locus-tag	class	description
DTO10_00030	COG3942	CHAP domain
DTO10_00030	COG1388	LysM domain
DTO10_00055	COG2244	polysaccharide biosynthetic process
DTO10_00085	COG0583	DNA-binding transcription factor activity
DTO10_00095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DTO10_00100	COG1174	glycine betaine transport
DTO10_00105	COG1732	Glycine betaine
DTO10_00110	COG1174	glycine betaine transport
DTO10_00115	COG0517	IMP dehydrogenase activity
DTO10_00115	COG1125	glycine betaine transport
DTO10_00120	COG1960	acyl-CoA dehydrogenase activity
DTO10_00125	COG2764	glyoxalase bleomycin resistance protein dioxygenase
DTO10_00130	COG2801	Transposase and inactivated derivatives
DTO10_00135	COG2259	Doxx family
DTO10_00140	COG0501	Belongs to the peptidase M48B family
DTO10_00160	COG0702	epimerase
DTO10_00165	COG0406	alpha-ribazole phosphatase activity
DTO10_00185	COG0708	Exodeoxyribonuclease III
DTO10_00190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_00195	COG0297	glycogen (starch) synthase activity
DTO10_00200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DTO10_00205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DTO10_00210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DTO10_00230	COG3663	DNA glycosylase
DTO10_00235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_00240	COG0791	NLP P60 protein
DTO10_00240	COG1388	LysM domain
DTO10_00255	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_00260	COG3835	regulator
DTO10_00265	COG0730	response to heat
DTO10_00290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DTO10_00295	COG0529	Catalyzes the synthesis of activated sulfate
DTO10_00300	COG2046	Belongs to the sulfate adenylyltransferase family
DTO10_00305	COG0175	sulfate reduction
DTO10_00315	COG0431	NADPH-dependent FMN reductase
DTO10_00330	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DTO10_00335	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DTO10_00340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_00355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_00360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_00370	COG1164	Oligoendopeptidase f
DTO10_00380	COG3403	YqcI/YcgG family
DTO10_00395	COG2197	response regulator
DTO10_00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DTO10_00415	COG2116	formate transmembrane transporter activity
DTO10_00420	COG0628	permease
DTO10_00430	COG1376	ErfK ybiS ycfS ynhG family protein
DTO10_00450	COG0765	amino acid transport
DTO10_00455	COG0765	amino acid transport
DTO10_00460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_00465	COG1126	abc transporter atp-binding protein
DTO10_00475	COG2323	membrane
DTO10_00485	COG0679	Auxin Efflux Carrier
DTO10_00490	COG0590	tRNA wobble adenosine to inosine editing
DTO10_00500	COG2706	6-phosphogluconolactonase activity
DTO10_00505	COG2356	endonuclease I
DTO10_00510	COG0494	nUDIX hydrolase
DTO10_00515	COG0737	Belongs to the 5'-nucleotidase family
DTO10_00525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_00530	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_00535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_00540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_00545	COG1278	Cold shock
DTO10_00550	COG1024	Enoyl-CoA hydratase
DTO10_00555	COG4608	Belongs to the ABC transporter superfamily
DTO10_00560	COG0444	Belongs to the ABC transporter superfamily
DTO10_00565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_00570	COG0601	transmembrane transport
DTO10_00575	COG4166	transmembrane transport
DTO10_00600	COG2176	DNA-directed DNA polymerase activity
DTO10_00605	COG1511	domain protein
DTO10_00615	COG0561	phosphatase activity
DTO10_00620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DTO10_00630	COG1113	amino acid transport
DTO10_00635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DTO10_00645	COG3852	Histidine kinase
DTO10_00655	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_00660	COG1335	isochorismatase
DTO10_00670	COG0861	Integral membrane protein TerC family
DTO10_00675	COG0246	Mannitol dehydrogenase
DTO10_00680	COG1063	alcohol dehydrogenase
DTO10_00685	COG2721	sulfolactate sulfo-lyase activity
DTO10_00690	COG2207	Transcriptional regulator
DTO10_00695	COG2271	Major facilitator Superfamily
DTO10_00700	COG1609	Transcriptional regulator
DTO10_00705	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_00715	COG1063	alcohol dehydrogenase
DTO10_00720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DTO10_00735	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_00745	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DTO10_00750	COG1691	(AIR) carboxylase
DTO10_00755	COG1606	tRNA processing
DTO10_00765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_00770	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_00785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DTO10_00790	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_00795	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_00800	COG2721	sulfolactate sulfo-lyase activity
DTO10_00815	COG1414	Transcriptional regulator
DTO10_00820	COG0129	dihydroxy-acid dehydratase activity
DTO10_00830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_00835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DTO10_00840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DTO10_00845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_00855	COG1132	(ABC) transporter
DTO10_00870	COG3858	chitin binding
DTO10_00870	COG1388	LysM domain
DTO10_00875	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_00885	COG1937	Protein conserved in bacteria
DTO10_00895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DTO10_00900	COG0400	carboxylic ester hydrolase activity
DTO10_00905	COG0346	lactoylglutathione lyase activity
DTO10_00910	COG0346	lactoylglutathione lyase activity
DTO10_00925	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_00930	COG1764	response to oxidative stress
DTO10_00960	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DTO10_00965	COG1733	regulation of RNA biosynthetic process
DTO10_00970	COG0492	ferredoxin-NADP+ reductase activity
DTO10_00985	COG0823	Involved in the tonB-independent uptake of proteins
DTO10_00985	COG1506	peptidase
DTO10_00985	COG4946	Tricorn protease homolog
DTO10_00990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DTO10_00995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_01000	COG1131	(ABC) transporter
DTO10_01010	COG2814	Major facilitator Superfamily
DTO10_01015	COG5002	protein histidine kinase activity
DTO10_01020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_01035	COG0514	ATP-dependent DNA helicase (RecQ)
DTO10_01040	COG1388	LysM domain
DTO10_01040	COG3584	3D domain protein
DTO10_01055	COG3546	catalase activity
DTO10_01060	COG2996	Protein conserved in bacteria
DTO10_01065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DTO10_01080	COG1247	-acetyltransferase
DTO10_01085	COG3973	AAA domain
DTO10_01090	COG0488	(ABC) transporter
DTO10_01100	COG0477	Major facilitator Superfamily
DTO10_01105	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_01110	COG1309	transcriptional regulator
DTO10_01115	COG2268	Band 7 protein
DTO10_01120	COG1585	Membrane protein implicated in regulation of membrane protease activity
DTO10_01125	COG1268	BioY protein
DTO10_01135	COG1272	protein, Hemolysin III
DTO10_01140	COG3773	Cell wall hydrolase
DTO10_01145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_01150	COG0432	Pfam Uncharacterised protein family UPF0047
DTO10_01160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DTO10_01160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_01160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DTO10_01165	COG1105	Belongs to the carbohydrate kinase PfkB family
DTO10_01170	COG1349	DNA-binding transcription factor activity
DTO10_01175	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_01180	COG0567	Dehydrogenase, E1 component
DTO10_01185	COG3384	dioxygenase
DTO10_01195	COG0646	methionine synthase
DTO10_01195	COG1410	methionine synthase
DTO10_01200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DTO10_01200	COG0646	methionine synthase
DTO10_01205	COG2258	MOSC domain
DTO10_01210	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DTO10_01215	COG3285	dna ligase
DTO10_01215	COG1793	dna ligase
DTO10_01230	COG0288	reversible hydration of carbon dioxide
DTO10_01260	COG1346	cytolysis
DTO10_01290	COG0668	transmembrane transport
DTO10_01295	COG0534	Mate efflux family protein
DTO10_01300	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_01310	COG2340	Cysteine-rich secretory protein family
DTO10_01325	COG5002	protein histidine kinase activity
DTO10_01330	COG0745	RESPONSE REGULATOR receiver
DTO10_01350	COG0523	cobalamin synthesis protein
DTO10_01355	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DTO10_01360	COG0235	Class ii aldolase
DTO10_01365	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DTO10_01370	COG1850	ribulose-bisphosphate carboxylase activity
DTO10_01375	COG0436	Aminotransferase
DTO10_01380	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DTO10_01385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DTO10_01390	COG1316	TRANSCRIPTIONal
DTO10_01395	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_01395	COG0793	Belongs to the peptidase S41A family
DTO10_01400	COG0813	purine-nucleoside phosphorylase activity
DTO10_01415	COG4191	Histidine kinase
DTO10_01420	COG4479	Belongs to the UPF0346 family
DTO10_01425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DTO10_01450	COG1509	lysine 2,3-aminomutase activity
DTO10_01455	COG3829	transcription factor binding
DTO10_01460	COG0456	acetyltransferase
DTO10_01465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_01470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_01475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_01480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_01490	COG1619	proteins homologs of microcin C7 resistance protein MccF
DTO10_01505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_01525	COG2755	lipolytic protein G-D-S-L family
DTO10_01530	COG1999	signal sequence binding
DTO10_01545	COG0805	protein transport
DTO10_01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_01555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DTO10_01560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DTO10_01580	COG0861	Integral membrane protein TerC family
DTO10_01590	COG0405	Gamma-glutamyltransferase
DTO10_01595	COG2136	Putative SAM-dependent methyltransferase
DTO10_01595	COG2521	methyltransferase
DTO10_01605	COG0129	dihydroxy-acid dehydratase activity
DTO10_01610	COG1413	lyase activity
DTO10_01615	COG0488	(ABC) transporter
DTO10_01620	COG1418	mRNA catabolic process
DTO10_01625	COG1307	EDD domain protein, DegV family
DTO10_01630	COG0386	Belongs to the glutathione peroxidase family
DTO10_01640	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DTO10_01650	COG2226	methyltransferase
DTO10_01655	COG1321	iron dependent repressor
DTO10_01710	COG1876	peptidase activity
DTO10_01715	COG2132	Multicopper oxidase
DTO10_01760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DTO10_01795	COG0753	catalase activity
DTO10_01805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DTO10_01810	COG3739	integral membrane protein
DTO10_01815	COG3655	Transcriptional regulator
DTO10_01835	COG2124	cytochrome p450
DTO10_01845	COG0666	response to abiotic stimulus
DTO10_01850	COG0590	tRNA wobble adenosine to inosine editing
DTO10_01855	COG0745	RESPONSE REGULATOR receiver
DTO10_01860	COG5002	protein histidine kinase activity
DTO10_01900	COG1511	domain protein
DTO10_01905	COG1309	transcriptional regulator
DTO10_01930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DTO10_01940	COG1959	2 iron, 2 sulfur cluster binding
DTO10_01945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DTO10_01955	COG0328	RNA-DNA hybrid ribonuclease activity
DTO10_01960	COG0328	RNA-DNA hybrid ribonuclease activity
DTO10_01975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_01990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DTO10_01995	COG1755	Isoprenylcysteine carboxyl methyltransferase
DTO10_02000	COG3424	synthase
DTO10_02005	COG2233	PERMEase
DTO10_02010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_02020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DTO10_02025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DTO10_02030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DTO10_02035	COG1199	ATP-dependent helicase activity
DTO10_02040	COG1278	Cold shock
DTO10_02045	COG0116	Belongs to the methyltransferase superfamily
DTO10_02060	COG3599	regulation of cell shape
DTO10_02075	COG3359	exonuclease
DTO10_02080	COG1111	helicase
DTO10_02080	COG1205	dead DEAH box helicase
DTO10_02085	COG2267	carboxylic ester hydrolase activity
DTO10_02120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_02120	COG4499	WXG100 protein secretion system (Wss), protein YukC
DTO10_02130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DTO10_02135	COG3935	DnaD domain protein
DTO10_02140	COG0017	Asparaginyl-tRNA synthetase
DTO10_02145	COG0436	Aminotransferase
DTO10_02160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DTO10_02160	COG1199	ATP-dependent helicase activity
DTO10_02165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DTO10_02175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DTO10_02185	COG0617	tRNA 3'-terminal CCA addition
DTO10_02190	COG0438	transferase activity, transferring glycosyl groups
DTO10_02195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DTO10_02200	COG1803	Methylglyoxal synthase
DTO10_02205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DTO10_02210	COG1694	Mazg nucleotide pyrophosphohydrolase
DTO10_02215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_02220	COG2738	Putative neutral zinc metallopeptidase
DTO10_02230	COG4347	Protein of unknown function (DUF1405)
DTO10_02255	COG5582	Belongs to the UPF0302 family
DTO10_02260	COG0457	Tetratricopeptide repeat
DTO10_02270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DTO10_02275	COG0287	Prephenate dehydrogenase
DTO10_02280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_02285	COG4401	Chorismate mutase type I
DTO10_02290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DTO10_02295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DTO10_02300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DTO10_02305	COG0105	UTP biosynthetic process
DTO10_02310	COG0142	geranyltranstransferase activity
DTO10_02315	COG2226	methyltransferase
DTO10_02320	COG0142	geranyltranstransferase activity
DTO10_02330	COG0302	gtp cyclohydrolase
DTO10_02335	COG0776	regulation of translation
DTO10_02340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DTO10_02360	COG3829	transcription factor binding
DTO10_02360	COG3290	protein histidine kinase activity
DTO10_02365	COG0531	amino acid
DTO10_02390	COG1304	FMN binding
DTO10_02395	COG0539	negative regulation of cytoplasmic translation
DTO10_02405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DTO10_02420	COG2959	enzyme of heme biosynthesis
DTO10_02425	COG3773	Cell wall hydrolase
DTO10_02425	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_02430	COG2339	peptidase activity
DTO10_02440	COG0492	ferredoxin-NADP+ reductase activity
DTO10_02445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_02450	COG4862	establishment of competence for transformation
DTO10_02460	COG1408	metallophosphoesterase
DTO10_02475	COG1266	CAAX protease self-immunity
DTO10_02480	COG0514	ATP-dependent DNA helicase (RecQ)
DTO10_02485	COG4955	Helix-turn-helix domain
DTO10_02495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DTO10_02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DTO10_02510	COG1595	DNA-templated transcription, initiation
DTO10_02515	COG5002	protein histidine kinase activity
DTO10_02520	COG0745	RESPONSE REGULATOR receiver
DTO10_02525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DTO10_02530	COG1333	cytochrome c biogenesis protein
DTO10_02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_02540	COG1187	pseudouridine synthase activity
DTO10_02550	COG2715	membrane protein required for spore maturation
DTO10_02555	COG1686	Belongs to the peptidase S11 family
DTO10_02565	COG0450	alkyl hydroperoxide reductase
DTO10_02570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DTO10_02585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DTO10_02600	COG1547	Domain of unknown function (DUF309)
DTO10_02610	COG4086	secreted protein
DTO10_02620	COG0697	spore germination
DTO10_02640	COG2252	PERMEase
DTO10_02650	COG2172	sigma factor antagonist activity
DTO10_02660	COG1686	Belongs to the peptidase S11 family
DTO10_02680	COG4974	Belongs to the 'phage' integrase family
DTO10_02690	COG0735	belongs to the Fur family
DTO10_02695	COG1300	Membrane
DTO10_02705	COG1379	DNA repair
DTO10_02720	COG0667	Aldo Keto reductase
DTO10_02725	COG1764	response to oxidative stress
DTO10_02730	COG1846	Transcriptional regulator
DTO10_02740	COG1073	alpha beta
DTO10_02745	COG4918	Iron-sulphur cluster biosynthesis
DTO10_02760	COG1309	transcriptional regulator
DTO10_02770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DTO10_02775	COG0791	NLP P60 protein
DTO10_02775	COG1388	LysM domain
DTO10_02785	COG0300	oxidoreductase activity
DTO10_02790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_02795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_02805	COG0789	Transcriptional regulator
DTO10_02810	COG1116	anion transmembrane transporter activity
DTO10_02810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_02830	COG1234	tRNA 3'-trailer cleavage
DTO10_02835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DTO10_02840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DTO10_02845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DTO10_02850	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_02855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DTO10_02860	COG0346	lactoylglutathione lyase activity
DTO10_02865	COG1376	ErfK ybiS ycfS ynhG family protein
DTO10_02870	COG4129	membrane
DTO10_02875	COG1126	abc transporter atp-binding protein
DTO10_02880	COG0765	amino acid transport
DTO10_02885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_02900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_02900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_02910	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_02915	COG0022	dehydrogenase e1 component
DTO10_02920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_02925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_02935	COG3290	protein histidine kinase activity
DTO10_02935	COG3829	transcription factor binding
DTO10_02945	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_02955	COG0745	RESPONSE REGULATOR receiver
DTO10_02960	COG0750	zinc metalloprotease
DTO10_02965	COG0497	DNA recombination
DTO10_02970	COG1438	arginine binding
DTO10_02975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DTO10_02980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DTO10_02990	COG1722	exodeoxyribonuclease VII activity
DTO10_02995	COG1570	exodeoxyribonuclease VII activity
DTO10_03000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DTO10_03005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DTO10_03010	COG1302	Protein conserved in bacteria
DTO10_03015	COG0439	Biotin carboxylase
DTO10_03020	COG0511	ligase activity, forming carbon-carbon bonds
DTO10_03060	COG3854	ATPases associated with a variety of cellular activities
DTO10_03065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DTO10_03070	COG0006	proline dipeptidase activity
DTO10_03085	COG3872	metal-dependent enzyme
DTO10_03095	COG1752	Esterase of the alpha-beta hydrolase superfamily
DTO10_03110	COG2814	Major facilitator Superfamily
DTO10_03115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_03120	COG0095	Lipoate-protein ligase
DTO10_03125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_03135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_03140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DTO10_03145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_03180	COG4537	Required for transformation and DNA binding
DTO10_03185	COG1459	type II secretion system
DTO10_03190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DTO10_03195	COG1393	Belongs to the ArsC family
DTO10_03215	COG1473	amidohydrolase
DTO10_03220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_03240	COG1368	sulfuric ester hydrolase activity
DTO10_03245	COG1940	carbohydrate kinase activity
DTO10_03260	COG0457	Tetratricopeptide repeat
DTO10_03260	COG0705	Rhomboid family
DTO10_03275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DTO10_03280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_03300	COG0704	Plays a role in the regulation of phosphate uptake
DTO10_03310	COG0581	inorganic phosphate transmembrane transporter activity
DTO10_03315	COG0573	inorganic phosphate transmembrane transporter activity
DTO10_03320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DTO10_03330	COG0477	Major facilitator Superfamily
DTO10_03340	COG2839	Protein conserved in bacteria
DTO10_03345	COG5521	maltodextrose utilization protein MalA
DTO10_03355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DTO10_03360	COG4709	membrane
DTO10_03365	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DTO10_03370	COG0735	belongs to the Fur family
DTO10_03375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_03380	COG1121	(ABC) transporter
DTO10_03390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DTO10_03395	COG0513	Belongs to the DEAD box helicase family
DTO10_03410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DTO10_03415	COG2384	SAM-dependent methyltransferase
DTO10_03430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DTO10_03435	COG0358	DNA primase activity
DTO10_03440	COG1671	Belongs to the UPF0178 family
DTO10_03445	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DTO10_03450	COG0517	IMP dehydrogenase activity
DTO10_03455	COG0751	glycine-tRNA ligase activity
DTO10_03460	COG0752	glycyl-tRNA synthetase alpha subunit
DTO10_03465	COG1381	Involved in DNA repair and RecF pathway recombination
DTO10_03475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DTO10_03480	COG0295	cytidine deaminase activity
DTO10_03485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DTO10_03490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DTO10_03495	COG1480	7TM receptor with intracellular HD hydrolase
DTO10_03500	COG1702	phosphate starvation-inducible protein PhoH
DTO10_03520	COG4864	UPF0365 protein
DTO10_03525	COG1030	water channel activity
DTO10_03530	COG1610	YqeY-like protein
DTO10_03535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DTO10_03540	COG1283	sodium-dependent phosphate transmembrane transporter activity
DTO10_03545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DTO10_03550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DTO10_03555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DTO10_03560	COG2264	protein methyltransferase activity
DTO10_03565	COG0484	heat shock protein binding
DTO10_03570	COG0443	Heat shock 70 kDa protein
DTO10_03575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DTO10_03585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DTO10_03600	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_03610	COG0268	Binds directly to 16S ribosomal RNA
DTO10_03615	COG1466	dna polymerase III delta subunit
DTO10_03625	COG2333	competence protein COMEC
DTO10_03625	COG0658	competence protein
DTO10_03630	COG2131	deaminase
DTO10_03635	COG1596	polysaccharide export
DTO10_03635	COG1555	photosystem II stabilization
DTO10_03640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_03645	COG2226	methyltransferase
DTO10_03650	COG0799	negative regulation of ribosome biogenesis
DTO10_03655	COG1713	HD superfamily hydrolase involved in NAD metabolism
DTO10_03660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DTO10_03665	COG1534	Rna-binding protein
DTO10_03675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DTO10_03680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DTO10_03690	COG0688	phosphatidylethanolamine metabolic process
DTO10_03695	COG1183	phosphatidylcholine synthase activity
DTO10_03730	COG0626	cystathionine gamma-synthase activity
DTO10_03735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_03760	COG0768	penicillin binding
DTO10_03765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DTO10_03770	COG0572	uridine kinase
DTO10_03790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DTO10_03795	COG3906	Belongs to the UPF0473 family
DTO10_03800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DTO10_03815	COG0628	permease
DTO10_03825	COG3881	PFAM PRC-barrel domain
DTO10_03835	COG1704	LemA family
DTO10_03840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DTO10_03850	COG0482	sulfurtransferase activity
DTO10_03855	COG1104	cysteine desulfurase activity
DTO10_03860	COG1959	2 iron, 2 sulfur cluster binding
DTO10_03870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DTO10_03885	COG1131	(ABC) transporter
DTO10_03890	COG1725	Transcriptional regulator
DTO10_03900	COG1316	TRANSCRIPTIONal
DTO10_03925	COG3944	biosynthesis protein
DTO10_03930	COG0489	protein tyrosine kinase activity
DTO10_03935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DTO10_03940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DTO10_03955	COG1215	transferase activity, transferring glycosyl groups
DTO10_03980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DTO10_04000	COG0438	transferase activity, transferring glycosyl groups
DTO10_04000	COG0297	glycogen (starch) synthase activity
DTO10_04020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_04030	COG4464	protein tyrosine phosphatase activity
DTO10_04035	COG0489	protein tyrosine kinase activity
DTO10_04040	COG3944	biosynthesis protein
DTO10_04065	COG2814	Major facilitator Superfamily
DTO10_04095	COG0411	ABC transporter
DTO10_04105	COG0559	Belongs to the binding-protein-dependent transport system permease family
DTO10_04120	COG0411	ABC transporter
DTO10_04130	COG0559	Belongs to the binding-protein-dependent transport system permease family
DTO10_04140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DTO10_04165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DTO10_04170	COG0124	histidyl-tRNA synthetase
DTO10_04175	COG4991	sh3 domain protein
DTO10_04175	COG3103	Sh3 type 3 domain protein
DTO10_04175	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_04180	COG1490	D-aminoacyl-tRNA deacylase activity
DTO10_04185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DTO10_04190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_04195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DTO10_04195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DTO10_04200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DTO10_04200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DTO10_04210	COG2244	polysaccharide biosynthetic process
DTO10_04215	COG2323	membrane
DTO10_04225	COG1862	Preprotein translocase
DTO10_04235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DTO10_04295	COG1122	ATPase activity
DTO10_04300	COG1129	ABC transporter
DTO10_04305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_04335	COG0157	Belongs to the NadC ModD family
DTO10_04340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DTO10_04345	COG1104	cysteine desulfurase activity
DTO10_04350	COG1827	regulation of RNA biosynthetic process
DTO10_04355	COG0077	Prephenate dehydratase
DTO10_04360	COG4492	Belongs to the UPF0735 family
DTO10_04365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DTO10_04370	COG3290	protein histidine kinase activity
DTO10_04380	COG2868	ribosomal protein
DTO10_04385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DTO10_04390	COG1530	ribonuclease E activity
DTO10_04395	COG1994	Peptidase M50
DTO10_04400	COG0739	heme binding
DTO10_04405	COG1098	S1 RNA binding domain
DTO10_04410	COG2894	cell division
DTO10_04425	COG1792	Involved in formation and maintenance of cell shape
DTO10_04430	COG1077	Cell shape determining protein MreB Mrl
DTO10_04435	COG2003	Belongs to the UPF0758 family
DTO10_04450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DTO10_04455	COG0285	dihydrofolate synthase activity
DTO10_04460	COG0189	ligase activity
DTO10_04470	COG0525	valine-tRNA ligase activity
DTO10_04480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_04485	COG1388	LysM domain
DTO10_04485	COG1388	LysM domain
DTO10_04490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DTO10_04495	COG0113	porphobilinogen synthase activity
DTO10_04505	COG0181	hydroxymethylbilane synthase activity
DTO10_04510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DTO10_04525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DTO10_04530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DTO10_04535	COG1067	ATP-dependent peptidase activity
DTO10_04535	COG0470	DNA polymerase III
DTO10_04545	COG0544	peptidyl-prolyl cis-trans isomerase activity
DTO10_04555	COG0066	3-isopropylmalate dehydratase activity
DTO10_04560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DTO10_04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_04575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DTO10_04580	COG0440	acetolactate synthase activity
DTO10_04585	COG0028	Belongs to the TPP enzyme family
DTO10_04595	COG0772	Belongs to the SEDS family
DTO10_04655	COG0622	Phosphoesterase
DTO10_04660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DTO10_04680	COG5401	PFAM Sporulation and spore germination
DTO10_04695	COG1846	Transcriptional regulator
DTO10_04700	COG2197	response regulator
DTO10_04705	COG0824	Thioesterase
DTO10_04735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DTO10_04740	COG1053	succinate dehydrogenase
DTO10_04745	COG2009	succinate dehydrogenase
DTO10_04750	COG1719	4-vinyl reductase, 4VR
DTO10_04765	COG3118	belongs to the thioredoxin family
DTO10_04770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DTO10_04775	COG2086	electron transfer activity
DTO10_04780	COG1024	Enoyl-CoA hydratase
DTO10_04785	COG1309	transcriptional regulator
DTO10_04790	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_04800	COG3766	membrane
DTO10_04805	COG1193	negative regulation of DNA recombination
DTO10_04810	COG1796	DNA polymerase
DTO10_04810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DTO10_04815	COG1286	toxin biosynthetic process
DTO10_04820	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DTO10_04825	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DTO10_04835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DTO10_04835	COG0072	phenylalanine-tRNA ligase activity
DTO10_04840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DTO10_04845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DTO10_04870	COG0247	lactate metabolic process
DTO10_04875	COG0277	FAD linked oxidase domain protein
DTO10_04880	COG3835	regulator
DTO10_04885	COG1620	l-lactate permease
DTO10_04890	COG2186	Transcriptional regulator
DTO10_04895	COG0247	lactate metabolic process
DTO10_04900	COG1139	Iron-sulfur cluster binding protein
DTO10_04905	COG1556	Lactate utilization protein
DTO10_04910	COG1363	Peptidase, m42
DTO10_04930	COG3326	Membrane
DTO10_04935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DTO10_04945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DTO10_04955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DTO10_04965	COG1484	DNA-dependent DNA replication
DTO10_04970	COG3611	Membrane attachment protein
DTO10_04975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DTO10_04980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DTO10_04985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DTO10_04995	COG1971	Probably functions as a manganese efflux pump
DTO10_05000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DTO10_05005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_05005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DTO10_05010	COG0330	HflC and HflK could
DTO10_05015	COG0330	HflC and HflK could
DTO10_05020	COG5002	protein histidine kinase activity
DTO10_05025	COG0745	RESPONSE REGULATOR receiver
DTO10_05035	COG0538	isocitrate dehydrogenase activity
DTO10_05040	COG0372	Belongs to the citrate synthase family
DTO10_05045	COG2707	UPF0756 membrane protein
DTO10_05050	COG0628	permease
DTO10_05055	COG2224	Isocitrate lyase
DTO10_05060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DTO10_05075	COG0205	6-phosphofructokinase activity
DTO10_05080	COG0825	malonyl-CoA metabolic process
DTO10_05085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DTO10_05090	COG2186	Transcriptional regulator
DTO10_05095	COG0281	malic enzyme
DTO10_05100	COG0587	DNA-directed DNA polymerase activity
DTO10_05115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DTO10_05125	COG4109	DRTGG domain
DTO10_05135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DTO10_05140	COG0006	proline dipeptidase activity
DTO10_05145	COG0589	response to stress
DTO10_05150	COG0165	Argininosuccinate lyase
DTO10_05155	COG0137	argininosuccinate synthase activity
DTO10_05165	COG0521	Mo-molybdopterin cofactor biosynthetic process
DTO10_05170	COG2217	Heavy metal translocating P-type atpase
DTO10_05175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DTO10_05180	COG0827	DNA restriction-modification system
DTO10_05185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DTO10_05190	COG3874	Sporulation protein YtfJ
DTO10_05200	COG1714	RDD family
DTO10_05205	COG0616	signal peptide processing
DTO10_05210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DTO10_05215	COG0084	hydrolase, TatD family'
DTO10_05220	COG1116	anion transmembrane transporter activity
DTO10_05225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_05235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_05245	COG2962	Rard protein
DTO10_05250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_05255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_05265	COG0301	tRNA thio-modification
DTO10_05270	COG1104	cysteine desulfurase activity
DTO10_05275	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DTO10_05280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DTO10_05290	COG1956	GAF domain-containing protein
DTO10_05295	COG2199	diguanylate cyclase activity
DTO10_05295	COG2203	Gaf domain
DTO10_05300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DTO10_05305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DTO10_05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_05320	COG0454	-acetyltransferase
DTO10_05325	COG0517	IMP dehydrogenase activity
DTO10_05330	COG0123	including yeast histone deacetylase and acetoin utilization protein
DTO10_05335	COG1609	Transcriptional regulator
DTO10_05340	COG1605	Chorismate mutase
DTO10_05340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DTO10_05350	COG3118	belongs to the thioredoxin family
DTO10_05355	COG4980	gas vesicle protein
DTO10_05365	COG2309	aminopeptidase activity
DTO10_05375	COG1674	ftsk spoiiie
DTO10_05380	COG1473	amidohydrolase
DTO10_05385	COG4848	Belongs to the UPF0354 family
DTO10_05390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_05405	COG2207	Transcriptional regulator
DTO10_05405	COG3708	Transcriptional regulator
DTO10_05410	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DTO10_05415	COG1363	Peptidase, m42
DTO10_05425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_05430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DTO10_05440	COG0510	thiamine kinase activity
DTO10_05445	COG1597	lipid kinase activity
DTO10_05465	COG1914	H( )-stimulated, divalent metal cation uptake system
DTO10_05470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_05475	COG1122	ATPase activity
DTO10_05480	COG1122	ATPase activity
DTO10_05485	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_05490	COG0183	Belongs to the thiolase family
DTO10_05495	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_05500	COG1268	BioY protein
DTO10_05510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_05515	COG0534	Mate efflux family protein
DTO10_05525	COG0586	Pfam SNARE associated Golgi protein
DTO10_05560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DTO10_05560	COG1587	Uroporphyrinogen-III synthase
DTO10_05565	COG1587	Uroporphyrinogen-III synthase
DTO10_05570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DTO10_05580	COG0697	spore germination
DTO10_05585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DTO10_05590	COG0124	histidyl-tRNA synthetase
DTO10_05600	COG0701	Predicted permease
DTO10_05630	COG2824	Alkylphosphonate utilization operon protein PhnA
DTO10_05635	COG0745	RESPONSE REGULATOR receiver
DTO10_05640	COG0642	Histidine kinase
DTO10_05645	COG1136	(ABC) transporter
DTO10_05650	COG0577	efflux transmembrane transporter activity
DTO10_05675	COG1349	DNA-binding transcription factor activity
DTO10_05680	COG1187	pseudouridine synthase activity
DTO10_05685	COG2244	polysaccharide biosynthetic process
DTO10_05690	COG2081	HI0933 family
DTO10_05710	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_05720	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_05725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_05730	COG1902	pentaerythritol trinitrate reductase activity
DTO10_05740	COG0656	L-ascorbic acid biosynthetic process
DTO10_05745	COG2814	Major facilitator Superfamily
DTO10_05750	COG1733	regulation of RNA biosynthetic process
DTO10_05765	COG1309	transcriptional regulator
DTO10_05780	COG1647	Serine aminopeptidase, S33
DTO10_05785	COG1695	Transcriptional regulator
DTO10_05805	COG1309	transcriptional regulator
DTO10_05820	COG0720	synthase
DTO10_05830	COG0840	transmembrane signaling receptor activity
DTO10_05860	COG4195	phage-related replication protein
DTO10_05865	COG0791	NLP P60 protein
DTO10_05870	COG1595	DNA-templated transcription, initiation
DTO10_05880	COG1733	regulation of RNA biosynthetic process
DTO10_05890	COG2318	DinB family
DTO10_05900	COG0456	acetyltransferase
DTO10_05905	COG2002	toxin-antitoxin pair type II binding
DTO10_05910	COG0697	spore germination
DTO10_05915	COG2076	Multidrug Resistance protein
DTO10_05920	COG2076	Multidrug Resistance protein
DTO10_05930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_05940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_05950	COG0697	spore germination
DTO10_05955	COG0586	Pfam SNARE associated Golgi protein
DTO10_05960	COG0671	phosphoesterase, PA-phosphatase related
DTO10_05965	COG2226	methyltransferase
DTO10_05980	COG0583	DNA-binding transcription factor activity
DTO10_05985	COG2807	transmembrane transport
DTO10_05995	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_06005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_06010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DTO10_06015	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_06020	COG3829	transcription factor binding
DTO10_06030	COG2514	catechol 2,3-dioxygenase activity
DTO10_06035	COG2259	Doxx family
DTO10_06040	COG1668	transmembrane transport
DTO10_06045	COG4152	abc transporter atp-binding protein
DTO10_06055	COG0534	Mate efflux family protein
DTO10_06060	COG4608	Belongs to the ABC transporter superfamily
DTO10_06065	COG0444	Belongs to the ABC transporter superfamily
DTO10_06090	COG1126	abc transporter atp-binding protein
DTO10_06105	COG1309	transcriptional regulator
DTO10_06110	COG0246	Mannitol dehydrogenase
DTO10_06115	COG3711	transcriptional antiterminator
DTO10_06120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_06120	COG2213	PTS system mannitol-specific
DTO10_06125	COG2851	Citrate transporter
DTO10_06130	COG4565	transcriptional regulatory protein
DTO10_06135	COG3290	protein histidine kinase activity
DTO10_06150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DTO10_06165	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_06170	COG2169	Transcriptional regulator
DTO10_06175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DTO10_06185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DTO10_06205	COG0346	lactoylglutathione lyase activity
DTO10_06220	COG0697	spore germination
DTO10_06245	COG1823	symporter activity
DTO10_06255	COG1113	amino acid transport
DTO10_06265	COG0785	Cytochrome C biogenesis protein
DTO10_06285	COG2197	response regulator
DTO10_06290	COG4585	Histidine kinase
DTO10_06310	COG1309	transcriptional regulator
DTO10_06315	COG3844	kynureninase activity
DTO10_06320	COG1113	amino acid transport
DTO10_06325	COG3483	tryptophan 2,3-dioxygenase activity
DTO10_06330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DTO10_06335	COG1280	lysine exporter protein (LysE YggA)
DTO10_06350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_06370	COG0583	DNA-binding transcription factor activity
DTO10_06375	COG1511	domain protein
DTO10_06380	COG2814	Major facilitator Superfamily
DTO10_06385	COG1309	transcriptional regulator
DTO10_06405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_06410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DTO10_06420	COG0833	amino acid
DTO10_06430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_06435	COG0183	Belongs to the thiolase family
DTO10_06440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_06445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_06450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_06455	COG1141	Ferredoxin
DTO10_06470	COG1509	lysine 2,3-aminomutase activity
DTO10_06475	COG3829	transcription factor binding
DTO10_06495	COG3011	Protein conserved in bacteria
DTO10_06540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DTO10_06565	COG4989	oxidoreductase activity
DTO10_06570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_06660	COG5444	nuclease activity
DTO10_06670	COG0477	Major facilitator Superfamily
DTO10_06705	COG3973	AAA domain
DTO10_06720	COG0579	oxidoreductase
DTO10_06725	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_06735	COG2610	gluconate transmembrane transporter activity
DTO10_06740	COG0583	DNA-binding transcription factor activity
DTO10_06780	COG0346	lactoylglutathione lyase activity
DTO10_06785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_06790	COG2814	Major facilitator Superfamily
DTO10_06795	COG4154	Belongs to the RbsD FucU family
DTO10_06800	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_06805	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_06810	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_06845	COG4319	ketosteroid isomerase
DTO10_06870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_06875	COG2318	DinB family
DTO10_06890	COG1114	Component of the transport system for branched-chain amino acids
DTO10_06895	COG1113	amino acid transport
DTO10_06900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DTO10_06905	COG0156	8-amino-7-oxononanoate synthase activity
DTO10_06915	COG1280	lysine exporter protein (LysE YggA)
DTO10_06930	COG1694	Mazg nucleotide pyrophosphohydrolase
DTO10_06945	COG1396	sequence-specific DNA binding
DTO10_06985	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DTO10_06990	COG0251	oxidation-reduction process
DTO10_06995	COG0833	amino acid
DTO10_07005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_07015	COG0446	pyridine nucleotide-disulphide oxidoreductase
DTO10_07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_07040	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DTO10_07045	COG0640	Transcriptional regulator
DTO10_07050	COG2801	Transposase and inactivated derivatives
DTO10_07060	COG2323	membrane
DTO10_07070	COG2261	transglycosylase associated protein
DTO10_07080	COG3848	Pyruvate phosphate dikinase
DTO10_07080	COG0574	Belongs to the PEP-utilizing enzyme family
DTO10_07135	COG1595	DNA-templated transcription, initiation
DTO10_07165	COG1846	Transcriptional regulator
DTO10_07170	COG0778	Nitroreductase
DTO10_07195	COG0531	amino acid
DTO10_07200	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_07220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_07225	COG2602	Beta-lactamase
DTO10_07230	COG2197	response regulator
DTO10_07235	COG3239	Fatty acid desaturase
DTO10_07240	COG1027	Aspartate ammonia-lyase
DTO10_07245	COG0252	asparaginase activity
DTO10_07250	COG1396	sequence-specific DNA binding
DTO10_07255	COG1120	ATPase activity
DTO10_07260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_07265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_07270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DTO10_07275	COG0561	phosphatase activity
DTO10_07305	COG1335	isochorismatase
DTO10_07325	COG0477	Major facilitator Superfamily
DTO10_07330	COG1309	transcriptional regulator
DTO10_07350	COG1966	Carbon starvation protein
DTO10_07355	COG3279	Response regulator of the LytR AlgR family
DTO10_07360	COG3275	phosphorelay sensor kinase activity
DTO10_07365	COG0583	DNA-binding transcription factor activity
DTO10_07370	COG0697	spore germination
DTO10_07380	COG1193	negative regulation of DNA recombination
DTO10_07385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DTO10_07390	COG3842	ATPase activity
DTO10_07395	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_07400	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_07435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_07465	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_07470	COG2197	response regulator
DTO10_07475	COG2233	PERMEase
DTO10_07485	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_07490	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_07495	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_07500	COG0747	negative chemotaxis
DTO10_07505	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_07510	COG0402	S-adenosylhomocysteine deaminase activity
DTO10_07515	COG0747	negative chemotaxis
DTO10_07530	COG0444	Belongs to the ABC transporter superfamily
DTO10_07535	COG4608	Belongs to the ABC transporter superfamily
DTO10_07540	COG3275	phosphorelay sensor kinase activity
DTO10_07545	COG2207	Transcriptional regulator
DTO10_07545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_07555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DTO10_07565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DTO10_07615	COG0778	Nitroreductase
DTO10_07665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_07670	COG0697	spore germination
DTO10_07680	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_07695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DTO10_07700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DTO10_07710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_07720	COG1609	Transcriptional regulator
DTO10_07725	COG2318	DinB family
DTO10_07735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_07735	COG0456	acetyltransferase
DTO10_07760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_07765	COG1131	(ABC) transporter
DTO10_07790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_07795	COG3584	3D domain protein
DTO10_07795	COG3583	domain protein
DTO10_07825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_07830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_07840	COG0384	phenazine biosynthesis protein PhzF
DTO10_07855	COG1595	DNA-templated transcription, initiation
DTO10_07865	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_07895	COG1231	oxidoreductase activity
DTO10_07905	COG0697	spore germination
DTO10_07910	COG0531	amino acid
DTO10_07925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DTO10_07930	COG0569	domain protein
DTO10_07940	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_07945	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_07955	COG2226	methyltransferase
DTO10_07975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DTO10_07980	COG0463	Glycosyl transferase, family 2
DTO10_07980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_07985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DTO10_07990	COG2910	NAD(P)H-binding
DTO10_07995	COG1959	2 iron, 2 sulfur cluster binding
DTO10_08000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DTO10_08005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DTO10_08010	COG1959	2 iron, 2 sulfur cluster binding
DTO10_08015	COG4193	domain, Protein
DTO10_08020	COG2112	serine threonine protein kinase
DTO10_08030	COG3832	glyoxalase III activity
DTO10_08035	COG0640	Transcriptional regulator
DTO10_08040	COG1511	domain protein
DTO10_08045	COG1959	2 iron, 2 sulfur cluster binding
DTO10_08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_08065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DTO10_08080	COG0346	lactoylglutathione lyase activity
DTO10_08100	COG1846	Transcriptional regulator
DTO10_08105	COG2814	Major facilitator Superfamily
DTO10_08120	COG1131	(ABC) transporter
DTO10_08140	COG1609	Transcriptional regulator
DTO10_08145	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_08145	COG0456	acetyltransferase
DTO10_08165	COG0586	Pfam SNARE associated Golgi protein
DTO10_08170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DTO10_08180	COG0726	polysaccharide deacetylase
DTO10_08185	COG3850	Histidine kinase
DTO10_08185	COG5002	protein histidine kinase activity
DTO10_08190	COG0745	RESPONSE REGULATOR receiver
DTO10_08205	COG0725	ABC transporter, periplasmic molybdate-binding protein
DTO10_08210	COG1910	domain protein
DTO10_08235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DTO10_08240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_08265	COG3104	oligopeptide transport
DTO10_08280	COG1595	DNA-templated transcription, initiation
DTO10_08285	COG0726	polysaccharide deacetylase
DTO10_08305	COG4302	ethanolamine ammonia-lyase activity
DTO10_08310	COG4303	Ethanolamine ammonia lyase large subunit
DTO10_08355	COG4548	von Willebrand factor, type A
DTO10_08360	COG0714	Associated with various cellular activities
DTO10_08365	COG1114	Component of the transport system for branched-chain amino acids
DTO10_08370	COG0110	maltose O-acetyltransferase activity
DTO10_08375	COG0702	epimerase
DTO10_08380	COG5566	PFAM Mor transcription activator
DTO10_08390	COG0493	'glutamate synthase
DTO10_08395	COG0067	glutamate synthase
DTO10_08395	COG0070	glutamate synthase
DTO10_08395	COG0069	glutamate synthase activity
DTO10_08400	COG0583	DNA-binding transcription factor activity
DTO10_08405	COG5577	PFAM Coat F domain
DTO10_08415	COG1404	Belongs to the peptidase S8 family
DTO10_08420	COG0495	leucyl-tRNA aminoacylation
DTO10_08435	COG1242	4 iron, 4 sulfur cluster binding
DTO10_08440	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DTO10_08450	COG2267	carboxylic ester hydrolase activity
DTO10_08455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DTO10_08495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DTO10_08500	COG0840	transmembrane signaling receptor activity
DTO10_08530	COG1683	Conserved Protein
DTO10_08540	COG1506	peptidase
DTO10_08545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_08550	COG1116	anion transmembrane transporter activity
DTO10_08555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_08575	COG0783	Belongs to the Dps family
DTO10_08585	COG1854	S-ribosylhomocysteine lyase activity
DTO10_08590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DTO10_08595	COG3443	Belongs to the bacterial solute-binding protein 9 family
DTO10_08595	COG0803	Belongs to the bacterial solute-binding protein 9 family
DTO10_08600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DTO10_08605	COG3290	protein histidine kinase activity
DTO10_08610	COG4565	transcriptional regulatory protein
DTO10_08615	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_08620	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_08625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DTO10_08635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DTO10_08640	COG1169	isochorismate synthase
DTO10_08645	COG1575	Belongs to the MenA family. Type 1 subfamily
DTO10_08650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DTO10_08775	COG0697	spore germination
DTO10_08780	COG1285	pathogenesis
DTO10_08795	COG0506	proline dehydrogenase activity
DTO10_08800	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_08805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_08810	COG2508	Transcriptional regulator
DTO10_08820	COG1309	transcriptional regulator
DTO10_08825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_08840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DTO10_08865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DTO10_08870	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DTO10_08880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DTO10_08900	COG0833	amino acid
DTO10_08920	COG1472	Belongs to the glycosyl hydrolase 3 family
DTO10_08935	COG1378	Sugar-specific transcriptional regulator TrmB
DTO10_08950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DTO10_08955	COG0604	alcohol dehydrogenase
DTO10_08960	COG4191	Histidine kinase
DTO10_08965	COG3773	Cell wall hydrolase
DTO10_08970	COG3906	Belongs to the UPF0473 family
DTO10_08975	COG0346	lactoylglutathione lyase activity
DTO10_08990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_08995	COG0523	cobalamin synthesis protein
DTO10_09000	COG0322	excinuclease ABC activity
DTO10_09015	COG1785	Belongs to the alkaline phosphatase family
DTO10_09025	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DTO10_09030	COG0196	riboflavin kinase activity
DTO10_09040	COG0753	catalase activity
DTO10_09050	COG1950	PFAM Membrane protein of
DTO10_09055	COG0640	Transcriptional regulator
DTO10_09060	COG2814	Major facilitator Superfamily
DTO10_09065	COG2356	endonuclease I
DTO10_09070	COG1113	amino acid transport
DTO10_09080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_09095	COG0697	spore germination
DTO10_09100	COG0737	Belongs to the 5'-nucleotidase family
DTO10_09105	COG2318	DinB family
DTO10_09110	COG0456	acetyltransferase
DTO10_09120	COG1191	sigma factor activity
DTO10_09150	COG2814	Major facilitator Superfamily
DTO10_09155	COG0531	amino acid
DTO10_09160	COG1968	undecaprenyl-diphosphatase activity
DTO10_09165	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_09175	COG1388	LysM domain
DTO10_09175	COG3858	chitin binding
DTO10_09185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DTO10_09200	COG1979	alcohol dehydrogenase
DTO10_09205	COG2155	Conserved Protein
DTO10_09210	COG1098	S1 RNA binding domain
DTO10_09220	COG0436	Aminotransferase
DTO10_09225	COG1522	sequence-specific DNA binding
DTO10_09230	COG2267	carboxylic ester hydrolase activity
DTO10_09240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_09245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DTO10_09255	COG0456	acetyltransferase
DTO10_09265	COG1309	transcriptional regulator
DTO10_09275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DTO10_09285	COG5018	Exonuclease
DTO10_09290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_09295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_09300	COG2111	Na H antiporter
DTO10_09300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DTO10_09305	COG2111	Na H antiporter
DTO10_09310	COG1006	Multisubunit Na H antiporter MnhC subunit
DTO10_09315	COG0651	ATP synthesis coupled electron transport
DTO10_09320	COG1863	multisubunit Na H antiporter MnhE subunit
DTO10_09325	COG2212	antiporter activity
DTO10_09340	COG2050	protein possibly involved in aromatic compounds catabolism
DTO10_09355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DTO10_09355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DTO10_09360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_09360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_09370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DTO10_09375	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DTO10_09385	COG3584	3D domain protein
DTO10_09400	COG1252	NADH dehydrogenase
DTO10_09415	COG0316	Belongs to the HesB IscA family
DTO10_09420	COG4844	belongs to the
DTO10_09425	COG1252	NADH dehydrogenase
DTO10_09430	COG4837	Protein of unknown function (DUF1462)
DTO10_09435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DTO10_09440	COG0083	homoserine kinase activity
DTO10_09445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DTO10_09450	COG0460	homoserine dehydrogenase
DTO10_09460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_09465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DTO10_09470	COG0647	UMP catabolic process
