locus-tag	class	description
CY96_00020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CY96_00025	COG4856	YbbR-like protein
CY96_00065	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_00070	COG2011	ABC-type metal ion transport system permease component
CY96_00075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CY96_00080	COG1464	Belongs to the NlpA lipoprotein family
CY96_00085	COG0604	alcohol dehydrogenase
CY96_00095	COG0277	FAD linked oxidase domain protein
CY96_00100	COG2271	Major facilitator Superfamily
CY96_00110	COG2814	Major facilitator Superfamily
CY96_00125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY96_00130	COG0444	Belongs to the ABC transporter superfamily
CY96_00135	COG4608	Belongs to the ABC transporter superfamily
CY96_00140	COG4166	transmembrane transport
CY96_00150	COG2207	Transcriptional regulator
CY96_00165	COG4166	transmembrane transport
CY96_00170	COG4166	transmembrane transport
CY96_00175	COG0656	L-ascorbic acid biosynthetic process
CY96_00190	COG4149	molybdate abc transporter
CY96_00195	COG0725	ABC transporter, periplasmic molybdate-binding protein
CY96_00200	COG1910	domain protein
CY96_00220	COG0697	spore germination
CY96_00235	COG0204	Acyl-transferase
CY96_00250	COG1609	Transcriptional regulator
CY96_00260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_00285	COG5298	Protein conserved in bacteria
CY96_00305	COG0488	(ABC) transporter
CY96_00315	COG0747	negative chemotaxis
CY96_00320	COG0601	transmembrane transport
CY96_00330	COG0444	Belongs to the ABC transporter superfamily
CY96_00335	COG4608	Belongs to the ABC transporter superfamily
CY96_00340	COG0561	phosphatase activity
CY96_00375	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CY96_00380	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY96_00390	COG0531	amino acid
CY96_00395	COG2814	Major facilitator Superfamily
CY96_00405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CY96_00415	COG4294	response to UV
CY96_00420	COG0705	Rhomboid family
CY96_00430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CY96_00435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY96_00440	COG0864	Transcriptional regulator
CY96_00445	COG2337	Toxic component of a toxin-antitoxin (TA) module
CY96_00450	COG2183	response to ionizing radiation
CY96_00550	COG0802	atpase or kinase
CY96_00555	COG1214	PFAM Peptidase M22, glycoprotease
CY96_00560	COG0456	acetyltransferase
CY96_00570	COG0488	(ABC) transporter
CY96_00585	COG1266	CAAX protease self-immunity
CY96_00605	COG2252	PERMEase
CY96_00615	COG5002	protein histidine kinase activity
CY96_00640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CY96_00680	COG2205	protein histidine kinase activity
CY96_00685	COG0745	RESPONSE REGULATOR receiver
CY96_00720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY96_00730	COG1216	Glycosyl transferase, family 2
CY96_00730	COG0463	Glycosyl transferase, family 2
CY96_00750	COG0697	spore germination
CY96_00780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CY96_00785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CY96_00790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CY96_00800	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CY96_00815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CY96_00825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CY96_00835	COG0151	Belongs to the GarS family
CY96_00860	COG0210	DNA helicase
CY96_00870	COG4851	CamS sex pheromone cAM373 precursor
CY96_00885	COG1335	isochorismatase
CY96_00895	COG2011	ABC-type metal ion transport system permease component
CY96_00900	COG1464	Belongs to the NlpA lipoprotein family
CY96_00910	COG0003	Pfam Anion-transporting ATPase
CY96_00915	COG1846	Transcriptional regulator
CY96_00920	COG4682	membrane
CY96_00940	COG1597	lipid kinase activity
CY96_00950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CY96_00960	COG1012	belongs to the aldehyde dehydrogenase family
CY96_00965	COG2076	Multidrug Resistance protein
CY96_00975	COG2309	aminopeptidase activity
CY96_00995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_01005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY96_01010	COG4807	Protein conserved in bacteria
CY96_01040	COG1473	amidohydrolase
CY96_01055	COG0450	alkyl hydroperoxide reductase
CY96_01060	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CY96_01070	COG0235	Class ii aldolase
CY96_01075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_01080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_01085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_01100	COG0166	Belongs to the GPI family
CY96_01130	COG5002	protein histidine kinase activity
CY96_01150	COG3541	Predicted nucleotidyltransferase
CY96_01155	COG2814	Major facilitator Superfamily
CY96_01160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY96_01160	COG0723	plastoquinol--plastocyanin reductase activity
CY96_01170	COG0765	amino acid transport
CY96_01175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY96_01185	COG0840	transmembrane signaling receptor activity
CY96_01210	COG0549	Belongs to the carbamate kinase family
CY96_01215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY96_01225	COG0277	FAD linked oxidase domain protein
CY96_01230	COG0366	Alpha amylase catalytic
CY96_01235	COG1263	PTS System
CY96_01235	COG2190	(PTS) system
CY96_01235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_01265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CY96_01285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY96_01290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY96_01295	COG1116	anion transmembrane transporter activity
CY96_01340	COG2270	Major facilitator Superfamily
CY96_01370	COG2310	stress, protein
CY96_01375	COG2310	stress, protein
CY96_01380	COG2310	stress, protein
CY96_01385	COG0861	Integral membrane protein TerC family
CY96_01395	COG3853	Toxic anion resistance protein (TelA)
CY96_01410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CY96_01420	COG1295	ribonuclease BN
CY96_01425	COG2217	Heavy metal translocating P-type atpase
CY96_01430	COG0697	spore germination
CY96_01440	COG0681	Belongs to the peptidase S26 family
CY96_01450	COG0586	Pfam SNARE associated Golgi protein
CY96_01465	COG3871	stress protein (general stress protein 26)
CY96_01470	COG0387	Pfam Sodium calcium exchanger
CY96_01480	COG0535	radical SAM domain protein
CY96_01500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CY96_01505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CY96_01520	COG3829	transcription factor binding
CY96_01530	COG0833	amino acid
CY96_01535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CY96_01565	COG1263	PTS System
CY96_01565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_01570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY96_01585	COG0463	Glycosyl transferase, family 2
CY96_01595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY96_01595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CY96_01615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CY96_01635	COG1228	amidohydrolase
CY96_01640	COG1090	epimerase
CY96_01670	COG1988	membrane-bound metal-dependent
CY96_01675	COG1194	a g-specific adenine glycosylase
CY96_01700	COG1132	(ABC) transporter
CY96_01705	COG4129	membrane
CY96_01710	COG0069	glutamate synthase activity
CY96_01710	COG0067	glutamate synthase
CY96_01710	COG0070	glutamate synthase
CY96_01720	COG4555	ABC transporter
CY96_01740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CY96_01745	COG0735	belongs to the Fur family
CY96_01860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CY96_01885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CY96_01890	COG1716	ATPase activity
CY96_01890	COG5001	Diguanylate cyclase
CY96_01900	COG2766	serine protein kinase
CY96_01920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY96_01930	COG1585	Membrane protein implicated in regulation of membrane protease activity
CY96_01935	COG2268	Band 7 protein
CY96_01945	COG3290	protein histidine kinase activity
CY96_01950	COG4565	transcriptional regulatory protein
CY96_01955	COG2851	Citrate transporter
CY96_01980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CY96_01985	COG3842	ATPase activity
CY96_01990	COG1175	transmembrane transport
CY96_01995	COG0395	ABC-type sugar transport system, permease component
CY96_02010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CY96_02015	COG0745	RESPONSE REGULATOR receiver
CY96_02020	COG5002	protein histidine kinase activity
CY96_02030	COG4990	cell redox homeostasis
CY96_02040	COG3290	protein histidine kinase activity
CY96_02045	COG4565	transcriptional regulatory protein
CY96_02050	COG3493	citrate carrier protein
CY96_02055	COG0281	malic enzyme
CY96_02070	COG0697	spore germination
CY96_02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_02085	COG5002	protein histidine kinase activity
CY96_02090	COG0745	RESPONSE REGULATOR receiver
CY96_02105	COG0456	acetyltransferase
CY96_02105	COG0454	-acetyltransferase
CY96_02110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CY96_02115	COG3383	formate dehydrogenase (NAD+) activity
CY96_02120	COG2427	Protein of unknown function (DUF1641)
CY96_02135	COG0531	amino acid
CY96_02145	COG0640	Transcriptional regulator
CY96_02150	COG2217	Heavy metal translocating P-type atpase
CY96_02155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CY96_02170	COG3227	Zinc metalloprotease (Elastase)
CY96_02190	COG2720	vancomycin resistance protein
CY96_02195	COG1316	TRANSCRIPTIONal
CY96_02200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_02205	COG0346	lactoylglutathione lyase activity
CY96_02210	COG1253	flavin adenine dinucleotide binding
CY96_02215	COG1027	Aspartate ammonia-lyase
CY96_02220	COG1620	l-lactate permease
CY96_02235	COG3104	oligopeptide transport
CY96_02240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_02245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_02250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_02260	COG2226	methyltransferase
CY96_02270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY96_02280	COG4548	von Willebrand factor, type A
CY96_02285	COG0714	Associated with various cellular activities
CY96_02305	COG0531	amino acid
CY96_02310	COG2188	Transcriptional regulator
CY96_02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_02315	COG1263	PTS System
CY96_02320	COG0366	Alpha amylase catalytic
CY96_02335	COG0697	spore germination
CY96_02340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY96_02345	COG1115	amino acid carrier protein
CY96_02355	COG1126	abc transporter atp-binding protein
CY96_02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY96_02365	COG0765	amino acid transport
CY96_02370	COG0765	amino acid transport
CY96_02375	COG0833	amino acid
CY96_02390	COG2378	regulation of single-species biofilm formation
CY96_02395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CY96_02400	COG5002	protein histidine kinase activity
CY96_02425	COG0659	secondary active sulfate transmembrane transporter activity
CY96_02440	COG2271	Major facilitator Superfamily
CY96_02445	COG1846	Transcriptional regulator
CY96_02450	COG0477	Major facilitator Superfamily
CY96_02455	COG1609	Transcriptional regulator
CY96_02460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY96_02475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY96_02480	COG1879	ABC-type sugar transport system periplasmic component
CY96_02505	COG1063	alcohol dehydrogenase
CY96_02555	COG0840	transmembrane signaling receptor activity
CY96_02560	COG1388	LysM domain
CY96_02560	COG3584	3D domain protein
CY96_02565	COG1476	TRANSCRIPTIONal
CY96_02585	COG3104	oligopeptide transport
CY96_02595	COG1114	Component of the transport system for branched-chain amino acids
CY96_02610	COG1113	amino acid transport
CY96_02615	COG2252	PERMEase
CY96_02630	COG2153	protein acetylation
CY96_02640	COG0569	domain protein
CY96_02640	COG0475	glutathione-regulated potassium exporter activity
CY96_02650	COG1845	cytochrome c oxidase, subunit III
CY96_02655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CY96_02675	COG4990	cell redox homeostasis
CY96_02690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY96_02695	COG0697	spore germination
CY96_02700	COG0531	amino acid
CY96_02715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CY96_02720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CY96_02725	COG1918	ferrous iron import across plasma membrane
CY96_02725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CY96_02730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CY96_02735	COG0573	inorganic phosphate transmembrane transporter activity
CY96_02740	COG0581	inorganic phosphate transmembrane transporter activity
CY96_02745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY96_02780	COG0544	peptidyl-prolyl cis-trans isomerase activity
CY96_02860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CY96_02880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CY96_02885	COG1116	anion transmembrane transporter activity
CY96_02890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY96_02895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY96_02900	COG0352	thiamine-phosphate diphosphorylase activity
CY96_02905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY96_02910	COG2104	thiamine diphosphate biosynthetic process
CY96_02920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY96_02925	COG0351	phosphomethylpyrimidine kinase
CY96_02965	COG2205	protein histidine kinase activity
CY96_02970	COG2814	Major facilitator Superfamily
CY96_02975	COG1846	Transcriptional regulator
CY96_02995	COG2252	PERMEase
CY96_03000	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_03015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY96_03020	COG1621	beta-fructofuranosidase activity
CY96_03025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_03025	COG1263	PTS System
CY96_03030	COG1609	Transcriptional regulator
CY96_03080	COG0778	Nitroreductase
CY96_03085	COG2719	SpoVR family
CY96_03095	COG3591	Belongs to the peptidase S1B family
CY96_03100	COG0446	pyridine nucleotide-disulphide oxidoreductase
CY96_03105	COG1937	Protein conserved in bacteria
CY96_03110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_03110	COG0425	Belongs to the sulfur carrier protein TusA family
CY96_03115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_03115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_03120	COG0425	Belongs to the sulfur carrier protein TusA family
CY96_03125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_03125	COG0425	Belongs to the sulfur carrier protein TusA family
CY96_03135	COG2210	Belongs to the sulfur carrier protein TusA family
CY96_03140	COG0730	response to heat
CY96_03150	COG1316	TRANSCRIPTIONal
CY96_03155	COG0604	alcohol dehydrogenase
CY96_03160	COG1283	sodium-dependent phosphate transmembrane transporter activity
CY96_03175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_03175	COG3711	transcriptional antiterminator
CY96_03180	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY96_03185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY96_03205	COG3584	3D domain protein
CY96_03205	COG1388	LysM domain
CY96_03210	COG0577	efflux transmembrane transporter activity
CY96_03215	COG1136	(ABC) transporter
CY96_03225	COG5522	Integral membrane protein (intg_mem_TP0381)
CY96_03240	COG1114	Component of the transport system for branched-chain amino acids
CY96_03245	COG3546	catalase activity
CY96_03280	COG0586	Pfam SNARE associated Golgi protein
CY96_03315	COG0531	amino acid
CY96_03320	COG0475	glutathione-regulated potassium exporter activity
CY96_03330	COG1737	Transcriptional regulator
CY96_03340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_03340	COG1263	PTS System
CY96_03350	COG2259	Doxx family
CY96_03370	COG1522	sequence-specific DNA binding
CY96_03375	COG0165	Argininosuccinate lyase
CY96_03375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CY96_03380	COG0300	oxidoreductase activity
CY96_03390	COG2076	Multidrug Resistance protein
CY96_03400	COG1309	transcriptional regulator
CY96_03405	COG2814	Major facilitator Superfamily
CY96_03435	COG1136	(ABC) transporter
CY96_03440	COG0577	efflux transmembrane transporter activity
CY96_03445	COG1136	(ABC) transporter
CY96_03450	COG0577	efflux transmembrane transporter activity
CY96_03465	COG1733	regulation of RNA biosynthetic process
CY96_03480	COG4533	DNA binding
CY96_03485	COG2211	Major facilitator Superfamily
CY96_03500	COG0693	protein deglycase activity
CY96_03515	COG0531	amino acid
CY96_03530	COG1012	belongs to the aldehyde dehydrogenase family
CY96_03540	COG1132	(ABC) transporter
CY96_03545	COG1132	(ABC) transporter
CY96_03550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY96_03555	COG0765	amino acid transport
CY96_03560	COG1126	abc transporter atp-binding protein
CY96_03575	COG0189	ligase activity
CY96_03605	COG0028	Belongs to the TPP enzyme family
CY96_03610	COG3527	Alpha-acetolactate decarboxylase
CY96_03620	COG0561	phosphatase activity
CY96_03630	COG5632	N-Acetylmuramoyl-L-alanine amidase
CY96_03630	COG3409	Peptidoglycan-binding domain 1 protein
CY96_03635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY96_03660	COG0659	secondary active sulfate transmembrane transporter activity
CY96_03665	COG2244	polysaccharide biosynthetic process
CY96_03685	COG1024	Enoyl-CoA hydratase
CY96_03705	COG1363	Peptidase, m42
CY96_03745	COG0601	transmembrane transport
CY96_03750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY96_03755	COG0444	Belongs to the ABC transporter superfamily
CY96_03760	COG4608	Belongs to the ABC transporter superfamily
CY96_03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_03870	COG0477	Major facilitator Superfamily
CY96_03875	COG3290	protein histidine kinase activity
CY96_03880	COG4565	transcriptional regulatory protein
CY96_03885	COG3181	Tripartite tricarboxylate transporter family receptor
CY96_03915	COG4978	Transcriptional regulator
CY96_03915	COG0789	Transcriptional regulator
CY96_03930	COG0305	Participates in initiation and elongation during chromosome replication
CY96_03965	COG1288	antiporter activity
CY96_03980	COG0477	Major facilitator Superfamily
CY96_04005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_04095	COG1073	alpha beta
CY96_04160	COG1183	phosphatidylcholine synthase activity
CY96_04180	COG2376	Dihydroxyacetone kinase
CY96_04190	COG2376	Dihydroxyacetone kinase
CY96_04225	COG2373	Large extracellular alpha-helical protein
CY96_04290	COG1191	sigma factor activity
CY96_04300	COG2208	phosphoserine phosphatase activity
CY96_04305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CY96_04310	COG2205	protein histidine kinase activity
CY96_04310	COG5002	protein histidine kinase activity
CY96_04310	COG0784	Response regulator, receiver
CY96_04355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CY96_04380	COG0420	3'-5' exonuclease activity
CY96_04385	COG4717	serine-type aminopeptidase activity
CY96_04395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY96_04410	COG0346	lactoylglutathione lyase activity
CY96_04415	COG0346	lactoylglutathione lyase activity
CY96_04420	COG0457	Tetratricopeptide repeat
CY96_04430	COG2267	carboxylic ester hydrolase activity
CY96_04450	COG2140	Oxalate decarboxylase
CY96_04455	COG3620	sequence-specific DNA binding
CY96_04460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CY96_04465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CY96_04475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CY96_04480	COG1695	Transcriptional regulator
CY96_04500	COG3973	AAA domain
CY96_04525	COG4980	gas vesicle protein
CY96_04530	COG0537	adenosine 5'-monophosphoramidase activity
CY96_04535	COG1131	(ABC) transporter
CY96_04540	COG4473	ABC transporter
CY96_04555	COG1309	transcriptional regulator
CY96_04565	COG3402	PFAM membrane-flanked domain
CY96_04570	COG3428	Bacterial PH domain
CY96_04610	COG0697	spore germination
CY96_04615	COG3402	PFAM membrane-flanked domain
CY96_04620	COG3428	Bacterial PH domain
CY96_04625	COG2329	Antibiotic biosynthesis monooxygenase
CY96_04630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_04680	COG1309	transcriptional regulator
CY96_04685	COG1511	domain protein
CY96_04710	COG1609	Transcriptional regulator
CY96_04720	COG1234	tRNA 3'-trailer cleavage
CY96_04725	COG0095	Lipoate-protein ligase
CY96_04735	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_04745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CY96_04755	COG4208	sulfate ABC transporter
CY96_04770	COG1408	metallophosphoesterase
CY96_04775	COG1078	dGTPase activity
CY96_04785	COG1595	DNA-templated transcription, initiation
CY96_04790	COG3708	Transcriptional regulator
CY96_04790	COG2207	Transcriptional regulator
CY96_04800	COG2205	protein histidine kinase activity
CY96_04805	COG0745	RESPONSE REGULATOR receiver
CY96_04825	COG0501	Belongs to the peptidase M48B family
CY96_04830	COG0840	transmembrane signaling receptor activity
CY96_04835	COG3693	PFAM glycoside hydrolase, family 10
CY96_04850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CY96_04855	COG2224	Isocitrate lyase
CY96_04870	COG1278	Cold shock
CY96_04895	COG0398	Pfam SNARE associated Golgi protein
CY96_04955	COG0179	Fumarylacetoacetate (FAA) hydrolase
CY96_04980	COG0367	asparagine synthase
CY96_04990	COG0753	catalase activity
CY96_04995	COG0004	ammonium transporteR
CY96_05010	COG2996	Protein conserved in bacteria
CY96_05025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_05040	COG0561	phosphatase activity
CY96_05060	COG2267	carboxylic ester hydrolase activity
CY96_05075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CY96_05080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CY96_05085	COG5504	Zn-dependent protease
CY96_05110	COG0180	Tryptophanyl-tRNA synthetase
CY96_05120	COG4166	transmembrane transport
CY96_05125	COG0601	transmembrane transport
CY96_05130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CY96_05135	COG0444	Belongs to the ABC transporter superfamily
CY96_05140	COG4608	Belongs to the ABC transporter superfamily
CY96_05145	COG0534	Mate efflux family protein
CY96_05150	COG4166	transmembrane transport
CY96_05160	COG1393	Belongs to the ArsC family
CY96_05165	COG0861	Integral membrane protein TerC family
CY96_05175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY96_05185	COG1164	Oligoendopeptidase f
CY96_05200	COG2346	COG2346, Truncated hemoglobins
CY96_05205	COG4116	CYTH
CY96_05215	COG2357	RelA SpoT domain protein
CY96_05225	COG0564	pseudouridine synthase activity
CY96_05240	COG0772	Belongs to the SEDS family
CY96_05245	COG1216	Glycosyl transferase, family 2
CY96_05265	COG0457	Tetratricopeptide repeat
CY96_05265	COG0463	Glycosyl transferase, family 2
CY96_05285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CY96_05300	COG1091	dTDP-4-dehydrorhamnose reductase activity
CY96_05345	COG2153	protein acetylation
CY96_05355	COG2382	esterase
CY96_05375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY96_05390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CY96_05390	COG0512	Glutamine amidotransferase of anthranilate synthase
CY96_05425	COG1620	l-lactate permease
CY96_05430	COG5634	Uncharacterized conserved protein (DUF2278)
CY96_05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY96_05495	COG1476	TRANSCRIPTIONal
CY96_05525	COG4152	abc transporter atp-binding protein
CY96_05530	COG1668	transmembrane transport
CY96_05555	COG1686	Belongs to the peptidase S11 family
CY96_05560	COG0681	Belongs to the peptidase S26 family
CY96_05595	COG1012	belongs to the aldehyde dehydrogenase family
CY96_05605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CY96_05610	COG1177	transmembrane transport
CY96_05615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CY96_05625	COG2409	Drug exporters of the RND superfamily
CY96_05635	COG0564	pseudouridine synthase activity
CY96_05645	COG2340	Cysteine-rich secretory protein family
CY96_05650	COG0247	lactate metabolic process
CY96_05655	COG0277	FAD linked oxidase domain protein
CY96_05660	COG3835	regulator
CY96_05670	COG0745	RESPONSE REGULATOR receiver
CY96_05675	COG5002	protein histidine kinase activity
CY96_05680	COG2186	Transcriptional regulator
CY96_05700	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CY96_05710	COG2116	formate transmembrane transporter activity
CY96_05715	COG0861	Integral membrane protein TerC family
CY96_05720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CY96_05730	COG2030	dehydratase
CY96_05750	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_05755	COG3243	poly(R)-hydroxyalkanoic acid synthase
CY96_05765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CY96_05780	COG1840	ABC-type Fe3 transport system, periplasmic component
CY96_05785	COG3842	ATPase activity
CY96_05810	COG1349	DNA-binding transcription factor activity
CY96_05825	COG0235	Class ii aldolase
CY96_05835	COG2861	carbohydrate metabolic process
CY96_05845	COG3852	Histidine kinase
CY96_05850	COG1846	Transcriptional regulator
CY96_05860	COG2318	DinB family
CY96_05875	COG5002	protein histidine kinase activity
CY96_05885	COG0720	synthase
CY96_05900	COG4873	Protein conserved in bacteria
CY96_05930	COG1780	Probably involved in ribonucleotide reductase function
CY96_05935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CY96_05940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CY96_05945	COG1725	Transcriptional regulator
CY96_05950	COG1131	(ABC) transporter
CY96_05960	COG1131	(ABC) transporter
CY96_05980	COG1522	sequence-specific DNA binding
CY96_05990	COG1335	isochorismatase
CY96_06000	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY96_06005	COG2070	2-Nitropropane dioxygenase
CY96_06010	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CY96_06020	COG1696	Membrane protein involved in D-alanine export
CY96_06045	COG0716	FMN binding
CY96_06105	COG1846	Transcriptional regulator
CY96_06115	COG1301	dicarboxylic acid transport
CY96_06120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CY96_06125	COG4709	membrane
CY96_06130	COG3874	Sporulation protein YtfJ
CY96_06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY96_06155	COG0028	Belongs to the TPP enzyme family
CY96_06160	COG0440	acetolactate synthase activity
CY96_06235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CY96_06250	COG1183	phosphatidylcholine synthase activity
CY96_06255	COG1368	sulfuric ester hydrolase activity
CY96_06265	COG0019	diaminopimelate decarboxylase activity
CY96_06285	COG0529	Catalyzes the synthesis of activated sulfate
CY96_06290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY96_06310	COG1648	precorrin-2 dehydrogenase activity
CY96_06315	COG0733	neurotransmitter:sodium symporter activity
CY96_06340	COG1757	Na H antiporter
CY96_06355	COG4758	membrane
CY96_06360	COG4585	Histidine kinase
CY96_06365	COG2197	response regulator
CY96_06375	COG1114	Component of the transport system for branched-chain amino acids
CY96_06425	COG0730	response to heat
CY96_06430	COG0306	phosphate transporter
CY96_06435	COG1392	Phosphate transport regulator
CY96_06440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_06455	COG3852	Histidine kinase
CY96_06460	COG1801	Protein of unknown function DUF72
CY96_06475	COG0582	viral genome integration into host DNA
CY96_06480	COG5002	protein histidine kinase activity
CY96_06495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CY96_06495	COG0392	lysyltransferase activity
CY96_06510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY96_06515	COG1686	Belongs to the peptidase S11 family
CY96_06520	COG2715	membrane protein required for spore maturation
CY96_06525	COG0700	Nucleoside recognition
CY96_06530	COG1187	pseudouridine synthase activity
CY96_06540	COG1333	cytochrome c biogenesis protein
CY96_06545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY96_06550	COG0745	RESPONSE REGULATOR receiver
CY96_06555	COG5002	protein histidine kinase activity
CY96_06560	COG2096	Adenosyltransferase
CY96_06575	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CY96_06580	COG1141	Ferredoxin
CY96_06590	COG0514	ATP-dependent DNA helicase (RecQ)
CY96_06595	COG1266	CAAX protease self-immunity
CY96_06605	COG1408	metallophosphoesterase
CY96_06610	COG0789	Transcriptional regulator
CY96_06620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY96_06640	COG0492	ferredoxin-NADP+ reductase activity
CY96_06645	COG0252	asparaginase activity
CY96_06715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CY96_06730	COG0142	geranyltranstransferase activity
CY96_06740	COG0142	geranyltranstransferase activity
CY96_06765	COG0457	Tetratricopeptide repeat
CY96_06785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CY96_06790	COG2010	Cytochrome c
CY96_06790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CY96_06795	COG4347	Protein of unknown function (DUF1405)
CY96_06810	COG2738	Putative neutral zinc metallopeptidase
CY96_06820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_06825	COG1694	Mazg nucleotide pyrophosphohydrolase
CY96_06845	COG0438	transferase activity, transferring glycosyl groups
CY96_06880	COG1199	ATP-dependent helicase activity
CY96_06880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CY96_06900	COG3935	DnaD domain protein
CY96_06905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CY96_06915	COG4499	WXG100 protein secretion system (Wss), protein YukC
CY96_06915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_06970	COG0116	Belongs to the methyltransferase superfamily
CY96_06980	COG1199	ATP-dependent helicase activity
CY96_06985	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CY96_06995	COG0024	Methionine aminopeptidase
CY96_07005	COG2233	PERMEase
CY96_07010	COG2311	Membrane
CY96_07020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CY96_07030	COG0456	acetyltransferase
CY96_07070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CY96_07085	COG3944	biosynthesis protein
CY96_07095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY96_07110	COG1215	transferase activity, transferring glycosyl groups
CY96_07115	COG0438	transferase activity, transferring glycosyl groups
CY96_07130	COG0454	-acetyltransferase
