68_13025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TD68_13030	COG4946	Tricorn protease homolog
TD68_13030	COG1506	peptidase
TD68_13030	COG0823	Involved in the tonB-independent uptake of proteins
TD68_13035	COG0083	homoserine kinase activity
TD68_13040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TD68_13045	COG0460	homoserine dehydrogenase
TD68_13050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_13055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TD68_13060	COG0647	UMP catabolic process
TD68_13065	COG2445	Protein of unknown function DUF86
TD68_13070	COG4470	Protein conserved in bacteria
TD68_13085	COG0739	heme binding
TD68_13095	COG3377	Domain of unknown function (DUF1805)
TD68_13100	COG0737	Belongs to the 5'-nucleotidase family
TD68_13105	COG0730	response to heat
TD68_13110	COG1801	Protein of unknown function DUF72
TD68_13125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TD68_13130	COG2508	Transcriptional regulator
TD68_13135	COG2233	PERMEase
TD68_13140	COG1595	DNA-templated transcription, initiation
TD68_13195	COG1131	(ABC) transporter
TD68_13205	COG2080	2 iron, 2 sulfur cluster binding
TD68_13220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
TD68_13225	COG2814	Major facilitator Superfamily
TD68_13230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TD68_13235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_13240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TD68_13245	COG2356	endonuclease I
TD68_13255	COG3842	ATPase activity
TD68_13260	COG2188	Transcriptional regulator
TD68_13265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_13270	COG0395	ABC-type sugar transport system, permease component
TD68_13275	COG1175	transmembrane transport
TD68_13280	COG1653	transport
TD68_13285	COG2222	sugar isomerase
TD68_13290	COG0322	excinuclease ABC activity
TD68_13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_13300	COG0719	Fe-S assembly protein
TD68_13305	COG0822	iron-sulfur transferase activity
TD68_13310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TD68_13315	COG0719	Fe-S assembly protein
TD68_13320	COG0396	ATPase activity
TD68_13325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TD68_13330	COG1464	Belongs to the NlpA lipoprotein family
TD68_13335	COG2011	ABC-type metal ion transport system permease component
TD68_13340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TD68_13350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_13355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD68_13365	COG0509	glycine decarboxylation via glycine cleavage system
TD68_13370	COG1393	Belongs to the ArsC family
TD68_13375	COG1960	acyl-CoA dehydrogenase activity
TD68_13380	COG0183	Belongs to the thiolase family
TD68_13385	COG1024	Enoyl-CoA hydratase
TD68_13385	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD68_13400	COG5577	PFAM Coat F domain
TD68_13405	COG1846	Transcriptional regulator
TD68_13410	COG0477	Major facilitator Superfamily
TD68_13420	COG1120	ATPase activity
TD68_13435	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_13440	COG0783	Belongs to the Dps family
TD68_13445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_13450	COG0745	RESPONSE REGULATOR receiver
TD68_13455	COG2205	protein histidine kinase activity
TD68_13455	COG2770	Histidine kinase
TD68_13460	COG1309	transcriptional regulator
TD68_13465	COG0114	fumarate hydratase activity
TD68_13475	COG0697	spore germination
TD68_13480	COG0814	amino acid
TD68_13490	COG2197	response regulator
TD68_13495	COG4585	Histidine kinase
TD68_13500	COG4758	membrane
TD68_13505	COG3595	metallopeptidase activity
TD68_13510	COG1842	Phage shock protein A
TD68_13515	COG4758	membrane
TD68_13520	COG2814	Major facilitator Superfamily
TD68_13525	COG2096	Adenosyltransferase
TD68_13530	COG1120	ATPase activity
TD68_13535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_13540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_13545	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_13550	COG3386	PFAM SMP-30 Gluconolaconase
TD68_13555	COG2205	protein histidine kinase activity
TD68_13560	COG0745	RESPONSE REGULATOR receiver
TD68_13570	COG1191	sigma factor activity
TD68_13575	COG2140	Oxalate decarboxylase
TD68_13585	COG0577	efflux transmembrane transporter activity
TD68_13590	COG1136	(ABC) transporter
TD68_13595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TD68_13600	COG1120	ATPase activity
TD68_13605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_13610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_13615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_13620	COG0531	amino acid
TD68_13635	COG1988	membrane-bound metal-dependent
TD68_13640	COG1368	sulfuric ester hydrolase activity
TD68_13645	COG1910	domain protein
TD68_13650	COG0725	ABC transporter, periplasmic molybdate-binding protein
TD68_13655	COG4149	molybdate abc transporter
TD68_13665	COG0656	L-ascorbic acid biosynthetic process
TD68_13690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_13695	COG3973	AAA domain
TD68_13700	COG2860	membrane
TD68_13710	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TD68_13715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TD68_13720	COG2217	Heavy metal translocating P-type atpase
TD68_13725	COG2217	Heavy metal translocating P-type atpase
TD68_13730	COG2608	mercury ion transmembrane transporter activity
TD68_13735	COG1937	Protein conserved in bacteria
TD68_13740	COG0673	inositol 2-dehydrogenase activity
TD68_13745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD68_13750	COG1289	transmembrane transporter activity
TD68_13755	COG1846	Transcriptional regulator
TD68_13765	COG2076	Multidrug Resistance protein
TD68_13770	COG1309	transcriptional regulator
TD68_13775	COG1442	glycosyl transferase family 8
TD68_13775	COG1216	Glycosyl transferase, family 2
TD68_13780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TD68_13785	COG0557	exoribonuclease II activity
TD68_13790	COG1647	Serine aminopeptidase, S33
TD68_13795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD68_13800	COG1476	TRANSCRIPTIONal
TD68_13805	COG1396	sequence-specific DNA binding
TD68_13810	COG1396	sequence-specific DNA binding
TD68_13815	COG1733	regulation of RNA biosynthetic process
TD68_13820	COG0840	transmembrane signaling receptor activity
TD68_13825	COG1174	glycine betaine transport
TD68_13830	COG1732	Glycine betaine
TD68_13835	COG1174	glycine betaine transport
TD68_13840	COG0517	IMP dehydrogenase activity
TD68_13840	COG1125	glycine betaine transport
TD68_13845	COG1510	regulation of RNA biosynthetic process
TD68_13850	COG1174	glycine betaine transport
TD68_13855	COG1732	Glycine betaine
TD68_13860	COG1174	glycine betaine transport
TD68_13865	COG1125	glycine betaine transport
TD68_13865	COG0517	IMP dehydrogenase activity
TD68_13870	COG1510	regulation of RNA biosynthetic process
TD68_13875	COG2095	MarC family integral membrane protein
TD68_13880	COG3064	Membrane
TD68_13885	COG4640	response to antibiotic
TD68_13890	COG0456	acetyltransferase
TD68_13905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_13925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_13930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_13940	COG2234	aminopeptidase activity