DTO10_09475	COG2445	Protein of unknown function DUF86
DTO10_09490	COG4470	Protein conserved in bacteria
DTO10_09500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DTO10_09505	COG0739	heme binding
DTO10_09520	COG3377	Domain of unknown function (DUF1805)
DTO10_09525	COG0737	Belongs to the 5'-nucleotidase family
DTO10_09530	COG0730	response to heat
DTO10_09535	COG1801	Protein of unknown function DUF72
DTO10_09540	COG0719	Fe-S assembly protein
DTO10_09545	COG0822	iron-sulfur transferase activity
DTO10_09550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DTO10_09555	COG0719	Fe-S assembly protein
DTO10_09560	COG0396	ATPase activity
DTO10_09575	COG1464	Belongs to the NlpA lipoprotein family
DTO10_09580	COG2011	ABC-type metal ion transport system permease component
DTO10_09585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_09595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_09600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DTO10_09605	COG0509	glycine decarboxylation via glycine cleavage system
DTO10_09610	COG1393	Belongs to the ArsC family
DTO10_09615	COG1960	acyl-CoA dehydrogenase activity
DTO10_09620	COG0183	Belongs to the thiolase family
DTO10_09625	COG1024	Enoyl-CoA hydratase
DTO10_09625	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_09635	COG0506	proline dehydrogenase activity
DTO10_09645	COG5577	PFAM Coat F domain
DTO10_09650	COG0772	Belongs to the SEDS family
DTO10_09655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_09660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DTO10_09660	COG1321	iron dependent repressor
DTO10_09665	COG1121	(ABC) transporter
DTO10_09670	COG0803	Belongs to the bacterial solute-binding protein 9 family
DTO10_09680	COG1609	Transcriptional regulator
DTO10_09685	COG0833	amino acid
DTO10_09705	COG2076	Multidrug Resistance protein
DTO10_09730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_09735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DTO10_09740	COG1368	sulfuric ester hydrolase activity
DTO10_09745	COG4607	ABC-type enterochelin transport system periplasmic component
DTO10_09750	COG4604	ABC transporter, ATP-binding protein
DTO10_09755	COG4605	iron ion homeostasis
DTO10_09760	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_09765	COG4844	belongs to the
DTO10_09775	COG1657	PFAM Prenyltransferase squalene oxidase
DTO10_09790	COG5002	protein histidine kinase activity
DTO10_09790	COG3850	Histidine kinase
DTO10_09795	COG0745	RESPONSE REGULATOR receiver
DTO10_09800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_09805	COG2197	response regulator
DTO10_09810	COG4585	Histidine kinase
DTO10_09815	COG3239	Fatty acid desaturase
DTO10_09825	COG3290	protein histidine kinase activity
DTO10_09850	COG0583	DNA-binding transcription factor activity
DTO10_09855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DTO10_09860	COG5609	conserved protein (DUF2294)
DTO10_09865	COG3383	formate dehydrogenase (NAD+) activity
DTO10_09870	COG2427	Protein of unknown function (DUF1641)
DTO10_09875	COG0489	protein tyrosine kinase activity
DTO10_09885	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DTO10_09895	COG2814	Major facilitator Superfamily
DTO10_09905	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DTO10_09910	COG0557	exoribonuclease II activity
DTO10_09915	COG1647	Serine aminopeptidase, S33
DTO10_09920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DTO10_09930	COG1876	peptidase activity
DTO10_09950	COG0126	phosphoglycerate kinase activity
DTO10_09955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DTO10_09970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DTO10_09980	COG0740	serine-type endopeptidase activity
DTO10_09985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DTO10_09995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DTO10_10000	COG1660	Displays ATPase and GTPase activities
DTO10_10005	COG1051	belongs to the nudix hydrolase family
DTO10_10010	COG0492	ferredoxin-NADP+ reductase activity
DTO10_10015	COG0457	Tetratricopeptide repeat
DTO10_10020	COG0140	phosphoribosyl-ATP diphosphatase activity
DTO10_10020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DTO10_10025	COG0107	imidazoleglycerol-phosphate synthase activity
DTO10_10030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DTO10_10035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DTO10_10040	COG0131	Imidazoleglycerol-phosphate dehydratase
DTO10_10045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DTO10_10050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DTO10_10055	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DTO10_10065	COG3764	Sortase (surface protein transpeptidase)
DTO10_10070	COG0110	maltose O-acetyltransferase activity
DTO10_10075	COG0546	phosphoglycolate phosphatase activity
DTO10_10080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DTO10_10100	COG3595	metallopeptidase activity
DTO10_10105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DTO10_10110	COG0556	nucleotide-excision repair
DTO10_10115	COG4897	Protein conserved in bacteria
DTO10_10120	COG0753	catalase activity
DTO10_10130	COG2353	YceI-like domain
DTO10_10135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_10140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_10145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_10150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_10155	COG0793	Belongs to the peptidase S41A family
DTO10_10155	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_10160	COG0791	NLP P60 protein
DTO10_10160	COG3883	PFAM NLP P60 protein
DTO10_10165	COG2177	Part of the ABC transporter FtsEX involved in
DTO10_10170	COG2884	Cell division ATP-binding protein ftsE
DTO10_10180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_10190	COG0653	protein targeting
DTO10_10195	COG1396	sequence-specific DNA binding
DTO10_10210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DTO10_10220	COG1516	flagellar protein fliS
DTO10_10225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DTO10_10230	COG1334	flagellar protein FlaG
DTO10_10235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DTO10_10240	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DTO10_10245	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DTO10_10255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DTO10_10260	COG4786	Flagellar basal body rod
DTO10_10260	COG1256	bacterial-type flagellum assembly
DTO10_10285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DTO10_10290	COG1307	EDD domain protein, DegV family
DTO10_10295	COG2197	response regulator
DTO10_10300	COG4585	Histidine kinase
DTO10_10305	COG1739	Uncharacterized protein family UPF0029
DTO10_10310	COG1316	TRANSCRIPTIONal
DTO10_10315	COG1215	transferase activity, transferring glycosyl groups
DTO10_10315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_10320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DTO10_10325	COG0438	transferase activity, transferring glycosyl groups
DTO10_10330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DTO10_10340	COG0728	peptidoglycan biosynthetic process
DTO10_10345	COG0438	transferase activity, transferring glycosyl groups
DTO10_10355	COG1682	transport, permease protein
DTO10_10360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_10365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_10370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DTO10_10375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DTO10_10385	COG0791	NLP P60 protein
DTO10_10385	COG1388	LysM domain
DTO10_10400	COG1368	sulfuric ester hydrolase activity
DTO10_10410	COG0653	protein targeting
DTO10_10415	COG1785	Belongs to the alkaline phosphatase family
DTO10_10420	COG2385	sporulation resulting in formation of a cellular spore
DTO10_10420	COG2247	cell wall binding repeat
DTO10_10425	COG2356	endonuclease I
DTO10_10430	COG0737	Belongs to the 5'-nucleotidase family
DTO10_10435	COG0768	penicillin binding
DTO10_10465	COG4715	Zinc finger, swim domain protein
DTO10_10470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DTO10_10480	COG1279	arginine transmembrane transporter activity
DTO10_10485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_10510	COG0747	negative chemotaxis
DTO10_10515	COG4608	Belongs to the ABC transporter superfamily
DTO10_10520	COG0444	Belongs to the ABC transporter superfamily
DTO10_10525	COG0629	single-stranded DNA binding
DTO10_10550	COG4786	Flagellar basal body rod
DTO10_10555	COG4786	Flagellar basal body rod
DTO10_10560	COG1077	Cell shape determining protein MreB Mrl
DTO10_10565	COG1609	Transcriptional regulator
DTO10_10570	COG0739	heme binding
DTO10_10580	COG2385	sporulation resulting in formation of a cellular spore
DTO10_10595	COG4836	Membrane
DTO10_10600	COG1007	ATP synthesis coupled electron transport
DTO10_10605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_10610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DTO10_10615	COG0713	ATP synthesis coupled electron transport
DTO10_10620	COG0839	Belongs to the complex I subunit 6 family
DTO10_10625	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_10640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_10645	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_10650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DTO10_10660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DTO10_10675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DTO10_10685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DTO10_10690	COG0356	it plays a direct role in the translocation of protons across the membrane
DTO10_10705	COG1404	Belongs to the peptidase S8 family
DTO10_10710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DTO10_10715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DTO10_10730	COG0698	ribose 5-phosphate isomerase
DTO10_10735	COG0840	transmembrane signaling receptor activity
DTO10_10745	COG1971	Probably functions as a manganese efflux pump
DTO10_10750	COG0009	L-threonylcarbamoyladenylate synthase
DTO10_10760	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_10765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DTO10_10780	COG0832	Belongs to the urease beta subunit family
DTO10_10785	COG0804	urea catabolic process
DTO10_10790	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DTO10_10795	COG0830	nickel cation binding
DTO10_10800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DTO10_10805	COG0829	nickel cation binding
DTO10_10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_10830	COG0601	transmembrane transport
DTO10_10840	COG1435	thymidine kinase activity
DTO10_10850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DTO10_10855	COG1494	fructose-1,6-bisphosphatase
DTO10_10865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DTO10_10875	COG2204	response regulator
DTO10_10880	COG4821	SIS domain
DTO10_10885	COG0504	CTP synthase activity
DTO10_10890	COG3343	RNA polymerase activity
DTO10_10895	COG1703	isobutyryl-CoA mutase activity
DTO10_10895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_10895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DTO10_10905	COG1960	acyl-CoA dehydrogenase activity
DTO10_10910	COG1960	acyl-CoA dehydrogenase activity
DTO10_10915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_10920	COG0183	Belongs to the thiolase family
DTO10_10925	COG2181	nitrate reductase activity
DTO10_10925	COG0247	lactate metabolic process
DTO10_10930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_10940	COG0018	arginyl-trna synthetase
DTO10_10950	COG0010	Belongs to the arginase family
DTO10_10955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DTO10_10960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_10970	COG1994	Peptidase M50
DTO10_10980	COG3465	dGTPase activity
DTO10_10985	COG1078	dGTPase activity
DTO10_10990	COG4844	belongs to the
DTO10_11000	COG0095	Lipoate-protein ligase
DTO10_11005	COG0280	phosphate acetyltransferase
DTO10_11020	COG2363	Small membrane protein
DTO10_11035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DTO10_11050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DTO10_11055	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DTO10_11060	COG0314	molybdopterin synthase activity
DTO10_11065	COG0746	molybdenum cofactor guanylyltransferase activity
DTO10_11070	COG0351	phosphomethylpyrimidine kinase
DTO10_11075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DTO10_11085	COG2814	Major facilitator Superfamily
DTO10_11090	COG1846	Transcriptional regulator
DTO10_11100	COG0561	phosphatase activity
DTO10_11110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DTO10_11135	COG2096	Adenosyltransferase
DTO10_11145	COG0588	phosphoglycerate mutase activity
DTO10_11150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DTO10_11160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_11165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DTO10_11170	COG1120	ATPase activity
DTO10_11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_11185	COG0726	polysaccharide deacetylase
DTO10_11190	COG1120	ATPase activity
DTO10_11220	COG0778	Nitroreductase
DTO10_11225	COG0551	DNA topoisomerase type I activity
DTO10_11225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DTO10_11230	COG0488	(ABC) transporter
DTO10_11255	COG2252	PERMEase
DTO10_11280	COG0723	plastoquinol--plastocyanin reductase activity
DTO10_11280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_11285	COG4895	conserved protein (DUF2196)
DTO10_11295	COG0788	formyltetrahydrofolate deformylase activity
DTO10_11310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_11325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DTO10_11335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_11335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DTO10_11340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_11350	COG5002	protein histidine kinase activity
DTO10_11355	COG0745	RESPONSE REGULATOR receiver
DTO10_11360	COG0577	efflux transmembrane transporter activity
DTO10_11365	COG1136	(ABC) transporter
DTO10_11375	COG3162	membrane
DTO10_11380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_11395	COG2267	carboxylic ester hydrolase activity
DTO10_11400	COG1301	dicarboxylic acid transport
DTO10_11410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DTO10_11420	COG0583	DNA-binding transcription factor activity
DTO10_11425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_11430	COG1879	ABC-type sugar transport system periplasmic component
DTO10_11435	COG1172	Belongs to the binding-protein-dependent transport system permease family
DTO10_11440	COG1129	ABC transporter
DTO10_11445	COG1869	D-ribose catabolic process
DTO10_11450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_11455	COG1609	Transcriptional regulator
DTO10_11475	COG4264	IucA IucC family
DTO10_11480	COG0076	glutamate decarboxylase activity
DTO10_11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
DTO10_11520	COG0583	DNA-binding transcription factor activity
DTO10_11535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DTO10_11540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DTO10_11550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_11555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DTO10_11560	COG4853	Protein conserved in bacteria
DTO10_11570	COG5002	protein histidine kinase activity
DTO10_11575	COG0745	RESPONSE REGULATOR receiver
DTO10_11610	COG0305	Participates in initiation and elongation during chromosome replication
DTO10_11615	COG0359	binds to the 23S rRNA
DTO10_11620	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DTO10_11630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DTO10_11635	COG0629	single-stranded DNA binding
DTO10_11640	COG0360	Binds together with S18 to 16S ribosomal RNA
DTO10_11645	COG0012	GTP binding
DTO10_11650	COG4481	Protein conserved in bacteria
DTO10_11655	COG0668	transmembrane transport
DTO10_11665	COG1811	Na channel or pump
DTO10_11670	COG1475	DNA binding
DTO10_11675	COG1192	Involved in chromosome partitioning
DTO10_11680	COG1475	DNA binding
DTO10_11685	COG0357	Ribosomal RNA small subunit methyltransferase G
DTO10_11690	COG0445	tRNA wobble uridine modification
DTO10_11700	COG1847	R3H domain protein
DTO10_11705	COG0706	membrane insertase activity
DTO10_11710	COG0594	ribonuclease P activity
DTO10_11720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DTO10_11725	COG0592	DNA-directed DNA polymerase activity
DTO10_11730	COG2501	S4 domain
DTO10_11735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DTO10_11745	COG0187	DNA topoisomerase II activity
DTO10_11750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DTO10_11755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DTO10_11790	COG0517	IMP dehydrogenase activity
DTO10_11790	COG0516	GMP reductase activity
DTO10_11810	COG1428	Deoxynucleoside kinase
DTO10_11815	COG1428	Deoxynucleoside kinase
DTO10_11820	COG1335	isochorismatase
DTO10_11825	COG0590	tRNA wobble adenosine to inosine editing
DTO10_11835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DTO10_11840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DTO10_11845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DTO10_11890	COG1982	Orn Lys Arg decarboxylase major
DTO10_11895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DTO10_11900	COG3870	Protein conserved in bacteria
DTO10_11905	COG1728	Protein conserved in bacteria
DTO10_11910	COG0470	DNA polymerase III
DTO10_11915	COG1774	PSP1 C-terminal conserved region
DTO10_11920	COG4467	Involved in initiation control of chromosome replication
DTO10_11925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DTO10_11935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DTO10_11940	COG2002	toxin-antitoxin pair type II binding
DTO10_11950	COG0084	hydrolase, TatD family'
DTO10_11955	COG3584	3D domain protein
DTO10_11955	COG3583	domain protein
DTO10_11975	COG4466	Protein conserved in bacteria
DTO10_11990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DTO10_11995	COG0251	oxidation-reduction process
DTO10_12000	COG2088	sporulation resulting in formation of a cellular spore
DTO10_12005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DTO10_12010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DTO10_12015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_12020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_12025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_12030	COG1116	anion transmembrane transporter activity
DTO10_12035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DTO10_12050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DTO10_12055	COG2002	toxin-antitoxin pair type II binding
DTO10_12060	COG2244	polysaccharide biosynthetic process
DTO10_12065	COG3956	TIGRFAM MazG family protein
DTO10_12070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DTO10_12085	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DTO10_12090	COG1098	S1 RNA binding domain
DTO10_12105	COG2208	phosphoserine phosphatase activity
DTO10_12110	COG2304	oxidoreductase activity
DTO10_12115	COG0515	serine threonine protein kinase
DTO10_12120	COG0037	tRNA processing
DTO10_12130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DTO10_12135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DTO10_12140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DTO10_12145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_12150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_12155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DTO10_12160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DTO10_12165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DTO10_12170	COG1396	sequence-specific DNA binding
DTO10_12175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DTO10_12180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DTO10_12205	COG3880	PFAM UvrB UvrC protein
DTO10_12210	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DTO10_12215	COG0542	response to heat
DTO10_12220	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DTO10_12230	COG4956	integral membrane protein (PIN domain superfamily)
DTO10_12240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DTO10_12245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DTO10_12250	COG1045	serine acetyltransferase
DTO10_12255	COG0215	cysteine-tRNA ligase activity
DTO10_12265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DTO10_12270	COG3688	RNA-binding protein containing a PIN domain
DTO10_12280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DTO10_12285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DTO10_12290	COG0250	Participates in transcription elongation, termination and antitermination
DTO10_12300	COG0081	regulation of translation
DTO10_12315	COG2813	Specifically methylates the guanine in position
DTO10_12320	COG0085	RNA polymerase activity
DTO10_12325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DTO10_12330	COG1358	cellular component organization or biogenesis
DTO10_12335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DTO10_12340	COG0049	tRNA binding
DTO10_12345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DTO10_12355	COG0051	transcription antitermination factor activity, RNA binding
DTO10_12360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DTO10_12365	COG0088	Forms part of the polypeptide exit tunnel
DTO10_12375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DTO10_12380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DTO10_12385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DTO10_12390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DTO10_12395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DTO10_12400	COG0255	Belongs to the universal ribosomal protein uL29 family
DTO10_12405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DTO10_12410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DTO10_12415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DTO10_12425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DTO10_12430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DTO10_12435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DTO10_12440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DTO10_12445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DTO10_12450	COG1841	ribosomal large subunit assembly
DTO10_12460	COG0201	protein transport
DTO10_12470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DTO10_12475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DTO10_12480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DTO10_12485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DTO10_12490	COG0202	RNA polymerase activity
DTO10_12495	COG0203	ribosomal protein L17
DTO10_12500	COG1122	ATPase activity
DTO10_12505	COG1122	ATPase activity
DTO10_12510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DTO10_12525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DTO10_12535	COG0383	alpha-mannosidase activity
DTO10_12550	COG5578	integral membrane protein
DTO10_12560	COG2972	Histidine kinase
DTO10_12565	COG2207	Transcriptional regulator
DTO10_12565	COG4753	response regulator
DTO10_12570	COG4209	transmembrane transport
DTO10_12575	COG0395	ABC-type sugar transport system, permease component
DTO10_12585	COG2723	6-phospho-beta-galactosidase activity
DTO10_12590	COG1940	carbohydrate kinase activity
DTO10_12595	COG1940	carbohydrate kinase activity
DTO10_12600	COG1482	cell wall glycoprotein biosynthetic process
DTO10_12615	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_12620	COG0489	protein tyrosine kinase activity
DTO10_12630	COG2194	sulfuric ester hydrolase activity
DTO10_12635	COG0726	polysaccharide deacetylase
DTO10_12715	COG1595	DNA-templated transcription, initiation
DTO10_12720	COG5662	AntiSigma factor
DTO10_12725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DTO10_12730	COG4856	YbbR-like protein
DTO10_12735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DTO10_12740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DTO10_12745	COG5646	InterPro IPR014922
DTO10_12760	COG0840	transmembrane signaling receptor activity
DTO10_12765	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_12775	COG1278	Cold shock
DTO10_12795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DTO10_12800	COG0493	'glutamate synthase
DTO10_12805	COG0167	dihydroorotate dehydrogenase activity
DTO10_12825	COG3835	regulator
DTO10_12865	COG1597	lipid kinase activity
DTO10_12870	COG0025	NhaP-type Na H and K H
DTO10_12890	COG3842	ATPase activity
DTO10_12895	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_12905	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DTO10_12910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_12920	COG4821	SIS domain
DTO10_12930	COG0363	glucosamine-6-phosphate deaminase activity
DTO10_12935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_12940	COG1263	PTS System
DTO10_12940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_12940	COG2190	(PTS) system
DTO10_12945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DTO10_12960	COG2814	Major facilitator Superfamily
DTO10_12965	COG1846	Transcriptional regulator
DTO10_12970	COG2822	iron ion transport
DTO10_12975	COG2837	iron assimilation
DTO10_12980	COG0672	)-iron permease
DTO10_12990	COG0789	Transcriptional regulator
DTO10_12995	COG1253	flavin adenine dinucleotide binding
DTO10_13005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DTO10_13010	COG2208	phosphoserine phosphatase activity
DTO10_13065	COG4974	Belongs to the 'phage' integrase family
DTO10_13070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DTO10_13115	COG1181	Belongs to the D-alanine--D-alanine ligase family
DTO10_13120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DTO10_13125	COG2208	phosphoserine phosphatase activity
DTO10_13130	COG0513	Belongs to the DEAD box helicase family
DTO10_13135	COG3402	PFAM membrane-flanked domain
DTO10_13140	COG3428	Bacterial PH domain
DTO10_13145	COG0705	Rhomboid family
DTO10_13150	COG0736	holo-[acyl-carrier-protein] synthase activity
DTO10_13155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DTO10_13165	COG0864	Transcriptional regulator
DTO10_13170	COG2337	Toxic component of a toxin-antitoxin (TA) module
DTO10_13175	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_13180	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_13185	COG2172	sigma factor antagonist activity
DTO10_13190	COG2208	phosphoserine phosphatase activity
DTO10_13195	COG1366	Belongs to the anti-sigma-factor antagonist family
DTO10_13200	COG2172	sigma factor antagonist activity
DTO10_13205	COG1191	sigma factor activity
DTO10_13210	COG2208	phosphoserine phosphatase activity
DTO10_13215	COG2183	response to ionizing radiation
DTO10_13305	COG0802	atpase or kinase
DTO10_13310	COG1214	PFAM Peptidase M22, glycoprotease
DTO10_13315	COG0456	acetyltransferase
DTO10_13325	COG0488	(ABC) transporter
DTO10_13330	COG0315	cyclic pyranopterin monophosphate synthase activity
DTO10_13335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DTO10_13345	COG1266	CAAX protease self-immunity
DTO10_13380	COG0747	negative chemotaxis
DTO10_13385	COG0601	transmembrane transport
DTO10_13390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_13395	COG0444	Belongs to the ABC transporter superfamily
DTO10_13400	COG4608	Belongs to the ABC transporter superfamily
DTO10_13405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DTO10_13415	COG1940	carbohydrate kinase activity
DTO10_13440	COG1136	(ABC) transporter
DTO10_13455	COG1070	Carbohydrate kinase
DTO10_13465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DTO10_13475	COG4585	Histidine kinase
DTO10_13480	COG2197	response regulator
DTO10_13485	COG1404	Belongs to the peptidase S8 family
DTO10_13500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_13505	COG2011	ABC-type metal ion transport system permease component
DTO10_13510	COG1464	Belongs to the NlpA lipoprotein family
DTO10_13520	COG1686	Belongs to the peptidase S11 family
DTO10_13525	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_13530	COG0028	Belongs to the TPP enzyme family
DTO10_13535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_13540	COG1288	antiporter activity
DTO10_13560	COG2986	histidine ammonia-lyase
DTO10_13570	COG1228	amidohydrolase
DTO10_13580	COG0517	IMP dehydrogenase activity
DTO10_13580	COG4175	Glycine betaine
DTO10_13585	COG2113	Glycine betaine
DTO10_13600	COG4842	Belongs to the WXG100 family
DTO10_13605	COG5417	Belongs to the EsaB family
DTO10_13610	COG4499	WXG100 protein secretion system (Wss), protein YukC
DTO10_13615	COG1674	ftsk spoiiie
DTO10_13620	COG1511	domain protein
DTO10_13630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_13640	COG0714	Associated with various cellular activities
DTO10_13645	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DTO10_13650	COG1305	Transglutaminase-like
DTO10_13655	COG0519	Catalyzes the synthesis of GMP from XMP
DTO10_13655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DTO10_13660	COG2252	PERMEase
DTO10_13665	COG3711	transcriptional antiterminator
DTO10_13670	COG2190	(PTS) system
DTO10_13670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_13670	COG1263	PTS System
DTO10_13705	COG2814	Major facilitator Superfamily
DTO10_13715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DTO10_13720	COG2814	Major facilitator Superfamily
DTO10_13730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DTO10_13755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DTO10_13760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DTO10_13765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DTO10_13775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DTO10_13780	COG0047	phosphoribosylformylglycinamidine synthase activity
DTO10_13790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DTO10_13800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DTO10_13810	COG0151	Belongs to the GarS family
DTO10_13825	COG1470	cell adhesion involved in biofilm formation
DTO10_13830	COG4496	protein, YerC YecD
DTO10_13835	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DTO10_13840	COG0210	DNA helicase
DTO10_13845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DTO10_13850	COG4851	CamS sex pheromone cAM373 precursor
DTO10_13855	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_13860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DTO10_13865	COG0154	amidase activity
DTO10_13870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DTO10_13875	COG1595	DNA-templated transcription, initiation
DTO10_13895	COG1597	lipid kinase activity
DTO10_13900	COG0456	acetyltransferase
DTO10_13915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_13920	COG2323	membrane
DTO10_13935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_13960	COG0004	ammonium transporteR
DTO10_13985	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DTO10_13990	COG3853	Toxic anion resistance protein (TelA)
DTO10_13995	COG0778	Nitroreductase
DTO10_14005	COG1404	Belongs to the peptidase S8 family
DTO10_14010	COG4549	nuclear export factor GLE1
DTO10_14015	COG2372	response to copper ion
DTO10_14015	COG1276	copper resistance
DTO10_14020	COG2514	catechol 2,3-dioxygenase activity
DTO10_14030	COG5002	protein histidine kinase activity
DTO10_14035	COG0398	Pfam SNARE associated Golgi protein
DTO10_14040	COG4708	membrane
DTO10_14045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DTO10_14065	COG2204	response regulator
DTO10_14070	COG5002	protein histidine kinase activity
DTO10_14080	COG2234	aminopeptidase activity
DTO10_14095	COG5444	nuclease activity
DTO10_14115	COG2733	membrane
DTO10_14130	COG5002	protein histidine kinase activity
DTO10_14130	COG3850	Histidine kinase
DTO10_14135	COG0577	efflux transmembrane transporter activity
DTO10_14140	COG1136	(ABC) transporter
DTO10_14150	COG0596	Alpha beta hydrolase
DTO10_14160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_14185	COG1609	Transcriptional regulator
DTO10_14195	COG0673	inositol 2-dehydrogenase activity
DTO10_14200	COG0673	inositol 2-dehydrogenase activity
DTO10_14210	COG1187	pseudouridine synthase activity
DTO10_14215	COG0697	spore germination
DTO10_14225	COG0667	Aldo Keto reductase
DTO10_14230	COG1114	Component of the transport system for branched-chain amino acids
DTO10_14245	COG1129	ABC transporter
DTO10_14250	COG1172	Belongs to the binding-protein-dependent transport system permease family
DTO10_14265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DTO10_14275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DTO10_14285	COG1845	cytochrome c oxidase, subunit III
DTO10_14310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DTO10_14315	COG0527	aspartate kinase activity
DTO10_14320	COG1668	transmembrane transport
DTO10_14330	COG0778	Nitroreductase
DTO10_14335	COG1132	(ABC) transporter
DTO10_14340	COG1132	(ABC) transporter
DTO10_14345	COG1966	Carbon starvation protein
DTO10_14350	COG2879	small protein
DTO10_14355	COG0004	ammonium transporteR
DTO10_14360	COG0347	Belongs to the P(II) protein family
DTO10_14370	COG3279	Response regulator of the LytR AlgR family
DTO10_14375	COG0427	acetyl-CoA hydrolase
DTO10_14380	COG0628	permease
DTO10_14385	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_14390	COG1301	dicarboxylic acid transport
DTO10_14395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DTO10_14400	COG1263	PTS System
DTO10_14400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_14405	COG0366	Alpha amylase catalytic
DTO10_14410	COG2188	Transcriptional regulator
DTO10_14415	COG3584	3D domain protein
DTO10_14415	COG3583	domain protein
DTO10_14420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_14425	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DTO10_14440	COG2027	D-alanyl-D-alanine carboxypeptidase
DTO10_14445	COG0546	phosphoglycolate phosphatase activity
DTO10_14455	COG1335	isochorismatase
DTO10_14460	COG0778	Nitroreductase
DTO10_14465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DTO10_14475	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_14485	COG0243	molybdopterin cofactor binding
DTO10_14490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_14495	COG5002	protein histidine kinase activity
DTO10_14500	COG0513	Belongs to the DEAD box helicase family
DTO10_14515	COG0626	cystathionine gamma-synthase activity
DTO10_14525	COG0307	riboflavin synthase, alpha
DTO10_14530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_14530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_14540	COG2404	hydrolase activity, acting on ester bonds
DTO10_14545	COG1295	ribonuclease BN
DTO10_14555	COG0475	glutathione-regulated potassium exporter activity
DTO10_14560	COG0490	domain, Protein
DTO10_14565	COG0582	viral genome integration into host DNA
DTO10_14570	COG1077	Cell shape determining protein MreB Mrl
DTO10_14575	COG3180	Ammonia monooxygenase
DTO10_14580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DTO10_14585	COG1360	Flagellar Motor Protein
DTO10_14595	COG0693	protein deglycase activity
DTO10_14600	COG0024	Methionine aminopeptidase
DTO10_14610	COG1763	Mo-molybdopterin cofactor biosynthetic process
DTO10_14615	COG0303	'Molybdopterin
DTO10_14620	COG4840	Belongs to the UPF0435 family
DTO10_14630	COG1295	ribonuclease BN
DTO10_14635	COG2217	Heavy metal translocating P-type atpase
DTO10_14640	COG0477	Major facilitator Superfamily
DTO10_14645	COG0387	Pfam Sodium calcium exchanger
DTO10_14655	COG0535	radical SAM domain protein
DTO10_14680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DTO10_14685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DTO10_14690	COG4807	Protein conserved in bacteria
DTO10_14695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_14700	COG0765	amino acid transport
DTO10_14705	COG1126	abc transporter atp-binding protein
DTO10_14720	COG1840	ABC-type Fe3 transport system, periplasmic component
DTO10_14735	COG0165	Argininosuccinate lyase
DTO10_14745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_14755	COG1113	amino acid transport
DTO10_14765	COG1113	amino acid transport
DTO10_14770	COG0531	amino acid
DTO10_14820	COG1131	(ABC) transporter
DTO10_14825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DTO10_14835	COG2235	arginine
DTO10_14845	COG4187	Peptidase family M20/M25/M40
DTO10_14855	COG0833	amino acid
DTO10_14860	COG3069	C4-dicarboxylate transmembrane transporter activity
DTO10_14890	COG1136	(ABC) transporter
DTO10_14895	COG0577	efflux transmembrane transporter activity
DTO10_14905	COG2205	protein histidine kinase activity
DTO10_14910	COG0745	RESPONSE REGULATOR receiver
DTO10_14925	COG1126	abc transporter atp-binding protein
DTO10_14930	COG0765	amino acid transport
DTO10_14935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_14945	COG1090	epimerase
DTO10_14950	COG0436	Aminotransferase
DTO10_14980	COG0791	NLP P60 protein
DTO10_14980	COG1388	LysM domain
DTO10_14995	COG1695	Transcriptional regulator
DTO10_15010	COG0385	Bile acid
DTO10_15020	COG2814	Major facilitator Superfamily
DTO10_15040	COG0166	Belongs to the GPI family
DTO10_15045	COG0628	permease
DTO10_15055	COG0765	amino acid transport
DTO10_15070	COG0583	DNA-binding transcription factor activity
DTO10_15090	COG1960	acyl-CoA dehydrogenase activity
DTO10_15095	COG0183	Belongs to the thiolase family
DTO10_15115	COG1090	epimerase
DTO10_15140	COG1988	membrane-bound metal-dependent
DTO10_15145	COG1194	a g-specific adenine glycosylase
DTO10_15160	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_15175	COG3557	Belongs to the UPF0374 family
DTO10_15180	COG1132	(ABC) transporter
DTO10_15195	COG0655	NAD(P)H dehydrogenase (quinone) activity
DTO10_15200	COG2814	Major facilitator Superfamily
DTO10_15205	COG1566	PFAM secretion protein HlyD family protein
DTO10_15210	COG1846	Transcriptional regulator
DTO10_15215	COG4129	membrane
DTO10_15220	COG0070	glutamate synthase
DTO10_15220	COG0069	glutamate synthase activity
DTO10_15220	COG0067	glutamate synthase
DTO10_15225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DTO10_15235	COG4555	ABC transporter
DTO10_15250	COG1607	acyl-coa hydrolase
DTO10_15255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DTO10_15265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DTO10_15285	COG0735	belongs to the Fur family
DTO10_15390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DTO10_15490	COG4974	Belongs to the 'phage' integrase family
DTO10_15570	COG2066	Belongs to the glutaminase family
DTO10_15580	COG0582	viral genome integration into host DNA
DTO10_15595	COG2814	Major facilitator Superfamily
DTO10_15605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_15615	COG5002	protein histidine kinase activity
DTO10_15620	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_15645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DTO10_15650	COG5577	PFAM Coat F domain
DTO10_15675	COG1388	LysM domain
DTO10_15680	COG4129	membrane
DTO10_15710	COG0745	RESPONSE REGULATOR receiver
DTO10_15745	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_15755	COG1247	-acetyltransferase
DTO10_15765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DTO10_15790	COG0346	lactoylglutathione lyase activity
DTO10_15810	COG0393	Putative heavy-metal-binding
DTO10_15835	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DTO10_15850	COG3773	Cell wall hydrolase
DTO10_15885	COG3773	Cell wall hydrolase
DTO10_15900	COG1846	Transcriptional regulator
DTO10_15900	COG0456	acetyltransferase
DTO10_15915	COG0697	spore germination
DTO10_15920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_15930	COG0114	fumarate hydratase activity
DTO10_15935	COG0697	spore germination
DTO10_15950	COG0531	amino acid
DTO10_15955	COG0531	amino acid
DTO10_15970	COG2610	gluconate transmembrane transporter activity
DTO10_15985	COG1802	Transcriptional regulator
DTO10_15990	COG2084	Dehydrogenase
DTO10_16005	COG2610	gluconate transmembrane transporter activity
DTO10_16025	COG1141	Ferredoxin
DTO10_16030	COG4638	Rieske (2fe-2S)
DTO10_16035	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_16040	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_16045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DTO10_16050	COG1011	Hydrolase
DTO10_16055	COG3290	protein histidine kinase activity
DTO10_16055	COG3829	transcription factor binding
DTO10_16075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DTO10_16085	COG1984	allophanate hydrolase subunit 2
DTO10_16095	COG0439	Biotin carboxylase
DTO10_16100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_16105	COG3290	protein histidine kinase activity
DTO10_16105	COG3829	transcription factor binding
DTO10_16120	COG1309	transcriptional regulator
DTO10_16125	COG0477	Major facilitator Superfamily
DTO10_16135	COG0640	Transcriptional regulator
DTO10_16145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_16150	COG0697	spore germination
DTO10_16170	COG1473	amidohydrolase
DTO10_16185	COG0586	Pfam SNARE associated Golgi protein
DTO10_16195	COG1473	amidohydrolase
DTO10_16205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DTO10_16235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DTO10_16240	COG1280	lysine exporter protein (LysE YggA)
DTO10_16275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_16285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_16290	COG0805	protein transport
DTO10_16300	COG2205	protein histidine kinase activity
DTO10_16305	COG2723	6-phospho-beta-galactosidase activity
DTO10_16310	COG2188	Transcriptional regulator
DTO10_16315	COG2814	Major facilitator Superfamily
DTO10_16335	COG2076	Multidrug Resistance protein
DTO10_16340	COG2076	Multidrug Resistance protein
DTO10_16350	COG0745	RESPONSE REGULATOR receiver
DTO10_16355	COG1132	(ABC) transporter
DTO10_16360	COG2130	NADP-dependent
DTO10_16365	COG1289	transmembrane transporter activity
DTO10_16380	COG3382	B3 4 domain protein
DTO10_16385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DTO10_16395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DTO10_16400	COG0778	Nitroreductase
DTO10_16405	COG1120	ATPase activity
DTO10_16410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DTO10_16415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DTO10_16425	COG0784	Response regulator, receiver
DTO10_16430	COG4191	Histidine kinase
DTO10_16440	COG0531	amino acid
DTO10_16445	COG1115	amino acid carrier protein
DTO10_16450	COG2766	serine protein kinase
DTO10_16470	COG2718	Belongs to the UPF0229 family
DTO10_16490	COG0322	excinuclease ABC activity
DTO10_16575	COG0322	excinuclease ABC activity
DTO10_16615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DTO10_16645	COG1702	phosphate starvation-inducible protein PhoH
DTO10_16655	COG0756	dUTP diphosphatase activity
DTO10_16665	COG3584	3D domain protein
DTO10_16810	COG1652	LysM domain
DTO10_16815	COG3584	3D domain protein
DTO10_16815	COG1388	LysM domain
DTO10_16825	COG3628	GPW Gp25 family protein
DTO10_16830	COG3299	homolog of phage Mu protein gp47
DTO10_16875	COG1876	peptidase activity
DTO10_16910	COG1674	ftsk spoiiie
DTO10_16940	COG2807	transmembrane transport
DTO10_16945	COG2186	Transcriptional regulator
DTO10_16950	COG1113	amino acid transport
DTO10_16990	COG0531	amino acid
DTO10_17020	COG0385	Bile acid
DTO10_17030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DTO10_17045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DTO10_17050	COG2068	MobA-Related Protein
DTO10_17055	COG2094	Belongs to the DNA glycosylase MPG family
DTO10_17060	COG0477	Major facilitator Superfamily
DTO10_17065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DTO10_17070	COG0277	FAD linked oxidase domain protein
DTO10_17075	COG0412	Dienelactone hydrolase
DTO10_17080	COG0686	Belongs to the AlaDH PNT family
DTO10_17085	COG2217	Heavy metal translocating P-type atpase
DTO10_17090	COG2508	Transcriptional regulator
DTO10_17090	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DTO10_17095	COG0306	phosphate transporter
DTO10_17100	COG1392	Phosphate transport regulator
DTO10_17105	COG0306	phosphate transporter
DTO10_17110	COG0656	L-ascorbic acid biosynthetic process
DTO10_17115	COG2261	transglycosylase associated protein
DTO10_17120	COG0564	pseudouridine synthase activity
DTO10_17135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DTO10_17140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_17140	COG3153	acetyltransferase
DTO10_17145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DTO10_17155	COG0431	NADPH-dependent FMN reductase
DTO10_17175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DTO10_17185	COG1473	amidohydrolase
DTO10_17195	COG4948	Mandelate Racemase Muconate Lactonizing
DTO10_17200	COG3949	Membrane
DTO10_17205	COG2719	SpoVR family
DTO10_17210	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_17215	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_17240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_17290	COG3655	Transcriptional regulator
DTO10_17305	COG0640	Transcriptional regulator
DTO10_17310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DTO10_17315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DTO10_17320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_17325	COG0840	transmembrane signaling receptor activity
DTO10_17330	COG3437	response regulator, receiver
DTO10_17330	COG0784	Response regulator, receiver
DTO10_17340	COG0398	Pfam SNARE associated Golgi protein
DTO10_17345	COG0745	RESPONSE REGULATOR receiver
DTO10_17350	COG3850	Histidine kinase
DTO10_17350	COG5002	protein histidine kinase activity
DTO10_17355	COG1522	sequence-specific DNA binding
DTO10_17360	COG2059	Chromate
DTO10_17365	COG2059	Chromate
DTO10_17375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DTO10_17380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DTO10_17390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_17395	COG3162	membrane
DTO10_17400	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DTO10_17405	COG0492	ferredoxin-NADP+ reductase activity
DTO10_17410	COG1141	Ferredoxin
DTO10_17415	COG3396	Phenylacetate-CoA oxygenase
DTO10_17440	COG1024	Enoyl-CoA hydratase
DTO10_17445	COG1024	Enoyl-CoA hydratase
DTO10_17450	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_17455	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_17460	COG0183	Belongs to the thiolase family
DTO10_17465	COG1024	Enoyl-CoA hydratase
DTO10_17470	COG3327	negative regulation of DNA-templated transcription, initiation
DTO10_17500	COG0745	RESPONSE REGULATOR receiver
DTO10_17505	COG5002	protein histidine kinase activity
DTO10_17510	COG1393	Belongs to the ArsC family
DTO10_17520	COG1393	Belongs to the ArsC family
DTO10_17530	COG1393	Belongs to the ArsC family
DTO10_17540	COG4149	molybdate abc transporter
DTO10_17560	COG1278	Cold shock
DTO10_17565	COG0716	FMN binding
DTO10_17570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_17575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DTO10_17580	COG1227	inorganic diphosphatase activity
DTO10_17585	COG0659	secondary active sulfate transmembrane transporter activity
DTO10_17600	COG1960	acyl-CoA dehydrogenase activity
DTO10_17605	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_17610	COG1024	Enoyl-CoA hydratase
DTO10_17615	COG0183	Belongs to the thiolase family
DTO10_17620	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_17630	COG2271	Major facilitator Superfamily
DTO10_17650	COG2814	Major facilitator Superfamily
DTO10_17655	COG2851	Citrate transporter
DTO10_17675	COG0456	acetyltransferase
DTO10_17685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_17705	COG1253	flavin adenine dinucleotide binding
DTO10_17710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_17720	COG0586	Pfam SNARE associated Golgi protein
DTO10_17725	COG1253	flavin adenine dinucleotide binding
DTO10_17730	COG3852	Histidine kinase
DTO10_17735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DTO10_17740	COG0589	response to stress
DTO10_17745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_17755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DTO10_17770	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_17780	COG1113	amino acid transport
DTO10_17785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DTO10_17790	COG1522	sequence-specific DNA binding
DTO10_17800	COG1522	sequence-specific DNA binding
DTO10_17810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_17815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DTO10_17880	COG0753	catalase activity
DTO10_17885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DTO10_17895	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_17910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DTO10_17915	COG0517	IMP dehydrogenase activity
DTO10_17915	COG0516	GMP reductase activity
DTO10_17935	COG1132	(ABC) transporter
DTO10_17940	COG1132	(ABC) transporter
DTO10_17945	COG0254	rRNA binding
DTO10_17950	COG0626	cystathionine gamma-synthase activity
DTO10_17955	COG0626	cystathionine gamma-synthase activity
DTO10_17960	COG0114	fumarate hydratase activity
DTO10_17970	COG3842	ATPase activity
DTO10_17975	COG2508	Transcriptional regulator
DTO10_17985	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DTO10_18000	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DTO10_18010	COG1464	Belongs to the NlpA lipoprotein family
DTO10_18015	COG2011	ABC-type metal ion transport system permease component
DTO10_18020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DTO10_18030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DTO10_18055	COG0463	Glycosyl transferase, family 2
DTO10_18065	COG0672	)-iron permease
DTO10_18085	COG0189	ligase activity
DTO10_18090	COG0189	ligase activity
DTO10_18095	COG0189	ligase activity
DTO10_18100	COG0189	ligase activity
DTO10_18110	COG3679	Belongs to the UPF0342 family
DTO10_18115	COG0561	phosphatase activity
DTO10_18140	COG0832	Belongs to the urease beta subunit family
DTO10_18165	COG1834	amidinotransferase
DTO10_18170	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_18175	COG1024	Enoyl-CoA hydratase
DTO10_18190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DTO10_18195	COG0420	3'-5' exonuclease activity
DTO10_18200	COG4717	serine-type aminopeptidase activity
DTO10_18215	COG1120	ATPase activity
DTO10_18235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DTO10_18265	COG1846	Transcriptional regulator
DTO10_18270	COG4980	gas vesicle protein
DTO10_18290	COG0537	adenosine 5'-monophosphoramidase activity
DTO10_18295	COG1131	(ABC) transporter
DTO10_18300	COG4473	ABC transporter
DTO10_18310	COG1473	amidohydrolase
DTO10_18315	COG0671	phosphoesterase, PA-phosphatase related
DTO10_18320	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_18325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DTO10_18335	COG1309	transcriptional regulator
DTO10_18345	COG1234	tRNA 3'-trailer cleavage
DTO10_18350	COG0095	Lipoate-protein ligase
DTO10_18355	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_18360	COG1418	mRNA catabolic process
DTO10_18370	COG0501	Belongs to the peptidase M48B family
DTO10_18375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_18385	COG4903	ComK protein
DTO10_18395	COG2333	competence protein COMEC
DTO10_18395	COG0658	competence protein
DTO10_18405	COG0398	Pfam SNARE associated Golgi protein
DTO10_18415	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DTO10_18460	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_18470	COG2311	Membrane
DTO10_18485	COG0367	asparagine synthase
DTO10_18495	COG2182	Extracellular solute-binding protein
DTO10_18505	COG0366	Alpha amylase catalytic
DTO10_18510	COG1609	Transcriptional regulator
DTO10_18520	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_18525	COG1666	GTP binding
DTO10_18535	COG1307	EDD domain protein, DegV family
DTO10_18540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DTO10_18545	COG3729	General stress protein
DTO10_18555	COG0561	phosphatase activity
DTO10_18560	COG1073	alpha beta
DTO10_18565	COG2151	metal-sulfur cluster biosynthetic enzyme
DTO10_18570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DTO10_18575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DTO10_18580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DTO10_18585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DTO10_18590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DTO10_18600	COG0505	Belongs to the CarA family
DTO10_18610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DTO10_18625	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_18640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DTO10_18645	COG0542	response to heat
DTO10_18655	COG2267	carboxylic ester hydrolase activity
DTO10_18675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_18680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DTO10_18685	COG5504	Zn-dependent protease
DTO10_18695	COG0180	Tryptophanyl-tRNA synthetase
DTO10_18710	COG0456	acetyltransferase
DTO10_18715	COG1393	Belongs to the ArsC family
DTO10_18720	COG4862	establishment of competence for transformation
DTO10_18725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_18730	COG4469	Competence protein
DTO10_18735	COG1164	Oligoendopeptidase f
DTO10_18750	COG2346	COG2346, Truncated hemoglobins
DTO10_18755	COG0741	lytic transglycosylase activity
DTO10_18760	COG4116	CYTH
DTO10_18765	COG2357	RelA SpoT domain protein
DTO10_18770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DTO10_18775	COG0564	pseudouridine synthase activity
DTO10_18785	COG2239	Acts as a magnesium transporter
DTO10_18790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DTO10_18835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DTO10_18855	COG0210	DNA helicase
DTO10_18870	COG2153	protein acetylation
DTO10_18875	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DTO10_18880	COG2382	esterase
DTO10_18885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DTO10_18900	COG0693	protein deglycase activity
DTO10_18925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DTO10_18930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_18935	COG1960	acyl-CoA dehydrogenase activity
DTO10_18950	COG5337	Spore coat protein CotH
DTO10_18960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_18965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_18980	COG2814	Major facilitator Superfamily
DTO10_18985	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_18990	COG0673	inositol 2-dehydrogenase activity
DTO10_19000	COG1902	pentaerythritol trinitrate reductase activity
DTO10_19005	COG2272	Belongs to the type-B carboxylesterase lipase family
DTO10_19010	COG3844	kynureninase activity
DTO10_19015	COG1113	amino acid transport
DTO10_19020	COG3483	tryptophan 2,3-dioxygenase activity
DTO10_19025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DTO10_19030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DTO10_19035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DTO10_19045	COG4208	sulfate ABC transporter
DTO10_19055	COG2239	Acts as a magnesium transporter
DTO10_19070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DTO10_19085	COG3883	PFAM NLP P60 protein
DTO10_19085	COG0791	NLP P60 protein
DTO10_19100	COG2017	converts alpha-aldose to the beta-anomer
DTO10_19105	COG0531	amino acid
DTO10_19110	COG5583	Uncharacterized small protein (DUF2292)
DTO10_19125	COG1278	Cold shock
DTO10_19135	COG2309	aminopeptidase activity
DTO10_19140	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_19145	COG0477	Major facilitator Superfamily
DTO10_19155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DTO10_19160	COG0352	thiamine-phosphate diphosphorylase activity
DTO10_19160	COG0351	phosphomethylpyrimidine kinase
DTO10_19170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DTO10_19185	COG1247	-acetyltransferase
DTO10_19195	COG1132	(ABC) transporter
DTO10_19200	COG2318	DinB family
DTO10_19205	COG1876	peptidase activity
DTO10_19210	COG1607	acyl-coa hydrolase
DTO10_19215	COG0670	Belongs to the BI1 family
DTO10_19225	COG4608	Belongs to the ABC transporter superfamily
DTO10_19230	COG0601	transmembrane transport
DTO10_19235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_19245	COG1363	Peptidase, m42
DTO10_19250	COG3871	stress protein (general stress protein 26)
DTO10_19260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DTO10_19260	COG0189	ligase activity
DTO10_19265	COG1404	Belongs to the peptidase S8 family
DTO10_19265	COG4412	M6 family metalloprotease domain protein
DTO10_19270	COG0706	membrane insertase activity
DTO10_19285	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_19295	COG1764	response to oxidative stress
DTO10_19300	COG1725	Transcriptional regulator
DTO10_19305	COG1131	(ABC) transporter
DTO10_19325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DTO10_19335	COG0772	Belongs to the SEDS family
DTO10_19350	COG0861	Integral membrane protein TerC family
DTO10_19355	COG1191	sigma factor activity
DTO10_19370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DTO10_19375	COG3852	Histidine kinase
DTO10_19380	COG1960	acyl-CoA dehydrogenase activity
DTO10_19385	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_19390	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_19395	COG1309	transcriptional regulator
DTO10_19400	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_19405	COG1024	Enoyl-CoA hydratase
DTO10_19425	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_19430	COG1024	Enoyl-CoA hydratase
DTO10_19450	COG3594	Acyltransferase
DTO10_19455	COG5002	protein histidine kinase activity
DTO10_19470	COG2223	nitrite transmembrane transporter activity
DTO10_19475	COG3852	Histidine kinase
DTO10_19480	COG1846	Transcriptional regulator
DTO10_19490	COG3949	Membrane
DTO10_19500	COG4873	Protein conserved in bacteria
DTO10_19520	COG1525	nuclease
DTO10_19530	COG0390	transport system, permease component
DTO10_19540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DTO10_19550	COG2084	Dehydrogenase
DTO10_19560	COG0436	Aminotransferase
DTO10_19565	COG0598	Magnesium transport protein CorA
DTO10_19570	COG1714	RDD family
DTO10_19575	COG0784	Response regulator, receiver
DTO10_19575	COG0835	chemotaxis
DTO10_19590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DTO10_19595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DTO10_19600	COG1408	metallophosphoesterase
DTO10_19605	COG0490	domain, Protein
DTO10_19605	COG0471	metal ion transport
DTO10_19610	COG2200	EAL domain
DTO10_19635	COG4703	Protein of unknown function (DUF1797)
DTO10_19640	COG0517	IMP dehydrogenase activity
DTO10_19645	COG0477	Major facilitator Superfamily
DTO10_19650	COG0583	DNA-binding transcription factor activity
DTO10_19655	COG2171	N-acyltransferase activity
DTO10_19660	COG1473	amidohydrolase
DTO10_19665	COG0569	domain protein
DTO10_19670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_19685	COG0561	phosphatase activity
DTO10_19710	COG0022	dehydrogenase e1 component
DTO10_19715	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_19730	COG0726	polysaccharide deacetylase
DTO10_19760	COG1982	Orn Lys Arg decarboxylase major
DTO10_19770	COG4476	Belongs to the UPF0223 family
DTO10_19780	COG0512	Glutamine amidotransferase of anthranilate synthase
DTO10_19820	COG0483	inositol monophosphate 1-phosphatase activity
DTO10_19850	COG4896	Protein conserved in bacteria
DTO10_19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DTO10_19865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DTO10_19870	COG4838	Belongs to the UPF0358 family
DTO10_19875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DTO10_19880	COG1612	heme a metabolic process
DTO10_19885	COG0109	protoheme IX farnesyltransferase activity
DTO10_19910	COG3336	cytochrome c oxidase
DTO10_19925	COG2340	Cysteine-rich secretory protein family
DTO10_19950	COG3679	Belongs to the UPF0342 family
DTO10_19960	COG4471	UPF0298 protein
DTO10_19970	COG0742	ribosomal rna small subunit methyltransferase
DTO10_19975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DTO10_19980	COG3314	Sporulation integral membrane protein YlbJ
DTO10_19985	COG1752	Esterase of the alpha-beta hydrolase superfamily
DTO10_19990	COG3480	Lon protease (S16) C-terminal proteolytic domain
DTO10_19995	COG1323	Belongs to the UPF0348 family
DTO10_20000	COG1399	metal-binding, possibly nucleic acid-binding protein
DTO10_20010	COG1024	Enoyl-CoA hydratase
DTO10_20020	COG0454	-acetyltransferase
DTO10_20025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DTO10_20035	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DTO10_20040	COG2001	Belongs to the MraZ family
DTO10_20060	COG0768	penicillin binding
DTO10_20070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DTO10_20075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DTO10_20080	COG0772	Belongs to the SEDS family
DTO10_20085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DTO10_20090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DTO10_20095	COG3879	Bacterial protein of unknown function (DUF881)
DTO10_20100	COG3879	Bacterial protein of unknown function (DUF881)
DTO10_20105	COG3856	small basic protein
DTO10_20110	COG0849	cell division
DTO10_20115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DTO10_20125	COG1191	sigma factor activity
DTO10_20130	COG1191	sigma factor activity
DTO10_20135	COG1873	PFAM PRC-barrel domain
DTO10_20145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DTO10_20150	COG1799	cell septum assembly
DTO10_20155	COG0762	integral membrane protein
DTO10_20160	COG2302	S4 RNA-binding domain
DTO10_20165	COG3599	regulation of cell shape
DTO10_20175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DTO10_20180	COG0564	pseudouridine synthase activity
DTO10_20185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DTO10_20195	COG0540	Belongs to the ATCase OTCase family
DTO10_20210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DTO10_20220	COG0167	dihydroorotate dehydrogenase activity
DTO10_20230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DTO10_20240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DTO10_20245	COG1561	YicC-like family, N-terminal region
DTO10_20255	COG0194	GDP metabolic process
DTO10_20265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DTO10_20270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DTO10_20280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DTO10_20285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DTO10_20285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DTO10_20295	COG0631	protein serine/threonine phosphatase activity
DTO10_20300	COG0515	serine threonine protein kinase
DTO10_20300	COG2815	serine threonine protein kinase
DTO10_20305	COG1162	GTPase activity
DTO10_20310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DTO10_20315	COG1564	THIamine pyrophosphokinase
DTO10_20325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DTO10_20330	COG1302	Protein conserved in bacteria
DTO10_20335	COG1461	Dihydroxyacetone kinase
DTO10_20340	COG1760	l-serine dehydratase
DTO10_20345	COG1760	l-serine dehydratase
DTO10_20350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DTO10_20355	COG1349	DNA-binding transcription factor activity
DTO10_20365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DTO10_20370	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_20375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DTO10_20380	COG0571	ribonuclease III activity
DTO10_20385	COG1196	nuclear chromosome segregation
DTO10_20390	COG0552	protein localization to endoplasmic reticulum
DTO10_20400	COG1131	(ABC) transporter
DTO10_20415	COG0714	Associated with various cellular activities
DTO10_20440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DTO10_20445	COG0228	four-way junction DNA binding
DTO10_20450	COG1837	Belongs to the UPF0109 family
DTO10_20460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DTO10_20465	COG0336	Belongs to the RNA methyltransferase TrmD family
DTO10_20470	COG0335	large ribosomal subunit rRNA binding
DTO10_20480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DTO10_20485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DTO10_20510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_20520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DTO10_20525	COG0758	DNA mediated transformation
DTO10_20530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DTO10_20535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DTO10_20540	COG4974	Belongs to the 'phage' integrase family
DTO10_20550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DTO10_20555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DTO10_20560	COG1815	bacterial-type flagellum-dependent cell motility
DTO10_20565	COG1558	bacterial-type flagellum-dependent cell motility
DTO10_20570	COG1677	Flagellar hook-basal body complex protein FliE
DTO10_20575	COG1766	The M ring may be actively involved in energy transduction
DTO10_20580	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_20585	COG1317	bacterial-type flagellum organization
DTO10_20590	COG1157	protein secretion by the type III secretion system
DTO10_20595	COG2882	bacterial-type flagellum organization
DTO10_20610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DTO10_20625	COG1582	Flagellar protein (FlbD)
DTO10_20630	COG1580	Controls the rotational direction of flagella during chemotaxis
DTO10_20635	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_20640	COG1776	CheC inhibitor of MCP methylation
DTO10_20640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DTO10_20645	COG2201	protein-glutamate methylesterase activity
DTO10_20650	COG3190	flagellar
DTO10_20655	COG1338	Plays a role in the flagellum-specific transport system
DTO10_20660	COG1987	bacterial-type flagellum assembly
DTO10_20665	COG1684	flagellar biosynthetic protein fliR
DTO10_20670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_20675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DTO10_20680	COG1419	protein localization to endoplasmic reticulum
DTO10_20685	COG0455	bacterial-type flagellum organization
DTO10_20690	COG2201	protein-glutamate methylesterase activity
DTO10_20695	COG2201	protein-glutamate methylesterase activity
DTO10_20700	COG0643	Histidine kinase
DTO10_20700	COG2198	Histidine kinase
DTO10_20705	COG0835	chemotaxis
DTO10_20710	COG1776	CheC inhibitor of MCP methylation
DTO10_20715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DTO10_20720	COG1191	sigma factor activity
DTO10_20745	COG0528	UMP kinase activity
DTO10_20760	COG4589	Belongs to the CDS family
DTO10_20765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DTO10_20770	COG0750	zinc metalloprotease
DTO10_20780	COG2176	DNA-directed DNA polymerase activity
DTO10_20785	COG0779	Required for maturation of 30S ribosomal subunits
DTO10_20790	COG0195	Participates in both transcription termination and antitermination
DTO10_20795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DTO10_20800	COG1358	cellular component organization or biogenesis
DTO10_20805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DTO10_20810	COG1550	Protein conserved in bacteria
DTO10_20815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DTO10_20820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DTO10_20825	COG0196	riboflavin kinase activity
DTO10_20835	COG1185	polyribonucleotide nucleotidyltransferase activity
DTO10_20840	COG0726	polysaccharide deacetylase
DTO10_20845	COG0612	Peptidase, M16
DTO10_20850	COG1873	PFAM PRC-barrel domain
DTO10_20855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_20860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DTO10_20865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DTO10_20870	COG0527	aspartate kinase activity
DTO10_20875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DTO10_20880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DTO10_20885	COG0740	serine-type endopeptidase activity
DTO10_20895	COG4980	gas vesicle protein
DTO10_20895	COG1674	ftsk spoiiie
DTO10_20905	COG2188	Transcriptional regulator
DTO10_20930	COG0612	Peptidase, M16
DTO10_20935	COG0612	Peptidase, M16
DTO10_20940	COG0300	oxidoreductase activity
DTO10_20955	COG1426	Protein conserved in bacteria
DTO10_20960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DTO10_20965	COG1546	Belongs to the CinA family
DTO10_20965	COG1058	Belongs to the CinA family
DTO10_20970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DTO10_20980	COG1692	metallophosphoesterase
DTO10_20985	COG2359	stage V sporulation protein S
DTO10_20995	COG0674	pyruvate-flavodoxin oxidoreductase activity
DTO10_20995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DTO10_21000	COG1013	pyruvate-flavodoxin oxidoreductase activity
DTO10_21015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DTO10_21020	COG4550	Control of competence regulator ComK, YlbF/YmcA
DTO10_21030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DTO10_21040	COG0582	viral genome integration into host DNA
DTO10_21045	COG2856	Zn peptidase
DTO10_21080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_21085	COG0582	viral genome integration into host DNA
DTO10_21095	COG2132	Multicopper oxidase
DTO10_21105	COG1297	OPT oligopeptide transporter protein
DTO10_21115	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_21135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DTO10_21140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DTO10_21145	COG1447	Phosphotransferase system cellobiose-specific component IIA
DTO10_21150	COG1486	melibiose metabolic process
DTO10_21155	COG3394	polysaccharide catabolic process
DTO10_21160	COG1252	NADH dehydrogenase
DTO10_21180	COG1396	sequence-specific DNA binding
DTO10_21185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DTO10_21200	COG0745	RESPONSE REGULATOR receiver
DTO10_21205	COG5002	protein histidine kinase activity
DTO10_21210	COG1136	(ABC) transporter
DTO10_21215	COG0577	efflux transmembrane transporter activity
DTO10_21230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DTO10_21235	COG1923	regulation of RNA biosynthetic process
DTO10_21240	COG0464	growth
DTO10_21245	COG2860	membrane
DTO10_21250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DTO10_21255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DTO10_21260	COG0789	Transcriptional regulator
DTO10_21265	COG0174	glutamine synthetase
DTO10_21365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_21405	COG0860	N-Acetylmuramoyl-L-alanine amidase
DTO10_21460	COG2323	membrane
DTO10_21475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DTO10_21520	COG1902	pentaerythritol trinitrate reductase activity
DTO10_21575	COG0531	amino acid
DTO10_21635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DTO10_21640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DTO10_21645	COG0778	Nitroreductase
DTO10_21650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DTO10_21655	COG0716	FMN binding
DTO10_21675	COG0010	Belongs to the arginase family
DTO10_21680	COG0583	DNA-binding transcription factor activity
DTO10_21705	COG2720	vancomycin resistance protein
DTO10_21720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_21735	COG0583	DNA-binding transcription factor activity
DTO10_21775	COG0028	Belongs to the TPP enzyme family
DTO10_21790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DTO10_21810	COG1522	sequence-specific DNA binding
DTO10_21815	COG0405	Gamma-glutamyltransferase
DTO10_21825	COG2271	Major facilitator Superfamily
DTO10_21835	COG0626	cystathionine gamma-synthase activity
DTO10_21850	COG3604	Transcriptional regulator
DTO10_21855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_21860	COG0765	amino acid transport
DTO10_21865	COG1126	abc transporter atp-binding protein
DTO10_21870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DTO10_21895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_21905	COG1051	belongs to the nudix hydrolase family
DTO10_21920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DTO10_21925	COG1388	LysM domain
DTO10_21930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DTO10_21935	COG4224	UPF0291 protein
DTO10_21955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DTO10_21960	COG2271	Major facilitator Superfamily
DTO10_21965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_21985	COG3118	belongs to the thioredoxin family
DTO10_21990	COG1902	pentaerythritol trinitrate reductase activity
DTO10_21995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DTO10_22005	COG2259	Doxx family
DTO10_22010	COG0726	polysaccharide deacetylase
DTO10_22020	COG0785	Cytochrome C biogenesis protein
DTO10_22025	COG2201	protein-glutamate methylesterase activity
DTO10_22030	COG4846	Membrane protein involved in cytochrome C biogenesis
DTO10_22050	COG0419	ATPase involved in DNA repair
DTO10_22055	COG0071	Belongs to the small heat shock protein (HSP20) family
DTO10_22070	COG4187	Peptidase family M20/M25/M40
DTO10_22075	COG1288	antiporter activity
DTO10_22085	COG1024	Enoyl-CoA hydratase
DTO10_22100	COG1024	Enoyl-CoA hydratase
DTO10_22115	COG2151	metal-sulfur cluster biosynthetic enzyme
DTO10_22130	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_22135	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_22160	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_22170	COG0183	Belongs to the thiolase family
DTO10_22175	COG1960	acyl-CoA dehydrogenase activity
DTO10_22190	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_22220	COG0346	lactoylglutathione lyase activity
DTO10_22270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DTO10_22280	COG1414	Transcriptional regulator
DTO10_22285	COG1414	Transcriptional regulator
DTO10_22290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_22295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_22300	COG0183	Belongs to the thiolase family
DTO10_22325	COG1414	Transcriptional regulator
DTO10_22335	COG0824	Thioesterase
DTO10_22345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DTO10_22360	COG1522	sequence-specific DNA binding
DTO10_22380	COG1473	amidohydrolase
DTO10_22425	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_22435	COG2986	histidine ammonia-lyase
DTO10_22440	COG0833	amino acid
DTO10_22445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DTO10_22530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_22535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DTO10_22550	COG1116	anion transmembrane transporter activity
DTO10_22555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DTO10_22560	COG4521	taurine ABC transporter
DTO10_22570	COG4085	toxin activity
DTO10_22570	COG1525	nuclease
DTO10_22570	COG0737	Belongs to the 5'-nucleotidase family
DTO10_22580	COG0346	lactoylglutathione lyase activity
DTO10_22585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DTO10_22605	COG1819	glycosyl
DTO10_22615	COG1309	transcriptional regulator
DTO10_22620	COG0456	acetyltransferase
DTO10_22620	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DTO10_22645	COG0247	lactate metabolic process
DTO10_22650	COG0277	FAD linked oxidase domain protein
DTO10_22655	COG2186	Transcriptional regulator
DTO10_22675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DTO10_22680	COG2814	Major facilitator Superfamily
DTO10_22695	COG0697	spore germination
DTO10_22700	COG2364	Membrane
DTO10_22715	COG0596	Alpha beta hydrolase
DTO10_22740	COG1024	Enoyl-CoA hydratase
DTO10_22745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_22750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DTO10_22765	COG1802	Transcriptional regulator
DTO10_22770	COG1024	Enoyl-CoA hydratase
DTO10_22775	COG1119	ATPase activity
DTO10_22805	COG1072	(Pantothenic acid kinase))
DTO10_22815	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DTO10_22820	COG1263	PTS System
DTO10_22820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_22820	COG2190	(PTS) system
DTO10_22830	COG2890	protein-(glutamine-N5) methyltransferase activity
DTO10_22850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DTO10_22855	COG2271	Major facilitator Superfamily
DTO10_22860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DTO10_22870	COG3858	chitin binding
DTO10_22870	COG1388	LysM domain
DTO10_22890	COG0531	amino acid
DTO10_22895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DTO10_22910	COG3584	3D domain protein
DTO10_22910	COG1388	LysM domain
DTO10_22935	COG1937	Protein conserved in bacteria
DTO10_22945	COG2210	Belongs to the sulfur carrier protein TusA family
DTO10_22955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_22955	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_22960	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_22960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_22970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DTO10_22970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DTO10_22975	COG0425	Belongs to the sulfur carrier protein TusA family
DTO10_22980	COG0730	response to heat
DTO10_23010	COG1024	Enoyl-CoA hydratase
DTO10_23020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_23025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DTO10_23035	COG0583	DNA-binding transcription factor activity
DTO10_23045	COG0733	neurotransmitter:sodium symporter activity
DTO10_23055	COG0583	DNA-binding transcription factor activity
DTO10_23060	COG2610	gluconate transmembrane transporter activity
DTO10_23070	COG0577	efflux transmembrane transporter activity
DTO10_23075	COG1136	(ABC) transporter
DTO10_23090	COG5002	protein histidine kinase activity
DTO10_23095	COG0745	RESPONSE REGULATOR receiver
DTO10_23130	COG1116	anion transmembrane transporter activity
DTO10_23135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DTO10_23150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_23170	COG3361	conserved protein (COG2071)
DTO10_23175	COG0069	glutamate synthase activity
DTO10_23175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DTO10_23185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DTO10_23190	COG3689	TIGRFAM TIGR03943 family protein
DTO10_23195	COG0701	Predicted permease
DTO10_23200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_23205	COG1937	Protein conserved in bacteria
DTO10_23210	COG2608	mercury ion transmembrane transporter activity
DTO10_23215	COG2217	Heavy metal translocating P-type atpase
DTO10_23225	COG0747	negative chemotaxis
DTO10_23230	COG0601	transmembrane transport
DTO10_23235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DTO10_23240	COG0444	Belongs to the ABC transporter superfamily
DTO10_23245	COG4608	Belongs to the ABC transporter superfamily
DTO10_23260	COG3540	Alkaline phosphatase
DTO10_23265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_23270	COG0805	protein transport
DTO10_23275	COG4974	Belongs to the 'phage' integrase family
DTO10_23290	COG3378	Phage plasmid primase P4 family
DTO10_23295	COG5297	Belongs to the glycosyl hydrolase family 6
DTO10_23295	COG4733	cellulase activity
DTO10_23340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DTO10_23370	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_23415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DTO10_23455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DTO10_23480	COG0582	viral genome integration into host DNA
DTO10_23500	COG2832	Protein of unknown function (DUF454)
DTO10_23505	COG2323	membrane
DTO10_23510	COG3604	Transcriptional regulator
DTO10_23515	COG3290	protein histidine kinase activity
DTO10_23515	COG3829	transcription factor binding
DTO10_23530	COG1113	amino acid transport
DTO10_23550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_23570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DTO10_23575	COG2364	Membrane
DTO10_23580	COG2153	protein acetylation
DTO10_23585	COG1846	Transcriptional regulator
DTO10_23590	COG1132	(ABC) transporter
DTO10_23600	COG1846	Transcriptional regulator
DTO10_23610	COG0531	amino acid
DTO10_23620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_23625	COG0022	dehydrogenase e1 component
DTO10_23630	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_23645	COG0346	lactoylglutathione lyase activity
DTO10_23655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_23660	COG0697	spore germination
DTO10_23680	COG2271	Major facilitator Superfamily
DTO10_23685	COG0277	FAD linked oxidase domain protein
DTO10_23690	COG1309	transcriptional regulator
DTO10_23705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DTO10_23710	COG1228	amidohydrolase
DTO10_23720	COG2271	Major facilitator Superfamily
DTO10_23730	COG0477	Major facilitator Superfamily
DTO10_23735	COG2986	histidine ammonia-lyase
DTO10_23745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_23750	COG1914	H( )-stimulated, divalent metal cation uptake system
DTO10_23755	COG4336	lyase activity
DTO10_23760	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DTO10_23765	COG1984	allophanate hydrolase subunit 2
DTO10_23775	COG0243	molybdopterin cofactor binding
DTO10_23805	COG2223	nitrite transmembrane transporter activity
DTO10_23815	COG2197	response regulator
DTO10_23825	COG4585	Histidine kinase
DTO10_23830	COG1414	Transcriptional regulator
DTO10_23845	COG0583	DNA-binding transcription factor activity
DTO10_23865	COG0405	Gamma-glutamyltransferase
DTO10_23870	COG1960	acyl-CoA dehydrogenase activity
DTO10_23875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DTO10_23880	COG0765	amino acid transport
DTO10_23885	COG0765	amino acid transport
DTO10_23890	COG1126	abc transporter atp-binding protein
DTO10_23895	COG2135	peptidase activity
DTO10_23905	COG1115	amino acid carrier protein
DTO10_23915	COG0861	Integral membrane protein TerC family
DTO10_23930	COG1122	ATPase activity
DTO10_23945	COG0310	cobalt ion transport
DTO10_24010	COG0778	Nitroreductase
DTO10_24020	COG1492	cobalamin metabolic process
DTO10_24035	COG0515	serine threonine protein kinase
DTO10_24040	COG3878	Protein conserved in bacteria
DTO10_24060	COG1960	acyl-CoA dehydrogenase activity
DTO10_24070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DTO10_24075	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24085	COG1960	acyl-CoA dehydrogenase activity
DTO10_24090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DTO10_24095	COG4721	ABC-type cobalt transport system, permease component
DTO10_24100	COG1122	ATPase activity
DTO10_24110	COG0352	thiamine-phosphate diphosphorylase activity
DTO10_24115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_24125	COG2022	thiamine diphosphate biosynthetic process
DTO10_24130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DTO10_24150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DTO10_24155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DTO10_24175	COG0824	Thioesterase
DTO10_24185	COG4841	protein insertion into membrane
DTO10_24190	COG2816	NAD+ diphosphatase activity
DTO10_24195	COG1695	Transcriptional regulator
DTO10_24200	COG3093	addiction module antidote protein HigA
DTO10_24205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DTO10_24210	COG1832	CoA-binding protein
DTO10_24215	COG0187	DNA topoisomerase II activity
DTO10_24220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DTO10_24225	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24230	COG1960	acyl-CoA dehydrogenase activity
DTO10_24235	COG1960	acyl-CoA dehydrogenase activity
DTO10_24260	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24275	COG0559	Belongs to the binding-protein-dependent transport system permease family
DTO10_24310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DTO10_24315	COG1737	Transcriptional regulator
DTO10_24320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_24320	COG1263	PTS System
DTO10_24330	COG1472	Belongs to the glycosyl hydrolase 3 family
DTO10_24335	COG3876	Protein conserved in bacteria
DTO10_24340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DTO10_24340	COG1263	PTS System
DTO10_24350	COG0673	inositol 2-dehydrogenase activity
DTO10_24360	COG2814	Major facilitator Superfamily
DTO10_24370	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24375	COG3964	amidohydrolase
DTO10_24395	COG2188	Transcriptional regulator
DTO10_24420	COG1414	Transcriptional regulator
DTO10_24435	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24440	COG0028	Belongs to the TPP enzyme family
DTO10_24445	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_24455	COG4638	Rieske (2fe-2S)
DTO10_24465	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24475	COG1141	Ferredoxin
DTO10_24490	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24495	COG1250	3-hydroxyacyl-CoA dehydrogenase
DTO10_24505	COG3290	protein histidine kinase activity
DTO10_24505	COG3829	transcription factor binding
DTO10_24510	COG2610	gluconate transmembrane transporter activity
DTO10_24515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DTO10_24520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_24545	COG1607	acyl-coa hydrolase
DTO10_24550	COG1271	oxidase subunit
DTO10_24555	COG1294	oxidase, subunit
DTO10_24565	COG1309	transcriptional regulator
DTO10_24570	COG1960	acyl-CoA dehydrogenase activity
DTO10_24575	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24580	COG0439	Biotin carboxylase
DTO10_24585	COG0511	ligase activity, forming carbon-carbon bonds
DTO10_24590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_24595	COG1024	Enoyl-CoA hydratase
DTO10_24600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DTO10_24605	COG0494	nUDIX hydrolase
DTO10_24610	COG1335	isochorismatase
DTO10_24615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DTO10_24665	COG1876	peptidase activity
DTO10_24705	COG1714	RDD family
DTO10_24735	COG1335	isochorismatase
DTO10_24750	COG0531	amino acid
DTO10_24755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_24765	COG2814	Major facilitator Superfamily
DTO10_24775	COG2814	Major facilitator Superfamily
DTO10_24780	COG1742	UPF0060 membrane protein
DTO10_24785	COG0697	spore germination
DTO10_24800	COG2267	carboxylic ester hydrolase activity
DTO10_24810	COG2267	carboxylic ester hydrolase activity
DTO10_24815	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_24815	COG0596	Alpha beta hydrolase
DTO10_24830	COG3290	protein histidine kinase activity
DTO10_24830	COG3829	transcription factor binding
DTO10_24835	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24840	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24845	COG2271	Major facilitator Superfamily
DTO10_24860	COG3243	poly(R)-hydroxyalkanoic acid synthase
DTO10_24865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_24925	COG0583	DNA-binding transcription factor activity
DTO10_24930	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_24955	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24965	COG2271	Major facilitator Superfamily
DTO10_24975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DTO10_24980	COG0583	DNA-binding transcription factor activity
DTO10_24985	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_24995	COG0300	oxidoreductase activity
DTO10_25000	COG1960	acyl-CoA dehydrogenase activity
DTO10_25045	COG0542	response to heat
DTO10_25050	COG1523	belongs to the glycosyl hydrolase 13 family
DTO10_25070	COG4294	response to UV
DTO10_25075	COG0582	viral genome integration into host DNA
DTO10_25085	COG1802	Transcriptional regulator
DTO10_25090	COG0579	oxidoreductase
DTO10_25110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DTO10_25125	COG0069	glutamate synthase activity
DTO10_25130	COG3835	regulator
DTO10_25135	COG1929	Belongs to the glycerate kinase type-1 family
DTO10_25140	COG2610	gluconate transmembrane transporter activity
DTO10_25175	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DTO10_25190	COG3852	Histidine kinase
DTO10_25195	COG2204	response regulator
DTO10_25205	COG1840	ABC-type Fe3 transport system, periplasmic component
DTO10_25215	COG1176	ABC-type spermidine putrescine transport system, permease component I
DTO10_25220	COG1177	transmembrane transport
DTO10_25255	COG0596	Alpha beta hydrolase
DTO10_25260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DTO10_25285	COG3284	Transcriptional regulator
DTO10_25290	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_25295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_25300	COG0508	dehydrogenase complex catalyzes the overall conversion of
DTO10_25305	COG0022	dehydrogenase e1 component
DTO10_25310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DTO10_25315	COG1309	transcriptional regulator
DTO10_25325	COG2814	Major facilitator Superfamily
DTO10_25330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DTO10_25335	COG5002	protein histidine kinase activity
DTO10_25340	COG1960	acyl-CoA dehydrogenase activity
DTO10_25345	COG1160	GTP binding
DTO10_25355	COG0024	Methionine aminopeptidase
DTO10_25375	COG1309	transcriptional regulator
DTO10_25430	COG2207	Transcriptional regulator
DTO10_25430	COG1917	Cupin 2, conserved barrel domain protein
DTO10_25435	COG0697	spore germination
DTO10_25440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DTO10_25445	COG1028	Short-chain dehydrogenase reductase Sdr
DTO10_25450	COG1070	Carbohydrate kinase
DTO10_25455	COG3775	system Galactitol-specific IIC component
DTO10_25465	COG1830	Aldolase
DTO10_25475	COG1301	dicarboxylic acid transport
DTO10_25480	COG0028	Belongs to the TPP enzyme family
DTO10_25485	COG0436	Aminotransferase
DTO10_25500	COG1414	Transcriptional regulator
DTO10_25505	COG1011	Hydrolase
DTO10_25530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DTO10_25535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DTO10_25550	COG0668	transmembrane transport
DTO10_25570	COG2234	aminopeptidase activity
DTO10_25635	COG2234	aminopeptidase activity
DTO10_25655	COG2271	Major facilitator Superfamily
DTO10_25660	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_25670	COG0583	DNA-binding transcription factor activity
DTO10_25675	COG4191	Histidine kinase
DTO10_25680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DTO10_25685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DTO10_25690	COG0583	DNA-binding transcription factor activity
DTO10_25695	COG0741	lytic transglycosylase activity
DTO10_25740	COG2301	Belongs to the HpcH HpaI aldolase family
DTO10_25750	COG2851	Citrate transporter
DTO10_25755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DTO10_25760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DTO10_25765	COG1802	Transcriptional regulator
DTO10_25770	COG1473	amidohydrolase
DTO10_25775	COG1288	antiporter activity
DTO10_25790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DTO10_25805	COG4608	Belongs to the ABC transporter superfamily
DTO10_25810	COG0444	Belongs to the ABC transporter superfamily
DTO10_25820	COG0601	transmembrane transport
DTO10_25840	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_25845	COG0473	3-isopropylmalate dehydrogenase activity
DTO10_25850	COG3829	transcription factor binding
DTO10_25850	COG3290	protein histidine kinase activity
DTO10_25880	COG2205	protein histidine kinase activity
DTO10_25890	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DTO10_25895	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DTO10_25905	COG5609	conserved protein (DUF2294)
DTO10_25915	COG3409	Peptidoglycan-binding domain 1 protein
DTO10_25915	COG3773	Cell wall hydrolase
DTO10_25925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DTO10_25955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DTO10_25970	COG3540	Alkaline phosphatase
DTO10_25975	COG3540	Alkaline phosphatase
DTO10_25980	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_26010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DTO10_26060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DTO10_26070	COG3344	reverse transcriptase
DTO10_26090	COG0584	glycerophosphoryl diester phosphodiesterase
DTO10_26135	COG1164	Oligoendopeptidase f
DTO10_26150	COG0788	formyltetrahydrofolate deformylase activity
DTO10_26155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DTO10_26165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DTO10_26170	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_26175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DTO10_26180	COG0509	glycine decarboxylation via glycine cleavage system
DTO10_26190	COG1760	l-serine dehydratase
DTO10_26195	COG1760	l-serine dehydratase
DTO10_26205	COG1113	amino acid transport
DTO10_26210	COG2076	Multidrug Resistance protein
DTO10_26215	COG2076	Multidrug Resistance protein
DTO10_26220	COG0561	phosphatase activity
DTO10_26225	COG1349	DNA-binding transcription factor activity
DTO10_26280	COG0531	amino acid
DTO10_26285	COG0789	Transcriptional regulator
DTO10_26285	COG4978	Transcriptional regulator
DTO10_26405	COG1695	Transcriptional regulator
DTO10_26410	COG2132	Multicopper oxidase
DTO10_26445	COG0656	L-ascorbic acid biosynthetic process
DTO10_26450	COG0789	Transcriptional regulator
DTO10_26490	COG0590	tRNA wobble adenosine to inosine editing
DTO10_26520	COG2329	Antibiotic biosynthesis monooxygenase
DTO10_26525	COG0024	Methionine aminopeptidase
DTO10_26530	COG2808	Putative FMN-binding domain
DTO10_26535	COG0456	acetyltransferase
DTO10_26540	COG1846	Transcriptional regulator
DTO10_26560	COG2843	Capsule synthesis protein
DTO10_26615	COG0179	Fumarylacetoacetate (FAA) hydrolase
DTO10_26625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DTO10_26655	COG3858	chitin binding
DTO10_26680	COG0318	PFAM AMP-dependent synthetase and ligase
DTO10_26685	COG1957	nucleoside hydrolase
DTO10_26690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DTO10_26700	COG1522	sequence-specific DNA binding
DTO10_26700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_26710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DTO10_26720	COG1012	belongs to the aldehyde dehydrogenase family
DTO10_26725	COG1960	acyl-CoA dehydrogenase activity
DTO10_26730	COG1960	acyl-CoA dehydrogenase activity
DTO10_26750	COG2030	dehydratase
DTO10_26755	COG0045	succinate-CoA ligase (ADP-forming) activity
DTO10_26755	COG1042	CoA-binding domain protein
DTO10_26755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins