locus-tag	class	description
Bcell_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Bcell_0002	COG0592	DNA-directed DNA polymerase activity
Bcell_0003	COG2501	S4 domain
Bcell_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Bcell_0006	COG0187	DNA topoisomerase II activity
Bcell_0007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bcell_0008	COG0753	catalase activity
Bcell_0011	COG0516	GMP reductase activity
Bcell_0011	COG0517	IMP dehydrogenase activity
Bcell_0013	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Bcell_0014	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Bcell_0015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Bcell_0016	COG0444	Belongs to the ABC transporter superfamily
Bcell_0017	COG4608	Belongs to the ABC transporter superfamily
Bcell_0018	COG0747	negative chemotaxis
Bcell_0019	COG0601	transmembrane transport
Bcell_0020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bcell_0023	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Bcell_0024	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Bcell_0025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Bcell_0029	COG1982	Orn Lys Arg decarboxylase major
Bcell_0030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Bcell_0031	COG3870	Protein conserved in bacteria
Bcell_0032	COG0470	DNA polymerase III
Bcell_0033	COG1774	PSP1 C-terminal conserved region
Bcell_0035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Bcell_0036	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Bcell_0037	COG2002	toxin-antitoxin pair type II binding
Bcell_0038	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcell_0038	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcell_0039	COG0084	hydrolase, TatD family'
Bcell_0040	COG3583	domain protein
Bcell_0040	COG3584	3D domain protein
Bcell_0041	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Bcell_0042	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Bcell_0044	COG4466	Protein conserved in bacteria
Bcell_0046	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Bcell_0047	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bcell_0048	COG2088	sporulation resulting in formation of a cellular spore
Bcell_0050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bcell_0052	COG0193	aminoacyl-tRNA hydrolase activity
Bcell_0054	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bcell_0055	COG2002	toxin-antitoxin pair type II binding
Bcell_0056	COG2244	polysaccharide biosynthetic process
Bcell_0057	COG3956	TIGRFAM MazG family protein
Bcell_0058	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Bcell_0062	COG1098	S1 RNA binding domain
Bcell_0063	COG2208	phosphoserine phosphatase activity
Bcell_0064	COG2304	oxidoreductase activity
Bcell_0065	COG0515	serine threonine protein kinase
Bcell_0066	COG2966	Psort location CytoplasmicMembrane, score
Bcell_0068	COG0037	tRNA processing
Bcell_0072	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Bcell_0073	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bcell_0074	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Bcell_0075	COG0512	Glutamine amidotransferase of anthranilate synthase
Bcell_0076	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bcell_0077	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Bcell_0078	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Bcell_0079	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Bcell_0080	COG1396	sequence-specific DNA binding
Bcell_0081	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bcell_0082	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Bcell_0083	COG1285	pathogenesis
Bcell_0085	COG3880	PFAM UvrB UvrC protein
Bcell_0086	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Bcell_0087	COG0542	response to heat
Bcell_0088	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Bcell_0089	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Bcell_0090	COG4956	integral membrane protein (PIN domain superfamily)
Bcell_0091	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Bcell_0093	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Bcell_0094	COG1045	serine acetyltransferase
Bcell_0095	COG0215	cysteine-tRNA ligase activity
Bcell_0097	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bcell_0098	COG3688	RNA-binding protein containing a PIN domain
Bcell_0100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bcell_0101	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bcell_0102	COG0250	Participates in transcription elongation, termination and antitermination
Bcell_0103	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Bcell_0104	COG0081	regulation of translation
Bcell_0106	COG0222	ribosome binding
Bcell_0107	COG2813	Specifically methylates the guanine in position
Bcell_0108	COG0085	RNA polymerase activity
Bcell_0109	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Bcell_0110	COG1358	cellular component organization or biogenesis
Bcell_0111	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Bcell_0112	COG0049	tRNA binding
Bcell_0113	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Bcell_0114	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Bcell_0117	COG4608	Belongs to the ABC transporter superfamily
Bcell_0118	COG0601	transmembrane transport
Bcell_0120	COG4166	transmembrane transport
Bcell_0121	COG0051	transcription antitermination factor activity, RNA binding
Bcell_0122	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Bcell_0123	COG0088	Forms part of the polypeptide exit tunnel
Bcell_0124	COG0089	rRNA binding
Bcell_0125	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Bcell_0126	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Bcell_0127	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Bcell_0128	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Bcell_0129	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Bcell_0130	COG0255	Belongs to the universal ribosomal protein uL29 family
Bcell_0131	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Bcell_0132	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Bcell_0133	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Bcell_0134	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Bcell_0135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Bcell_0136	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Bcell_0137	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Bcell_0138	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Bcell_0139	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Bcell_0140	COG1841	ribosomal large subunit assembly
Bcell_0141	COG0200	Binds to the 23S rRNA
Bcell_0142	COG0201	protein transport
Bcell_0143	COG0563	adenylate kinase activity
Bcell_0144	COG0024	Methionine aminopeptidase
Bcell_0146	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Bcell_0147	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Bcell_0148	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Bcell_0149	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Bcell_0150	COG0202	RNA polymerase activity
Bcell_0151	COG0203	ribosomal protein L17
Bcell_0154	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bcell_0155	COG0101	tRNA pseudouridine synthase activity
Bcell_0156	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Bcell_0157	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Bcell_0161	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcell_0162	COG0489	protein tyrosine kinase activity
Bcell_0164	COG2194	sulfuric ester hydrolase activity
Bcell_0165	COG0726	polysaccharide deacetylase
Bcell_0168	COG1595	DNA-templated transcription, initiation
Bcell_0169	COG5662	AntiSigma factor
Bcell_0170	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Bcell_0171	COG4856	YbbR-like protein
Bcell_0172	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bcell_0173	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Bcell_0182	COG1793	dna ligase
Bcell_0185	COG0385	Bile acid
Bcell_0214	COG0582	viral genome integration into host DNA
Bcell_0238	COG1131	(ABC) transporter
Bcell_0245	COG0583	DNA-binding transcription factor activity
Bcell_0247	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bcell_0248	COG2146	nitrite reductase [NAD(P)H] activity
Bcell_0249	COG1587	Uroporphyrinogen-III synthase
Bcell_0249	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Bcell_0250	COG2197	response regulator
Bcell_0251	COG4988	ABC transporter
Bcell_0252	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bcell_0255	COG1294	oxidase, subunit
Bcell_0256	COG1271	oxidase subunit
Bcell_0258	COG1595	DNA-templated transcription, initiation
Bcell_0259	COG0010	Belongs to the arginase family
Bcell_0262	COG5002	protein histidine kinase activity
Bcell_0263	COG0745	RESPONSE REGULATOR receiver
Bcell_0265	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bcell_0266	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcell_0267	COG0386	Belongs to the glutathione peroxidase family
Bcell_0269	COG5577	PFAM Coat F domain
Bcell_0271	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Bcell_0272	COG0640	Transcriptional regulator
Bcell_0273	COG0798	PFAM Bile acid sodium symporter
Bcell_0274	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bcell_0276	COG0798	PFAM Bile acid sodium symporter
Bcell_0277	COG2942	2-epimerase
Bcell_0278	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Bcell_0280	COG3546	catalase activity
Bcell_0284	COG0783	Belongs to the Dps family
Bcell_0286	COG1940	carbohydrate kinase activity
Bcell_0291	COG0589	response to stress
Bcell_0292	COG0659	secondary active sulfate transmembrane transporter activity
Bcell_0297	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcell_0298	COG1278	Cold shock
Bcell_0300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Bcell_0301	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Bcell_0304	COG0681	Belongs to the peptidase S26 family
Bcell_0306	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bcell_0307	COG0431	NADPH-dependent FMN reductase
Bcell_0308	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcell_0311	COG0018	arginyl-trna synthetase
Bcell_0312	COG0425	Belongs to the sulfur carrier protein TusA family
Bcell_0312	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_0314	COG1937	Protein conserved in bacteria
Bcell_0325	COG1510	regulation of RNA biosynthetic process
Bcell_0326	COG1595	DNA-templated transcription, initiation
Bcell_0328	COG2239	Acts as a magnesium transporter
Bcell_0329	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bcell_0330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Bcell_0332	COG3842	ATPase activity
Bcell_0335	COG0705	Rhomboid family
Bcell_0336	COG0736	holo-[acyl-carrier-protein] synthase activity
Bcell_0337	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Bcell_0337	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Bcell_0338	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Bcell_0339	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bcell_0340	COG0864	Transcriptional regulator
Bcell_0341	COG2337	Toxic component of a toxin-antitoxin (TA) module
Bcell_0342	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcell_0343	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcell_0344	COG2172	sigma factor antagonist activity
Bcell_0345	COG2208	phosphoserine phosphatase activity
Bcell_0346	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcell_0347	COG2172	sigma factor antagonist activity
Bcell_0348	COG1191	sigma factor activity
Bcell_0349	COG2208	phosphoserine phosphatase activity
Bcell_0350	COG2183	response to ionizing radiation
Bcell_0352	COG3091	SprT-like family
Bcell_0354	COG0840	transmembrane signaling receptor activity
Bcell_0355	COG0626	cystathionine gamma-synthase activity
Bcell_0356	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Bcell_0357	COG0802	atpase or kinase
Bcell_0358	COG1214	PFAM Peptidase M22, glycoprotease
Bcell_0359	COG0456	acetyltransferase
Bcell_0362	COG0488	(ABC) transporter
Bcell_0363	COG0315	cyclic pyranopterin monophosphate synthase activity
Bcell_0364	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Bcell_0365	COG2814	Major facilitator Superfamily
Bcell_0368	COG1266	CAAX protease self-immunity
Bcell_0369	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Bcell_0370	COG0459	protein refolding
Bcell_0373	COG0673	inositol 2-dehydrogenase activity
Bcell_0375	COG0673	inositol 2-dehydrogenase activity
Bcell_0376	COG1129	ABC transporter
Bcell_0377	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bcell_0378	COG1082	Xylose isomerase domain protein TIM barrel
Bcell_0379	COG1609	Transcriptional regulator
Bcell_0382	COG1309	transcriptional regulator
Bcell_0387	COG1714	RDD family
Bcell_0390	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bcell_0391	COG4605	iron ion homeostasis
Bcell_0392	COG4604	ABC transporter, ATP-binding protein
Bcell_0393	COG4607	ABC-type enterochelin transport system periplasmic component
Bcell_0394	COG2329	Antibiotic biosynthesis monooxygenase
Bcell_0399	COG0840	transmembrane signaling receptor activity
Bcell_0400	COG0714	Associated with various cellular activities
Bcell_0401	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Bcell_0402	COG1305	Transglutaminase-like
Bcell_0403	COG0519	Catalyzes the synthesis of GMP from XMP
Bcell_0403	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Bcell_0404	COG2252	PERMEase
Bcell_0406	COG3424	synthase
Bcell_0407	COG1755	Isoprenylcysteine carboxyl methyltransferase
Bcell_0409	COG5577	PFAM Coat F domain
Bcell_0412	COG0154	amidase activity
Bcell_0413	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Bcell_0414	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Bcell_0415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bcell_0416	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Bcell_0417	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bcell_0418	COG0047	phosphoribosylformylglycinamidine synthase activity
Bcell_0419	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bcell_0420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Bcell_0422	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Bcell_0424	COG0151	Belongs to the GarS family
Bcell_0427	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Bcell_0428	COG1470	cell adhesion involved in biofilm formation
Bcell_0429	COG4496	protein, YerC YecD
Bcell_0430	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Bcell_0431	COG0210	DNA helicase
Bcell_0432	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Bcell_0433	COG4851	CamS sex pheromone cAM373 precursor
