locus-tag	class	description
K7T73_00010	COG0592	DNA-directed DNA polymerase activity
K7T73_00015	COG2501	S4 domain
K7T73_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K7T73_00025	COG0187	DNA topoisomerase II activity
K7T73_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K7T73_00035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K7T73_00065	COG0386	Belongs to the glutathione peroxidase family
K7T73_00075	COG0517	IMP dehydrogenase activity
K7T73_00075	COG0516	GMP reductase activity
K7T73_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
K7T73_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K7T73_00105	COG1335	isochorismatase
K7T73_00110	COG0590	tRNA wobble adenosine to inosine editing
K7T73_00120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K7T73_00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K7T73_00130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K7T73_00175	COG1982	Orn Lys Arg decarboxylase major
K7T73_00180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K7T73_00185	COG3870	Protein conserved in bacteria
K7T73_00190	COG1728	Protein conserved in bacteria
K7T73_00195	COG0470	DNA polymerase III
K7T73_00200	COG1774	PSP1 C-terminal conserved region
K7T73_00205	COG4467	Involved in initiation control of chromosome replication
K7T73_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K7T73_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K7T73_00225	COG2002	toxin-antitoxin pair type II binding
K7T73_00235	COG0084	hydrolase, TatD family'
K7T73_00245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K7T73_00255	COG4466	Protein conserved in bacteria
K7T73_00265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K7T73_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K7T73_00275	COG0251	oxidation-reduction process
K7T73_00280	COG2088	sporulation resulting in formation of a cellular spore
K7T73_00285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K7T73_00295	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K7T73_00310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K7T73_00315	COG2002	toxin-antitoxin pair type II binding
K7T73_00320	COG2244	polysaccharide biosynthetic process
K7T73_00325	COG3956	TIGRFAM MazG family protein
K7T73_00330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K7T73_00350	COG1098	S1 RNA binding domain
K7T73_00365	COG2208	phosphoserine phosphatase activity
K7T73_00370	COG2304	oxidoreductase activity
K7T73_00375	COG0515	serine threonine protein kinase
K7T73_00380	COG0037	tRNA processing
K7T73_00385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K7T73_00390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K7T73_00395	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K7T73_00400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K7T73_00405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K7T73_00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K7T73_00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K7T73_00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K7T73_00425	COG1396	sequence-specific DNA binding
K7T73_00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K7T73_00520	COG3880	PFAM UvrB UvrC protein
K7T73_00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
K7T73_00530	COG0542	response to heat
K7T73_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K7T73_00540	COG4956	integral membrane protein (PIN domain superfamily)
K7T73_00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K7T73_00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K7T73_00560	COG1045	serine acetyltransferase
K7T73_00565	COG0215	cysteine-tRNA ligase activity
K7T73_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K7T73_00580	COG3688	RNA-binding protein containing a PIN domain
K7T73_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K7T73_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K7T73_00600	COG0250	Participates in transcription elongation, termination and antitermination
K7T73_00610	COG0081	regulation of translation
K7T73_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K7T73_00620	COG0222	ribosome binding
K7T73_00625	COG2813	Specifically methylates the guanine in position
K7T73_00630	COG0085	RNA polymerase activity
K7T73_00640	COG1358	cellular component organization or biogenesis
K7T73_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K7T73_00650	COG0049	tRNA binding
K7T73_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K7T73_00665	COG0051	transcription antitermination factor activity, RNA binding
K7T73_00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K7T73_00675	COG0088	Forms part of the polypeptide exit tunnel
K7T73_00680	COG0089	rRNA binding
K7T73_00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K7T73_00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K7T73_00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K7T73_00700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K7T73_00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K7T73_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
K7T73_00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K7T73_00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K7T73_00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K7T73_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K7T73_00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K7T73_00755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K7T73_00760	COG1841	ribosomal large subunit assembly
K7T73_00770	COG0201	protein transport
K7T73_00775	COG0563	adenylate kinase activity
K7T73_00780	COG0024	Methionine aminopeptidase
K7T73_00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K7T73_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K7T73_00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K7T73_00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K7T73_00805	COG0202	RNA polymerase activity
K7T73_00810	COG0203	ribosomal protein L17
K7T73_00820	COG1122	ATPase activity
K7T73_00825	COG1122	ATPase activity
K7T73_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K7T73_00835	COG0101	tRNA pseudouridine synthase activity
K7T73_00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K7T73_00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K7T73_00870	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_00875	COG0489	protein tyrosine kinase activity
K7T73_00885	COG2194	sulfuric ester hydrolase activity
K7T73_00890	COG0726	polysaccharide deacetylase
K7T73_00965	COG1595	DNA-templated transcription, initiation
K7T73_00970	COG5662	AntiSigma factor
K7T73_00975	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K7T73_00985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K7T73_00990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K7T73_01005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K7T73_01025	COG0456	acetyltransferase
K7T73_01045	COG1522	sequence-specific DNA binding
K7T73_01055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
K7T73_01100	COG2818	Glycosylase
K7T73_01115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7T73_01120	COG1404	Belongs to the peptidase S8 family
K7T73_01140	COG4221	oxidoreductase activity
K7T73_01145	COG2814	Major facilitator Superfamily
K7T73_01150	COG0745	RESPONSE REGULATOR receiver
K7T73_01165	COG0697	spore germination
K7T73_01170	COG0697	spore germination
K7T73_01175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_01190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K7T73_01195	COG4149	molybdate abc transporter
K7T73_01200	COG0725	ABC transporter, periplasmic molybdate-binding protein
K7T73_01210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K7T73_01215	COG1228	amidohydrolase
K7T73_01245	COG2986	histidine ammonia-lyase
K7T73_01260	COG3695	enzyme binding
K7T73_01265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K7T73_01280	COG2124	cytochrome p450
K7T73_01285	COG1054	Belongs to the UPF0176 family
K7T73_01290	COG2304	oxidoreductase activity
K7T73_01295	COG0789	Transcriptional regulator
K7T73_01300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K7T73_01305	COG1609	Transcriptional regulator
K7T73_01310	COG2814	Major facilitator Superfamily
K7T73_01315	COG0655	NAD(P)H dehydrogenase (quinone) activity
K7T73_01330	COG0840	transmembrane signaling receptor activity
K7T73_01340	COG2076	Multidrug Resistance protein
K7T73_01345	COG2076	Multidrug Resistance protein
K7T73_01355	COG2112	serine threonine protein kinase
K7T73_01370	COG1695	Transcriptional regulator
K7T73_01390	COG3226	Transcriptional regulator
K7T73_01400	COG3852	Histidine kinase
K7T73_01405	COG2204	response regulator
K7T73_01410	COG2358	TRAP transporter, solute receptor (TAXI family
K7T73_01435	COG1227	inorganic diphosphatase activity
K7T73_01440	COG3104	oligopeptide transport
K7T73_01445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K7T73_01460	COG0579	oxidoreductase
K7T73_01475	COG0531	amino acid
K7T73_01480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K7T73_01495	COG3290	protein histidine kinase activity
K7T73_01495	COG3829	transcription factor binding
K7T73_01500	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_01510	COG2076	Multidrug Resistance protein
K7T73_01515	COG2076	Multidrug Resistance protein
K7T73_01520	COG1309	transcriptional regulator
K7T73_01535	COG1176	ABC-type spermidine putrescine transport system, permease component I
K7T73_01545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K7T73_01565	COG4585	Histidine kinase
K7T73_01570	COG2197	response regulator
K7T73_01575	COG0436	Aminotransferase
K7T73_01585	COG3835	regulator
K7T73_01590	COG0028	Belongs to the TPP enzyme family
K7T73_01620	COG1011	Hydrolase
K7T73_01635	COG1597	lipid kinase activity
K7T73_01640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7T73_01650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_01655	COG3835	regulator
K7T73_01660	COG0277	FAD linked oxidase domain protein
K7T73_01670	COG2070	2-Nitropropane dioxygenase
K7T73_01675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K7T73_01680	COG1823	symporter activity
K7T73_01690	COG1238	metal cluster binding
K7T73_01695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K7T73_01700	COG0586	Pfam SNARE associated Golgi protein
K7T73_01710	COG1253	flavin adenine dinucleotide binding
K7T73_01715	COG2239	Acts as a magnesium transporter
K7T73_01725	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
K7T73_01730	COG1181	Belongs to the D-alanine--D-alanine ligase family
K7T73_01735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K7T73_01745	COG0513	Belongs to the DEAD box helicase family
K7T73_01750	COG3402	PFAM membrane-flanked domain
K7T73_01755	COG3428	Bacterial PH domain
K7T73_01760	COG0736	holo-[acyl-carrier-protein] synthase activity
K7T73_01765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K7T73_01775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K7T73_01780	COG0864	Transcriptional regulator
K7T73_01785	COG2337	Toxic component of a toxin-antitoxin (TA) module
K7T73_01790	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_01795	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_01800	COG2172	sigma factor antagonist activity
K7T73_01805	COG2208	phosphoserine phosphatase activity
K7T73_01810	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_01815	COG2172	sigma factor antagonist activity
K7T73_01820	COG1191	sigma factor activity
K7T73_01825	COG2208	phosphoserine phosphatase activity
K7T73_01830	COG2183	response to ionizing radiation
K7T73_01835	COG3091	SprT-like family
K7T73_01915	COG0802	atpase or kinase
K7T73_01920	COG1214	PFAM Peptidase M22, glycoprotease
K7T73_01925	COG0456	acetyltransferase
K7T73_01935	COG0488	(ABC) transporter
K7T73_01940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K7T73_01945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K7T73_01950	COG0805	protein transport
K7T73_01960	COG1266	CAAX protease self-immunity
K7T73_01965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K7T73_01970	COG0459	protein refolding
K7T73_02000	COG0459	protein refolding
K7T73_02015	COG2814	Major facilitator Superfamily
K7T73_02040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K7T73_02040	COG1918	ferrous iron import across plasma membrane
K7T73_02045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K7T73_02050	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K7T73_02065	COG0655	NAD(P)H dehydrogenase (quinone) activity
K7T73_02120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K7T73_02125	COG0477	Major facilitator Superfamily
K7T73_02130	COG0531	amino acid
K7T73_02140	COG1757	Na H antiporter
K7T73_02150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_02160	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_02165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K7T73_02165	COG3153	acetyltransferase
K7T73_02170	COG3829	transcription factor binding
K7T73_02175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K7T73_02185	COG1657	PFAM Prenyltransferase squalene oxidase
K7T73_02195	COG1368	sulfuric ester hydrolase activity
K7T73_02205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K7T73_02215	COG1115	amino acid carrier protein
K7T73_02220	COG4187	Peptidase family M20/M25/M40
K7T73_02225	COG0519	Catalyzes the synthesis of GMP from XMP
K7T73_02225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K7T73_02230	COG2252	PERMEase
K7T73_02250	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
K7T73_02260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K7T73_02265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K7T73_02270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K7T73_02280	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K7T73_02285	COG0047	phosphoribosylformylglycinamidine synthase activity
K7T73_02290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K7T73_02295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K7T73_02300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K7T73_02305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K7T73_02310	COG0138	bifunctional purine biosynthesis protein purh
K7T73_02315	COG0151	Belongs to the GarS family
K7T73_02325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K7T73_02330	COG1470	cell adhesion involved in biofilm formation
K7T73_02335	COG4496	protein, YerC YecD
K7T73_02340	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
K7T73_02345	COG0210	DNA helicase
K7T73_02355	COG4851	CamS sex pheromone cAM373 precursor
K7T73_02360	COG1725	Transcriptional regulator
K7T73_02365	COG1131	(ABC) transporter
K7T73_02375	COG2224	Isocitrate lyase
K7T73_02380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K7T73_02385	COG0154	amidase activity
K7T73_02390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K7T73_02400	COG1704	LemA family
K7T73_02415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K7T73_02420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K7T73_02425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K7T73_02440	COG1597	lipid kinase activity
K7T73_02450	COG2814	Major facilitator Superfamily
K7T73_02455	COG1132	(ABC) transporter
K7T73_02460	COG1132	(ABC) transporter
K7T73_02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K7T73_02470	COG1309	transcriptional regulator
K7T73_02475	COG2814	Major facilitator Superfamily
K7T73_02505	COG2368	4-hydroxyphenylacetate
K7T73_02515	COG1131	(ABC) transporter
K7T73_02540	COG2814	Major facilitator Superfamily
K7T73_02590	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_02595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K7T73_02595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K7T73_02600	COG2391	methyltransferase activity
K7T73_02605	COG0243	molybdopterin cofactor binding
K7T73_02610	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
K7T73_02615	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
K7T73_02620	COG1850	ribulose-bisphosphate carboxylase activity
K7T73_02625	COG0235	Class ii aldolase
K7T73_02640	COG1129	ABC transporter
K7T73_02645	COG1172	Belongs to the binding-protein-dependent transport system permease family
K7T73_02655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K7T73_02660	COG2066	Belongs to the glutaminase family
K7T73_02690	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K7T73_02695	COG0772	Belongs to the SEDS family
K7T73_02710	COG1278	Cold shock
K7T73_02715	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_02725	COG0604	alcohol dehydrogenase
K7T73_02730	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K7T73_02735	COG2234	aminopeptidase activity
K7T73_02740	COG0833	amino acid
K7T73_02760	COG4187	Peptidase family M20/M25/M40
K7T73_02765	COG2814	Major facilitator Superfamily
K7T73_02785	COG2508	Transcriptional regulator
K7T73_02790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7T73_02800	COG0506	proline dehydrogenase activity
K7T73_02810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K7T73_02815	COG0805	protein transport
K7T73_02820	COG4294	response to UV
K7T73_02830	COG0514	ATP-dependent DNA helicase (RecQ)
K7T73_02850	COG0697	spore germination
K7T73_02870	COG0513	Belongs to the DEAD box helicase family
K7T73_02875	COG2208	phosphoserine phosphatase activity
K7T73_02885	COG0488	(ABC) transporter
K7T73_02890	COG1253	flavin adenine dinucleotide binding
K7T73_02895	COG0791	NLP P60 protein
K7T73_02895	COG1388	LysM domain
K7T73_02905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K7T73_02905	COG0551	DNA topoisomerase type I activity
K7T73_02915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K7T73_02920	COG0436	Aminotransferase
K7T73_02930	COG2746	aminoglycoside 3-N-acetyltransferase activity
K7T73_02935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K7T73_02940	COG0512	Glutamine amidotransferase of anthranilate synthase
K7T73_02945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K7T73_02950	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
K7T73_02970	COG1268	BioY protein
K7T73_02975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K7T73_02980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7T73_02990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K7T73_02995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_03000	COG1120	ATPase activity
K7T73_03005	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
K7T73_03010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K7T73_03020	COG1492	cobalamin metabolic process
K7T73_03025	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K7T73_03040	COG2096	Adenosyltransferase
K7T73_03055	COG0288	reversible hydration of carbon dioxide
K7T73_03090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K7T73_03095	COG1278	Cold shock
K7T73_03100	COG1388	LysM domain
K7T73_03100	COG0791	NLP P60 protein
K7T73_03110	COG2755	lipolytic protein G-D-S-L family
K7T73_03115	COG1410	methionine synthase
K7T73_03115	COG0646	methionine synthase
K7T73_03120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K7T73_03120	COG0646	methionine synthase
K7T73_03130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K7T73_03135	COG1077	Cell shape determining protein MreB Mrl
K7T73_03140	COG1607	acyl-coa hydrolase
K7T73_03145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K7T73_03150	COG0583	DNA-binding transcription factor activity
K7T73_03155	COG2309	aminopeptidase activity
K7T73_03160	COG1959	2 iron, 2 sulfur cluster binding
K7T73_03175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K7T73_03180	COG1360	Flagellar Motor Protein
K7T73_03185	COG1115	amino acid carrier protein
K7T73_03190	COG0693	protein deglycase activity
K7T73_03195	COG4840	Belongs to the UPF0435 family
K7T73_03200	COG1115	amino acid carrier protein
K7T73_03210	COG1295	ribonuclease BN
K7T73_03215	COG2217	Heavy metal translocating P-type atpase
K7T73_03225	COG0387	Pfam Sodium calcium exchanger
K7T73_03245	COG1575	Belongs to the MenA family. Type 1 subfamily
K7T73_03255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K7T73_03265	COG2233	PERMEase
K7T73_03270	COG1090	epimerase
K7T73_03280	COG0300	oxidoreductase activity
K7T73_03295	COG1988	membrane-bound metal-dependent
K7T73_03300	COG1194	a g-specific adenine glycosylase
K7T73_03305	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_03320	COG1132	(ABC) transporter
K7T73_03325	COG0444	Belongs to the ABC transporter superfamily
K7T73_03330	COG4608	Belongs to the ABC transporter superfamily
K7T73_03335	COG0747	negative chemotaxis
K7T73_03340	COG0601	transmembrane transport
K7T73_03345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7T73_03350	COG4129	membrane
K7T73_03355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K7T73_03365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K7T73_03370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K7T73_03375	COG0735	belongs to the Fur family
K7T73_03495	COG0582	viral genome integration into host DNA
K7T73_03505	COG1674	ftsk spoiiie
K7T73_03520	COG1192	Involved in chromosome partitioning
K7T73_03540	COG0577	efflux transmembrane transporter activity
K7T73_03545	COG1136	(ABC) transporter
K7T73_03550	COG2205	protein histidine kinase activity
K7T73_03555	COG0745	RESPONSE REGULATOR receiver
K7T73_03590	COG2766	serine protein kinase
K7T73_03595	COG2718	Belongs to the UPF0229 family
K7T73_03605	COG1063	alcohol dehydrogenase
K7T73_03610	COG2252	PERMEase
K7T73_03615	COG0306	phosphate transporter
K7T73_03620	COG1392	Phosphate transport regulator
K7T73_03625	COG0656	L-ascorbic acid biosynthetic process
K7T73_03630	COG0564	pseudouridine synthase activity
K7T73_03640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_03655	COG2719	SpoVR family
K7T73_03665	COG2217	Heavy metal translocating P-type atpase
K7T73_03670	COG2252	PERMEase
K7T73_03680	COG0640	Transcriptional regulator
K7T73_03685	COG1301	dicarboxylic acid transport
K7T73_03690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K7T73_03695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7T73_03695	COG4499	WXG100 protein secretion system (Wss), protein YukC
K7T73_03700	COG0129	dihydroxy-acid dehydratase activity
K7T73_03705	COG0028	Belongs to the TPP enzyme family
K7T73_03710	COG0440	acetolactate synthase activity
K7T73_03715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K7T73_03720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K7T73_03730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K7T73_03735	COG0066	3-isopropylmalate dehydratase activity
K7T73_03750	COG1937	Protein conserved in bacteria
K7T73_03765	COG4399	Belongs to the UPF0754 family
K7T73_03775	COG0561	phosphatase activity
K7T73_03780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K7T73_03790	COG4152	abc transporter atp-binding protein
K7T73_03795	COG1668	transmembrane transport
K7T73_03800	COG3481	metal-dependent phosphohydrolase, HD sub domain
K7T73_03810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K7T73_03825	COG1846	Transcriptional regulator
K7T73_03845	COG0537	adenosine 5'-monophosphoramidase activity
K7T73_03850	COG1131	(ABC) transporter
K7T73_03855	COG4473	ABC transporter
K7T73_03860	COG2329	Antibiotic biosynthesis monooxygenase
K7T73_03870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K7T73_03875	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K7T73_03900	COG1309	transcriptional regulator
K7T73_03905	COG1511	domain protein
K7T73_03915	COG1234	tRNA 3'-trailer cleavage
K7T73_03920	COG0095	Lipoate-protein ligase
K7T73_03925	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_03930	COG0501	Belongs to the peptidase M48B family
K7T73_03935	COG5582	Belongs to the UPF0302 family
K7T73_03940	COG0398	Pfam SNARE associated Golgi protein
K7T73_03945	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
K7T73_03950	COG1074	ATP-dependent DNA helicase activity
K7T73_03955	COG2311	Membrane
K7T73_03960	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7T73_03975	COG0366	Alpha amylase catalytic
K7T73_03975	COG1874	Beta-galactosidase
K7T73_03980	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_03985	COG1666	GTP binding
K7T73_03990	COG1307	EDD domain protein, DegV family
K7T73_03995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_04000	COG0561	phosphatase activity
K7T73_04005	COG2151	metal-sulfur cluster biosynthetic enzyme
K7T73_04025	COG1744	ABC transporter substrate-binding protein PnrA-like
K7T73_04035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K7T73_04040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K7T73_04055	COG0180	Tryptophanyl-tRNA synthetase
K7T73_04060	COG4166	transmembrane transport
K7T73_04065	COG0601	transmembrane transport
K7T73_04070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7T73_04075	COG0444	Belongs to the ABC transporter superfamily
K7T73_04080	COG4608	Belongs to the ABC transporter superfamily
K7T73_04085	COG0456	acetyltransferase
K7T73_04090	COG1393	Belongs to the ArsC family
K7T73_04095	COG4862	establishment of competence for transformation
K7T73_04100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K7T73_04105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K7T73_04110	COG1136	(ABC) transporter
K7T73_04115	COG0577	efflux transmembrane transporter activity
K7T73_04125	COG1164	Oligoendopeptidase f
K7T73_04135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K7T73_04140	COG2346	COG2346, Truncated hemoglobins
K7T73_04145	COG0741	lytic transglycosylase activity
K7T73_04150	COG4116	CYTH
K7T73_04160	COG2357	RelA SpoT domain protein
K7T73_04170	COG0564	pseudouridine synthase activity
K7T73_04180	COG0475	glutathione-regulated potassium exporter activity
K7T73_04180	COG0569	domain protein
K7T73_04185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K7T73_04235	COG2153	protein acetylation
K7T73_04240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K7T73_04245	COG2382	esterase
K7T73_04300	COG0582	viral genome integration into host DNA
K7T73_04325	COG0358	DNA primase activity
K7T73_04405	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_04420	COG1120	ATPase activity
K7T73_04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_04430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_04435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K7T73_04440	COG2822	iron ion transport
K7T73_04445	COG2837	iron assimilation
K7T73_04450	COG0672	)-iron permease
K7T73_04460	COG2124	cytochrome p450
K7T73_04465	COG1309	transcriptional regulator
K7T73_04485	COG1960	acyl-CoA dehydrogenase activity
K7T73_04490	COG3383	formate dehydrogenase (NAD+) activity
K7T73_04495	COG2427	Protein of unknown function (DUF1641)
K7T73_04500	COG5566	PFAM Mor transcription activator
K7T73_04510	COG0443	Heat shock 70 kDa protein
K7T73_04525	COG3192	ethanolamine utilization protein
K7T73_04535	COG0840	transmembrane signaling receptor activity
K7T73_04545	COG1309	transcriptional regulator
K7T73_04555	COG0577	efflux transmembrane transporter activity
K7T73_04555	COG1136	(ABC) transporter
K7T73_04570	COG0493	'glutamate synthase
K7T73_04600	COG1119	ATPase activity
K7T73_04605	COG2427	Protein of unknown function (DUF1641)
K7T73_04610	COG3383	formate dehydrogenase (NAD+) activity
K7T73_04615	COG5609	conserved protein (DUF2294)
K7T73_04620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K7T73_04625	COG0069	glutamate synthase activity
K7T73_04630	COG1525	nuclease
K7T73_04645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K7T73_04650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K7T73_04650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K7T73_04655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K7T73_04655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K7T73_04660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K7T73_04685	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_04695	COG3424	synthase
K7T73_04700	COG1755	Isoprenylcysteine carboxyl methyltransferase
K7T73_04710	COG3773	Cell wall hydrolase
K7T73_04720	COG2508	Transcriptional regulator
K7T73_04725	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_04730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7T73_04735	COG0477	Major facilitator Superfamily
K7T73_04760	COG0174	glutamine synthetase
K7T73_04765	COG0367	asparagine synthase
K7T73_04770	COG1473	amidohydrolase
K7T73_04775	COG1757	Na H antiporter
K7T73_04795	COG0584	glycerophosphoryl diester phosphodiesterase
K7T73_04810	COG0196	riboflavin kinase activity
K7T73_04815	COG3485	protocatechuate 3,4-dioxygenase
K7T73_04830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K7T73_04835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K7T73_04840	COG4948	Mandelate Racemase Muconate Lactonizing
K7T73_04850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K7T73_04855	COG1595	DNA-templated transcription, initiation
K7T73_04890	COG0840	transmembrane signaling receptor activity
K7T73_04895	COG1937	Protein conserved in bacteria
K7T73_04900	COG2608	mercury ion transmembrane transporter activity
K7T73_04905	COG2217	Heavy metal translocating P-type atpase
K7T73_04915	COG3011	Protein conserved in bacteria
K7T73_04920	COG2032	superoxide dismutase activity
K7T73_04925	COG1278	Cold shock
K7T73_04935	COG0322	excinuclease ABC activity
K7T73_04940	COG2404	hydrolase activity, acting on ester bonds
K7T73_04945	COG4294	response to UV
K7T73_04975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K7T73_04980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K7T73_04985	COG0765	amino acid transport
K7T73_05015	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K7T73_05025	COG0071	Belongs to the small heat shock protein (HSP20) family
K7T73_05045	COG0494	nUDIX hydrolase
K7T73_05050	COG1335	isochorismatase
K7T73_05055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K7T73_05060	COG0626	cystathionine gamma-synthase activity
K7T73_05070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K7T73_05085	COG1737	Transcriptional regulator
K7T73_05095	COG4948	Mandelate Racemase Muconate Lactonizing
K7T73_05100	COG3949	Membrane
K7T73_05105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K7T73_05120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7T73_05125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K7T73_05130	COG1116	anion transmembrane transporter activity
K7T73_05135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K7T73_05140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K7T73_05145	COG1587	Uroporphyrinogen-III synthase
K7T73_05150	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
K7T73_05155	COG0351	phosphomethylpyrimidine kinase
K7T73_05165	COG5002	protein histidine kinase activity
K7T73_05170	COG3361	conserved protein (COG2071)
