locus-tag	class	description
BBEV_0003	COG0592	DNA-directed DNA polymerase activity
BBEV_0004	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBEV_0006	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBEV_0007	COG0706	membrane insertase activity
BBEV_0008	COG1847	R3H domain protein
BBEV_0009	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBEV_0010	COG0445	tRNA wobble uridine modification
BBEV_0012	COG1475	DNA binding
BBEV_0013	COG1192	Involved in chromosome partitioning
BBEV_0015	COG1475	DNA binding
BBEV_0016	COG1104	cysteine desulfurase activity
BBEV_0017	COG1811	Na channel or pump
BBEV_0018	COG4481	Protein conserved in bacteria
BBEV_0019	COG0012	GTP binding
BBEV_0020	COG0360	Binds together with S18 to 16S ribosomal RNA
BBEV_0021	COG0629	single-stranded DNA binding
BBEV_0022	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBEV_0023	COG4241	membrane
BBEV_0024	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BBEV_0025	COG0359	binds to the 23S rRNA
BBEV_0026	COG0305	Participates in initiation and elongation during chromosome replication
BBEV_0027	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBEV_0035	COG0745	RESPONSE REGULATOR receiver
BBEV_0036	COG5002	protein histidine kinase activity
BBEV_0037	COG4863	YycH protein
BBEV_0038	COG4853	Protein conserved in bacteria
BBEV_0039	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBEV_0040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBEV_0043	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBEV_0045	COG1088	dTDP-glucose 4,6-dehydratase activity
BBEV_0047	COG1187	pseudouridine synthase activity
BBEV_0048	COG0579	oxidoreductase
BBEV_0049	COG3706	GGDEF domain
BBEV_0049	COG4251	negative regulation of phosphorylation
BBEV_0049	COG2203	Gaf domain
BBEV_0049	COG5001	Diguanylate cyclase
BBEV_0051	COG1131	(ABC) transporter
BBEV_0053	COG3239	Fatty acid desaturase
BBEV_0054	COG4585	Histidine kinase
BBEV_0055	COG2197	response regulator
BBEV_0056	COG3706	GGDEF domain
BBEV_0056	COG0745	RESPONSE REGULATOR receiver
BBEV_0058	COG0493	'glutamate synthase
BBEV_0060	COG2897	thiosulfate sulfurtransferase activity
BBEV_0061	COG0398	Pfam SNARE associated Golgi protein
BBEV_0062	COG4134	Bacterial extracellular solute-binding protein
BBEV_0065	COG3842	ATPase activity
BBEV_0067	COG4608	Belongs to the ABC transporter superfamily
BBEV_0068	COG0444	Belongs to the ABC transporter superfamily
BBEV_0071	COG0747	negative chemotaxis
BBEV_0072	COG0527	aspartate kinase activity
BBEV_0075	COG0561	phosphatase activity
BBEV_0076	COG0083	homoserine kinase activity
BBEV_0077	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBEV_0082	COG0706	membrane insertase activity
BBEV_0083	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBEV_0084	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBEV_0086	COG1794	racemase activity, acting on amino acids and derivatives
BBEV_0090	COG1072	(Pantothenic acid kinase))
BBEV_0091	COG0251	oxidation-reduction process
BBEV_0093	COG2309	aminopeptidase activity
BBEV_0094	COG1368	sulfuric ester hydrolase activity
BBEV_0098	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBEV_0099	COG0840	transmembrane signaling receptor activity
BBEV_0102	COG1621	beta-fructofuranosidase activity
BBEV_0103	COG2201	protein-glutamate methylesterase activity
BBEV_0104	COG2084	Dehydrogenase
BBEV_0105	COG5002	protein histidine kinase activity
BBEV_0106	COG0702	epimerase
BBEV_0109	COG0456	acetyltransferase
BBEV_0111	COG1024	Enoyl-CoA hydratase
BBEV_0112	COG1902	pentaerythritol trinitrate reductase activity
BBEV_0112	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_0113	COG0280	phosphate acetyltransferase
BBEV_0114	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBEV_0116	COG0095	Lipoate-protein ligase
BBEV_0117	COG4844	belongs to the
BBEV_0118	COG1078	dGTPase activity
BBEV_0123	COG0010	Belongs to the arginase family
BBEV_0126	COG0601	transmembrane transport
BBEV_0127	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_0128	COG0444	Belongs to the ABC transporter superfamily
BBEV_0129	COG4608	Belongs to the ABC transporter superfamily
BBEV_0130	COG3620	sequence-specific DNA binding
BBEV_0132	COG0018	arginyl-trna synthetase
BBEV_0133	COG0840	transmembrane signaling receptor activity
BBEV_0133	COG3290	protein histidine kinase activity
BBEV_0134	COG1349	DNA-binding transcription factor activity
BBEV_0135	COG3395	kinase activity
BBEV_0136	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBEV_0137	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_0139	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBEV_0141	COG1725	Transcriptional regulator
BBEV_0142	COG1131	(ABC) transporter
BBEV_0144	COG1132	(ABC) transporter
BBEV_0147	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBEV_0149	COG0247	lactate metabolic process
BBEV_0149	COG2181	nitrate reductase activity
BBEV_0150	COG0183	Belongs to the thiolase family
BBEV_0151	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBEV_0152	COG1960	acyl-CoA dehydrogenase activity
BBEV_0153	COG1960	acyl-CoA dehydrogenase activity
BBEV_0155	COG1703	isobutyryl-CoA mutase activity
BBEV_0155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_0155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_0156	COG3343	RNA polymerase activity
BBEV_0157	COG0504	CTP synthase activity
BBEV_0159	COG2204	response regulator
BBEV_0161	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBEV_0162	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBEV_0163	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBEV_0164	COG0254	rRNA binding
BBEV_0165	COG1435	thymidine kinase activity
BBEV_0166	COG0840	transmembrane signaling receptor activity
BBEV_0167	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_0168	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBEV_0169	COG2890	protein-(glutamine-N5) methyltransferase activity
BBEV_0170	COG0009	L-threonylcarbamoyladenylate synthase
BBEV_0173	COG0840	transmembrane signaling receptor activity
BBEV_0174	COG0698	ribose 5-phosphate isomerase
BBEV_0177	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBEV_0178	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBEV_0179	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBEV_0182	COG0356	it plays a direct role in the translocation of protons across the membrane
BBEV_0185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBEV_0186	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBEV_0188	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBEV_0189	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBEV_0191	COG1879	ABC-type sugar transport system periplasmic component
BBEV_0192	COG2972	Histidine kinase
BBEV_0193	COG2207	Transcriptional regulator
BBEV_0193	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBEV_0194	COG4213	ABC transporter substrate-binding protein
BBEV_0195	COG1129	ABC transporter
BBEV_0196	COG4214	carbohydrate transport
BBEV_0198	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBEV_0199	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBEV_0200	COG0649	NAD binding
BBEV_0201	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BBEV_0203	COG0839	Belongs to the complex I subunit 6 family
BBEV_0204	COG0713	ATP synthesis coupled electron transport
BBEV_0205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BBEV_0207	COG1007	ATP synthesis coupled electron transport
BBEV_0210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBEV_0211	COG1077	Cell shape determining protein MreB Mrl
BBEV_0212	COG4786	Flagellar basal body rod
BBEV_0222	COG2244	polysaccharide biosynthetic process
BBEV_0224	COG3883	PFAM NLP P60 protein
BBEV_0224	COG0791	NLP P60 protein
BBEV_0225	COG1316	TRANSCRIPTIONal
BBEV_0226	COG1388	LysM domain
BBEV_0226	COG0791	NLP P60 protein
BBEV_0228	COG2843	Capsule synthesis protein
BBEV_0232	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_0233	COG0778	Nitroreductase
BBEV_0239	COG1609	Transcriptional regulator
BBEV_0240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_0241	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BBEV_0246	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_0250	COG3944	biosynthesis protein
BBEV_0251	COG0489	protein tyrosine kinase activity
BBEV_0253	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBEV_0256	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBEV_0257	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBEV_0266	COG1216	Glycosyl transferase, family 2
BBEV_0266	COG1442	glycosyl transferase family 8
BBEV_0271	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBEV_0278	COG1484	DNA-dependent DNA replication
BBEV_0281	COG1316	TRANSCRIPTIONal
BBEV_0285	COG2340	Cysteine-rich secretory protein family
BBEV_0286	COG2385	sporulation resulting in formation of a cellular spore
BBEV_0286	COG2247	cell wall binding repeat
BBEV_0290	COG1404	Belongs to the peptidase S8 family
BBEV_0291	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BBEV_0295	COG0463	Glycosyl transferase, family 2
BBEV_0298	COG1134	teichoic acid transport
BBEV_0302	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBEV_0303	COG2385	sporulation resulting in formation of a cellular spore
BBEV_0304	COG1316	TRANSCRIPTIONal
BBEV_0305	COG2247	cell wall binding repeat
BBEV_0305	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBEV_0309	COG0405	Gamma-glutamyltransferase
BBEV_0318	COG0464	growth
BBEV_0319	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_0320	COG0737	Belongs to the 5'-nucleotidase family
BBEV_0324	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BBEV_0328	COG1476	TRANSCRIPTIONal
BBEV_0334	COG0243	molybdopterin cofactor binding
BBEV_0337	COG0243	molybdopterin cofactor binding
BBEV_0338	COG0437	4 iron, 4 sulfur cluster binding
BBEV_0348	COG0791	NLP P60 protein
BBEV_0348	COG3883	PFAM NLP P60 protein
BBEV_0349	COG1653	transport
BBEV_0353	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBEV_0354	COG0477	Major facilitator Superfamily
BBEV_0357	COG0445	tRNA wobble uridine modification
BBEV_0360	COG1175	transmembrane transport
BBEV_0361	COG0395	ABC-type sugar transport system, permease component
BBEV_0363	COG2207	Transcriptional regulator
BBEV_0365	COG1472	Belongs to the glycosyl hydrolase 3 family
BBEV_0370	COG0745	RESPONSE REGULATOR receiver
BBEV_0373	COG1388	LysM domain
BBEV_0373	COG0791	NLP P60 protein
BBEV_0377	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_0379	COG3037	sugar-specific permease SgaT UlaA
BBEV_0380	COG0561	phosphatase activity
BBEV_0381	COG2258	MOSC domain
BBEV_0385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_0387	COG2508	Transcriptional regulator
BBEV_0389	COG1609	Transcriptional regulator
BBEV_0390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_0391	COG1869	D-ribose catabolic process
BBEV_0392	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBEV_0393	COG1879	ABC-type sugar transport system periplasmic component
BBEV_0399	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_0408	COG3046	protein related to deoxyribodipyrimidine photolyase
BBEV_0409	COG1349	DNA-binding transcription factor activity
BBEV_0410	COG1105	Belongs to the carbohydrate kinase PfkB family
BBEV_0411	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_0411	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBEV_0411	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBEV_0413	COG3706	GGDEF domain
BBEV_0415	COG5002	protein histidine kinase activity
BBEV_0416	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBEV_0418	COG1131	(ABC) transporter
BBEV_0419	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBEV_0421	COG2376	Dihydroxyacetone kinase
BBEV_0422	COG1461	Dihydroxyacetone kinase
BBEV_0423	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BBEV_0425	COG2376	Dihydroxyacetone kinase
BBEV_0428	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_0430	COG3829	transcription factor binding
BBEV_0430	COG3290	protein histidine kinase activity
BBEV_0431	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBEV_0432	COG4608	Belongs to the ABC transporter superfamily
BBEV_0433	COG0444	Belongs to the ABC transporter superfamily
BBEV_0434	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_0436	COG0747	negative chemotaxis
BBEV_0438	COG0701	Predicted permease
BBEV_0441	COG0574	Belongs to the PEP-utilizing enzyme family
BBEV_0441	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBEV_0442	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBEV_0445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBEV_0446	COG0583	DNA-binding transcription factor activity
BBEV_0447	COG1802	Transcriptional regulator
BBEV_0457	COG1053	succinate dehydrogenase