TD68_13950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TD68_13960	COG0126	phosphoglycerate kinase activity
TD68_13965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD68_13970	COG2390	Transcriptional regulator
TD68_13975	COG2814	Major facilitator Superfamily
TD68_13980	COG1609	Transcriptional regulator
TD68_13985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_13990	COG0583	DNA-binding transcription factor activity
TD68_13995	COG0697	spore germination
TD68_14000	COG1113	amino acid transport
TD68_14005	COG3858	chitin binding
TD68_14010	COG1556	Lactate utilization protein
TD68_14015	COG1139	Iron-sulfur cluster binding protein
TD68_14020	COG0247	lactate metabolic process
TD68_14025	COG2186	Transcriptional regulator
TD68_14030	COG1620	l-lactate permease
TD68_14035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
TD68_14045	COG5039	Polysaccharide pyruvyl transferase
TD68_14050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_14055	COG0110	maltose O-acetyltransferase activity
TD68_14060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TD68_14065	COG2244	polysaccharide biosynthetic process
TD68_14070	COG1216	Glycosyl transferase, family 2
TD68_14075	COG5039	Polysaccharide pyruvyl transferase
TD68_14080	COG1216	Glycosyl transferase, family 2
TD68_14090	COG0438	transferase activity, transferring glycosyl groups
TD68_14095	COG1215	transferase activity, transferring glycosyl groups
TD68_14100	COG0438	transferase activity, transferring glycosyl groups
TD68_14105	COG1086	Polysaccharide biosynthesis protein
TD68_14110	COG0489	protein tyrosine kinase activity
TD68_14115	COG3944	biosynthesis protein
TD68_14120	COG1396	sequence-specific DNA binding
TD68_14140	COG1131	(ABC) transporter
TD68_14160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TD68_14165	COG0583	DNA-binding transcription factor activity
TD68_14170	COG1621	beta-fructofuranosidase activity
TD68_14175	COG1621	beta-fructofuranosidase activity
TD68_14180	COG0531	amino acid
TD68_14185	COG1309	transcriptional regulator
TD68_14190	COG2076	Multidrug Resistance protein
TD68_14195	COG2076	Multidrug Resistance protein
TD68_14200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_14225	COG1611	Belongs to the LOG family
TD68_14230	COG1694	Mazg nucleotide pyrophosphohydrolase
TD68_14235	COG0659	secondary active sulfate transmembrane transporter activity
TD68_14240	COG0288	reversible hydration of carbon dioxide
TD68_14245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD68_14250	COG0577	efflux transmembrane transporter activity
TD68_14255	COG1136	(ABC) transporter
TD68_14260	COG5002	protein histidine kinase activity
TD68_14265	COG0745	RESPONSE REGULATOR receiver
TD68_14270	COG4290	ribonuclease
TD68_14275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
TD68_14280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_14290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TD68_14295	COG1660	Displays ATPase and GTPase activities
TD68_14300	COG1051	belongs to the nudix hydrolase family
TD68_14305	COG0492	ferredoxin-NADP+ reductase activity
TD68_14310	COG0791	NLP P60 protein
TD68_14310	COG3883	PFAM NLP P60 protein
TD68_14315	COG0457	Tetratricopeptide repeat
TD68_14320	COG1132	(ABC) transporter
TD68_14330	COG1247	-acetyltransferase
TD68_14335	COG0140	phosphoribosyl-ATP diphosphatase activity
TD68_14335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TD68_14340	COG0107	imidazoleglycerol-phosphate synthase activity
TD68_14345	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TD68_14355	COG0131	Imidazoleglycerol-phosphate dehydratase
TD68_14360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TD68_14365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TD68_14370	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TD68_14375	COG4990	cell redox homeostasis
TD68_14380	COG5297	Belongs to the glycosyl hydrolase family 6
TD68_14385	COG0110	maltose O-acetyltransferase activity
TD68_14390	COG0546	phosphoglycolate phosphatase activity
TD68_14395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TD68_14400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TD68_14405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TD68_14410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TD68_14425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TD68_14430	COG1950	PFAM Membrane protein of
TD68_14435	COG1983	PspC domain protein
TD68_14440	COG3595	metallopeptidase activity
TD68_14455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TD68_14465	COG4897	Protein conserved in bacteria
TD68_14470	COG3848	Pyruvate phosphate dikinase
TD68_14470	COG0574	Belongs to the PEP-utilizing enzyme family
TD68_14475	COG1309	transcriptional regulator
TD68_14480	COG2814	Major facilitator Superfamily
TD68_14495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_14505	COG3409	Peptidoglycan-binding domain 1 protein
TD68_14505	COG0793	Belongs to the peptidase S41A family
TD68_14510	COG2177	Part of the ABC transporter FtsEX involved in
TD68_14515	COG2884	Cell division ATP-binding protein ftsE
TD68_14520	COG2010	Cytochrome c
TD68_14525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_14530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TD68_14535	COG0653	protein targeting
TD68_14540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TD68_14555	COG1516	flagellar protein fliS
TD68_14560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TD68_14565	COG1334	flagellar protein FlaG
TD68_14570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD68_14575	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TD68_14580	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TD68_14590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD68_14595	COG4786	Flagellar basal body rod
TD68_14595	COG1256	bacterial-type flagellum assembly
TD68_14600	COG3418	PFAM FlgN family protein
TD68_14605	COG2747	anti-sigma28 factor FlgM
TD68_14615	COG1040	competence protein
TD68_14625	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
TD68_14630	COG1307	EDD domain protein, DegV family
TD68_14635	COG2197	response regulator
TD68_14640	COG4585	Histidine kinase
TD68_14645	COG1739	Uncharacterized protein family UPF0029
TD68_14650	COG1316	TRANSCRIPTIONal
TD68_14655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TD68_14660	COG0438	transferase activity, transferring glycosyl groups
TD68_14665	COG1215	transferase activity, transferring glycosyl groups
TD68_14670	COG3206	protein involved in exopolysaccharide biosynthesis
TD68_14675	COG3307	-O-antigen
TD68_14680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_14685	COG0297	glycogen (starch) synthase activity
TD68_14685	COG0438	transferase activity, transferring glycosyl groups
TD68_14690	COG2244	polysaccharide biosynthetic process
TD68_14705	COG2247	cell wall binding repeat
TD68_14705	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_14710	COG2247	cell wall binding repeat
TD68_14710	COG2385	sporulation resulting in formation of a cellular spore
TD68_14720	COG1316	TRANSCRIPTIONal
TD68_14725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TD68_14730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TD68_14735	COG1134	teichoic acid transport