K7T73_05175	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K7T73_05195	COG2169	Transcriptional regulator
K7T73_05200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K7T73_05205	COG1414	Transcriptional regulator
K7T73_05210	COG2814	Major facilitator Superfamily
K7T73_05225	COG0281	malic enzyme
K7T73_05240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K7T73_05245	COG0626	cystathionine gamma-synthase activity
K7T73_05250	COG0626	cystathionine gamma-synthase activity
K7T73_05265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K7T73_05275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K7T73_05280	COG1757	Na H antiporter
K7T73_05290	COG0861	Integral membrane protein TerC family
K7T73_05295	COG1388	LysM domain
K7T73_05295	COG0791	NLP P60 protein
K7T73_05305	COG3594	Acyltransferase
K7T73_05315	COG3852	Histidine kinase
K7T73_05320	COG0737	Belongs to the 5'-nucleotidase family
K7T73_05330	COG0542	response to heat
K7T73_05335	COG3949	Membrane
K7T73_05345	COG4873	Protein conserved in bacteria
K7T73_05355	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_05360	COG2084	Dehydrogenase
K7T73_05365	COG0436	Aminotransferase
K7T73_05370	COG0598	Magnesium transport protein CorA
K7T73_05375	COG0784	Response regulator, receiver
K7T73_05375	COG0835	chemotaxis
K7T73_05385	COG1408	metallophosphoesterase
K7T73_05395	COG4703	Protein of unknown function (DUF1797)
K7T73_05400	COG0517	IMP dehydrogenase activity
K7T73_05405	COG0477	Major facilitator Superfamily
K7T73_05410	COG0583	DNA-binding transcription factor activity
K7T73_05415	COG2171	N-acyltransferase activity
K7T73_05420	COG1473	amidohydrolase
K7T73_05425	COG0450	alkyl hydroperoxide reductase
K7T73_05430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_05435	COG1271	oxidase subunit
K7T73_05440	COG1294	oxidase, subunit
K7T73_05445	COG0569	domain protein
K7T73_05450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K7T73_05460	COG0561	phosphatase activity
K7T73_05465	COG0242	peptide deformylase activity
K7T73_05475	COG0022	dehydrogenase e1 component
K7T73_05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7T73_05505	COG1982	Orn Lys Arg decarboxylase major
K7T73_05510	COG4476	Belongs to the UPF0223 family
K7T73_05515	COG4493	Belongs to the UPF0637 family
K7T73_05525	COG0483	inositol monophosphate 1-phosphatase activity
K7T73_05535	COG1217	gtp-binding protein TYPA
K7T73_05545	COG4896	Protein conserved in bacteria
K7T73_05560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K7T73_05565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K7T73_05575	COG0772	Belongs to the SEDS family
K7T73_05580	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K7T73_05590	COG0109	protoheme IX farnesyltransferase activity
K7T73_05615	COG3336	cytochrome c oxidase
K7T73_05635	COG2340	Cysteine-rich secretory protein family
K7T73_05660	COG3679	Belongs to the UPF0342 family
K7T73_05665	COG4471	UPF0298 protein
K7T73_05680	COG0742	ribosomal rna small subunit methyltransferase
K7T73_05685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K7T73_05690	COG3314	Sporulation integral membrane protein YlbJ
K7T73_05695	COG1752	Esterase of the alpha-beta hydrolase superfamily
K7T73_05700	COG3480	Lon protease (S16) C-terminal proteolytic domain
K7T73_05705	COG1323	Belongs to the UPF0348 family
K7T73_05710	COG1399	metal-binding, possibly nucleic acid-binding protein
K7T73_05715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K7T73_05720	COG1024	Enoyl-CoA hydratase
K7T73_05725	COG0454	-acetyltransferase
K7T73_05730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K7T73_05735	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
K7T73_05750	COG0275	rRNA processing
K7T73_05755	COG4839	cell division protein FtsL
K7T73_05760	COG0768	penicillin binding
K7T73_05765	COG0768	penicillin binding
K7T73_05775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K7T73_05785	COG0772	Belongs to the SEDS family
K7T73_05790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K7T73_05795	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K7T73_05800	COG0849	cell division
K7T73_05805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K7T73_05815	COG1191	sigma factor activity
K7T73_05820	COG1191	sigma factor activity
K7T73_05825	COG1873	PFAM PRC-barrel domain
K7T73_05835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K7T73_05840	COG1799	cell septum assembly
K7T73_05845	COG0762	integral membrane protein
K7T73_05850	COG2302	S4 RNA-binding domain
K7T73_05855	COG3599	regulation of cell shape
K7T73_05865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K7T73_05870	COG0564	pseudouridine synthase activity
K7T73_05875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
K7T73_05880	COG0540	Belongs to the ATCase OTCase family
K7T73_05885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K7T73_05895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K7T73_05905	COG0167	dihydroorotate dehydrogenase activity
K7T73_05910	COG0284	orotidine-5'-phosphate decarboxylase activity
K7T73_05920	COG1293	RNA-binding protein homologous to eukaryotic snRNP
K7T73_05925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K7T73_05930	COG1561	YicC-like family, N-terminal region
K7T73_05935	COG2052	Domain of unknown function (DUF370)
K7T73_05940	COG0194	GDP metabolic process
K7T73_05950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K7T73_05955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K7T73_05965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K7T73_05970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K7T73_05970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K7T73_05975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K7T73_05980	COG0631	protein serine/threonine phosphatase activity
K7T73_05985	COG0515	serine threonine protein kinase
K7T73_05985	COG2815	serine threonine protein kinase
K7T73_05990	COG1162	GTPase activity
K7T73_05995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K7T73_06000	COG1564	THIamine pyrophosphokinase
K7T73_06015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K7T73_06020	COG1302	Protein conserved in bacteria
K7T73_06025	COG1461	Dihydroxyacetone kinase
K7T73_06030	COG1760	l-serine dehydratase
K7T73_06035	COG1760	l-serine dehydratase
K7T73_06040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K7T73_06045	COG1349	DNA-binding transcription factor activity
K7T73_06050	COG0416	fatty acid biosynthetic process
K7T73_06055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K7T73_06060	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_06065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K7T73_06070	COG0571	ribonuclease III activity
K7T73_06075	COG1196	nuclear chromosome segregation
K7T73_06080	COG0552	protein localization to endoplasmic reticulum
K7T73_06085	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
K7T73_06090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K7T73_06095	COG0228	four-way junction DNA binding
K7T73_06100	COG1837	Belongs to the UPF0109 family
K7T73_06110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K7T73_06115	COG0336	Belongs to the RNA methyltransferase TrmD family
K7T73_06120	COG0335	large ribosomal subunit rRNA binding
K7T73_06145	COG2257	FlhB HrpN YscU SpaS Family
K7T73_06155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K7T73_06160	COG0758	DNA mediated transformation
K7T73_06165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K7T73_06170	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K7T73_06175	COG4974	Belongs to the 'phage' integrase family
K7T73_06185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K7T73_06190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
K7T73_06195	COG1815	bacterial-type flagellum-dependent cell motility
K7T73_06200	COG1558	bacterial-type flagellum-dependent cell motility
K7T73_06205	COG1677	Flagellar hook-basal body complex protein FliE
K7T73_06210	COG1766	The M ring may be actively involved in energy transduction
K7T73_06215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K7T73_06225	COG1157	protein secretion by the type III secretion system
K7T73_06230	COG2882	bacterial-type flagellum organization
K7T73_06245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K7T73_06250	COG4786	Flagellar basal body rod
K7T73_06255	COG1582	Flagellar protein (FlbD)
K7T73_06260	COG1580	Controls the rotational direction of flagella during chemotaxis
K7T73_06265	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K7T73_06270	COG1776	CheC inhibitor of MCP methylation
K7T73_06270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K7T73_06275	COG2201	protein-glutamate methylesterase activity
K7T73_06280	COG3190	flagellar
K7T73_06285	COG1338	Plays a role in the flagellum-specific transport system
K7T73_06290	COG1987	bacterial-type flagellum assembly
K7T73_06295	COG1684	flagellar biosynthetic protein fliR
K7T73_06300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K7T73_06305	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K7T73_06310	COG1419	protein localization to endoplasmic reticulum
K7T73_06315	COG0455	bacterial-type flagellum organization
K7T73_06320	COG2201	protein-glutamate methylesterase activity
K7T73_06325	COG0643	Histidine kinase
K7T73_06325	COG2198	Histidine kinase
K7T73_06330	COG0835	chemotaxis
K7T73_06335	COG1776	CheC inhibitor of MCP methylation
K7T73_06345	COG1191	sigma factor activity
K7T73_06355	COG0052	Belongs to the universal ribosomal protein uS2 family
K7T73_06365	COG0528	UMP kinase activity
K7T73_06370	COG0233	cytoplasmic translational termination
K7T73_06375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K7T73_06380	COG4589	Belongs to the CDS family
K7T73_06385	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K7T73_06390	COG0750	zinc metalloprotease
K7T73_06395	COG0442	prolyl-tRNA aminoacylation
K7T73_06400	COG2176	DNA-directed DNA polymerase activity
K7T73_06405	COG0779	Required for maturation of 30S ribosomal subunits
K7T73_06410	COG0195	Participates in both transcription termination and antitermination
K7T73_06415	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K7T73_06420	COG1358	cellular component organization or biogenesis
K7T73_06430	COG1550	Protein conserved in bacteria
K7T73_06440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K7T73_06445	COG0196	riboflavin kinase activity
K7T73_06450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K7T73_06455	COG1185	polyribonucleotide nucleotidyltransferase activity
K7T73_06460	COG0726	polysaccharide deacetylase
K7T73_06465	COG0612	Peptidase, M16
K7T73_06470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K7T73_06475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K7T73_06480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K7T73_06485	COG0527	aspartate kinase activity
K7T73_06495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K7T73_06500	COG0740	serine-type endopeptidase activity
K7T73_06510	COG1674	ftsk spoiiie
K7T73_06510	COG4980	gas vesicle protein
K7T73_06515	COG2188	Transcriptional regulator
K7T73_06520	COG1744	ABC transporter substrate-binding protein PnrA-like
K7T73_06525	COG3845	ABC transporter
K7T73_06530	COG4603	Belongs to the binding-protein-dependent transport system permease family
K7T73_06535	COG1079	Belongs to the binding-protein-dependent transport system permease family
K7T73_06540	COG0612	Peptidase, M16
K7T73_06545	COG0612	Peptidase, M16
K7T73_06550	COG0300	oxidoreductase activity
K7T73_06565	COG1426	Protein conserved in bacteria
K7T73_06570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K7T73_06575	COG1058	Belongs to the CinA family
K7T73_06575	COG1546	Belongs to the CinA family
K7T73_06585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K7T73_06590	COG1418	mRNA catabolic process
K7T73_06595	COG1692	metallophosphoesterase
K7T73_06600	COG2359	stage V sporulation protein S
K7T73_06610	COG0674	pyruvate-flavodoxin oxidoreductase activity
K7T73_06610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K7T73_06615	COG1013	pyruvate-flavodoxin oxidoreductase activity
K7T73_06620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K7T73_06625	COG4550	Control of competence regulator ComK, YlbF/YmcA
K7T73_06635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K7T73_06645	COG1132	(ABC) transporter
K7T73_06655	COG0477	Major facilitator Superfamily
K7T73_06660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K7T73_06665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K7T73_06670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K7T73_06675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K7T73_06680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K7T73_06690	COG0464	growth
K7T73_06695	COG1309	transcriptional regulator
K7T73_06700	COG1960	acyl-CoA dehydrogenase activity
K7T73_06705	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_06710	COG0439	Biotin carboxylase
K7T73_06715	COG0511	ligase activity, forming carbon-carbon bonds
K7T73_06720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K7T73_06725	COG1024	Enoyl-CoA hydratase
K7T73_06730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7T73_06735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K7T73_06740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K7T73_06745	COG2860	membrane
K7T73_06750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K7T73_06755	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K7T73_06760	COG0789	Transcriptional regulator
K7T73_06765	COG0174	glutamine synthetase
K7T73_06795	COG1396	sequence-specific DNA binding
K7T73_06880	COG0464	growth
K7T73_06935	COG0662	Cupin 2, conserved barrel domain protein
K7T73_06960	COG0863	Belongs to the N(4) N(6)-methyltransferase family
K7T73_06975	COG1783	phage Terminase large subunit
K7T73_06980	COG5518	Phage portal protein
K7T73_06985	COG2369	cell adhesion
K7T73_07000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K7T73_07005	COG4653	Phage capsid family
K7T73_07055	COG3953	SLT domain
K7T73_07055	COG5280	Phage tail tape measure protein TP901
K7T73_07060	COG1652	LysM domain
K7T73_07065	COG4193	domain, Protein
K7T73_07075	COG3628	GPW Gp25 family protein
K7T73_07080	COG3299	homolog of phage Mu protein gp47
K7T73_07150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K7T73_07160	COG3844	kynureninase activity
K7T73_07165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K7T73_07170	COG1388	LysM domain
K7T73_07175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K7T73_07195	COG3763	UPF0154 protein
K7T73_07205	COG0785	Cytochrome C biogenesis protein
K7T73_07210	COG2201	protein-glutamate methylesterase activity
K7T73_07215	COG4846	Membrane protein involved in cytochrome C biogenesis
K7T73_07230	COG0419	ATPase involved in DNA repair
K7T73_07235	COG1999	signal sequence binding
K7T73_07245	COG2508	Transcriptional regulator
K7T73_07245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
K7T73_07250	COG0686	Belongs to the AlaDH PNT family
K7T73_07265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7T73_07270	COG3162	membrane
K7T73_07280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K7T73_07300	COG2855	membrane
K7T73_07305	COG0583	DNA-binding transcription factor activity
K7T73_07310	COG1609	Transcriptional regulator