Bcell_0434	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bcell_0435	COG0154	amidase activity
Bcell_0436	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bcell_0437	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Bcell_0438	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Bcell_0439	COG1834	amidinotransferase
Bcell_0441	COG1597	lipid kinase activity
Bcell_0443	COG1131	(ABC) transporter
Bcell_0444	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bcell_0447	COG2311	Membrane
Bcell_0452	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_0453	COG1403	HNH endonuclease
Bcell_0461	COG1405	negative regulation of cell septum assembly
Bcell_0461	COG3012	SEC-C Motif Domain Protein
Bcell_0462	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bcell_0466	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bcell_0468	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Bcell_0469	COG4213	ABC transporter substrate-binding protein
Bcell_0470	COG1129	ABC transporter
Bcell_0471	COG4214	carbohydrate transport
Bcell_0473	COG2972	Histidine kinase
Bcell_0474	COG2207	Transcriptional regulator
Bcell_0474	COG4753	response regulator
Bcell_0475	COG4213	ABC transporter substrate-binding protein
Bcell_0477	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Bcell_0478	COG3459	Glycosyltransferase 36 associated
Bcell_0480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Bcell_0482	COG0673	inositol 2-dehydrogenase activity
Bcell_0487	COG0673	inositol 2-dehydrogenase activity
Bcell_0488	COG1082	Xylose isomerase domain protein TIM barrel
Bcell_0490	COG1609	Transcriptional regulator
Bcell_0491	COG0366	Alpha amylase catalytic
Bcell_0492	COG2323	membrane
Bcell_0494	COG1846	Transcriptional regulator
Bcell_0495	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bcell_0496	COG0346	lactoylglutathione lyase activity
Bcell_0501	COG1164	Oligoendopeptidase f
Bcell_0504	COG1136	(ABC) transporter
Bcell_0504	COG0577	efflux transmembrane transporter activity
Bcell_0505	COG0577	efflux transmembrane transporter activity
Bcell_0505	COG1136	(ABC) transporter
Bcell_0506	COG3850	Histidine kinase
Bcell_0506	COG5002	protein histidine kinase activity
Bcell_0510	COG0789	Transcriptional regulator
Bcell_0511	COG1376	ErfK ybiS ycfS ynhG family protein
Bcell_0513	COG0737	Belongs to the 5'-nucleotidase family
Bcell_0514	COG0673	inositol 2-dehydrogenase activity
Bcell_0516	COG0133	tryptophan synthase activity
Bcell_0518	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bcell_0520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Bcell_0522	COG1136	(ABC) transporter
Bcell_0528	COG0501	Belongs to the peptidase M48B family
Bcell_0529	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Bcell_0530	COG4585	Histidine kinase
Bcell_0531	COG2197	response regulator
Bcell_0535	COG2814	Major facilitator Superfamily
Bcell_0536	COG1132	(ABC) transporter
Bcell_0537	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Bcell_0540	COG5578	integral membrane protein
Bcell_0542	COG4753	response regulator
Bcell_0542	COG2207	Transcriptional regulator
Bcell_0542	COG4753	response regulator
Bcell_0542	COG2207	Transcriptional regulator
Bcell_0543	COG2972	Histidine kinase
Bcell_0545	COG4209	transmembrane transport
Bcell_0546	COG0395	ABC-type sugar transport system, permease component
Bcell_0549	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_0550	COG1904	glucuronate isomerase
Bcell_0552	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Bcell_0554	COG3507	Belongs to the glycosyl hydrolase 43 family
Bcell_0557	COG1175	transmembrane transport
Bcell_0559	COG5578	integral membrane protein
Bcell_0560	COG1070	Carbohydrate kinase
Bcell_0562	COG4191	Histidine kinase
Bcell_0564	COG0561	phosphatase activity
Bcell_0568	COG1295	ribonuclease BN
Bcell_0570	COG4989	oxidoreductase activity
Bcell_0573	COG0471	metal ion transport
Bcell_0573	COG0490	domain, Protein
Bcell_0578	COG0667	Aldo Keto reductase
Bcell_0584	COG0129	dihydroxy-acid dehydratase activity
Bcell_0585	COG0662	Cupin 2, conserved barrel domain protein
Bcell_0589	COG1078	dGTPase activity
Bcell_0590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Bcell_0592	COG1408	metallophosphoesterase
Bcell_0594	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bcell_0595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bcell_0596	COG5002	protein histidine kinase activity
Bcell_0597	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bcell_0605	COG0588	phosphoglycerate mutase activity
Bcell_0609	COG0346	lactoylglutathione lyase activity
Bcell_0614	COG0745	RESPONSE REGULATOR receiver
Bcell_0615	COG2205	protein histidine kinase activity
Bcell_0616	COG1136	(ABC) transporter
Bcell_0617	COG0577	efflux transmembrane transporter activity
Bcell_0619	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bcell_0621	COG3534	alpha-L-arabinofuranosidase
Bcell_0623	COG2885	chlorophyll binding
Bcell_0623	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Bcell_0625	COG3397	chitin binding
Bcell_0627	COG0697	spore germination
Bcell_0633	COG4555	ABC transporter
Bcell_0638	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bcell_0642	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bcell_0644	COG1278	Cold shock
Bcell_0649	COG0584	glycerophosphoryl diester phosphodiesterase
Bcell_0651	COG3764	Sortase (surface protein transpeptidase)
Bcell_0653	COG0501	Belongs to the peptidase M48B family
Bcell_0655	COG0456	acetyltransferase
Bcell_0661	COG0840	transmembrane signaling receptor activity
Bcell_0661	COG3290	protein histidine kinase activity
Bcell_0663	COG4221	oxidoreductase activity
Bcell_0665	COG0840	transmembrane signaling receptor activity
Bcell_0667	COG1175	transmembrane transport
Bcell_0668	COG0395	ABC-type sugar transport system, permease component
Bcell_0669	COG1609	Transcriptional regulator
Bcell_0671	COG1175	transmembrane transport
Bcell_0672	COG0395	ABC-type sugar transport system, permease component
Bcell_0675	COG1175	transmembrane transport
Bcell_0676	COG0395	ABC-type sugar transport system, permease component
Bcell_0679	COG1175	transmembrane transport
Bcell_0680	COG0395	ABC-type sugar transport system, permease component
Bcell_0681	COG5578	integral membrane protein
Bcell_0684	COG3250	beta-galactosidase activity
Bcell_0688	COG0395	ABC-type sugar transport system, permease component
Bcell_0689	COG5520	Belongs to the glycosyl hydrolase 30 family
Bcell_0693	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Bcell_0694	COG2154	pterin-4-alpha-carbinolamine dehydratase
Bcell_0695	COG0435	Glutathione S-transferase
Bcell_0698	COG4585	Histidine kinase
Bcell_0699	COG2197	response regulator
Bcell_0700	COG1131	(ABC) transporter
Bcell_0703	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_0704	COG2207	Transcriptional regulator
Bcell_0706	COG3328	transposase activity
Bcell_0707	COG1666	GTP binding
Bcell_0709	COG0492	ferredoxin-NADP+ reductase activity
Bcell_0710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Bcell_0714	COG0406	alpha-ribazole phosphatase activity
Bcell_0715	COG0326	Molecular chaperone. Has ATPase activity
Bcell_0719	COG1309	transcriptional regulator
Bcell_0724	COG1988	membrane-bound metal-dependent
Bcell_0727	COG1073	alpha beta
Bcell_0728	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bcell_0730	COG0402	S-adenosylhomocysteine deaminase activity
Bcell_0731	COG1132	(ABC) transporter
Bcell_0732	COG1132	(ABC) transporter
Bcell_0733	COG0387	Pfam Sodium calcium exchanger
Bcell_0734	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcell_0737	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Bcell_0738	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Bcell_0740	COG0514	ATP-dependent DNA helicase (RecQ)
Bcell_0741	COG5002	protein histidine kinase activity
Bcell_0741	COG2198	Histidine kinase
Bcell_0741	COG0784	Response regulator, receiver
Bcell_0742	COG0745	RESPONSE REGULATOR receiver
Bcell_0744	COG0840	transmembrane signaling receptor activity
Bcell_0745	COG0400	carboxylic ester hydrolase activity
Bcell_0746	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bcell_0747	COG0488	(ABC) transporter
Bcell_0752	COG0714	Associated with various cellular activities
Bcell_0755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bcell_0756	COG0513	Belongs to the DEAD box helicase family
Bcell_0758	COG0352	thiamine-phosphate diphosphorylase activity
Bcell_0759	COG0351	phosphomethylpyrimidine kinase
Bcell_0760	COG2022	thiamine diphosphate biosynthetic process
Bcell_0762	COG0352	thiamine-phosphate diphosphorylase activity
Bcell_0764	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bcell_0766	COG0488	(ABC) transporter
Bcell_0768	COG0628	permease
Bcell_0769	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bcell_0769	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bcell_0770	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bcell_0772	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Bcell_0773	COG2153	protein acetylation
Bcell_0774	COG1077	Cell shape determining protein MreB Mrl
Bcell_0775	COG1960	acyl-CoA dehydrogenase activity
Bcell_0776	COG2258	MOSC domain
Bcell_0780	COG1834	amidinotransferase
Bcell_0781	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bcell_0783	COG0534	Mate efflux family protein
Bcell_0784	COG1012	belongs to the aldehyde dehydrogenase family
Bcell_0787	COG1254	Belongs to the acylphosphatase family
Bcell_0791	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_0795	COG0477	Major facilitator Superfamily
Bcell_0797	COG0534	Mate efflux family protein
Bcell_0801	COG0535	radical SAM domain protein
Bcell_0803	COG0778	Nitroreductase
Bcell_0807	COG0167	dihydroorotate dehydrogenase activity
Bcell_0812	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bcell_0813	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bcell_0815	COG1309	transcriptional regulator
Bcell_0826	COG0840	transmembrane signaling receptor activity
Bcell_0827	COG0840	transmembrane signaling receptor activity
Bcell_0830	COG0523	cobalamin synthesis protein
Bcell_0832	COG0701	Predicted permease
Bcell_0834	COG0822	iron-sulfur transferase activity
Bcell_0837	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bcell_0839	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bcell_0841	COG1263	PTS System
Bcell_0841	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcell_0842	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Bcell_0847	COG4191	Histidine kinase
Bcell_0849	COG0386	Belongs to the glutathione peroxidase family
Bcell_0850	COG4443	Transcriptional Coactivator p15 (PC4)
Bcell_0851	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Bcell_0852	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bcell_0854	COG1335	isochorismatase
Bcell_0856	COG1595	DNA-templated transcription, initiation
Bcell_0859	COG0534	Mate efflux family protein
Bcell_0860	COG0456	acetyltransferase
Bcell_0861	COG1183	phosphatidylcholine synthase activity
Bcell_0863	COG0166	Belongs to the GPI family
Bcell_0865	COG0527	aspartate kinase activity
Bcell_0867	COG1476	TRANSCRIPTIONal
Bcell_0869	COG1132	(ABC) transporter
Bcell_0871	COG2223	nitrite transmembrane transporter activity
Bcell_0873	COG2146	nitrite reductase [NAD(P)H] activity
Bcell_0874	COG0243	molybdopterin cofactor binding
Bcell_0875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bcell_0878	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Bcell_0878	COG1648	precorrin-2 dehydrogenase activity
Bcell_0880	COG3069	C4-dicarboxylate transmembrane transporter activity
Bcell_0881	COG2094	Belongs to the DNA glycosylase MPG family
Bcell_0884	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Bcell_0885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Bcell_0887	COG2508	Transcriptional regulator
Bcell_0888	COG0154	amidase activity
Bcell_0893	COG2205	protein histidine kinase activity
Bcell_0894	COG0733	neurotransmitter:sodium symporter activity
Bcell_0897	COG1216	Glycosyl transferase, family 2
Bcell_0902	COG0791	NLP P60 protein
Bcell_0902	COG1388	LysM domain
Bcell_0908	COG0789	Transcriptional regulator
Bcell_0914	COG1122	ATPase activity
Bcell_0919	COG3830	Belongs to the UPF0237 family
Bcell_0921	COG0366	Alpha amylase catalytic
Bcell_0922	COG2188	Transcriptional regulator
Bcell_0934	COG1335	isochorismatase
Bcell_0940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Bcell_0944	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_0946	COG1595	DNA-templated transcription, initiation
Bcell_0952	COG1595	DNA-templated transcription, initiation
Bcell_0961	COG1090	epimerase
Bcell_0962	COG2137	regulation of response to DNA damage stimulus
Bcell_0966	COG1988	membrane-bound metal-dependent
Bcell_0968	COG1194	a g-specific adenine glycosylase
Bcell_0969	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_0974	COG2059	Chromate
Bcell_0975	COG2059	Chromate
Bcell_0978	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_0982	COG3557	Belongs to the UPF0374 family
Bcell_0983	COG1132	(ABC) transporter
Bcell_0984	COG4129	membrane
Bcell_0985	COG0067	glutamate synthase
Bcell_0985	COG0070	glutamate synthase
Bcell_0985	COG0069	glutamate synthase activity
Bcell_0986	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bcell_0987	COG4555	ABC transporter
Bcell_0991	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Bcell_0992	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bcell_0993	COG1131	(ABC) transporter
Bcell_0995	COG3870	Protein conserved in bacteria
Bcell_0996	COG0735	belongs to the Fur family
Bcell_1000	COG1595	DNA-templated transcription, initiation
Bcell_1002	COG3708	Transcriptional regulator
Bcell_1002	COG2207	Transcriptional regulator
Bcell_1006	COG3842	ATPase activity
Bcell_1007	COG1175	transmembrane transport
Bcell_1012	COG0745	RESPONSE REGULATOR receiver
Bcell_1012	COG3706	GGDEF domain
Bcell_1015	COG2226	methyltransferase
Bcell_1018	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Bcell_1022	COG0456	acetyltransferase
Bcell_1025	COG2801	Transposase and inactivated derivatives
Bcell_1027	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bcell_1028	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bcell_1030	COG1695	Transcriptional regulator
Bcell_1032	COG1940	carbohydrate kinase activity
Bcell_1034	COG1940	carbohydrate kinase activity
Bcell_1036	COG0395	ABC-type sugar transport system, permease component
Bcell_1037	COG1175	transmembrane transport
Bcell_1043	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Bcell_1044	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bcell_1045	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Bcell_1046	COG1940	carbohydrate kinase activity
Bcell_1057	COG3813	Protein conserved in bacteria
Bcell_1059	COG4533	DNA binding
Bcell_1068	COG2311	Membrane
Bcell_1072	COG1595	DNA-templated transcription, initiation
Bcell_1075	COG0697	spore germination
Bcell_1076	COG2203	Gaf domain
Bcell_1076	COG2199	diguanylate cyclase activity
Bcell_1078	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Bcell_1090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Bcell_1091	COG0402	S-adenosylhomocysteine deaminase activity
Bcell_1094	COG0488	(ABC) transporter
Bcell_1097	COG1175	transmembrane transport
Bcell_1098	COG0395	ABC-type sugar transport system, permease component
Bcell_1100	COG2207	Transcriptional regulator
Bcell_1103	COG3345	alpha-galactosidase
Bcell_1105	COG2207	Transcriptional regulator
Bcell_1105	COG3708	Transcriptional regulator
Bcell_1107	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_1111	COG5578	integral membrane protein
Bcell_1112	COG0395	ABC-type sugar transport system, permease component
Bcell_1113	COG1175	transmembrane transport
Bcell_1114	COG1653	transport
Bcell_1125	COG0582	viral genome integration into host DNA
Bcell_1150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bcell_1151	COG3973	AAA domain
Bcell_1156	COG1404	Belongs to the peptidase S8 family
Bcell_1162	COG1122	ATPase activity
Bcell_1168	COG0739	heme binding
Bcell_1178	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Bcell_1184	COG2205	protein histidine kinase activity
Bcell_1186	COG3832	glyoxalase III activity
Bcell_1188	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bcell_1196	COG2972	Histidine kinase
Bcell_1197	COG4753	response regulator
Bcell_1197	COG2207	Transcriptional regulator
Bcell_1199	COG4209	transmembrane transport
Bcell_1200	COG0395	ABC-type sugar transport system, permease component
Bcell_1202	COG1501	Belongs to the glycosyl hydrolase 31 family
Bcell_1203	COG1653	transport
Bcell_1204	COG5578	integral membrane protein
Bcell_1205	COG0840	transmembrane signaling receptor activity
Bcell_1205	COG3290	protein histidine kinase activity
Bcell_1206	COG1966	Carbon starvation protein
Bcell_1208	COG4213	ABC transporter substrate-binding protein
Bcell_1210	COG4214	carbohydrate transport
Bcell_1212	COG1069	ribulokinase activity
Bcell_1214	COG1609	Transcriptional regulator
Bcell_1215	COG1595	DNA-templated transcription, initiation
Bcell_1217	COG1131	(ABC) transporter
Bcell_1227	COG1720	tRNA m6t6A37 methyltransferase activity
Bcell_1235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcell_1237	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcell_1238	COG1335	isochorismatase
Bcell_1239	COG2508	Transcriptional regulator
Bcell_1240	COG0154	amidase activity
Bcell_1241	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bcell_1242	COG0405	Gamma-glutamyltransferase
Bcell_1243	COG2059	Chromate
Bcell_1244	COG2059	Chromate
Bcell_1250	COG2801	Transposase and inactivated derivatives
Bcell_1263	COG2318	DinB family
Bcell_1264	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bcell_1268	COG2885	chlorophyll binding
Bcell_1269	COG2323	membrane
Bcell_1272	COG1595	DNA-templated transcription, initiation
Bcell_1274	COG2814	Major facilitator Superfamily
Bcell_1281	COG0653	protein targeting
Bcell_1283	COG2323	membrane
Bcell_1286	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bcell_1294	COG1131	(ABC) transporter
Bcell_1297	COG4585	Histidine kinase
Bcell_1298	COG2197	response regulator
Bcell_1302	COG1132	(ABC) transporter
Bcell_1306	COG4946	Tricorn protease homolog
Bcell_1306	COG0823	Involved in the tonB-independent uptake of proteins
Bcell_1306	COG1506	peptidase
Bcell_1308	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcell_1309	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcell_1310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcell_1313	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Bcell_1313	COG0167	dihydroorotate dehydrogenase activity
Bcell_1316	COG2508	Transcriptional regulator
Bcell_1317	COG1012	belongs to the aldehyde dehydrogenase family
Bcell_1318	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bcell_1319	COG0840	transmembrane signaling receptor activity
Bcell_1320	COG2514	catechol 2,3-dioxygenase activity
Bcell_1322	COG0288	reversible hydration of carbon dioxide
Bcell_1323	COG2210	Belongs to the sulfur carrier protein TusA family
Bcell_1324	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_1325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_1325	COG0425	Belongs to the sulfur carrier protein TusA family
Bcell_1326	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_1326	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_1327	COG0425	Belongs to the sulfur carrier protein TusA family
Bcell_1328	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bcell_1330	COG0785	Cytochrome C biogenesis protein
Bcell_1331	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcell_1333	COG2205	protein histidine kinase activity
Bcell_1336	COG0521	Mo-molybdopterin cofactor biosynthetic process
Bcell_1337	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bcell_1339	COG1609	Transcriptional regulator
Bcell_1342	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Bcell_1343	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Bcell_1345	COG1012	belongs to the aldehyde dehydrogenase family
Bcell_1346	COG1653	transport
Bcell_1347	COG1175	transmembrane transport
Bcell_1348	COG0395	ABC-type sugar transport system, permease component
Bcell_1349	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bcell_1350	COG1929	Belongs to the glycerate kinase type-1 family
Bcell_1351	COG5578	integral membrane protein
Bcell_1352	COG2755	lipolytic protein G-D-S-L family
Bcell_1353	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_1355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bcell_1357	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Bcell_1358	COG3344	reverse transcriptase
Bcell_1362	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcell_1363	COG2766	serine protein kinase
Bcell_1365	COG2718	Belongs to the UPF0229 family
Bcell_1367	COG3973	AAA domain
Bcell_1369	COG1609	Transcriptional regulator
Bcell_1370	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Bcell_1375	COG0393	Putative heavy-metal-binding
Bcell_1376	COG3546	catalase activity
Bcell_1379	COG2201	protein-glutamate methylesterase activity
Bcell_1382	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bcell_1382	COG3153	acetyltransferase
Bcell_1385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Bcell_1387	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_1388	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Bcell_1391	COG0066	3-isopropylmalate dehydratase activity
Bcell_1392	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Bcell_1393	COG0473	3-isopropylmalate dehydrogenase activity
Bcell_1394	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bcell_1395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Bcell_1396	COG0440	acetolactate synthase activity
Bcell_1397	COG0028	Belongs to the TPP enzyme family
Bcell_1398	COG0129	dihydroxy-acid dehydratase activity
Bcell_1400	COG2719	SpoVR family
Bcell_1403	COG1227	inorganic diphosphatase activity
Bcell_1404	COG1272	protein, Hemolysin III
Bcell_1408	COG3263	regulation of cellular component size
Bcell_1410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bcell_1411	COG1368	sulfuric ester hydrolase activity
Bcell_1412	COG0024	Methionine aminopeptidase
Bcell_1413	COG1620	l-lactate permease
Bcell_1416	COG1533	DNA photolyase activity
Bcell_1421	COG1131	(ABC) transporter
Bcell_1422	COG1725	Transcriptional regulator
Bcell_1426	COG1595	DNA-templated transcription, initiation
Bcell_1428	COG1132	(ABC) transporter
Bcell_1429	COG1132	(ABC) transporter
Bcell_1431	COG1215	transferase activity, transferring glycosyl groups
Bcell_1432	COG0726	polysaccharide deacetylase
Bcell_1434	COG1827	regulation of RNA biosynthetic process
Bcell_1435	COG1104	cysteine desulfurase activity
Bcell_1436	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Bcell_1437	COG0157	Belongs to the NadC ModD family
Bcell_1439	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Bcell_1440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Bcell_1443	COG3842	ATPase activity
Bcell_1444	COG2508	Transcriptional regulator
Bcell_1447	COG0189	ligase activity
Bcell_1448	COG0189	ligase activity
Bcell_1453	COG1486	melibiose metabolic process
Bcell_1454	COG0561	phosphatase activity
Bcell_1455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bcell_1457	COG0420	3'-5' exonuclease activity
Bcell_1459	COG1510	regulation of RNA biosynthetic process
Bcell_1460	COG0745	RESPONSE REGULATOR receiver
Bcell_1461	COG2205	protein histidine kinase activity
Bcell_1461	COG2770	Histidine kinase
Bcell_1462	COG3481	metal-dependent phosphohydrolase, HD sub domain
Bcell_1464	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Bcell_1468	COG1846	Transcriptional regulator
Bcell_1471	COG0537	adenosine 5'-monophosphoramidase activity
Bcell_1473	COG1131	(ABC) transporter
Bcell_1476	COG1473	amidohydrolase
Bcell_1477	COG0785	Cytochrome C biogenesis protein
Bcell_1478	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcell_1479	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Bcell_1482	COG4191	Histidine kinase
Bcell_1483	COG3290	protein histidine kinase activity
Bcell_1484	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Bcell_1485	COG4492	Belongs to the UPF0735 family
Bcell_1486	COG0077	Prephenate dehydratase
Bcell_1490	COG0632	four-way junction helicase activity
Bcell_1494	COG0343	queuine tRNA-ribosyltransferase activity
Bcell_1495	COG1862	Preprotein translocase
Bcell_1497	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bcell_1498	COG2323	membrane
Bcell_1499	COG2244	polysaccharide biosynthetic process
Bcell_1502	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcell_1502	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcell_1503	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcell_1503	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcell_1504	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bcell_1505	COG5416	Lipopolysaccharide assembly protein A domain
Bcell_1506	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Bcell_1506	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Bcell_1507	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bcell_1508	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bcell_1509	COG1490	D-aminoacyl-tRNA deacylase activity
Bcell_1511	COG0124	histidyl-tRNA synthetase
Bcell_1512	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Bcell_1514	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bcell_1515	COG2364	Membrane
Bcell_1516	COG1959	2 iron, 2 sulfur cluster binding
Bcell_1517	COG1104	cysteine desulfurase activity
Bcell_1518	COG0482	sulfurtransferase activity
Bcell_1520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Bcell_1524	COG0628	permease
Bcell_1525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bcell_1526	COG4472	Bacterial protein of unknown function (DUF965)
Bcell_1528	COG3906	Belongs to the UPF0473 family
Bcell_1529	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bcell_1534	COG0572	uridine kinase
Bcell_1535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Bcell_1537	COG1609	Transcriptional regulator
Bcell_1538	COG1131	(ABC) transporter
Bcell_1544	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bcell_1546	COG0494	nUDIX hydrolase
Bcell_1550	COG1191	sigma factor activity
Bcell_1551	COG0095	Lipoate-protein ligase
Bcell_1555	COG0617	tRNA 3'-terminal CCA addition
Bcell_1557	COG0688	phosphatidylethanolamine metabolic process
Bcell_1567	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bcell_1569	COG1534	Rna-binding protein
Bcell_1571	COG1713	HD superfamily hydrolase involved in NAD metabolism
Bcell_1572	COG0799	negative regulation of ribosome biogenesis
Bcell_1573	COG2226	methyltransferase
Bcell_1574	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bcell_1575	COG1596	polysaccharide export
Bcell_1575	COG1555	photosystem II stabilization
Bcell_1576	COG2131	deaminase
Bcell_1577	COG2333	competence protein COMEC
Bcell_1577	COG0658	competence protein
Bcell_1579	COG1466	dna polymerase III delta subunit
Bcell_1580	COG0268	Binds directly to 16S ribosomal RNA
Bcell_1581	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Bcell_1582	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcell_1584	COG0481	GTPase activity
Bcell_1585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bcell_1586	COG1420	regulation of RNA biosynthetic process
Bcell_1587	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Bcell_1588	COG0443	Heat shock 70 kDa protein
Bcell_1589	COG0484	heat shock protein binding
Bcell_1590	COG2264	protein methyltransferase activity
Bcell_1591	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Bcell_1592	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bcell_1593	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Bcell_1594	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bcell_1595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Bcell_1596	COG1610	YqeY-like protein
Bcell_1597	COG1030	water channel activity
Bcell_1598	COG4864	UPF0365 protein
Bcell_1602	COG1702	phosphate starvation-inducible protein PhoH
Bcell_1603	COG1480	7TM receptor with intracellular HD hydrolase
Bcell_1605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Bcell_1607	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Bcell_1609	COG1381	Involved in DNA repair and RecF pathway recombination
Bcell_1610	COG0752	glycyl-tRNA synthetase alpha subunit
Bcell_1611	COG0751	glycine-tRNA ligase activity
Bcell_1612	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Bcell_1613	COG3344	reverse transcriptase
Bcell_1614	COG1671	Belongs to the UPF0178 family
Bcell_1615	COG0358	DNA primase activity
Bcell_1616	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Bcell_1618	COG0584	glycerophosphoryl diester phosphodiesterase
Bcell_1620	COG2384	SAM-dependent methyltransferase
Bcell_1621	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Bcell_1622	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Bcell_1623	COG1329	Transcriptional regulator
Bcell_1625	COG0513	Belongs to the DEAD box helicase family
Bcell_1626	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Bcell_1628	COG1121	(ABC) transporter
Bcell_1629	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bcell_1630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Bcell_1632	COG1121	(ABC) transporter
Bcell_1633	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bcell_1634	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bcell_1635	COG0735	belongs to the Fur family
Bcell_1636	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
Bcell_1637	COG4709	membrane
Bcell_1638	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Bcell_1640	COG2814	Major facilitator Superfamily
Bcell_1641	COG4086	secreted protein
Bcell_1642	COG1030	water channel activity
Bcell_1643	COG1396	sequence-specific DNA binding
Bcell_1645	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bcell_1649	COG0477	Major facilitator Superfamily
Bcell_1650	COG0768	penicillin binding
Bcell_1654	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bcell_1655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Bcell_1659	COG0457	Tetratricopeptide repeat
Bcell_1659	COG0705	Rhomboid family
Bcell_1661	COG0697	spore germination
Bcell_1665	COG1940	carbohydrate kinase activity
Bcell_1667	COG0011	TIGRFAM Protein of
Bcell_1669	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_1673	COG4980	gas vesicle protein
Bcell_1674	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bcell_1675	COG1459	type II secretion system
Bcell_1677	COG4537	Required for transformation and DNA binding
Bcell_1682	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bcell_1685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bcell_1686	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Bcell_1688	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Bcell_1689	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_1691	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcell_1692	COG1321	iron dependent repressor
Bcell_1693	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bcell_1697	COG0006	proline dipeptidase activity
Bcell_1698	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Bcell_1701	COG3854	ATPases associated with a variety of cellular activities
Bcell_1710	COG0511	ligase activity, forming carbon-carbon bonds
Bcell_1711	COG0439	Biotin carboxylase
Bcell_1712	COG1302	Protein conserved in bacteria
Bcell_1713	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bcell_1715	COG1570	exodeoxyribonuclease VII activity
Bcell_1716	COG1722	exodeoxyribonuclease VII activity
Bcell_1719	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Bcell_1720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Bcell_1721	COG1438	arginine binding
Bcell_1722	COG0497	DNA recombination
Bcell_1723	COG0750	zinc metalloprotease
Bcell_1724	COG0745	RESPONSE REGULATOR receiver
Bcell_1726	COG0463	Glycosyl transferase, family 2
Bcell_1729	COG3290	protein histidine kinase activity
Bcell_1729	COG3829	transcription factor binding
Bcell_1730	COG0280	phosphate acetyltransferase
Bcell_1732	COG3426	butyrate kinase activity
Bcell_1733	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bcell_1734	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bcell_1735	COG0022	dehydrogenase e1 component
Bcell_1736	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcell_1742	COG4129	membrane
Bcell_1743	COG1376	ErfK ybiS ycfS ynhG family protein
Bcell_1744	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcell_1744	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcell_1745	COG0346	lactoylglutathione lyase activity
Bcell_1746	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Bcell_1747	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bcell_1749	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bcell_1751	COG2257	FlhB HrpN YscU SpaS Family
Bcell_1754	COG1728	Protein conserved in bacteria
Bcell_1755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcell_1757	COG1902	pentaerythritol trinitrate reductase activity
Bcell_1758	COG0517	IMP dehydrogenase activity
Bcell_1761	COG2861	carbohydrate metabolic process
Bcell_1762	COG0789	Transcriptional regulator
Bcell_1764	COG1233	COG1233 Phytoene dehydrogenase and related
Bcell_1766	COG0300	oxidoreductase activity
Bcell_1767	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bcell_1770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bcell_1771	COG0367	asparagine synthase
Bcell_1775	COG2190	(PTS) system
Bcell_1777	COG0701	Predicted permease
Bcell_1778	COG1968	undecaprenyl-diphosphatase activity
Bcell_1779	COG0667	Aldo Keto reductase
Bcell_1782	COG0494	nUDIX hydrolase
Bcell_1783	COG1379	DNA repair
Bcell_1784	COG1300	Membrane
Bcell_1785	COG0735	belongs to the Fur family
Bcell_1787	COG4974	Belongs to the 'phage' integrase family
Bcell_1792	COG1686	Belongs to the peptidase S11 family
Bcell_1793	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcell_1799	COG0697	spore germination
Bcell_1800	COG0019	diaminopimelate decarboxylase activity
Bcell_1801	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bcell_1803	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bcell_1803	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bcell_1804	COG0307	riboflavin synthase, alpha
Bcell_1805	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Bcell_1805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Bcell_1806	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Bcell_1807	COG3344	reverse transcriptase
Bcell_1808	COG1547	Domain of unknown function (DUF309)
Bcell_1809	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Bcell_1810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Bcell_1812	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bcell_1813	COG2323	membrane
Bcell_1817	COG1686	Belongs to the peptidase S11 family
Bcell_1818	COG2715	membrane protein required for spore maturation
Bcell_1819	COG0700	Nucleoside recognition
Bcell_1820	COG1187	pseudouridine synthase activity
Bcell_1822	COG1333	cytochrome c biogenesis protein
Bcell_1823	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bcell_1824	COG0745	RESPONSE REGULATOR receiver
Bcell_1825	COG5002	protein histidine kinase activity
Bcell_1826	COG2096	Adenosyltransferase
Bcell_1830	COG1141	Ferredoxin
Bcell_1832	COG0514	ATP-dependent DNA helicase (RecQ)
Bcell_1833	COG1266	CAAX protease self-immunity
Bcell_1841	COG4862	establishment of competence for transformation
Bcell_1842	COG0492	ferredoxin-NADP+ reductase activity
Bcell_1844	COG2339	peptidase activity
Bcell_1846	COG3773	Cell wall hydrolase
Bcell_1846	COG3409	Peptidoglycan-binding domain 1 protein
Bcell_1847	COG2959	enzyme of heme biosynthesis
Bcell_1849	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Bcell_1851	COG0539	negative regulation of cytoplasmic translation
Bcell_1852	COG1304	FMN binding
Bcell_1855	COG1160	GTP binding
Bcell_1856	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Bcell_1857	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Bcell_1861	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bcell_1863	COG0302	gtp cyclohydrolase
Bcell_1865	COG0142	geranyltranstransferase activity
Bcell_1866	COG2226	methyltransferase
Bcell_1869	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Bcell_1870	COG0142	geranyltranstransferase activity
Bcell_1871	COG0105	UTP biosynthetic process
Bcell_1872	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bcell_1873	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Bcell_1874	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Bcell_1875	COG4401	Chorismate mutase type I
Bcell_1877	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bcell_1878	COG0134	indole-3-glycerol-phosphate synthase activity
Bcell_1879	COG0133	tryptophan synthase activity
Bcell_1880	COG0159	tryptophan synthase activity
Bcell_1881	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Bcell_1882	COG0287	Prephenate dehydrogenase
Bcell_1883	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Bcell_1885	COG0457	Tetratricopeptide repeat
Bcell_1887	COG5582	Belongs to the UPF0302 family
Bcell_1889	COG0723	plastoquinol--plastocyanin reductase activity
Bcell_1890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bcell_1892	COG4347	Protein of unknown function (DUF1405)
Bcell_1894	COG2738	Putative neutral zinc metallopeptidase
Bcell_1895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_1896	COG1694	Mazg nucleotide pyrophosphohydrolase
Bcell_1897	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Bcell_1898	COG1803	Methylglyoxal synthase
Bcell_1899	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bcell_1900	COG0438	transferase activity, transferring glycosyl groups
Bcell_1901	COG0617	tRNA 3'-terminal CCA addition
Bcell_1904	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Bcell_1905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Bcell_1907	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Bcell_1907	COG1199	ATP-dependent helicase activity
Bcell_1909	COG0402	S-adenosylhomocysteine deaminase activity
Bcell_1912	COG0017	Asparaginyl-tRNA synthetase
Bcell_1913	COG3935	DnaD domain protein
Bcell_1914	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Bcell_1916	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcell_1916	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bcell_1917	COG3331	DNA recombination
Bcell_1924	COG1335	isochorismatase
Bcell_1927	COG1413	lyase activity
Bcell_1930	COG3402	PFAM membrane-flanked domain
Bcell_1931	COG3428	Bacterial PH domain
Bcell_1935	COG1597	lipid kinase activity
Bcell_1937	COG0805	protein transport
Bcell_1938	COG1428	Deoxynucleoside kinase
Bcell_1939	COG1428	Deoxynucleoside kinase
Bcell_1941	COG4667	esterase of the alpha-beta hydrolase superfamily
Bcell_1942	COG2814	Major facilitator Superfamily
Bcell_1949	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bcell_1951	COG0114	fumarate hydratase activity
Bcell_1954	COG1686	Belongs to the peptidase S11 family
Bcell_1956	COG0436	Aminotransferase
Bcell_1957	COG2135	peptidase activity
Bcell_1958	COG0567	Dehydrogenase, E1 component
Bcell_1959	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcell_1960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bcell_1962	COG0398	Pfam SNARE associated Golgi protein
Bcell_1965	COG1074	ATP-dependent DNA helicase activity
Bcell_1966	COG0420	3'-5' exonuclease activity
Bcell_1967	COG0419	ATPase involved in DNA repair
Bcell_1969	COG0488	(ABC) transporter
Bcell_1970	COG1164	Oligoendopeptidase f
Bcell_1976	COG1012	belongs to the aldehyde dehydrogenase family
Bcell_1976	COG1454	alcohol dehydrogenase
Bcell_1977	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Bcell_1980	COG2223	nitrite transmembrane transporter activity
Bcell_1982	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_1984	COG2340	Cysteine-rich secretory protein family
Bcell_1985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bcell_1989	COG3180	Ammonia monooxygenase
Bcell_1990	COG2267	carboxylic ester hydrolase activity
Bcell_1991	COG0346	lactoylglutathione lyase activity
Bcell_1992	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Bcell_1993	COG1917	Cupin 2, conserved barrel domain protein
Bcell_1994	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Bcell_1995	COG0456	acetyltransferase
Bcell_1997	COG4294	response to UV
Bcell_1998	COG0714	Associated with various cellular activities
Bcell_2002	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
Bcell_2003	COG5002	protein histidine kinase activity
Bcell_2004	COG0745	RESPONSE REGULATOR receiver
Bcell_2007	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Bcell_2008	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bcell_2010	COG2368	4-hydroxyphenylacetate
Bcell_2011	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bcell_2012	COG0004	ammonium transporteR
Bcell_2014	COG2176	DNA-directed DNA polymerase activity
Bcell_2015	COG0789	Transcriptional regulator
Bcell_2016	COG0697	spore germination
Bcell_2018	COG5522	Integral membrane protein (intg_mem_TP0381)
Bcell_2020	COG4844	belongs to the
Bcell_2021	COG2814	Major facilitator Superfamily
Bcell_2023	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_2024	COG1280	lysine exporter protein (LysE YggA)
Bcell_2025	COG1113	amino acid transport
Bcell_2027	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Bcell_2027	COG2080	2 iron, 2 sulfur cluster binding
Bcell_2031	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bcell_2035	COG0778	Nitroreductase
Bcell_2036	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_2038	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Bcell_2044	COG0697	spore germination
Bcell_2047	COG0531	amino acid
Bcell_2050	COG2996	Protein conserved in bacteria
Bcell_2051	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bcell_2055	COG1196	nuclear chromosome segregation
Bcell_2055	COG0741	lytic transglycosylase activity
Bcell_2055	COG0739	heme binding
Bcell_2059	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
Bcell_2060	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_2066	COG0702	epimerase
Bcell_2071	COG2318	DinB family
Bcell_2072	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bcell_2097	COG0740	serine-type endopeptidase activity
Bcell_2113	COG4974	Belongs to the 'phage' integrase family
Bcell_2140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Bcell_2144	COG2323	membrane
Bcell_2148	COG0398	Pfam SNARE associated Golgi protein
Bcell_2149	COG3858	chitin binding
Bcell_2149	COG1388	LysM domain
Bcell_2150	COG1247	-acetyltransferase
Bcell_2151	COG0697	spore germination
Bcell_2153	COG0464	growth
Bcell_2154	COG0824	Thioesterase
Bcell_2157	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Bcell_2158	COG0613	PHP domain protein
Bcell_2160	COG2814	Major facilitator Superfamily
Bcell_2171	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bcell_2173	COG0784	Response regulator, receiver
Bcell_2173	COG0835	chemotaxis
Bcell_2176	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bcell_2177	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bcell_2178	COG1418	mRNA catabolic process
Bcell_2179	COG0791	NLP P60 protein
Bcell_2179	COG1388	LysM domain
Bcell_2180	COG0693	protein deglycase activity
Bcell_2182	COG2814	Major facilitator Superfamily
Bcell_2184	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcell_2191	COG0791	NLP P60 protein
Bcell_2191	COG1388	LysM domain
Bcell_2193	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bcell_2194	COG3852	Histidine kinase
Bcell_2196	COG0205	6-phosphofructokinase activity
Bcell_2197	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bcell_2201	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bcell_2202	COG1111	helicase
Bcell_2202	COG1205	dead DEAH box helicase
Bcell_2203	COG3359	exonuclease
Bcell_2206	COG4474	Belongs to the UPF0398 family
Bcell_2207	COG3599	regulation of cell shape
Bcell_2208	COG0328	RNA-DNA hybrid ribonuclease activity
Bcell_2209	COG0116	Belongs to the methyltransferase superfamily
Bcell_2211	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bcell_2213	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Bcell_2215	COG1832	CoA-binding protein
Bcell_2216	COG0187	DNA topoisomerase II activity
Bcell_2217	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bcell_2218	COG0697	spore germination
Bcell_2226	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Bcell_2227	COG0583	DNA-binding transcription factor activity
Bcell_2228	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bcell_2229	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Bcell_2235	COG5609	conserved protein (DUF2294)
Bcell_2236	COG2223	nitrite transmembrane transporter activity
Bcell_2240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bcell_2241	COG3409	Peptidoglycan-binding domain 1 protein
Bcell_2241	COG3773	Cell wall hydrolase
Bcell_2247	COG1131	(ABC) transporter
Bcell_2249	COG2814	Major facilitator Superfamily
Bcell_2257	COG1131	(ABC) transporter
Bcell_2258	COG4152	abc transporter atp-binding protein
Bcell_2259	COG1668	transmembrane transport
Bcell_2260	COG2197	response regulator
Bcell_2261	COG4585	Histidine kinase
Bcell_2262	COG3239	Fatty acid desaturase
Bcell_2263	COG1082	Xylose isomerase domain protein TIM barrel
Bcell_2264	COG0673	inositol 2-dehydrogenase activity
Bcell_2267	COG2207	Transcriptional regulator
Bcell_2270	COG1307	EDD domain protein, DegV family
Bcell_2272	COG2814	Major facilitator Superfamily
Bcell_2275	COG1346	cytolysis
Bcell_2276	COG1380	Effector of murein hydrolase LrgA
Bcell_2278	COG2814	Major facilitator Superfamily
Bcell_2280	COG5578	integral membrane protein
Bcell_2281	COG0395	ABC-type sugar transport system, permease component
Bcell_2282	COG1175	transmembrane transport
Bcell_2287	COG0114	fumarate hydratase activity
Bcell_2290	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bcell_2291	COG0405	Gamma-glutamyltransferase
Bcell_2292	COG0217	transcriptional regulatory protein
Bcell_2295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bcell_2300	COG2151	metal-sulfur cluster biosynthetic enzyme
Bcell_2301	COG1278	Cold shock
Bcell_2302	COG1695	Transcriptional regulator
Bcell_2309	COG2226	methyltransferase
Bcell_2310	COG0300	oxidoreductase activity
Bcell_2315	COG0109	protoheme IX farnesyltransferase activity
Bcell_2317	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Bcell_2318	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bcell_2323	COG1119	ATPase activity
Bcell_2329	COG3459	Glycosyltransferase 36 associated
Bcell_2330	COG0698	ribose 5-phosphate isomerase
Bcell_2331	COG2200	EAL domain
Bcell_2338	COG0726	polysaccharide deacetylase
Bcell_2341	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Bcell_2343	COG0561	phosphatase activity
Bcell_2344	COG0840	transmembrane signaling receptor activity
Bcell_2345	COG1506	peptidase
Bcell_2345	COG0823	Involved in the tonB-independent uptake of proteins
Bcell_2345	COG4946	Tricorn protease homolog
Bcell_2351	COG2027	D-alanyl-D-alanine carboxypeptidase
Bcell_2355	COG1271	oxidase subunit
Bcell_2356	COG1294	oxidase, subunit
Bcell_2357	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bcell_2359	COG2340	Cysteine-rich secretory protein family
Bcell_2360	COG2197	response regulator
Bcell_2362	COG1388	LysM domain
Bcell_2362	COG4942	peptidase
Bcell_2363	COG2273	Hydrolase Family 16
Bcell_2366	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bcell_2367	COG0010	Belongs to the arginase family
Bcell_2371	COG1595	DNA-templated transcription, initiation
Bcell_2372	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Bcell_2373	COG0720	synthase
Bcell_2374	COG0602	queuosine metabolic process
Bcell_2375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bcell_2376	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bcell_2380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Bcell_2381	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Bcell_2387	COG2217	Heavy metal translocating P-type atpase
Bcell_2388	COG1937	Protein conserved in bacteria
Bcell_2391	COG1132	(ABC) transporter
Bcell_2392	COG1132	(ABC) transporter
Bcell_2393	COG3763	UPF0154 protein
Bcell_2395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Bcell_2397	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bcell_2399	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bcell_2407	COG0174	glutamine synthetase
Bcell_2408	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Bcell_2409	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bcell_2410	COG0464	growth
Bcell_2412	COG1923	regulation of RNA biosynthetic process
Bcell_2413	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Bcell_2414	COG2136	Putative SAM-dependent methyltransferase
Bcell_2414	COG2521	methyltransferase
Bcell_2415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Bcell_2416	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Bcell_2419	COG4550	Control of competence regulator ComK, YlbF/YmcA
Bcell_2420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bcell_2422	COG0156	8-amino-7-oxononanoate synthase activity
Bcell_2423	COG1063	alcohol dehydrogenase
Bcell_2424	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bcell_2425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bcell_2425	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bcell_2426	COG2359	stage V sporulation protein S
Bcell_2427	COG1692	metallophosphoesterase
Bcell_2428	COG1418	mRNA catabolic process
Bcell_2429	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Bcell_2430	COG0513	Belongs to the DEAD box helicase family
Bcell_2431	COG1546	Belongs to the CinA family
Bcell_2431	COG1058	Belongs to the CinA family
Bcell_2432	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bcell_2433	COG1426	Protein conserved in bacteria
Bcell_2436	COG0300	oxidoreductase activity
Bcell_2437	COG0612	Peptidase, M16
Bcell_2438	COG0612	Peptidase, M16
Bcell_2439	COG1674	ftsk spoiiie
Bcell_2441	COG0740	serine-type endopeptidase activity
Bcell_2443	COG0527	aspartate kinase activity
Bcell_2444	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bcell_2445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bcell_2446	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bcell_2447	COG1873	PFAM PRC-barrel domain
Bcell_2448	COG0612	Peptidase, M16
Bcell_2449	COG0726	polysaccharide deacetylase
Bcell_2450	COG1185	polyribonucleotide nucleotidyltransferase activity
Bcell_2451	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Bcell_2452	COG0196	riboflavin kinase activity
Bcell_2454	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Bcell_2455	COG1550	Protein conserved in bacteria
Bcell_2456	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Bcell_2457	COG1358	cellular component organization or biogenesis
Bcell_2458	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Bcell_2459	COG0195	Participates in both transcription termination and antitermination
Bcell_2460	COG0779	Required for maturation of 30S ribosomal subunits
Bcell_2461	COG2176	DNA-directed DNA polymerase activity
Bcell_2462	COG0442	prolyl-tRNA aminoacylation
Bcell_2463	COG0750	zinc metalloprotease
Bcell_2464	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Bcell_2465	COG4589	Belongs to the CDS family
Bcell_2466	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Bcell_2467	COG0233	cytoplasmic translational termination
Bcell_2468	COG0528	UMP kinase activity
Bcell_2469	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Bcell_2470	COG0052	Belongs to the universal ribosomal protein uS2 family
Bcell_2474	COG1191	sigma factor activity
Bcell_2476	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Bcell_2477	COG1776	CheC inhibitor of MCP methylation
Bcell_2478	COG0835	chemotaxis
Bcell_2479	COG0643	Histidine kinase
Bcell_2479	COG2198	Histidine kinase
Bcell_2480	COG2201	protein-glutamate methylesterase activity
Bcell_2481	COG0455	bacterial-type flagellum organization
Bcell_2482	COG1419	protein localization to endoplasmic reticulum
Bcell_2483	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bcell_2484	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bcell_2485	COG1684	flagellar biosynthetic protein fliR
Bcell_2486	COG1987	bacterial-type flagellum assembly
Bcell_2487	COG1338	Plays a role in the flagellum-specific transport system
Bcell_2488	COG3190	flagellar
Bcell_2489	COG2201	protein-glutamate methylesterase activity
Bcell_2490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcell_2490	COG1776	CheC inhibitor of MCP methylation
Bcell_2491	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcell_2493	COG1582	Flagellar protein (FlbD)
Bcell_2496	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Bcell_2499	COG2882	bacterial-type flagellum organization
Bcell_2500	COG1157	protein secretion by the type III secretion system
Bcell_2502	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcell_2503	COG1766	The M ring may be actively involved in energy transduction
Bcell_2504	COG1677	Flagellar hook-basal body complex protein FliE
Bcell_2505	COG1558	bacterial-type flagellum-dependent cell motility
Bcell_2506	COG1815	bacterial-type flagellum-dependent cell motility
Bcell_2507	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Bcell_2508	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Bcell_2509	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Bcell_2510	COG4974	Belongs to the 'phage' integrase family
Bcell_2511	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Bcell_2512	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bcell_2513	COG0758	DNA mediated transformation
Bcell_2514	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bcell_2515	COG0045	succinate-CoA ligase (ADP-forming) activity
Bcell_2517	COG2257	FlhB HrpN YscU SpaS Family
Bcell_2519	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Bcell_2522	COG0335	large ribosomal subunit rRNA binding
Bcell_2523	COG0336	Belongs to the RNA methyltransferase TrmD family
Bcell_2526	COG1837	Belongs to the UPF0109 family
Bcell_2527	COG0228	four-way junction DNA binding
Bcell_2528	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Bcell_2529	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Bcell_2530	COG0552	protein localization to endoplasmic reticulum
Bcell_2531	COG1196	nuclear chromosome segregation
Bcell_2532	COG4840	Belongs to the UPF0435 family
Bcell_2533	COG0571	ribonuclease III activity
Bcell_2534	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bcell_2535	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_2536	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Bcell_2537	COG0416	fatty acid biosynthetic process
Bcell_2538	COG1349	DNA-binding transcription factor activity
Bcell_2539	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Bcell_2540	COG1760	l-serine dehydratase
Bcell_2541	COG1760	l-serine dehydratase
Bcell_2542	COG1307	EDD domain protein, DegV family
Bcell_2543	COG1461	Dihydroxyacetone kinase
Bcell_2544	COG1302	Protein conserved in bacteria
Bcell_2545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Bcell_2547	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bcell_2548	COG1162	GTPase activity
Bcell_2549	COG2815	serine threonine protein kinase
Bcell_2549	COG0515	serine threonine protein kinase
Bcell_2550	COG0631	protein serine/threonine phosphatase activity
Bcell_2551	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Bcell_2552	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bcell_2552	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bcell_2553	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Bcell_2554	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Bcell_2555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bcell_2556	COG1758	RNA polymerase activity
Bcell_2557	COG0194	GDP metabolic process
Bcell_2558	COG2052	Domain of unknown function (DUF370)
Bcell_2559	COG1561	YicC-like family, N-terminal region
Bcell_2561	COG1132	(ABC) transporter
Bcell_2562	COG1132	(ABC) transporter
Bcell_2563	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Bcell_2564	COG0284	orotidine-5'-phosphate decarboxylase activity
Bcell_2565	COG0167	dihydroorotate dehydrogenase activity
Bcell_2566	COG0543	2 iron, 2 sulfur cluster binding
Bcell_2567	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Bcell_2570	COG0540	Belongs to the ATCase OTCase family
Bcell_2571	COG2233	PERMEase
Bcell_2572	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Bcell_2573	COG0564	pseudouridine synthase activity
Bcell_2574	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Bcell_2575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Bcell_2576	COG3599	regulation of cell shape
Bcell_2577	COG2302	S4 RNA-binding domain
Bcell_2578	COG0762	integral membrane protein
Bcell_2579	COG1799	cell septum assembly
Bcell_2580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Bcell_2581	COG1873	PFAM PRC-barrel domain
Bcell_2582	COG1191	sigma factor activity
Bcell_2583	COG1191	sigma factor activity
Bcell_2585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Bcell_2586	COG0849	cell division
Bcell_2587	COG3856	small basic protein
Bcell_2588	COG3879	Bacterial protein of unknown function (DUF881)
Bcell_2589	COG3879	Bacterial protein of unknown function (DUF881)
Bcell_2590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Bcell_2591	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Bcell_2592	COG0772	Belongs to the SEDS family
Bcell_2594	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bcell_2596	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Bcell_2597	COG0768	penicillin binding
Bcell_2600	COG0275	rRNA processing
Bcell_2601	COG2001	Belongs to the MraZ family
Bcell_2602	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Bcell_2604	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bcell_2605	COG0454	-acetyltransferase
Bcell_2608	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Bcell_2609	COG1399	metal-binding, possibly nucleic acid-binding protein
Bcell_2610	COG1323	Belongs to the UPF0348 family
Bcell_2611	COG3480	Lon protease (S16) C-terminal proteolytic domain
Bcell_2612	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bcell_2613	COG3314	Sporulation integral membrane protein YlbJ