TD68_14740	COG1682	transport, permease protein
TD68_14745	COG0463	Glycosyl transferase, family 2
TD68_14745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_14750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_14755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TD68_14760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
TD68_14765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_14770	COG4193	domain, Protein
TD68_14775	COG1482	cell wall glycoprotein biosynthetic process
TD68_14780	COG0697	spore germination
TD68_14785	COG0814	amino acid
TD68_14795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TD68_14800	COG2814	Major facilitator Superfamily
TD68_14805	COG1316	TRANSCRIPTIONal
TD68_14810	COG0561	phosphatase activity
TD68_14815	COG0791	NLP P60 protein
TD68_14820	COG2843	Capsule synthesis protein
TD68_14830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TD68_14835	COG0697	spore germination
TD68_14840	COG0531	amino acid
TD68_14850	COG1609	Transcriptional regulator
TD68_14855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_14860	COG1869	D-ribose catabolic process
TD68_14865	COG1129	ABC transporter
TD68_14870	COG1172	Belongs to the binding-protein-dependent transport system permease family
TD68_14875	COG1879	ABC-type sugar transport system periplasmic component
TD68_14880	COG3103	Sh3 type 3 domain protein
TD68_14890	COG2249	NAD(P)H dehydrogenase (quinone) activity
TD68_14895	COG3527	Alpha-acetolactate decarboxylase
TD68_14900	COG0028	Belongs to the TPP enzyme family
TD68_14905	COG0583	DNA-binding transcription factor activity
TD68_14910	COG5337	Spore coat protein CotH
TD68_14920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TD68_14925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_14940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TD68_14950	COG0405	Gamma-glutamyltransferase
TD68_14955	COG1522	sequence-specific DNA binding
TD68_14960	COG2059	Chromate
TD68_14965	COG2059	Chromate
TD68_14975	COG0655	NAD(P)H dehydrogenase (quinone) activity
TD68_14980	COG0583	DNA-binding transcription factor activity
TD68_15005	COG5444	nuclease activity
TD68_15025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_15030	COG4464	protein tyrosine phosphatase activity
TD68_15035	COG0489	protein tyrosine kinase activity
TD68_15040	COG3944	biosynthesis protein
TD68_15045	COG4715	Zinc finger, swim domain protein
TD68_15050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD68_15055	COG0561	phosphatase activity
TD68_15060	COG1349	DNA-binding transcription factor activity
TD68_15065	COG0629	single-stranded DNA binding
TD68_15080	COG1970	mechanosensitive ion channel activity
TD68_15090	COG0457	Tetratricopeptide repeat
TD68_15095	COG4786	Flagellar basal body rod
TD68_15100	COG4786	Flagellar basal body rod
TD68_15105	COG1077	Cell shape determining protein MreB Mrl
TD68_15110	COG1609	Transcriptional regulator
TD68_15115	COG1846	Transcriptional regulator
TD68_15120	COG2814	Major facilitator Superfamily
TD68_15125	COG1953	Uracil, thiamine, allantoin
TD68_15130	COG0477	Major facilitator Superfamily
TD68_15135	COG1335	isochorismatase
TD68_15145	COG0004	ammonium transporteR
TD68_15150	COG0347	Belongs to the P(II) protein family
TD68_15155	COG0772	Belongs to the SEDS family
TD68_15160	COG0671	phosphoesterase, PA-phosphatase related
TD68_15170	COG0739	heme binding
TD68_15175	COG1247	-acetyltransferase
TD68_15185	COG1086	Polysaccharide biosynthesis protein
TD68_15190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_15195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_15200	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
TD68_15215	COG2089	acid synthase
TD68_15225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_15230	COG0789	Transcriptional regulator
TD68_15240	COG2910	NAD(P)H-binding
TD68_15250	COG0804	urea catabolic process
TD68_15260	COG0831	urea catabolic process
TD68_15265	COG3237	CsbD-like
TD68_15270	COG1994	Peptidase M50
TD68_15275	COG0457	Tetratricopeptide repeat
TD68_15285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TD68_15290	COG2304	oxidoreductase activity
TD68_15295	COG2304	oxidoreductase activity
TD68_15300	COG2385	sporulation resulting in formation of a cellular spore
TD68_15305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD68_15315	COG4836	Membrane
TD68_15325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TD68_15330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TD68_15335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TD68_15345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TD68_15350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TD68_15355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TD68_15370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TD68_15375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TD68_15380	COG4475	Protein of unknown function (DUF436)
TD68_15385	COG0698	ribose 5-phosphate isomerase
TD68_15390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_15395	COG1971	Probably functions as a manganese efflux pump
TD68_15400	COG0009	L-threonylcarbamoyladenylate synthase
TD68_15405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TD68_15425	COG2890	protein-(glutamine-N5) methyltransferase activity
TD68_15430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TD68_15435	COG0346	lactoylglutathione lyase activity
TD68_15440	COG0789	Transcriptional regulator
TD68_15445	COG0679	Auxin Efflux Carrier
TD68_15450	COG0281	malic enzyme
TD68_15460	COG0254	rRNA binding
TD68_15465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TD68_15470	COG1494	fructose-1,6-bisphosphatase
TD68_15475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD68_15485	COG0191	fructose-bisphosphate aldolase activity
TD68_15490	COG2204	response regulator
TD68_15495	COG4821	SIS domain
TD68_15500	COG0504	CTP synthase activity
TD68_15505	COG3343	RNA polymerase activity
TD68_15510	COG1960	acyl-CoA dehydrogenase activity
TD68_15515	COG2181	nitrate reductase activity
TD68_15515	COG0247	lactate metabolic process
TD68_15520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_15525	COG4294	response to UV
TD68_15535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TD68_15540	COG1132	(ABC) transporter
TD68_15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_15550	COG2181	nitrate reductase activity
TD68_15555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
TD68_15560	COG1140	nitrate reductase beta subunit
TD68_15565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
TD68_15570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD68_15580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD68_15585	COG2223	nitrite transmembrane transporter activity
TD68_15590	COG0018	arginyl-trna synthetase
TD68_15595	COG4506	Protein conserved in bacteria
TD68_15605	COG0535	radical SAM domain protein
TD68_15615	COG1131	(ABC) transporter
TD68_15640	COG3391	amine dehydrogenase activity
TD68_15645	COG3391	amine dehydrogenase activity
TD68_15650	COG1388	LysM domain
TD68_15655	COG0457	Tetratricopeptide repeat
TD68_15665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TD68_15670	COG0010	Belongs to the arginase family