K7T73_07315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7T73_07325	COG0531	amino acid
K7T73_07330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K7T73_07345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K7T73_07355	COG0551	DNA topoisomerase type I activity
K7T73_07355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K7T73_07365	COG0598	Magnesium transport protein CorA
K7T73_07370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K7T73_07385	COG0405	Gamma-glutamyltransferase
K7T73_07395	COG0824	Thioesterase
K7T73_07405	COG4841	protein insertion into membrane
K7T73_07410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K7T73_07415	COG2233	PERMEase
K7T73_07420	COG0745	RESPONSE REGULATOR receiver
K7T73_07425	COG2205	protein histidine kinase activity
K7T73_07430	COG1131	(ABC) transporter
K7T73_07440	COG1832	CoA-binding protein
K7T73_07445	COG0187	DNA topoisomerase II activity
K7T73_07450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K7T73_07455	COG1115	amino acid carrier protein
K7T73_07470	COG2022	thiamine diphosphate biosynthetic process
K7T73_07480	COG0352	thiamine-phosphate diphosphorylase activity
K7T73_07485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K7T73_07490	COG3284	Transcriptional regulator
K7T73_07505	COG0641	radical SAM
K7T73_07535	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_07545	COG5522	Integral membrane protein (intg_mem_TP0381)
K7T73_07550	COG0546	phosphoglycolate phosphatase activity
K7T73_07560	COG2814	Major facilitator Superfamily
K7T73_07580	COG2226	methyltransferase
K7T73_07595	COG5002	protein histidine kinase activity
K7T73_07600	COG0745	RESPONSE REGULATOR receiver
K7T73_07605	COG1473	amidohydrolase
K7T73_07610	COG0024	Methionine aminopeptidase
K7T73_07615	COG0803	Belongs to the bacterial solute-binding protein 9 family
K7T73_07620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_07620	COG0723	plastoquinol--plastocyanin reductase activity
K7T73_07630	COG1278	Cold shock
K7T73_07650	COG0109	protoheme IX farnesyltransferase activity
K7T73_07655	COG5002	protein histidine kinase activity
K7T73_07665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K7T73_07670	COG0671	phosphoesterase, PA-phosphatase related
K7T73_07700	COG1131	(ABC) transporter
K7T73_07710	COG0460	homoserine dehydrogenase
K7T73_07715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K7T73_07720	COG0083	homoserine kinase activity
K7T73_07725	COG2271	Major facilitator Superfamily
K7T73_07735	COG2030	dehydratase
K7T73_07755	COG1960	acyl-CoA dehydrogenase activity
K7T73_07760	COG1960	acyl-CoA dehydrogenase activity
K7T73_07765	COG1960	acyl-CoA dehydrogenase activity
K7T73_07770	COG1960	acyl-CoA dehydrogenase activity
K7T73_07775	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_07780	COG0183	Belongs to the thiolase family
K7T73_07790	COG1024	Enoyl-CoA hydratase
K7T73_07795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K7T73_07800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_07810	COG4145	pantothenate transmembrane transporter activity
K7T73_07815	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K7T73_07820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K7T73_07825	COG0512	Glutamine amidotransferase of anthranilate synthase
K7T73_07825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K7T73_07835	COG0135	phosphoribosylanthranilate isomerase activity
K7T73_07845	COG0159	tryptophan synthase activity
K7T73_07850	COG2210	Belongs to the sulfur carrier protein TusA family
K7T73_07860	COG0567	Dehydrogenase, E1 component
K7T73_07865	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7T73_07885	COG0714	Associated with various cellular activities
K7T73_07890	COG4548	von Willebrand factor, type A
K7T73_07895	COG1114	Component of the transport system for branched-chain amino acids
K7T73_07900	COG3853	Toxic anion resistance protein (TelA)
K7T73_07905	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
K7T73_07915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K7T73_07920	COG1380	Effector of murein hydrolase LrgA
K7T73_07925	COG1346	cytolysis
K7T73_07930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K7T73_07940	COG0436	Aminotransferase
K7T73_07945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K7T73_07955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K7T73_07965	COG2323	membrane
K7T73_08005	COG2223	nitrite transmembrane transporter activity
K7T73_08020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K7T73_08025	COG1476	TRANSCRIPTIONal
K7T73_08030	COG1272	protein, Hemolysin III
K7T73_08040	COG2388	GCN5-related N-acetyl-transferase
K7T73_08050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_08060	COG1994	Peptidase M50
K7T73_08065	COG0488	(ABC) transporter
K7T73_08075	COG3871	stress protein (general stress protein 26)
K7T73_08080	COG0175	sulfate reduction
K7T73_08085	COG2046	Belongs to the sulfate adenylyltransferase family
K7T73_08090	COG0529	Catalyzes the synthesis of activated sulfate
K7T73_08105	COG1648	precorrin-2 dehydrogenase activity
K7T73_08110	COG0730	response to heat
K7T73_08115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K7T73_08120	COG0367	asparagine synthase
K7T73_08165	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_08170	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7T73_08175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7T73_08185	COG0765	amino acid transport
K7T73_08190	COG1126	abc transporter atp-binding protein
K7T73_08195	COG4187	Peptidase family M20/M25/M40
K7T73_08200	COG0833	amino acid
K7T73_08205	COG2323	membrane
K7T73_08210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K7T73_08220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7T73_08245	COG0028	Belongs to the TPP enzyme family
K7T73_08250	COG0656	L-ascorbic acid biosynthetic process
K7T73_08265	COG1073	alpha beta
K7T73_08270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K7T73_08275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7T73_08280	COG1845	cytochrome c oxidase, subunit III
K7T73_08285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K7T73_08300	COG2197	response regulator
K7T73_08305	COG4585	Histidine kinase
K7T73_08310	COG3239	Fatty acid desaturase
K7T73_08315	COG2839	Protein conserved in bacteria
K7T73_08320	COG3663	DNA glycosylase
K7T73_08325	COG1834	amidinotransferase
K7T73_08345	COG0659	secondary active sulfate transmembrane transporter activity
K7T73_08350	COG0183	Belongs to the thiolase family
K7T73_08355	COG0412	Dienelactone hydrolase
K7T73_08365	COG4948	Mandelate Racemase Muconate Lactonizing
K7T73_08385	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K7T73_08390	COG3859	Proton-coupled thiamine transporter YuaJ
K7T73_08395	COG1376	ErfK ybiS ycfS ynhG family protein
K7T73_08405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7T73_08410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K7T73_08415	COG1174	glycine betaine transport
K7T73_08420	COG0517	IMP dehydrogenase activity
K7T73_08420	COG1125	glycine betaine transport
K7T73_08425	COG5002	protein histidine kinase activity
K7T73_08435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K7T73_08440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K7T73_08455	COG0535	radical SAM domain protein
K7T73_08460	COG0803	Belongs to the bacterial solute-binding protein 9 family
K7T73_08465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K7T73_08470	COG1121	(ABC) transporter
K7T73_08480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7T73_08485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_08495	COG0732	type I restriction modification DNA specificity domain
K7T73_08510	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
K7T73_08530	COG0582	viral genome integration into host DNA
K7T73_08605	COG2211	Major facilitator Superfamily
K7T73_08615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K7T73_08630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_08635	COG1279	arginine transmembrane transporter activity
K7T73_08680	COG0584	glycerophosphoryl diester phosphodiesterase
K7T73_08690	COG2211	Major facilitator Superfamily
K7T73_08695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7T73_08710	COG1388	LysM domain
K7T73_08715	COG0745	RESPONSE REGULATOR receiver
K7T73_08720	COG5002	protein histidine kinase activity
K7T73_08725	COG2259	Doxx family
K7T73_08730	COG3384	dioxygenase
K7T73_08745	COG5505	Protein of unknown function (DUF819)
K7T73_08755	COG0346	lactoylglutathione lyase activity
K7T73_08790	COG0427	acetyl-CoA hydrolase
K7T73_08795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7T73_08800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7T73_08830	COG3180	Ammonia monooxygenase
K7T73_08835	COG0583	DNA-binding transcription factor activity
K7T73_08845	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K7T73_08850	COG3300	MHYT domain
K7T73_08850	COG5001	Diguanylate cyclase
K7T73_08855	COG0840	transmembrane signaling receptor activity
K7T73_08865	COG0521	Mo-molybdopterin cofactor biosynthetic process
K7T73_08870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K7T73_08875	COG0746	molybdenum cofactor guanylyltransferase activity
K7T73_08880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K7T73_08885	COG0314	molybdopterin synthase activity
K7T73_08890	COG0315	cyclic pyranopterin monophosphate synthase activity
K7T73_08895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K7T73_08900	COG1763	Mo-molybdopterin cofactor biosynthetic process
K7T73_08905	COG0303	'Molybdopterin
K7T73_08910	COG0604	alcohol dehydrogenase
K7T73_08925	COG2234	aminopeptidase activity
K7T73_08945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K7T73_08950	COG1671	Belongs to the UPF0178 family
K7T73_08955	COG5002	protein histidine kinase activity
K7T73_08965	COG0351	phosphomethylpyrimidine kinase
K7T73_08980	COG0726	polysaccharide deacetylase
K7T73_08995	COG5434	Belongs to the glycosyl hydrolase 28 family
K7T73_09000	COG0463	Glycosyl transferase, family 2
K7T73_09010	COG4485	Bacterial membrane protein, YfhO
K7T73_09025	COG0791	NLP P60 protein
K7T73_09025	COG1388	LysM domain
K7T73_09085	COG2824	Alkylphosphonate utilization operon protein PhnA
K7T73_09125	COG4682	membrane
K7T73_09140	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
K7T73_09145	COG0310	cobalt ion transport
K7T73_09150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K7T73_09150	COG1587	Uroporphyrinogen-III synthase
K7T73_09155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K7T73_09155	COG1648	precorrin-2 dehydrogenase activity
K7T73_09220	COG2226	methyltransferase
K7T73_09225	COG1268	BioY protein
K7T73_09235	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K7T73_09235	COG3264	Mechanosensitive ion channel
K7T73_09245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K7T73_09255	COG0583	DNA-binding transcription factor activity
K7T73_09265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K7T73_09270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K7T73_09270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K7T73_09275	COG0307	riboflavin synthase, alpha
K7T73_09280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K7T73_09280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K7T73_09305	COG0714	Associated with various cellular activities
K7T73_09310	COG1393	Belongs to the ArsC family
K7T73_09335	COG2801	Transposase and inactivated derivatives
K7T73_09360	COG0358	DNA primase activity
K7T73_09390	COG0629	single-stranded DNA binding
K7T73_09415	COG0789	Transcriptional regulator
K7T73_09425	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_09470	COG0488	(ABC) transporter
K7T73_09515	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
K7T73_09520	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
K7T73_09550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K7T73_09570	COG1396	sequence-specific DNA binding
K7T73_09575	COG0640	Transcriptional regulator
K7T73_09580	COG0346	lactoylglutathione lyase activity
K7T73_09585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K7T73_09590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K7T73_09640	COG1185	polyribonucleotide nucleotidyltransferase activity
K7T73_09640	COG0539	negative regulation of cytoplasmic translation
K7T73_09640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K7T73_09665	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_09705	COG0741	lytic transglycosylase activity
K7T73_09705	COG0791	NLP P60 protein
K7T73_09775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K7T73_09790	COG1396	sequence-specific DNA binding
K7T73_09850	COG1396	sequence-specific DNA binding
K7T73_09915	COG2856	Zn peptidase
K7T73_09925	COG1131	(ABC) transporter
K7T73_09940	COG0535	radical SAM domain protein
K7T73_09955	COG4974	Belongs to the 'phage' integrase family
K7T73_10005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K7T73_10010	COG1131	(ABC) transporter
K7T73_10025	COG1595	DNA-templated transcription, initiation
K7T73_10055	COG3239	Fatty acid desaturase
K7T73_10060	COG1278	Cold shock
K7T73_10070	COG1329	Transcriptional regulator
K7T73_10095	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_10110	COG2814	Major facilitator Superfamily
K7T73_10115	COG1114	Component of the transport system for branched-chain amino acids
K7T73_10140	COG1131	(ABC) transporter
K7T73_10155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K7T73_10165	COG1476	TRANSCRIPTIONal
K7T73_10175	COG4106	trans-aconitate 2-methyltransferase activity
K7T73_10205	COG0842	Transport permease protein
K7T73_10210	COG1131	(ABC) transporter
K7T73_10230	COG1131	(ABC) transporter
K7T73_10255	COG1361	Conserved repeat domain
K7T73_10265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K7T73_10270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K7T73_10275	COG0640	Transcriptional regulator
K7T73_10280	COG1733	regulation of RNA biosynthetic process
K7T73_10290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K7T73_10300	COG2318	DinB family
K7T73_10325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_10330	COG2808	Putative FMN-binding domain
K7T73_10380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K7T73_10390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K7T73_10500	COG1690	Belongs to the RtcB family
K7T73_10515	COG1802	Transcriptional regulator
K7T73_10520	COG1231	oxidoreductase activity
K7T73_10530	COG1473	amidohydrolase
K7T73_10535	COG1288	antiporter activity
K7T73_10555	COG1136	(ABC) transporter
K7T73_10565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7T73_10575	COG0583	DNA-binding transcription factor activity
K7T73_10580	COG0693	protein deglycase activity
K7T73_10635	COG2318	DinB family
K7T73_10640	COG0346	lactoylglutathione lyase activity
K7T73_10645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K7T73_10660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_10665	COG3739	integral membrane protein
K7T73_10670	COG3655	Transcriptional regulator
K7T73_10690	COG1113	amino acid transport
K7T73_10700	COG0697	spore germination
K7T73_10705	COG1522	sequence-specific DNA binding
K7T73_10745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_10750	COG1309	transcriptional regulator
K7T73_10800	COG1522	sequence-specific DNA binding
K7T73_10835	COG0785	Cytochrome C biogenesis protein