Bcell_2614	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Bcell_2615	COG0742	ribosomal rna small subunit methyltransferase
Bcell_2616	COG2814	Major facilitator Superfamily
Bcell_2617	COG4471	UPF0298 protein
Bcell_2618	COG3679	Belongs to the UPF0342 family
Bcell_2620	COG0513	Belongs to the DEAD box helicase family
Bcell_2623	COG2340	Cysteine-rich secretory protein family
Bcell_2624	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Bcell_2631	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Bcell_2634	COG1131	(ABC) transporter
Bcell_2639	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bcell_2641	COG0109	protoheme IX farnesyltransferase activity
Bcell_2642	COG1612	heme a metabolic process
Bcell_2643	COG0783	Belongs to the Dps family
Bcell_2644	COG4838	Belongs to the UPF0358 family
Bcell_2647	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bcell_2648	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Bcell_2651	COG4896	Protein conserved in bacteria
Bcell_2654	COG0483	inositol monophosphate 1-phosphatase activity
Bcell_2656	COG4493	Belongs to the UPF0637 family
Bcell_2658	COG1982	Orn Lys Arg decarboxylase major
Bcell_2663	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bcell_2664	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcell_2666	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcell_2667	COG0022	dehydrogenase e1 component
Bcell_2672	COG0561	phosphatase activity
Bcell_2674	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bcell_2676	COG0569	domain protein
Bcell_2677	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcell_2678	COG0450	alkyl hydroperoxide reductase
Bcell_2679	COG0668	transmembrane transport
Bcell_2681	COG1473	amidohydrolase
Bcell_2682	COG2171	N-acyltransferase activity
Bcell_2684	COG1393	Belongs to the ArsC family
Bcell_2685	COG0668	transmembrane transport
Bcell_2689	COG0778	Nitroreductase
Bcell_2690	COG1854	S-ribosylhomocysteine lyase activity
Bcell_2692	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bcell_2694	COG1695	Transcriptional regulator
Bcell_2695	COG0596	Alpha beta hydrolase
Bcell_2697	COG1051	belongs to the nudix hydrolase family
Bcell_2700	COG2153	protein acetylation
Bcell_2702	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bcell_2731	COG0740	serine-type endopeptidase activity
Bcell_2734	COG1802	Transcriptional regulator
Bcell_2734	COG4626	Terminase
Bcell_2744	COG1484	DNA-dependent DNA replication
Bcell_2745	COG3935	DnaD domain protein
Bcell_2752	COG1396	sequence-specific DNA binding
Bcell_2753	COG0582	viral genome integration into host DNA
Bcell_2755	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Bcell_2756	COG4844	belongs to the
Bcell_2757	COG1136	(ABC) transporter
Bcell_2758	COG0577	efflux transmembrane transporter activity
Bcell_2759	COG0577	efflux transmembrane transporter activity
Bcell_2765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bcell_2768	COG3583	domain protein
Bcell_2768	COG3584	3D domain protein
Bcell_2770	COG0601	transmembrane transport
Bcell_2771	COG0189	ligase activity
Bcell_2774	COG2323	membrane
Bcell_2775	COG0673	inositol 2-dehydrogenase activity
Bcell_2776	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bcell_2777	COG1129	ABC transporter
Bcell_2778	COG1879	ABC-type sugar transport system periplasmic component
Bcell_2781	COG2116	formate transmembrane transporter activity
Bcell_2782	COG4589	Belongs to the CDS family
Bcell_2787	COG3344	reverse transcriptase
Bcell_2790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bcell_2792	COG1695	Transcriptional regulator
Bcell_2794	COG0328	RNA-DNA hybrid ribonuclease activity
Bcell_2800	COG1486	melibiose metabolic process
Bcell_2801	COG2971	BadF BadG BcrA BcrD
Bcell_2805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bcell_2808	COG1595	DNA-templated transcription, initiation
Bcell_2810	COG4149	molybdate abc transporter
Bcell_2812	COG3559	Exporter of polyketide antibiotics
Bcell_2813	COG1131	(ABC) transporter
Bcell_2815	COG1254	Belongs to the acylphosphatase family
Bcell_2820	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bcell_2821	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bcell_2827	COG0438	transferase activity, transferring glycosyl groups
Bcell_2831	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bcell_2833	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Bcell_2834	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bcell_2835	COG0826	peptidase U32
Bcell_2841	COG1070	Carbohydrate kinase
Bcell_2843	COG0473	3-isopropylmalate dehydrogenase activity
Bcell_2844	COG2226	methyltransferase
Bcell_2845	COG1247	-acetyltransferase
Bcell_2849	COG2364	Membrane
Bcell_2853	COG0710	3-dehydroquinate dehydratase activity
Bcell_2854	COG2720	vancomycin resistance protein
Bcell_2857	COG1122	ATPase activity
Bcell_2858	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bcell_2863	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Bcell_2863	COG2508	Transcriptional regulator
Bcell_2864	COG0686	Belongs to the AlaDH PNT family
Bcell_2869	COG0640	Transcriptional regulator
Bcell_2873	COG1305	Transglutaminase-like
Bcell_2875	COG0714	Associated with various cellular activities
Bcell_2876	COG1363	Peptidase, m42
Bcell_2878	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bcell_2886	COG1088	dTDP-glucose 4,6-dehydratase activity
Bcell_2888	COG3344	reverse transcriptase
Bcell_2889	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Bcell_2890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Bcell_2891	COG0564	pseudouridine synthase activity
Bcell_2892	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Bcell_2893	COG2357	RelA SpoT domain protein
Bcell_2895	COG4116	CYTH
Bcell_2896	COG0741	lytic transglycosylase activity
Bcell_2897	COG2346	COG2346, Truncated hemoglobins
Bcell_2900	COG1164	Oligoendopeptidase f
Bcell_2904	COG0861	Integral membrane protein TerC family
Bcell_2905	COG1393	Belongs to the ArsC family
Bcell_2907	COG0456	acetyltransferase
Bcell_2909	COG1418	mRNA catabolic process
Bcell_2912	COG0180	Tryptophanyl-tRNA synthetase
Bcell_2915	COG5504	Zn-dependent protease
Bcell_2916	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bcell_2917	COG2197	response regulator
Bcell_2918	COG4585	Histidine kinase
Bcell_2919	COG4758	membrane
Bcell_2920	COG1316	TRANSCRIPTIONal
Bcell_2921	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bcell_2922	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bcell_2925	COG1744	ABC transporter substrate-binding protein PnrA-like
Bcell_2926	COG2267	carboxylic ester hydrolase activity
Bcell_2929	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bcell_2930	COG2223	nitrite transmembrane transporter activity
Bcell_2933	COG0437	4 iron, 4 sulfur cluster binding
Bcell_2934	COG0243	molybdopterin cofactor binding
Bcell_2936	COG4841	protein insertion into membrane
Bcell_2937	COG0535	radical SAM domain protein
Bcell_2940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Bcell_2941	COG0314	molybdopterin synthase activity
Bcell_2942	COG1763	Mo-molybdopterin cofactor biosynthetic process
Bcell_2943	COG0303	'Molybdopterin
Bcell_2944	COG1999	signal sequence binding
Bcell_2945	COG3336	cytochrome c oxidase
Bcell_2946	COG0561	phosphatase activity
Bcell_2950	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Bcell_2955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bcell_2957	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_2961	COG0840	transmembrane signaling receptor activity
Bcell_2963	COG1874	Beta-galactosidase
Bcell_2964	COG3833	ABC-type maltose transport systems, permease component
Bcell_2965	COG1175	transmembrane transport
Bcell_2966	COG2182	Extracellular solute-binding protein
Bcell_2968	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcell_2969	COG0628	permease
Bcell_2970	COG1917	Cupin 2, conserved barrel domain protein
Bcell_2970	COG2207	Transcriptional regulator
Bcell_2971	COG0534	Mate efflux family protein
Bcell_2974	COG1737	Transcriptional regulator
Bcell_2975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bcell_2976	COG1509	lysine 2,3-aminomutase activity
Bcell_2979	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bcell_2984	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Bcell_2988	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bcell_2994	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bcell_2996	COG2205	protein histidine kinase activity
Bcell_2998	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Bcell_2999	COG3300	MHYT domain
Bcell_2999	COG5001	Diguanylate cyclase
Bcell_3005	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Bcell_3006	COG3639	organic phosphonate transmembrane transporter activity
Bcell_3007	COG3639	organic phosphonate transmembrane transporter activity
Bcell_3019	COG0745	RESPONSE REGULATOR receiver
Bcell_3020	COG0704	Plays a role in the regulation of phosphate uptake
Bcell_3021	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Bcell_3022	COG0581	inorganic phosphate transmembrane transporter activity
Bcell_3023	COG0573	inorganic phosphate transmembrane transporter activity
Bcell_3026	COG2868	ribosomal protein
Bcell_3027	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Bcell_3028	COG1530	ribonuclease E activity
Bcell_3029	COG1994	Peptidase M50
Bcell_3030	COG0739	heme binding
Bcell_3032	COG2894	cell division
Bcell_3033	COG0850	regulation of cytokinetic process
Bcell_3035	COG1792	Involved in formation and maintenance of cell shape
Bcell_3036	COG1077	Cell shape determining protein MreB Mrl
Bcell_3043	COG0210	DNA helicase
Bcell_3044	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Bcell_3047	COG0367	asparagine synthase
Bcell_3050	COG3682	Transcriptional regulator
Bcell_3051	COG2217	Heavy metal translocating P-type atpase
Bcell_3054	COG2205	protein histidine kinase activity
Bcell_3055	COG0745	RESPONSE REGULATOR receiver
Bcell_3058	COG3850	Histidine kinase
Bcell_3058	COG5002	protein histidine kinase activity
Bcell_3059	COG0745	RESPONSE REGULATOR receiver
Bcell_3065	COG0398	Pfam SNARE associated Golgi protein
Bcell_3066	COG2132	Multicopper oxidase
Bcell_3067	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Bcell_3072	COG0739	heme binding
Bcell_3074	COG0791	NLP P60 protein
Bcell_3074	COG1388	LysM domain
Bcell_3091	COG2003	Belongs to the UPF0758 family
Bcell_3093	COG1027	Aspartate ammonia-lyase
Bcell_3099	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Bcell_3100	COG2165	general secretion pathway protein
Bcell_3103	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bcell_3107	COG3706	GGDEF domain
Bcell_3108	COG0285	dihydrofolate synthase activity
Bcell_3109	COG0189	ligase activity
Bcell_3115	COG3011	Protein conserved in bacteria
Bcell_3118	COG0525	valine-tRNA ligase activity
Bcell_3122	COG1388	LysM domain
Bcell_3122	COG1388	LysM domain
Bcell_3123	COG0385	Bile acid
Bcell_3125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bcell_3126	COG0113	porphobilinogen synthase activity
Bcell_3128	COG0181	hydroxymethylbilane synthase activity
Bcell_3129	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bcell_3130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Bcell_3132	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Bcell_3134	COG1067	ATP-dependent peptidase activity
Bcell_3134	COG0470	DNA polymerase III
Bcell_3136	COG1809	phosphosulfolactate synthase activity
Bcell_3137	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Bcell_3138	COG0544	peptidyl-prolyl cis-trans isomerase activity
Bcell_3139	COG1477	protein flavinylation
Bcell_3139	COG0457	Tetratricopeptide repeat
Bcell_3142	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcell_3143	COG1595	DNA-templated transcription, initiation
Bcell_3145	COG0622	Phosphoesterase
Bcell_3146	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Bcell_3147	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Bcell_3148	COG5401	PFAM Sporulation and spore germination
Bcell_3150	COG1846	Transcriptional regulator
Bcell_3151	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Bcell_3152	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcell_3153	COG2197	response regulator
Bcell_3155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bcell_3156	COG1053	succinate dehydrogenase
Bcell_3157	COG2009	succinate dehydrogenase
Bcell_3158	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bcell_3159	COG1719	4-vinyl reductase, 4VR
Bcell_3161	COG0322	excinuclease ABC activity
Bcell_3162	COG3118	belongs to the thioredoxin family
Bcell_3163	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bcell_3164	COG2086	electron transfer activity
Bcell_3165	COG1024	Enoyl-CoA hydratase
Bcell_3166	COG1309	transcriptional regulator
Bcell_3167	COG0318	PFAM AMP-dependent synthetase and ligase
Bcell_3169	COG0395	ABC-type sugar transport system, permease component
Bcell_3170	COG1175	transmembrane transport
Bcell_3171	COG4753	response regulator
Bcell_3171	COG2207	Transcriptional regulator
Bcell_3172	COG2972	Histidine kinase
Bcell_3174	COG1349	DNA-binding transcription factor activity
Bcell_3175	COG3395	kinase activity
Bcell_3176	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Bcell_3177	COG3766	membrane
Bcell_3178	COG1193	negative regulation of DNA recombination
Bcell_3179	COG1796	DNA polymerase
Bcell_3179	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bcell_3184	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcell_3184	COG0072	phenylalanine-tRNA ligase activity
Bcell_3185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Bcell_3186	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bcell_3188	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bcell_3189	COG1363	Peptidase, m42
Bcell_3192	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Bcell_3193	COG1793	dna ligase
Bcell_3194	COG1793	dna ligase
Bcell_3194	COG3285	dna ligase
Bcell_3197	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Bcell_3199	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Bcell_3200	COG3300	MHYT domain
Bcell_3200	COG5001	Diguanylate cyclase
Bcell_3201	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bcell_3204	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bcell_3205	COG1484	DNA-dependent DNA replication
Bcell_3206	COG3611	Membrane attachment protein
Bcell_3207	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Bcell_3209	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Bcell_3211	COG0237	dephospho-CoA kinase activity
Bcell_3212	COG1971	Probably functions as a manganese efflux pump
Bcell_3213	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Bcell_3214	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcell_3214	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcell_3215	COG5002	protein histidine kinase activity
Bcell_3216	COG0745	RESPONSE REGULATOR receiver
Bcell_3218	COG0039	L-malate dehydrogenase activity
Bcell_3219	COG0538	isocitrate dehydrogenase activity
Bcell_3220	COG0372	Belongs to the citrate synthase family
Bcell_3221	COG2707	UPF0756 membrane protein
Bcell_3222	COG0628	permease
Bcell_3223	COG3030	protein affecting phage T7 exclusion by the F plasmid
Bcell_3225	COG0205	6-phosphofructokinase activity
Bcell_3226	COG0825	malonyl-CoA metabolic process
Bcell_3227	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Bcell_3229	COG0281	malic enzyme
Bcell_3230	COG0587	DNA-directed DNA polymerase activity
Bcell_3233	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Bcell_3235	COG4109	DRTGG domain
Bcell_3237	COG0006	proline dipeptidase activity
Bcell_3239	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_3246	COG0827	DNA restriction-modification system
Bcell_3247	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Bcell_3249	COG3874	Sporulation protein YtfJ
Bcell_3251	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Bcell_3252	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Bcell_3254	COG0301	tRNA thio-modification
Bcell_3255	COG1104	cysteine desulfurase activity
Bcell_3256	COG1114	Component of the transport system for branched-chain amino acids
Bcell_3258	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Bcell_3259	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bcell_3260	COG1309	transcriptional regulator
Bcell_3261	COG1956	GAF domain-containing protein
Bcell_3262	COG2203	Gaf domain
Bcell_3262	COG2199	diguanylate cyclase activity
Bcell_3263	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Bcell_3267	COG0454	-acetyltransferase
Bcell_3268	COG0517	IMP dehydrogenase activity
Bcell_3269	COG0123	including yeast histone deacetylase and acetoin utilization protein
Bcell_3270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bcell_3274	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bcell_3274	COG1605	Chorismate mutase
Bcell_3277	COG4980	gas vesicle protein
Bcell_3280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Bcell_3284	COG1674	ftsk spoiiie
Bcell_3285	COG4848	Belongs to the UPF0354 family
Bcell_3286	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcell_3290	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Bcell_3291	COG1363	Peptidase, m42
Bcell_3293	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_3294	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Bcell_3297	COG0510	thiamine kinase activity
Bcell_3300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bcell_3301	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bcell_3302	COG1349	DNA-binding transcription factor activity
Bcell_3303	COG1187	pseudouridine synthase activity
Bcell_3305	COG0772	Belongs to the SEDS family
Bcell_3306	COG0772	Belongs to the SEDS family
Bcell_3307	COG1733	regulation of RNA biosynthetic process
Bcell_3308	COG2244	polysaccharide biosynthetic process
Bcell_3310	COG0432	Pfam Uncharacterised protein family UPF0047
Bcell_3311	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bcell_3313	COG2081	HI0933 family
Bcell_3314	COG0495	leucyl-tRNA aminoacylation
Bcell_3315	COG2814	Major facilitator Superfamily
Bcell_3317	COG1242	4 iron, 4 sulfur cluster binding
Bcell_3318	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Bcell_3321	COG2267	carboxylic ester hydrolase activity
Bcell_3322	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Bcell_3323	COG0671	phosphoesterase, PA-phosphatase related
Bcell_3324	COG0438	transferase activity, transferring glycosyl groups
Bcell_3325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Bcell_3326	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcell_3327	COG1116	anion transmembrane transporter activity
Bcell_3328	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcell_3329	COG0494	nUDIX hydrolase
Bcell_3330	COG0746	molybdenum cofactor guanylyltransferase activity
Bcell_3337	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bcell_3338	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bcell_3340	COG1063	alcohol dehydrogenase
Bcell_3342	COG0475	glutathione-regulated potassium exporter activity
Bcell_3342	COG0589	response to stress
Bcell_3343	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcell_3344	COG1410	methionine synthase
Bcell_3344	COG0646	methionine synthase
Bcell_3345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Bcell_3345	COG0646	methionine synthase
Bcell_3346	COG0626	cystathionine gamma-synthase activity
Bcell_3347	COG0626	cystathionine gamma-synthase activity
Bcell_3351	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bcell_3352	COG0529	Catalyzes the synthesis of activated sulfate
Bcell_3353	COG2046	Belongs to the sulfate adenylyltransferase family
Bcell_3354	COG0175	sulfate reduction
Bcell_3355	COG0306	phosphate transporter
Bcell_3356	COG1012	belongs to the aldehyde dehydrogenase family
Bcell_3357	COG0460	homoserine dehydrogenase
Bcell_3358	COG1473	amidohydrolase
Bcell_3360	COG0006	proline dipeptidase activity
Bcell_3361	COG2508	Transcriptional regulator
Bcell_3366	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bcell_3367	COG1609	Transcriptional regulator
Bcell_3369	COG1234	tRNA 3'-trailer cleavage
Bcell_3370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Bcell_3371	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Bcell_3374	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bcell_3376	COG0166	Belongs to the GPI family
Bcell_3377	COG1979	alcohol dehydrogenase
Bcell_3378	COG2155	Conserved Protein
Bcell_3379	COG1098	S1 RNA binding domain
Bcell_3380	COG0733	neurotransmitter:sodium symporter activity
Bcell_3381	COG0436	Aminotransferase
Bcell_3382	COG1522	sequence-specific DNA binding
Bcell_3384	COG0644	oxidoreductase
Bcell_3385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bcell_3387	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bcell_3388	COG1131	(ABC) transporter
Bcell_3394	COG2056	Na+-H+ antiporter family
Bcell_3395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Bcell_3396	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Bcell_3398	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Bcell_3399	COG3584	3D domain protein
Bcell_3402	COG1252	NADH dehydrogenase
Bcell_3403	COG0492	ferredoxin-NADP+ reductase activity
Bcell_3404	COG0316	Belongs to the HesB IscA family
Bcell_3405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bcell_3406	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Bcell_3408	COG4844	belongs to the
Bcell_3409	COG1252	NADH dehydrogenase
Bcell_3410	COG4837	Protein of unknown function (DUF1462)
Bcell_3411	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Bcell_3412	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bcell_3413	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bcell_3414	COG0647	UMP catabolic process
Bcell_3416	COG2445	Protein of unknown function DUF86
Bcell_3419	COG4470	Protein conserved in bacteria
Bcell_3421	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Bcell_3422	COG0739	heme binding
Bcell_3423	COG0733	neurotransmitter:sodium symporter activity
Bcell_3425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Bcell_3426	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Bcell_3428	COG3377	Domain of unknown function (DUF1805)
Bcell_3429	COG0737	Belongs to the 5'-nucleotidase family
Bcell_3430	COG0730	response to heat
Bcell_3431	COG1801	Protein of unknown function DUF72
Bcell_3432	COG0719	Fe-S assembly protein
Bcell_3433	COG0822	iron-sulfur transferase activity
Bcell_3434	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bcell_3435	COG0719	Fe-S assembly protein
Bcell_3436	COG0396	ATPase activity
Bcell_3438	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Bcell_3439	COG1464	Belongs to the NlpA lipoprotein family
Bcell_3440	COG2011	ABC-type metal ion transport system permease component
Bcell_3441	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Bcell_3443	COG0477	Major facilitator Superfamily
Bcell_3445	COG0509	glycine decarboxylation via glycine cleavage system
Bcell_3446	COG1393	Belongs to the ArsC family
Bcell_3448	COG1960	acyl-CoA dehydrogenase activity
Bcell_3449	COG0183	Belongs to the thiolase family
Bcell_3450	COG1024	Enoyl-CoA hydratase
Bcell_3450	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcell_3452	COG5577	PFAM Coat F domain
Bcell_3454	COG1404	Belongs to the peptidase S8 family
Bcell_3455	COG0201	protein transport
Bcell_3456	COG0460	homoserine dehydrogenase
Bcell_3463	COG3386	PFAM SMP-30 Gluconolaconase
Bcell_3464	COG1368	sulfuric ester hydrolase activity
Bcell_3466	COG1178	ABC-type Fe3 transport system permease component
Bcell_3474	COG1595	DNA-templated transcription, initiation
Bcell_3476	COG3883	PFAM NLP P60 protein
Bcell_3476	COG0791	NLP P60 protein
Bcell_3477	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bcell_3480	COG0739	heme binding
Bcell_3483	COG5002	protein histidine kinase activity
Bcell_3484	COG0745	RESPONSE REGULATOR receiver
Bcell_3485	COG3764	Sortase (surface protein transpeptidase)
Bcell_3486	COG2217	Heavy metal translocating P-type atpase
Bcell_3490	COG0569	domain protein
Bcell_3491	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bcell_3492	COG0523	cobalamin synthesis protein
Bcell_3495	COG2239	Acts as a magnesium transporter
Bcell_3496	COG1285	pathogenesis
Bcell_3497	COG2239	Acts as a magnesium transporter
Bcell_3498	COG2239	Acts as a magnesium transporter
Bcell_3499	COG0671	phosphoesterase, PA-phosphatase related
Bcell_3502	COG5002	protein histidine kinase activity
Bcell_3503	COG0745	RESPONSE REGULATOR receiver
Bcell_3507	COG0395	ABC-type sugar transport system, permease component
Bcell_3508	COG1175	transmembrane transport
Bcell_3511	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Bcell_3512	COG0557	exoribonuclease II activity
Bcell_3513	COG1647	Serine aminopeptidase, S33
Bcell_3515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bcell_3516	COG0148	phosphopyruvate hydratase activity
Bcell_3517	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Bcell_3518	COG0149	triose-phosphate isomerase activity
Bcell_3519	COG0126	phosphoglycerate kinase activity
Bcell_3520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bcell_3523	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Bcell_3525	COG0740	serine-type endopeptidase activity
Bcell_3526	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcell_3527	COG1481	regulation of sporulation
Bcell_3528	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Bcell_3529	COG1660	Displays ATPase and GTPase activities
Bcell_3530	COG1051	belongs to the nudix hydrolase family
Bcell_3531	COG0492	ferredoxin-NADP+ reductase activity
Bcell_3532	COG0457	Tetratricopeptide repeat
Bcell_3533	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Bcell_3533	COG0140	phosphoribosyl-ATP diphosphatase activity
Bcell_3534	COG0107	imidazoleglycerol-phosphate synthase activity
Bcell_3535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Bcell_3536	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Bcell_3537	COG0131	Imidazoleglycerol-phosphate dehydratase
Bcell_3538	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Bcell_3539	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Bcell_3540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Bcell_3570	COG0110	maltose O-acetyltransferase activity
Bcell_3571	COG0546	phosphoglycolate phosphatase activity
Bcell_3572	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bcell_3573	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Bcell_3574	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Bcell_3575	COG1950	PFAM Membrane protein of
Bcell_3577	COG3595	metallopeptidase activity
Bcell_3578	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bcell_3579	COG0556	nucleotide-excision repair
Bcell_3580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcell_3581	COG3409	Peptidoglycan-binding domain 1 protein
Bcell_3581	COG0793	Belongs to the peptidase S41A family
Bcell_3582	COG0739	heme binding
Bcell_3583	COG2177	Part of the ABC transporter FtsEX involved in
Bcell_3584	COG2884	Cell division ATP-binding protein ftsE
Bcell_3586	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcell_3588	COG0653	protein targeting
Bcell_3589	COG3711	transcriptional antiterminator
Bcell_3590	COG2190	(PTS) system
Bcell_3590	COG1263	PTS System
Bcell_3590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcell_3591	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Bcell_3592	COG1278	Cold shock
Bcell_3593	COG0367	asparagine synthase
Bcell_3594	COG0629	single-stranded DNA binding
Bcell_3596	COG1482	cell wall glycoprotein biosynthetic process
Bcell_3600	COG1516	flagellar protein fliS
Bcell_3601	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Bcell_3603	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bcell_3604	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bcell_3605	COG2089	acid synthase
Bcell_3607	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Bcell_3608	COG0151	Belongs to the GarS family
Bcell_3617	COG1086	Polysaccharide biosynthesis protein
Bcell_3619	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bcell_3620	COG2197	response regulator
Bcell_3621	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Bcell_3622	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Bcell_3624	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bcell_3625	COG1256	bacterial-type flagellum assembly
Bcell_3625	COG4786	Flagellar basal body rod
Bcell_3627	COG2747	anti-sigma28 factor FlgM
Bcell_3629	COG1040	competence protein
Bcell_3630	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bcell_3631	COG1307	EDD domain protein, DegV family
Bcell_3634	COG1739	Uncharacterized protein family UPF0029
Bcell_3636	COG1316	TRANSCRIPTIONal
Bcell_3638	COG1316	TRANSCRIPTIONal
Bcell_3639	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Bcell_3640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bcell_3641	COG4193	domain, Protein
Bcell_3642	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Bcell_3643	COG1216	Glycosyl transferase, family 2
Bcell_3646	COG0463	Glycosyl transferase, family 2
Bcell_3649	COG1215	transferase activity, transferring glycosyl groups
Bcell_3654	COG3764	Sortase (surface protein transpeptidase)
Bcell_3655	COG0768	penicillin binding
Bcell_3661	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bcell_3662	COG3300	MHYT domain
Bcell_3662	COG5001	Diguanylate cyclase
Bcell_3663	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Bcell_3665	COG5002	protein histidine kinase activity
Bcell_3666	COG1744	ABC transporter substrate-binding protein PnrA-like
Bcell_3667	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Bcell_3668	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Bcell_3669	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Bcell_3670	COG1376	ErfK ybiS ycfS ynhG family protein
Bcell_3672	COG0840	transmembrane signaling receptor activity
Bcell_3675	COG1278	Cold shock
Bcell_3679	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Bcell_3682	COG2839	Protein conserved in bacteria
Bcell_3688	COG1091	dTDP-4-dehydrorhamnose reductase activity
Bcell_3690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bcell_3694	COG1473	amidohydrolase
Bcell_3696	COG0363	glucosamine-6-phosphate deaminase activity
Bcell_3697	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bcell_3699	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcell_3701	COG3964	amidohydrolase
Bcell_3702	COG2706	6-phosphogluconolactonase activity
Bcell_3704	COG0395	ABC-type sugar transport system, permease component
Bcell_3705	COG1175	transmembrane transport
Bcell_3708	COG1472	Belongs to the glycosyl hydrolase 3 family
Bcell_3710	COG0484	heat shock protein binding
Bcell_3712	COG0443	Heat shock 70 kDa protein
Bcell_3714	COG0464	growth
Bcell_3715	COG0484	heat shock protein binding
Bcell_3723	COG2855	membrane
Bcell_3724	COG5583	Uncharacterized small protein (DUF2292)
Bcell_3727	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcell_3731	COG3291	Pkd domain containing protein
Bcell_3731	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Bcell_3733	COG0346	lactoylglutathione lyase activity
Bcell_3735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bcell_3735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bcell_3738	COG3290	protein histidine kinase activity
Bcell_3743	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bcell_3744	COG1129	ABC transporter
Bcell_3745	COG1879	ABC-type sugar transport system periplasmic component
Bcell_3747	COG0436	Aminotransferase
Bcell_3748	COG2186	Transcriptional regulator
Bcell_3749	COG1312	Catalyzes the dehydration of D-mannonate
Bcell_3751	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcell_3756	COG0667	Aldo Keto reductase
Bcell_3757	COG0346	lactoylglutathione lyase activity
Bcell_3758	COG0194	GDP metabolic process
Bcell_3759	COG1472	Belongs to the glycosyl hydrolase 3 family
Bcell_3766	COG3273	potassium ion transport
Bcell_3766	COG0471	metal ion transport
Bcell_3770	COG0788	formyltetrahydrofolate deformylase activity
Bcell_3787	COG0366	Alpha amylase catalytic
Bcell_3788	COG0366	Alpha amylase catalytic
Bcell_3790	COG3833	ABC-type maltose transport systems, permease component
Bcell_3791	COG1175	transmembrane transport
Bcell_3792	COG2182	Extracellular solute-binding protein
Bcell_3793	COG1609	Transcriptional regulator
Bcell_3796	COG0395	ABC-type sugar transport system, permease component
Bcell_3801	COG1733	regulation of RNA biosynthetic process
Bcell_3804	COG1131	(ABC) transporter
Bcell_3808	COG0174	glutamine synthetase
Bcell_3810	COG1842	Phage shock protein A
Bcell_3813	COG2340	Cysteine-rich secretory protein family
Bcell_3818	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcell_3818	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcell_3820	COG0737	Belongs to the 5'-nucleotidase family
Bcell_3820	COG1525	nuclease
Bcell_3820	COG4085	toxin activity
Bcell_3821	COG0840	transmembrane signaling receptor activity
Bcell_3824	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Bcell_3825	COG2197	response regulator
Bcell_3827	COG3290	protein histidine kinase activity
Bcell_3827	COG0840	transmembrane signaling receptor activity
Bcell_3828	COG5002	protein histidine kinase activity
Bcell_3828	COG3447	MASE1 domain protein
Bcell_3828	COG5001	Diguanylate cyclase
Bcell_3833	COG2801	Transposase and inactivated derivatives
Bcell_3837	COG1309	transcriptional regulator
Bcell_3841	COG1476	TRANSCRIPTIONal
Bcell_3850	COG3655	Transcriptional regulator
Bcell_3852	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_3855	COG4682	membrane
Bcell_3862	COG0653	protein targeting
Bcell_3867	COG1388	LysM domain
Bcell_3867	COG3942	CHAP domain
Bcell_3870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bcell_3874	COG2801	Transposase and inactivated derivatives
Bcell_3878	COG2124	cytochrome p450
Bcell_3879	COG0840	transmembrane signaling receptor activity
Bcell_3887	COG0544	peptidyl-prolyl cis-trans isomerase activity
Bcell_3904	COG4372	Transposase
Bcell_3905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Bcell_3919	COG2746	aminoglycoside 3-N-acetyltransferase activity
Bcell_3920	COG1476	TRANSCRIPTIONal
Bcell_3925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcell_3927	COG1476	TRANSCRIPTIONal
Bcell_3946	COG0135	phosphoribosylanthranilate isomerase activity
Bcell_3955	COG1051	belongs to the nudix hydrolase family
Bcell_3961	COG0840	transmembrane signaling receptor activity
Bcell_3965	COG0346	lactoylglutathione lyase activity
Bcell_3993	COG0463	Glycosyl transferase, family 2
Bcell_3996	COG3279	Response regulator of the LytR AlgR family
Bcell_3997	COG0745	RESPONSE REGULATOR receiver
Bcell_3997	COG2972	Histidine kinase
Bcell_3998	COG2801	Transposase and inactivated derivatives
Bcell_4003	COG0640	Transcriptional regulator
Bcell_4005	COG5646	InterPro IPR014922
Bcell_4008	COG0110	maltose O-acetyltransferase activity
Bcell_4013	COG2801	Transposase and inactivated derivatives
Bcell_4029	COG0456	acetyltransferase
Bcell_4030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Bcell_4032	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bcell_4035	COG0726	polysaccharide deacetylase
Bcell_4036	COG1388	LysM domain
Bcell_4036	COG0791	NLP P60 protein
Bcell_4043	COG4786	Flagellar basal body rod
Bcell_4044	COG4786	Flagellar basal body rod
Bcell_4045	COG1077	Cell shape determining protein MreB Mrl
Bcell_4046	COG1609	Transcriptional regulator
Bcell_4047	COG0739	heme binding
Bcell_4051	COG2385	sporulation resulting in formation of a cellular spore
Bcell_4052	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bcell_4055	COG1007	ATP synthesis coupled electron transport
Bcell_4057	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bcell_4058	COG0713	ATP synthesis coupled electron transport
Bcell_4059	COG0839	Belongs to the complex I subunit 6 family
Bcell_4061	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Bcell_4062	COG0649	NAD binding
Bcell_4063	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bcell_4064	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bcell_4067	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Bcell_4068	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Bcell_4070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Bcell_4071	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Bcell_4074	COG0356	it plays a direct role in the translocation of protons across the membrane
Bcell_4077	COG1404	Belongs to the peptidase S8 family
Bcell_4078	COG0656	L-ascorbic acid biosynthetic process
Bcell_4080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Bcell_4082	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Bcell_4085	COG0698	ribose 5-phosphate isomerase
Bcell_4086	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bcell_4087	COG1971	Probably functions as a manganese efflux pump
Bcell_4088	COG0009	L-threonylcarbamoyladenylate synthase
Bcell_4092	COG3328	transposase activity
Bcell_4093	COG2890	protein-(glutamine-N5) methyltransferase activity
Bcell_4094	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Bcell_4095	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bcell_4099	COG1435	thymidine kinase activity
Bcell_4100	COG0254	rRNA binding
Bcell_4101	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Bcell_4102	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bcell_4103	COG0191	fructose-bisphosphate aldolase activity
Bcell_4104	COG2204	response regulator
Bcell_4106	COG1595	DNA-templated transcription, initiation
Bcell_4110	COG0504	CTP synthase activity
Bcell_4111	COG3343	RNA polymerase activity
Bcell_4112	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcell_4112	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcell_4112	COG1703	isobutyryl-CoA mutase activity
Bcell_4114	COG1960	acyl-CoA dehydrogenase activity
Bcell_4115	COG1960	acyl-CoA dehydrogenase activity
Bcell_4116	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcell_4117	COG0183	Belongs to the thiolase family
Bcell_4118	COG2181	nitrate reductase activity
Bcell_4118	COG0247	lactate metabolic process
Bcell_4119	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bcell_4120	COG2217	Heavy metal translocating P-type atpase
Bcell_4123	COG0018	arginyl-trna synthetase
Bcell_4124	COG4506	Protein conserved in bacteria
Bcell_4126	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcell_4129	COG3465	dGTPase activity
Bcell_4130	COG1078	dGTPase activity
Bcell_4131	COG4844	belongs to the
Bcell_4132	COG0095	Lipoate-protein ligase
Bcell_4133	COG0280	phosphate acetyltransferase
Bcell_4136	COG3773	Cell wall hydrolase
Bcell_4138	COG2363	Small membrane protein
Bcell_4140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bcell_4141	COG0765	amino acid transport
Bcell_4142	COG1126	abc transporter atp-binding protein
Bcell_4145	COG0702	epimerase
Bcell_4146	COG2084	Dehydrogenase
Bcell_4147	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Bcell_4148	COG2201	protein-glutamate methylesterase activity
Bcell_4150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bcell_4153	COG2309	aminopeptidase activity
Bcell_4156	COG1115	amino acid carrier protein
Bcell_4159	COG1657	PFAM Prenyltransferase squalene oxidase
Bcell_4163	COG0251	oxidation-reduction process
Bcell_4164	COG1984	allophanate hydrolase subunit 2
Bcell_4165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Bcell_4166	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Bcell_4167	COG1072	(Pantothenic acid kinase))
Bcell_4169	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bcell_4169	COG0723	plastoquinol--plastocyanin reductase activity
Bcell_4171	COG0460	homoserine dehydrogenase
Bcell_4172	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Bcell_4173	COG0083	homoserine kinase activity
Bcell_4174	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bcell_4175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Bcell_4181	COG0706	membrane insertase activity
Bcell_4186	COG2235	arginine
Bcell_4187	COG0667	Aldo Keto reductase
Bcell_4189	COG1328	CTP reductase activity
Bcell_4190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcell_4191	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcell_4192	COG0561	phosphatase activity
Bcell_4194	COG3852	Histidine kinase
Bcell_4197	COG0165	Argininosuccinate lyase
Bcell_4198	COG0137	argininosuccinate synthase activity
Bcell_4199	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Bcell_4200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Bcell_4201	COG0505	Belongs to the CarA family
Bcell_4202	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bcell_4203	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Bcell_4204	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Bcell_4205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Bcell_4206	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bcell_4208	COG3858	chitin binding
Bcell_4210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bcell_4212	COG0697	spore germination
Bcell_4219	COG0601	transmembrane transport
Bcell_4220	COG0747	negative chemotaxis
Bcell_4225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bcell_4226	COG1116	anion transmembrane transporter activity
Bcell_4227	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcell_4228	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcell_4229	COG1028	Short-chain dehydrogenase reductase Sdr
Bcell_4230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Bcell_4233	COG2843	Capsule synthesis protein
Bcell_4234	COG0584	glycerophosphoryl diester phosphodiesterase
Bcell_4239	COG1714	RDD family
Bcell_4242	COG0714	Associated with various cellular activities
Bcell_4249	COG0450	alkyl hydroperoxide reductase
Bcell_4253	COG0579	oxidoreductase
Bcell_4254	COG2200	EAL domain
Bcell_4255	COG2205	protein histidine kinase activity
Bcell_4256	COG2391	methyltransferase activity
Bcell_4261	COG1136	(ABC) transporter
Bcell_4264	COG1472	Belongs to the glycosyl hydrolase 3 family
Bcell_4288	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Bcell_4290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Bcell_4292	COG4974	Belongs to the 'phage' integrase family
Bcell_4299	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Bcell_4301	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcell_4302	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Bcell_4303	COG4853	Protein conserved in bacteria
Bcell_4304	COG4863	YycH protein
Bcell_4305	COG5002	protein histidine kinase activity
Bcell_4306	COG0745	RESPONSE REGULATOR receiver
Bcell_4307	COG0739	heme binding
Bcell_4307	COG1196	nuclear chromosome segregation
Bcell_4307	COG0741	lytic transglycosylase activity
Bcell_4308	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Bcell_4309	COG0305	Participates in initiation and elongation during chromosome replication
Bcell_4310	COG0359	binds to the 23S rRNA
Bcell_4311	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Bcell_4313	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Bcell_4314	COG0629	single-stranded DNA binding
Bcell_4315	COG0360	Binds together with S18 to 16S ribosomal RNA
Bcell_4316	COG0012	GTP binding
Bcell_4317	COG4481	Protein conserved in bacteria
Bcell_4318	COG3949	Membrane
Bcell_4320	COG1811	Na channel or pump
Bcell_4321	COG1475	DNA binding
Bcell_4322	COG1192	Involved in chromosome partitioning
Bcell_4323	COG1475	DNA binding
Bcell_4324	COG0357	Ribosomal RNA small subunit methyltransferase G
Bcell_4325	COG0445	tRNA wobble uridine modification
Bcell_4326	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Bcell_4327	COG1847	R3H domain protein
Bcell_4328	COG0706	membrane insertase activity
Bcell_4331	COG0230	Belongs to the bacterial ribosomal protein bL34 family