TD68_15675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TD68_15680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_15690	COG1994	Peptidase M50
TD68_15695	COG1942	4-Oxalocrotonate Tautomerase
TD68_15700	COG1846	Transcriptional regulator
TD68_15705	COG0531	amino acid
TD68_15710	COG3465	dGTPase activity
TD68_15715	COG1078	dGTPase activity
TD68_15720	COG4844	belongs to the
TD68_15730	COG0697	spore germination
TD68_15735	COG0095	Lipoate-protein ligase
TD68_15740	COG0583	DNA-binding transcription factor activity
TD68_15750	COG0280	phosphate acetyltransferase
TD68_15760	COG2814	Major facilitator Superfamily
TD68_15765	COG2814	Major facilitator Superfamily
TD68_15775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
TD68_15780	COG1091	dTDP-4-dehydrorhamnose reductase activity
TD68_15785	COG1088	dTDP-glucose 4,6-dehydratase activity
TD68_15790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TD68_15795	COG0456	acetyltransferase
TD68_15800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_15805	COG0463	Glycosyl transferase, family 2
TD68_15815	COG2363	Small membrane protein
TD68_15820	COG2233	PERMEase
TD68_15830	COG1012	belongs to the aldehyde dehydrogenase family
TD68_15835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TD68_15840	COG1216	Glycosyl transferase, family 2
TD68_15850	COG1695	Transcriptional regulator
TD68_15855	COG0351	phosphomethylpyrimidine kinase
TD68_15865	COG0110	maltose O-acetyltransferase activity
TD68_15870	COG1621	beta-fructofuranosidase activity
TD68_15875	COG1263	PTS System
TD68_15875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_15880	COG2116	formate transmembrane transporter activity
TD68_15885	COG3711	transcriptional antiterminator
TD68_15895	COG1404	Belongs to the peptidase S8 family
TD68_15905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_15910	COG0778	Nitroreductase
TD68_15915	COG0772	Belongs to the SEDS family
TD68_15930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
TD68_15940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TD68_15945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TD68_15950	COG2261	transglycosylase associated protein
TD68_15955	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
TD68_15960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TD68_15965	COG2246	polysaccharide biosynthetic process
TD68_15970	COG1309	transcriptional regulator
TD68_15990	COG3162	membrane
TD68_15995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_16000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TD68_16005	COG0352	thiamine-phosphate diphosphorylase activity
TD68_16010	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TD68_16015	COG0583	DNA-binding transcription factor activity
TD68_16020	COG1380	Effector of murein hydrolase LrgA
TD68_16025	COG1346	cytolysis
TD68_16030	COG1131	(ABC) transporter
TD68_16050	COG1346	cytolysis
TD68_16055	COG4895	conserved protein (DUF2196)
TD68_16060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TD68_16065	COG0346	lactoylglutathione lyase activity
TD68_16070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_16080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_16080	COG1263	PTS System
TD68_16085	COG3711	transcriptional antiterminator
TD68_16090	COG1442	glycosyl transferase family 8
TD68_16095	COG5522	Integral membrane protein (intg_mem_TP0381)
TD68_16100	COG2234	aminopeptidase activity
TD68_16105	COG0457	Tetratricopeptide repeat
TD68_16110	COG1846	Transcriptional regulator
TD68_16115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD68_16120	COG2357	RelA SpoT domain protein
TD68_16125	COG1575	Belongs to the MenA family. Type 1 subfamily
TD68_16130	COG0569	domain protein
TD68_16140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_16145	COG1696	Membrane protein involved in D-alanine export
TD68_16155	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
TD68_16160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_16165	COG1486	melibiose metabolic process
TD68_16170	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD68_16175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_16180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_16185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_16185	COG3711	transcriptional antiterminator
TD68_16190	COG2094	Belongs to the DNA glycosylase MPG family
TD68_16200	COG0753	catalase activity
TD68_16210	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_16215	COG1131	(ABC) transporter
TD68_16235	COG1595	DNA-templated transcription, initiation
TD68_16240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TD68_16245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TD68_16250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TD68_16255	COG4988	ABC transporter
TD68_16260	COG1294	oxidase, subunit
TD68_16265	COG1271	oxidase subunit
TD68_16270	COG3493	citrate carrier protein
TD68_16280	COG0726	polysaccharide deacetylase
TD68_16285	COG3842	ATPase activity
TD68_16290	COG2508	Transcriptional regulator
TD68_16300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_16310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TD68_16320	COG4585	Histidine kinase
TD68_16325	COG2197	response regulator
TD68_16330	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD68_16340	COG4894	glucomannan catabolic process
TD68_16345	COG0457	Tetratricopeptide repeat
TD68_16360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_16390	COG2002	toxin-antitoxin pair type II binding
TD68_16400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TD68_16405	COG3829	transcription factor binding
TD68_16405	COG3290	protein histidine kinase activity
TD68_16410	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_16415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TD68_16420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
TD68_16425	COG2610	gluconate transmembrane transporter activity
TD68_16430	COG0500	methyltransferase
TD68_16435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_16450	COG0753	catalase activity
TD68_16450	COG0693	protein deglycase activity
TD68_16455	COG2851	Citrate transporter
TD68_16465	COG3711	transcriptional antiterminator
TD68_16475	COG2270	Major facilitator Superfamily
TD68_16480	COG0513	Belongs to the DEAD box helicase family
TD68_16490	COG1357	PFAM Pentapeptide repeats (8 copies)
TD68_16495	COG3401	FG-GAP repeat protein
TD68_16495	COG2755	lipolytic protein G-D-S-L family
TD68_16525	COG0697	spore germination
TD68_16530	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_16550	COG0589	response to stress
TD68_16555	COG2723	6-phospho-beta-galactosidase activity
TD68_16560	COG1263	PTS System
TD68_16560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_16560	COG2190	(PTS) system
TD68_16565	COG3977	Valine--pyruvate aminotransferase
TD68_16580	COG1181	Belongs to the D-alanine--D-alanine ligase family
TD68_16595	COG0494	nUDIX hydrolase
TD68_16600	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_16610	COG2986	histidine ammonia-lyase
TD68_16615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TD68_16620	COG1228	amidohydrolase
TD68_16625	COG0010	Belongs to the arginase family
TD68_16630	COG0833	amino acid
TD68_16635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TD68_16640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_16645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TD68_16650	COG2390	Transcriptional regulator
TD68_16660	COG3192	ethanolamine utilization protein
TD68_16665	COG1940	carbohydrate kinase activity
TD68_16670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
TD68_16675	COG0561	phosphatase activity
TD68_16700	COG5294	Protein conserved in bacteria
TD68_16705	COG0577	efflux transmembrane transporter activity
TD68_16710	COG1136	(ABC) transporter
TD68_16715	COG2205	protein histidine kinase activity
TD68_16720	COG0745	RESPONSE REGULATOR receiver
TD68_16730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_16745	COG1082	Xylose isomerase domain protein TIM barrel
TD68_16750	COG0673	inositol 2-dehydrogenase activity
TD68_16755	COG2814	Major facilitator Superfamily
TD68_16760	COG1082	Xylose isomerase domain protein TIM barrel
TD68_16765	COG3962	Belongs to the TPP enzyme family
TD68_16770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_16785	COG1349	DNA-binding transcription factor activity
TD68_16790	COG0667	Aldo Keto reductase
TD68_16810	COG2814	Major facilitator Superfamily
TD68_16815	COG0326	Molecular chaperone. Has ATPase activity
TD68_16820	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_16825	COG1309	transcriptional regulator
TD68_16830	COG1012	belongs to the aldehyde dehydrogenase family
TD68_16840	COG1714	RDD family
TD68_16845	COG2311	Membrane
TD68_16850	COG1917	Cupin 2, conserved barrel domain protein
TD68_16855	COG1309	transcriptional regulator
TD68_16870	COG5039	Polysaccharide pyruvyl transferase
TD68_16875	COG1929	Belongs to the glycerate kinase type-1 family
TD68_16880	COG2610	gluconate transmembrane transporter activity
TD68_16885	COG3835	regulator
TD68_16890	COG1802	Transcriptional regulator
TD68_16895	COG1070	Carbohydrate kinase
TD68_16900	COG2610	gluconate transmembrane transporter activity
TD68_16905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TD68_16915	COG0450	alkyl hydroperoxide reductase
TD68_16920	COG3634	alkyl hydroperoxide reductase activity
TD68_16930	COG1113	amino acid transport
TD68_16940	COG1131	(ABC) transporter
TD68_16945	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
TD68_17040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TD68_17050	COG1063	alcohol dehydrogenase
TD68_17065	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
TD68_17070	COG0456	acetyltransferase
TD68_17075	COG0010	Belongs to the arginase family
TD68_17080	COG0833	amino acid
TD68_17085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD68_17090	COG5658	integral membrane protein
TD68_17095	COG0640	Transcriptional regulator
TD68_17100	COG3829	transcription factor binding
TD68_17110	COG0488	(ABC) transporter
TD68_17125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TD68_17130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_17135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TD68_17140	COG4853	Protein conserved in bacteria
TD68_17145	COG4863	YycH protein
TD68_17150	COG5002	protein histidine kinase activity
TD68_17155	COG0745	RESPONSE REGULATOR receiver
TD68_17185	COG0346	lactoylglutathione lyase activity
TD68_17190	COG0305	Participates in initiation and elongation during chromosome replication
TD68_17205	COG2807	transmembrane transport
TD68_17210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TD68_17215	COG0359	binds to the 23S rRNA
TD68_17220	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TD68_17225	COG4241	membrane
TD68_17235	COG5577	PFAM Coat F domain
TD68_17240	COG1733	regulation of RNA biosynthetic process
TD68_17255	COG2271	Major facilitator Superfamily
TD68_17260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_17270	COG0473	3-isopropylmalate dehydrogenase activity
TD68_17275	COG1802	Transcriptional regulator
TD68_17280	COG4978	Transcriptional regulator
TD68_17280	COG0789	Transcriptional regulator
TD68_17290	COG0745	RESPONSE REGULATOR receiver
TD68_17295	COG2205	protein histidine kinase activity
TD68_17305	COG0477	Major facilitator Superfamily
TD68_17315	COG0425	Belongs to the sulfur carrier protein TusA family
TD68_17315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_17330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_17335	COG1331	Highly conserved protein containing a thioredoxin domain
TD68_17340	COG2814	Major facilitator Superfamily
TD68_17340	COG0477	Major facilitator Superfamily
TD68_17345	COG0346	lactoylglutathione lyase activity
TD68_17350	COG1609	Transcriptional regulator
TD68_17355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD68_17360	COG2169	Transcriptional regulator
TD68_17365	COG0708	Exodeoxyribonuclease III
TD68_17370	COG0697	spore germination
TD68_17375	COG1802	Transcriptional regulator
TD68_17390	COG0629	single-stranded DNA binding
TD68_17395	COG0360	Binds together with S18 to 16S ribosomal RNA
TD68_17400	COG0012	GTP binding
TD68_17405	COG0243	molybdopterin cofactor binding
TD68_17410	COG4481	Protein conserved in bacteria
TD68_17415	COG3949	Membrane
TD68_17425	COG1475	DNA binding
TD68_17430	COG1192	Involved in chromosome partitioning
TD68_17440	COG1475	DNA binding
TD68_17445	COG0357	Ribosomal RNA small subunit methyltransferase G
TD68_17450	COG0445	tRNA wobble uridine modification
TD68_17460	COG1847	R3H domain protein
TD68_17465	COG0706	membrane insertase activity
TD68_17470	COG0594	ribonuclease P activity
TD68_17475	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TD68_17480	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TD68_17485	COG0592	DNA-directed DNA polymerase activity
TD68_17490	COG2501	S4 domain
TD68_17495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TD68_17505	COG0187	DNA topoisomerase II activity
TD68_17510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD68_17535	COG0516	GMP reductase activity
TD68_17535	COG0517	IMP dehydrogenase activity
TD68_17540	COG1686	Belongs to the peptidase S11 family
TD68_17565	COG1428	Deoxynucleoside kinase
TD68_17570	COG1428	Deoxynucleoside kinase
TD68_17575	COG1388	LysM domain
TD68_17575	COG3858	chitin binding
TD68_17580	COG1335	isochorismatase
TD68_17585	COG0590	tRNA wobble adenosine to inosine editing
TD68_17590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TD68_17595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TD68_17600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TD68_17635	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
TD68_17640	COG3853	Toxic anion resistance protein (TelA)
TD68_17645	COG1982	Orn Lys Arg decarboxylase major
TD68_17650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TD68_17655	COG3870	Protein conserved in bacteria
TD68_17660	COG1728	Protein conserved in bacteria
TD68_17665	COG0470	DNA polymerase III
TD68_17670	COG1774	PSP1 C-terminal conserved region
TD68_17680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TD68_17685	COG2827	Endonuclease containing a URI domain
TD68_17690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TD68_17695	COG2002	toxin-antitoxin pair type II binding
TD68_17700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_17700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_17705	COG0084	hydrolase, TatD family'
TD68_17710	COG3584	3D domain protein
TD68_17710	COG3583	domain protein
TD68_17715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD68_17720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TD68_17730	COG4466	Protein conserved in bacteria
TD68_17740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TD68_17745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TD68_17750	COG0251	oxidation-reduction process
TD68_17765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TD68_17770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TD68_17775	COG0193	aminoacyl-tRNA hydrolase activity
TD68_17785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TD68_17790	COG2002	toxin-antitoxin pair type II binding
TD68_17795	COG2244	polysaccharide biosynthetic process
TD68_17800	COG3956	TIGRFAM MazG family protein
TD68_17805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TD68_17820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
TD68_17825	COG1098	S1 RNA binding domain
TD68_17840	COG2208	phosphoserine phosphatase activity
TD68_17845	COG2304	oxidoreductase activity
TD68_17850	COG0515	serine threonine protein kinase
TD68_17855	COG0037	tRNA processing
TD68_17865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TD68_17880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD68_17885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_17890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TD68_17895	COG0512	Glutamine amidotransferase of anthranilate synthase
TD68_17900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_17905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TD68_17910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TD68_17915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TD68_17920	COG1396	sequence-specific DNA binding
TD68_17925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD68_17930	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TD68_18015	COG4463	regulation of RNA biosynthetic process
TD68_18020	COG3880	PFAM UvrB UvrC protein
TD68_18025	COG3869	Catalyzes the specific phosphorylation of arginine residues in
TD68_18030	COG0542	response to heat
TD68_18035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TD68_18040	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TD68_18045	COG4956	integral membrane protein (PIN domain superfamily)
TD68_18050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TD68_18055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TD68_18060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TD68_18065	COG1045	serine acetyltransferase
TD68_18070	COG0215	cysteine-tRNA ligase activity
TD68_18075	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
TD68_18080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD68_18085	COG3688	RNA-binding protein containing a PIN domain
TD68_18090	COG1595	DNA-templated transcription, initiation
TD68_18095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TD68_18100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD68_18105	COG0250	Participates in transcription elongation, termination and antitermination
TD68_18110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TD68_18120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TD68_18125	COG0222	ribosome binding
TD68_18130	COG2813	Specifically methylates the guanine in position
TD68_18135	COG0085	RNA polymerase activity
TD68_18145	COG1358	cellular component organization or biogenesis
TD68_18155	COG0049	tRNA binding
TD68_18160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TD68_18170	COG0596	Alpha beta hydrolase
TD68_18175	COG0051	transcription antitermination factor activity, RNA binding
TD68_18180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TD68_18190	COG0089	rRNA binding
TD68_18195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TD68_18200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TD68_18205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TD68_18215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TD68_18220	COG0255	Belongs to the universal ribosomal protein uL29 family
TD68_18225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TD68_18250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TD68_18260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TD68_18265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TD68_18270	COG1841	ribosomal large subunit assembly
TD68_18275	COG0200	Binds to the 23S rRNA
TD68_18280	COG0201	protein transport
TD68_18290	COG0024	Methionine aminopeptidase
TD68_18295	COG2163	COG2163 Ribosomal protein L14E L6E L27E
TD68_18300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TD68_18305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TD68_18310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TD68_18315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TD68_18325	COG0203	ribosomal protein L17
TD68_18330	COG1122	ATPase activity
TD68_18335	COG1122	ATPase activity
TD68_18340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD68_18345	COG0101	tRNA pseudouridine synthase activity
TD68_18355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TD68_18360	COG2226	methyltransferase
TD68_18370	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_18375	COG0489	protein tyrosine kinase activity
TD68_18385	COG2194	sulfuric ester hydrolase activity
TD68_18390	COG0726	polysaccharide deacetylase
TD68_18420	COG0738	Major facilitator superfamily
TD68_18435	COG1063	alcohol dehydrogenase
TD68_18440	COG0659	secondary active sulfate transmembrane transporter activity
TD68_18445	COG0385	Bile acid
TD68_18450	COG2819	hydrolase of the alpha beta superfamily
TD68_18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_18465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_18470	COG2207	Transcriptional regulator
TD68_18470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_18475	COG3876	Protein conserved in bacteria
TD68_18480	COG1472	Belongs to the glycosyl hydrolase 3 family
TD68_18485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_18490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_18490	COG1263	PTS System
TD68_18495	COG1737	Transcriptional regulator
TD68_18500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TD68_18505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_18510	COG1683	Conserved Protein
TD68_18540	COG1595	DNA-templated transcription, initiation
TD68_18545	COG5662	AntiSigma factor
TD68_18550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TD68_18555	COG4856	YbbR-like protein
TD68_18560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TD68_18570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD68_18575	COG3002	Belongs to the UPF0753 family
TD68_18580	COG0288	reversible hydration of carbon dioxide
TD68_18590	COG5609	conserved protein (DUF2294)
TD68_18595	COG0640	Transcriptional regulator
TD68_18600	COG2814	Major facilitator Superfamily
TD68_18605	COG1413	lyase activity
TD68_18630	COG0076	glutamate decarboxylase activity
TD68_18640	COG1346	cytolysis
TD68_18645	COG1380	Effector of murein hydrolase LrgA
TD68_18650	COG1846	Transcriptional regulator
TD68_18655	COG1113	amino acid transport
TD68_18670	COG2602	Beta-lactamase
TD68_18675	COG2124	cytochrome p450
TD68_18685	COG0531	amino acid
TD68_18690	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_18695	COG2271	Major facilitator Superfamily
TD68_18710	COG1134	teichoic acid transport
TD68_18720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_18735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TD68_18755	COG3409	Peptidoglycan-binding domain 1 protein
TD68_18760	COG0697	spore germination
TD68_18765	COG0371	Dehydrogenase
TD68_18770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
TD68_18780	COG0596	Alpha beta hydrolase
TD68_18785	COG1183	phosphatidylcholine synthase activity
TD68_18790	COG0586	Pfam SNARE associated Golgi protein
TD68_18795	COG0688	phosphatidylethanolamine metabolic process
TD68_18800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_18810	COG1404	Belongs to the peptidase S8 family
TD68_18815	COG2312	Erythromycin esterase
TD68_18820	COG2207	Transcriptional regulator
TD68_18830	COG1301	dicarboxylic acid transport
TD68_18835	COG2190	(PTS) system
TD68_18835	COG1263	PTS System
TD68_18835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_18835	COG2190	(PTS) system
TD68_18835	COG1263	PTS System
TD68_18835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_18840	COG0363	glucosamine-6-phosphate deaminase activity
TD68_18855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_18860	COG0833	amino acid
TD68_18865	COG2040	homocysteine
TD68_18870	COG1115	amino acid carrier protein
TD68_18875	COG2066	Belongs to the glutaminase family
TD68_18880	COG4191	Histidine kinase
TD68_18885	COG0784	Response regulator, receiver
TD68_18890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TD68_18895	COG1012	belongs to the aldehyde dehydrogenase family
TD68_18900	COG2271	Major facilitator Superfamily
TD68_18905	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_18910	COG2186	Transcriptional regulator
TD68_18915	COG2721	sulfolactate sulfo-lyase activity
TD68_18920	COG3173	Aminoglycoside phosphotransferase
TD68_18935	COG0745	RESPONSE REGULATOR receiver
TD68_18940	COG2205	protein histidine kinase activity
TD68_18945	COG1131	(ABC) transporter
TD68_18970	COG3773	Cell wall hydrolase
TD68_18975	COG3540	Alkaline phosphatase
TD68_18980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TD68_18985	COG0805	protein transport
TD68_18995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TD68_19000	COG0477	Major facilitator Superfamily
TD68_19005	COG1309	transcriptional regulator
TD68_19010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
TD68_19015	COG3012	SEC-C Motif Domain Protein
TD68_19015	COG1405	negative regulation of cell septum assembly
TD68_19020	COG0667	Aldo Keto reductase
TD68_19030	COG1595	DNA-templated transcription, initiation
TD68_19035	COG0735	belongs to the Fur family
TD68_19040	COG1595	DNA-templated transcription, initiation
TD68_19045	COG1876	peptidase activity
TD68_19050	COG0457	Tetratricopeptide repeat
TD68_19055	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_19060	COG0366	Alpha amylase catalytic
TD68_19065	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD68_19070	COG1121	(ABC) transporter
TD68_19075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_19080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_19085	COG2310	stress, protein
TD68_19090	COG2310	stress, protein
TD68_19095	COG2310	stress, protein
TD68_19100	COG0861	Integral membrane protein TerC family
TD68_19130	COG3853	Toxic anion resistance protein (TelA)
TD68_19135	COG0477	Major facilitator Superfamily
TD68_19140	COG4175	Glycine betaine
TD68_19140	COG0517	IMP dehydrogenase activity
TD68_19145	COG4176	ABC-type proline glycine betaine transport system permease component
TD68_19150	COG2113	Glycine betaine
TD68_19155	COG1473	amidohydrolase
TD68_19160	COG1288	antiporter activity
TD68_19170	COG0039	L-malate dehydrogenase activity
TD68_19175	COG1620	l-lactate permease
TD68_19180	COG2814	Major facilitator Superfamily
TD68_19185	COG1846	Transcriptional regulator
TD68_19190	COG1280	lysine exporter protein (LysE YggA)
TD68_19195	COG3403	YqcI/YcgG family
TD68_19200	COG1113	amino acid transport
TD68_19205	COG3665	Urea carboxylase-associated protein
TD68_19215	COG1660	Displays ATPase and GTPase activities
TD68_19220	COG1082	Xylose isomerase domain protein TIM barrel
TD68_19225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TD68_19235	COG3458	cephalosporin-C deacetylase activity
TD68_19240	COG3541	Predicted nucleotidyltransferase
TD68_19245	COG0506	proline dehydrogenase activity
TD68_19250	COG1012	belongs to the aldehyde dehydrogenase family
TD68_19255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_19260	COG2508	Transcriptional regulator
TD68_19280	COG3689	TIGRFAM TIGR03943 family protein
TD68_19285	COG0701	Predicted permease
TD68_19290	COG2267	carboxylic ester hydrolase activity
TD68_19295	COG0492	ferredoxin-NADP+ reductase activity
TD68_19300	COG1587	Uroporphyrinogen-III synthase
TD68_19300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TD68_19305	COG2146	nitrite reductase [NAD(P)H] activity
TD68_19310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD68_19315	COG0243	molybdopterin cofactor binding
TD68_19320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD68_19325	COG2223	nitrite transmembrane transporter activity
TD68_19330	COG1469	GTP cyclohydrolase I activity
TD68_19335	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_19340	COG0523	cobalamin synthesis protein
TD68_19345	COG0765	amino acid transport
TD68_19350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_19355	COG1063	alcohol dehydrogenase
TD68_19360	COG1714	RDD family
TD68_19385	COG2723	6-phospho-beta-galactosidase activity
TD68_19395	COG3209	COG3209 Rhs family protein
TD68_19400	COG0840	transmembrane signaling receptor activity
TD68_19400	COG3290	protein histidine kinase activity
TD68_19405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TD68_19410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TD68_19415	COG1733	regulation of RNA biosynthetic process
TD68_19420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_19430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_19435	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
TD68_19445	COG0697	spore germination
TD68_19450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_19460	COG2364	Membrane
TD68_19465	COG1126	abc transporter atp-binding protein
TD68_19470	COG0765	amino acid transport
TD68_19475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_19480	COG0583	DNA-binding transcription factor activity
TD68_19485	COG0163	prenyltransferase activity
TD68_19490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TD68_19505	COG0596	Alpha beta hydrolase
TD68_19510	COG3104	oligopeptide transport
TD68_19515	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_19525	COG0697	spore germination
TD68_19535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TD68_19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_19555	COG0765	amino acid transport
TD68_19560	COG1126	abc transporter atp-binding protein
TD68_19570	COG2079	MmgE PrpD family protein
TD68_19575	COG0457	Tetratricopeptide repeat
TD68_19585	COG0527	aspartate kinase activity
TD68_19590	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_19595	COG4605	iron ion homeostasis
TD68_19600	COG4604	ABC transporter, ATP-binding protein
TD68_19605	COG4607	ABC-type enterochelin transport system periplasmic component
TD68_19610	COG2814	Major facilitator Superfamily
TD68_19615	COG1309	transcriptional regulator
TD68_19620	COG0457	Tetratricopeptide repeat
TD68_19625	COG0778	Nitroreductase
TD68_19630	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
TD68_19635	COG0640	Transcriptional regulator
TD68_19640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_19645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TD68_19650	COG1012	belongs to the aldehyde dehydrogenase family
TD68_19655	COG4975	Glucose uptake
TD68_19660	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_19665	COG4549	nuclear export factor GLE1
TD68_19670	COG1276	copper resistance
TD68_19670	COG2372	response to copper ion
TD68_19675	COG1349	DNA-binding transcription factor activity
TD68_19685	COG2213	PTS system mannitol-specific
TD68_19690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_19695	COG0246	Mannitol dehydrogenase
TD68_19700	COG0412	Dienelactone hydrolase
TD68_19705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TD68_19715	COG0561	phosphatase activity
TD68_19720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TD68_19725	COG1914	H( )-stimulated, divalent metal cation uptake system
TD68_19730	COG4336	lyase activity
TD68_19735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TD68_19740	COG1984	allophanate hydrolase subunit 2
TD68_19745	COG1414	Transcriptional regulator
TD68_19750	COG2755	lipolytic protein G-D-S-L family
TD68_19760	COG2329	Antibiotic biosynthesis monooxygenase
TD68_19765	COG0768	penicillin binding
TD68_19770	COG4989	oxidoreductase activity
TD68_19775	COG3711	transcriptional antiterminator
TD68_19780	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_19785	COG2226	methyltransferase
TD68_19790	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_19795	COG1917	Cupin 2, conserved barrel domain protein
TD68_19800	COG3871	stress protein (general stress protein 26)
TD68_19815	COG2814	Major facilitator Superfamily
TD68_19830	COG1522	sequence-specific DNA binding
TD68_19835	COG0551	DNA topoisomerase type I activity
TD68_19835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD68_19840	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
TD68_19845	COG3706	GGDEF domain
TD68_19850	COG5298	Protein conserved in bacteria
TD68_19855	COG1215	transferase activity, transferring glycosyl groups
TD68_19865	COG0531	amino acid
TD68_19870	COG0494	nUDIX hydrolase
TD68_19875	COG0028	Belongs to the TPP enzyme family
TD68_19885	COG1914	H( )-stimulated, divalent metal cation uptake system
TD68_19890	COG2261	transglycosylase associated protein
TD68_19895	COG4876	unkown
TD68_19900	COG2217	Heavy metal translocating P-type atpase
TD68_19905	COG3729	General stress protein
TD68_19910	COG0662	Cupin 2, conserved barrel domain protein
TD68_19915	COG2329	Antibiotic biosynthesis monooxygenase
TD68_19920	COG3546	catalase activity
TD68_19925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TD68_19930	COG3290	protein histidine kinase activity
TD68_19935	COG4565	transcriptional regulatory protein
TD68_19940	COG1301	dicarboxylic acid transport
TD68_19945	COG0628	permease
TD68_19950	COG1131	(ABC) transporter
TD68_19955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_19965	COG1960	acyl-CoA dehydrogenase activity
TD68_19975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD68_19980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_19985	COG1181	Belongs to the D-alanine--D-alanine ligase family
TD68_19990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TD68_20000	COG0513	Belongs to the DEAD box helicase family
TD68_20005	COG3402	PFAM membrane-flanked domain
TD68_20010	COG3428	Bacterial PH domain
TD68_20015	COG0705	Rhomboid family
TD68_20020	COG0736	holo-[acyl-carrier-protein] synthase activity
TD68_20025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TD68_20030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD68_20035	COG0864	Transcriptional regulator
TD68_20040	COG2337	Toxic component of a toxin-antitoxin (TA) module
TD68_20045	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_20050	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_20055	COG2172	sigma factor antagonist activity
TD68_20060	COG2208	phosphoserine phosphatase activity
TD68_20065	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_20070	COG2172	sigma factor antagonist activity
TD68_20075	COG1191	sigma factor activity
TD68_20080	COG2208	phosphoserine phosphatase activity
TD68_20085	COG2183	response to ionizing radiation
TD68_20090	COG3091	SprT-like family
TD68_20130	COG0582	viral genome integration into host DNA
TD68_20135	COG2856	Zn peptidase
TD68_20140	COG1396	sequence-specific DNA binding
TD68_20170	COG1674	ftsk spoiiie
TD68_20175	COG2946	Replication initiation factor
TD68_20220	COG0433	COG0433 Predicted ATPase
TD68_20230	COG5644	endopeptidase inhibitor activity
TD68_20240	COG0791	NLP P60 protein
TD68_20240	COG0741	lytic transglycosylase activity
TD68_20260	COG0457	Tetratricopeptide repeat
TD68_20270	COG3239	Fatty acid desaturase
TD68_20275	COG1278	Cold shock
TD68_20280	COG1329	Transcriptional regulator
TD68_20285	COG1802	Transcriptional regulator
TD68_20290	COG0697	spore germination
TD68_20300	COG5444	nuclease activity
TD68_20305	COG2364	Membrane
TD68_20310	COG1846	Transcriptional regulator
TD68_20315	COG0456	acetyltransferase
TD68_20320	COG2808	Putative FMN-binding domain
TD68_20325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_20335	COG2814	Major facilitator Superfamily
TD68_20340	COG0697	spore germination
TD68_20345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_20350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_20360	COG0640	Transcriptional regulator
TD68_20365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TD68_20370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_20380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_20390	COG1846	Transcriptional regulator
TD68_20395	COG1033	growth of symbiont in host cell
TD68_20395	COG2409	Drug exporters of the RND superfamily
TD68_20400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_20400	COG3711	transcriptional antiterminator
TD68_20405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_20405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_20405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_20410	COG1482	cell wall glycoprotein biosynthetic process
TD68_20415	COG0697	spore germination
TD68_20420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_20425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_20430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TD68_20435	COG1522	sequence-specific DNA binding
TD68_20450	COG0596	Alpha beta hydrolase
TD68_20465	COG2602	Beta-lactamase
TD68_20475	COG2814	Major facilitator Superfamily
TD68_20485	COG3858	chitin binding
TD68_20485	COG1388	LysM domain
TD68_20490	COG1819	glycosyl