K7T73_10840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K7T73_10860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K7T73_10870	COG2356	endonuclease I
K7T73_10875	COG0737	Belongs to the 5'-nucleotidase family
K7T73_10880	COG0840	transmembrane signaling receptor activity
K7T73_10920	COG1970	mechanosensitive ion channel activity
K7T73_10940	COG2258	MOSC domain
K7T73_10960	COG0488	(ABC) transporter
K7T73_10980	COG0577	efflux transmembrane transporter activity
K7T73_10985	COG1136	(ABC) transporter
K7T73_10990	COG0745	RESPONSE REGULATOR receiver
K7T73_10995	COG5002	protein histidine kinase activity
K7T73_11000	COG0456	acetyltransferase
K7T73_11060	COG0697	spore germination
K7T73_11105	COG2323	membrane
K7T73_11110	COG4667	esterase of the alpha-beta hydrolase superfamily
K7T73_11120	COG0534	Mate efflux family protein
K7T73_11125	COG2234	aminopeptidase activity
K7T73_11130	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_11140	COG2340	Cysteine-rich secretory protein family
K7T73_11150	COG2203	Gaf domain
K7T73_11150	COG3706	GGDEF domain
K7T73_11150	COG4251	negative regulation of phosphorylation
K7T73_11150	COG5001	Diguanylate cyclase
K7T73_11155	COG0793	Belongs to the peptidase S41A family
K7T73_11155	COG3409	Peptidoglycan-binding domain 1 protein
K7T73_11160	COG1876	peptidase activity
K7T73_11170	COG4326	sporulation control protein
K7T73_11180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7T73_11185	COG4698	Protein conserved in bacteria
K7T73_11190	COG2755	lipolytic protein G-D-S-L family
K7T73_11200	COG1307	EDD domain protein, DegV family
K7T73_11210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K7T73_11215	COG1757	Na H antiporter
K7T73_11225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K7T73_11230	COG4120	Belongs to the binding-protein-dependent transport system permease family
K7T73_11240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K7T73_11255	COG2136	Putative SAM-dependent methyltransferase
K7T73_11255	COG2521	methyltransferase
K7T73_11265	COG1413	lyase activity
K7T73_11270	COG0488	(ABC) transporter
K7T73_11280	COG2226	methyltransferase
K7T73_11290	COG1321	iron dependent repressor
K7T73_11295	COG1278	Cold shock
K7T73_11305	COG0328	RNA-DNA hybrid ribonuclease activity
K7T73_11310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K7T73_11315	COG0328	RNA-DNA hybrid ribonuclease activity
K7T73_11325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7T73_11330	COG2897	thiosulfate sulfurtransferase activity
K7T73_11340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K7T73_11350	COG2233	PERMEase
K7T73_11355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K7T73_11365	COG0116	Belongs to the methyltransferase superfamily
K7T73_11380	COG4474	Belongs to the UPF0398 family
K7T73_11385	COG3359	exonuclease
K7T73_11390	COG1111	helicase
K7T73_11390	COG1205	dead DEAH box helicase
K7T73_11410	COG3331	DNA recombination
K7T73_11415	COG4499	WXG100 protein secretion system (Wss), protein YukC
K7T73_11415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7T73_11425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K7T73_11430	COG3935	DnaD domain protein
K7T73_11435	COG0017	Asparaginyl-tRNA synthetase
K7T73_11440	COG0436	Aminotransferase
K7T73_11455	COG1199	ATP-dependent helicase activity
K7T73_11455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K7T73_11465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K7T73_11470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K7T73_11475	COG2133	pyrroloquinoline quinone binding
K7T73_11480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K7T73_11480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K7T73_11485	COG0617	tRNA 3'-terminal CCA addition
K7T73_11490	COG0438	transferase activity, transferring glycosyl groups
K7T73_11495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7T73_11500	COG1803	Methylglyoxal synthase
K7T73_11505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K7T73_11510	COG1694	Mazg nucleotide pyrophosphohydrolase
K7T73_11515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_11520	COG2738	Putative neutral zinc metallopeptidase
K7T73_11530	COG4347	Protein of unknown function (DUF1405)
K7T73_11540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K7T73_11555	COG5582	Belongs to the UPF0302 family
K7T73_11560	COG0457	Tetratricopeptide repeat
K7T73_11565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K7T73_11570	COG0287	Prephenate dehydrogenase
K7T73_11575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K7T73_11580	COG4401	Chorismate mutase type I
K7T73_11585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K7T73_11590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K7T73_11595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K7T73_11600	COG0105	UTP biosynthetic process
K7T73_11610	COG2226	methyltransferase
K7T73_11615	COG0142	geranyltranstransferase activity
K7T73_11625	COG0302	gtp cyclohydrolase
K7T73_11635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K7T73_11655	COG1160	GTP binding
K7T73_11665	COG0539	negative regulation of cytoplasmic translation
K7T73_11675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K7T73_11680	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
K7T73_11685	COG2959	enzyme of heme biosynthesis
K7T73_11690	COG3409	Peptidoglycan-binding domain 1 protein
K7T73_11690	COG3773	Cell wall hydrolase
K7T73_11695	COG2339	peptidase activity
K7T73_11700	COG0252	asparaginase activity
K7T73_11705	COG0492	ferredoxin-NADP+ reductase activity
K7T73_11715	COG1408	metallophosphoesterase
K7T73_11730	COG3546	catalase activity
K7T73_11735	COG1113	amino acid transport
K7T73_11740	COG1388	LysM domain
K7T73_11745	COG1266	CAAX protease self-immunity
K7T73_11750	COG0514	ATP-dependent DNA helicase (RecQ)
K7T73_11755	COG4955	Helix-turn-helix domain
K7T73_11760	COG1141	Ferredoxin
K7T73_11765	COG0840	transmembrane signaling receptor activity
K7T73_11770	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K7T73_11780	COG5002	protein histidine kinase activity
K7T73_11785	COG0745	RESPONSE REGULATOR receiver
K7T73_11790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K7T73_11795	COG1333	cytochrome c biogenesis protein
K7T73_11800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_11805	COG1187	pseudouridine synthase activity
K7T73_11810	COG0700	Nucleoside recognition
K7T73_11815	COG2715	membrane protein required for spore maturation
K7T73_11820	COG1686	Belongs to the peptidase S11 family
K7T73_11825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K7T73_11830	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K7T73_11835	COG1547	Domain of unknown function (DUF309)
K7T73_11850	COG0697	spore germination
K7T73_11870	COG2172	sigma factor antagonist activity
K7T73_11880	COG1686	Belongs to the peptidase S11 family
K7T73_11900	COG4974	Belongs to the 'phage' integrase family
K7T73_11910	COG0735	belongs to the Fur family
K7T73_11915	COG1300	Membrane
K7T73_11925	COG0667	Aldo Keto reductase
K7T73_11935	COG1073	alpha beta
K7T73_11955	COG0300	oxidoreductase activity
K7T73_11960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_11965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K7T73_11970	COG1902	pentaerythritol trinitrate reductase activity
K7T73_11975	COG1234	tRNA 3'-trailer cleavage
K7T73_11985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K7T73_11990	COG0531	amino acid
K7T73_12005	COG2195	Cleaves the N-terminal amino acid of tripeptides
K7T73_12010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K7T73_12015	COG0346	lactoylglutathione lyase activity
K7T73_12025	COG4129	membrane
K7T73_12035	COG1703	isobutyryl-CoA mutase activity
K7T73_12040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_12040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_12045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_12045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_12050	COG4086	secreted protein
K7T73_12055	COG2207	Transcriptional regulator
K7T73_12065	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7T73_12070	COG0022	dehydrogenase e1 component
K7T73_12075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K7T73_12080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K7T73_12095	COG3829	transcription factor binding
K7T73_12095	COG3290	protein histidine kinase activity
K7T73_12105	COG0584	glycerophosphoryl diester phosphodiesterase
K7T73_12110	COG0745	RESPONSE REGULATOR receiver
K7T73_12115	COG0750	zinc metalloprotease
K7T73_12120	COG1285	pathogenesis
K7T73_12125	COG0497	DNA recombination
K7T73_12130	COG1438	arginine binding
K7T73_12135	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K7T73_12140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K7T73_12150	COG1722	exodeoxyribonuclease VII activity
K7T73_12160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K7T73_12165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K7T73_12170	COG1302	Protein conserved in bacteria
K7T73_12175	COG0439	Biotin carboxylase
K7T73_12180	COG0511	ligase activity, forming carbon-carbon bonds
K7T73_12220	COG3854	ATPases associated with a variety of cellular activities
K7T73_12225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K7T73_12230	COG0006	proline dipeptidase activity
K7T73_12235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K7T73_12245	COG3872	metal-dependent enzyme
K7T73_12255	COG1752	Esterase of the alpha-beta hydrolase superfamily
K7T73_12260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7T73_12265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K7T73_12275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K7T73_12280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7T73_12285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K7T73_12290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K7T73_12295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K7T73_12330	COG4537	Required for transformation and DNA binding
K7T73_12335	COG1459	type II secretion system
K7T73_12510	COG2369	cell adhesion
K7T73_12525	COG1783	phage Terminase large subunit
K7T73_12620	COG0629	single-stranded DNA binding
K7T73_12625	COG0863	Belongs to the N(4) N(6)-methyltransferase family
K7T73_12640	COG1191	sigma factor activity
K7T73_12675	COG1191	sigma factor activity
K7T73_12685	COG1484	DNA-dependent DNA replication
K7T73_12815	COG1396	sequence-specific DNA binding
K7T73_12820	COG0582	viral genome integration into host DNA
K7T73_12825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K7T73_12925	COG3953	SLT domain
K7T73_12925	COG5412	phage tail tape measure protein
K7T73_12980	COG0740	serine-type endopeptidase activity
K7T73_13175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K7T73_13185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_13195	COG1368	sulfuric ester hydrolase activity
K7T73_13205	COG0457	Tetratricopeptide repeat
K7T73_13205	COG0705	Rhomboid family
K7T73_13210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K7T73_13230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K7T73_13235	COG0581	inorganic phosphate transmembrane transporter activity
K7T73_13240	COG0573	inorganic phosphate transmembrane transporter activity
K7T73_13245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K7T73_13250	COG0768	penicillin binding
K7T73_13260	COG0477	Major facilitator Superfamily
K7T73_13265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K7T73_13270	COG1283	sodium-dependent phosphate transmembrane transporter activity
K7T73_13275	COG5521	maltodextrose utilization protein MalA
K7T73_13290	COG4709	membrane
K7T73_13295	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
K7T73_13300	COG0735	belongs to the Fur family
K7T73_13305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K7T73_13310	COG1121	(ABC) transporter
K7T73_13315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_13325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K7T73_13340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K7T73_13345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K7T73_13350	COG2384	SAM-dependent methyltransferase
K7T73_13355	COG2010	Cytochrome c
K7T73_13365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K7T73_13370	COG0358	DNA primase activity
K7T73_13380	COG0517	IMP dehydrogenase activity
K7T73_13385	COG0751	glycine-tRNA ligase activity
K7T73_13395	COG1381	Involved in DNA repair and RecF pathway recombination
K7T73_13405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K7T73_13410	COG0295	cytidine deaminase activity
K7T73_13415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K7T73_13420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K7T73_13425	COG1702	phosphate starvation-inducible protein PhoH
K7T73_13445	COG4864	UPF0365 protein
K7T73_13450	COG1030	water channel activity
K7T73_13465	COG1610	YqeY-like protein
K7T73_13475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K7T73_13480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K7T73_13485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K7T73_13490	COG2264	protein methyltransferase activity
K7T73_13500	COG0443	Heat shock 70 kDa protein
K7T73_13505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K7T73_13510	COG1420	regulation of RNA biosynthetic process
K7T73_13515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K7T73_13520	COG0481	GTPase activity
K7T73_13530	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_13545	COG1466	dna polymerase III delta subunit
K7T73_13555	COG2333	competence protein COMEC
K7T73_13555	COG0658	competence protein
K7T73_13565	COG1596	polysaccharide export
K7T73_13565	COG1555	photosystem II stabilization
K7T73_13570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K7T73_13575	COG2226	methyltransferase
K7T73_13580	COG0799	negative regulation of ribosome biogenesis
K7T73_13585	COG1713	HD superfamily hydrolase involved in NAD metabolism
K7T73_13590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K7T73_13595	COG1534	Rna-binding protein
K7T73_13605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K7T73_13610	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K7T73_13620	COG0688	phosphatidylethanolamine metabolic process
K7T73_13625	COG1183	phosphatidylcholine synthase activity
K7T73_13640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K7T73_13655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K7T73_13660	COG0572	uridine kinase
K7T73_13665	COG0826	peptidase U32
K7T73_13670	COG0826	peptidase U32
K7T73_13675	COG4122	O-methyltransferase activity
K7T73_13680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K7T73_13685	COG3906	Belongs to the UPF0473 family
K7T73_13695	COG4472	Bacterial protein of unknown function (DUF965)
K7T73_13705	COG0628	permease
K7T73_13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K7T73_13730	COG1104	cysteine desulfurase activity
K7T73_13735	COG1959	2 iron, 2 sulfur cluster binding
K7T73_13740	COG2364	Membrane
K7T73_13745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K7T73_13755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K7T73_13760	COG1131	(ABC) transporter
K7T73_13765	COG1131	(ABC) transporter
K7T73_13770	COG1725	Transcriptional regulator
K7T73_13780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K7T73_13790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K7T73_13795	COG0124	histidyl-tRNA synthetase
K7T73_13800	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_13800	COG3103	Sh3 type 3 domain protein
K7T73_13800	COG4991	sh3 domain protein
K7T73_13805	COG1490	D-aminoacyl-tRNA deacylase activity
K7T73_13810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K7T73_13815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K7T73_13820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K7T73_13820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K7T73_13825	COG5416	Lipopolysaccharide assembly protein A domain
K7T73_13830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K7T73_13835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K7T73_13835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K7T73_13845	COG2244	polysaccharide biosynthetic process
K7T73_13850	COG2323	membrane
K7T73_13860	COG1862	Preprotein translocase
K7T73_13865	COG0343	queuine tRNA-ribosyltransferase activity
K7T73_13870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K7T73_13880	COG2255	four-way junction helicase activity
K7T73_13905	COG0523	cobalamin synthesis protein
K7T73_13910	COG1388	LysM domain
K7T73_13910	COG3858	chitin binding
K7T73_13935	COG0157	Belongs to the NadC ModD family
K7T73_13940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K7T73_13945	COG1104	cysteine desulfurase activity
K7T73_13950	COG1827	regulation of RNA biosynthetic process
K7T73_13955	COG0077	Prephenate dehydratase
K7T73_13960	COG4492	Belongs to the UPF0735 family
K7T73_13965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K7T73_13970	COG3290	protein histidine kinase activity
K7T73_13975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K7T73_13980	COG2868	ribosomal protein
K7T73_13985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K7T73_13995	COG1994	Peptidase M50
K7T73_14005	COG2894	cell division
K7T73_14015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K7T73_14020	COG1792	Involved in formation and maintenance of cell shape
K7T73_14025	COG1077	Cell shape determining protein MreB Mrl
K7T73_14030	COG2003	Belongs to the UPF0758 family
K7T73_14060	COG0424	maF-like protein
K7T73_14070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K7T73_14075	COG0285	dihydrofolate synthase activity
K7T73_14080	COG0525	valine-tRNA ligase activity
K7T73_14095	COG0531	amino acid
K7T73_14100	COG0833	amino acid
K7T73_14110	COG1388	LysM domain
K7T73_14110	COG1388	LysM domain
K7T73_14115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K7T73_14120	COG0113	porphobilinogen synthase activity
K7T73_14135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K7T73_14155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K7T73_14160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K7T73_14165	COG0470	DNA polymerase III
K7T73_14165	COG1067	ATP-dependent peptidase activity
K7T73_14175	COG0544	peptidyl-prolyl cis-trans isomerase activity
K7T73_14195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K7T73_14200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K7T73_14205	COG5401	PFAM Sporulation and spore germination
K7T73_14215	COG1846	Transcriptional regulator
K7T73_14220	COG2197	response regulator
K7T73_14225	COG0824	Thioesterase
K7T73_14230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K7T73_14235	COG1053	succinate dehydrogenase
K7T73_14240	COG2009	succinate dehydrogenase
K7T73_14245	COG1719	4-vinyl reductase, 4VR
K7T73_14250	COG0322	excinuclease ABC activity
K7T73_14255	COG3118	belongs to the thioredoxin family
K7T73_14260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K7T73_14265	COG2086	electron transfer activity
K7T73_14270	COG1024	Enoyl-CoA hydratase
K7T73_14275	COG1309	transcriptional regulator
K7T73_14280	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_14285	COG2720	vancomycin resistance protein
K7T73_14290	COG0071	Belongs to the small heat shock protein (HSP20) family
K7T73_14300	COG3766	membrane
K7T73_14305	COG1193	negative regulation of DNA recombination
K7T73_14310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K7T73_14310	COG1796	DNA polymerase
K7T73_14315	COG1286	toxin biosynthetic process
K7T73_14320	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K7T73_14330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K7T73_14330	COG0072	phenylalanine-tRNA ligase activity
K7T73_14335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K7T73_14340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K7T73_14400	COG0183	Belongs to the thiolase family
K7T73_14405	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_14410	COG1268	BioY protein
K7T73_14415	COG2814	Major facilitator Superfamily
K7T73_14420	COG5002	protein histidine kinase activity
K7T73_14425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K7T73_14430	COG5002	protein histidine kinase activity
K7T73_14430	COG2205	protein histidine kinase activity
K7T73_14430	COG0784	Response regulator, receiver
K7T73_14445	COG0531	amino acid
K7T73_14450	COG1714	RDD family
K7T73_14455	COG0501	Belongs to the peptidase M48B family
K7T73_14460	COG2271	Major facilitator Superfamily
K7T73_14465	COG0277	FAD linked oxidase domain protein
K7T73_14485	COG0628	permease
K7T73_14505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K7T73_14510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K7T73_14520	COG1363	Peptidase, m42
K7T73_14530	COG3326	Membrane
K7T73_14540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7T73_14545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K7T73_14550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K7T73_14555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7T73_14560	COG2508	Transcriptional regulator
K7T73_14570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K7T73_14575	COG0765	amino acid transport
K7T73_14580	COG0183	Belongs to the thiolase family
K7T73_14585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K7T73_14590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K7T73_14595	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K7T73_14600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K7T73_14605	COG1484	DNA-dependent DNA replication
K7T73_14610	COG3611	Membrane attachment protein
K7T73_14615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K7T73_14620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K7T73_14625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K7T73_14645	COG1971	Probably functions as a manganese efflux pump
K7T73_14650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K7T73_14655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7T73_14655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K7T73_14660	COG5002	protein histidine kinase activity
K7T73_14665	COG0745	RESPONSE REGULATOR receiver
K7T73_14670	COG0039	L-malate dehydrogenase activity
K7T73_14675	COG0538	isocitrate dehydrogenase activity
K7T73_14680	COG0372	Belongs to the citrate synthase family
K7T73_14685	COG2707	UPF0756 membrane protein
K7T73_14690	COG0628	permease
K7T73_14695	COG3030	protein affecting phage T7 exclusion by the F plasmid
K7T73_14705	COG0205	6-phosphofructokinase activity
K7T73_14710	COG0825	malonyl-CoA metabolic process
K7T73_14715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K7T73_14720	COG1725	Transcriptional regulator
K7T73_14725	COG0281	malic enzyme
K7T73_14730	COG0587	DNA-directed DNA polymerase activity
K7T73_14745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K7T73_14755	COG4109	DRTGG domain
K7T73_14760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K7T73_14765	COG0006	proline dipeptidase activity
K7T73_14770	COG0589	response to stress
K7T73_14775	COG0165	Argininosuccinate lyase
K7T73_14780	COG0137	argininosuccinate synthase activity
K7T73_14800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K7T73_14810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K7T73_14815	COG0827	DNA restriction-modification system
K7T73_14820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K7T73_14825	COG3874	Sporulation protein YtfJ
K7T73_14835	COG1714	RDD family
K7T73_14840	COG0616	signal peptide processing
K7T73_14845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K7T73_14850	COG2962	Rard protein
K7T73_14855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7T73_14860	COG0301	tRNA thio-modification
K7T73_14865	COG1104	cysteine desulfurase activity
K7T73_14870	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
K7T73_14875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K7T73_14880	COG1956	GAF domain-containing protein
K7T73_14885	COG2199	diguanylate cyclase activity
K7T73_14885	COG2203	Gaf domain
K7T73_14890	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K7T73_14900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K7T73_14905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K7T73_14910	COG0454	-acetyltransferase
K7T73_14915	COG0517	IMP dehydrogenase activity
K7T73_14920	COG0123	including yeast histone deacetylase and acetoin utilization protein
K7T73_14940	COG1605	Chorismate mutase
K7T73_14940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K7T73_14950	COG4980	gas vesicle protein
K7T73_14960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K7T73_14965	COG1674	ftsk spoiiie
K7T73_14965	COG1674	ftsk spoiiie
K7T73_14970	COG4848	Belongs to the UPF0354 family
K7T73_14975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_14985	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K7T73_14990	COG1363	Peptidase, m42
K7T73_15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_15010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K7T73_15015	COG0510	thiamine kinase activity
K7T73_15030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K7T73_15035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7T73_15040	COG1349	DNA-binding transcription factor activity
K7T73_15045	COG1187	pseudouridine synthase activity
K7T73_15050	COG0697	spore germination
K7T73_15055	COG2244	polysaccharide biosynthetic process
K7T73_15060	COG2081	HI0933 family
K7T73_15070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K7T73_15075	COG0495	leucyl-tRNA aminoacylation
K7T73_15080	COG2814	Major facilitator Superfamily
K7T73_15085	COG1242	4 iron, 4 sulfur cluster binding
K7T73_15100	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K7T73_15105	COG2267	carboxylic ester hydrolase activity
K7T73_15110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K7T73_15115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K7T73_15120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K7T73_15125	COG2409	Drug exporters of the RND superfamily
K7T73_15135	COG1506	peptidase
K7T73_15140	COG0494	nUDIX hydrolase
K7T73_15155	COG0783	Belongs to the Dps family
K7T73_15165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K7T73_15175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K7T73_15180	COG0596	Alpha beta hydrolase
K7T73_15185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K7T73_15190	COG1169	isochorismate synthase
K7T73_15195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K7T73_15315	COG0697	spore germination
K7T73_15470	COG5484	DNA packaging
K7T73_15470	COG3728	DNA packaging
K7T73_15480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
K7T73_15490	COG1266	CAAX protease self-immunity
K7T73_15495	COG0789	Transcriptional regulator
K7T73_15495	COG4978	Transcriptional regulator
K7T73_15550	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
K7T73_15570	COG3723	Recombinational DNA repair protein, rece pathway
K7T73_15575	COG5377	YqaJ viral recombinase family
K7T73_15605	COG1476	TRANSCRIPTIONal
K7T73_15610	COG3620	sequence-specific DNA binding
K7T73_15615	COG2856	Zn peptidase
K7T73_15655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K7T73_15665	COG1979	alcohol dehydrogenase
K7T73_15670	COG2155	Conserved Protein
K7T73_15675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K7T73_15680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K7T73_15690	COG3829	transcription factor binding
K7T73_15695	COG1757	Na H antiporter
K7T73_15700	COG1098	S1 RNA binding domain
K7T73_15705	COG0069	glutamate synthase activity
K7T73_15715	COG0436	Aminotransferase
K7T73_15720	COG1522	sequence-specific DNA binding
K7T73_15725	COG0833	amino acid
K7T73_15735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K7T73_15745	COG0720	synthase
K7T73_15750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K7T73_15760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K7T73_15770	COG5018	Exonuclease
K7T73_15775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7T73_15785	COG2111	Na H antiporter
K7T73_15785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K7T73_15790	COG2111	Na H antiporter
K7T73_15795	COG1006	Multisubunit Na H antiporter MnhC subunit
K7T73_15800	COG0651	ATP synthesis coupled electron transport
K7T73_15805	COG1863	multisubunit Na H antiporter MnhE subunit
K7T73_15810	COG2212	antiporter activity
K7T73_15815	COG1320	monovalent cation:proton antiporter activity
K7T73_15820	COG4876	unkown
K7T73_15825	COG2050	protein possibly involved in aromatic compounds catabolism
K7T73_15835	COG2056	Na+-H+ antiporter family
K7T73_15840	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_15845	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K7T73_15850	COG0028	Belongs to the TPP enzyme family
K7T73_15870	COG1252	NADH dehydrogenase
K7T73_15875	COG0702	epimerase
K7T73_15995	COG0316	Belongs to the HesB IscA family
K7T73_16005	COG4844	belongs to the
K7T73_16010	COG1252	NADH dehydrogenase
K7T73_16030	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_16040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K7T73_16045	COG4837	Protein of unknown function (DUF1462)
K7T73_16050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K7T73_16060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K7T73_16065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K7T73_16070	COG0647	UMP catabolic process
K7T73_16075	COG2445	Protein of unknown function DUF86
K7T73_16090	COG4470	Protein conserved in bacteria
K7T73_16100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K7T73_16105	COG0739	heme binding
K7T73_16115	COG0733	neurotransmitter:sodium symporter activity
K7T73_16125	COG0737	Belongs to the 5'-nucleotidase family
K7T73_16130	COG0730	response to heat
K7T73_16135	COG1801	Protein of unknown function DUF72
K7T73_16140	COG0719	Fe-S assembly protein
K7T73_16145	COG0822	iron-sulfur transferase activity
K7T73_16150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K7T73_16155	COG0719	Fe-S assembly protein
K7T73_16160	COG0396	ATPase activity
K7T73_16165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K7T73_16170	COG1464	Belongs to the NlpA lipoprotein family
K7T73_16175	COG2011	ABC-type metal ion transport system permease component
K7T73_16180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K7T73_16190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_16195	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K7T73_16200	COG0509	glycine decarboxylation via glycine cleavage system
K7T73_16205	COG1393	Belongs to the ArsC family
K7T73_16210	COG1960	acyl-CoA dehydrogenase activity
K7T73_16215	COG0183	Belongs to the thiolase family
K7T73_16220	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7T73_16220	COG1024	Enoyl-CoA hydratase
K7T73_16235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K7T73_16250	COG3263	regulation of cellular component size
K7T73_16255	COG3729	General stress protein
K7T73_16280	COG0179	Fumarylacetoacetate (FAA) hydrolase
K7T73_16285	COG0196	riboflavin kinase activity
K7T73_16305	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_16310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7T73_16315	COG0583	DNA-binding transcription factor activity
K7T73_16325	COG2076	Multidrug Resistance protein
K7T73_16330	COG2076	Multidrug Resistance protein
K7T73_16335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K7T73_16340	COG0473	3-isopropylmalate dehydrogenase activity
K7T73_16345	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_16350	COG4638	Rieske (2fe-2S)
K7T73_16355	COG1141	Ferredoxin
K7T73_16360	COG0492	ferredoxin-NADP+ reductase activity
K7T73_16365	COG3829	transcription factor binding
K7T73_16370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_16375	COG1846	Transcriptional regulator
K7T73_16380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K7T73_16390	COG0318	PFAM AMP-dependent synthetase and ligase
K7T73_16400	COG0833	amino acid
K7T73_16405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K7T73_16410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K7T73_16420	COG2814	Major facilitator Superfamily
K7T73_16435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K7T73_16450	COG0583	DNA-binding transcription factor activity
K7T73_16455	COG0010	Belongs to the arginase family
K7T73_16460	COG0786	glutamate:sodium symporter activity
K7T73_16475	COG0494	nUDIX hydrolase
K7T73_16485	COG0456	acetyltransferase
K7T73_16505	COG3850	Histidine kinase
K7T73_16505	COG5002	protein histidine kinase activity
K7T73_16560	COG0732	type I restriction modification DNA specificity domain
K7T73_16575	COG0432	Pfam Uncharacterised protein family UPF0047
K7T73_16610	COG3383	formate dehydrogenase (NAD+) activity
K7T73_16615	COG2116	formate transmembrane transporter activity
K7T73_16635	COG3858	chitin binding
K7T73_16635	COG1388	LysM domain
K7T73_16640	COG0590	tRNA wobble adenosine to inosine editing
K7T73_16650	COG1764	response to oxidative stress
K7T73_16685	COG1742	UPF0060 membrane protein
K7T73_16690	COG0589	response to stress
K7T73_16695	COG0772	Belongs to the SEDS family
K7T73_16705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_16715	COG0840	transmembrane signaling receptor activity
K7T73_16725	COG1733	regulation of RNA biosynthetic process
K7T73_16740	COG3852	Histidine kinase
K7T73_16745	COG2204	response regulator
K7T73_16750	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_16760	COG0363	glucosamine-6-phosphate deaminase activity
K7T73_16765	COG2169	Transcriptional regulator
K7T73_16770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K7T73_16775	COG1619	proteins homologs of microcin C7 resistance protein MccF
K7T73_16790	COG2340	Cysteine-rich secretory protein family
K7T73_16800	COG0745	RESPONSE REGULATOR receiver
K7T73_16805	COG5002	protein histidine kinase activity
K7T73_16820	COG3546	catalase activity
K7T73_16825	COG4607	ABC-type enterochelin transport system periplasmic component
K7T73_16830	COG4604	ABC transporter, ATP-binding protein
K7T73_16835	COG4605	iron ion homeostasis
K7T73_16840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_16850	COG2409	Drug exporters of the RND superfamily
K7T73_16860	COG5577	PFAM Coat F domain
K7T73_16865	COG5577	PFAM Coat F domain
K7T73_16885	COG1846	Transcriptional regulator
K7T73_16890	COG0586	Pfam SNARE associated Golgi protein
K7T73_16895	COG0736	holo-[acyl-carrier-protein] synthase activity
K7T73_16910	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_16920	COG3284	Transcriptional regulator
K7T73_16925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K7T73_16925	COG0392	lysyltransferase activity
K7T73_16930	COG1309	transcriptional regulator
K7T73_16940	COG1131	(ABC) transporter
K7T73_16945	COG0745	RESPONSE REGULATOR receiver
K7T73_16950	COG5002	protein histidine kinase activity
K7T73_16955	COG1999	signal sequence binding
K7T73_16965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K7T73_16975	COG1840	ABC-type Fe3 transport system, periplasmic component
K7T73_17005	COG1802	Transcriptional regulator
K7T73_17010	COG1114	Component of the transport system for branched-chain amino acids
K7T73_17015	COG0778	Nitroreductase
K7T73_17020	COG1733	regulation of RNA biosynthetic process
K7T73_17030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K7T73_17035	COG0557	exoribonuclease II activity
K7T73_17040	COG1647	Serine aminopeptidase, S33
K7T73_17045	COG0018	arginyl-trna synthetase
K7T73_17055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K7T73_17060	COG0148	phosphopyruvate hydratase activity
K7T73_17065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K7T73_17070	COG0149	triose-phosphate isomerase activity
K7T73_17075	COG0126	phosphoglycerate kinase activity
K7T73_17085	COG2390	Transcriptional regulator
K7T73_17095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K7T73_17105	COG0740	serine-type endopeptidase activity
K7T73_17110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K7T73_17115	COG1481	regulation of sporulation
K7T73_17120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K7T73_17125	COG1660	Displays ATPase and GTPase activities
K7T73_17130	COG1051	belongs to the nudix hydrolase family
K7T73_17135	COG0492	ferredoxin-NADP+ reductase activity
K7T73_17140	COG0457	Tetratricopeptide repeat
K7T73_17145	COG0140	phosphoribosyl-ATP diphosphatase activity
K7T73_17145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K7T73_17150	COG0107	imidazoleglycerol-phosphate synthase activity
K7T73_17155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K7T73_17160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K7T73_17165	COG0131	Imidazoleglycerol-phosphate dehydratase
K7T73_17170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K7T73_17175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K7T73_17180	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
K7T73_17185	COG0471	metal ion transport
K7T73_17190	COG4565	transcriptional regulatory protein
K7T73_17195	COG3290	protein histidine kinase activity
K7T73_17200	COG1966	Carbon starvation protein
K7T73_17205	COG0110	maltose O-acetyltransferase activity
K7T73_17210	COG0546	phosphoglycolate phosphatase activity
K7T73_17215	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K7T73_17225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
K7T73_17235	COG1950	PFAM Membrane protein of
K7T73_17240	COG3595	metallopeptidase activity
K7T73_17245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K7T73_17250	COG0556	nucleotide-excision repair
K7T73_17255	COG0730	response to heat
K7T73_17260	COG1054	Belongs to the UPF0176 family
K7T73_17265	COG1937	Protein conserved in bacteria
K7T73_17275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_17280	COG4897	Protein conserved in bacteria
K7T73_17290	COG1968	undecaprenyl-diphosphatase activity
K7T73_17300	COG0022	dehydrogenase e1 component
K7T73_17305	COG1253	flavin adenine dinucleotide binding
K7T73_17315	COG0745	RESPONSE REGULATOR receiver
K7T73_17320	COG2205	protein histidine kinase activity
K7T73_17325	COG1136	(ABC) transporter
K7T73_17330	COG0577	efflux transmembrane transporter activity
K7T73_17335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_17340	COG0529	Catalyzes the synthesis of activated sulfate
K7T73_17345	COG2046	Belongs to the sulfate adenylyltransferase family
K7T73_17350	COG0175	sulfate reduction
K7T73_17355	COG0406	alpha-ribazole phosphatase activity
K7T73_17360	COG1809	phosphosulfolactate synthase activity
K7T73_17365	COG2814	Major facilitator Superfamily
K7T73_17375	COG0730	response to heat
K7T73_17380	COG3647	Membrane
K7T73_17385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7T73_17390	COG3409	Peptidoglycan-binding domain 1 protein
K7T73_17390	COG0793	Belongs to the peptidase S41A family
K7T73_17395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K7T73_17410	COG0739	heme binding
K7T73_17415	COG2177	Part of the ABC transporter FtsEX involved in
K7T73_17420	COG2884	Cell division ATP-binding protein ftsE
K7T73_17435	COG0653	protein targeting
K7T73_17440	COG1405	negative regulation of cell septum assembly
K7T73_17440	COG3012	SEC-C Motif Domain Protein
K7T73_17460	COG1516	flagellar protein fliS
K7T73_17465	COG1334	flagellar protein FlaG
K7T73_17470	COG4895	conserved protein (DUF2196)
K7T73_17475	COG0386	Belongs to the glutathione peroxidase family
K7T73_17480	COG0737	Belongs to the 5'-nucleotidase family
K7T73_17490	COG0531	amino acid
K7T73_17495	COG0393	Putative heavy-metal-binding
K7T73_17515	COG2059	Chromate
K7T73_17520	COG2059	Chromate
K7T73_17525	COG0833	amino acid
K7T73_17530	COG1982	Orn Lys Arg decarboxylase major
K7T73_17535	COG3829	transcription factor binding
K7T73_17540	COG2304	oxidoreductase activity
K7T73_17595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K7T73_17600	COG2340	Cysteine-rich secretory protein family
K7T73_17615	COG0436	Aminotransferase
K7T73_17620	COG0028	Belongs to the TPP enzyme family
K7T73_17625	COG1301	dicarboxylic acid transport
K7T73_17630	COG1414	Transcriptional regulator
K7T73_17650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K7T73_17655	COG1653	transport
K7T73_17660	COG1175	transmembrane transport
K7T73_17665	COG0395	ABC-type sugar transport system, permease component
K7T73_17670	COG3842	ATPase activity
K7T73_17690	COG1516	flagellar protein fliS
K7T73_17695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K7T73_17700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K7T73_17710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
K7T73_17715	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
K7T73_17725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K7T73_17730	COG1256	bacterial-type flagellum assembly
K7T73_17730	COG4786	Flagellar basal body rod
K7T73_17750	COG1040	competence protein
K7T73_17755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K7T73_17760	COG3693	PFAM glycoside hydrolase, family 10
K7T73_17770	COG1307	EDD domain protein, DegV family
K7T73_17800	COG1522	sequence-specific DNA binding
K7T73_17805	COG0733	neurotransmitter:sodium symporter activity
K7T73_17820	COG3327	negative regulation of DNA-templated transcription, initiation
K7T73_17825	COG1024	Enoyl-CoA hydratase
K7T73_17830	COG0183	Belongs to the thiolase family
K7T73_17835	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7T73_17840	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_17845	COG1024	Enoyl-CoA hydratase
K7T73_17850	COG1024	Enoyl-CoA hydratase
K7T73_17875	COG3396	Phenylacetate-CoA oxygenase
K7T73_17890	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K7T73_17915	COG4585	Histidine kinase
K7T73_17925	COG1739	Uncharacterized protein family UPF0029
K7T73_17930	COG1316	TRANSCRIPTIONal
K7T73_17935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K7T73_17940	COG0653	protein targeting
K7T73_17955	COG1696	Membrane protein involved in D-alanine export
K7T73_17965	COG1388	LysM domain
K7T73_17965	COG0791	NLP P60 protein
K7T73_17970	COG0768	penicillin binding
K7T73_17975	COG0697	spore germination
K7T73_17980	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
K7T73_18000	COG3604	Transcriptional regulator
K7T73_18005	COG1929	Belongs to the glycerate kinase type-1 family
K7T73_18010	COG3284	Transcriptional regulator
K7T73_18015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K7T73_18020	COG0508	dehydrogenase complex catalyzes the overall conversion of
K7T73_18025	COG0022	dehydrogenase e1 component
K7T73_18030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K7T73_18045	COG1473	amidohydrolase
K7T73_18050	COG3584	3D domain protein
K7T73_18050	COG1388	LysM domain
K7T73_18055	COG1388	LysM domain
K7T73_18055	COG3584	3D domain protein
K7T73_18070	COG1404	Belongs to the peptidase S8 family
K7T73_18075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K7T73_18085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7T73_18105	COG2996	Protein conserved in bacteria
K7T73_18135	COG0527	aspartate kinase activity
K7T73_18140	COG0737	Belongs to the 5'-nucleotidase family
K7T73_18145	COG1361	Conserved repeat domain
K7T73_18150	COG1295	ribonuclease BN
K7T73_18160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K7T73_18165	COG2911	Protein conserved in bacteria
K7T73_18165	COG1361	Conserved repeat domain
K7T73_18165	COG3266	domain, Protein
K7T73_18175	COG0840	transmembrane signaling receptor activity
K7T73_18180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K7T73_18200	COG0726	polysaccharide deacetylase
K7T73_18220	COG0730	response to heat
K7T73_18225	COG1294	oxidase, subunit
K7T73_18230	COG1271	oxidase subunit
K7T73_18235	COG2197	response regulator
K7T73_18245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K7T73_18260	COG0039	L-malate dehydrogenase activity
K7T73_18265	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
K7T73_18270	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
K7T73_18285	COG1454	alcohol dehydrogenase
K7T73_18285	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_18295	COG4302	ethanolamine ammonia-lyase activity
K7T73_18300	COG4303	Ethanolamine ammonia lyase large subunit
K7T73_18310	COG4917	ethanolamine utilization protein
K7T73_18315	COG4810	utilization protein
K7T73_18320	COG3192	ethanolamine utilization protein
K7T73_18355	COG2814	Major facilitator Superfamily
K7T73_18360	COG1846	Transcriptional regulator
K7T73_18375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K7T73_18380	COG0833	amino acid
K7T73_18385	COG0577	efflux transmembrane transporter activity
K7T73_18385	COG1136	(ABC) transporter
K7T73_18390	COG1136	(ABC) transporter
K7T73_18405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K7T73_18410	COG0110	maltose O-acetyltransferase activity
K7T73_18415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K7T73_18465	COG4464	protein tyrosine phosphatase activity
K7T73_18470	COG0489	protein tyrosine kinase activity
K7T73_18475	COG3944	biosynthesis protein
K7T73_18485	COG0670	Belongs to the BI1 family
K7T73_18490	COG1316	TRANSCRIPTIONal
K7T73_18495	COG0840	transmembrane signaling receptor activity
K7T73_18525	COG1309	transcriptional regulator
K7T73_18530	COG3764	Sortase (surface protein transpeptidase)
K7T73_18535	COG3279	Response regulator of the LytR AlgR family
K7T73_18545	COG2972	Histidine kinase
K7T73_18545	COG0745	RESPONSE REGULATOR receiver
K7T73_18550	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_18555	COG0438	transferase activity, transferring glycosyl groups
K7T73_18560	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
K7T73_18585	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_18595	COG0728	peptidoglycan biosynthetic process
K7T73_18610	COG0791	NLP P60 protein
K7T73_18615	COG1404	Belongs to the peptidase S8 family
K7T73_18625	COG4715	Zinc finger, swim domain protein
K7T73_18630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K7T73_18640	COG0629	single-stranded DNA binding
K7T73_18675	COG4786	Flagellar basal body rod
K7T73_18680	COG4786	Flagellar basal body rod
K7T73_18685	COG1077	Cell shape determining protein MreB Mrl
K7T73_18690	COG1609	Transcriptional regulator
K7T73_18695	COG0739	heme binding
K7T73_18705	COG2385	sporulation resulting in formation of a cellular spore
K7T73_18710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K7T73_18720	COG4836	Membrane
K7T73_18725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K7T73_18730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K7T73_18735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K7T73_18745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K7T73_18750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K7T73_18755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K7T73_18760	COG0356	it plays a direct role in the translocation of protons across the membrane
K7T73_18775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K7T73_18780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K7T73_18785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K7T73_18795	COG0698	ribose 5-phosphate isomerase
K7T73_18800	COG0840	transmembrane signaling receptor activity
K7T73_18805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K7T73_18810	COG1971	Probably functions as a manganese efflux pump
K7T73_18815	COG0009	L-threonylcarbamoyladenylate synthase
K7T73_18825	COG2890	protein-(glutamine-N5) methyltransferase activity
K7T73_18830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K7T73_18835	COG1435	thymidine kinase activity
K7T73_18840	COG0254	rRNA binding
K7T73_18845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K7T73_18850	COG1494	fructose-1,6-bisphosphatase
K7T73_18855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K7T73_18860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K7T73_18865	COG0191	fructose-bisphosphate aldolase activity
K7T73_18870	COG2204	response regulator
K7T73_18880	COG0504	CTP synthase activity
K7T73_18885	COG3343	RNA polymerase activity
K7T73_18895	COG1703	isobutyryl-CoA mutase activity
K7T73_18895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_18895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K7T73_18905	COG1960	acyl-CoA dehydrogenase activity
K7T73_18910	COG1960	acyl-CoA dehydrogenase activity
K7T73_18915	COG1250	3-hydroxyacyl-CoA dehydrogenase
K7T73_18920	COG0183	Belongs to the thiolase family
K7T73_18925	COG0247	lactate metabolic process
K7T73_18925	COG2181	nitrate reductase activity
K7T73_18930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K7T73_18935	COG0018	arginyl-trna synthetase
K7T73_18950	COG0010	Belongs to the arginase family
K7T73_18955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K7T73_18960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K7T73_18970	COG1994	Peptidase M50
K7T73_18980	COG3465	dGTPase activity
K7T73_18985	COG1078	dGTPase activity
K7T73_19005	COG0280	phosphate acetyltransferase
K7T73_19020	COG2363	Small membrane protein
K7T73_19030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K7T73_19035	COG1288	antiporter activity
K7T73_19040	COG1737	Transcriptional regulator
K7T73_19045	COG1473	amidohydrolase
K7T73_19050	COG4948	Mandelate Racemase Muconate Lactonizing
K7T73_19055	COG0351	phosphomethylpyrimidine kinase
K7T73_19060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7T73_19065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K7T73_19070	COG1683	Conserved Protein
K7T73_19075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K7T73_19080	COG3314	Sporulation integral membrane protein YlbJ
K7T73_19085	COG0628	permease
K7T73_19100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K7T73_19105	COG3279	Response regulator of the LytR AlgR family
K7T73_19110	COG0427	acetyl-CoA hydrolase
K7T73_19120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K7T73_19125	COG0133	tryptophan synthase activity
K7T73_19135	COG0788	formyltetrahydrofolate deformylase activity
K7T73_19150	COG0733	neurotransmitter:sodium symporter activity
K7T73_19155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K7T73_19160	COG1301	dicarboxylic acid transport
K7T73_19170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K7T73_19205	COG2130	NADP-dependent
K7T73_19230	COG1879	ABC-type sugar transport system periplasmic component
K7T73_19235	COG1172	Belongs to the binding-protein-dependent transport system permease family
K7T73_19240	COG1129	ABC transporter
K7T73_19245	COG1869	D-ribose catabolic process
K7T73_19250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K7T73_19255	COG1609	Transcriptional regulator
K7T73_19260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K7T73_19265	COG3853	Toxic anion resistance protein (TelA)
K7T73_19280	COG1358	cellular component organization or biogenesis
K7T73_19295	COG0861	Integral membrane protein TerC family
K7T73_19300	COG2310	stress, protein
K7T73_19305	COG2310	stress, protein
K7T73_19310	COG2310	stress, protein
K7T73_19330	COG2195	Cleaves the N-terminal amino acid of tripeptides
K7T73_19335	COG0753	catalase activity
K7T73_19335	COG0693	protein deglycase activity
K7T73_19350	COG3829	transcription factor binding
K7T73_19350	COG3290	protein histidine kinase activity
K7T73_19355	COG2068	MobA-Related Protein
K7T73_19395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K7T73_19400	COG0439	Biotin carboxylase
K7T73_19410	COG1984	allophanate hydrolase subunit 2
K7T73_19425	COG0753	catalase activity
K7T73_19445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K7T73_19455	COG3689	TIGRFAM TIGR03943 family protein
K7T73_19460	COG0701	Predicted permease
K7T73_19465	COG3223	Belongs to the PsiE family
K7T73_19475	COG2321	neutral zinc metallopeptidase
K7T73_19480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_19490	COG0583	DNA-binding transcription factor activity
K7T73_19495	COG1380	Effector of murein hydrolase LrgA
K7T73_19500	COG1346	cytolysis
K7T73_19505	COG0492	ferredoxin-NADP+ reductase activity
K7T73_19510	COG1120	ATPase activity
K7T73_19515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K7T73_19520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_19525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_19530	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_19535	COG1271	oxidase subunit
K7T73_19540	COG1294	oxidase, subunit
K7T73_19545	COG0788	formyltetrahydrofolate deformylase activity
K7T73_19560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7T73_19560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K7T73_19570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K7T73_19575	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
K7T73_19585	COG0028	Belongs to the TPP enzyme family
K7T73_19600	COG0596	Alpha beta hydrolase
K7T73_19605	COG1966	Carbon starvation protein
K7T73_19615	COG3829	transcription factor binding
K7T73_19615	COG3290	protein histidine kinase activity
K7T73_19620	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_19625	COG2610	gluconate transmembrane transporter activity
K7T73_19630	COG1187	pseudouridine synthase activity
K7T73_19635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K7T73_19650	COG0583	DNA-binding transcription factor activity
K7T73_19665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_19670	COG5002	protein histidine kinase activity
K7T73_19675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K7T73_19685	COG0346	lactoylglutathione lyase activity
K7T73_19690	COG2205	protein histidine kinase activity
K7T73_19695	COG0745	RESPONSE REGULATOR receiver
K7T73_19705	COG0577	efflux transmembrane transporter activity
K7T73_19710	COG1136	(ABC) transporter
K7T73_19715	COG3541	Predicted nucleotidyltransferase
K7T73_19730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K7T73_19735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K7T73_19755	COG5002	protein histidine kinase activity
K7T73_19760	COG0745	RESPONSE REGULATOR receiver
K7T73_19790	COG0305	Participates in initiation and elongation during chromosome replication
K7T73_19795	COG0359	binds to the 23S rRNA
K7T73_19800	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K7T73_19810	COG0840	transmembrane signaling receptor activity
K7T73_19815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K7T73_19825	COG0360	Binds together with S18 to 16S ribosomal RNA
K7T73_19830	COG0012	GTP binding
K7T73_19840	COG4481	Protein conserved in bacteria
K7T73_19845	COG0668	transmembrane transport
K7T73_19860	COG1475	DNA binding
K7T73_19865	COG1192	Involved in chromosome partitioning
K7T73_19870	COG1475	DNA binding
K7T73_19875	COG0357	Ribosomal RNA small subunit methyltransferase G
K7T73_19880	COG0445	tRNA wobble uridine modification
K7T73_19890	COG1847	R3H domain protein
K7T73_19895	COG0706	membrane insertase activity
K7T73_19905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K7T73_19930	COG1368	sulfuric ester hydrolase activity
K7T73_19945	COG0697	spore germination
K7T73_19985	COG0531	amino acid
K7T73_19995	COG1114	Component of the transport system for branched-chain amino acids
K7T73_20015	COG1366	Belongs to the anti-sigma-factor antagonist family
K7T73_20015	COG2202	Pas domain
K7T73_20085	COG3177	Filamentation induced by cAMP protein fic
K7T73_20110	COG0741	lytic transglycosylase activity
K7T73_20110	COG0791	NLP P60 protein
K7T73_20245	COG1357	PFAM Pentapeptide repeats (8 copies)
K7T73_20365	COG2814	Major facilitator Superfamily
K7T73_20380	COG2031	fatty acid transporter
K7T73_20455	COG0745	RESPONSE REGULATOR receiver
K7T73_20460	COG2205	protein histidine kinase activity
K7T73_20465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K7T73_20470	COG1556	Lactate utilization protein
K7T73_20475	COG1139	Iron-sulfur cluster binding protein
K7T73_20480	COG0247	lactate metabolic process
K7T73_20485	COG1620	l-lactate permease
K7T73_20490	COG2186	Transcriptional regulator
K7T73_20495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K7T73_20500	COG1396	sequence-specific DNA binding
K7T73_20510	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
K7T73_20510	COG0662	Cupin 2, conserved barrel domain protein
K7T73_20520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K7T73_20550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K7T73_20560	COG0745	RESPONSE REGULATOR receiver
K7T73_20570	COG5002	protein histidine kinase activity
K7T73_20590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K7T73_20590	COG2755	lipolytic protein G-D-S-L family
K7T73_20600	COG1595	DNA-templated transcription, initiation
K7T73_20605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K7T73_20625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_20635	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_20665	COG3829	transcription factor binding
K7T73_20665	COG3290	protein histidine kinase activity
K7T73_20675	COG0506	proline dehydrogenase activity
K7T73_20680	COG1114	Component of the transport system for branched-chain amino acids
K7T73_20685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K7T73_20695	COG1061	Type III restriction enzyme res subunit
K7T73_20835	COG0346	lactoylglutathione lyase activity
K7T73_20845	COG1192	Involved in chromosome partitioning
K7T73_20850	COG0860	N-Acetylmuramoyl-L-alanine amidase
K7T73_20855	COG4336	lyase activity
K7T73_20860	COG1914	H( )-stimulated, divalent metal cation uptake system
K7T73_20865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K7T73_20870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K7T73_20875	COG1984	allophanate hydrolase subunit 2
K7T73_20880	COG1414	Transcriptional regulator
K7T73_20895	COG3693	PFAM glycoside hydrolase, family 10
K7T73_20915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K7T73_20935	COG2364	Membrane
K7T73_20940	COG1288	antiporter activity
K7T73_20945	COG3708	Transcriptional regulator
K7T73_20945	COG2207	Transcriptional regulator
K7T73_20965	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K7T73_20970	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K7T73_20980	COG2205	protein histidine kinase activity
K7T73_21035	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_21040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K7T73_21055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K7T73_21075	COG2329	Antibiotic biosynthesis monooxygenase
K7T73_21080	COG0789	Transcriptional regulator
K7T73_21100	COG1361	Conserved repeat domain
K7T73_21135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K7T73_21140	COG3938	Belongs to the proline racemase family
K7T73_21145	COG3938	Belongs to the proline racemase family
K7T73_21150	COG1757	Na H antiporter
K7T73_21155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K7T73_21160	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_21170	COG0601	transmembrane transport
K7T73_21175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K7T73_21180	COG4172	Belongs to the ABC transporter superfamily
K7T73_21190	COG0006	proline dipeptidase activity
K7T73_21195	COG4166	transmembrane transport
K7T73_21220	COG5609	conserved protein (DUF2294)
K7T73_21225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K7T73_21245	COG0196	riboflavin kinase activity
K7T73_21260	COG1113	amino acid transport
K7T73_21270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K7T73_21275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K7T73_21280	COG1012	belongs to the aldehyde dehydrogenase family
K7T73_21285	COG1757	Na H antiporter
K7T73_21295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K7T73_21300	COG1027	Aspartate ammonia-lyase
K7T73_21305	COG0069	glutamate synthase activity
K7T73_21315	COG0840	transmembrane signaling receptor activity
K7T73_21320	COG2197	response regulator
K7T73_21330	COG4326	sporulation control protein
K7T73_21345	COG4974	Belongs to the 'phage' integrase family
K7T73_21350	COG0371	Dehydrogenase
K7T73_21365	COG1473	amidohydrolase
K7T73_21370	COG1288	antiporter activity
K7T73_21375	COG0583	DNA-binding transcription factor activity
K7T73_21385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K7T73_21390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_21395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K7T73_21420	COG1475	DNA binding
K7T73_21430	COG0019	diaminopimelate decarboxylase activity
K7T73_21440	COG4264	IucA IucC family
K7T73_21445	COG2423	ornithine cyclodeaminase activity
K7T73_21455	COG2814	Major facilitator Superfamily
K7T73_21465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K7T73_21480	COG0697	spore germination
K7T73_21535	COG0583	DNA-binding transcription factor activity
K7T73_21550	COG1335	isochorismatase
K7T73_21560	COG3290	protein histidine kinase activity
K7T73_21560	COG3829	transcription factor binding
K7T73_21580	COG1028	Short-chain dehydrogenase reductase Sdr
K7T73_21585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K7T73_21590	COG5002	protein histidine kinase activity
K7T73_21590	COG2198	Histidine kinase
K7T73_21590	COG0784	Response regulator, receiver
K7T73_21600	COG3279	Response regulator of the LytR AlgR family
K7T73_21630	COG2814	Major facilitator Superfamily
K7T73_21690	COG2132	Multicopper oxidase
K7T73_21700	COG2207	Transcriptional regulator
K7T73_21700	COG3708	Transcriptional regulator
K7T73_21715	COG0400	carboxylic ester hydrolase activity
K7T73_21720	COG0346	lactoylglutathione lyase activity
K7T73_21730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K7T73_21780	COG0772	Belongs to the SEDS family
K7T73_21785	COG0582	viral genome integration into host DNA
K7T73_21800	COG1028	Short-chain dehydrogenase reductase Sdr