CY96_07150	COG0328	RNA-DNA hybrid ribonuclease activity
CY96_07185	COG3403	YqcI/YcgG family
CY96_07190	COG1280	lysine exporter protein (LysE YggA)
CY96_07210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CY96_07215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY96_07225	COG0475	glutathione-regulated potassium exporter activity
CY96_07230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CY96_07235	COG4978	Transcriptional regulator
CY96_07235	COG0789	Transcriptional regulator
CY96_07245	COG2323	membrane
CY96_07250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CY96_07285	COG1923	regulation of RNA biosynthetic process
CY96_07295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CY96_07300	COG1360	Flagellar Motor Protein
CY96_07305	COG2201	protein-glutamate methylesterase activity
CY96_07310	COG0643	Histidine kinase
CY96_07310	COG2198	Histidine kinase
CY96_07315	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CY96_07315	COG1776	CheC inhibitor of MCP methylation
CY96_07330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CY96_07350	COG1256	bacterial-type flagellum assembly
CY96_07355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CY96_07375	COG1815	bacterial-type flagellum-dependent cell motility
CY96_07380	COG1558	bacterial-type flagellum-dependent cell motility
CY96_07385	COG1677	Flagellar hook-basal body complex protein FliE
CY96_07390	COG1766	The M ring may be actively involved in energy transduction
CY96_07395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CY96_07405	COG1157	protein secretion by the type III secretion system
CY96_07425	COG1749	Flagellar hook protein flgE
CY96_07440	COG0835	chemotaxis
CY96_07440	COG0784	Response regulator, receiver
CY96_07450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CY96_07455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CY96_07460	COG0741	lytic transglycosylase activity
CY96_07470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CY96_07475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CY96_07475	COG1776	CheC inhibitor of MCP methylation
CY96_07485	COG1338	Plays a role in the flagellum-specific transport system
CY96_07490	COG1987	bacterial-type flagellum assembly
CY96_07500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CY96_07505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CY96_07510	COG1419	protein localization to endoplasmic reticulum
CY96_07515	COG4786	Flagellar basal body rod
CY96_07520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY96_07550	COG2329	Antibiotic biosynthesis monooxygenase
CY96_07590	COG1177	transmembrane transport
CY96_07620	COG0406	alpha-ribazole phosphatase activity
CY96_07650	COG0367	asparagine synthase
CY96_07680	COG1802	Transcriptional regulator
CY96_07685	COG0697	spore germination
CY96_07695	COG0523	cobalamin synthesis protein
CY96_07700	COG0701	Predicted permease
CY96_07715	COG1757	Na H antiporter
CY96_07720	COG0789	Transcriptional regulator
CY96_07750	COG0534	Mate efflux family protein
CY96_07755	COG3340	Belongs to the peptidase S51 family
CY96_07775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY96_07965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY96_08035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CY96_08035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CY96_08060	COG1484	DNA-dependent DNA replication
CY96_08085	COG2801	Transposase and inactivated derivatives
CY96_08110	COG2733	membrane
CY96_08145	COG1131	(ABC) transporter
CY96_08165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY96_08170	COG0528	UMP kinase activity
CY96_08180	COG1027	Aspartate ammonia-lyase
CY96_08185	COG0281	malic enzyme
CY96_08190	COG4191	Histidine kinase
CY96_08195	COG0784	Response regulator, receiver
CY96_08205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY96_08255	COG2814	Major facilitator Superfamily
CY96_08270	COG1695	Transcriptional regulator
CY96_08280	COG0477	Major facilitator Superfamily
CY96_08290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY96_08295	COG2223	nitrite transmembrane transporter activity
CY96_08300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY96_08320	COG0733	neurotransmitter:sodium symporter activity
CY96_08335	COG5566	PFAM Mor transcription activator
CY96_08340	COG2323	membrane
CY96_08365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CY96_08375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY96_08380	COG0028	Belongs to the TPP enzyme family
CY96_08400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CY96_08420	COG2814	Major facilitator Superfamily
CY96_08425	COG3384	dioxygenase
CY96_08435	COG3279	Response regulator of the LytR AlgR family
CY96_08440	COG0427	acetyl-CoA hydrolase
CY96_08460	COG4166	transmembrane transport
CY96_08465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_08470	COG0745	RESPONSE REGULATOR receiver
CY96_08485	COG1914	H( )-stimulated, divalent metal cation uptake system
CY96_08500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CY96_08510	COG0531	amino acid
CY96_08545	COG1309	transcriptional regulator
CY96_08550	COG2390	Transcriptional regulator
CY96_08560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_08565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CY96_08580	COG4846	Membrane protein involved in cytochrome C biogenesis
CY96_08605	COG0006	proline dipeptidase activity
CY96_08615	COG2132	Multicopper oxidase
CY96_08645	COG1114	Component of the transport system for branched-chain amino acids
CY96_08655	COG1276	copper resistance
CY96_08655	COG2372	response to copper ion
CY96_08660	COG4549	nuclear export factor GLE1
CY96_08665	COG0697	spore germination
CY96_08670	COG0583	DNA-binding transcription factor activity
CY96_08675	COG1959	2 iron, 2 sulfur cluster binding
CY96_08680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CY96_08685	COG0778	Nitroreductase
CY96_08700	COG0628	permease
CY96_08710	COG1231	oxidoreductase activity
CY96_08715	COG0523	cobalamin synthesis protein
CY96_08725	COG0411	ABC transporter
CY96_08745	COG0583	DNA-binding transcription factor activity
CY96_08780	COG1271	oxidase subunit
CY96_08785	COG1294	oxidase, subunit
CY96_08790	COG4988	ABC transporter
CY96_08795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CY96_08805	COG1216	Glycosyl transferase, family 2
CY96_08845	COG1686	Belongs to the peptidase S11 family
CY96_08865	COG1388	LysM domain
CY96_08865	COG0791	NLP P60 protein
CY96_08875	COG1132	(ABC) transporter
CY96_08880	COG0745	RESPONSE REGULATOR receiver
CY96_08885	COG5002	protein histidine kinase activity
CY96_08890	COG0300	oxidoreductase activity
CY96_08900	COG0726	polysaccharide deacetylase
CY96_08920	COG0460	homoserine dehydrogenase
CY96_08945	COG1316	TRANSCRIPTIONal
CY96_08955	COG0745	RESPONSE REGULATOR receiver
CY96_08960	COG5002	protein histidine kinase activity
CY96_08965	COG0726	polysaccharide deacetylase
CY96_08975	COG1285	pathogenesis
CY96_08980	COG1247	-acetyltransferase
CY96_08990	COG4264	IucA IucC family
CY96_08995	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_09010	COG1082	Xylose isomerase domain protein TIM barrel
CY96_09020	COG2814	Major facilitator Superfamily
CY96_09025	COG1279	arginine transmembrane transporter activity
CY96_09030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_09040	COG1752	Esterase of the alpha-beta hydrolase superfamily
CY96_09075	COG0577	efflux transmembrane transporter activity
CY96_09080	COG2002	toxin-antitoxin pair type II binding
CY96_09085	COG1404	Belongs to the peptidase S8 family
CY96_09120	COG0840	transmembrane signaling receptor activity
CY96_09135	COG3949	Membrane
CY96_09140	COG0783	Belongs to the Dps family
CY96_09155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY96_09165	COG1231	oxidoreductase activity
CY96_09170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_09175	COG4989	oxidoreductase activity
CY96_09180	COG0523	cobalamin synthesis protein
CY96_09185	COG0456	acetyltransferase
CY96_09190	COG0803	Belongs to the bacterial solute-binding protein 9 family
CY96_09200	COG0702	epimerase
CY96_09210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY96_09220	COG4166	transmembrane transport
CY96_09245	COG5337	Spore coat protein CotH
CY96_09250	COG1051	belongs to the nudix hydrolase family
CY96_09255	COG0586	Pfam SNARE associated Golgi protein
CY96_09260	COG2244	polysaccharide biosynthetic process
CY96_09270	COG0701	Predicted permease
CY96_09275	COG3689	TIGRFAM TIGR03943 family protein
CY96_09280	COG1607	acyl-coa hydrolase
CY96_09290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY96_09305	COG0702	epimerase
CY96_09310	COG2839	Protein conserved in bacteria
CY96_09315	COG1253	flavin adenine dinucleotide binding
CY96_09330	COG1114	Component of the transport system for branched-chain amino acids
CY96_09335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY96_09350	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY96_09360	COG1876	peptidase activity
CY96_09370	COG0154	amidase activity
CY96_09375	COG2211	Major facilitator Superfamily
CY96_09390	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY96_09400	COG0561	phosphatase activity
CY96_09415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CY96_09425	COG1819	glycosyl
CY96_09430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_09435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_09465	COG0456	acetyltransferase
CY96_09485	COG0842	Transport permease protein
CY96_09485	COG1511	domain protein
CY96_09500	COG4499	WXG100 protein secretion system (Wss), protein YukC
CY96_09605	COG3874	Sporulation protein YtfJ
CY96_09630	COG2226	methyltransferase
CY96_09650	COG1082	Xylose isomerase domain protein TIM barrel
CY96_09655	COG0346	lactoylglutathione lyase activity
CY96_09665	COG0604	alcohol dehydrogenase
CY96_09670	COG1595	DNA-templated transcription, initiation
CY96_09695	COG0386	Belongs to the glutathione peroxidase family
CY96_09700	COG1305	Transglutaminase-like
CY96_09705	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CY96_09710	COG0714	Associated with various cellular activities
CY96_09725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CY96_09730	COG1140	nitrate reductase beta subunit
CY96_09735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CY96_09740	COG2181	nitrate reductase activity
CY96_09745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY96_09750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CY96_09755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY96_09760	COG0303	'Molybdopterin
CY96_09765	COG0314	molybdopterin synthase activity
CY96_09770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CY96_09775	COG2223	nitrite transmembrane transporter activity
CY96_09790	COG1648	precorrin-2 dehydrogenase activity
CY96_09800	COG1587	Uroporphyrinogen-III synthase
CY96_09800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CY96_09805	COG2146	nitrite reductase [NAD(P)H] activity
CY96_09810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CY96_09815	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CY96_09850	COG2359	stage V sporulation protein S
CY96_09870	COG0457	Tetratricopeptide repeat
CY96_09885	COG1418	mRNA catabolic process
CY96_09890	COG0488	(ABC) transporter
CY96_09905	COG0629	single-stranded DNA binding
CY96_09920	COG1413	lyase activity
CY96_09935	COG2136	Putative SAM-dependent methyltransferase
CY96_09935	COG2521	methyltransferase
CY96_09940	COG0018	arginyl-trna synthetase
CY96_09975	COG0017	Asparaginyl-tRNA synthetase
CY96_09980	COG0733	neurotransmitter:sodium symporter activity
CY96_10005	COG2610	gluconate transmembrane transporter activity
CY96_10015	COG1794	racemase activity, acting on amino acids and derivatives
CY96_10025	COG0456	acetyltransferase
CY96_10035	COG3655	Transcriptional regulator
CY96_10040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CY96_10050	COG1131	(ABC) transporter
CY96_10055	COG4473	ABC transporter
CY96_10065	COG0546	phosphoglycolate phosphatase activity
CY96_10080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY96_10095	COG0768	penicillin binding
CY96_10105	COG0204	Acyl-transferase
CY96_10110	COG1272	protein, Hemolysin III
CY96_10120	COG0805	protein transport
CY96_10130	COG1307	EDD domain protein, DegV family
CY96_10140	COG1999	signal sequence binding
CY96_10150	COG0367	asparagine synthase
CY96_10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY96_10170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_10175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY96_10195	COG1335	isochorismatase
CY96_10205	COG0668	transmembrane transport
CY96_10210	COG2203	Gaf domain
CY96_10210	COG4585	Histidine kinase
CY96_10215	COG2197	response regulator
CY96_10220	COG1737	Transcriptional regulator
CY96_10225	COG0384	phenazine biosynthesis protein PhzF
CY96_10230	COG1064	alcohol dehydrogenase
CY96_10245	COG1070	Carbohydrate kinase
CY96_10255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CY96_10285	COG1125	glycine betaine transport
CY96_10285	COG0517	IMP dehydrogenase activity
CY96_10290	COG1174	glycine betaine transport
CY96_10325	COG1253	flavin adenine dinucleotide binding
CY96_10330	COG1012	belongs to the aldehyde dehydrogenase family
CY96_10335	COG5506	Protein of unknown function (DUF1694)
CY96_10350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY96_10355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CY96_10360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CY96_10365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CY96_10370	COG0456	acetyltransferase
CY96_10375	COG3829	transcription factor binding
CY96_10380	COG1509	lysine 2,3-aminomutase activity
CY96_10415	COG4991	sh3 domain protein
CY96_10415	COG3064	Membrane
CY96_10415	COG0515	serine threonine protein kinase
CY96_10425	COG0671	phosphoesterase, PA-phosphatase related
CY96_10430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CY96_10440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY96_10515	COG0300	oxidoreductase activity
CY96_10535	COG4499	WXG100 protein secretion system (Wss), protein YukC
CY96_10535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_10545	COG2814	Major facilitator Superfamily
CY96_10550	COG4841	protein insertion into membrane
CY96_10555	COG0372	Belongs to the citrate synthase family
CY96_10560	COG2079	MmgE PrpD family protein
CY96_10565	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CY96_10570	COG1960	acyl-CoA dehydrogenase activity
CY96_10575	COG2084	Dehydrogenase
CY96_10585	COG1280	lysine exporter protein (LysE YggA)
CY96_10590	COG1024	Enoyl-CoA hydratase
CY96_10605	COG0420	3'-5' exonuclease activity
CY96_10610	COG0419	ATPase involved in DNA repair
CY96_10630	COG2223	nitrite transmembrane transporter activity
CY96_10635	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_10640	COG1169	isochorismate synthase
CY96_10645	COG1021	2,3-dihydroxybenzoate-AMP ligase
CY96_10650	COG1535	isochorismatase
CY96_10650	COG3433	isochorismatase activity
CY96_10655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY96_10660	COG3251	PFAM MbtH domain protein
CY96_10665	COG2814	Major facilitator Superfamily
CY96_10680	COG0776	regulation of translation
CY96_10690	COG2318	DinB family
CY96_10700	COG1115	amino acid carrier protein
CY96_10715	COG2329	Antibiotic biosynthesis monooxygenase
CY96_10720	COG1187	pseudouridine synthase activity
CY96_10725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CY96_10730	COG1136	(ABC) transporter
CY96_10740	COG0028	Belongs to the TPP enzyme family
CY96_10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY96_10790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_10825	COG1247	-acetyltransferase
CY96_10860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_10890	COG0583	DNA-binding transcription factor activity
CY96_10895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY96_10915	COG0583	DNA-binding transcription factor activity
CY96_10920	COG2258	MOSC domain
CY96_10935	COG1132	(ABC) transporter
CY96_10940	COG1132	(ABC) transporter
CY96_11000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY96_11005	COG1595	DNA-templated transcription, initiation
CY96_11030	COG1649	PFAM Uncharacterised BCR, COG1649
CY96_11055	COG2971	BadF BadG BcrA BcrD
CY96_11075	COG1846	Transcriptional regulator
CY96_11090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_11120	COG1309	transcriptional regulator
CY96_11150	COG3615	Tellurite resistance protein tehB
CY96_11150	COG0500	methyltransferase
CY96_11160	COG2226	methyltransferase
CY96_11165	COG3961	Belongs to the TPP enzyme family
CY96_11170	COG1846	Transcriptional regulator
CY96_11200	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY96_11225	COG2002	toxin-antitoxin pair type II binding
CY96_11235	COG0730	response to heat
CY96_11240	COG0110	maltose O-acetyltransferase activity
CY96_11245	COG1686	Belongs to the peptidase S11 family
CY96_11255	COG2814	Major facilitator Superfamily
CY96_11295	COG2312	Erythromycin esterase
CY96_11300	COG0741	lytic transglycosylase activity
CY96_11305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_11350	COG1760	l-serine dehydratase
CY96_11355	COG1760	l-serine dehydratase
CY96_11360	COG0814	amino acid
CY96_11380	COG1533	DNA photolyase activity
CY96_11400	COG0772	Belongs to the SEDS family
CY96_11405	COG2239	Acts as a magnesium transporter
CY96_11415	COG0768	penicillin binding
CY96_11420	COG1595	DNA-templated transcription, initiation
CY96_11430	COG0768	penicillin binding
CY96_11445	COG1408	metallophosphoesterase
CY96_11455	COG1131	(ABC) transporter
CY96_11465	COG1309	transcriptional regulator
CY96_11480	COG1960	acyl-CoA dehydrogenase activity
CY96_11485	COG0439	Biotin carboxylase
CY96_11490	COG0511	ligase activity, forming carbon-carbon bonds
CY96_11495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CY96_11500	COG1024	Enoyl-CoA hydratase
CY96_11505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CY96_11510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY96_11530	COG0572	uridine kinase
CY96_11540	COG2318	DinB family
CY96_11550	COG1686	Belongs to the peptidase S11 family
CY96_11570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CY96_11585	COG3227	Zinc metalloprotease (Elastase)
CY96_11590	COG2207	Transcriptional regulator
CY96_11620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CY96_11645	COG2814	Major facilitator Superfamily
CY96_11650	COG2226	methyltransferase
CY96_11690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_11695	COG2368	4-hydroxyphenylacetate
CY96_11705	COG1063	alcohol dehydrogenase
CY96_11715	COG2323	membrane
CY96_11720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CY96_11730	COG3386	PFAM SMP-30 Gluconolaconase
CY96_11745	COG3773	Cell wall hydrolase
CY96_11755	COG0745	RESPONSE REGULATOR receiver
CY96_11760	COG2205	protein histidine kinase activity
CY96_11775	COG1136	(ABC) transporter
CY96_11780	COG0577	efflux transmembrane transporter activity
CY96_11800	COG0460	homoserine dehydrogenase
CY96_11805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_11815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CY96_11885	COG2124	cytochrome p450
CY96_11920	COG0561	phosphatase activity
CY96_11925	COG5002	protein histidine kinase activity
CY96_11940	COG1819	glycosyl
CY96_11945	COG1794	racemase activity, acting on amino acids and derivatives
CY96_11970	COG2205	protein histidine kinase activity
CY96_11975	COG0582	viral genome integration into host DNA
CY96_12040	COG0745	RESPONSE REGULATOR receiver
CY96_12045	COG5002	protein histidine kinase activity
CY96_12050	COG0604	alcohol dehydrogenase
CY96_12055	COG0671	phosphoesterase, PA-phosphatase related
CY96_12100	COG2814	Major facilitator Superfamily
CY96_12105	COG2814	Major facilitator Superfamily
CY96_12125	COG0584	glycerophosphoryl diester phosphodiesterase
CY96_12145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_12150	COG0697	spore germination
CY96_12195	COG2223	nitrite transmembrane transporter activity
CY96_12210	COG0592	DNA-directed DNA polymerase activity
CY96_12240	COG3878	Protein conserved in bacteria
CY96_12300	COG0322	excinuclease ABC activity
CY96_12340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY96_12370	COG0745	RESPONSE REGULATOR receiver
CY96_12375	COG5002	protein histidine kinase activity
CY96_12390	COG1136	(ABC) transporter
CY96_12395	COG0577	efflux transmembrane transporter activity
CY96_12400	COG1073	alpha beta
CY96_12410	COG0076	glutamate decarboxylase activity
CY96_12425	COG1523	belongs to the glycosyl hydrolase 13 family
CY96_12430	COG3227	Zinc metalloprotease (Elastase)
CY96_12435	COG0737	Belongs to the 5'-nucleotidase family
CY96_12450	COG0201	protein transport
CY96_12455	COG0697	spore germination
CY96_12460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_12500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_12515	COG2959	enzyme of heme biosynthesis
CY96_12520	COG3409	Peptidoglycan-binding domain 1 protein
CY96_12520	COG3773	Cell wall hydrolase
CY96_12555	COG1309	transcriptional regulator
CY96_12585	COG3284	Transcriptional regulator
CY96_12600	COG1349	DNA-binding transcription factor activity
CY96_12615	COG1959	2 iron, 2 sulfur cluster binding
CY96_12630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY96_12635	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY96_12640	COG0022	dehydrogenase e1 component
CY96_12645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY96_12660	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_12665	COG0456	acetyltransferase
CY96_12665	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY96_12670	COG2816	NAD+ diphosphatase activity
CY96_12695	COG4176	ABC-type proline glycine betaine transport system permease component
CY96_12700	COG4175	Glycine betaine
CY96_12700	COG0517	IMP dehydrogenase activity
CY96_12710	COG0740	serine-type endopeptidase activity
CY96_12730	COG2153	protein acetylation
CY96_12735	COG3397	chitin binding
CY96_12740	COG1819	glycosyl
CY96_12760	COG2205	protein histidine kinase activity
CY96_12765	COG2226	methyltransferase
CY96_12770	COG2315	Protein conserved in bacteria
CY96_12825	COG0456	acetyltransferase
CY96_12830	COG3973	AAA domain
CY96_12845	COG0514	ATP-dependent DNA helicase (RecQ)
CY96_12880	COG4637	Psort location Cytoplasmic, score
CY96_12895	COG3397	chitin binding
CY96_12910	COG1162	GTPase activity
CY96_12915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CY96_12925	COG1012	belongs to the aldehyde dehydrogenase family
CY96_12930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CY96_12940	COG3938	Belongs to the proline racemase family
CY96_12945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CY96_12995	COG1078	dGTPase activity
CY96_13000	COG0586	Pfam SNARE associated Golgi protein
CY96_13010	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CY96_13020	COG4166	transmembrane transport
CY96_13030	COG4948	Mandelate Racemase Muconate Lactonizing
CY96_13045	COG0667	Aldo Keto reductase
CY96_13095	COG3850	Histidine kinase
CY96_13095	COG5002	protein histidine kinase activity
CY96_13100	COG0745	RESPONSE REGULATOR receiver
CY96_13135	COG1164	Oligoendopeptidase f
CY96_13140	COG1307	EDD domain protein, DegV family
CY96_13190	COG2814	Major facilitator Superfamily
CY96_13200	COG1664	Polymer-forming cytoskeletal
CY96_13205	COG0789	Transcriptional regulator
CY96_13210	COG4533	DNA binding
CY96_13215	COG2814	Major facilitator Superfamily
CY96_13215	COG0477	Major facilitator Superfamily
CY96_13235	COG2261	transglycosylase associated protein
CY96_13250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CY96_13295	COG0436	Aminotransferase
CY96_13300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CY96_13310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CY96_13325	COG1131	(ABC) transporter
CY96_13375	COG0628	permease
CY96_13390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY96_13395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY96_13400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY96_13435	COG2746	aminoglycoside 3-N-acetyltransferase activity
CY96_13455	COG0697	spore germination
CY96_13475	COG4912	Dna alkylation repair
CY96_13485	COG0346	lactoylglutathione lyase activity
CY96_13495	COG0726	polysaccharide deacetylase
CY96_13500	COG0861	Integral membrane protein TerC family
CY96_13505	COG1368	sulfuric ester hydrolase activity
CY96_13515	COG0488	(ABC) transporter
CY96_13525	COG1033	growth of symbiont in host cell
CY96_13525	COG2409	Drug exporters of the RND superfamily
CY96_13530	COG1309	transcriptional regulator
CY96_13550	COG0287	Prephenate dehydrogenase
CY96_13565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CY96_13565	COG1605	Chorismate mutase
CY96_13605	COG1388	LysM domain
CY96_13605	COG3584	3D domain protein
CY96_13615	COG0346	lactoylglutathione lyase activity
CY96_13645	COG1879	ABC-type sugar transport system periplasmic component
CY96_13650	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY96_13655	COG1172	Belongs to the binding-protein-dependent transport system permease family
CY96_13665	COG2390	Transcriptional regulator
CY96_13670	COG1070	Carbohydrate kinase
CY96_13690	COG2329	Antibiotic biosynthesis monooxygenase
CY96_13710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_13725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY96_13730	COG4187	Peptidase family M20/M25/M40
CY96_13735	COG1414	Transcriptional regulator
CY96_13740	COG0833	amino acid
CY96_13750	COG3239	Fatty acid desaturase
CY96_13760	COG2720	vancomycin resistance protein
CY96_13765	COG1785	Belongs to the alkaline phosphatase family
CY96_13775	COG3655	Transcriptional regulator
CY96_13800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_13805	COG0346	lactoylglutathione lyase activity
CY96_13830	COG0714	Associated with various cellular activities
CY96_13855	COG0463	Glycosyl transferase, family 2
CY96_13885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY96_13890	COG0753	catalase activity
CY96_13930	COG0714	Associated with various cellular activities
CY96_13970	COG0778	Nitroreductase
CY96_13975	COG1846	Transcriptional regulator
CY96_13990	COG1051	belongs to the nudix hydrolase family
CY96_13995	COG3831	ATPase activity
CY96_13995	COG4884	unkown
CY96_14010	COG1136	(ABC) transporter
CY96_14010	COG0577	efflux transmembrane transporter activity
CY96_14040	COG0590	tRNA wobble adenosine to inosine editing
CY96_14040	COG0037	tRNA processing
CY96_14045	COG0456	acetyltransferase
CY96_14060	COG0697	spore germination
CY96_14065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_14110	COG0730	response to heat
CY96_14120	COG0833	amino acid
CY96_14130	COG4335	DNA alkylation repair
CY96_14200	COG1984	allophanate hydrolase subunit 2
CY96_14205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CY96_14210	COG1414	Transcriptional regulator
CY96_14220	COG3142	Participates in the control of copper homeostasis
CY96_14230	COG0640	Transcriptional regulator
CY96_14240	COG1960	acyl-CoA dehydrogenase activity
CY96_14280	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CY96_14295	COG3848	Pyruvate phosphate dikinase
CY96_14295	COG0574	Belongs to the PEP-utilizing enzyme family
CY96_14305	COG0367	asparagine synthase
CY96_14310	COG0583	DNA-binding transcription factor activity
CY96_14340	COG1522	sequence-specific DNA binding
CY96_14345	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_14350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_14370	COG1063	alcohol dehydrogenase
CY96_14380	COG1027	Aspartate ammonia-lyase
CY96_14385	COG0252	asparaginase activity
CY96_14390	COG1396	sequence-specific DNA binding
CY96_14430	COG5002	protein histidine kinase activity
CY96_14435	COG0745	RESPONSE REGULATOR receiver
CY96_14445	COG5002	protein histidine kinase activity
CY96_14470	COG2207	Transcriptional regulator
CY96_14485	COG0322	excinuclease ABC activity
CY96_14490	COG0531	amino acid
CY96_14495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY96_14505	COG0531	amino acid
CY96_14510	COG0697	spore germination
CY96_14520	COG0784	Response regulator, receiver
CY96_14525	COG4191	Histidine kinase
CY96_14540	COG1115	amino acid carrier protein
CY96_14560	COG0737	Belongs to the 5'-nucleotidase family
CY96_14565	COG2267	carboxylic ester hydrolase activity
CY96_14570	COG1335	isochorismatase
CY96_14590	COG0583	DNA-binding transcription factor activity
CY96_14595	COG2814	Major facilitator Superfamily
CY96_14620	COG0598	Magnesium transport protein CorA
CY96_14640	COG1073	alpha beta
CY96_14660	COG0415	Belongs to the DNA photolyase family
CY96_14670	COG1846	Transcriptional regulator
CY96_14690	COG2814	Major facilitator Superfamily
CY96_14700	COG0657	acetylesterase activity
CY96_14705	COG0288	reversible hydration of carbon dioxide
CY96_14715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY96_14720	COG5609	conserved protein (DUF2294)
CY96_14725	COG2814	Major facilitator Superfamily
CY96_14745	COG0726	polysaccharide deacetylase
CY96_14755	COG1575	Belongs to the MenA family. Type 1 subfamily
CY96_14780	COG0798	PFAM Bile acid sodium symporter
CY96_14785	COG0346	lactoylglutathione lyase activity
CY96_14790	COG0640	Transcriptional regulator
CY96_14800	COG0561	phosphatase activity
CY96_14805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CY96_14805	COG3320	Male sterility
CY96_14830	COG0346	lactoylglutathione lyase activity
CY96_14920	COG2814	Major facilitator Superfamily
CY96_14940	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CY96_14950	COG1690	Belongs to the RtcB family
CY96_14960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CY96_14980	COG0577	efflux transmembrane transporter activity
CY96_14995	COG3850	Histidine kinase
CY96_14995	COG5002	protein histidine kinase activity
CY96_15005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_15035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CY96_15075	COG5632	N-Acetylmuramoyl-L-alanine amidase
CY96_15075	COG3409	Peptidoglycan-binding domain 1 protein
CY96_15345	COG5444	nuclease activity
CY96_15355	COG5444	nuclease activity
CY96_15490	COG1876	peptidase activity
CY96_15495	COG2843	Capsule synthesis protein
CY96_15505	COG0477	Major facilitator Superfamily
CY96_15520	COG1846	Transcriptional regulator
CY96_15525	COG2814	Major facilitator Superfamily
