locus-tag	class	description
AS54_1005	COG0477	Major facilitator Superfamily
AS54_1006	COG3290	protein histidine kinase activity
AS54_1007	COG4565	transcriptional regulatory protein
AS54_1008	COG3181	Tripartite tricarboxylate transporter family receptor
AS54_1010	COG0582	viral genome integration into host DNA
AS54_1015	COG1401	restriction endodeoxyribonuclease activity
AS54_1018	COG1401	restriction endodeoxyribonuclease activity
AS54_1022	COG0305	Participates in initiation and elongation during chromosome replication
AS54_1027	COG0477	Major facilitator Superfamily
AS54_1037	COG3320	Male sterility
AS54_1037	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS54_1041	COG1183	phosphatidylcholine synthase activity
AS54_1047	COG2376	Dihydroxyacetone kinase
AS54_1049	COG2376	Dihydroxyacetone kinase
AS54_105	COG1982	Orn Lys Arg decarboxylase major
AS54_1050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS54_1051	COG1959	2 iron, 2 sulfur cluster binding
AS54_1054	COG0457	Tetratricopeptide repeat
AS54_1056	COG3437	response regulator, receiver
AS54_1056	COG2770	Histidine kinase
AS54_1066	COG3237	CsbD-like
AS54_107	COG0470	DNA polymerase III
AS54_1071	COG1191	sigma factor activity
AS54_1073	COG2208	phosphoserine phosphatase activity
AS54_1074	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS54_1075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS54_1075	COG2198	Histidine kinase
AS54_1075	COG2205	protein histidine kinase activity
AS54_1075	COG0784	Response regulator, receiver
AS54_108	COG1774	PSP1 C-terminal conserved region
AS54_1080	COG0393	Putative heavy-metal-binding
AS54_1088	COG0420	3'-5' exonuclease activity
AS54_1089	COG4717	serine-type aminopeptidase activity
AS54_1095	COG0346	lactoylglutathione lyase activity
AS54_1096	COG0346	lactoylglutathione lyase activity
AS54_1097	COG0457	Tetratricopeptide repeat
AS54_1099	COG2267	carboxylic ester hydrolase activity
AS54_11	COG0463	Glycosyl transferase, family 2
AS54_110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS54_1103	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS54_1104	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS54_1106	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS54_1116	COG0477	Major facilitator Superfamily
AS54_1117	COG0477	Major facilitator Superfamily
AS54_1119	COG3973	AAA domain
AS54_112	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS54_1120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS54_1124	COG4980	gas vesicle protein
AS54_1125	COG0537	adenosine 5'-monophosphoramidase activity
AS54_1126	COG1131	(ABC) transporter
AS54_1127	COG4473	ABC transporter
AS54_113	COG2002	toxin-antitoxin pair type II binding
AS54_114	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS54_114	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS54_1141	COG1309	transcriptional regulator
AS54_1143	COG3402	PFAM membrane-flanked domain
AS54_1144	COG3428	Bacterial PH domain
AS54_1149	COG0778	Nitroreductase
AS54_115	COG0084	hydrolase, TatD family'
AS54_1155	COG3402	PFAM membrane-flanked domain
AS54_1156	COG3428	Bacterial PH domain
AS54_1157	COG2329	Antibiotic biosynthesis monooxygenase
AS54_1158	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS54_116	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS54_1169	COG1309	transcriptional regulator
AS54_1170	COG1511	domain protein
AS54_1176	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AS54_1178	COG2378	regulation of single-species biofilm formation
AS54_1179	COG1609	Transcriptional regulator
AS54_1181	COG1234	tRNA 3'-trailer cleavage
AS54_1182	COG0095	Lipoate-protein ligase
AS54_1184	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_119	COG4466	Protein conserved in bacteria
AS54_1195	COG1073	alpha beta
AS54_1196	COG1408	metallophosphoesterase
AS54_1198	COG1078	dGTPase activity
AS54_12	COG1309	transcriptional regulator
AS54_1200	COG1595	DNA-templated transcription, initiation
AS54_1201	COG3708	Transcriptional regulator
AS54_1201	COG2207	Transcriptional regulator
AS54_1202	COG2205	protein histidine kinase activity
AS54_1203	COG0745	RESPONSE REGULATOR receiver
AS54_1207	COG0501	Belongs to the peptidase M48B family
AS54_1208	COG0697	spore germination
AS54_1211	COG0497	DNA recombination
AS54_1212	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS54_1213	COG2224	Isocitrate lyase
AS54_1215	COG1278	Cold shock
AS54_122	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS54_1220	COG0398	Pfam SNARE associated Golgi protein
AS54_123	COG0251	oxidation-reduction process
AS54_1232	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS54_1237	COG0367	asparagine synthase
AS54_1239	COG0753	catalase activity
AS54_1240	COG0004	ammonium transporteR
AS54_1244	COG2996	Protein conserved in bacteria
AS54_1246	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS54_1248	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_1251	COG0561	phosphatase activity
AS54_1253	COG0542	response to heat
AS54_1255	COG2267	carboxylic ester hydrolase activity
AS54_1258	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_1259	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS54_126	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS54_1260	COG5504	Zn-dependent protease
AS54_1262	COG0180	Tryptophanyl-tRNA synthetase
AS54_1264	COG4166	transmembrane transport
AS54_1265	COG0601	transmembrane transport
AS54_1266	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS54_1267	COG0444	Belongs to the ABC transporter superfamily
AS54_1268	COG4608	Belongs to the ABC transporter superfamily
AS54_1269	COG0534	Mate efflux family protein
AS54_127	COG0193	aminoacyl-tRNA hydrolase activity
AS54_1270	COG4166	transmembrane transport
AS54_1272	COG1393	Belongs to the ArsC family
AS54_1273	COG0861	Integral membrane protein TerC family
AS54_1274	COG4862	establishment of competence for transformation
AS54_1275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS54_1277	COG1164	Oligoendopeptidase f
AS54_1280	COG2346	COG2346, Truncated hemoglobins
AS54_1281	COG4116	CYTH
AS54_1283	COG2357	RelA SpoT domain protein
AS54_1284	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS54_1285	COG0564	pseudouridine synthase activity
AS54_1288	COG0772	Belongs to the SEDS family
AS54_1289	COG1216	Glycosyl transferase, family 2
AS54_129	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS54_1293	COG0463	Glycosyl transferase, family 2
AS54_1293	COG0457	Tetratricopeptide repeat
AS54_1297	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS54_13	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS54_130	COG2002	toxin-antitoxin pair type II binding
AS54_1300	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS54_1308	COG2153	protein acetylation
AS54_131	COG2244	polysaccharide biosynthetic process
AS54_1310	COG2382	esterase
AS54_1313	COG5492	domain, Protein
AS54_1314	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS54_1316	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS54_1316	COG0512	Glutamine amidotransferase of anthranilate synthase
AS54_132	COG3956	TIGRFAM MazG family protein
AS54_1323	COG1620	l-lactate permease
AS54_1324	COG5634	Uncharacterized conserved protein (DUF2278)
AS54_133	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS54_1333	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS54_1335	COG1476	TRANSCRIPTIONal
AS54_1359	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS54_1362	COG4152	abc transporter atp-binding protein
AS54_1363	COG1668	transmembrane transport
AS54_1366	COG2226	methyltransferase
AS54_1368	COG1686	Belongs to the peptidase S11 family
AS54_1369	COG0681	Belongs to the peptidase S26 family
AS54_137	COG1098	S1 RNA binding domain
AS54_1375	COG1012	belongs to the aldehyde dehydrogenase family
AS54_1377	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS54_1378	COG1177	transmembrane transport
AS54_1379	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS54_1381	COG2409	Drug exporters of the RND superfamily
AS54_1383	COG0564	pseudouridine synthase activity
AS54_1385	COG2340	Cysteine-rich secretory protein family
AS54_1386	COG0247	lactate metabolic process
AS54_1387	COG0277	FAD linked oxidase domain protein
AS54_1388	COG3835	regulator
AS54_1390	COG0745	RESPONSE REGULATOR receiver
AS54_1391	COG5002	protein histidine kinase activity
AS54_1392	COG2186	Transcriptional regulator
AS54_1396	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS54_1398	COG2116	formate transmembrane transporter activity
AS54_1399	COG0861	Integral membrane protein TerC family
AS54_14	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS54_14	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS54_140	COG2208	phosphoserine phosphatase activity
AS54_1400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS54_1402	COG2030	dehydratase
AS54_1406	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_1407	COG3243	poly(R)-hydroxyalkanoic acid synthase
AS54_1409	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS54_1412	COG1840	ABC-type Fe3 transport system, periplasmic component
AS54_1413	COG3842	ATPase activity
AS54_1418	COG1349	DNA-binding transcription factor activity
AS54_1421	COG0235	Class ii aldolase
AS54_1423	COG2861	carbohydrate metabolic process
AS54_1425	COG3852	Histidine kinase
AS54_1426	COG1846	Transcriptional regulator
AS54_1428	COG2318	DinB family
AS54_143	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS54_1430	COG5002	protein histidine kinase activity
AS54_1432	COG0720	synthase
AS54_1435	COG4873	Protein conserved in bacteria
AS54_1441	COG1780	Probably involved in ribonucleotide reductase function
AS54_1442	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS54_1443	COG1403	HNH endonuclease
AS54_1444	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS54_1444	COG1372	Participates in initiation and elongation during chromosome replication
AS54_1445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS54_1446	COG1725	Transcriptional regulator
AS54_1447	COG1131	(ABC) transporter
AS54_1449	COG1131	(ABC) transporter
AS54_1450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS54_1453	COG1522	sequence-specific DNA binding
AS54_1455	COG1335	isochorismatase
AS54_1457	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS54_1458	COG2070	2-Nitropropane dioxygenase
AS54_1459	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS54_146	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS54_1461	COG1696	Membrane protein involved in D-alanine export
AS54_1466	COG0716	FMN binding
AS54_147	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS54_1477	COG1846	Transcriptional regulator
AS54_1479	COG1301	dicarboxylic acid transport
AS54_148	COG0512	Glutamine amidotransferase of anthranilate synthase
AS54_1480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS54_1481	COG4709	membrane
AS54_1482	COG3874	Sporulation protein YtfJ
AS54_1487	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS54_1488	COG0028	Belongs to the TPP enzyme family
AS54_1489	COG0440	acetolactate synthase activity
AS54_149	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS54_15	COG0628	permease
AS54_150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS54_1504	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS54_1507	COG1183	phosphatidylcholine synthase activity
AS54_1508	COG1368	sulfuric ester hydrolase activity
AS54_151	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS54_1510	COG0019	diaminopimelate decarboxylase activity
AS54_1514	COG0529	Catalyzes the synthesis of activated sulfate
AS54_1515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS54_1519	COG1648	precorrin-2 dehydrogenase activity
AS54_152	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS54_1520	COG0733	neurotransmitter:sodium symporter activity
AS54_1526	COG1757	Na H antiporter
AS54_1529	COG4758	membrane
AS54_153	COG1396	sequence-specific DNA binding
AS54_1530	COG4585	Histidine kinase
AS54_1531	COG2197	response regulator
AS54_1533	COG1114	Component of the transport system for branched-chain amino acids
AS54_1535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS54_154	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS54_1543	COG0730	response to heat
AS54_1544	COG0306	phosphate transporter
AS54_1545	COG1392	Phosphate transport regulator
AS54_1546	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS54_1549	COG3852	Histidine kinase
AS54_1550	COG1801	Protein of unknown function DUF72
AS54_1552	COG0582	viral genome integration into host DNA
AS54_1553	COG5002	protein histidine kinase activity
AS54_1557	COG0392	lysyltransferase activity
AS54_1557	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS54_1560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS54_1561	COG1686	Belongs to the peptidase S11 family
AS54_1562	COG2715	membrane protein required for spore maturation
AS54_1563	COG0700	Nucleoside recognition
AS54_1564	COG1187	pseudouridine synthase activity
AS54_1566	COG1333	cytochrome c biogenesis protein
AS54_1567	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS54_1568	COG0745	RESPONSE REGULATOR receiver
AS54_1569	COG5002	protein histidine kinase activity
AS54_1570	COG2096	Adenosyltransferase
AS54_1571	COG4942	peptidase
AS54_1573	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AS54_1574	COG1141	Ferredoxin
AS54_1576	COG0514	ATP-dependent DNA helicase (RecQ)
AS54_1577	COG1266	CAAX protease self-immunity
AS54_1579	COG1408	metallophosphoesterase
AS54_1581	COG4862	establishment of competence for transformation
AS54_1582	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS54_1586	COG0492	ferredoxin-NADP+ reductase activity
AS54_1587	COG0252	asparaginase activity
AS54_1601	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS54_1604	COG0142	geranyltranstransferase activity
AS54_1606	COG0142	geranyltranstransferase activity
AS54_1607	COG0105	UTP biosynthetic process
AS54_1610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS54_1611	COG0457	Tetratricopeptide repeat
AS54_1615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS54_1617	COG4347	Protein of unknown function (DUF1405)
AS54_1620	COG2738	Putative neutral zinc metallopeptidase
AS54_1622	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_1623	COG1694	Mazg nucleotide pyrophosphohydrolase
AS54_1626	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS54_1627	COG0438	transferase activity, transferring glycosyl groups
AS54_1634	COG1199	ATP-dependent helicase activity
AS54_1634	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS54_1638	COG3935	DnaD domain protein
AS54_1639	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS54_1641	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS54_1641	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS54_1652	COG0116	Belongs to the methyltransferase superfamily
AS54_1654	COG1199	ATP-dependent helicase activity
AS54_1655	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AS54_1657	COG3173	Aminoglycoside phosphotransferase
AS54_1658	COG0024	Methionine aminopeptidase
AS54_1660	COG2233	PERMEase
AS54_1661	COG2311	Membrane
AS54_1663	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS54_1665	COG0456	acetyltransferase
AS54_1671	COG0754	glutathionylspermidine amidase activity
AS54_1674	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS54_1677	COG0454	-acetyltransferase
AS54_1681	COG0328	RNA-DNA hybrid ribonuclease activity
AS54_1688	COG3403	YqcI/YcgG family
AS54_1689	COG1280	lysine exporter protein (LysE YggA)
AS54_1692	COG3162	membrane
AS54_1693	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS54_1694	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS54_1696	COG0475	glutathione-regulated potassium exporter activity
AS54_1697	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS54_1698	COG0789	Transcriptional regulator
AS54_1698	COG4978	Transcriptional regulator
AS54_1700	COG2323	membrane
AS54_1701	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AS54_1712	COG1923	regulation of RNA biosynthetic process
AS54_1714	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS54_1715	COG1360	Flagellar Motor Protein
AS54_1716	COG2201	protein-glutamate methylesterase activity
AS54_1717	COG2198	Histidine kinase
AS54_1717	COG0643	Histidine kinase
AS54_1718	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS54_1718	COG1776	CheC inhibitor of MCP methylation
AS54_1721	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS54_1725	COG1256	bacterial-type flagellum assembly
AS54_1726	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS54_1727	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AS54_1730	COG1815	bacterial-type flagellum-dependent cell motility
AS54_1731	COG1558	bacterial-type flagellum-dependent cell motility
AS54_1732	COG1677	Flagellar hook-basal body complex protein FliE
AS54_1733	COG1766	The M ring may be actively involved in energy transduction
AS54_1734	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS54_1736	COG1157	protein secretion by the type III secretion system
AS54_174	COG3880	PFAM UvrB UvrC protein
AS54_1743	COG0784	Response regulator, receiver
AS54_1743	COG0835	chemotaxis
AS54_1745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS54_1746	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS54_1747	COG0741	lytic transglycosylase activity
AS54_1749	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS54_1750	COG1776	CheC inhibitor of MCP methylation
AS54_1750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS54_1752	COG1338	Plays a role in the flagellum-specific transport system
AS54_1753	COG1987	bacterial-type flagellum assembly
AS54_1755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS54_1756	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS54_1757	COG1419	protein localization to endoplasmic reticulum
AS54_1758	COG4786	Flagellar basal body rod
AS54_1759	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS54_176	COG0542	response to heat
AS54_1768	COG2329	Antibiotic biosynthesis monooxygenase
AS54_177	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS54_1774	COG3842	ATPase activity
AS54_1775	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS54_1776	COG1177	transmembrane transport
AS54_1777	COG1234	tRNA 3'-trailer cleavage
AS54_1782	COG1686	Belongs to the peptidase S11 family
AS54_1784	COG0406	alpha-ribazole phosphatase activity
AS54_1788	COG1846	Transcriptional regulator
AS54_179	COG4956	integral membrane protein (PIN domain superfamily)
AS54_1790	COG0367	asparagine synthase
AS54_1796	COG1802	Transcriptional regulator
AS54_1797	COG0697	spore germination
AS54_1798	COG0523	cobalamin synthesis protein
AS54_1799	COG0701	Predicted permease
AS54_18	COG3279	Response regulator of the LytR AlgR family
AS54_1802	COG1757	Na H antiporter
AS54_1803	COG0114	fumarate hydratase activity
AS54_1806	COG0534	Mate efflux family protein
AS54_1807	COG3340	Belongs to the peptidase S51 family
AS54_1811	COG0785	Cytochrome C biogenesis protein
AS54_1817	COG2733	membrane
AS54_1824	COG1131	(ABC) transporter
AS54_1827	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS54_1828	COG0528	UMP kinase activity
AS54_183	COG1045	serine acetyltransferase
AS54_1830	COG1027	Aspartate ammonia-lyase
AS54_1831	COG0281	malic enzyme
AS54_1832	COG4191	Histidine kinase
AS54_1833	COG0784	Response regulator, receiver
AS54_1834	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS54_1844	COG1051	belongs to the nudix hydrolase family
AS54_1850	COG1966	Carbon starvation protein
AS54_1852	COG1695	Transcriptional regulator
AS54_1854	COG0477	Major facilitator Superfamily
AS54_1855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_1856	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS54_1857	COG4166	transmembrane transport
AS54_1858	COG2223	nitrite transmembrane transporter activity
AS54_1859	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS54_186	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS54_1862	COG2244	polysaccharide biosynthetic process
AS54_1863	COG0733	neurotransmitter:sodium symporter activity
AS54_1865	COG5566	PFAM Mor transcription activator
AS54_1866	COG2323	membrane
AS54_1869	COG2084	Dehydrogenase
AS54_187	COG3688	RNA-binding protein containing a PIN domain
AS54_1873	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS54_1875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS54_1876	COG0028	Belongs to the TPP enzyme family
AS54_1878	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS54_1880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS54_1885	COG2814	Major facilitator Superfamily
AS54_1886	COG3384	dioxygenase
AS54_189	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS54_1890	COG3279	Response regulator of the LytR AlgR family
AS54_1891	COG0427	acetyl-CoA hydrolase
AS54_1898	COG0582	viral genome integration into host DNA
AS54_19	COG3275	phosphorelay sensor kinase activity
AS54_190	COG0250	Participates in transcription elongation, termination and antitermination
AS54_1900	COG3620	sequence-specific DNA binding
AS54_1911	COG1846	Transcriptional regulator
AS54_1912	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS54_1931	COG0582	viral genome integration into host DNA
AS54_195	COG2813	Specifically methylates the guanine in position
AS54_1961	COG4166	transmembrane transport
AS54_1966	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_1967	COG0745	RESPONSE REGULATOR receiver
AS54_1971	COG1914	H( )-stimulated, divalent metal cation uptake system
AS54_1974	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS54_1976	COG0531	amino acid
AS54_198	COG1358	cellular component organization or biogenesis
AS54_1981	COG2390	Transcriptional regulator
AS54_1983	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_1984	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AS54_1989	COG0006	proline dipeptidase activity
AS54_1990	COG2132	Multicopper oxidase
AS54_1997	COG1114	Component of the transport system for branched-chain amino acids
AS54_1999	COG2372	response to copper ion
AS54_1999	COG1276	copper resistance
AS54_2	COG0840	transmembrane signaling receptor activity
AS54_20	COG2814	Major facilitator Superfamily
AS54_2000	COG4549	nuclear export factor GLE1
AS54_2002	COG0697	spore germination
AS54_2003	COG0583	DNA-binding transcription factor activity
AS54_2004	COG1959	2 iron, 2 sulfur cluster binding
AS54_2005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS54_2006	COG0778	Nitroreductase
AS54_2009	COG0628	permease
AS54_2010	COG0039	L-malate dehydrogenase activity
AS54_2011	COG1231	oxidoreductase activity
AS54_2012	COG0523	cobalamin synthesis protein
AS54_2015	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_2016	COG2030	dehydratase
AS54_2017	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_2019	COG0411	ABC transporter
AS54_2021	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS54_2023	COG0583	DNA-binding transcription factor activity
AS54_2029	COG1271	oxidase subunit
AS54_2030	COG1294	oxidase, subunit
AS54_2031	COG4988	ABC transporter
AS54_2032	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS54_2035	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS54_2036	COG1686	Belongs to the peptidase S11 family
AS54_2038	COG1388	LysM domain
AS54_2038	COG0791	NLP P60 protein
AS54_2040	COG1132	(ABC) transporter
AS54_2041	COG0745	RESPONSE REGULATOR receiver
AS54_2042	COG5002	protein histidine kinase activity
AS54_2043	COG0300	oxidoreductase activity
AS54_2046	COG0726	polysaccharide deacetylase
AS54_2050	COG0460	homoserine dehydrogenase
AS54_2055	COG1316	TRANSCRIPTIONal
AS54_2057	COG0745	RESPONSE REGULATOR receiver
AS54_2058	COG5002	protein histidine kinase activity
AS54_2059	COG0726	polysaccharide deacetylase
AS54_2061	COG1285	pathogenesis
AS54_2062	COG1247	-acetyltransferase
AS54_2064	COG4264	IucA IucC family
AS54_2065	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_2068	COG1082	Xylose isomerase domain protein TIM barrel
AS54_2070	COG2814	Major facilitator Superfamily
AS54_2071	COG1279	arginine transmembrane transporter activity
AS54_2072	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_2074	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS54_2094	COG4695	Portal protein
AS54_21	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS54_2100	COG0577	efflux transmembrane transporter activity
AS54_2101	COG2002	toxin-antitoxin pair type II binding
AS54_2102	COG1404	Belongs to the peptidase S8 family
AS54_2103	COG0640	Transcriptional regulator
AS54_2104	COG0667	Aldo Keto reductase
AS54_2105	COG2814	Major facilitator Superfamily
AS54_2110	COG0840	transmembrane signaling receptor activity
AS54_2113	COG3949	Membrane
AS54_2114	COG0783	Belongs to the Dps family
AS54_2117	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS54_2119	COG1231	oxidoreductase activity
AS54_2120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_2121	COG4989	oxidoreductase activity
AS54_2122	COG0523	cobalamin synthesis protein
AS54_2123	COG0456	acetyltransferase
AS54_2127	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS54_2127	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS54_2129	COG0702	epimerase
AS54_2131	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS54_2133	COG4166	transmembrane transport
AS54_2136	COG0406	alpha-ribazole phosphatase activity
AS54_2138	COG5337	Spore coat protein CotH
AS54_2139	COG1051	belongs to the nudix hydrolase family
AS54_2140	COG0586	Pfam SNARE associated Golgi protein
AS54_2141	COG2244	polysaccharide biosynthetic process
AS54_2143	COG0701	Predicted permease
AS54_2144	COG3689	TIGRFAM TIGR03943 family protein
AS54_2145	COG1607	acyl-coa hydrolase
AS54_2146	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS54_2149	COG0702	epimerase
AS54_2150	COG2839	Protein conserved in bacteria
AS54_2151	COG1253	flavin adenine dinucleotide binding
AS54_2154	COG1114	Component of the transport system for branched-chain amino acids
AS54_2155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS54_2158	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS54_2160	COG1876	peptidase activity
AS54_2162	COG0154	amidase activity
AS54_2163	COG2211	Major facilitator Superfamily
AS54_2166	COG2368	4-hydroxyphenylacetate
AS54_2168	COG0196	riboflavin kinase activity
AS54_2171	COG0251	oxidation-reduction process
AS54_2177	COG1942	4-Oxalocrotonate Tautomerase
AS54_2179	COG0561	phosphatase activity
AS54_2181	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS54_2185	COG1819	glycosyl
AS54_2186	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_2187	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_219	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS54_2193	COG0456	acetyltransferase
AS54_22	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS54_2209	COG3874	Sporulation protein YtfJ
AS54_2214	COG2226	methyltransferase
AS54_2218	COG1082	Xylose isomerase domain protein TIM barrel
AS54_2219	COG0346	lactoylglutathione lyase activity
AS54_2222	COG1595	DNA-templated transcription, initiation
AS54_2225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS54_2225	COG0426	domain, Protein
AS54_2227	COG0386	Belongs to the glutathione peroxidase family
AS54_2228	COG1305	Transglutaminase-like
AS54_2229	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS54_2230	COG0714	Associated with various cellular activities
AS54_2233	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS54_2234	COG1140	nitrate reductase beta subunit
AS54_2235	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS54_2236	COG2181	nitrate reductase activity
AS54_2237	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS54_2238	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS54_2239	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS54_224	COG0201	protein transport
AS54_2240	COG0303	'Molybdopterin
AS54_2241	COG0314	molybdopterin synthase activity
AS54_2243	COG2223	nitrite transmembrane transporter activity
AS54_2245	COG1648	precorrin-2 dehydrogenase activity
AS54_2247	COG1587	Uroporphyrinogen-III synthase
AS54_2247	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS54_2248	COG2146	nitrite reductase [NAD(P)H] activity
AS54_2249	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS54_2250	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AS54_2257	COG2359	stage V sporulation protein S
AS54_226	COG0024	Methionine aminopeptidase
AS54_2265	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS54_2270	COG1418	mRNA catabolic process
AS54_2271	COG0488	(ABC) transporter
AS54_2274	COG0629	single-stranded DNA binding
AS54_2277	COG1413	lyase activity
AS54_228	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS54_2280	COG2521	methyltransferase
AS54_2280	COG2136	Putative SAM-dependent methyltransferase
AS54_2288	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS54_2289	COG0017	Asparaginyl-tRNA synthetase
AS54_2293	COG1674	ftsk spoiiie
AS54_23	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS54_2311	COG1929	Belongs to the glycerate kinase type-1 family
AS54_2312	COG0471	metal ion transport
AS54_2313	COG0745	RESPONSE REGULATOR receiver
AS54_2314	COG3850	Histidine kinase
AS54_2314	COG5002	protein histidine kinase activity
AS54_2317	COG0733	neurotransmitter:sodium symporter activity
AS54_2322	COG2610	gluconate transmembrane transporter activity
AS54_2323	COG1454	alcohol dehydrogenase
AS54_2324	COG1794	racemase activity, acting on amino acids and derivatives
AS54_2326	COG0456	acetyltransferase
AS54_2327	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AS54_2329	COG1131	(ABC) transporter
AS54_2330	COG4473	ABC transporter
AS54_2332	COG0546	phosphoglycolate phosphatase activity
AS54_2336	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS54_234	COG1122	ATPase activity
AS54_2340	COG0768	penicillin binding
AS54_2342	COG0204	Acyl-transferase
AS54_2343	COG1272	protein, Hemolysin III
AS54_2345	COG0805	protein transport
AS54_2347	COG1307	EDD domain protein, DegV family
AS54_2348	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS54_2349	COG1999	signal sequence binding
AS54_235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS54_2350	COG0071	Belongs to the small heat shock protein (HSP20) family
AS54_2351	COG0367	asparagine synthase
AS54_2355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_2356	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS54_236	COG0101	tRNA pseudouridine synthase activity
AS54_2360	COG1335	isochorismatase
AS54_2361	COG1051	belongs to the nudix hydrolase family
AS54_2363	COG0668	transmembrane transport
AS54_2364	COG2203	Gaf domain
AS54_2364	COG4585	Histidine kinase
AS54_2365	COG2197	response regulator
AS54_2366	COG1737	Transcriptional regulator
AS54_2367	COG1064	alcohol dehydrogenase
AS54_2378	COG0517	IMP dehydrogenase activity
AS54_2378	COG1125	glycine betaine transport
AS54_2379	COG1174	glycine betaine transport
AS54_2386	COG1253	flavin adenine dinucleotide binding
AS54_2387	COG1012	belongs to the aldehyde dehydrogenase family
AS54_2388	COG5506	Protein of unknown function (DUF1694)
AS54_2391	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS54_2392	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS54_2393	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS54_2394	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS54_2395	COG0456	acetyltransferase
AS54_2396	COG3829	transcription factor binding
AS54_2397	COG1509	lysine 2,3-aminomutase activity
AS54_240	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS54_2404	COG3064	Membrane
AS54_2404	COG4991	sh3 domain protein
AS54_2404	COG0515	serine threonine protein kinase
AS54_2405	COG4326	sporulation control protein
AS54_2406	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS54_2407	COG0671	phosphoesterase, PA-phosphatase related
AS54_2408	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS54_241	COG0489	protein tyrosine kinase activity
AS54_2420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS54_2427	COG0300	oxidoreductase activity
AS54_243	COG2194	sulfuric ester hydrolase activity
AS54_2431	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS54_2431	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS54_2432	COG2814	Major facilitator Superfamily
AS54_2433	COG2814	Major facilitator Superfamily
AS54_2434	COG4841	protein insertion into membrane
AS54_2435	COG0372	Belongs to the citrate synthase family
AS54_2436	COG2079	MmgE PrpD family protein
AS54_2437	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS54_2438	COG1960	acyl-CoA dehydrogenase activity
AS54_2439	COG2084	Dehydrogenase
AS54_244	COG0726	polysaccharide deacetylase
AS54_2441	COG1280	lysine exporter protein (LysE YggA)
AS54_2442	COG1024	Enoyl-CoA hydratase
AS54_2445	COG0420	3'-5' exonuclease activity
AS54_2446	COG0419	ATPase involved in DNA repair
AS54_2450	COG2223	nitrite transmembrane transporter activity
AS54_2451	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_2452	COG1169	isochorismate synthase
AS54_2453	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS54_2454	COG3433	isochorismatase activity
AS54_2454	COG1535	isochorismatase
AS54_2455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS54_2456	COG3251	PFAM MbtH domain protein
AS54_2457	COG2814	Major facilitator Superfamily
AS54_2460	COG0776	regulation of translation
AS54_2462	COG2318	DinB family
AS54_2464	COG1115	amino acid carrier protein
AS54_2467	COG2329	Antibiotic biosynthesis monooxygenase
AS54_2468	COG1187	pseudouridine synthase activity
AS54_2469	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS54_2471	COG1136	(ABC) transporter
AS54_2473	COG0596	Alpha beta hydrolase
AS54_2474	COG2814	Major facilitator Superfamily
AS54_2478	COG2226	methyltransferase
AS54_2488	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_2495	COG1247	-acetyltransferase
AS54_2503	COG2226	methyltransferase
AS54_2504	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_2506	COG1278	Cold shock
AS54_2509	COG0010	Belongs to the arginase family
AS54_2511	COG0583	DNA-binding transcription factor activity
AS54_2512	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS54_2515	COG0583	DNA-binding transcription factor activity
AS54_2516	COG2258	MOSC domain
AS54_2519	COG1132	(ABC) transporter
AS54_2520	COG1132	(ABC) transporter
AS54_2524	COG1396	sequence-specific DNA binding
AS54_2530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS54_2533	COG1595	DNA-templated transcription, initiation
AS54_2538	COG1649	PFAM Uncharacterised BCR, COG1649
AS54_2543	COG2971	BadF BadG BcrA BcrD
AS54_2545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS54_2550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_2555	COG1309	transcriptional regulator
AS54_2558	COG0577	efflux transmembrane transporter activity
AS54_2558	COG1136	(ABC) transporter
AS54_2559	COG3615	Tellurite resistance protein tehB
AS54_2559	COG0500	methyltransferase
AS54_2561	COG3961	Belongs to the TPP enzyme family
AS54_2562	COG0582	viral genome integration into host DNA
AS54_2576	COG3961	Belongs to the TPP enzyme family
AS54_2578	COG1846	Transcriptional regulator
AS54_2585	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS54_2588	COG0110	maltose O-acetyltransferase activity
AS54_2589	COG1686	Belongs to the peptidase S11 family
AS54_2591	COG0768	penicillin binding
AS54_2592	COG1595	DNA-templated transcription, initiation
AS54_2594	COG0768	penicillin binding
AS54_2596	COG2367	Beta-lactamase
AS54_2598	COG1609	Transcriptional regulator
AS54_2599	COG2814	Major facilitator Superfamily
AS54_260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS54_2600	COG0673	inositol 2-dehydrogenase activity
AS54_2606	COG3718	enzyme involved in inositol metabolism
AS54_261	COG4856	YbbR-like protein
AS54_2611	COG0737	Belongs to the 5'-nucleotidase family
AS54_2613	COG0457	Tetratricopeptide repeat
AS54_2614	COG1476	TRANSCRIPTIONal
AS54_2617	COG1876	peptidase activity
AS54_2621	COG1309	transcriptional regulator
AS54_2624	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_2627	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_2631	COG1960	acyl-CoA dehydrogenase activity
AS54_2632	COG0439	Biotin carboxylase
AS54_2633	COG0511	ligase activity, forming carbon-carbon bonds
AS54_2634	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS54_2635	COG1024	Enoyl-CoA hydratase
AS54_2636	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS54_2637	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS54_2640	COG0572	uridine kinase
AS54_2643	COG2318	DinB family
AS54_2644	COG1686	Belongs to the peptidase S11 family
AS54_2648	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS54_2652	COG3227	Zinc metalloprotease (Elastase)
AS54_2656	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS54_2656	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS54_2661	COG2814	Major facilitator Superfamily
AS54_2663	COG2226	methyltransferase
AS54_2670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_2679	COG3386	PFAM SMP-30 Gluconolaconase
AS54_2681	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AS54_2682	COG3773	Cell wall hydrolase
AS54_2684	COG0745	RESPONSE REGULATOR receiver
AS54_2685	COG2205	protein histidine kinase activity
AS54_269	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS54_2691	COG1136	(ABC) transporter
AS54_2692	COG0577	efflux transmembrane transporter activity
AS54_2696	COG0460	homoserine dehydrogenase
AS54_2697	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_2699	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS54_27	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS54_270	COG1506	peptidase
AS54_270	COG4946	Tricorn protease homolog
AS54_270	COG0823	Involved in the tonB-independent uptake of proteins
AS54_2716	COG2124	cytochrome p450
AS54_2723	COG0561	phosphatase activity
AS54_2724	COG5002	protein histidine kinase activity
AS54_2726	COG1819	glycosyl
AS54_2727	COG1794	racemase activity, acting on amino acids and derivatives
AS54_2732	COG2205	protein histidine kinase activity
AS54_2734	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS54_2735	COG0604	alcohol dehydrogenase
AS54_2736	COG0671	phosphoesterase, PA-phosphatase related
AS54_2739	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_2741	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS54_2747	COG0693	protein deglycase activity
AS54_2750	COG2814	Major facilitator Superfamily
AS54_2754	COG0584	glycerophosphoryl diester phosphodiesterase
AS54_2757	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_2758	COG0697	spore germination
AS54_276	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_2765	COG2223	nitrite transmembrane transporter activity
AS54_2766	COG2816	NAD+ diphosphatase activity
AS54_2767	COG0592	DNA-directed DNA polymerase activity
AS54_2768	COG1051	belongs to the nudix hydrolase family
AS54_277	COG2011	ABC-type metal ion transport system permease component
AS54_2773	COG0406	alpha-ribazole phosphatase activity
AS54_2775	COG3878	Protein conserved in bacteria
AS54_278	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS54_2780	COG4667	esterase of the alpha-beta hydrolase superfamily
AS54_2785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS54_2788	COG0322	excinuclease ABC activity
AS54_279	COG1464	Belongs to the NlpA lipoprotein family
AS54_2795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS54_2799	COG1011	Hydrolase
AS54_28	COG1272	protein, Hemolysin III
AS54_2803	COG1523	belongs to the glycosyl hydrolase 13 family
AS54_2804	COG3227	Zinc metalloprotease (Elastase)
AS54_2809	COG0346	lactoylglutathione lyase activity
AS54_2810	COG0201	protein transport
AS54_2812	COG0697	spore germination
AS54_2813	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_282	COG0277	FAD linked oxidase domain protein
AS54_2820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_2823	COG2959	enzyme of heme biosynthesis
AS54_2824	COG3409	Peptidoglycan-binding domain 1 protein
AS54_2824	COG3773	Cell wall hydrolase
AS54_283	COG2271	Major facilitator Superfamily
AS54_2830	COG1309	transcriptional regulator
AS54_2835	COG3284	Transcriptional regulator
AS54_2838	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_2839	COG1349	DNA-binding transcription factor activity
AS54_2843	COG1959	2 iron, 2 sulfur cluster binding
AS54_2846	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS54_2847	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS54_2848	COG0022	dehydrogenase e1 component
AS54_2849	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS54_285	COG2814	Major facilitator Superfamily
AS54_2851	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_2852	COG0456	acetyltransferase
AS54_2852	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS54_2853	COG0572	uridine kinase
AS54_2855	COG0494	nUDIX hydrolase
AS54_2860	COG4176	ABC-type proline glycine betaine transport system permease component
AS54_2861	COG4175	Glycine betaine
AS54_2861	COG0517	IMP dehydrogenase activity
AS54_2863	COG0740	serine-type endopeptidase activity
AS54_2866	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AS54_2867	COG2153	protein acetylation
AS54_2868	COG3397	chitin binding
AS54_2870	COG2205	protein histidine kinase activity
AS54_2871	COG2226	methyltransferase
AS54_2872	COG2315	Protein conserved in bacteria
AS54_2873	COG2153	protein acetylation
AS54_2874	COG2333	competence protein COMEC
AS54_2874	COG0658	competence protein
AS54_288	COG0601	transmembrane transport
AS54_2884	COG3973	AAA domain
AS54_2887	COG2105	PFAM AIG2 family protein
AS54_2888	COG0514	ATP-dependent DNA helicase (RecQ)
AS54_289	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS54_2892	COG4637	Psort location Cytoplasmic, score
AS54_2897	COG3397	chitin binding
AS54_2899	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS54_290	COG0444	Belongs to the ABC transporter superfamily
AS54_2900	COG1115	amino acid carrier protein
AS54_2901	COG1012	belongs to the aldehyde dehydrogenase family
AS54_2902	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS54_2904	COG3938	Belongs to the proline racemase family
AS54_2905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS54_291	COG4608	Belongs to the ABC transporter superfamily
AS54_2913	COG0586	Pfam SNARE associated Golgi protein
AS54_2916	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS54_2917	COG0519	Catalyzes the synthesis of GMP from XMP
AS54_2918	COG4166	transmembrane transport
AS54_292	COG4166	transmembrane transport
AS54_2920	COG4948	Mandelate Racemase Muconate Lactonizing
AS54_2929	COG2936	dipeptidyl-peptidase activity
AS54_2930	COG5002	protein histidine kinase activity
AS54_2931	COG0745	RESPONSE REGULATOR receiver
AS54_2937	COG1164	Oligoendopeptidase f
AS54_2938	COG0531	amino acid
AS54_2939	COG1522	sequence-specific DNA binding
AS54_294	COG2207	Transcriptional regulator
AS54_2940	COG1307	EDD domain protein, DegV family
AS54_2947	COG2814	Major facilitator Superfamily
AS54_2949	COG1664	Polymer-forming cytoskeletal
AS54_2950	COG0789	Transcriptional regulator
AS54_2951	COG4533	DNA binding
AS54_2952	COG2814	Major facilitator Superfamily
AS54_2952	COG0477	Major facilitator Superfamily
AS54_2956	COG2261	transglycosylase associated protein
AS54_2959	COG2226	methyltransferase
AS54_296	COG1309	transcriptional regulator
AS54_2965	COG0436	Aminotransferase
AS54_2966	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS54_2967	COG5146	pantothenate kinase activity
AS54_2968	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS54_2971	COG1131	(ABC) transporter
AS54_2979	COG0628	permease
AS54_298	COG4166	transmembrane transport
AS54_2981	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS54_2982	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS54_2983	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS54_299	COG4166	transmembrane transport
AS54_2990	COG2746	aminoglycoside 3-N-acetyltransferase activity
AS54_2995	COG0697	spore germination
AS54_2996	COG2318	DinB family
AS54_300	COG0656	L-ascorbic acid biosynthetic process
AS54_3004	COG0861	Integral membrane protein TerC family
AS54_3005	COG1368	sulfuric ester hydrolase activity
AS54_3006	COG0488	(ABC) transporter
AS54_3008	COG2409	Drug exporters of the RND superfamily
AS54_3008	COG1033	growth of symbiont in host cell
AS54_3009	COG1309	transcriptional regulator
AS54_3012	COG0287	Prephenate dehydrogenase
AS54_3013	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS54_3015	COG1605	Chorismate mutase
AS54_3015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS54_3023	COG1388	LysM domain
AS54_3023	COG3584	3D domain protein
AS54_3025	COG2610	gluconate transmembrane transporter activity
AS54_3026	COG1024	Enoyl-CoA hydratase
AS54_3028	COG3290	protein histidine kinase activity
AS54_3028	COG3829	transcription factor binding
AS54_3032	COG1879	ABC-type sugar transport system periplasmic component
AS54_3034	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS54_3036	COG2390	Transcriptional regulator
AS54_3037	COG1070	Carbohydrate kinase
AS54_304	COG4149	molybdate abc transporter
AS54_3044	COG2329	Antibiotic biosynthesis monooxygenase
AS54_3048	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_305	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS54_3051	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS54_3052	COG4187	Peptidase family M20/M25/M40
AS54_3053	COG1414	Transcriptional regulator
AS54_3054	COG0833	amino acid
AS54_3055	COG1690	Belongs to the RtcB family
AS54_3056	COG3239	Fatty acid desaturase
AS54_3057	COG1785	Belongs to the alkaline phosphatase family
AS54_3059	COG3655	Transcriptional regulator
AS54_306	COG1910	domain protein
AS54_3062	COG4377	Putative membrane peptidase family (DUF2324)
AS54_3064	COG3279	Response regulator of the LytR AlgR family
AS54_3066	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_3067	COG0346	lactoylglutathione lyase activity
AS54_3072	COG0714	Associated with various cellular activities
AS54_3081	COG0463	Glycosyl transferase, family 2
AS54_3083	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS54_3084	COG0753	catalase activity
AS54_3086	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS54_3093	COG0778	Nitroreductase
AS54_3094	COG1846	Transcriptional regulator
AS54_310	COG0697	spore germination
AS54_3102	COG1725	Transcriptional regulator
AS54_3105	COG1136	(ABC) transporter
AS54_3105	COG0577	efflux transmembrane transporter activity
AS54_3110	COG2207	Transcriptional regulator
AS54_3111	COG0456	acetyltransferase
AS54_3115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_3120	COG0642	Histidine kinase
AS54_3121	COG0745	RESPONSE REGULATOR receiver
AS54_3122	COG0596	Alpha beta hydrolase
AS54_3128	COG0730	response to heat
AS54_313	COG0204	Acyl-transferase
AS54_3130	COG0833	amino acid
AS54_3132	COG4335	DNA alkylation repair
AS54_3141	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS54_3147	COG1984	allophanate hydrolase subunit 2
AS54_3148	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS54_3149	COG1414	Transcriptional regulator
AS54_315	COG1609	Transcriptional regulator
AS54_3151	COG3142	Participates in the control of copper homeostasis
AS54_3152	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS54_3153	COG0640	Transcriptional regulator
AS54_3155	COG1960	acyl-CoA dehydrogenase activity
AS54_3164	COG3848	Pyruvate phosphate dikinase
AS54_3164	COG0574	Belongs to the PEP-utilizing enzyme family
AS54_3166	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_3169	COG5577	PFAM Coat F domain
AS54_317	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_3171	COG3403	YqcI/YcgG family
AS54_3172	COG1280	lysine exporter protein (LysE YggA)
AS54_3173	COG1113	amino acid transport
AS54_3179	COG1063	alcohol dehydrogenase
AS54_3182	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS54_3185	COG0737	Belongs to the 5'-nucleotidase family
AS54_3186	COG2329	Antibiotic biosynthesis monooxygenase
AS54_3188	COG0598	Magnesium transport protein CorA
AS54_3193	COG1063	alcohol dehydrogenase
AS54_3195	COG2124	cytochrome p450
AS54_3196	COG1309	transcriptional regulator
AS54_320	COG0084	hydrolase, TatD family'
AS54_3201	COG0415	Belongs to the DNA photolyase family
AS54_3202	COG0288	reversible hydration of carbon dioxide
AS54_3204	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS54_3205	COG5609	conserved protein (DUF2294)
AS54_3208	COG0714	Associated with various cellular activities
AS54_3209	COG1575	Belongs to the MenA family. Type 1 subfamily
AS54_3210	COG2267	carboxylic ester hydrolase activity
AS54_3211	COG4641	Protein conserved in bacteria
AS54_3213	COG1136	(ABC) transporter
AS54_3214	COG0577	efflux transmembrane transporter activity
AS54_3217	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS54_3218	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS54_3219	COG1121	(ABC) transporter
AS54_322	COG5298	Protein conserved in bacteria
AS54_3224	COG0798	PFAM Bile acid sodium symporter
AS54_3225	COG0346	lactoylglutathione lyase activity
AS54_3226	COG0640	Transcriptional regulator
AS54_3230	COG0443	Heat shock 70 kDa protein
AS54_3234	COG0346	lactoylglutathione lyase activity
AS54_3242	COG2814	Major facilitator Superfamily
AS54_3247	COG0745	RESPONSE REGULATOR receiver
AS54_3248	COG5002	protein histidine kinase activity
AS54_3248	COG3850	Histidine kinase
AS54_3253	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AS54_3258	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_3259	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS54_326	COG0488	(ABC) transporter
AS54_3261	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_3264	COG2309	aminopeptidase activity
AS54_3267	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS54_3271	COG0653	protein targeting
AS54_3274	COG0577	efflux transmembrane transporter activity
AS54_3277	COG5002	protein histidine kinase activity
AS54_3277	COG3850	Histidine kinase
AS54_3279	COG2364	Membrane
AS54_328	COG0747	negative chemotaxis
AS54_3280	COG1846	Transcriptional regulator
AS54_3281	COG0456	acetyltransferase
AS54_3282	COG2808	Putative FMN-binding domain
AS54_3283	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_3284	COG2271	Major facilitator Superfamily
AS54_3285	COG1556	Lactate utilization protein
AS54_3286	COG1139	Iron-sulfur cluster binding protein
AS54_3288	COG0583	DNA-binding transcription factor activity
AS54_329	COG0601	transmembrane transport
AS54_3293	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS54_3296	COG1252	NADH dehydrogenase
AS54_3297	COG3227	Zinc metalloprotease (Elastase)
AS54_3298	COG0584	glycerophosphoryl diester phosphodiesterase
AS54_33	COG1164	Oligoendopeptidase f
AS54_330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS54_3308	COG0738	Major facilitator superfamily
AS54_3309	COG0673	inositol 2-dehydrogenase activity
AS54_331	COG0444	Belongs to the ABC transporter superfamily
AS54_3310	COG0561	phosphatase activity
AS54_3311	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS54_3312	COG1609	Transcriptional regulator
AS54_3313	COG0457	Tetratricopeptide repeat
AS54_332	COG4608	Belongs to the ABC transporter superfamily
AS54_3320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS54_3324	COG0814	amino acid
AS54_3325	COG1760	l-serine dehydratase
AS54_3326	COG1760	l-serine dehydratase
AS54_3327	COG2184	nucleotidyltransferase activity
AS54_3328	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS54_3329	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AS54_333	COG0561	phosphatase activity
AS54_3331	COG1335	isochorismatase
AS54_3332	COG1522	sequence-specific DNA binding
AS54_3333	COG0531	amino acid
AS54_3337	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS54_3341	COG1595	DNA-templated transcription, initiation
AS54_3344	COG0662	Cupin 2, conserved barrel domain protein
AS54_3345	COG2207	Transcriptional regulator
AS54_3345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_3351	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS54_3351	COG3409	Peptidoglycan-binding domain 1 protein
AS54_3354	COG2814	Major facilitator Superfamily
AS54_3362	COG0477	Major facilitator Superfamily
AS54_3364	COG1846	Transcriptional regulator
AS54_3365	COG2814	Major facilitator Superfamily
AS54_3368	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS54_3369	COG1131	(ABC) transporter
AS54_3373	COG2076	Multidrug Resistance protein
AS54_3374	COG1309	transcriptional regulator
AS54_3377	COG2031	fatty acid transporter
AS54_3379	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS54_3385	COG1122	ATPase activity
AS54_3386	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS54_339	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS54_3390	COG1288	antiporter activity
AS54_3391	COG2356	endonuclease I
AS54_3392	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS54_3394	COG2197	response regulator
AS54_3398	COG1733	regulation of RNA biosynthetic process
AS54_3399	COG0778	Nitroreductase
AS54_340	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS54_3403	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_3405	COG1131	(ABC) transporter
AS54_3410	COG1011	Hydrolase
AS54_3419	COG0346	lactoylglutathione lyase activity
AS54_342	COG2814	Major facilitator Superfamily
AS54_3420	COG1940	carbohydrate kinase activity
AS54_3421	COG0738	Major facilitator superfamily
AS54_3422	COG0110	maltose O-acetyltransferase activity
AS54_3424	COG1136	(ABC) transporter
AS54_3424	COG0577	efflux transmembrane transporter activity
AS54_3426	COG0180	Tryptophanyl-tRNA synthetase
AS54_3428	COG0628	permease
AS54_3432	COG2226	methyltransferase
AS54_3434	COG0477	Major facilitator Superfamily
AS54_344	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS54_3440	COG1253	flavin adenine dinucleotide binding
AS54_3441	COG0789	Transcriptional regulator
AS54_3442	COG0697	spore germination
AS54_3443	COG1357	PFAM Pentapeptide repeats (8 copies)
AS54_3445	COG2706	6-phosphogluconolactonase activity
AS54_3446	COG1070	Carbohydrate kinase
AS54_3448	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS54_3449	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS54_3451	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS54_3456	COG0814	amino acid
AS54_346	COG0705	Rhomboid family
AS54_346	COG0457	Tetratricopeptide repeat
AS54_3461	COG1393	Belongs to the ArsC family
AS54_3462	COG2188	Transcriptional regulator
AS54_3463	COG0673	inositol 2-dehydrogenase activity
AS54_3466	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_347	COG4294	response to UV
AS54_3470	COG0384	phenazine biosynthesis protein PhzF
AS54_3472	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_3475	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_3476	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS54_3477	COG1733	regulation of RNA biosynthetic process
AS54_3481	COG0726	polysaccharide deacetylase
AS54_3483	COG1191	sigma factor activity
AS54_3484	COG1266	CAAX protease self-immunity
AS54_3485	COG1309	transcriptional regulator
AS54_3489	COG3152	Membrane
AS54_349	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS54_3498	COG1151	hydroxylamine reductase activity
AS54_350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS54_3500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_3501	COG3409	Peptidoglycan-binding domain 1 protein
AS54_3501	COG3757	hydrolase, family 25
AS54_3508	COG2072	flavoprotein involved in K transport
AS54_351	COG0864	Transcriptional regulator
AS54_3514	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_3517	COG1695	Transcriptional regulator
AS54_3519	COG1113	amino acid transport
AS54_352	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS54_3520	COG2814	Major facilitator Superfamily
AS54_3526	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS54_3527	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS54_353	COG2183	response to ionizing radiation
AS54_3530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_3531	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_3532	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_3533	COG3739	integral membrane protein
AS54_3534	COG0384	phenazine biosynthesis protein PhzF
AS54_3538	COG0583	DNA-binding transcription factor activity
AS54_3542	COG1193	negative regulation of DNA recombination
AS54_3547	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS54_3548	COG1164	Oligoendopeptidase f
AS54_3549	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS54_3555	COG0584	glycerophosphoryl diester phosphodiesterase
AS54_3560	COG0640	Transcriptional regulator
AS54_3561	COG0604	alcohol dehydrogenase
AS54_3563	COG0457	Tetratricopeptide repeat
AS54_3565	COG2808	Putative FMN-binding domain
AS54_3566	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS54_3568	COG0385	Bile acid
AS54_3569	COG0277	FAD linked oxidase domain protein
AS54_3575	COG1216	Glycosyl transferase, family 2
AS54_3576	COG1024	Enoyl-CoA hydratase
AS54_3578	COG1285	pathogenesis
AS54_3581	COG2514	catechol 2,3-dioxygenase activity
AS54_3582	COG2720	vancomycin resistance protein
AS54_3588	COG1278	Cold shock
AS54_3590	COG0716	FMN binding
AS54_3598	COG2801	Transposase and inactivated derivatives
AS54_3602	COG0739	heme binding
AS54_3603	COG0741	lytic transglycosylase activity
AS54_3604	COG3757	hydrolase, family 25
AS54_3604	COG3409	Peptidoglycan-binding domain 1 protein
AS54_3614	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_3616	COG0165	Argininosuccinate lyase
AS54_3619	COG4145	pantothenate transmembrane transporter activity
AS54_3621	COG1012	belongs to the aldehyde dehydrogenase family
AS54_3622	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_3624	COG1657	PFAM Prenyltransferase squalene oxidase
AS54_3625	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AS54_3626	COG2962	Rard protein
AS54_3627	COG3326	Membrane
AS54_3630	COG0489	protein tyrosine kinase activity
AS54_3632	COG0314	molybdopterin synthase activity
AS54_3633	COG0303	'Molybdopterin
AS54_3634	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS54_3635	COG2116	formate transmembrane transporter activity
AS54_3637	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS54_3638	COG5609	conserved protein (DUF2294)
AS54_3639	COG2427	Protein of unknown function (DUF1641)
AS54_3640	COG3383	formate dehydrogenase (NAD+) activity
AS54_3642	COG0697	spore germination
AS54_3650	COG2226	methyltransferase
AS54_3651	COG4166	transmembrane transport
AS54_3652	COG4166	transmembrane transport
AS54_3653	COG4166	transmembrane transport
AS54_3654	COG1301	dicarboxylic acid transport
AS54_3655	COG1316	TRANSCRIPTIONal
AS54_3657	COG1595	DNA-templated transcription, initiation
AS54_3659	COG1131	(ABC) transporter
AS54_3661	COG0673	inositol 2-dehydrogenase activity
AS54_3663	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS54_3664	COG0187	DNA topoisomerase II activity
AS54_3665	COG1832	CoA-binding protein
AS54_3666	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS54_3667	COG0745	RESPONSE REGULATOR receiver
AS54_3671	COG4841	protein insertion into membrane
AS54_3672	COG0824	Thioesterase
AS54_3678	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS54_3680	COG2274	protein secretion by the type I secretion system
AS54_3681	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS54_3683	COG0726	polysaccharide deacetylase
AS54_3687	COG2211	Major facilitator Superfamily
AS54_3689	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS54_3692	COG0183	Belongs to the thiolase family
AS54_3693	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_3694	COG1268	BioY protein
AS54_3695	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_37	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS54_3706	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_3708	COG5002	protein histidine kinase activity
AS54_3709	COG0400	carboxylic ester hydrolase activity
AS54_3710	COG0346	lactoylglutathione lyase activity
AS54_3711	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS54_3712	COG0069	glutamate synthase activity
AS54_3713	COG1902	pentaerythritol trinitrate reductase activity
AS54_3714	COG1329	Transcriptional regulator
AS54_3715	COG0010	Belongs to the arginase family
AS54_372	COG0802	atpase or kinase
AS54_3720	COG2226	methyltransferase
AS54_3728	COG4846	Membrane protein involved in cytochrome C biogenesis
AS54_3729	COG0785	Cytochrome C biogenesis protein
AS54_373	COG1214	PFAM Peptidase M22, glycoprotease
AS54_3733	COG1131	(ABC) transporter
AS54_3735	COG0583	DNA-binding transcription factor activity
AS54_3737	COG1346	cytolysis
AS54_374	COG0456	acetyltransferase
AS54_3740	COG0730	response to heat
AS54_3742	COG3409	Peptidoglycan-binding domain 1 protein
AS54_3742	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS54_3745	COG1132	(ABC) transporter
AS54_3746	COG1132	(ABC) transporter
AS54_3751	COG3639	organic phosphonate transmembrane transporter activity
AS54_3754	COG0737	Belongs to the 5'-nucleotidase family
AS54_3756	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS54_376	COG0488	(ABC) transporter
AS54_3760	COG1695	Transcriptional regulator
AS54_3761	COG0174	glutamine synthetase
AS54_3762	COG0789	Transcriptional regulator
AS54_3763	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS54_3764	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS54_3765	COG2860	membrane
AS54_3767	COG0464	growth
AS54_3773	COG3584	3D domain protein
AS54_3773	COG1388	LysM domain
AS54_3774	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS54_3774	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS54_3774	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS54_3775	COG1105	Belongs to the carbohydrate kinase PfkB family
AS54_3776	COG1349	DNA-binding transcription factor activity
AS54_3777	COG1979	alcohol dehydrogenase
AS54_3778	COG2322	membrane
AS54_3781	COG1113	amino acid transport
AS54_3784	COG1408	metallophosphoesterase
AS54_3785	COG2116	formate transmembrane transporter activity
AS54_379	COG1266	CAAX protease self-immunity
AS54_3790	COG2217	Heavy metal translocating P-type atpase
AS54_3791	COG2608	mercury ion transmembrane transporter activity
AS54_3792	COG1937	Protein conserved in bacteria
AS54_3794	COG2819	hydrolase of the alpha beta superfamily
AS54_3795	COG1120	ATPase activity
AS54_3796	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_3797	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_3798	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_3799	COG0708	Exodeoxyribonuclease III
AS54_38	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS54_3800	COG2169	Transcriptional regulator
AS54_3801	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS54_3802	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS54_3804	COG2364	Membrane
AS54_3807	COG2267	carboxylic ester hydrolase activity
AS54_3808	COG0346	lactoylglutathione lyase activity
AS54_3809	COG3300	MHYT domain
AS54_3809	COG5001	Diguanylate cyclase
AS54_3813	COG1086	Polysaccharide biosynthesis protein
AS54_3819	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_382	COG5444	nuclease activity
AS54_3822	COG1404	Belongs to the peptidase S8 family
AS54_3823	COG3773	Cell wall hydrolase
AS54_3825	COG1368	sulfuric ester hydrolase activity
AS54_3826	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS54_3828	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AS54_3832	COG4550	Control of competence regulator ComK, YlbF/YmcA
AS54_3834	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS54_3835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS54_3835	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS54_3837	COG2359	stage V sporulation protein S
AS54_3838	COG1692	metallophosphoesterase
AS54_3842	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS54_3843	COG1426	Protein conserved in bacteria
AS54_3846	COG0300	oxidoreductase activity
AS54_3847	COG0612	Peptidase, M16
AS54_3848	COG0612	Peptidase, M16
AS54_385	COG2252	PERMEase
AS54_3853	COG2188	Transcriptional regulator
AS54_3854	COG1674	ftsk spoiiie
AS54_3856	COG0740	serine-type endopeptidase activity
AS54_3857	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS54_3859	COG0527	aspartate kinase activity
AS54_3860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS54_3861	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS54_3862	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS54_3863	COG1873	PFAM PRC-barrel domain
AS54_3864	COG0612	Peptidase, M16
AS54_3865	COG0726	polysaccharide deacetylase
AS54_3868	COG0196	riboflavin kinase activity
AS54_387	COG5002	protein histidine kinase activity
AS54_3871	COG1550	Protein conserved in bacteria
AS54_3873	COG1358	cellular component organization or biogenesis
AS54_3874	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS54_3875	COG0195	Participates in both transcription termination and antitermination
AS54_3882	COG0750	zinc metalloprotease
AS54_3884	COG4589	Belongs to the CDS family
AS54_3887	COG0528	UMP kinase activity
AS54_3893	COG4974	Belongs to the 'phage' integrase family
AS54_3895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS54_3896	COG0758	DNA mediated transformation
AS54_3897	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS54_39	COG4853	Protein conserved in bacteria
AS54_3905	COG1837	Belongs to the UPF0109 family
AS54_3907	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS54_3909	COG0552	protein localization to endoplasmic reticulum
AS54_3910	COG1196	nuclear chromosome segregation
AS54_3913	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_3914	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS54_3917	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS54_3918	COG1461	Dihydroxyacetone kinase
AS54_3919	COG1302	Protein conserved in bacteria
AS54_3921	COG1564	THIamine pyrophosphokinase
AS54_3922	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS54_3923	COG1162	GTPase activity
AS54_3924	COG0515	serine threonine protein kinase
AS54_3924	COG2815	serine threonine protein kinase
AS54_3925	COG0631	protein serine/threonine phosphatase activity
AS54_3927	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS54_3927	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS54_3929	COG0242	peptide deformylase activity
AS54_393	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS54_3930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS54_3931	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS54_3933	COG0194	GDP metabolic process
AS54_3935	COG1561	YicC-like family, N-terminal region
AS54_3936	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS54_3938	COG0006	proline dipeptidase activity
AS54_3942	COG3069	C4-dicarboxylate transmembrane transporter activity
AS54_3950	COG0505	Belongs to the CarA family
AS54_3955	COG0564	pseudouridine synthase activity
AS54_3959	COG3599	regulation of cell shape
AS54_3960	COG2302	S4 RNA-binding domain
AS54_3961	COG0762	integral membrane protein
AS54_3963	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS54_3965	COG1873	PFAM PRC-barrel domain
AS54_3966	COG1191	sigma factor activity
AS54_3967	COG1191	sigma factor activity
AS54_3969	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS54_3970	COG0849	cell division
AS54_3971	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS54_3972	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS54_3973	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS54_3974	COG0772	Belongs to the SEDS family
AS54_3977	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS54_3978	COG0768	penicillin binding
AS54_3980	COG4839	cell division protein FtsL
AS54_3983	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS54_3987	COG1399	metal-binding, possibly nucleic acid-binding protein
AS54_3989	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS54_3990	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS54_3992	COG3314	Sporulation integral membrane protein YlbJ
AS54_3993	COG0742	ribosomal rna small subunit methyltransferase
AS54_3996	COG3679	Belongs to the UPF0342 family
AS54_3997	COG0406	alpha-ribazole phosphatase activity
AS54_4	COG1607	acyl-coa hydrolase
AS54_40	COG4863	YycH protein
AS54_4000	COG2340	Cysteine-rich secretory protein family
AS54_4003	COG3336	cytochrome c oxidase
AS54_4010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS54_4011	COG0772	Belongs to the SEDS family
AS54_4013	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS54_4014	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS54_4016	COG4896	Protein conserved in bacteria
AS54_4021	COG0483	inositol monophosphate 1-phosphatase activity
AS54_4025	COG1982	Orn Lys Arg decarboxylase major
AS54_4035	COG0022	dehydrogenase e1 component
AS54_4036	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS54_4038	COG0242	peptide deformylase activity
AS54_4039	COG0561	phosphatase activity
AS54_4041	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS54_4042	COG0569	domain protein
AS54_4046	COG0583	DNA-binding transcription factor activity
AS54_4047	COG0517	IMP dehydrogenase activity
AS54_4049	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AS54_4051	COG4703	Protein of unknown function (DUF1797)
AS54_4054	COG2200	EAL domain
AS54_4055	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_4056	COG1408	metallophosphoesterase
AS54_4058	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AS54_406	COG2205	protein histidine kinase activity
AS54_4065	COG2814	Major facilitator Superfamily
AS54_4069	COG3209	COG3209 Rhs family protein
AS54_407	COG0745	RESPONSE REGULATOR receiver
AS54_4071	COG2205	protein histidine kinase activity
AS54_4073	COG0436	Aminotransferase
AS54_4074	COG1609	Transcriptional regulator
AS54_4075	COG3833	ABC-type maltose transport systems, permease component
AS54_4076	COG1175	transmembrane transport
AS54_4077	COG2182	Extracellular solute-binding protein
AS54_4079	COG0366	Alpha amylase catalytic
AS54_4080	COG3842	ATPase activity
AS54_4089	COG0183	Belongs to the thiolase family
AS54_4095	COG1695	Transcriptional regulator
AS54_4096	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_41	COG5002	protein histidine kinase activity
AS54_4100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS54_4101	COG0436	Aminotransferase
AS54_4108	COG2084	Dehydrogenase
AS54_4109	COG3706	GGDEF domain
AS54_4110	COG0778	Nitroreductase
AS54_4115	COG1263	PTS System
AS54_4115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_4115	COG2190	(PTS) system
AS54_4116	COG3711	transcriptional antiterminator
AS54_412	COG0697	spore germination
AS54_4120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS54_4125	COG1547	Domain of unknown function (DUF309)
AS54_4126	COG0456	acetyltransferase
AS54_4127	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS54_4128	COG4086	secreted protein
AS54_4129	COG0561	phosphatase activity
AS54_4130	COG0697	spore germination
AS54_4133	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_4138	COG0733	neurotransmitter:sodium symporter activity
AS54_4142	COG1686	Belongs to the peptidase S11 family
AS54_4143	COG1725	Transcriptional regulator
AS54_4144	COG1131	(ABC) transporter
AS54_4147	COG1846	Transcriptional regulator
AS54_4150	COG0598	Magnesium transport protein CorA
AS54_4155	COG4974	Belongs to the 'phage' integrase family
AS54_4157	COG0735	belongs to the Fur family
AS54_4158	COG1300	Membrane
AS54_4162	COG0667	Aldo Keto reductase
AS54_4163	COG0656	L-ascorbic acid biosynthetic process
AS54_4164	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS54_4164	COG0456	acetyltransferase
AS54_4166	COG4085	toxin activity
AS54_4166	COG1525	nuclease
AS54_4166	COG0737	Belongs to the 5'-nucleotidase family
AS54_4168	COG0596	Alpha beta hydrolase
AS54_4169	COG2056	Na+-H+ antiporter family
AS54_4170	COG1609	Transcriptional regulator
AS54_4171	COG0456	acetyltransferase
AS54_4172	COG1073	alpha beta
AS54_4175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS54_4175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS54_4176	COG0307	riboflavin synthase, alpha
AS54_418	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS54_4181	COG4106	trans-aconitate 2-methyltransferase activity
AS54_4182	COG2226	methyltransferase
AS54_4182	COG1073	alpha beta
AS54_4185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS54_4188	COG0737	Belongs to the 5'-nucleotidase family
AS54_419	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS54_4190	COG1522	sequence-specific DNA binding
AS54_4194	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS54_4196	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AS54_4199	COG0300	oxidoreductase activity
AS54_42	COG0745	RESPONSE REGULATOR receiver
AS54_420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS54_4200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_4201	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS54_4202	COG1760	l-serine dehydratase
AS54_4203	COG1760	l-serine dehydratase
AS54_4206	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS54_4207	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS54_4208	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_4210	COG1376	ErfK ybiS ycfS ynhG family protein
AS54_4211	COG4129	membrane
AS54_4212	COG1126	abc transporter atp-binding protein
AS54_4213	COG0765	amino acid transport
AS54_4214	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS54_4217	COG2816	NAD+ diphosphatase activity
AS54_4218	COG0772	Belongs to the SEDS family
AS54_4219	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS54_422	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS54_4220	COG0022	dehydrogenase e1 component
AS54_4221	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS54_4222	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS54_4224	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS54_4225	COG0280	phosphate acetyltransferase
AS54_4226	COG3829	transcription factor binding
AS54_4226	COG3290	protein histidine kinase activity
AS54_4228	COG0584	glycerophosphoryl diester phosphodiesterase
AS54_4229	COG3093	addiction module antidote protein HigA
AS54_4231	COG0745	RESPONSE REGULATOR receiver
AS54_4232	COG0750	zinc metalloprotease
AS54_4233	COG0497	DNA recombination
AS54_4235	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AS54_4237	COG0142	geranyltranstransferase activity
AS54_4242	COG1302	Protein conserved in bacteria
AS54_4243	COG0439	Biotin carboxylase
AS54_4244	COG0511	ligase activity, forming carbon-carbon bonds
AS54_425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AS54_4253	COG3854	ATPases associated with a variety of cellular activities
AS54_4258	COG0006	proline dipeptidase activity
AS54_4261	COG3872	metal-dependent enzyme
AS54_4262	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS54_4266	COG1695	Transcriptional regulator
AS54_4269	COG0095	Lipoate-protein ligase
AS54_427	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS54_4270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_4271	COG1609	Transcriptional regulator
AS54_4273	COG2076	Multidrug Resistance protein
AS54_4274	COG2076	Multidrug Resistance protein
AS54_4281	COG1131	(ABC) transporter
AS54_4282	COG1725	Transcriptional regulator
AS54_4288	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS54_429	COG0151	Belongs to the GarS family
AS54_4299	COG4970	Tfp pilus assembly protein FimT
AS54_4301	COG1459	type II secretion system
AS54_4302	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS54_4312	COG0646	methionine synthase
AS54_4312	COG1410	methionine synthase
AS54_4313	COG0646	methionine synthase
AS54_4313	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS54_4314	COG0626	cystathionine gamma-synthase activity
AS54_4315	COG0626	cystathionine gamma-synthase activity
AS54_4318	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_4320	COG1940	carbohydrate kinase activity
AS54_4321	COG4483	Protein conserved in bacteria
AS54_4322	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS54_4324	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS54_4325	COG0704	Plays a role in the regulation of phosphate uptake
AS54_4326	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS54_4327	COG0581	inorganic phosphate transmembrane transporter activity
AS54_4328	COG0573	inorganic phosphate transmembrane transporter activity
AS54_4329	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS54_4331	COG0477	Major facilitator Superfamily
AS54_4332	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS54_4337	COG0735	belongs to the Fur family
AS54_4338	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS54_4339	COG1121	(ABC) transporter
AS54_434	COG0210	DNA helicase
AS54_4340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_4346	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS54_4347	COG2384	SAM-dependent methyltransferase
AS54_4348	COG2010	Cytochrome c
AS54_4349	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS54_4350	COG0358	DNA primase activity
AS54_4352	COG0517	IMP dehydrogenase activity
AS54_4355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS54_4356	COG0295	cytidine deaminase activity
AS54_4357	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AS54_4359	COG1480	7TM receptor with intracellular HD hydrolase
AS54_436	COG4851	CamS sex pheromone cAM373 precursor
AS54_4360	COG1702	phosphate starvation-inducible protein PhoH
AS54_4363	COG1610	YqeY-like protein
AS54_4365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS54_4366	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS54_4370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS54_4372	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS54_4373	COG1733	regulation of RNA biosynthetic process
AS54_4378	COG1466	dna polymerase III delta subunit
AS54_4380	COG2333	competence protein COMEC
AS54_4380	COG0658	competence protein
AS54_4381	COG2131	deaminase
AS54_4382	COG1555	photosystem II stabilization
AS54_4382	COG1596	polysaccharide export
AS54_4383	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS54_4384	COG2226	methyltransferase
AS54_4385	COG0799	negative regulation of ribosome biogenesis
AS54_4386	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS54_4388	COG1534	Rna-binding protein
AS54_4390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS54_4391	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS54_4394	COG1191	sigma factor activity
AS54_4396	COG1595	DNA-templated transcription, initiation
AS54_4398	COG0778	Nitroreductase
AS54_4399	COG2357	RelA SpoT domain protein
AS54_440	COG1335	isochorismatase
AS54_4401	COG1785	Belongs to the alkaline phosphatase family
AS54_4403	COG2267	carboxylic ester hydrolase activity
AS54_441	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS54_4410	COG1404	Belongs to the peptidase S8 family
AS54_4411	COG3186	Phenylalanine-4-hydroxylase
AS54_4413	COG2514	catechol 2,3-dioxygenase activity
AS54_4414	COG2259	Doxx family
AS54_442	COG2011	ABC-type metal ion transport system permease component
AS54_4422	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_4424	COG1454	alcohol dehydrogenase
AS54_4424	COG1012	belongs to the aldehyde dehydrogenase family
AS54_4425	COG0626	cystathionine gamma-synthase activity
AS54_4426	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS54_443	COG1464	Belongs to the NlpA lipoprotein family
AS54_4431	COG0768	penicillin binding
AS54_4437	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS54_4443	COG0628	permease
AS54_4447	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS54_4450	COG1104	cysteine desulfurase activity
AS54_4451	COG1959	2 iron, 2 sulfur cluster binding
AS54_4452	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS54_4454	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS54_4456	COG0124	histidyl-tRNA synthetase
AS54_4459	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS54_446	COG0003	Pfam Anion-transporting ATPase
AS54_4461	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS54_4461	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS54_4462	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS54_4463	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS54_4463	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS54_4465	COG2244	polysaccharide biosynthetic process
AS54_4466	COG2323	membrane
AS54_4468	COG1862	Preprotein translocase
AS54_447	COG1846	Transcriptional regulator
AS54_4474	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS54_4476	COG0697	spore germination
AS54_4477	COG0697	spore germination
AS54_4478	COG0640	Transcriptional regulator
AS54_448	COG4682	membrane
AS54_4483	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS54_4484	COG1104	cysteine desulfurase activity
AS54_4485	COG1827	regulation of RNA biosynthetic process
AS54_4486	COG2258	MOSC domain
AS54_4487	COG0077	Prephenate dehydratase
AS54_4488	COG0577	efflux transmembrane transporter activity
AS54_4489	COG0577	efflux transmembrane transporter activity
AS54_4490	COG1136	(ABC) transporter
AS54_4491	COG5002	protein histidine kinase activity
AS54_4492	COG0745	RESPONSE REGULATOR receiver
AS54_4494	COG3290	protein histidine kinase activity
AS54_4496	COG2868	ribosomal protein
AS54_4498	COG1530	ribonuclease E activity
AS54_4499	COG1994	Peptidase M50
AS54_4500	COG0739	heme binding
AS54_4501	COG2894	cell division
AS54_4504	COG1792	Involved in formation and maintenance of cell shape
AS54_4505	COG1077	Cell shape determining protein MreB Mrl
AS54_4509	COG0285	dihydrofolate synthase activity
AS54_4510	COG0525	valine-tRNA ligase activity
AS54_4512	COG1388	LysM domain
AS54_4514	COG0113	porphobilinogen synthase activity
AS54_4515	COG1587	Uroporphyrinogen-III synthase
AS54_4517	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS54_4519	COG1846	Transcriptional regulator
AS54_452	COG1597	lipid kinase activity
AS54_4520	COG1764	response to oxidative stress
AS54_4523	COG1067	ATP-dependent peptidase activity
AS54_4523	COG0470	DNA polymerase III
AS54_453	COG0546	phosphoglycolate phosphatase activity
AS54_4533	COG0622	Phosphoesterase
AS54_4534	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS54_4536	COG5401	PFAM Sporulation and spore germination
AS54_454	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS54_4540	COG1309	transcriptional regulator
AS54_4543	COG2197	response regulator
AS54_4544	COG2233	PERMEase
AS54_4545	COG0402	S-adenosylhomocysteine deaminase activity
AS54_4546	COG1983	PspC domain protein
AS54_4547	COG1396	sequence-specific DNA binding
AS54_4548	COG0697	spore germination
AS54_4551	COG1959	2 iron, 2 sulfur cluster binding
AS54_4552	COG1668	transmembrane transport
AS54_4553	COG4152	abc transporter atp-binding protein
AS54_4554	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AS54_4555	COG1360	Flagellar Motor Protein
AS54_4556	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS54_4557	COG1876	peptidase activity
AS54_4558	COG0824	Thioesterase
AS54_4559	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS54_456	COG1012	belongs to the aldehyde dehydrogenase family
AS54_4560	COG1053	succinate dehydrogenase
AS54_4561	COG2009	succinate dehydrogenase
AS54_4562	COG1719	4-vinyl reductase, 4VR
AS54_4564	COG3118	belongs to the thioredoxin family
AS54_4565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS54_4566	COG2086	electron transfer activity
AS54_4567	COG1024	Enoyl-CoA hydratase
AS54_4568	COG1309	transcriptional regulator
AS54_4569	COG0318	PFAM AMP-dependent synthetase and ligase
AS54_457	COG2076	Multidrug Resistance protein
AS54_4573	COG2318	DinB family
AS54_4578	COG1131	(ABC) transporter
AS54_4579	COG2205	protein histidine kinase activity
AS54_458	COG2309	aminopeptidase activity
AS54_4580	COG0745	RESPONSE REGULATOR receiver
AS54_4582	COG4895	conserved protein (DUF2196)
AS54_4583	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS54_4586	COG4509	Sortase family
AS54_4587	COG1120	ATPase activity
AS54_4590	COG5386	Cell surface protein
AS54_4591	COG5386	Cell surface protein
AS54_4592	COG1114	Component of the transport system for branched-chain amino acids
AS54_4593	COG1187	pseudouridine synthase activity
AS54_4596	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS54_4596	COG1796	DNA polymerase
AS54_4597	COG1286	toxin biosynthetic process
AS54_4603	COG0017	Asparaginyl-tRNA synthetase
AS54_4604	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS54_4604	COG0072	phenylalanine-tRNA ligase activity
AS54_4606	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS54_4608	COG1418	mRNA catabolic process
AS54_461	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_4615	COG2814	Major facilitator Superfamily
AS54_4616	COG1566	PFAM secretion protein HlyD family protein
AS54_4617	COG1309	transcriptional regulator
AS54_4618	COG1363	Peptidase, m42
AS54_462	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS54_4622	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS54_4623	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS54_4625	COG1484	DNA-dependent DNA replication
AS54_4626	COG3611	Membrane attachment protein
AS54_4628	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AS54_4629	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS54_463	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS54_4630	COG0237	dephospho-CoA kinase activity
AS54_4631	COG1971	Probably functions as a manganese efflux pump
AS54_4632	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS54_4633	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS54_4633	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS54_4634	COG5002	protein histidine kinase activity
AS54_4635	COG0745	RESPONSE REGULATOR receiver
AS54_464	COG5002	protein histidine kinase activity
AS54_4640	COG0538	isocitrate dehydrogenase activity
AS54_4641	COG0372	Belongs to the citrate synthase family
AS54_4643	COG0628	permease
AS54_4644	COG3030	protein affecting phage T7 exclusion by the F plasmid
AS54_4649	COG1725	Transcriptional regulator
AS54_465	COG4807	Protein conserved in bacteria
AS54_4650	COG0281	malic enzyme
AS54_4651	COG0587	DNA-directed DNA polymerase activity
AS54_4654	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS54_4658	COG4109	DRTGG domain
AS54_4661	COG0006	proline dipeptidase activity
AS54_4670	COG0662	Cupin 2, conserved barrel domain protein
AS54_4672	COG1476	TRANSCRIPTIONal
AS54_4675	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_4676	COG0589	response to stress
AS54_4685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_4688	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS54_4689	COG0827	DNA restriction-modification system
AS54_4690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AS54_4691	COG3874	Sporulation protein YtfJ
AS54_4693	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS54_4694	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS54_4696	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS54_4699	COG1104	cysteine desulfurase activity
AS54_4701	COG0583	DNA-binding transcription factor activity
AS54_4702	COG0697	spore germination
AS54_4703	COG0697	spore germination
AS54_4704	COG1309	transcriptional regulator
AS54_4705	COG1956	GAF domain-containing protein
AS54_4706	COG0626	cystathionine gamma-synthase activity
AS54_471	COG1473	amidohydrolase
AS54_4715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS54_4717	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS54_4718	COG0454	-acetyltransferase
AS54_4719	COG0517	IMP dehydrogenase activity
AS54_4720	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS54_4723	COG0745	RESPONSE REGULATOR receiver
AS54_4725	COG0666	response to abiotic stimulus
AS54_4732	COG1609	Transcriptional regulator
AS54_4733	COG4851	CamS sex pheromone cAM373 precursor
AS54_4734	COG3118	belongs to the thioredoxin family
AS54_4736	COG2309	aminopeptidase activity
AS54_474	COG0450	alkyl hydroperoxide reductase
AS54_4740	COG0577	efflux transmembrane transporter activity
AS54_4741	COG1136	(ABC) transporter
AS54_4744	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_4745	COG1695	Transcriptional regulator
AS54_4749	COG1674	ftsk spoiiie
AS54_475	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AS54_4751	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS54_4753	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS54_4754	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AS54_4755	COG1363	Peptidase, m42
AS54_4757	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_4760	COG0510	thiamine kinase activity
AS54_4761	COG1523	belongs to the glycosyl hydrolase 13 family
AS54_4763	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS54_4764	COG1349	DNA-binding transcription factor activity
AS54_4765	COG1187	pseudouridine synthase activity
AS54_4766	COG2244	polysaccharide biosynthetic process
AS54_4767	COG2081	HI0933 family
AS54_4768	COG2814	Major facilitator Superfamily
AS54_477	COG0235	Class ii aldolase
AS54_4770	COG3832	glyoxalase III activity
AS54_4774	COG1329	Transcriptional regulator
AS54_4779	COG0314	molybdopterin synthase activity
AS54_478	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_4780	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS54_4781	COG0303	'Molybdopterin
AS54_4783	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS54_4784	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS54_4788	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_479	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_4790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS54_4798	COG2814	Major facilitator Superfamily
AS54_4799	COG0475	glutathione-regulated potassium exporter activity
AS54_48	COG0305	Participates in initiation and elongation during chromosome replication
AS54_480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_4800	COG0490	domain, Protein
AS54_4801	COG0582	viral genome integration into host DNA
AS54_4804	COG1136	(ABC) transporter
AS54_4808	COG1242	4 iron, 4 sulfur cluster binding
AS54_4809	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS54_4812	COG1794	racemase activity, acting on amino acids and derivatives
AS54_4816	COG2267	carboxylic ester hydrolase activity
AS54_4817	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS54_4818	COG0671	phosphoesterase, PA-phosphatase related
AS54_4819	COG0438	transferase activity, transferring glycosyl groups
AS54_4821	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS54_483	COG0166	Belongs to the GPI family
AS54_4833	COG0546	phosphoglycolate phosphatase activity
AS54_4834	COG1349	DNA-binding transcription factor activity
AS54_4836	COG5002	protein histidine kinase activity
AS54_4837	COG4191	Histidine kinase
AS54_4838	COG2267	carboxylic ester hydrolase activity
AS54_4839	COG1368	sulfuric ester hydrolase activity
AS54_4842	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS54_4843	COG1116	anion transmembrane transporter activity
AS54_4844	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS54_4847	COG0546	phosphoglycolate phosphatase activity
AS54_4849	COG0494	nUDIX hydrolase
AS54_4854	COG0288	reversible hydration of carbon dioxide
AS54_4856	COG1271	oxidase subunit
AS54_4857	COG1294	oxidase, subunit
AS54_4861	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_4866	COG1842	Phage shock protein A
AS54_4880	COG3859	Proton-coupled thiamine transporter YuaJ
AS54_4881	COG5002	protein histidine kinase activity
AS54_4882	COG0745	RESPONSE REGULATOR receiver
AS54_4888	COG1597	lipid kinase activity
AS54_4893	COG0586	Pfam SNARE associated Golgi protein
AS54_4897	COG0577	efflux transmembrane transporter activity
AS54_4898	COG1136	(ABC) transporter
AS54_4899	COG3708	Transcriptional regulator
AS54_4899	COG2207	Transcriptional regulator
AS54_4900	COG0745	RESPONSE REGULATOR receiver
AS54_4901	COG2205	protein histidine kinase activity
AS54_4902	COG0577	efflux transmembrane transporter activity
AS54_4903	COG0577	efflux transmembrane transporter activity
AS54_4904	COG1136	(ABC) transporter
AS54_4905	COG0577	efflux transmembrane transporter activity
AS54_4912	COG3964	amidohydrolase
AS54_4916	COG4948	Mandelate Racemase Muconate Lactonizing
AS54_4918	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS54_4919	COG0596	Alpha beta hydrolase
AS54_492	COG3541	Predicted nucleotidyltransferase
AS54_4921	COG1169	isochorismate synthase
AS54_4922	COG1575	Belongs to the MenA family. Type 1 subfamily
AS54_4923	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS54_4924	COG1278	Cold shock
AS54_4928	COG0058	SHG alpha-glucan phosphorylase activity
AS54_493	COG2814	Major facilitator Superfamily
AS54_4930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS54_4934	COG1404	Belongs to the peptidase S8 family
AS54_4935	COG0039	L-malate dehydrogenase activity
AS54_494	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS54_494	COG0723	plastoquinol--plastocyanin reductase activity
AS54_4954	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS54_496	COG0765	amino acid transport
AS54_4962	COG1285	pathogenesis
AS54_4964	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS54_4966	COG2155	Conserved Protein
AS54_4967	COG1098	S1 RNA binding domain
AS54_4968	COG0436	Aminotransferase
AS54_4969	COG1522	sequence-specific DNA binding
AS54_497	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS54_4970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS54_4971	COG2267	carboxylic ester hydrolase activity
AS54_4974	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS54_4978	COG5018	Exonuclease
AS54_4979	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS54_4982	COG0423	glycine-tRNA ligase activity
AS54_4983	COG2050	protein possibly involved in aromatic compounds catabolism
AS54_4985	COG1268	BioY protein
AS54_4986	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS54_4987	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS54_499	COG0840	transmembrane signaling receptor activity
AS54_4990	COG3584	3D domain protein
AS54_4993	COG1252	NADH dehydrogenase
AS54_4999	COG1683	Conserved Protein
AS54_50	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS54_500	COG0366	Alpha amylase catalytic
AS54_5001	COG0316	Belongs to the HesB IscA family
AS54_5004	COG1252	NADH dehydrogenase
AS54_5005	COG2274	protein secretion by the type I secretion system
AS54_5006	COG0390	transport system, permease component
AS54_5007	COG2824	Alkylphosphonate utilization operon protein PhnA
AS54_501	COG2190	(PTS) system
AS54_501	COG1263	PTS System
AS54_501	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_5011	COG4837	Protein of unknown function (DUF1462)
AS54_5012	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS54_5014	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS54_5015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS54_5018	COG1136	(ABC) transporter
AS54_5018	COG0577	efflux transmembrane transporter activity
AS54_5019	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS54_5020	COG0647	UMP catabolic process
AS54_5022	COG2445	Protein of unknown function DUF86
AS54_5023	COG1494	fructose-1,6-bisphosphatase
AS54_5026	COG4470	Protein conserved in bacteria
AS54_5028	COG0789	Transcriptional regulator
AS54_5029	COG4377	Putative membrane peptidase family (DUF2324)
AS54_5034	COG0739	heme binding
AS54_5036	COG3377	Domain of unknown function (DUF1805)
AS54_5037	COG0737	Belongs to the 5'-nucleotidase family
AS54_5038	COG1695	Transcriptional regulator
AS54_5040	COG0719	Fe-S assembly protein
AS54_5041	COG0822	iron-sulfur transferase activity
AS54_5042	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS54_5043	COG0719	Fe-S assembly protein
AS54_5044	COG0396	ATPase activity
AS54_5045	COG1464	Belongs to the NlpA lipoprotein family
AS54_5046	COG1464	Belongs to the NlpA lipoprotein family
AS54_5047	COG2011	ABC-type metal ion transport system permease component
AS54_5050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS54_5051	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS54_5053	COG1393	Belongs to the ArsC family
AS54_5062	COG0039	L-malate dehydrogenase activity
AS54_5069	COG1309	transcriptional regulator
AS54_507	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AS54_5070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_5073	COG4555	ABC transporter
AS54_5078	COG1960	acyl-CoA dehydrogenase activity
AS54_5079	COG0183	Belongs to the thiolase family
AS54_5080	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS54_5080	COG1024	Enoyl-CoA hydratase
AS54_5082	COG1686	Belongs to the peptidase S11 family
AS54_5085	COG0011	TIGRFAM Protein of
AS54_5086	COG0840	transmembrane signaling receptor activity
AS54_5090	COG2814	Major facilitator Superfamily
AS54_5091	COG0531	amino acid
AS54_5094	COG0706	membrane insertase activity
AS54_5096	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS54_51	COG4241	membrane
AS54_510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS54_5104	COG0586	Pfam SNARE associated Golgi protein
AS54_5106	COG1376	ErfK ybiS ycfS ynhG family protein
AS54_5107	COG0745	RESPONSE REGULATOR receiver
AS54_5108	COG5002	protein histidine kinase activity
AS54_5112	COG0840	transmembrane signaling receptor activity
AS54_5113	COG0840	transmembrane signaling receptor activity
AS54_5114	COG2151	metal-sulfur cluster biosynthetic enzyme
AS54_5115	COG3227	Zinc metalloprotease (Elastase)
AS54_5116	COG1741	Belongs to the pirin family
AS54_5119	COG0475	glutathione-regulated potassium exporter activity
AS54_512	COG1116	anion transmembrane transporter activity
AS54_5120	COG0490	domain, Protein
AS54_5121	COG1115	amino acid carrier protein
AS54_5122	COG0783	Belongs to the Dps family
AS54_5125	COG1611	Belongs to the LOG family
AS54_5129	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_5130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_5131	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_5132	COG1115	amino acid carrier protein
AS54_5133	COG1115	amino acid carrier protein
AS54_5134	COG2910	NAD(P)H-binding
AS54_5138	COG0656	L-ascorbic acid biosynthetic process
AS54_5139	COG2814	Major facilitator Superfamily
AS54_514	COG0488	(ABC) transporter
AS54_5140	COG1733	regulation of RNA biosynthetic process
AS54_5142	COG1252	NADH dehydrogenase
AS54_5143	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS54_5144	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS54_5146	COG0840	transmembrane signaling receptor activity
AS54_5146	COG3290	protein histidine kinase activity
AS54_5148	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS54_5153	COG0488	(ABC) transporter
AS54_5154	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS54_5155	COG3223	Belongs to the PsiE family
AS54_5163	COG0557	exoribonuclease II activity
AS54_5164	COG1647	Serine aminopeptidase, S33
AS54_5165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS54_5174	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS54_5177	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS54_5195	COG4974	Belongs to the 'phage' integrase family
AS54_5199	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS54_5202	COG2323	membrane
AS54_5204	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS54_5206	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS54_5208	COG1051	belongs to the nudix hydrolase family
AS54_5210	COG0492	ferredoxin-NADP+ reductase activity
AS54_5211	COG0457	Tetratricopeptide repeat
AS54_5212	COG0110	maltose O-acetyltransferase activity
AS54_5216	COG1950	PFAM Membrane protein of
AS54_5218	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS54_5219	COG0556	nucleotide-excision repair
AS54_5222	COG0789	Transcriptional regulator
AS54_5227	COG2855	membrane
AS54_5228	COG0583	DNA-binding transcription factor activity
AS54_5230	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS54_5231	COG0488	(ABC) transporter
AS54_5233	COG1132	(ABC) transporter
AS54_5234	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS54_5235	COG0793	Belongs to the peptidase S41A family
AS54_5235	COG3409	Peptidoglycan-binding domain 1 protein
AS54_5236	COG2177	Part of the ABC transporter FtsEX involved in
AS54_5237	COG2884	Cell division ATP-binding protein ftsE
AS54_5239	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS54_524	COG2270	Major facilitator Superfamily
AS54_5241	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS54_5242	COG1278	Cold shock
AS54_5243	COG1040	competence protein
AS54_5244	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS54_5245	COG1388	LysM domain
AS54_5245	COG0791	NLP P60 protein
AS54_5246	COG1733	regulation of RNA biosynthetic process
AS54_5247	COG1307	EDD domain protein, DegV family
AS54_5248	COG1739	Uncharacterized protein family UPF0029
AS54_5249	COG1316	TRANSCRIPTIONal
AS54_5250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS54_5251	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS54_5252	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS54_5254	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS54_5254	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AS54_5258	COG1486	melibiose metabolic process
AS54_5259	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS54_5260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS54_5262	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS54_5266	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS54_5268	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS54_5269	COG1301	dicarboxylic acid transport
AS54_5271	COG0346	lactoylglutathione lyase activity
AS54_5275	COG1511	domain protein
AS54_5276	COG0583	DNA-binding transcription factor activity
AS54_5277	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AS54_5279	COG1271	oxidase subunit
AS54_5280	COG1294	oxidase, subunit
AS54_5281	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS54_5283	COG1620	l-lactate permease
AS54_5286	COG2389	metal-binding protein
AS54_5288	COG1368	sulfuric ester hydrolase activity
AS54_5290	COG1388	LysM domain
AS54_5290	COG0791	NLP P60 protein
AS54_5291	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_5293	COG1215	transferase activity, transferring glycosyl groups
AS54_5295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS54_5296	COG3584	3D domain protein
AS54_5296	COG1388	LysM domain
AS54_53	COG0629	single-stranded DNA binding
AS54_530	COG2310	stress, protein
AS54_5301	COG4715	Zinc finger, swim domain protein
AS54_5302	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS54_5308	COG1191	sigma factor activity
AS54_531	COG2310	stress, protein
AS54_5311	COG0577	efflux transmembrane transporter activity
AS54_5312	COG1136	(ABC) transporter
AS54_532	COG2310	stress, protein
AS54_5320	COG0745	RESPONSE REGULATOR receiver
AS54_5321	COG1482	cell wall glycoprotein biosynthetic process
AS54_5322	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS54_5322	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS54_5322	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS54_5323	COG3711	transcriptional antiterminator
AS54_5323	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS54_5324	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS54_5327	COG1482	cell wall glycoprotein biosynthetic process
AS54_5328	COG0662	Cupin 2, conserved barrel domain protein
AS54_5328	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AS54_5329	COG0438	transferase activity, transferring glycosyl groups
AS54_533	COG0861	Integral membrane protein TerC family
AS54_5331	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS54_5334	COG2244	polysaccharide biosynthetic process
AS54_5335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS54_5336	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS54_5337	COG4464	protein tyrosine phosphatase activity
AS54_5338	COG0489	protein tyrosine kinase activity
AS54_5339	COG3944	biosynthesis protein
AS54_5340	COG0489	protein tyrosine kinase activity
AS54_5343	COG1609	Transcriptional regulator
AS54_5344	COG0739	heme binding
AS54_5347	COG3279	Response regulator of the LytR AlgR family
AS54_5348	COG2385	sporulation resulting in formation of a cellular spore
AS54_5349	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS54_535	COG3853	Toxic anion resistance protein (TelA)
AS54_5351	COG4836	Membrane
AS54_5352	COG1007	ATP synthesis coupled electron transport
AS54_5353	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS54_5354	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS54_5356	COG0839	Belongs to the complex I subunit 6 family
AS54_5359	COG0649	NAD binding
AS54_5360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS54_5362	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS54_5363	COG3300	MHYT domain
AS54_5363	COG5001	Diguanylate cyclase
AS54_5373	COG0356	it plays a direct role in the translocation of protons across the membrane
AS54_538	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS54_5381	COG0698	ribose 5-phosphate isomerase
AS54_5383	COG2190	(PTS) system
AS54_5384	COG2259	Doxx family
AS54_5385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS54_5390	COG0009	L-threonylcarbamoyladenylate synthase
AS54_5393	COG2890	protein-(glutamine-N5) methyltransferase activity
AS54_5394	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS54_5397	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS54_5398	COG1494	fructose-1,6-bisphosphatase
AS54_5399	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS54_540	COG1295	ribonuclease BN
AS54_5402	COG4821	SIS domain
AS54_5406	COG1960	acyl-CoA dehydrogenase activity
AS54_5407	COG1960	acyl-CoA dehydrogenase activity
AS54_5408	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS54_5409	COG0183	Belongs to the thiolase family
AS54_541	COG2217	Heavy metal translocating P-type atpase
AS54_5410	COG0247	lactate metabolic process
AS54_5410	COG2181	nitrate reductase activity
AS54_5411	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS54_5413	COG5001	Diguanylate cyclase
AS54_5413	COG3300	MHYT domain
AS54_5417	COG2197	response regulator
AS54_5418	COG4585	Histidine kinase
AS54_5419	COG0842	Transport permease protein
AS54_542	COG0697	spore germination
AS54_5420	COG1131	(ABC) transporter
AS54_5421	COG0024	Methionine aminopeptidase
AS54_5423	COG2234	aminopeptidase activity
AS54_5427	COG1595	DNA-templated transcription, initiation
AS54_5429	COG4506	Protein conserved in bacteria
AS54_5430	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS54_5433	COG0010	Belongs to the arginase family
AS54_5434	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS54_5435	COG2814	Major facilitator Superfamily
AS54_5436	COG0789	Transcriptional regulator
AS54_5437	COG0584	glycerophosphoryl diester phosphodiesterase
AS54_5438	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS54_5440	COG1994	Peptidase M50
AS54_5442	COG1078	dGTPase activity
AS54_5443	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_5444	COG1120	ATPase activity
AS54_5445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_5446	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_5450	COG0095	Lipoate-protein ligase
AS54_5451	COG0280	phosphate acetyltransferase
AS54_5454	COG3773	Cell wall hydrolase
AS54_5456	COG2363	Small membrane protein
AS54_5458	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS54_5459	COG2233	PERMEase
AS54_5460	COG0561	phosphatase activity
AS54_5461	COG2814	Major facilitator Superfamily
AS54_5463	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS54_5464	COG1131	(ABC) transporter
AS54_5465	COG2755	lipolytic protein G-D-S-L family
AS54_5466	COG1609	Transcriptional regulator
AS54_5468	COG0460	homoserine dehydrogenase
AS54_547	COG0586	Pfam SNARE associated Golgi protein
AS54_5471	COG1011	Hydrolase
AS54_5472	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS54_5474	COG2197	response regulator
AS54_5475	COG2203	Gaf domain
AS54_5475	COG4585	Histidine kinase
AS54_5476	COG0351	phosphomethylpyrimidine kinase
AS54_5477	COG3706	GGDEF domain
AS54_5478	COG2879	small protein
AS54_5479	COG1966	Carbon starvation protein
AS54_5480	COG3279	Response regulator of the LytR AlgR family
AS54_5481	COG0477	Major facilitator Superfamily
AS54_5488	COG2356	endonuclease I
AS54_55	COG0012	GTP binding
AS54_550	COG3871	stress protein (general stress protein 26)
AS54_5508	COG2801	Transposase and inactivated derivatives
AS54_551	COG0387	Pfam Sodium calcium exchanger
AS54_5510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS54_5511	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS54_5514	COG0671	phosphoesterase, PA-phosphatase related
AS54_5515	COG4196	transglutaminase domain protein
AS54_5518	COG5386	Cell surface protein
AS54_5522	COG2311	Membrane
AS54_553	COG0535	radical SAM domain protein
AS54_557	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS54_5573	COG1674	ftsk spoiiie
AS54_5574	COG0640	Transcriptional regulator
AS54_5575	COG5658	integral membrane protein
AS54_56	COG4481	Protein conserved in bacteria
AS54_561	COG3829	transcription factor binding
AS54_5627	COG1923	regulation of RNA biosynthetic process
AS54_563	COG0833	amino acid
AS54_5635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS54_5636	COG1074	ATP-dependent DNA helicase activity
AS54_5637	COG4974	Belongs to the 'phage' integrase family
AS54_5639	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS54_564	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS54_5642	COG2801	Transposase and inactivated derivatives
AS54_5645	COG2801	Transposase and inactivated derivatives
AS54_5655	COG4974	Belongs to the 'phage' integrase family
AS54_5657	COG2002	toxin-antitoxin pair type II binding
AS54_57	COG0668	transmembrane transport
AS54_570	COG1263	PTS System
AS54_570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_571	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS54_574	COG0463	Glycosyl transferase, family 2
AS54_576	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS54_576	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS54_579	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AS54_583	COG1228	amidohydrolase
AS54_584	COG1090	epimerase
AS54_59	COG1475	DNA binding
AS54_590	COG1988	membrane-bound metal-dependent
AS54_591	COG1194	a g-specific adenine glycosylase
AS54_597	COG1132	(ABC) transporter
AS54_598	COG4129	membrane
AS54_599	COG0067	glutamate synthase
AS54_599	COG0069	glutamate synthase activity
AS54_599	COG0070	glutamate synthase
AS54_60	COG1192	Involved in chromosome partitioning
AS54_601	COG4555	ABC transporter
AS54_605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS54_606	COG0735	belongs to the Fur family
AS54_630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AS54_631	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS54_633	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS54_635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS54_638	COG2766	serine protein kinase
AS54_641	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS54_643	COG1585	Membrane protein implicated in regulation of membrane protease activity
AS54_644	COG2268	Band 7 protein
AS54_646	COG3290	protein histidine kinase activity
AS54_647	COG4565	transcriptional regulatory protein
AS54_648	COG2851	Citrate transporter
AS54_65	COG1847	R3H domain protein
AS54_652	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS54_653	COG0745	RESPONSE REGULATOR receiver
AS54_654	COG5002	protein histidine kinase activity
AS54_656	COG4990	cell redox homeostasis
AS54_658	COG3290	protein histidine kinase activity
AS54_659	COG4565	transcriptional regulatory protein
AS54_66	COG0706	membrane insertase activity
AS54_660	COG3493	citrate carrier protein
AS54_661	COG0281	malic enzyme
AS54_664	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS54_666	COG5002	protein histidine kinase activity
AS54_667	COG0745	RESPONSE REGULATOR receiver
AS54_669	COG0456	acetyltransferase
AS54_669	COG0454	-acetyltransferase
AS54_670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS54_671	COG3383	formate dehydrogenase (NAD+) activity
AS54_672	COG2427	Protein of unknown function (DUF1641)
AS54_675	COG0531	amino acid
AS54_676	COG0640	Transcriptional regulator
AS54_677	COG2217	Heavy metal translocating P-type atpase
AS54_678	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS54_681	COG3227	Zinc metalloprotease (Elastase)
AS54_685	COG2720	vancomycin resistance protein
AS54_686	COG1316	TRANSCRIPTIONal
AS54_687	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS54_688	COG0346	lactoylglutathione lyase activity
AS54_689	COG1253	flavin adenine dinucleotide binding
AS54_690	COG1027	Aspartate ammonia-lyase
AS54_691	COG1620	l-lactate permease
AS54_696	COG3104	oligopeptide transport
AS54_697	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS54_698	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_699	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS54_7	COG0488	(ABC) transporter
AS54_70	COG0592	DNA-directed DNA polymerase activity
AS54_701	COG2226	methyltransferase
AS54_702	COG0156	8-amino-7-oxononanoate synthase activity
AS54_703	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS54_704	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS54_706	COG4548	von Willebrand factor, type A
AS54_707	COG0714	Associated with various cellular activities
AS54_708	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS54_71	COG2501	S4 domain
AS54_712	COG0531	amino acid
AS54_713	COG2188	Transcriptional regulator
AS54_714	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_714	COG1263	PTS System
AS54_715	COG0366	Alpha amylase catalytic
AS54_718	COG0697	spore germination
AS54_719	COG4585	Histidine kinase
AS54_720	COG2197	response regulator
AS54_721	COG1404	Belongs to the peptidase S8 family
AS54_724	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS54_725	COG1115	amino acid carrier protein
AS54_726	COG1126	abc transporter atp-binding protein
AS54_727	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS54_728	COG0765	amino acid transport
AS54_729	COG0765	amino acid transport
AS54_73	COG0187	DNA topoisomerase II activity
AS54_730	COG0833	amino acid
AS54_735	COG2378	regulation of single-species biofilm formation
AS54_736	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS54_737	COG5002	protein histidine kinase activity
AS54_74	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS54_740	COG0659	secondary active sulfate transmembrane transporter activity
AS54_743	COG0747	negative chemotaxis
AS54_745	COG0601	transmembrane transport
AS54_746	COG4608	Belongs to the ABC transporter superfamily
AS54_748	COG2271	Major facilitator Superfamily
AS54_749	COG1846	Transcriptional regulator
AS54_750	COG0477	Major facilitator Superfamily
AS54_751	COG1609	Transcriptional regulator
AS54_752	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS54_754	COG1129	ABC transporter
AS54_755	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS54_756	COG1879	ABC-type sugar transport system periplasmic component
AS54_757	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS54_760	COG1063	alcohol dehydrogenase
AS54_763	COG3568	Endonuclease Exonuclease Phosphatase
AS54_769	COG0840	transmembrane signaling receptor activity
AS54_770	COG3584	3D domain protein
AS54_770	COG1388	LysM domain
AS54_771	COG1476	TRANSCRIPTIONal
AS54_774	COG3104	oligopeptide transport
AS54_776	COG1114	Component of the transport system for branched-chain amino acids
AS54_779	COG1113	amino acid transport
AS54_780	COG2252	PERMEase
AS54_783	COG2153	protein acetylation
AS54_785	COG0475	glutathione-regulated potassium exporter activity
AS54_785	COG0569	domain protein
AS54_788	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS54_789	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS54_790	COG4990	cell redox homeostasis
AS54_793	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS54_794	COG0697	spore germination
AS54_795	COG0531	amino acid
AS54_797	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS54_798	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS54_799	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS54_799	COG1918	ferrous iron import across plasma membrane
AS54_800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS54_801	COG0573	inorganic phosphate transmembrane transporter activity
AS54_802	COG0581	inorganic phosphate transmembrane transporter activity
AS54_804	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS54_82	COG0517	IMP dehydrogenase activity
AS54_82	COG0516	GMP reductase activity
AS54_829	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AS54_83	COG1686	Belongs to the peptidase S11 family
AS54_833	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS54_834	COG1116	anion transmembrane transporter activity
AS54_835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS54_836	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS54_837	COG0352	thiamine-phosphate diphosphorylase activity
AS54_838	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS54_839	COG2104	thiamine diphosphate biosynthetic process
AS54_841	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS54_842	COG0351	phosphomethylpyrimidine kinase
AS54_849	COG2205	protein histidine kinase activity
AS54_850	COG2814	Major facilitator Superfamily
AS54_851	COG1846	Transcriptional regulator
AS54_856	COG1136	(ABC) transporter
AS54_856	COG0577	efflux transmembrane transporter activity
AS54_858	COG2252	PERMEase
AS54_859	COG1028	Short-chain dehydrogenase reductase Sdr
AS54_862	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS54_863	COG1621	beta-fructofuranosidase activity
AS54_864	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_864	COG1263	PTS System
AS54_865	COG1609	Transcriptional regulator
AS54_867	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS54_868	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS54_875	COG0778	Nitroreductase
AS54_876	COG2719	SpoVR family
AS54_877	COG0446	pyridine nucleotide-disulphide oxidoreductase
AS54_878	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_879	COG1937	Protein conserved in bacteria
AS54_880	COG0425	Belongs to the sulfur carrier protein TusA family
AS54_880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_881	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS54_881	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_882	COG0425	Belongs to the sulfur carrier protein TusA family
AS54_883	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS54_885	COG2210	Belongs to the sulfur carrier protein TusA family
AS54_886	COG0730	response to heat
AS54_888	COG1316	TRANSCRIPTIONal
AS54_889	COG0604	alcohol dehydrogenase
AS54_89	COG1428	Deoxynucleoside kinase
AS54_890	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS54_893	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS54_893	COG3711	transcriptional antiterminator
AS54_894	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS54_895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS54_899	COG1388	LysM domain
AS54_899	COG3584	3D domain protein
AS54_90	COG1428	Deoxynucleoside kinase
AS54_900	COG0577	efflux transmembrane transporter activity
AS54_901	COG1136	(ABC) transporter
AS54_903	COG5522	Integral membrane protein (intg_mem_TP0381)
AS54_906	COG0577	efflux transmembrane transporter activity
AS54_907	COG1114	Component of the transport system for branched-chain amino acids
AS54_908	COG3546	catalase activity
AS54_91	COG1335	isochorismatase
AS54_915	COG0586	Pfam SNARE associated Golgi protein
AS54_92	COG0590	tRNA wobble adenosine to inosine editing
AS54_922	COG0531	amino acid
AS54_923	COG0475	glutathione-regulated potassium exporter activity
AS54_925	COG1737	Transcriptional regulator
AS54_927	COG1263	PTS System
AS54_927	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS54_93	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS54_930	COG2259	Doxx family
AS54_934	COG1522	sequence-specific DNA binding
AS54_936	COG2076	Multidrug Resistance protein
AS54_937	COG2076	Multidrug Resistance protein
AS54_938	COG1309	transcriptional regulator
AS54_939	COG2814	Major facilitator Superfamily
AS54_940	COG4533	DNA binding
AS54_941	COG2211	Major facilitator Superfamily
AS54_943	COG0693	protein deglycase activity
AS54_944	COG0693	protein deglycase activity
AS54_944	COG0753	catalase activity
AS54_946	COG0531	amino acid
AS54_949	COG1012	belongs to the aldehyde dehydrogenase family
AS54_950	COG1132	(ABC) transporter
AS54_951	COG1132	(ABC) transporter
AS54_952	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS54_953	COG0765	amino acid transport
AS54_954	COG1126	abc transporter atp-binding protein
AS54_957	COG0189	ligase activity
AS54_963	COG0028	Belongs to the TPP enzyme family
AS54_964	COG3527	Alpha-acetolactate decarboxylase
AS54_966	COG0561	phosphatase activity
AS54_967	COG3409	Peptidoglycan-binding domain 1 protein
AS54_967	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS54_968	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS54_971	COG0659	secondary active sulfate transmembrane transporter activity
AS54_977	COG2244	polysaccharide biosynthetic process
AS54_979	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS54_980	COG4196	transglutaminase domain protein
AS54_984	COG1024	Enoyl-CoA hydratase
AS54_988	COG1363	Peptidase, m42
AS54_992	COG3938	Belongs to the proline racemase family
AS54_996	COG0601	transmembrane transport
AS54_997	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS54_998	COG0444	Belongs to the ABC transporter superfamily
AS54_999	COG4608	Belongs to the ABC transporter superfamily