BBEV_0458	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBEV_0459	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_0460	COG0386	Belongs to the glutathione peroxidase family
BBEV_0461	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_0462	COG1620	l-lactate permease
BBEV_0464	COG0745	RESPONSE REGULATOR receiver
BBEV_0465	COG5002	protein histidine kinase activity
BBEV_0468	COG0385	Bile acid
BBEV_0471	COG3458	cephalosporin-C deacetylase activity
BBEV_0472	COG2318	DinB family
BBEV_0474	COG1482	cell wall glycoprotein biosynthetic process
BBEV_0475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBEV_0476	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBEV_0477	COG1984	allophanate hydrolase subunit 2
BBEV_0485	COG0326	Molecular chaperone. Has ATPase activity
BBEV_0490	COG1363	Peptidase, m42
BBEV_0492	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBEV_0493	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBEV_0496	COG0717	Belongs to the dCTP deaminase family
BBEV_0498	COG1739	Uncharacterized protein family UPF0029
BBEV_0501	COG1307	EDD domain protein, DegV family
BBEV_0502	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBEV_0503	COG1040	competence protein
BBEV_0505	COG2747	anti-sigma28 factor FlgM
BBEV_0507	COG4786	Flagellar basal body rod
BBEV_0507	COG1256	bacterial-type flagellum assembly
BBEV_0508	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_0510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBEV_0511	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBEV_0513	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_0515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBEV_0516	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_0518	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BBEV_0524	COG1278	Cold shock
BBEV_0527	COG1979	alcohol dehydrogenase
BBEV_0529	COG1295	ribonuclease BN
BBEV_0530	COG2267	carboxylic ester hydrolase activity
BBEV_0532	COG0702	epimerase
BBEV_0533	COG3437	response regulator, receiver
BBEV_0536	COG2203	Gaf domain
BBEV_0536	COG2199	diguanylate cyclase activity
BBEV_0537	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBEV_0538	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBEV_0540	COG1334	flagellar protein FlaG
BBEV_0541	COG1516	flagellar protein fliS
BBEV_0546	COG1278	Cold shock
BBEV_0547	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBEV_0549	COG3711	transcriptional antiterminator
BBEV_0550	COG0653	protein targeting
BBEV_0551	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBEV_0552	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_0554	COG2884	Cell division ATP-binding protein ftsE
BBEV_0555	COG2177	Part of the ABC transporter FtsEX involved in
BBEV_0556	COG0791	NLP P60 protein
BBEV_0556	COG3883	PFAM NLP P60 protein
BBEV_0557	COG3409	Peptidoglycan-binding domain 1 protein
BBEV_0557	COG0793	Belongs to the peptidase S41A family
BBEV_0558	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBEV_0559	COG0556	nucleotide-excision repair
BBEV_0560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBEV_0561	COG3595	metallopeptidase activity
BBEV_0562	COG1983	PspC domain protein
BBEV_0563	COG1950	PFAM Membrane protein of
BBEV_0564	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBEV_0565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBEV_0566	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBEV_0567	COG0546	phosphoglycolate phosphatase activity
BBEV_0568	COG0110	maltose O-acetyltransferase activity
BBEV_0569	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBEV_0570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BBEV_0571	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBEV_0572	COG0131	Imidazoleglycerol-phosphate dehydratase
BBEV_0573	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBEV_0574	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBEV_0575	COG0107	imidazoleglycerol-phosphate synthase activity
BBEV_0576	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBEV_0576	COG0140	phosphoribosyl-ATP diphosphatase activity
BBEV_0577	COG1233	COG1233 Phytoene dehydrogenase and related
BBEV_0579	COG0492	ferredoxin-NADP+ reductase activity
BBEV_0580	COG1660	Displays ATPase and GTPase activities
BBEV_0581	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBEV_0582	COG1481	regulation of sporulation
BBEV_0583	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_0584	COG0740	serine-type endopeptidase activity
BBEV_0585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BBEV_0587	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBEV_0589	COG0149	triose-phosphate isomerase activity
BBEV_0590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBEV_0591	COG0148	phosphopyruvate hydratase activity
BBEV_0592	COG0673	inositol 2-dehydrogenase activity
BBEV_0593	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBEV_0595	COG1647	Serine aminopeptidase, S33
BBEV_0596	COG0557	exoribonuclease II activity
BBEV_0597	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBEV_0598	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBEV_0599	COG0129	dihydroxy-acid dehydratase activity
BBEV_0603	COG5002	protein histidine kinase activity
BBEV_0604	COG0745	RESPONSE REGULATOR receiver
BBEV_0606	COG0201	protein transport
BBEV_0607	COG1024	Enoyl-CoA hydratase
BBEV_0607	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBEV_0608	COG0183	Belongs to the thiolase family
BBEV_0609	COG1960	acyl-CoA dehydrogenase activity
BBEV_0611	COG0509	glycine decarboxylation via glycine cleavage system
BBEV_0613	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBEV_0614	COG2011	ABC-type metal ion transport system permease component
BBEV_0615	COG1464	Belongs to the NlpA lipoprotein family
BBEV_0619	COG0396	ATPase activity
BBEV_0620	COG0719	Fe-S assembly protein
BBEV_0621	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBEV_0622	COG0822	iron-sulfur transferase activity
BBEV_0623	COG0719	Fe-S assembly protein
BBEV_0624	COG1801	Protein of unknown function DUF72
BBEV_0625	COG0730	response to heat
BBEV_0626	COG0737	Belongs to the 5'-nucleotidase family
BBEV_0628	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBEV_0629	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBEV_0630	COG1757	Na H antiporter
BBEV_0632	COG4470	Protein conserved in bacteria
BBEV_0634	COG1494	fructose-1,6-bisphosphatase
BBEV_0635	COG2445	Protein of unknown function DUF86
BBEV_0637	COG0647	UMP catabolic process
BBEV_0638	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBEV_0639	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BBEV_0640	COG4837	Protein of unknown function (DUF1462)
BBEV_0641	COG1252	NADH dehydrogenase
BBEV_0642	COG4844	belongs to the
BBEV_0644	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_0645	COG0316	Belongs to the HesB IscA family
BBEV_0646	COG0492	ferredoxin-NADP+ reductase activity
BBEV_0647	COG1252	NADH dehydrogenase
BBEV_0650	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BBEV_0652	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_0653	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_0676	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBEV_0677	COG0644	oxidoreductase
BBEV_0679	COG1522	sequence-specific DNA binding
BBEV_0680	COG0436	Aminotransferase
BBEV_0681	COG1098	S1 RNA binding domain
BBEV_0682	COG0166	Belongs to the GPI family
BBEV_0683	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBEV_0686	COG0582	viral genome integration into host DNA
BBEV_0687	COG4372	Transposase
BBEV_0697	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_0700	COG3290	protein histidine kinase activity
BBEV_0700	COG0840	transmembrane signaling receptor activity
BBEV_0703	COG0733	neurotransmitter:sodium symporter activity
BBEV_0706	COG2210	Belongs to the sulfur carrier protein TusA family
BBEV_0707	COG1937	Protein conserved in bacteria
BBEV_0708	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_0710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_0715	COG0589	response to stress
BBEV_0716	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BBEV_0718	COG0437	4 iron, 4 sulfur cluster binding
BBEV_0721	COG0746	molybdenum cofactor guanylyltransferase activity
BBEV_0724	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBEV_0725	COG0494	nUDIX hydrolase
BBEV_0726	COG1506	peptidase
BBEV_0728	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BBEV_0729	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBEV_0730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BBEV_0731	COG2267	carboxylic ester hydrolase activity
BBEV_0733	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBEV_0734	COG1242	4 iron, 4 sulfur cluster binding
BBEV_0735	COG0495	leucyl-tRNA aminoacylation
BBEV_0737	COG2081	HI0933 family
BBEV_0738	COG2081	HI0933 family
BBEV_0740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBEV_0741	COG0432	Pfam Uncharacterised protein family UPF0047
BBEV_0742	COG0772	Belongs to the SEDS family
BBEV_0743	COG0772	Belongs to the SEDS family
BBEV_0744	COG1187	pseudouridine synthase activity
BBEV_0745	COG1349	DNA-binding transcription factor activity
BBEV_0751	COG0058	SHG alpha-glucan phosphorylase activity
BBEV_0752	COG0297	glycogen (starch) synthase activity
BBEV_0753	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBEV_0754	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBEV_0755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BBEV_0756	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_0757	COG0510	thiamine kinase activity
BBEV_0758	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBEV_0759	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_0764	COG4848	Belongs to the UPF0354 family
BBEV_0768	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBEV_0772	COG3118	belongs to the thioredoxin family
BBEV_0773	COG0849	cell division
BBEV_0774	COG1605	Chorismate mutase
BBEV_0774	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBEV_0778	COG0454	-acetyltransferase
BBEV_0779	COG0517	IMP dehydrogenase activity
BBEV_0780	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBEV_0783	COG0656	L-ascorbic acid biosynthetic process
BBEV_0785	COG1131	(ABC) transporter
BBEV_0789	COG0798	PFAM Bile acid sodium symporter
BBEV_0793	COG0628	permease
BBEV_0796	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_0800	COG0535	radical SAM domain protein
BBEV_0803	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_0804	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BBEV_0805	COG1140	nitrate reductase beta subunit
BBEV_0806	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BBEV_0807	COG2181	nitrate reductase activity
BBEV_0808	COG2223	nitrite transmembrane transporter activity
BBEV_0809	COG2223	nitrite transmembrane transporter activity
BBEV_0813	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_0815	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BBEV_0818	COG1138	Cytochrome C-type biogenesis protein
BBEV_0822	COG1131	(ABC) transporter
BBEV_0824	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_0826	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_0827	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BBEV_0828	COG0351	phosphomethylpyrimidine kinase
BBEV_0829	COG0352	thiamine-phosphate diphosphorylase activity
BBEV_0831	COG0708	Exodeoxyribonuclease III
BBEV_0832	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_0836	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBEV_0837	COG0732	type I restriction modification DNA specificity domain
BBEV_0838	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_0847	COG1309	transcriptional regulator
BBEV_0857	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBEV_0858	COG2199	diguanylate cyclase activity
BBEV_0858	COG2203	Gaf domain
BBEV_0859	COG1956	GAF domain-containing protein
BBEV_0860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBEV_0861	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BBEV_0863	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BBEV_0864	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBEV_0865	COG0616	signal peptide processing
BBEV_0866	COG1714	RDD family
BBEV_0867	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBEV_0869	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBEV_0872	COG0589	response to stress
BBEV_0873	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_0875	COG0006	proline dipeptidase activity
BBEV_0876	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBEV_0878	COG4109	DRTGG domain
BBEV_0880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBEV_0881	COG0587	DNA-directed DNA polymerase activity
BBEV_0882	COG0281	malic enzyme
BBEV_0883	COG2186	Transcriptional regulator
BBEV_0884	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBEV_0885	COG0825	malonyl-CoA metabolic process
BBEV_0886	COG0205	6-phosphofructokinase activity
BBEV_0888	COG3030	protein affecting phage T7 exclusion by the F plasmid
BBEV_0889	COG2707	UPF0756 membrane protein
BBEV_0890	COG0372	Belongs to the citrate synthase family
BBEV_0891	COG0538	isocitrate dehydrogenase activity
BBEV_0892	COG0039	L-malate dehydrogenase activity
BBEV_0894	COG0745	RESPONSE REGULATOR receiver
BBEV_0895	COG5002	protein histidine kinase activity
BBEV_0896	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_0896	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_0897	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBEV_0898	COG0237	dephospho-CoA kinase activity
BBEV_0899	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBEV_0901	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBEV_0902	COG3611	Membrane attachment protein
BBEV_0903	COG1484	DNA-dependent DNA replication
BBEV_0904	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_0905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBEV_0907	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBEV_0908	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBEV_0909	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBEV_0912	COG4585	Histidine kinase
BBEV_0913	COG2197	response regulator
BBEV_0914	COG1131	(ABC) transporter
BBEV_0919	COG1363	Peptidase, m42
BBEV_0922	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBEV_0923	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBEV_0924	COG0072	phenylalanine-tRNA ligase activity
BBEV_0924	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_0927	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BBEV_0929	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBEV_0929	COG1796	DNA polymerase
BBEV_0930	COG1193	negative regulation of DNA recombination
BBEV_0931	COG3766	membrane
BBEV_0933	COG0318	PFAM AMP-dependent synthetase and ligase
BBEV_0934	COG0318	PFAM AMP-dependent synthetase and ligase
BBEV_0935	COG1309	transcriptional regulator
BBEV_0936	COG1024	Enoyl-CoA hydratase
BBEV_0937	COG2086	electron transfer activity
BBEV_0938	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBEV_0939	COG3118	belongs to the thioredoxin family
BBEV_0940	COG0322	excinuclease ABC activity
BBEV_0942	COG1719	4-vinyl reductase, 4VR
BBEV_0943	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBEV_0944	COG2009	succinate dehydrogenase
BBEV_0945	COG1053	succinate dehydrogenase
BBEV_0946	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_0947	COG0824	Thioesterase
BBEV_0948	COG3711	transcriptional antiterminator
BBEV_0949	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_0950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBEV_0951	COG1846	Transcriptional regulator
BBEV_0954	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBEV_0955	COG0622	Phosphoesterase
BBEV_0958	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBEV_0959	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBEV_0961	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBEV_0962	COG1126	abc transporter atp-binding protein
BBEV_0963	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBEV_0964	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_0965	COG0181	hydroxymethylbilane synthase activity
BBEV_0967	COG0113	porphobilinogen synthase activity
BBEV_0968	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBEV_0974	COG2197	response regulator
BBEV_0975	COG0189	ligase activity
BBEV_0976	COG0189	ligase activity
BBEV_0977	COG0285	dihydrofolate synthase activity
BBEV_0981	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBEV_0986	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBEV_0991	COG1027	Aspartate ammonia-lyase
BBEV_0992	COG0424	maF-like protein
BBEV_0993	COG2003	Belongs to the UPF0758 family
BBEV_0994	COG1077	Cell shape determining protein MreB Mrl
BBEV_0995	COG1792	Involved in formation and maintenance of cell shape
BBEV_0996	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BBEV_0997	COG0850	regulation of cytokinetic process
BBEV_0998	COG2894	cell division
BBEV_0999	COG1653	transport
BBEV_1000	COG1609	Transcriptional regulator
BBEV_1003	COG1530	ribonuclease E activity
BBEV_1004	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBEV_1005	COG2868	ribosomal protein
BBEV_1007	COG1234	tRNA 3'-trailer cleavage
BBEV_1009	COG0573	inorganic phosphate transmembrane transporter activity
BBEV_1010	COG0581	inorganic phosphate transmembrane transporter activity
BBEV_1011	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBEV_1012	COG0704	Plays a role in the regulation of phosphate uptake
BBEV_1016	COG0840	transmembrane signaling receptor activity
BBEV_1016	COG3290	protein histidine kinase activity
BBEV_1018	COG0243	molybdopterin cofactor binding
BBEV_1019	COG0437	4 iron, 4 sulfur cluster binding
BBEV_1023	COG0686	Belongs to the AlaDH PNT family
BBEV_1026	COG5001	Diguanylate cyclase
BBEV_1026	COG3300	MHYT domain
BBEV_1027	COG0745	RESPONSE REGULATOR receiver
BBEV_1028	COG5002	protein histidine kinase activity
BBEV_1031	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBEV_1033	COG3153	acetyltransferase
BBEV_1033	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBEV_1034	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BBEV_1035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBEV_1037	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BBEV_1038	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBEV_1039	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBEV_1043	COG0066	3-isopropylmalate dehydratase activity
BBEV_1044	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBEV_1045	COG0473	3-isopropylmalate dehydrogenase activity
BBEV_1046	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBEV_1047	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBEV_1048	COG0440	acetolactate synthase activity
BBEV_1049	COG0028	Belongs to the TPP enzyme family
BBEV_1050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_1054	COG0667	Aldo Keto reductase
BBEV_1058	COG0024	Methionine aminopeptidase
BBEV_1060	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_1064	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBEV_1065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_1065	COG1522	sequence-specific DNA binding
BBEV_1066	COG2313	pseudouridylate synthase activity
BBEV_1068	COG1131	(ABC) transporter
BBEV_1069	COG1294	oxidase, subunit
BBEV_1070	COG1271	oxidase subunit
BBEV_1072	COG0702	epimerase
BBEV_1074	COG3842	ATPase activity
BBEV_1075	COG2508	Transcriptional regulator
BBEV_1077	COG4399	Belongs to the UPF0754 family
BBEV_1081	COG0420	3'-5' exonuclease activity
BBEV_1082	COG4717	serine-type aminopeptidase activity
BBEV_1083	COG0745	RESPONSE REGULATOR receiver
BBEV_1084	COG2205	protein histidine kinase activity
BBEV_1084	COG2770	Histidine kinase
BBEV_1085	COG3481	metal-dependent phosphohydrolase, HD sub domain
BBEV_1089	COG1846	Transcriptional regulator
BBEV_1091	COG0537	adenosine 5'-monophosphoramidase activity
BBEV_1092	COG1131	(ABC) transporter
BBEV_1095	COG1473	amidohydrolase
BBEV_1096	COG0785	Cytochrome C biogenesis protein
BBEV_1097	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_1098	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BBEV_1102	COG3290	protein histidine kinase activity
BBEV_1103	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBEV_1104	COG4492	Belongs to the UPF0735 family
BBEV_1105	COG0077	Prephenate dehydratase
BBEV_1106	COG0632	four-way junction helicase activity
BBEV_1109	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBEV_1110	COG0343	queuine tRNA-ribosyltransferase activity
BBEV_1111	COG1862	Preprotein translocase
BBEV_1114	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBEV_1114	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBEV_1115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBEV_1115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBEV_1116	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBEV_1116	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBEV_1117	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBEV_1119	COG1490	D-aminoacyl-tRNA deacylase activity
BBEV_1120	COG0124	histidyl-tRNA synthetase
BBEV_1121	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBEV_1122	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBEV_1123	COG1620	l-lactate permease
BBEV_1124	COG0247	lactate metabolic process
BBEV_1125	COG1139	Iron-sulfur cluster binding protein
BBEV_1126	COG1556	Lactate utilization protein
BBEV_1128	COG2364	Membrane
BBEV_1129	COG1959	2 iron, 2 sulfur cluster binding
BBEV_1130	COG1104	cysteine desulfurase activity
BBEV_1131	COG0482	sulfurtransferase activity
BBEV_1133	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBEV_1136	COG4472	Bacterial protein of unknown function (DUF965)
BBEV_1137	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBEV_1138	COG3906	Belongs to the UPF0473 family
BBEV_1143	COG0572	uridine kinase
BBEV_1144	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBEV_1146	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBEV_1149	COG4946	Tricorn protease homolog
BBEV_1149	COG1506	peptidase
BBEV_1149	COG0823	Involved in the tonB-independent uptake of proteins
BBEV_1151	COG0366	Alpha amylase catalytic
BBEV_1152	COG0803	Belongs to the bacterial solute-binding protein 9 family
BBEV_1153	COG1278	Cold shock
BBEV_1154	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBEV_1157	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_1157	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_1159	COG2333	competence protein COMEC
BBEV_1159	COG0658	competence protein
BBEV_1160	COG5522	Integral membrane protein (intg_mem_TP0381)
BBEV_1161	COG0494	nUDIX hydrolase
BBEV_1162	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBEV_1163	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBEV_1167	COG0484	heat shock protein binding
BBEV_1169	COG3300	MHYT domain
BBEV_1169	COG5001	Diguanylate cyclase
BBEV_1171	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBEV_1172	COG0656	L-ascorbic acid biosynthetic process
BBEV_1173	COG0095	Lipoate-protein ligase
BBEV_1174	COG0671	phosphoesterase, PA-phosphatase related
BBEV_1176	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_1177	COG0450	alkyl hydroperoxide reductase
BBEV_1179	COG0617	tRNA 3'-terminal CCA addition
BBEV_1180	COG1183	phosphatidylcholine synthase activity
BBEV_1181	COG0688	phosphatidylethanolamine metabolic process
BBEV_1182	COG3835	regulator
BBEV_1183	COG0277	FAD linked oxidase domain protein
BBEV_1184	COG0247	lactate metabolic process
BBEV_1193	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBEV_1194	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBEV_1196	COG1534	Rna-binding protein
BBEV_1197	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBEV_1198	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBEV_1199	COG0799	negative regulation of ribosome biogenesis
BBEV_1200	COG2226	methyltransferase
BBEV_1201	COG1555	photosystem II stabilization
BBEV_1201	COG1596	polysaccharide export
BBEV_1202	COG2333	competence protein COMEC
BBEV_1202	COG0658	competence protein
BBEV_1204	COG1466	dna polymerase III delta subunit
BBEV_1205	COG0268	Binds directly to 16S ribosomal RNA
BBEV_1206	COG0481	GTPase activity
BBEV_1207	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBEV_1208	COG1420	regulation of RNA biosynthetic process
BBEV_1211	COG0484	heat shock protein binding
BBEV_1212	COG2264	protein methyltransferase activity
BBEV_1213	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBEV_1214	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBEV_1215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBEV_1216	COG1610	YqeY-like protein
BBEV_1217	COG1030	water channel activity
BBEV_1218	COG4864	UPF0365 protein
BBEV_1220	COG1702	phosphate starvation-inducible protein PhoH
BBEV_1221	COG1480	7TM receptor with intracellular HD hydrolase
BBEV_1223	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBEV_1224	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBEV_1225	COG1381	Involved in DNA repair and RecF pathway recombination
BBEV_1226	COG0752	glycyl-tRNA synthetase alpha subunit
BBEV_1227	COG0751	glycine-tRNA ligase activity
BBEV_1228	COG0517	IMP dehydrogenase activity
BBEV_1229	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBEV_1231	COG0358	DNA primase activity
BBEV_1232	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBEV_1236	COG2384	SAM-dependent methyltransferase
BBEV_1237	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBEV_1238	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBEV_1239	COG1329	Transcriptional regulator
BBEV_1240	COG0513	Belongs to the DEAD box helicase family
BBEV_1241	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BBEV_1242	COG1121	(ABC) transporter
BBEV_1243	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_1245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBEV_1247	COG1121	(ABC) transporter
BBEV_1248	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_1249	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_1250	COG0735	belongs to the Fur family
BBEV_1251	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BBEV_1252	COG4086	secreted protein
BBEV_1254	COG5521	maltodextrose utilization protein MalA
BBEV_1259	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBEV_1263	COG3481	metal-dependent phosphohydrolase, HD sub domain
BBEV_1264	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBEV_1265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBEV_1267	COG0457	Tetratricopeptide repeat
BBEV_1267	COG0705	Rhomboid family
BBEV_1270	COG1940	carbohydrate kinase activity
BBEV_1271	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBEV_1272	COG0390	transport system, permease component
BBEV_1274	COG0011	TIGRFAM Protein of
BBEV_1277	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_1280	COG4980	gas vesicle protein
BBEV_1281	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBEV_1283	COG4537	Required for transformation and DNA binding
BBEV_1288	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBEV_1290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBEV_1291	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_1292	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_1294	COG1321	iron dependent repressor
BBEV_1297	COG0006	proline dipeptidase activity
BBEV_1298	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBEV_1301	COG0511	ligase activity, forming carbon-carbon bonds
BBEV_1302	COG0439	Biotin carboxylase
BBEV_1303	COG1302	Protein conserved in bacteria
BBEV_1304	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBEV_1306	COG1570	exodeoxyribonuclease VII activity
BBEV_1307	COG1722	exodeoxyribonuclease VII activity
BBEV_1310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBEV_1311	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBEV_1312	COG1438	arginine binding
BBEV_1313	COG0497	DNA recombination
BBEV_1316	COG3829	transcription factor binding
BBEV_1316	COG3290	protein histidine kinase activity
BBEV_1317	COG0280	phosphate acetyltransferase
BBEV_1320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBEV_1321	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBEV_1322	COG0022	dehydrogenase e1 component
BBEV_1323	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_1328	COG4129	membrane
BBEV_1330	COG0346	lactoylglutathione lyase activity
BBEV_1331	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBEV_1332	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBEV_1335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBEV_1337	COG2257	FlhB HrpN YscU SpaS Family
BBEV_1340	COG1728	Protein conserved in bacteria
BBEV_1341	COG0366	Alpha amylase catalytic
BBEV_1342	COG1609	Transcriptional regulator
BBEV_1345	COG1902	pentaerythritol trinitrate reductase activity
BBEV_1346	COG0517	IMP dehydrogenase activity
BBEV_1349	COG0789	Transcriptional regulator
BBEV_1352	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBEV_1353	COG0300	oxidoreductase activity
BBEV_1355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBEV_1357	COG2414	aldehyde ferredoxin oxidoreductase
BBEV_1362	COG1562	ergosterol biosynthetic process
BBEV_1368	COG0561	phosphatase activity
BBEV_1369	COG2190	(PTS) system
BBEV_1370	COG1968	undecaprenyl-diphosphatase activity
BBEV_1371	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_1372	COG0667	Aldo Keto reductase
BBEV_1373	COG0494	nUDIX hydrolase
BBEV_1374	COG0735	belongs to the Fur family
BBEV_1375	COG4974	Belongs to the 'phage' integrase family
BBEV_1376	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBEV_1379	COG0019	diaminopimelate decarboxylase activity
BBEV_1380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBEV_1385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBEV_1385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBEV_1386	COG0307	riboflavin synthase, alpha
BBEV_1387	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBEV_1387	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBEV_1388	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBEV_1389	COG1547	Domain of unknown function (DUF309)
BBEV_1390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBEV_1391	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBEV_1396	COG1187	pseudouridine synthase activity
BBEV_1397	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_1398	COG1333	cytochrome c biogenesis protein
BBEV_1399	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_1400	COG0745	RESPONSE REGULATOR receiver
BBEV_1401	COG5002	protein histidine kinase activity
BBEV_1402	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBEV_1403	COG2096	Adenosyltransferase
BBEV_1404	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBEV_1405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBEV_1406	COG2186	Transcriptional regulator
BBEV_1408	COG1141	Ferredoxin
BBEV_1409	COG4955	Helix-turn-helix domain
BBEV_1418	COG0789	Transcriptional regulator
BBEV_1419	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_1420	COG0492	ferredoxin-NADP+ reductase activity
BBEV_1422	COG2339	peptidase activity
BBEV_1426	COG0204	Acyl-transferase
BBEV_1430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBEV_1431	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBEV_1435	COG0302	gtp cyclohydrolase
BBEV_1437	COG0142	geranyltranstransferase activity
BBEV_1438	COG2226	methyltransferase
BBEV_1439	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BBEV_1440	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BBEV_1441	COG0142	geranyltranstransferase activity
BBEV_1442	COG0105	UTP biosynthetic process
BBEV_1443	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBEV_1444	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBEV_1445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBEV_1446	COG4401	Chorismate mutase type I
BBEV_1448	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBEV_1449	COG0134	indole-3-glycerol-phosphate synthase activity
BBEV_1450	COG0133	tryptophan synthase activity
BBEV_1451	COG0159	tryptophan synthase activity
BBEV_1452	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBEV_1453	COG0287	Prephenate dehydrogenase
BBEV_1454	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBEV_1456	COG5582	Belongs to the UPF0302 family
BBEV_1458	COG0723	plastoquinol--plastocyanin reductase activity
BBEV_1459	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBEV_1460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBEV_1460	COG2010	Cytochrome c
BBEV_1461	COG4347	Protein of unknown function (DUF1405)
BBEV_1462	COG2738	Putative neutral zinc metallopeptidase
BBEV_1463	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_1464	COG1694	Mazg nucleotide pyrophosphohydrolase
BBEV_1465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BBEV_1466	COG1803	Methylglyoxal synthase
BBEV_1468	COG0438	transferase activity, transferring glycosyl groups
BBEV_1469	COG0617	tRNA 3'-terminal CCA addition
BBEV_1471	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BBEV_1472	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBEV_1474	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBEV_1474	COG1199	ATP-dependent helicase activity
BBEV_1475	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_1477	COG0436	Aminotransferase
BBEV_1478	COG0017	Asparaginyl-tRNA synthetase
BBEV_1479	COG3935	DnaD domain protein
BBEV_1480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBEV_1481	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_1481	COG4499	WXG100 protein secretion system (Wss), protein YukC
BBEV_1482	COG3331	DNA recombination
BBEV_1486	COG1335	isochorismatase
BBEV_1488	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_1490	COG1413	lyase activity
BBEV_1492	COG3402	PFAM membrane-flanked domain
BBEV_1493	COG3428	Bacterial PH domain
BBEV_1497	COG2199	diguanylate cyclase activity
BBEV_1500	COG1597	lipid kinase activity
BBEV_1503	COG0805	protein transport
BBEV_1505	COG1428	Deoxynucleoside kinase
BBEV_1506	COG1428	Deoxynucleoside kinase
BBEV_1510	COG4667	esterase of the alpha-beta hydrolase superfamily
BBEV_1512	COG2814	Major facilitator Superfamily
BBEV_1515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBEV_1516	COG1554	hydrolase, family 65, central catalytic
BBEV_1517	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_1518	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBEV_1520	COG0114	fumarate hydratase activity
BBEV_1524	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_1525	COG1686	Belongs to the peptidase S11 family
BBEV_1527	COG0436	Aminotransferase
BBEV_1528	COG0567	Dehydrogenase, E1 component
BBEV_1529	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_1530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBEV_1533	COG2002	toxin-antitoxin pair type II binding
BBEV_1536	COG0583	DNA-binding transcription factor activity
BBEV_1537	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_1538	COG2205	protein histidine kinase activity
BBEV_1539	COG4372	Transposase
BBEV_1547	COG2508	Transcriptional regulator
BBEV_1548	COG0006	proline dipeptidase activity
BBEV_1549	COG0626	cystathionine gamma-synthase activity
BBEV_1551	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_1552	COG0444	Belongs to the ABC transporter superfamily
BBEV_1553	COG4608	Belongs to the ABC transporter superfamily
BBEV_1554	COG0747	negative chemotaxis
BBEV_1557	COG2814	Major facilitator Superfamily
BBEV_1559	COG0626	cystathionine gamma-synthase activity
BBEV_1560	COG2200	EAL domain
BBEV_1561	COG1067	ATP-dependent peptidase activity
BBEV_1562	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_1564	COG1597	lipid kinase activity
BBEV_1565	COG0133	tryptophan synthase activity
BBEV_1567	COG3706	GGDEF domain
BBEV_1567	COG0745	RESPONSE REGULATOR receiver
BBEV_1568	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBEV_1574	COG4152	abc transporter atp-binding protein
BBEV_1575	COG1668	transmembrane transport
BBEV_1576	COG0525	valine-tRNA ligase activity
BBEV_1578	COG2056	Na+-H+ antiporter family
BBEV_1581	COG1765	OsmC-like protein
BBEV_1583	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BBEV_1585	COG0247	lactate metabolic process
BBEV_1591	COG0697	spore germination
BBEV_1592	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBEV_1595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBEV_1596	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBEV_1599	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBEV_1600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBEV_1601	COG0398	Pfam SNARE associated Golgi protein
BBEV_1606	COG0488	(ABC) transporter
BBEV_1607	COG1454	alcohol dehydrogenase
BBEV_1607	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_1610	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_1610	COG1902	pentaerythritol trinitrate reductase activity
BBEV_1611	COG1764	response to oxidative stress
BBEV_1612	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_1614	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBEV_1615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBEV_1616	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBEV_1618	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBEV_1620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBEV_1621	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBEV_1622	COG0137	argininosuccinate synthase activity
BBEV_1623	COG0165	Argininosuccinate lyase
BBEV_1625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_1628	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_1631	COG0582	viral genome integration into host DNA
BBEV_1632	COG3180	Ammonia monooxygenase
BBEV_1633	COG1917	Cupin 2, conserved barrel domain protein
BBEV_1634	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBEV_1637	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBEV_1641	COG2848	UPF0210 protein
BBEV_1642	COG3830	Belongs to the UPF0237 family
BBEV_1644	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BBEV_1646	COG0004	ammonium transporteR
BBEV_1648	COG2176	DNA-directed DNA polymerase activity
BBEV_1649	COG0371	Dehydrogenase
BBEV_1651	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBEV_1652	COG2996	Protein conserved in bacteria
BBEV_1657	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BBEV_1658	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BBEV_1660	COG0561	phosphatase activity
BBEV_1662	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBEV_1663	COG0187	DNA topoisomerase II activity
BBEV_1664	COG1832	CoA-binding protein
BBEV_1665	COG0589	response to stress
BBEV_1666	COG1174	glycine betaine transport
BBEV_1667	COG1125	glycine betaine transport
BBEV_1667	COG0517	IMP dehydrogenase activity
BBEV_1668	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BBEV_1670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBEV_1671	COG0116	Belongs to the methyltransferase superfamily
BBEV_1672	COG0328	RNA-DNA hybrid ribonuclease activity
BBEV_1673	COG3599	regulation of cell shape
BBEV_1674	COG4474	Belongs to the UPF0398 family
BBEV_1675	COG2176	DNA-directed DNA polymerase activity
BBEV_1677	COG3359	exonuclease
BBEV_1678	COG1205	dead DEAH box helicase
BBEV_1678	COG1111	helicase
BBEV_1680	COG2814	Major facilitator Superfamily
BBEV_1683	COG1418	mRNA catabolic process
BBEV_1685	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_1686	COG0784	Response regulator, receiver
BBEV_1686	COG0835	chemotaxis
BBEV_1689	COG1131	(ABC) transporter
BBEV_1690	COG1725	Transcriptional regulator
BBEV_1691	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBEV_1692	COG1131	(ABC) transporter
BBEV_1701	COG2814	Major facilitator Superfamily
BBEV_1702	COG2200	EAL domain
BBEV_1703	COG0613	PHP domain protein
BBEV_1704	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BBEV_1707	COG0464	growth
BBEV_1709	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBEV_1715	COG0840	transmembrane signaling receptor activity
BBEV_1715	COG5278	phosphoserine phosphatase activity
BBEV_1716	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_1717	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_1719	COG0500	methyltransferase
BBEV_1719	COG3615	Tellurite resistance protein tehB
BBEV_1722	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBEV_1723	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBEV_1728	COG4846	Membrane protein involved in cytochrome C biogenesis
BBEV_1732	COG2217	Heavy metal translocating P-type atpase
BBEV_1733	COG1937	Protein conserved in bacteria
BBEV_1734	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BBEV_1735	COG3763	UPF0154 protein
BBEV_1736	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBEV_1737	COG4224	UPF0291 protein
BBEV_1738	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BBEV_1740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBEV_1742	COG0174	glutamine synthetase
BBEV_1743	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BBEV_1745	COG1923	regulation of RNA biosynthetic process
BBEV_1746	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBEV_1747	COG2136	Putative SAM-dependent methyltransferase
BBEV_1747	COG2521	methyltransferase
BBEV_1748	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBEV_1749	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBEV_1750	COG4550	Control of competence regulator ComK, YlbF/YmcA
BBEV_1751	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBEV_1752	COG0156	8-amino-7-oxononanoate synthase activity
BBEV_1753	COG1063	alcohol dehydrogenase
BBEV_1754	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBEV_1755	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_1755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBEV_1757	COG2359	stage V sporulation protein S
BBEV_1758	COG1692	metallophosphoesterase
BBEV_1759	COG1418	mRNA catabolic process
BBEV_1760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBEV_1761	COG0513	Belongs to the DEAD box helicase family
BBEV_1762	COG1546	Belongs to the CinA family
BBEV_1762	COG1058	Belongs to the CinA family
BBEV_1763	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBEV_1764	COG1426	Protein conserved in bacteria
BBEV_1766	COG0300	oxidoreductase activity
BBEV_1767	COG0612	Peptidase, M16
BBEV_1768	COG0612	Peptidase, M16
BBEV_1769	COG2188	Transcriptional regulator
BBEV_1770	COG4980	gas vesicle protein
BBEV_1770	COG1674	ftsk spoiiie
BBEV_1771	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBEV_1772	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBEV_1773	COG0527	aspartate kinase activity
BBEV_1774	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBEV_1775	COG0612	Peptidase, M16
BBEV_1776	COG1185	polyribonucleotide nucleotidyltransferase activity
BBEV_1777	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBEV_1778	COG0196	riboflavin kinase activity
BBEV_1780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBEV_1781	COG1550	Protein conserved in bacteria
BBEV_1782	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBEV_1784	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBEV_1785	COG0195	Participates in both transcription termination and antitermination
BBEV_1786	COG0779	Required for maturation of 30S ribosomal subunits
BBEV_1787	COG2176	DNA-directed DNA polymerase activity
BBEV_1788	COG0442	prolyl-tRNA aminoacylation
BBEV_1789	COG0750	zinc metalloprotease
BBEV_1791	COG4589	Belongs to the CDS family
BBEV_1792	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBEV_1793	COG0233	cytoplasmic translational termination
BBEV_1794	COG0528	UMP kinase activity
BBEV_1795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBEV_1796	COG0052	Belongs to the universal ribosomal protein uS2 family
BBEV_1800	COG1191	sigma factor activity
BBEV_1802	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BBEV_1803	COG1776	CheC inhibitor of MCP methylation
BBEV_1804	COG0835	chemotaxis
BBEV_1805	COG2198	Histidine kinase
BBEV_1805	COG0643	Histidine kinase
BBEV_1806	COG2201	protein-glutamate methylesterase activity
BBEV_1807	COG0455	bacterial-type flagellum organization
BBEV_1808	COG1419	protein localization to endoplasmic reticulum
BBEV_1809	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBEV_1810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBEV_1811	COG1684	flagellar biosynthetic protein fliR
BBEV_1812	COG1987	bacterial-type flagellum assembly
BBEV_1813	COG1338	Plays a role in the flagellum-specific transport system
BBEV_1814	COG3190	flagellar
BBEV_1815	COG2201	protein-glutamate methylesterase activity
BBEV_1816	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_1816	COG1776	CheC inhibitor of MCP methylation
BBEV_1817	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_1819	COG1582	Flagellar protein (FlbD)
BBEV_1822	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBEV_1826	COG1157	protein secretion by the type III secretion system
BBEV_1827	COG1317	bacterial-type flagellum organization
BBEV_1828	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_1829	COG1766	The M ring may be actively involved in energy transduction
BBEV_1830	COG1677	Flagellar hook-basal body complex protein FliE
BBEV_1831	COG1558	bacterial-type flagellum-dependent cell motility
BBEV_1832	COG1815	bacterial-type flagellum-dependent cell motility
BBEV_1833	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBEV_1834	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBEV_1835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBEV_1836	COG4974	Belongs to the 'phage' integrase family
BBEV_1837	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBEV_1838	COG0758	DNA mediated transformation
BBEV_1839	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBEV_1840	COG0045	succinate-CoA ligase (ADP-forming) activity
BBEV_1841	COG2257	FlhB HrpN YscU SpaS Family
BBEV_1843	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBEV_1846	COG0335	large ribosomal subunit rRNA binding
BBEV_1847	COG0336	Belongs to the RNA methyltransferase TrmD family
BBEV_1848	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBEV_1850	COG1837	Belongs to the UPF0109 family
BBEV_1851	COG0228	four-way junction DNA binding
BBEV_1852	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBEV_1853	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBEV_1854	COG0552	protein localization to endoplasmic reticulum
BBEV_1855	COG1196	nuclear chromosome segregation
BBEV_1856	COG4840	Belongs to the UPF0435 family
BBEV_1858	COG0571	ribonuclease III activity
BBEV_1859	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBEV_1860	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_1861	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBEV_1862	COG0416	fatty acid biosynthetic process
BBEV_1863	COG1349	DNA-binding transcription factor activity
BBEV_1864	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBEV_1865	COG1760	l-serine dehydratase
BBEV_1866	COG1760	l-serine dehydratase
BBEV_1867	COG1307	EDD domain protein, DegV family
BBEV_1868	COG1461	Dihydroxyacetone kinase
BBEV_1869	COG1302	Protein conserved in bacteria
BBEV_1870	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBEV_1871	COG1564	THIamine pyrophosphokinase
BBEV_1872	COG3859	Proton-coupled thiamine transporter YuaJ
BBEV_1873	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBEV_1874	COG1162	GTPase activity
BBEV_1875	COG0515	serine threonine protein kinase
BBEV_1875	COG2815	serine threonine protein kinase
BBEV_1876	COG0631	protein serine/threonine phosphatase activity
BBEV_1877	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBEV_1877	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBEV_1878	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBEV_1879	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBEV_1880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBEV_1881	COG1758	RNA polymerase activity
BBEV_1882	COG0194	GDP metabolic process
BBEV_1883	COG2052	Domain of unknown function (DUF370)
BBEV_1884	COG1561	YicC-like family, N-terminal region
BBEV_1886	COG1132	(ABC) transporter
BBEV_1887	COG1132	(ABC) transporter
BBEV_1890	COG0167	dihydroorotate dehydrogenase activity
BBEV_1892	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBEV_1893	COG0505	Belongs to the CarA family
BBEV_1894	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_1895	COG0540	Belongs to the ATCase OTCase family
BBEV_1897	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBEV_1898	COG0564	pseudouridine synthase activity
BBEV_1899	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBEV_1900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBEV_1901	COG3599	regulation of cell shape
BBEV_1902	COG2302	S4 RNA-binding domain
BBEV_1903	COG0762	integral membrane protein
BBEV_1904	COG1799	cell septum assembly
BBEV_1905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBEV_1906	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBEV_1907	COG0849	cell division
BBEV_1908	COG3856	small basic protein
BBEV_1909	COG3879	Bacterial protein of unknown function (DUF881)
BBEV_1910	COG3879	Bacterial protein of unknown function (DUF881)
BBEV_1911	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BBEV_1912	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBEV_1913	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBEV_1914	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBEV_1915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBEV_1916	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBEV_1917	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBEV_1920	COG0275	rRNA processing
BBEV_1921	COG2001	Belongs to the MraZ family
BBEV_1922	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BBEV_1924	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBEV_1925	COG0454	-acetyltransferase
BBEV_1926	COG1024	Enoyl-CoA hydratase
BBEV_1927	COG1399	metal-binding, possibly nucleic acid-binding protein
BBEV_1928	COG1323	Belongs to the UPF0348 family
BBEV_1929	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBEV_1930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBEV_1931	COG0742	ribosomal rna small subunit methyltransferase
BBEV_1932	COG4471	UPF0298 protein
BBEV_1933	COG3679	Belongs to the UPF0342 family
BBEV_1939	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBEV_1943	COG0783	Belongs to the Dps family
BBEV_1944	COG4838	Belongs to the UPF0358 family
BBEV_1945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BBEV_1947	COG4896	Protein conserved in bacteria
BBEV_1950	COG2801	Transposase and inactivated derivatives
BBEV_1951	COG0483	inositol monophosphate 1-phosphatase activity
BBEV_1953	COG4493	Belongs to the UPF0637 family
BBEV_1954	COG4476	Belongs to the UPF0223 family
BBEV_1955	COG1982	Orn Lys Arg decarboxylase major
BBEV_1961	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_1962	COG0022	dehydrogenase e1 component
BBEV_1966	COG0242	peptide deformylase activity
BBEV_1968	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBEV_1969	COG0569	domain protein
BBEV_1970	COG0668	transmembrane transport
BBEV_1971	COG1473	amidohydrolase
BBEV_1972	COG2171	N-acyltransferase activity
BBEV_1975	COG0668	transmembrane transport
BBEV_1976	COG0569	domain protein
BBEV_1978	COG0778	Nitroreductase
BBEV_1979	COG1854	S-ribosylhomocysteine lyase activity
BBEV_1982	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBEV_1984	COG2151	metal-sulfur cluster biosynthetic enzyme
BBEV_1986	COG0656	L-ascorbic acid biosynthetic process
BBEV_1987	COG0534	Mate efflux family protein
BBEV_1991	COG1595	DNA-templated transcription, initiation
BBEV_1992	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_1993	COG2224	Isocitrate lyase
BBEV_1994	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BBEV_1995	COG0493	'glutamate synthase
BBEV_1996	COG0069	glutamate synthase activity
BBEV_1996	COG0070	glutamate synthase
BBEV_1996	COG0067	glutamate synthase
BBEV_1999	COG5001	Diguanylate cyclase
BBEV_1999	COG3300	MHYT domain
BBEV_2004	COG0739	heme binding
BBEV_2009	COG0564	pseudouridine synthase activity
BBEV_2010	COG2357	RelA SpoT domain protein
BBEV_2012	COG0741	lytic transglycosylase activity
BBEV_2012	COG1196	nuclear chromosome segregation
BBEV_2012	COG0739	heme binding
BBEV_2013	COG2346	COG2346, Truncated hemoglobins
BBEV_2015	COG1164	Oligoendopeptidase f
BBEV_2018	COG1393	Belongs to the ArsC family
BBEV_2019	COG0456	acetyltransferase
BBEV_2021	COG1418	mRNA catabolic process
BBEV_2022	COG0530	calcium, potassium:sodium antiporter activity
BBEV_2023	COG0180	Tryptophanyl-tRNA synthetase
BBEV_2024	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_2025	COG1316	TRANSCRIPTIONal
BBEV_2026	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBEV_2027	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBEV_2029	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_2030	COG4841	protein insertion into membrane
BBEV_2031	COG0303	'Molybdopterin
BBEV_2032	COG1763	Mo-molybdopterin cofactor biosynthetic process
BBEV_2033	COG0314	molybdopterin synthase activity
BBEV_2035	COG1999	signal sequence binding
BBEV_2036	COG3336	cytochrome c oxidase
BBEV_2037	COG0561	phosphatase activity
BBEV_2040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BBEV_2043	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_2046	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2047	COG0628	permease
BBEV_2048	COG1609	Transcriptional regulator
BBEV_2049	COG3833	ABC-type maltose transport systems, permease component
BBEV_2050	COG1175	transmembrane transport
BBEV_2053	COG0662	Cupin 2, conserved barrel domain protein
BBEV_2053	COG2207	Transcriptional regulator
BBEV_2062	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2063	COG0628	permease
BBEV_2064	COG1609	Transcriptional regulator
BBEV_2066	COG3833	ABC-type maltose transport systems, permease component
BBEV_2067	COG1175	transmembrane transport
BBEV_2069	COG0662	Cupin 2, conserved barrel domain protein
BBEV_2069	COG2207	Transcriptional regulator
BBEV_2070	COG0534	Mate efflux family protein
BBEV_2074	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBEV_2075	COG1509	lysine 2,3-aminomutase activity
BBEV_2078	COG1032	radical SAM domain protein
BBEV_2079	COG2249	NAD(P)H dehydrogenase (quinone) activity
BBEV_2080	COG3300	MHYT domain
BBEV_2080	COG5001	Diguanylate cyclase
BBEV_2081	COG2154	pterin-4-alpha-carbinolamine dehydratase
BBEV_2083	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBEV_2084	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBEV_2085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_2086	COG1309	transcriptional regulator
BBEV_2093	COG3192	ethanolamine utilization protein
BBEV_2094	COG1489	DNA binding
BBEV_2098	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_2106	COG0217	transcriptional regulatory protein
BBEV_2111	COG1335	isochorismatase
BBEV_2112	COG1510	regulation of RNA biosynthetic process
BBEV_2118	COG5278	phosphoserine phosphatase activity
BBEV_2118	COG0840	transmembrane signaling receptor activity
BBEV_2122	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBEV_2123	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_2124	COG1116	anion transmembrane transporter activity
BBEV_2127	COG0584	glycerophosphoryl diester phosphodiesterase
BBEV_2128	COG2357	RelA SpoT domain protein
BBEV_2133	COG3381	protein complex oligomerization
BBEV_2135	COG0243	molybdopterin cofactor binding
BBEV_2137	COG4585	Histidine kinase
BBEV_2139	COG2720	vancomycin resistance protein
BBEV_2140	COG1461	Dihydroxyacetone kinase
BBEV_2143	COG2116	formate transmembrane transporter activity
BBEV_2150	COG0583	DNA-binding transcription factor activity
BBEV_2156	COG0154	amidase activity
BBEV_2157	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2163	COG0326	Molecular chaperone. Has ATPase activity
BBEV_2168	COG1104	cysteine desulfurase activity
BBEV_2170	COG0419	ATPase involved in DNA repair
BBEV_2179	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_2181	COG1360	Flagellar Motor Protein
BBEV_2189	COG3290	protein histidine kinase activity
BBEV_2189	COG3829	transcription factor binding
BBEV_2192	COG0840	transmembrane signaling receptor activity
BBEV_2193	COG0124	histidyl-tRNA synthetase
BBEV_2194	COG1349	DNA-binding transcription factor activity
BBEV_2195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBEV_2196	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BBEV_2197	COG0246	Mannitol dehydrogenase
BBEV_2199	COG2213	PTS system mannitol-specific
BBEV_2201	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBEV_2202	COG2048	Heterodisulfide reductase, subunit B
BBEV_2203	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_2204	COG1053	succinate dehydrogenase
BBEV_2206	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BBEV_2206	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BBEV_2207	COG0471	metal ion transport
BBEV_2208	COG4565	transcriptional regulatory protein
BBEV_2209	COG3290	protein histidine kinase activity
BBEV_2211	COG0437	4 iron, 4 sulfur cluster binding
BBEV_2212	COG0243	molybdopterin cofactor binding
BBEV_2213	COG3381	protein complex oligomerization
BBEV_2214	COG0437	4 iron, 4 sulfur cluster binding
BBEV_2215	COG0243	molybdopterin cofactor binding
BBEV_2216	COG2508	Transcriptional regulator
BBEV_2219	COG0579	oxidoreductase
BBEV_2228	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBEV_2229	COG2311	Membrane
BBEV_2235	COG1131	(ABC) transporter
BBEV_2238	COG0450	alkyl hydroperoxide reductase
BBEV_2241	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBEV_2242	COG2022	thiamine diphosphate biosynthetic process
BBEV_2244	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBEV_2245	COG0352	thiamine-phosphate diphosphorylase activity
BBEV_2246	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBEV_2248	COG0419	ATPase involved in DNA repair
BBEV_2249	COG0420	3'-5' exonuclease activity
BBEV_2250	COG4221	oxidoreductase activity
BBEV_2252	COG3835	regulator
BBEV_2253	COG0243	molybdopterin cofactor binding
BBEV_2257	COG0437	4 iron, 4 sulfur cluster binding
BBEV_2258	COG0243	molybdopterin cofactor binding
BBEV_2261	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBEV_2262	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBEV_2265	COG0726	polysaccharide deacetylase
BBEV_2285	COG0735	belongs to the Fur family
BBEV_2290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBEV_2291	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBEV_2292	COG0067	glutamate synthase
BBEV_2292	COG0070	glutamate synthase
BBEV_2292	COG0069	glutamate synthase activity
BBEV_2293	COG4129	membrane
BBEV_2295	COG1132	(ABC) transporter
BBEV_2296	COG3557	Belongs to the UPF0374 family
BBEV_2301	COG0745	RESPONSE REGULATOR receiver
BBEV_2302	COG2059	Chromate
BBEV_2303	COG2059	Chromate
BBEV_2305	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2306	COG1194	a g-specific adenine glycosylase
BBEV_2307	COG1988	membrane-bound metal-dependent
BBEV_2310	COG2137	regulation of response to DNA damage stimulus
BBEV_2311	COG1090	epimerase
BBEV_2313	COG2188	Transcriptional regulator
BBEV_2318	COG0492	ferredoxin-NADP+ reductase activity
BBEV_2323	COG0601	transmembrane transport
BBEV_2326	COG1151	hydroxylamine reductase activity
BBEV_2330	COG0298	carbon dioxide binding
BBEV_2331	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BBEV_2332	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBEV_2333	COG0375	protein maturation
BBEV_2336	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BBEV_2339	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_2344	COG0535	radical SAM domain protein
BBEV_2345	COG0534	Mate efflux family protein
BBEV_2346	COG0477	Major facilitator Superfamily
BBEV_2353	COG1254	Belongs to the acylphosphatase family
BBEV_2357	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_2359	COG2226	methyltransferase
BBEV_2360	COG0288	reversible hydration of carbon dioxide
BBEV_2361	COG0425	Belongs to the sulfur carrier protein TusA family
BBEV_2362	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2362	COG0425	Belongs to the sulfur carrier protein TusA family
BBEV_2364	COG0628	permease
BBEV_2368	COG0488	(ABC) transporter
BBEV_2370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBEV_2371	COG0400	carboxylic ester hydrolase activity
BBEV_2372	COG0514	ATP-dependent DNA helicase (RecQ)
BBEV_2373	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_2374	COG1937	Protein conserved in bacteria
BBEV_2375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BBEV_2376	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BBEV_2379	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBEV_2380	COG1132	(ABC) transporter
BBEV_2381	COG1132	(ABC) transporter
BBEV_2382	COG1929	Belongs to the glycerate kinase type-1 family
BBEV_2383	COG0366	Alpha amylase catalytic
BBEV_2384	COG2962	Rard protein
BBEV_2386	COG2801	Transposase and inactivated derivatives
BBEV_2387	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2391	COG4895	conserved protein (DUF2196)
BBEV_2392	COG5001	Diguanylate cyclase
BBEV_2392	COG3447	MASE1 domain protein
BBEV_2392	COG5002	protein histidine kinase activity
BBEV_2395	COG1554	hydrolase, family 65, central catalytic
BBEV_2396	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2397	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBEV_2398	COG4605	iron ion homeostasis
BBEV_2399	COG4604	ABC transporter, ATP-binding protein
BBEV_2400	COG4607	ABC-type enterochelin transport system periplasmic component
BBEV_2401	COG0194	GDP metabolic process
BBEV_2403	COG1070	Carbohydrate kinase
BBEV_2404	COG2115	Belongs to the xylose isomerase family
BBEV_2405	COG1940	carbohydrate kinase activity
BBEV_2406	COG2207	Transcriptional regulator
BBEV_2406	COG1917	Cupin 2, conserved barrel domain protein
BBEV_2407	COG2972	Histidine kinase
BBEV_2408	COG4753	response regulator
BBEV_2408	COG2207	Transcriptional regulator
BBEV_2409	COG1653	transport
BBEV_2412	COG3507	Belongs to the glycosyl hydrolase 43 family
BBEV_2413	COG5578	integral membrane protein
BBEV_2417	COG5487	UPF0391 membrane protein
BBEV_2418	COG5487	UPF0391 membrane protein
BBEV_2420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBEV_2421	COG1388	LysM domain
BBEV_2421	COG3584	3D domain protein
BBEV_2424	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBEV_2425	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_2425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBEV_2427	COG3386	PFAM SMP-30 Gluconolaconase
BBEV_2428	COG2814	Major facilitator Superfamily
BBEV_2431	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBEV_2432	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBEV_2432	COG2755	lipolytic protein G-D-S-L family
BBEV_2434	COG2391	methyltransferase activity
BBEV_2437	COG2897	thiosulfate sulfurtransferase activity
BBEV_2439	COG0840	transmembrane signaling receptor activity
BBEV_2441	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBEV_2442	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBEV_2446	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBEV_2451	COG1940	carbohydrate kinase activity
BBEV_2453	COG3973	AAA domain
BBEV_2454	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBEV_2458	COG4372	Transposase
BBEV_2462	COG1309	transcriptional regulator
BBEV_2469	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_2474	COG3850	Histidine kinase
BBEV_2475	COG1960	acyl-CoA dehydrogenase activity
BBEV_2480	COG1309	transcriptional regulator
BBEV_2481	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBEV_2482	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBEV_2483	COG1120	ATPase activity
BBEV_2484	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BBEV_2487	COG0406	alpha-ribazole phosphatase activity
BBEV_2490	COG2217	Heavy metal translocating P-type atpase
BBEV_2492	COG5001	Diguanylate cyclase
BBEV_2492	COG5002	protein histidine kinase activity
BBEV_2492	COG3447	MASE1 domain protein
BBEV_2495	COG0431	NADPH-dependent FMN reductase
BBEV_2497	COG1733	regulation of RNA biosynthetic process
BBEV_2499	COG3842	ATPase activity
BBEV_2502	COG1910	domain protein
BBEV_2503	COG2346	COG2346, Truncated hemoglobins
BBEV_2504	COG2070	2-Nitropropane dioxygenase
BBEV_2506	COG0667	Aldo Keto reductase
BBEV_2507	COG0561	phosphatase activity
BBEV_2509	COG2514	catechol 2,3-dioxygenase activity
BBEV_2510	COG1966	Carbon starvation protein
BBEV_2511	COG3279	Response regulator of the LytR AlgR family
BBEV_2512	COG3275	phosphorelay sensor kinase activity
BBEV_2521	COG0455	bacterial-type flagellum organization
BBEV_2528	COG0456	acetyltransferase
BBEV_2541	COG3177	Filamentation induced by cAMP protein fic
BBEV_2546	COG4372	Transposase
BBEV_2552	COG1404	Belongs to the peptidase S8 family
BBEV_2557	COG4372	Transposase
BBEV_2558	COG3547	Transposase (IS116 IS110 IS902 family)
BBEV_2565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_2569	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBEV_2573	COG0640	Transcriptional regulator
BBEV_2575	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBEV_2578	COG1597	lipid kinase activity
BBEV_2580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBEV_2581	COG0154	amidase activity
BBEV_2582	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBEV_2583	COG4851	CamS sex pheromone cAM373 precursor
BBEV_2584	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBEV_2585	COG0210	DNA helicase
BBEV_2586	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BBEV_2587	COG0840	transmembrane signaling receptor activity
BBEV_2588	COG0494	nUDIX hydrolase
BBEV_2592	COG2124	cytochrome p450
BBEV_2594	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBEV_2596	COG0523	cobalamin synthesis protein
BBEV_2599	COG0400	carboxylic ester hydrolase activity
BBEV_2600	COG0346	lactoylglutathione lyase activity
BBEV_2602	COG4496	protein, YerC YecD
BBEV_2603	COG1470	cell adhesion involved in biofilm formation
BBEV_2604	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBEV_2606	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBEV_2607	COG0405	Gamma-glutamyltransferase
BBEV_2608	COG0492	ferredoxin-NADP+ reductase activity
BBEV_2609	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBEV_2611	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBEV_2613	COG3639	organic phosphonate transmembrane transporter activity
BBEV_2619	COG0110	maltose O-acetyltransferase activity
BBEV_2620	COG0151	Belongs to the GarS family
BBEV_2621	COG0138	bifunctional purine biosynthesis protein purh
BBEV_2622	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBEV_2624	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBEV_2625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBEV_2626	COG0047	phosphoribosylformylglycinamidine synthase activity
BBEV_2627	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBEV_2628	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BBEV_2629	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBEV_2630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBEV_2631	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBEV_2634	COG0542	response to heat
BBEV_2636	COG5002	protein histidine kinase activity
BBEV_2639	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBEV_2641	COG2252	PERMEase
BBEV_2642	COG0519	Catalyzes the synthesis of GMP from XMP
BBEV_2642	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBEV_2643	COG1305	Transglutaminase-like
BBEV_2644	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BBEV_2645	COG0714	Associated with various cellular activities
BBEV_2648	COG0778	Nitroreductase
BBEV_2649	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_2650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBEV_2651	COG4988	ABC transporter
BBEV_2659	COG1132	(ABC) transporter
BBEV_2660	COG0745	RESPONSE REGULATOR receiver
BBEV_2661	COG5002	protein histidine kinase activity
BBEV_2661	COG3850	Histidine kinase
BBEV_2666	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_2666	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2667	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BBEV_2670	COG1454	alcohol dehydrogenase
BBEV_2671	COG2133	pyrroloquinoline quinone binding
BBEV_2672	COG1827	regulation of RNA biosynthetic process
BBEV_2673	COG1104	cysteine desulfurase activity
BBEV_2674	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBEV_2675	COG0157	Belongs to the NadC ModD family
BBEV_2676	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBEV_2677	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBEV_2678	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBEV_2679	COG1215	transferase activity, transferring glycosyl groups
BBEV_2686	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BBEV_2688	COG2351	hydroxyisourate hydrolase activity
BBEV_2690	COG3195	allantoin biosynthetic process
BBEV_2690	COG3648	Uricase
BBEV_2691	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_2692	COG0746	molybdenum cofactor guanylyltransferase activity
BBEV_2693	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBEV_2694	COG2080	2 iron, 2 sulfur cluster binding
BBEV_2695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBEV_2696	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BBEV_2697	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_2698	COG0154	amidase activity
BBEV_2701	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_2702	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_2705	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_2706	COG2508	Transcriptional regulator
BBEV_2708	COG0737	Belongs to the 5'-nucleotidase family
BBEV_2712	COG3437	response regulator, receiver
BBEV_2712	COG2770	Histidine kinase
BBEV_2715	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBEV_2717	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBEV_2720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_2721	COG1053	succinate dehydrogenase
BBEV_2722	COG2009	succinate dehydrogenase
BBEV_2723	COG1027	Aspartate ammonia-lyase
BBEV_2726	COG4191	Histidine kinase
BBEV_2727	COG0784	Response regulator, receiver
BBEV_2730	COG2972	Histidine kinase
BBEV_2730	COG0745	RESPONSE REGULATOR receiver
BBEV_2733	COG3284	Transcriptional regulator
BBEV_2734	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBEV_2735	COG0022	dehydrogenase e1 component
BBEV_2736	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_2737	COG1063	alcohol dehydrogenase
BBEV_2738	COG0415	Belongs to the DNA photolyase family
BBEV_2740	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_2744	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_2747	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_2748	COG0783	Belongs to the Dps family
BBEV_2749	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2751	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBEV_2754	COG0471	metal ion transport
BBEV_2761	COG0702	epimerase
BBEV_2762	COG0346	lactoylglutathione lyase activity
BBEV_2763	COG0667	Aldo Keto reductase
BBEV_2764	COG0459	protein refolding
BBEV_2765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBEV_2768	COG0243	molybdopterin cofactor binding
BBEV_2775	COG2814	Major facilitator Superfamily
BBEV_2776	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBEV_2778	COG0488	(ABC) transporter
BBEV_2779	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBEV_2780	COG0456	acetyltransferase
BBEV_2781	COG1214	PFAM Peptidase M22, glycoprotease
BBEV_2782	COG0802	atpase or kinase
BBEV_2783	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BBEV_2784	COG0626	cystathionine gamma-synthase activity
BBEV_2785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBEV_2786	COG4988	ABC transporter
BBEV_2787	COG1294	oxidase, subunit
BBEV_2788	COG1271	oxidase subunit
BBEV_2801	COG3091	SprT-like family
BBEV_2802	COG2183	response to ionizing radiation
BBEV_2804	COG1191	sigma factor activity
BBEV_2805	COG2172	sigma factor antagonist activity
BBEV_2806	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_2807	COG2208	phosphoserine phosphatase activity
BBEV_2808	COG2172	sigma factor antagonist activity
BBEV_2809	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_2810	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_2811	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBEV_2813	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBEV_2814	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBEV_2814	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBEV_2816	COG0705	Rhomboid family
BBEV_2817	COG1178	ABC-type Fe3 transport system permease component
BBEV_2819	COG3842	ATPase activity
BBEV_2821	COG0506	proline dehydrogenase activity
BBEV_2822	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBEV_2823	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_2824	COG3829	transcription factor binding
BBEV_2827	COG1595	DNA-templated transcription, initiation
BBEV_2830	COG5001	Diguanylate cyclase
BBEV_2830	COG3300	MHYT domain
BBEV_2834	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_2835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBEV_2836	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBEV_2837	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBEV_2837	COG1263	PTS System
BBEV_2838	COG1609	Transcriptional regulator
BBEV_2839	COG1278	Cold shock
BBEV_2841	COG0659	secondary active sulfate transmembrane transporter activity
BBEV_2842	COG0589	response to stress
BBEV_2843	COG2226	methyltransferase
BBEV_2844	COG0534	Mate efflux family protein
BBEV_2846	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_2846	COG2202	Pas domain
BBEV_2847	COG0640	Transcriptional regulator
BBEV_2848	COG2239	Acts as a magnesium transporter
BBEV_2851	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBEV_2852	COG0765	amino acid transport
BBEV_2855	COG1227	inorganic diphosphatase activity
BBEV_2856	COG0646	methionine synthase
BBEV_2856	COG1410	methionine synthase
BBEV_2857	COG0646	methionine synthase
BBEV_2857	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBEV_2858	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBEV_2858	COG0646	methionine synthase
BBEV_2859	COG0626	cystathionine gamma-synthase activity
BBEV_2860	COG0626	cystathionine gamma-synthase activity
BBEV_2864	COG1247	-acetyltransferase
BBEV_2865	COG0477	Major facilitator Superfamily
BBEV_2866	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BBEV_2867	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBEV_2873	COG1131	(ABC) transporter
BBEV_2874	COG2188	Transcriptional regulator
BBEV_2876	COG0398	Pfam SNARE associated Golgi protein
BBEV_2879	COG0604	alcohol dehydrogenase
BBEV_2880	COG2860	membrane
BBEV_2883	COG1272	protein, Hemolysin III
BBEV_2884	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBEV_2886	COG0745	RESPONSE REGULATOR receiver
BBEV_2886	COG3706	GGDEF domain
BBEV_2887	COG1234	tRNA 3'-trailer cleavage
BBEV_2888	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_2890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_2894	COG4989	oxidoreductase activity
BBEV_2895	COG0501	Belongs to the peptidase M48B family
BBEV_2898	COG0655	NAD(P)H dehydrogenase (quinone) activity
BBEV_2900	COG1846	Transcriptional regulator
BBEV_2901	COG0346	lactoylglutathione lyase activity
BBEV_2902	COG0398	Pfam SNARE associated Golgi protein
BBEV_2905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BBEV_2906	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBEV_2907	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBEV_2909	COG1609	Transcriptional regulator
BBEV_2913	COG1653	transport
BBEV_2915	COG1704	LemA family
BBEV_2916	COG0501	Belongs to the peptidase M48B family
BBEV_2917	COG1846	Transcriptional regulator
BBEV_2922	COG0739	heme binding
BBEV_2922	COG0741	lytic transglycosylase activity
BBEV_2922	COG1196	nuclear chromosome segregation
BBEV_2923	COG0745	RESPONSE REGULATOR receiver
BBEV_2924	COG1388	LysM domain
BBEV_2924	COG0791	NLP P60 protein
BBEV_2925	COG1874	Beta-galactosidase
BBEV_2927	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_2929	COG1595	DNA-templated transcription, initiation
BBEV_2933	COG2135	peptidase activity
BBEV_2934	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBEV_2937	COG2409	Drug exporters of the RND superfamily
BBEV_2939	COG0295	cytidine deaminase activity
BBEV_2945	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BBEV_2948	COG3711	transcriptional antiterminator
BBEV_2949	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_2950	COG0246	Mannitol dehydrogenase
BBEV_2953	COG3173	Aminoglycoside phosphotransferase
BBEV_2956	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBEV_2957	COG0427	acetyl-CoA hydrolase
BBEV_2958	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBEV_2959	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBEV_2962	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_2964	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBEV_2965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBEV_2966	COG4856	YbbR-like protein
BBEV_2967	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBEV_2968	COG5662	AntiSigma factor
BBEV_2969	COG1595	DNA-templated transcription, initiation
BBEV_2975	COG2194	sulfuric ester hydrolase activity
BBEV_2976	COG0489	protein tyrosine kinase activity
BBEV_2977	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BBEV_2979	COG0667	Aldo Keto reductase
BBEV_2982	COG0726	polysaccharide deacetylase
BBEV_2983	COG1132	(ABC) transporter
BBEV_2984	COG1132	(ABC) transporter
BBEV_2988	COG1510	regulation of RNA biosynthetic process
BBEV_2989	COG4175	Glycine betaine
BBEV_2989	COG0517	IMP dehydrogenase activity
BBEV_2992	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBEV_2996	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_2998	COG0371	Dehydrogenase
BBEV_2999	COG1609	Transcriptional regulator
BBEV_3000	COG2160	L-arabinose isomerase activity
BBEV_3001	COG1069	ribulokinase activity
BBEV_3003	COG1653	transport
BBEV_3004	COG1175	transmembrane transport
BBEV_3005	COG0395	ABC-type sugar transport system, permease component
BBEV_3007	COG3534	alpha-L-arabinofuranosidase
BBEV_3009	COG4149	molybdate abc transporter
BBEV_3010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBEV_3014	COG0395	ABC-type sugar transport system, permease component
BBEV_3016	COG1653	transport
BBEV_3017	COG5578	integral membrane protein
BBEV_3018	COG1609	Transcriptional regulator
BBEV_3020	COG1940	carbohydrate kinase activity
BBEV_3022	COG1595	DNA-templated transcription, initiation
BBEV_3024	COG5002	protein histidine kinase activity
BBEV_3028	COG1737	Transcriptional regulator
BBEV_3029	COG1653	transport
BBEV_3030	COG1486	melibiose metabolic process
BBEV_3031	COG1714	RDD family
BBEV_3032	COG2814	Major facilitator Superfamily
BBEV_3037	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBEV_3039	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_3040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_3041	COG0716	FMN binding
BBEV_3042	COG1328	CTP reductase activity
BBEV_3045	COG0395	ABC-type sugar transport system, permease component
BBEV_3047	COG1653	transport
BBEV_3050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBEV_3051	COG2267	carboxylic ester hydrolase activity
BBEV_3056	COG4585	Histidine kinase
BBEV_3057	COG2197	response regulator
BBEV_3060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBEV_3061	COG0386	Belongs to the glutathione peroxidase family
BBEV_3068	COG0673	inositol 2-dehydrogenase activity
BBEV_3069	COG1082	Xylose isomerase domain protein TIM barrel
BBEV_3070	COG0673	inositol 2-dehydrogenase activity
BBEV_3074	COG3976	FMN-binding domain protein
BBEV_3074	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BBEV_3075	COG0574	Belongs to the PEP-utilizing enzyme family
BBEV_3075	COG3848	Pyruvate phosphate dikinase
BBEV_3076	COG1309	transcriptional regulator
BBEV_3077	COG3447	MASE1 domain protein
BBEV_3077	COG5001	Diguanylate cyclase
BBEV_3077	COG5002	protein histidine kinase activity
BBEV_3079	COG1595	DNA-templated transcription, initiation
BBEV_3082	COG2226	methyltransferase
BBEV_3083	COG1595	DNA-templated transcription, initiation
BBEV_3086	COG1131	(ABC) transporter
BBEV_3092	COG0596	Alpha beta hydrolase
BBEV_3093	COG0596	Alpha beta hydrolase
BBEV_3098	COG3394	polysaccharide catabolic process
BBEV_3099	COG1486	melibiose metabolic process
BBEV_3100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBEV_3101	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBEV_3102	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBEV_3103	COG4372	Transposase
BBEV_3107	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBEV_3109	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBEV_3110	COG0577	efflux transmembrane transporter activity
BBEV_3110	COG1136	(ABC) transporter
BBEV_3126	COG3177	Filamentation induced by cAMP protein fic
BBEV_3129	COG1278	Cold shock
BBEV_3130	COG3654	unkown
BBEV_3135	COG0071	Belongs to the small heat shock protein (HSP20) family
BBEV_3148	COG3706	GGDEF domain
BBEV_3154	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_3156	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBEV_3161	COG2130	NADP-dependent
BBEV_3166	COG1247	-acetyltransferase
BBEV_3170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_3170	COG3711	transcriptional antiterminator
BBEV_3171	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_3173	COG3037	sugar-specific permease SgaT UlaA
BBEV_3174	COG0159	tryptophan synthase activity
BBEV_3176	COG1737	Transcriptional regulator
BBEV_3177	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BBEV_3178	COG3876	Protein conserved in bacteria
BBEV_3179	COG1486	melibiose metabolic process
BBEV_3180	COG2971	BadF BadG BcrA BcrD
BBEV_3181	COG0395	ABC-type sugar transport system, permease component
BBEV_3182	COG1175	transmembrane transport
BBEV_3185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBEV_3188	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBEV_3189	COG0363	glucosamine-6-phosphate deaminase activity
BBEV_3191	COG4821	SIS domain
BBEV_3194	COG2239	Acts as a magnesium transporter
BBEV_3198	COG1510	regulation of RNA biosynthetic process
BBEV_3200	COG3290	protein histidine kinase activity
BBEV_3200	COG3829	transcription factor binding
BBEV_3204	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_3205	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BBEV_3206	COG0385	Bile acid
BBEV_3207	COG0415	Belongs to the DNA photolyase family
BBEV_3208	COG1876	peptidase activity
BBEV_3209	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBEV_3210	COG0367	asparagine synthase
BBEV_3211	COG1902	pentaerythritol trinitrate reductase activity
BBEV_3212	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BBEV_3213	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBEV_3214	COG0101	tRNA pseudouridine synthase activity
BBEV_3215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBEV_3217	COG1122	ATPase activity
BBEV_3218	COG0203	ribosomal protein L17
BBEV_3219	COG0202	RNA polymerase activity
BBEV_3220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBEV_3221	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBEV_3222	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBEV_3223	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BBEV_3224	COG0024	Methionine aminopeptidase
BBEV_3225	COG0563	adenylate kinase activity
BBEV_3226	COG0200	Binds to the 23S rRNA
BBEV_3227	COG1841	ribosomal large subunit assembly
BBEV_3229	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBEV_3230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBEV_3231	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBEV_3232	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBEV_3233	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBEV_3234	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBEV_3235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBEV_3236	COG0255	Belongs to the universal ribosomal protein uL29 family
BBEV_3237	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBEV_3238	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBEV_3239	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBEV_3240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBEV_3241	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBEV_3242	COG0089	rRNA binding
BBEV_3243	COG0088	Forms part of the polypeptide exit tunnel
BBEV_3244	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBEV_3245	COG0051	transcription antitermination factor activity, RNA binding
BBEV_3248	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBEV_3249	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBEV_3250	COG0049	tRNA binding
BBEV_3251	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBEV_3252	COG1358	cellular component organization or biogenesis
BBEV_3253	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBEV_3254	COG0085	RNA polymerase activity
BBEV_3256	COG0222	ribosome binding
BBEV_3258	COG0081	regulation of translation
BBEV_3259	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBEV_3260	COG0250	Participates in transcription elongation, termination and antitermination
BBEV_3261	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBEV_3262	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBEV_3264	COG1595	DNA-templated transcription, initiation
BBEV_3266	COG3688	RNA-binding protein containing a PIN domain
BBEV_3267	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBEV_3269	COG0215	cysteine-tRNA ligase activity
BBEV_3270	COG1045	serine acetyltransferase
BBEV_3271	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBEV_3273	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBEV_3274	COG4956	integral membrane protein (PIN domain superfamily)
BBEV_3275	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BBEV_3276	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBEV_3277	COG0542	response to heat
BBEV_3278	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BBEV_3279	COG3880	PFAM UvrB UvrC protein
BBEV_3281	COG1285	pathogenesis
BBEV_3283	COG0716	FMN binding
BBEV_3301	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBEV_3302	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBEV_3303	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBEV_3304	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBEV_3305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBEV_3306	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_3307	COG0512	Glutamine amidotransferase of anthranilate synthase
BBEV_3308	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBEV_3310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBEV_3311	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBEV_3314	COG0037	tRNA processing
BBEV_3317	COG1098	S1 RNA binding domain
BBEV_3319	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BBEV_3320	COG3956	TIGRFAM MazG family protein
BBEV_3321	COG2244	polysaccharide biosynthetic process
BBEV_3322	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBEV_3323	COG0193	aminoacyl-tRNA hydrolase activity
BBEV_3324	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBEV_3325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBEV_3326	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBEV_3327	COG2088	sporulation resulting in formation of a cellular spore
BBEV_3328	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBEV_3329	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBEV_3330	COG4466	Protein conserved in bacteria
BBEV_3331	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBEV_3332	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBEV_3333	COG3584	3D domain protein
BBEV_3333	COG3583	domain protein
BBEV_3334	COG0084	hydrolase, TatD family'
BBEV_3335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_3335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_3337	COG2002	toxin-antitoxin pair type II binding
BBEV_3338	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBEV_3339	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBEV_3341	COG1774	PSP1 C-terminal conserved region
BBEV_3342	COG0470	DNA polymerase III
BBEV_3343	COG3870	Protein conserved in bacteria
BBEV_3344	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBEV_3345	COG1982	Orn Lys Arg decarboxylase major
BBEV_3349	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBEV_3355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBEV_3356	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBEV_3357	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBEV_3360	COG0590	tRNA wobble adenosine to inosine editing
BBEV_3361	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_3362	COG0601	transmembrane transport
BBEV_3364	COG4608	Belongs to the ABC transporter superfamily
BBEV_3365	COG0444	Belongs to the ABC transporter superfamily
BBEV_3367	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBEV_3368	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBEV_3371	COG0517	IMP dehydrogenase activity
BBEV_3371	COG0516	GMP reductase activity
BBEV_3378	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBEV_3379	COG0187	DNA topoisomerase II activity