CY96_15535	COG2031	fatty acid transporter
CY96_15600	COG1288	antiporter activity
CY96_15605	COG2356	endonuclease I
CY96_15625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CY96_15645	COG1733	regulation of RNA biosynthetic process
CY96_15650	COG0778	Nitroreductase
CY96_15680	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_15690	COG1131	(ABC) transporter
CY96_15715	COG1011	Hydrolase
CY96_15740	COG0180	Tryptophanyl-tRNA synthetase
CY96_15750	COG0628	permease
CY96_15780	COG0500	methyltransferase
CY96_15790	COG0477	Major facilitator Superfamily
CY96_15820	COG1253	flavin adenine dinucleotide binding
CY96_15825	COG0789	Transcriptional regulator
CY96_15835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CY96_15865	COG0697	spore germination
CY96_15875	COG1357	PFAM Pentapeptide repeats (8 copies)
CY96_15880	COG3813	Protein conserved in bacteria
CY96_15885	COG2706	6-phosphogluconolactonase activity
CY96_15890	COG1070	Carbohydrate kinase
CY96_15900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CY96_15905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CY96_15910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CY96_15915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CY96_15935	COG0840	transmembrane signaling receptor activity
CY96_15950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY96_15950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY96_15955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CY96_15960	COG1733	regulation of RNA biosynthetic process
CY96_15985	COG2824	Alkylphosphonate utilization operon protein PhnA
CY96_15990	COG0659	secondary active sulfate transmembrane transporter activity
CY96_16005	COG0814	amino acid
CY96_16030	COG2188	Transcriptional regulator
CY96_16035	COG0673	inositol 2-dehydrogenase activity
CY96_16055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_16075	COG0384	phenazine biosynthesis protein PhzF
CY96_16085	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_16090	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY96_16095	COG1733	regulation of RNA biosynthetic process
CY96_16110	COG0726	polysaccharide deacetylase
CY96_16120	COG1191	sigma factor activity
CY96_16175	COG1151	hydroxylamine reductase activity
CY96_16205	COG2072	flavoprotein involved in K transport
CY96_16240	COG1113	amino acid transport
CY96_16245	COG2814	Major facilitator Superfamily
CY96_16280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CY96_16285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY96_16295	COG1247	-acetyltransferase
CY96_16300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_16305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_16310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_16315	COG3739	integral membrane protein
CY96_16345	COG0583	DNA-binding transcription factor activity
CY96_16390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CY96_16395	COG1164	Oligoendopeptidase f
CY96_16400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CY96_16425	COG0584	glycerophosphoryl diester phosphodiesterase
CY96_16440	COG0640	Transcriptional regulator
CY96_16445	COG0604	alcohol dehydrogenase
CY96_16455	COG0457	Tetratricopeptide repeat
CY96_16465	COG2808	Putative FMN-binding domain
CY96_16470	COG0456	acetyltransferase
CY96_16470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY96_16485	COG0277	FAD linked oxidase domain protein
CY96_16510	COG1183	phosphatidylcholine synthase activity
CY96_16525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_16525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_16530	COG1252	NADH dehydrogenase
CY96_16540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CY96_16550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY96_16560	COG0457	Tetratricopeptide repeat
CY96_16635	COG3852	Histidine kinase
CY96_16645	COG1285	pathogenesis
CY96_16655	COG2514	catechol 2,3-dioxygenase activity
CY96_16660	COG2720	vancomycin resistance protein
CY96_16690	COG1278	Cold shock
CY96_16700	COG0716	FMN binding
CY96_16730	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_16740	COG0165	Argininosuccinate lyase
CY96_16755	COG4145	pantothenate transmembrane transporter activity
CY96_16765	COG1012	belongs to the aldehyde dehydrogenase family
CY96_16770	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_16780	COG1657	PFAM Prenyltransferase squalene oxidase
CY96_16785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CY96_16790	COG2962	Rard protein
CY96_16795	COG3326	Membrane
CY96_16810	COG0489	protein tyrosine kinase activity
CY96_16820	COG0314	molybdopterin synthase activity
CY96_16825	COG0303	'Molybdopterin
CY96_16830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY96_16835	COG2116	formate transmembrane transporter activity
CY96_16845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CY96_16850	COG5609	conserved protein (DUF2294)
CY96_16855	COG2427	Protein of unknown function (DUF1641)
CY96_16860	COG3383	formate dehydrogenase (NAD+) activity
CY96_16865	COG0697	spore germination
CY96_16880	COG0531	amino acid
CY96_16915	COG2226	methyltransferase
CY96_16920	COG4166	transmembrane transport
CY96_16925	COG4166	transmembrane transport
CY96_16930	COG4166	transmembrane transport
CY96_16935	COG1316	TRANSCRIPTIONal
CY96_16945	COG1595	DNA-templated transcription, initiation
CY96_16955	COG1131	(ABC) transporter
CY96_16965	COG0673	inositol 2-dehydrogenase activity
CY96_16970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CY96_16975	COG0187	DNA topoisomerase II activity
CY96_16980	COG1832	CoA-binding protein
CY96_16985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY96_16990	COG0745	RESPONSE REGULATOR receiver
CY96_17010	COG4841	protein insertion into membrane
CY96_17015	COG0824	Thioesterase
CY96_17045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY96_17060	COG1132	(ABC) transporter
CY96_17065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CY96_17075	COG0726	polysaccharide deacetylase
CY96_17095	COG2211	Major facilitator Superfamily
CY96_17105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CY96_17120	COG0183	Belongs to the thiolase family
CY96_17125	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_17130	COG1268	BioY protein
CY96_17135	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_17140	COG1396	sequence-specific DNA binding
CY96_17180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_17190	COG5002	protein histidine kinase activity
CY96_17195	COG0400	carboxylic ester hydrolase activity
CY96_17200	COG0346	lactoylglutathione lyase activity
CY96_17210	COG0069	glutamate synthase activity
CY96_17215	COG1902	pentaerythritol trinitrate reductase activity
CY96_17220	COG1329	Transcriptional regulator
CY96_17225	COG0010	Belongs to the arginase family
CY96_17250	COG2226	methyltransferase
CY96_17275	COG4846	Membrane protein involved in cytochrome C biogenesis
CY96_17280	COG0785	Cytochrome C biogenesis protein
CY96_17305	COG1131	(ABC) transporter
CY96_17320	COG0583	DNA-binding transcription factor activity
CY96_17330	COG1346	cytolysis
CY96_17345	COG0730	response to heat
CY96_17370	COG1132	(ABC) transporter
CY96_17375	COG1132	(ABC) transporter
CY96_17410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY96_17415	COG0737	Belongs to the 5'-nucleotidase family
CY96_17425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CY96_17445	COG1695	Transcriptional regulator
CY96_17485	COG0739	heme binding
CY96_17490	COG0741	lytic transglycosylase activity
CY96_17525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CY96_17530	COG0174	glutamine synthetase
CY96_17535	COG0789	Transcriptional regulator
CY96_17540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CY96_17545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CY96_17550	COG2860	membrane
CY96_17560	COG0464	growth
CY96_17595	COG1388	LysM domain
CY96_17595	COG3584	3D domain protein
CY96_17600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY96_17600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_17600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY96_17605	COG1105	Belongs to the carbohydrate kinase PfkB family
CY96_17610	COG1349	DNA-binding transcription factor activity
CY96_17615	COG1979	alcohol dehydrogenase
CY96_17620	COG2322	membrane
CY96_17635	COG1113	amino acid transport
CY96_17645	COG1408	metallophosphoesterase
CY96_17650	COG2116	formate transmembrane transporter activity
CY96_17665	COG2217	Heavy metal translocating P-type atpase
CY96_17670	COG2608	mercury ion transmembrane transporter activity
CY96_17675	COG1937	Protein conserved in bacteria
CY96_17685	COG1464	Belongs to the NlpA lipoprotein family
CY96_17690	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CY96_17695	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CY96_17700	COG2017	converts alpha-aldose to the beta-anomer
CY96_17705	COG2207	Transcriptional regulator
CY96_17710	COG5492	domain, Protein
CY96_17720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CY96_17725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_17725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_17730	COG3716	PTS system mannose fructose sorbose family IID component
CY96_17735	COG3715	PTS system
CY96_17745	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_17750	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CY96_17755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CY96_17765	COG1414	Transcriptional regulator
CY96_17775	COG2819	hydrolase of the alpha beta superfamily
CY96_17780	COG1120	ATPase activity
CY96_17785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_17790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_17800	COG2169	Transcriptional regulator
CY96_17805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CY96_17810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CY96_17830	COG2267	carboxylic ester hydrolase activity
CY96_17835	COG5001	Diguanylate cyclase
CY96_17835	COG3300	MHYT domain
CY96_17855	COG1086	Polysaccharide biosynthesis protein
CY96_17870	COG1346	cytolysis
CY96_17880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_17890	COG0823	Involved in the tonB-independent uptake of proteins
CY96_17895	COG1404	Belongs to the peptidase S8 family
CY96_17900	COG3773	Cell wall hydrolase
CY96_17910	COG1368	sulfuric ester hydrolase activity
CY96_17915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CY96_17940	COG4550	Control of competence regulator ComK, YlbF/YmcA
CY96_17950	COG1013	pyruvate-flavodoxin oxidoreductase activity
CY96_17955	COG0674	pyruvate-flavodoxin oxidoreductase activity
CY96_17955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CY96_17965	COG2359	stage V sporulation protein S
CY96_17970	COG1692	metallophosphoesterase
CY96_17990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CY96_17995	COG1426	Protein conserved in bacteria
CY96_18010	COG0300	oxidoreductase activity
CY96_18015	COG0612	Peptidase, M16
CY96_18020	COG0612	Peptidase, M16
CY96_18045	COG2188	Transcriptional regulator
CY96_18060	COG0740	serine-type endopeptidase activity
CY96_18065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CY96_18075	COG0527	aspartate kinase activity
CY96_18080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CY96_18085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY96_18090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY96_18095	COG1873	PFAM PRC-barrel domain
CY96_18100	COG0612	Peptidase, M16
CY96_18105	COG0726	polysaccharide deacetylase
CY96_18120	COG0196	riboflavin kinase activity
CY96_18135	COG1550	Protein conserved in bacteria
CY96_18145	COG1358	cellular component organization or biogenesis
CY96_18150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CY96_18155	COG0195	Participates in both transcription termination and antitermination
CY96_18175	COG0750	zinc metalloprotease
CY96_18185	COG4589	Belongs to the CDS family
CY96_18230	COG4974	Belongs to the 'phage' integrase family
CY96_18240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CY96_18245	COG0758	DNA mediated transformation
CY96_18250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CY96_18290	COG1837	Belongs to the UPF0109 family
CY96_18300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CY96_18310	COG0552	protein localization to endoplasmic reticulum
CY96_18315	COG1196	nuclear chromosome segregation
CY96_18330	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_18335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CY96_18350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CY96_18355	COG1461	Dihydroxyacetone kinase
CY96_18360	COG1302	Protein conserved in bacteria
CY96_18375	COG1564	THIamine pyrophosphokinase
CY96_18380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CY96_18390	COG2815	serine threonine protein kinase
CY96_18390	COG0515	serine threonine protein kinase
CY96_18395	COG0631	protein serine/threonine phosphatase activity
CY96_18405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CY96_18405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CY96_18420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CY96_18425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CY96_18445	COG1561	YicC-like family, N-terminal region
CY96_18450	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CY96_18460	COG0006	proline dipeptidase activity
CY96_18470	COG3069	C4-dicarboxylate transmembrane transporter activity
CY96_18480	COG0546	phosphoglycolate phosphatase activity
CY96_18535	COG0564	pseudouridine synthase activity
CY96_18555	COG3599	regulation of cell shape
CY96_18560	COG2302	S4 RNA-binding domain
CY96_18565	COG0762	integral membrane protein
CY96_18575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CY96_18585	COG1873	PFAM PRC-barrel domain
CY96_18590	COG1191	sigma factor activity
CY96_18595	COG1191	sigma factor activity
CY96_18605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CY96_18610	COG0849	cell division
CY96_18635	COG0772	Belongs to the SEDS family
CY96_18655	COG0768	penicillin binding
CY96_18680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CY96_18700	COG1399	metal-binding, possibly nucleic acid-binding protein
CY96_18710	COG3480	Lon protease (S16) C-terminal proteolytic domain
CY96_18715	COG1752	Esterase of the alpha-beta hydrolase superfamily
CY96_18720	COG3314	Sporulation integral membrane protein YlbJ
CY96_18730	COG0742	ribosomal rna small subunit methyltransferase
CY96_18745	COG3679	Belongs to the UPF0342 family
CY96_18750	COG0406	alpha-ribazole phosphatase activity
CY96_18765	COG2340	Cysteine-rich secretory protein family
CY96_18780	COG3336	cytochrome c oxidase
CY96_18815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CY96_18820	COG0772	Belongs to the SEDS family
CY96_18830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CY96_18835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CY96_18845	COG4896	Protein conserved in bacteria
CY96_18870	COG0483	inositol monophosphate 1-phosphatase activity
CY96_18890	COG1982	Orn Lys Arg decarboxylase major
CY96_18940	COG0022	dehydrogenase e1 component
CY96_18945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY96_18960	COG0561	phosphatase activity
CY96_18970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CY96_18975	COG0569	domain protein
CY96_18995	COG0583	DNA-binding transcription factor activity
CY96_19000	COG0517	IMP dehydrogenase activity
CY96_19010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CY96_19020	COG4703	Protein of unknown function (DUF1797)
CY96_19035	COG2200	EAL domain
CY96_19040	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_19045	COG1408	metallophosphoesterase
CY96_19090	COG2814	Major facilitator Superfamily
CY96_19110	COG3209	COG3209 Rhs family protein
CY96_19120	COG2205	protein histidine kinase activity
CY96_19130	COG0436	Aminotransferase
CY96_19135	COG1609	Transcriptional regulator
CY96_19140	COG3833	ABC-type maltose transport systems, permease component
CY96_19145	COG1175	transmembrane transport
CY96_19150	COG2182	Extracellular solute-binding protein
CY96_19160	COG0366	Alpha amylase catalytic
CY96_19165	COG3842	ATPase activity
CY96_19205	COG0183	Belongs to the thiolase family
CY96_19235	COG1695	Transcriptional regulator
CY96_19240	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_19260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CY96_19265	COG0436	Aminotransferase
CY96_19300	COG2084	Dehydrogenase
CY96_19310	COG2203	Gaf domain
CY96_19310	COG2199	diguanylate cyclase activity
CY96_19315	COG0778	Nitroreductase
CY96_19340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CY96_19340	COG1263	PTS System
CY96_19340	COG2190	(PTS) system
CY96_19345	COG3711	transcriptional antiterminator
CY96_19365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CY96_19390	COG1547	Domain of unknown function (DUF309)
CY96_19395	COG0456	acetyltransferase
CY96_19400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CY96_19405	COG4086	secreted protein
CY96_19410	COG0561	phosphatase activity
CY96_19415	COG0697	spore germination
CY96_19430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CY96_19455	COG0733	neurotransmitter:sodium symporter activity
CY96_19475	COG1686	Belongs to the peptidase S11 family
CY96_19480	COG1725	Transcriptional regulator
CY96_19485	COG1131	(ABC) transporter
CY96_19500	COG1846	Transcriptional regulator
CY96_19515	COG0598	Magnesium transport protein CorA
CY96_19540	COG4974	Belongs to the 'phage' integrase family
CY96_19550	COG0735	belongs to the Fur family
CY96_19555	COG1300	Membrane
CY96_19575	COG0667	Aldo Keto reductase
CY96_19580	COG0656	L-ascorbic acid biosynthetic process
CY96_19585	COG0456	acetyltransferase
CY96_19585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CY96_19595	COG1525	nuclease
CY96_19595	COG4085	toxin activity
CY96_19595	COG0737	Belongs to the 5'-nucleotidase family
CY96_19605	COG0596	Alpha beta hydrolase
CY96_19610	COG2056	Na+-H+ antiporter family
CY96_19615	COG1609	Transcriptional regulator
CY96_19620	COG0456	acetyltransferase
CY96_19625	COG1073	alpha beta
CY96_19640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY96_19640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CY96_19645	COG0307	riboflavin synthase, alpha
CY96_19675	COG2226	methyltransferase
CY96_19675	COG1073	alpha beta
CY96_19690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CY96_19705	COG0737	Belongs to the 5'-nucleotidase family
CY96_19715	COG1522	sequence-specific DNA binding
CY96_19760	COG0300	oxidoreductase activity
CY96_19765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_19770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY96_19775	COG1760	l-serine dehydratase
CY96_19780	COG1760	l-serine dehydratase
CY96_19810	COG1285	pathogenesis
CY96_19820	COG2195	Cleaves the N-terminal amino acid of tripeptides
CY96_19825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_19840	COG1376	ErfK ybiS ycfS ynhG family protein
CY96_19845	COG4129	membrane
CY96_19850	COG1126	abc transporter atp-binding protein
CY96_19855	COG0765	amino acid transport
CY96_19860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CY96_19880	COG2323	membrane
CY96_19885	COG0772	Belongs to the SEDS family
CY96_19890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CY96_19895	COG0022	dehydrogenase e1 component
CY96_19900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CY96_19905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CY96_19915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CY96_19920	COG0280	phosphate acetyltransferase
CY96_19925	COG3290	protein histidine kinase activity
CY96_19925	COG3829	transcription factor binding
CY96_19935	COG0584	glycerophosphoryl diester phosphodiesterase
CY96_20050	COG0750	zinc metalloprotease
CY96_20055	COG0497	DNA recombination
CY96_20065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CY96_20075	COG0142	geranyltranstransferase activity
CY96_20100	COG1302	Protein conserved in bacteria
CY96_20105	COG0439	Biotin carboxylase
CY96_20110	COG0511	ligase activity, forming carbon-carbon bonds
CY96_20150	COG3854	ATPases associated with a variety of cellular activities
CY96_20175	COG0006	proline dipeptidase activity
CY96_20190	COG3872	metal-dependent enzyme
CY96_20200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CY96_20230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_20240	COG1609	Transcriptional regulator
CY96_20250	COG2076	Multidrug Resistance protein
CY96_20255	COG2076	Multidrug Resistance protein
CY96_20290	COG1725	Transcriptional regulator
CY96_20320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY96_20385	COG1459	type II secretion system
CY96_20390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CY96_20445	COG1410	methionine synthase
CY96_20445	COG0646	methionine synthase
CY96_20450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CY96_20450	COG0646	methionine synthase
CY96_20460	COG0626	cystathionine gamma-synthase activity
CY96_20465	COG0626	cystathionine gamma-synthase activity
CY96_20485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_20495	COG1940	carbohydrate kinase activity
CY96_20500	COG4483	Protein conserved in bacteria
CY96_20505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CY96_20515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CY96_20520	COG0704	Plays a role in the regulation of phosphate uptake
CY96_20530	COG0573	inorganic phosphate transmembrane transporter activity
CY96_20535	COG0573	inorganic phosphate transmembrane transporter activity
CY96_20550	COG0477	Major facilitator Superfamily
CY96_20555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CY96_20565	COG5521	maltodextrose utilization protein MalA
CY96_20580	COG0735	belongs to the Fur family
CY96_20585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CY96_20590	COG1121	(ABC) transporter
CY96_20595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_20625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CY96_20630	COG2384	SAM-dependent methyltransferase
CY96_20640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CY96_20645	COG0358	DNA primase activity
CY96_20665	COG0517	IMP dehydrogenase activity
CY96_20680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CY96_20685	COG0295	cytidine deaminase activity
CY96_20690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CY96_20700	COG1480	7TM receptor with intracellular HD hydrolase
CY96_20705	COG1702	phosphate starvation-inducible protein PhoH
CY96_20720	COG1610	YqeY-like protein
CY96_20730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CY96_20735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CY96_20765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CY96_20770	COG1733	regulation of RNA biosynthetic process
CY96_20795	COG1466	dna polymerase III delta subunit
CY96_20805	COG0658	competence protein
CY96_20805	COG2333	competence protein COMEC
CY96_20810	COG2131	deaminase
CY96_20815	COG1596	polysaccharide export
CY96_20815	COG1555	photosystem II stabilization
CY96_20820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CY96_20825	COG2226	methyltransferase
CY96_20830	COG0799	negative regulation of ribosome biogenesis
CY96_20835	COG1713	HD superfamily hydrolase involved in NAD metabolism
CY96_20845	COG1534	Rna-binding protein
CY96_20855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CY96_20860	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CY96_20875	COG1191	sigma factor activity
CY96_20885	COG1595	DNA-templated transcription, initiation
CY96_20895	COG0778	Nitroreductase
CY96_20900	COG2357	RelA SpoT domain protein
CY96_20910	COG1785	Belongs to the alkaline phosphatase family
CY96_20920	COG2267	carboxylic ester hydrolase activity
CY96_20955	COG1404	Belongs to the peptidase S8 family
CY96_20965	COG3186	Phenylalanine-4-hydroxylase
CY96_20975	COG2514	catechol 2,3-dioxygenase activity
CY96_20980	COG2259	Doxx family
CY96_21020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_21030	COG1454	alcohol dehydrogenase
CY96_21030	COG1012	belongs to the aldehyde dehydrogenase family
CY96_21035	COG0626	cystathionine gamma-synthase activity
CY96_21040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY96_21065	COG0768	penicillin binding
CY96_21100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CY96_21130	COG0628	permease
CY96_21150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CY96_21165	COG1104	cysteine desulfurase activity
CY96_21170	COG1959	2 iron, 2 sulfur cluster binding
CY96_21175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CY96_21195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CY96_21220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY96_21230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CY96_21230	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CY96_21235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CY96_21240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY96_21240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CY96_21250	COG2244	polysaccharide biosynthetic process
CY96_21255	COG2323	membrane
CY96_21265	COG1862	Preprotein translocase
CY96_21295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CY96_21325	COG0157	Belongs to the NadC ModD family
CY96_21330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CY96_21335	COG1104	cysteine desulfurase activity
CY96_21340	COG1827	regulation of RNA biosynthetic process
CY96_21345	COG2258	MOSC domain
CY96_21355	COG0077	Prephenate dehydratase
CY96_21360	COG0577	efflux transmembrane transporter activity
CY96_21365	COG0577	efflux transmembrane transporter activity
CY96_21370	COG1136	(ABC) transporter
CY96_21375	COG5002	protein histidine kinase activity
CY96_21380	COG0745	RESPONSE REGULATOR receiver
CY96_21390	COG3290	protein histidine kinase activity
CY96_21400	COG2868	ribosomal protein
CY96_21410	COG1530	ribonuclease E activity
CY96_21415	COG1994	Peptidase M50
CY96_21420	COG0739	heme binding
CY96_21425	COG2894	cell division
CY96_21440	COG1792	Involved in formation and maintenance of cell shape
CY96_21445	COG1077	Cell shape determining protein MreB Mrl
CY96_21465	COG0285	dihydrofolate synthase activity
CY96_21480	COG1388	LysM domain
CY96_21490	COG0113	porphobilinogen synthase activity
CY96_21495	COG1587	Uroporphyrinogen-III synthase
CY96_21505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CY96_21515	COG1846	Transcriptional regulator
CY96_21520	COG1764	response to oxidative stress
CY96_21535	COG1067	ATP-dependent peptidase activity
CY96_21535	COG0470	DNA polymerase III
CY96_21575	COG0457	Tetratricopeptide repeat
CY96_21605	COG0622	Phosphoesterase
CY96_21620	COG5401	PFAM Sporulation and spore germination
CY96_21635	COG2197	response regulator
CY96_21640	COG2233	PERMEase
CY96_21650	COG0402	S-adenosylhomocysteine deaminase activity
CY96_21655	COG1983	PspC domain protein
CY96_21660	COG1396	sequence-specific DNA binding
CY96_21665	COG0697	spore germination
CY96_21675	COG1959	2 iron, 2 sulfur cluster binding
CY96_21680	COG1668	transmembrane transport
CY96_21685	COG4152	abc transporter atp-binding protein
CY96_21690	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CY96_21695	COG1360	Flagellar Motor Protein
CY96_21700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CY96_21705	COG1876	peptidase activity
CY96_21710	COG0824	Thioesterase
CY96_21715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CY96_21720	COG1053	succinate dehydrogenase
CY96_21725	COG2009	succinate dehydrogenase
CY96_21730	COG1719	4-vinyl reductase, 4VR
CY96_21740	COG3118	belongs to the thioredoxin family
CY96_21745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CY96_21750	COG2086	electron transfer activity
CY96_21755	COG1024	Enoyl-CoA hydratase
CY96_21760	COG1309	transcriptional regulator
CY96_21765	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_21790	COG2318	DinB family
CY96_21820	COG1131	(ABC) transporter
CY96_21825	COG2205	protein histidine kinase activity
CY96_21830	COG0745	RESPONSE REGULATOR receiver
CY96_21840	COG4895	conserved protein (DUF2196)
CY96_21845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CY96_21855	COG4509	Sortase family
CY96_21860	COG1120	ATPase activity
CY96_21875	COG5386	Cell surface protein
CY96_21885	COG5386	Cell surface protein
CY96_21890	COG1114	Component of the transport system for branched-chain amino acids
CY96_21895	COG1187	pseudouridine synthase activity
CY96_21910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CY96_21910	COG1796	DNA polymerase
CY96_21915	COG1286	toxin biosynthetic process
CY96_21960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY96_21970	COG1418	mRNA catabolic process
CY96_21990	COG2814	Major facilitator Superfamily
CY96_21995	COG1566	PFAM secretion protein HlyD family protein
CY96_22000	COG1309	transcriptional regulator
CY96_22005	COG1363	Peptidase, m42
CY96_22030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CY96_22045	COG1484	DNA-dependent DNA replication
CY96_22050	COG3611	Membrane attachment protein
CY96_22060	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CY96_22065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY96_22075	COG1971	Probably functions as a manganese efflux pump
CY96_22085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CY96_22085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CY96_22090	COG5002	protein histidine kinase activity
CY96_22095	COG0745	RESPONSE REGULATOR receiver
CY96_22120	COG0538	isocitrate dehydrogenase activity
CY96_22125	COG0372	Belongs to the citrate synthase family
CY96_22135	COG0628	permease
CY96_22140	COG3030	protein affecting phage T7 exclusion by the F plasmid
CY96_22165	COG1725	Transcriptional regulator
CY96_22170	COG0281	malic enzyme
CY96_22175	COG0587	DNA-directed DNA polymerase activity
CY96_22190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CY96_22205	COG4109	DRTGG domain
CY96_22220	COG0006	proline dipeptidase activity
CY96_22250	COG0662	Cupin 2, conserved barrel domain protein
CY96_22265	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_22270	COG0589	response to stress
CY96_22310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_22335	COG0827	DNA restriction-modification system
CY96_22340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CY96_22345	COG3874	Sporulation protein YtfJ
CY96_22360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CY96_22370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY96_22385	COG1104	cysteine desulfurase activity
CY96_22395	COG0583	DNA-binding transcription factor activity
CY96_22400	COG0697	spore germination
CY96_22405	COG1309	transcriptional regulator
CY96_22410	COG1956	GAF domain-containing protein
CY96_22415	COG0626	cystathionine gamma-synthase activity
CY96_22470	COG1595	DNA-templated transcription, initiation
CY96_22480	COG0110	maltose O-acetyltransferase activity
CY96_22485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CY96_22490	COG0454	-acetyltransferase
CY96_22495	COG0517	IMP dehydrogenase activity
CY96_22500	COG0123	including yeast histone deacetylase and acetoin utilization protein
CY96_22515	COG0745	RESPONSE REGULATOR receiver
CY96_22520	COG5002	protein histidine kinase activity
CY96_22525	COG0666	response to abiotic stimulus
CY96_22550	COG1609	Transcriptional regulator
CY96_22555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CY96_22555	COG1605	Chorismate mutase
CY96_22560	COG4851	CamS sex pheromone cAM373 precursor
CY96_22565	COG3118	belongs to the thioredoxin family
CY96_22575	COG2309	aminopeptidase activity
CY96_22590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_22605	COG1674	ftsk spoiiie
CY96_22620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CY96_22630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY96_22635	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CY96_22640	COG1363	Peptidase, m42
CY96_22650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_22665	COG0510	thiamine kinase activity
CY96_22670	COG1523	belongs to the glycosyl hydrolase 13 family
CY96_22680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CY96_22685	COG1349	DNA-binding transcription factor activity
CY96_22690	COG1187	pseudouridine synthase activity
CY96_22695	COG2244	polysaccharide biosynthetic process
CY96_22700	COG2081	HI0933 family
CY96_22705	COG2814	Major facilitator Superfamily
CY96_22715	COG3832	glyoxalase III activity
CY96_22735	COG1329	Transcriptional regulator
CY96_22760	COG0314	molybdopterin synthase activity
CY96_22765	COG1763	Mo-molybdopterin cofactor biosynthetic process
CY96_22770	COG0303	'Molybdopterin
CY96_22780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CY96_22785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CY96_22810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CY96_22820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CY96_22865	COG2814	Major facilitator Superfamily
CY96_22870	COG0475	glutathione-regulated potassium exporter activity
CY96_22875	COG0490	domain, Protein
CY96_22880	COG0582	viral genome integration into host DNA
CY96_22890	COG1136	(ABC) transporter
CY96_22910	COG1242	4 iron, 4 sulfur cluster binding
CY96_22915	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CY96_22920	COG1794	racemase activity, acting on amino acids and derivatives
CY96_22950	COG2267	carboxylic ester hydrolase activity
CY96_22955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CY96_22960	COG0671	phosphoesterase, PA-phosphatase related
CY96_22965	COG0438	transferase activity, transferring glycosyl groups
CY96_22990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_23030	COG5002	protein histidine kinase activity
CY96_23035	COG3852	Histidine kinase
CY96_23040	COG2267	carboxylic ester hydrolase activity
CY96_23045	COG1368	sulfuric ester hydrolase activity
CY96_23065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CY96_23070	COG1116	anion transmembrane transporter activity
CY96_23075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CY96_23100	COG0494	nUDIX hydrolase
CY96_23130	COG2076	Multidrug Resistance protein
CY96_23135	COG2076	Multidrug Resistance protein
CY96_23140	COG0789	Transcriptional regulator
CY96_23155	COG0288	reversible hydration of carbon dioxide
CY96_23160	COG1271	oxidase subunit
CY96_23165	COG1294	oxidase, subunit
CY96_23180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_23200	COG1842	Phage shock protein A
CY96_23225	COG3859	Proton-coupled thiamine transporter YuaJ
CY96_23230	COG5002	protein histidine kinase activity
CY96_23235	COG0745	RESPONSE REGULATOR receiver
CY96_23265	COG1597	lipid kinase activity
CY96_23295	COG0586	Pfam SNARE associated Golgi protein
CY96_23305	COG0577	efflux transmembrane transporter activity
CY96_23310	COG1136	(ABC) transporter
CY96_23315	COG2207	Transcriptional regulator
CY96_23315	COG3708	Transcriptional regulator
CY96_23325	COG1131	(ABC) transporter
CY96_23330	COG5658	integral membrane protein
CY96_23335	COG0640	Transcriptional regulator
CY96_23340	COG0745	RESPONSE REGULATOR receiver
CY96_23345	COG2205	protein histidine kinase activity
CY96_23350	COG0577	efflux transmembrane transporter activity
CY96_23355	COG0577	efflux transmembrane transporter activity
CY96_23360	COG1136	(ABC) transporter
CY96_23365	COG0577	efflux transmembrane transporter activity
CY96_23400	COG3964	amidohydrolase
CY96_23420	COG4948	Mandelate Racemase Muconate Lactonizing
CY96_23430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CY96_23435	COG0596	Alpha beta hydrolase
CY96_23445	COG1169	isochorismate synthase
CY96_23455	COG1575	Belongs to the MenA family. Type 1 subfamily
CY96_23460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CY96_23465	COG1278	Cold shock
CY96_23490	COG0058	SHG alpha-glucan phosphorylase activity
CY96_23500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CY96_23520	COG0039	L-malate dehydrogenase activity
CY96_23615	COG0544	peptidyl-prolyl cis-trans isomerase activity
CY96_23650	COG1285	pathogenesis
CY96_23655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY96_23670	COG2155	Conserved Protein
CY96_23675	COG1098	S1 RNA binding domain
CY96_23680	COG0436	Aminotransferase
CY96_23685	COG1522	sequence-specific DNA binding
CY96_23690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CY96_23695	COG2267	carboxylic ester hydrolase activity
CY96_23705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CY96_23725	COG5018	Exonuclease
CY96_23730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY96_23745	COG0423	glycine-tRNA ligase activity
CY96_23750	COG2050	protein possibly involved in aromatic compounds catabolism
CY96_23760	COG1268	BioY protein
CY96_23765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY96_23770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CY96_23785	COG3584	3D domain protein
CY96_23800	COG1252	NADH dehydrogenase
CY96_23815	COG3708	Transcriptional regulator
CY96_23830	COG1683	Conserved Protein
CY96_23845	COG0316	Belongs to the HesB IscA family
CY96_23860	COG1252	NADH dehydrogenase
CY96_23865	COG2274	protein secretion by the type I secretion system
CY96_23870	COG0390	transport system, permease component
CY96_23875	COG2824	Alkylphosphonate utilization operon protein PhnA
CY96_23930	COG4837	Protein of unknown function (DUF1462)
CY96_23935	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CY96_23945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY96_23950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CY96_23970	COG1358	cellular component organization or biogenesis
CY96_23985	COG2249	NAD(P)H dehydrogenase (quinone) activity
CY96_23990	COG0647	UMP catabolic process
CY96_24000	COG2445	Protein of unknown function DUF86
CY96_24005	COG1494	fructose-1,6-bisphosphatase
CY96_24020	COG4470	Protein conserved in bacteria
CY96_24030	COG0789	Transcriptional regulator
CY96_24035	COG4377	Putative membrane peptidase family (DUF2324)
CY96_24060	COG0739	heme binding
CY96_24070	COG3377	Domain of unknown function (DUF1805)
CY96_24075	COG0737	Belongs to the 5'-nucleotidase family
CY96_24080	COG0719	Fe-S assembly protein
CY96_24085	COG0822	iron-sulfur transferase activity
CY96_24090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CY96_24095	COG0719	Fe-S assembly protein
CY96_24100	COG0396	ATPase activity
CY96_24105	COG1464	Belongs to the NlpA lipoprotein family
CY96_24110	COG2011	ABC-type metal ion transport system permease component
CY96_24125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CY96_24130	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CY96_24140	COG1393	Belongs to the ArsC family
CY96_24160	COG0039	L-malate dehydrogenase activity
CY96_24180	COG1309	transcriptional regulator
CY96_24185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CY96_24190	COG1960	acyl-CoA dehydrogenase activity
CY96_24195	COG0183	Belongs to the thiolase family
CY96_24200	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY96_24200	COG1024	Enoyl-CoA hydratase
CY96_24210	COG1686	Belongs to the peptidase S11 family
CY96_24225	COG0011	TIGRFAM Protein of
CY96_24230	COG0840	transmembrane signaling receptor activity
CY96_24245	COG2814	Major facilitator Superfamily
CY96_24250	COG0531	amino acid
CY96_24275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CY96_24310	COG0586	Pfam SNARE associated Golgi protein
CY96_24320	COG1376	ErfK ybiS ycfS ynhG family protein
CY96_24325	COG0745	RESPONSE REGULATOR receiver
CY96_24330	COG5002	protein histidine kinase activity
CY96_24360	COG0840	transmembrane signaling receptor activity
CY96_24365	COG2151	metal-sulfur cluster biosynthetic enzyme
CY96_24370	COG3227	Zinc metalloprotease (Elastase)
CY96_24375	COG1741	Belongs to the pirin family
CY96_24390	COG0586	Pfam SNARE associated Golgi protein
CY96_24395	COG0475	glutathione-regulated potassium exporter activity
CY96_24400	COG0490	domain, Protein
CY96_24410	COG1115	amino acid carrier protein
CY96_24430	COG1611	Belongs to the LOG family
CY96_24440	COG1528	Iron-storage protein
CY96_24445	COG2311	Membrane
CY96_24450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_24455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_24460	COG1115	amino acid carrier protein
CY96_24465	COG1115	amino acid carrier protein
CY96_24470	COG2910	NAD(P)H-binding
CY96_24490	COG0656	L-ascorbic acid biosynthetic process
CY96_24495	COG2814	Major facilitator Superfamily
CY96_24500	COG1733	regulation of RNA biosynthetic process
CY96_24510	COG1252	NADH dehydrogenase
CY96_24530	COG0840	transmembrane signaling receptor activity
CY96_24530	COG3290	protein histidine kinase activity
CY96_24565	COG0488	(ABC) transporter
CY96_24570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_24575	COG3223	Belongs to the PsiE family
CY96_24620	COG0745	RESPONSE REGULATOR receiver
CY96_24640	COG0557	exoribonuclease II activity
CY96_24645	COG1647	Serine aminopeptidase, S33
CY96_24650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY96_24655	COG1346	cytolysis
CY96_24690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CY96_24705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CY96_24715	COG1668	transmembrane transport
CY96_24720	COG4152	abc transporter atp-binding protein
CY96_24725	COG4585	Histidine kinase
CY96_24755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CY96_24770	COG2323	membrane
CY96_24790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_24800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CY96_24810	COG1051	belongs to the nudix hydrolase family
CY96_24820	COG0492	ferredoxin-NADP+ reductase activity
CY96_24825	COG0457	Tetratricopeptide repeat
CY96_24830	COG0110	maltose O-acetyltransferase activity
CY96_24850	COG1950	PFAM Membrane protein of
CY96_24860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CY96_24865	COG0556	nucleotide-excision repair
CY96_24880	COG0789	Transcriptional regulator
CY96_24900	COG0583	DNA-binding transcription factor activity
CY96_24910	COG0655	NAD(P)H dehydrogenase (quinone) activity
CY96_24925	COG1132	(ABC) transporter
CY96_24930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY96_24935	COG3409	Peptidoglycan-binding domain 1 protein
CY96_24935	COG0793	Belongs to the peptidase S41A family
CY96_24940	COG2177	Part of the ABC transporter FtsEX involved in
CY96_24945	COG2884	Cell division ATP-binding protein ftsE
CY96_24955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CY96_24975	COG1131	(ABC) transporter
CY96_25005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CY96_25010	COG1278	Cold shock
CY96_25015	COG1040	competence protein
CY96_25020	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CY96_25025	COG1388	LysM domain
CY96_25025	COG0791	NLP P60 protein
CY96_25030	COG1733	regulation of RNA biosynthetic process
CY96_25035	COG1307	EDD domain protein, DegV family
CY96_25040	COG1739	Uncharacterized protein family UPF0029
CY96_25045	COG1316	TRANSCRIPTIONal
CY96_25050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CY96_25055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CY96_25060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CY96_25070	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CY96_25070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CY96_25090	COG1486	melibiose metabolic process
CY96_25095	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY96_25100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY96_25110	COG1447	Phosphotransferase system cellobiose-specific component IIA
CY96_25120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CY96_25125	COG1301	dicarboxylic acid transport
CY96_25140	COG1511	domain protein
CY96_25145	COG0583	DNA-binding transcription factor activity
CY96_25150	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CY96_25160	COG1271	oxidase subunit
CY96_25165	COG1294	oxidase, subunit
CY96_25170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CY96_25180	COG1620	l-lactate permease
CY96_25190	COG2389	metal-binding protein
CY96_25200	COG1368	sulfuric ester hydrolase activity
CY96_25220	COG0791	NLP P60 protein
CY96_25220	COG1388	LysM domain
CY96_25230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CY96_25240	COG1215	transferase activity, transferring glycosyl groups
CY96_25250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY96_25255	COG1388	LysM domain
CY96_25255	COG3584	3D domain protein
CY96_25280	COG4715	Zinc finger, swim domain protein
CY96_25285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CY96_25315	COG1191	sigma factor activity
CY96_25325	COG0577	efflux transmembrane transporter activity
CY96_25330	COG1136	(ABC) transporter
CY96_25365	COG5002	protein histidine kinase activity
CY96_25370	COG0745	RESPONSE REGULATOR receiver
CY96_25375	COG1482	cell wall glycoprotein biosynthetic process
CY96_25380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY96_25380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_25380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CY96_25385	COG3711	transcriptional antiterminator
CY96_25385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CY96_25390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CY96_25405	COG1482	cell wall glycoprotein biosynthetic process
CY96_25410	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CY96_25410	COG0662	Cupin 2, conserved barrel domain protein
CY96_25425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CY96_25455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CY96_25460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY96_25465	COG4464	protein tyrosine phosphatase activity
CY96_25470	COG0489	protein tyrosine kinase activity
CY96_25475	COG3944	biosynthesis protein
CY96_25480	COG0489	protein tyrosine kinase activity
CY96_25495	COG1609	Transcriptional regulator
CY96_25505	COG0739	heme binding
CY96_25520	COG3279	Response regulator of the LytR AlgR family
CY96_25535	COG2385	sporulation resulting in formation of a cellular spore
CY96_25550	COG4836	Membrane
CY96_25555	COG1007	ATP synthesis coupled electron transport
CY96_25560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY96_25565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CY96_25575	COG0839	Belongs to the complex I subunit 6 family
CY96_25595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CY96_25610	COG5001	Diguanylate cyclase
CY96_25610	COG3300	MHYT domain
CY96_25665	COG0356	it plays a direct role in the translocation of protons across the membrane
CY96_25700	COG0698	ribose 5-phosphate isomerase
CY96_25715	COG2259	Doxx family
CY96_25720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY96_25740	COG0009	L-threonylcarbamoyladenylate synthase
CY96_25775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CY96_25790	COG1494	fructose-1,6-bisphosphatase
CY96_25815	COG4821	SIS domain
CY96_25825	COG3343	RNA polymerase activity
CY96_25835	COG1960	acyl-CoA dehydrogenase activity
CY96_25840	COG1960	acyl-CoA dehydrogenase activity
CY96_25845	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY96_25850	COG0183	Belongs to the thiolase family
CY96_25855	COG2181	nitrate reductase activity
CY96_25855	COG0247	lactate metabolic process
CY96_25860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CY96_25870	COG5001	Diguanylate cyclase
CY96_25870	COG3300	MHYT domain
CY96_25885	COG3227	Zinc metalloprotease (Elastase)
CY96_25890	COG2197	response regulator
CY96_25895	COG4585	Histidine kinase
CY96_25900	COG0842	Transport permease protein
CY96_25905	COG1131	(ABC) transporter
CY96_25910	COG0024	Methionine aminopeptidase
CY96_25920	COG2234	aminopeptidase activity
CY96_25940	COG1595	DNA-templated transcription, initiation
CY96_25950	COG4506	Protein conserved in bacteria
CY96_25955	COG1619	proteins homologs of microcin C7 resistance protein MccF
CY96_25975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CY96_25980	COG2814	Major facilitator Superfamily
CY96_25985	COG0789	Transcriptional regulator
CY96_25995	COG0584	glycerophosphoryl diester phosphodiesterase
CY96_26000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_26010	COG1994	Peptidase M50
CY96_26020	COG1078	dGTPase activity
CY96_26025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CY96_26030	COG1120	ATPase activity
CY96_26035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_26040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CY96_26060	COG0280	phosphate acetyltransferase
CY96_26075	COG3773	Cell wall hydrolase
CY96_26085	COG2363	Small membrane protein
CY96_26095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CY96_26100	COG2233	PERMEase
CY96_26105	COG0561	phosphatase activity
CY96_26110	COG2814	Major facilitator Superfamily
CY96_26120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CY96_26125	COG1131	(ABC) transporter
CY96_26130	COG2755	lipolytic protein G-D-S-L family
CY96_26135	COG1609	Transcriptional regulator
CY96_26145	COG0460	homoserine dehydrogenase
CY96_26165	COG1011	Hydrolase
CY96_26170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CY96_26180	COG2197	response regulator
CY96_26185	COG2203	Gaf domain
CY96_26185	COG4585	Histidine kinase
CY96_26190	COG0351	phosphomethylpyrimidine kinase
CY96_26195	COG3706	GGDEF domain
CY96_26200	COG2879	small protein
CY96_26205	COG1966	Carbon starvation protein
CY96_26210	COG3279	Response regulator of the LytR AlgR family
CY96_26215	COG0477	Major facilitator Superfamily
CY96_26225	COG0438	transferase activity, transferring glycosyl groups
CY96_26240	COG0840	transmembrane signaling receptor activity
CY96_26250	COG1607	acyl-coa hydrolase
CY96_26255	COG1216	Glycosyl transferase, family 2
CY96_26270	COG1216	Glycosyl transferase, family 2
CY96_26280	COG4485	Bacterial membrane protein, YfhO
CY96_26285	COG0463	Glycosyl transferase, family 2
CY96_26290	COG0488	(ABC) transporter
CY96_26295	COG1309	transcriptional regulator
CY96_26300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CY96_26305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CY96_26305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CY96_26310	COG0628	permease
CY96_26330	COG3275	phosphorelay sensor kinase activity
CY96_26335	COG2814	Major facilitator Superfamily
CY96_26340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CY96_26345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CY96_26365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CY96_26370	COG1272	protein, Hemolysin III
CY96_26410	COG5002	protein histidine kinase activity
CY96_26425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CY96_26430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CY96_26435	COG4853	Protein conserved in bacteria
CY96_26445	COG5002	protein histidine kinase activity
CY96_26450	COG0745	RESPONSE REGULATOR receiver
CY96_26480	COG0305	Participates in initiation and elongation during chromosome replication
CY96_26490	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CY96_26495	COG4241	membrane
CY96_26515	COG0012	GTP binding
CY96_26520	COG4481	Protein conserved in bacteria
CY96_26525	COG0668	transmembrane transport
CY96_26535	COG1475	DNA binding
CY96_26540	COG1192	Involved in chromosome partitioning
CY96_26565	COG1847	R3H domain protein
CY96_26590	COG0592	DNA-directed DNA polymerase activity
CY96_26595	COG2501	S4 domain
CY96_26605	COG0187	DNA topoisomerase II activity
CY96_26610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CY96_26635	COG0517	IMP dehydrogenase activity
CY96_26635	COG0516	GMP reductase activity
CY96_26640	COG1686	Belongs to the peptidase S11 family
CY96_26670	COG1428	Deoxynucleoside kinase
CY96_26675	COG1428	Deoxynucleoside kinase
CY96_26680	COG1335	isochorismatase
CY96_26685	COG0590	tRNA wobble adenosine to inosine editing
CY96_26690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CY96_26735	COG1982	Orn Lys Arg decarboxylase major
CY96_26745	COG0470	DNA polymerase III
CY96_26750	COG1774	PSP1 C-terminal conserved region
CY96_26760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CY96_26770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CY96_26775	COG2002	toxin-antitoxin pair type II binding
CY96_26785	COG0084	hydrolase, TatD family'
CY96_26805	COG4466	Protein conserved in bacteria
CY96_26820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CY96_26825	COG0251	oxidation-reduction process
CY96_26840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CY96_26855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CY96_26860	COG2002	toxin-antitoxin pair type II binding
CY96_26865	COG2244	polysaccharide biosynthetic process
CY96_26870	COG3956	TIGRFAM MazG family protein
CY96_26875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CY96_26895	COG1098	S1 RNA binding domain
CY96_26910	COG2208	phosphoserine phosphatase activity
CY96_26925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CY96_26940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CY96_26945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CY96_26950	COG0512	Glutamine amidotransferase of anthranilate synthase
CY96_26955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CY96_26960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CY96_26965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CY96_26970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CY96_26975	COG1396	sequence-specific DNA binding
CY96_26980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CY96_27010	COG3880	PFAM UvrB UvrC protein
CY96_27020	COG0542	response to heat
CY96_27025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CY96_27035	COG4956	integral membrane protein (PIN domain superfamily)
CY96_27055	COG1045	serine acetyltransferase
CY96_27070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CY96_27075	COG3688	RNA-binding protein containing a PIN domain
CY96_27085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CY96_27090	COG0250	Participates in transcription elongation, termination and antitermination
CY96_27115	COG2813	Specifically methylates the guanine in position
CY96_27130	COG1358	cellular component organization or biogenesis
CY96_27235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CY96_27260	COG0201	protein transport
CY96_27270	COG0024	Methionine aminopeptidase
CY96_27280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CY96_27315	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CY96_27340	COG0860	N-Acetylmuramoyl-L-alanine amidase
CY96_27345	COG0489	protein tyrosine kinase activity
CY96_27355	COG2194	sulfuric ester hydrolase activity
CY96_27360	COG0726	polysaccharide deacetylase
CY96_27495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CY96_27510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_27515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CY96_27530	COG1404	Belongs to the peptidase S8 family
CY96_27540	COG4585	Histidine kinase
CY96_27555	COG1309	transcriptional regulator
CY96_27590	COG0367	asparagine synthase
CY96_27595	COG1309	transcriptional regulator
CY96_27675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_27680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CY96_27685	COG1687	branched-chain amino acid
CY96_27710	COG2233	PERMEase
CY96_27715	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CY96_27720	COG0288	reversible hydration of carbon dioxide
CY96_27725	COG1522	sequence-specific DNA binding
CY96_27755	COG0542	response to heat
CY96_27760	COG0494	nUDIX hydrolase
CY96_27765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CY96_27775	COG0457	Tetratricopeptide repeat
CY96_27900	COG2814	Major facilitator Superfamily
CY96_27920	COG1082	Xylose isomerase domain protein TIM barrel
CY96_27925	COG0673	inositol 2-dehydrogenase activity
CY96_27930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CY96_27935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CY96_27945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CY96_27950	COG0662	Cupin 2, conserved barrel domain protein
CY96_27955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CY96_27960	COG1349	DNA-binding transcription factor activity
CY96_27965	COG0546	phosphoglycolate phosphatase activity
CY96_28355	COG2311	Membrane
CY96_28365	COG2002	toxin-antitoxin pair type II binding
CY96_28395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CY96_28425	COG0584	glycerophosphoryl diester phosphodiesterase
CY96_28475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CY96_28490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY96_28495	COG0438	transferase activity, transferring glycosyl groups
CY96_28500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CY96_28515	COG0438	transferase activity, transferring glycosyl groups
CY96_28520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CY96_28525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CY96_28530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CY96_28560	COG2002	toxin-antitoxin pair type II binding
CY96_28580	COG2169	Transcriptional regulator
CY96_28625	COG0076	glutamate decarboxylase activity
CY96_28690	COG3409	Peptidoglycan-binding domain 1 protein
CY96_28690	COG5632	N-Acetylmuramoyl-L-alanine amidase
CY96_28695	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CY96_28740	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_28775	COG0577	efflux transmembrane transporter activity
CY96_28810	COG1522	sequence-specific DNA binding
CY96_28820	COG3409	Peptidoglycan-binding domain 1 protein
CY96_28820	COG5632	N-Acetylmuramoyl-L-alanine amidase
CY96_28825	COG0506	proline dehydrogenase activity
CY96_28830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_28905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CY96_28915	COG4641	Protein conserved in bacteria
CY96_28935	COG2124	cytochrome p450
CY96_28940	COG1846	Transcriptional regulator
CY96_28945	COG1846	Transcriptional regulator
CY96_28950	COG2814	Major facilitator Superfamily
CY96_28960	COG2963	transposase activity
CY96_28965	COG2801	Transposase and inactivated derivatives
CY96_28970	COG4499	WXG100 protein secretion system (Wss), protein YukC
CY96_28970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CY96_28975	COG1923	regulation of RNA biosynthetic process
CY96_29000	COG1522	sequence-specific DNA binding
CY96_29010	COG2184	nucleotidyltransferase activity
CY96_29015	COG0814	amino acid
CY96_29035	COG3316	Transposase and inactivated derivatives
CY96_29050	COG1533	DNA photolyase activity
CY96_29070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CY96_29085	COG0697	spore germination
CY96_29090	COG2801	Transposase and inactivated derivatives
CY96_29100	COG0697	spore germination
CY96_29105	COG1802	Transcriptional regulator
CY96_29120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CY96_29135	COG2323	membrane
CY96_29160	COG0726	polysaccharide deacetylase
CY96_29185	COG1378	Sugar-specific transcriptional regulator TrmB
CY96_29220	COG0506	proline dehydrogenase activity
CY96_29225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CY96_29245	COG1131	(ABC) transporter
CY96_29280	COG2259	Doxx family
CY96_29285	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_29310	COG2814	Major facilitator Superfamily
CY96_29345	COG0823	Involved in the tonB-independent uptake of proteins
CY96_29350	COG3397	chitin binding
CY96_29360	COG0697	spore germination
CY96_29415	COG0457	Tetratricopeptide repeat
CY96_29480	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CY96_29515	COG5632	N-Acetylmuramoyl-L-alanine amidase
CY96_29515	COG3409	Peptidoglycan-binding domain 1 protein
CY96_29550	COG1132	(ABC) transporter
CY96_29570	COG1475	DNA binding
CY96_29625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CY96_29630	COG3321	synthase
CY96_29630	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_29630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY96_29630	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_29630	COG0300	oxidoreductase activity
CY96_29645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CY96_29650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CY96_29665	COG1960	acyl-CoA dehydrogenase activity
CY96_29685	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_29685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY96_29685	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_29685	COG3321	synthase
CY96_29685	COG0300	oxidoreductase activity
CY96_29685	COG0318	PFAM AMP-dependent synthetase and ligase
CY96_29685	COG0300	oxidoreductase activity
CY96_29685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CY96_29685	COG1028	Short-chain dehydrogenase reductase Sdr
CY96_29685	COG3321	synthase
CY96_29695	COG3279	Response regulator of the LytR AlgR family
CY96_29740	COG0667	Aldo Keto reductase
CY96_29905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP