locus-tag	class	description
NT98_10	COG2879	small protein
NT98_1004	COG0640	Transcriptional regulator
NT98_1005	COG0697	spore germination
NT98_1007	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NT98_1013	COG1862	Preprotein translocase
NT98_1015	COG2323	membrane
NT98_1016	COG2244	polysaccharide biosynthetic process
NT98_1018	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NT98_1018	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NT98_1019	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NT98_102	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NT98_1020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NT98_1020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NT98_1022	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NT98_1027	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NT98_1029	COG0464	growth
NT98_103	COG2259	Doxx family
NT98_1030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NT98_1031	COG1959	2 iron, 2 sulfur cluster binding
NT98_1032	COG1104	cysteine desulfurase activity
NT98_1035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NT98_1039	COG0628	permease
NT98_104	COG2190	(PTS) system
NT98_1045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NT98_1051	COG0768	penicillin binding
NT98_1056	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NT98_1057	COG0626	cystathionine gamma-synthase activity
NT98_1058	COG1012	belongs to the aldehyde dehydrogenase family
NT98_1058	COG1454	alcohol dehydrogenase
NT98_106	COG0698	ribose 5-phosphate isomerase
NT98_1060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_1068	COG2259	Doxx family
NT98_1069	COG2514	catechol 2,3-dioxygenase activity
NT98_1071	COG3186	Phenylalanine-4-hydroxylase
NT98_1072	COG1404	Belongs to the peptidase S8 family
NT98_1088	COG2267	carboxylic ester hydrolase activity
NT98_1090	COG1785	Belongs to the alkaline phosphatase family
NT98_1092	COG2357	RelA SpoT domain protein
NT98_1093	COG0778	Nitroreductase
NT98_1095	COG1595	DNA-templated transcription, initiation
NT98_1097	COG1191	sigma factor activity
NT98_11	COG3706	GGDEF domain
NT98_1100	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NT98_1101	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NT98_1103	COG1534	Rna-binding protein
NT98_1105	COG1713	HD superfamily hydrolase involved in NAD metabolism
NT98_1106	COG0799	negative regulation of ribosome biogenesis
NT98_1107	COG2226	methyltransferase
NT98_1108	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT98_1109	COG1596	polysaccharide export
NT98_1109	COG1555	photosystem II stabilization
NT98_1110	COG2131	deaminase
NT98_1111	COG2333	competence protein COMEC
NT98_1111	COG0658	competence protein
NT98_1113	COG1466	dna polymerase III delta subunit
NT98_1118	COG1733	regulation of RNA biosynthetic process
NT98_1119	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NT98_112	COG0356	it plays a direct role in the translocation of protons across the membrane
NT98_1125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NT98_1126	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NT98_1128	COG1610	YqeY-like protein
NT98_1131	COG1702	phosphate starvation-inducible protein PhoH
NT98_1132	COG1480	7TM receptor with intracellular HD hydrolase
NT98_1134	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NT98_1135	COG0295	cytidine deaminase activity
NT98_1136	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NT98_1139	COG0517	IMP dehydrogenase activity
NT98_1141	COG0358	DNA primase activity
NT98_1142	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NT98_1144	COG2384	SAM-dependent methyltransferase
NT98_1145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NT98_1151	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_1152	COG1121	(ABC) transporter
NT98_1153	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NT98_1154	COG0735	belongs to the Fur family
NT98_1159	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NT98_1160	COG0477	Major facilitator Superfamily
NT98_1162	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NT98_1163	COG0573	inorganic phosphate transmembrane transporter activity
NT98_1164	COG0581	inorganic phosphate transmembrane transporter activity
NT98_1165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NT98_1166	COG0704	Plays a role in the regulation of phosphate uptake
NT98_1167	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NT98_1169	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NT98_1170	COG4483	Protein conserved in bacteria
NT98_1171	COG1940	carbohydrate kinase activity
NT98_1173	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_1177	COG0626	cystathionine gamma-synthase activity
NT98_1178	COG0626	cystathionine gamma-synthase activity
NT98_1179	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NT98_1179	COG0646	methionine synthase
NT98_1180	COG1410	methionine synthase
NT98_1180	COG0646	methionine synthase
NT98_1191	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NT98_1195	COG1459	type II secretion system
NT98_1197	COG4970	Tfp pilus assembly protein FimT
NT98_12	COG0351	phosphomethylpyrimidine kinase
NT98_1210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NT98_1216	COG1725	Transcriptional regulator
NT98_1217	COG1131	(ABC) transporter
NT98_122	COG3300	MHYT domain
NT98_122	COG5001	Diguanylate cyclase
NT98_1224	COG2076	Multidrug Resistance protein
NT98_1225	COG2076	Multidrug Resistance protein
NT98_1227	COG1609	Transcriptional regulator
NT98_1229	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT98_1230	COG0095	Lipoate-protein ligase
NT98_1239	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NT98_1240	COG3872	metal-dependent enzyme
NT98_1243	COG0006	proline dipeptidase activity
NT98_1248	COG3854	ATPases associated with a variety of cellular activities
NT98_125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NT98_1257	COG0511	ligase activity, forming carbon-carbon bonds
NT98_1258	COG0439	Biotin carboxylase
NT98_1259	COG1302	Protein conserved in bacteria
NT98_1264	COG0142	geranyltranstransferase activity
NT98_1266	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NT98_1268	COG0497	DNA recombination
NT98_1269	COG0750	zinc metalloprotease
NT98_1270	COG0745	RESPONSE REGULATOR receiver
NT98_129	COG0839	Belongs to the complex I subunit 6 family
NT98_13	COG4585	Histidine kinase
NT98_13	COG2203	Gaf domain
NT98_1306	COG4962	Type ii secretion system protein e
NT98_131	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NT98_132	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NT98_133	COG1007	ATP synthesis coupled electron transport
NT98_1333	COG2311	Membrane
NT98_1338	COG4196	transglutaminase domain protein
NT98_1339	COG0671	phosphoesterase, PA-phosphatase related
NT98_134	COG4836	Membrane
NT98_1342	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NT98_1343	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NT98_1345	COG2801	Transposase and inactivated derivatives
NT98_136	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NT98_137	COG2385	sporulation resulting in formation of a cellular spore
NT98_1376	COG2002	toxin-antitoxin pair type II binding
NT98_1378	COG4974	Belongs to the 'phage' integrase family
NT98_138	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_1388	COG2801	Transposase and inactivated derivatives
NT98_1389	COG2801	Transposase and inactivated derivatives
NT98_139	COG3279	Response regulator of the LytR AlgR family
NT98_1390	COG3443	Belongs to the bacterial solute-binding protein 9 family
NT98_1392	COG4974	Belongs to the 'phage' integrase family
NT98_1397	COG0457	Tetratricopeptide repeat
NT98_1399	COG1923	regulation of RNA biosynthetic process
NT98_14	COG2197	response regulator
NT98_1416	COG3344	reverse transcriptase
NT98_142	COG0739	heme binding
NT98_143	COG0726	polysaccharide deacetylase
NT98_143	COG1649	PFAM Uncharacterised BCR, COG1649
NT98_1436	COG3344	reverse transcriptase
NT98_144	COG1609	Transcriptional regulator
NT98_146	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NT98_1469	COG1215	transferase activity, transferring glycosyl groups
NT98_147	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NT98_1470	COG3093	addiction module antidote protein HigA
NT98_1471	COG0584	glycerophosphoryl diester phosphodiesterase
NT98_1473	COG3829	transcription factor binding
NT98_1473	COG3290	protein histidine kinase activity
NT98_1474	COG0280	phosphate acetyltransferase
NT98_1475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NT98_1477	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NT98_1478	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NT98_1479	COG0022	dehydrogenase e1 component
NT98_148	COG0463	Glycosyl transferase, family 2
NT98_148	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NT98_1480	COG0508	dehydrogenase complex catalyzes the overall conversion of
NT98_1481	COG0772	Belongs to the SEDS family
NT98_1482	COG2323	membrane
NT98_1486	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_1487	COG0765	amino acid transport
NT98_1488	COG1126	abc transporter atp-binding protein
NT98_1489	COG4129	membrane
NT98_149	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NT98_1490	COG1376	ErfK ybiS ycfS ynhG family protein
NT98_1492	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_1493	COG2195	Cleaves the N-terminal amino acid of tripeptides
NT98_1495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NT98_1496	COG1285	pathogenesis
NT98_150	COG1682	transport, permease protein
NT98_1500	COG1760	l-serine dehydratase
NT98_1501	COG1760	l-serine dehydratase
NT98_1502	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT98_1503	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_1504	COG0300	oxidoreductase activity
NT98_1509	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NT98_151	COG1134	teichoic acid transport
NT98_1513	COG1522	sequence-specific DNA binding
NT98_1515	COG0737	Belongs to the 5'-nucleotidase family
NT98_1518	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NT98_1521	COG2226	methyltransferase
NT98_1521	COG1073	alpha beta
NT98_1522	COG4106	trans-aconitate 2-methyltransferase activity
NT98_1527	COG0307	riboflavin synthase, alpha
NT98_1528	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NT98_1528	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NT98_153	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NT98_1531	COG1073	alpha beta
NT98_1532	COG0456	acetyltransferase
NT98_1533	COG1609	Transcriptional regulator
NT98_1534	COG2056	Na+-H+ antiporter family
NT98_1535	COG0596	Alpha beta hydrolase
NT98_1537	COG0737	Belongs to the 5'-nucleotidase family
NT98_1537	COG1525	nuclease
NT98_1537	COG4085	toxin activity
NT98_1539	COG0456	acetyltransferase
NT98_1539	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NT98_1540	COG0656	L-ascorbic acid biosynthetic process
NT98_1541	COG0667	Aldo Keto reductase
NT98_1545	COG1300	Membrane
NT98_1546	COG0735	belongs to the Fur family
NT98_1548	COG4974	Belongs to the 'phage' integrase family
NT98_1553	COG0598	Magnesium transport protein CorA
NT98_1556	COG1846	Transcriptional regulator
NT98_156	COG4464	protein tyrosine phosphatase activity
NT98_1560	COG1131	(ABC) transporter
NT98_1561	COG1725	Transcriptional regulator
NT98_1562	COG1686	Belongs to the peptidase S11 family
NT98_1566	COG0733	neurotransmitter:sodium symporter activity
NT98_157	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NT98_1571	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT98_1574	COG0697	spore germination
NT98_1575	COG0561	phosphatase activity
NT98_1576	COG4086	secreted protein
NT98_1577	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NT98_1578	COG0456	acetyltransferase
NT98_1579	COG1547	Domain of unknown function (DUF309)
NT98_158	COG0745	RESPONSE REGULATOR receiver
NT98_1584	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NT98_1588	COG3711	transcriptional antiterminator
NT98_1589	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT98_1589	COG2190	(PTS) system
NT98_1589	COG1263	PTS System
NT98_1594	COG0778	Nitroreductase
NT98_1595	COG2203	Gaf domain
NT98_1595	COG2199	diguanylate cyclase activity
NT98_1597	COG2084	Dehydrogenase
NT98_16	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NT98_1604	COG0436	Aminotransferase
NT98_1605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NT98_1609	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_1610	COG1695	Transcriptional regulator
NT98_1617	COG0183	Belongs to the thiolase family
NT98_1618	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NT98_1625	COG3842	ATPase activity
NT98_1626	COG0366	Alpha amylase catalytic
NT98_1628	COG2182	Extracellular solute-binding protein
NT98_1629	COG1175	transmembrane transport
NT98_1630	COG3833	ABC-type maltose transport systems, permease component
NT98_1631	COG1609	Transcriptional regulator
NT98_1632	COG0436	Aminotransferase
NT98_1634	COG2205	protein histidine kinase activity
NT98_1636	COG3209	COG3209 Rhs family protein
NT98_1644	COG2814	Major facilitator Superfamily
NT98_165	COG1136	(ABC) transporter
NT98_1652	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NT98_1654	COG1408	metallophosphoesterase
NT98_1655	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_1656	COG2200	EAL domain
NT98_1659	COG4703	Protein of unknown function (DUF1797)
NT98_166	COG0577	efflux transmembrane transporter activity
NT98_1661	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NT98_1663	COG0517	IMP dehydrogenase activity
NT98_1664	COG0583	DNA-binding transcription factor activity
NT98_1668	COG0569	domain protein
NT98_1669	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NT98_1671	COG0561	phosphatase activity
NT98_1672	COG0242	peptide deformylase activity
NT98_1674	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NT98_1675	COG0022	dehydrogenase e1 component
NT98_1685	COG1982	Orn Lys Arg decarboxylase major
NT98_1689	COG0483	inositol monophosphate 1-phosphatase activity
NT98_169	COG1191	sigma factor activity
NT98_1694	COG4896	Protein conserved in bacteria
NT98_1696	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NT98_1697	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NT98_1699	COG0772	Belongs to the SEDS family
NT98_17	COG1011	Hydrolase
NT98_1700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NT98_1707	COG3336	cytochrome c oxidase
NT98_1709	COG2340	Cysteine-rich secretory protein family
NT98_1712	COG0406	alpha-ribazole phosphatase activity
NT98_1713	COG3679	Belongs to the UPF0342 family
NT98_1716	COG0742	ribosomal rna small subunit methyltransferase
NT98_1717	COG3314	Sporulation integral membrane protein YlbJ
NT98_1719	COG1752	Esterase of the alpha-beta hydrolase superfamily
NT98_1720	COG3480	Lon protease (S16) C-terminal proteolytic domain
NT98_1722	COG1399	metal-binding, possibly nucleic acid-binding protein
NT98_1726	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NT98_1729	COG4839	cell division protein FtsL
NT98_1731	COG0768	penicillin binding
NT98_1732	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NT98_1735	COG0772	Belongs to the SEDS family
NT98_1736	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NT98_1738	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NT98_1739	COG0849	cell division
NT98_1740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NT98_1742	COG1191	sigma factor activity
NT98_1743	COG1191	sigma factor activity
NT98_1744	COG1873	PFAM PRC-barrel domain
NT98_1746	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NT98_1748	COG0762	integral membrane protein
NT98_1749	COG2302	S4 RNA-binding domain
NT98_175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NT98_1750	COG3599	regulation of cell shape
NT98_1754	COG0564	pseudouridine synthase activity
NT98_176	COG4715	Zinc finger, swim domain protein
NT98_1766	COG3069	C4-dicarboxylate transmembrane transporter activity
NT98_1769	COG0006	proline dipeptidase activity
NT98_1772	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NT98_1773	COG1561	YicC-like family, N-terminal region
NT98_1775	COG0194	GDP metabolic process
NT98_1777	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NT98_1778	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NT98_1779	COG0242	peptide deformylase activity
NT98_1781	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NT98_1781	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NT98_1783	COG0631	protein serine/threonine phosphatase activity
NT98_1784	COG2815	serine threonine protein kinase
NT98_1784	COG0515	serine threonine protein kinase
NT98_1786	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NT98_1787	COG1564	THIamine pyrophosphokinase
NT98_1789	COG1302	Protein conserved in bacteria
NT98_1790	COG1461	Dihydroxyacetone kinase
NT98_1791	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NT98_1794	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NT98_1795	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_1798	COG1196	nuclear chromosome segregation
NT98_1799	COG0552	protein localization to endoplasmic reticulum
NT98_1801	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NT98_1803	COG1837	Belongs to the UPF0109 family
NT98_181	COG1388	LysM domain
NT98_181	COG3584	3D domain protein
NT98_1811	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NT98_1812	COG0758	DNA mediated transformation
NT98_1813	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NT98_1815	COG4974	Belongs to the 'phage' integrase family
NT98_182	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NT98_1821	COG0528	UMP kinase activity
NT98_1824	COG4589	Belongs to the CDS family
NT98_1826	COG0750	zinc metalloprotease
NT98_1830	COG0195	Participates in both transcription termination and antitermination
NT98_1831	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NT98_1832	COG1358	cellular component organization or biogenesis
NT98_1834	COG1550	Protein conserved in bacteria
NT98_1837	COG0196	riboflavin kinase activity
NT98_184	COG1215	transferase activity, transferring glycosyl groups
NT98_1840	COG0726	polysaccharide deacetylase
NT98_1841	COG0612	Peptidase, M16
NT98_1842	COG1873	PFAM PRC-barrel domain
NT98_1843	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NT98_1844	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NT98_1853	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NT98_1854	COG0527	aspartate kinase activity
NT98_1856	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NT98_1857	COG0740	serine-type endopeptidase activity
NT98_1859	COG1674	ftsk spoiiie
NT98_186	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_1860	COG2188	Transcriptional regulator
NT98_1865	COG0612	Peptidase, M16
NT98_1866	COG0612	Peptidase, M16
NT98_1867	COG0300	oxidoreductase activity
NT98_187	COG1388	LysM domain
NT98_187	COG0791	NLP P60 protein
NT98_1870	COG1426	Protein conserved in bacteria
NT98_1871	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NT98_1875	COG1692	metallophosphoesterase
NT98_1876	COG2359	stage V sporulation protein S
NT98_1878	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NT98_1878	COG0674	pyruvate-flavodoxin oxidoreductase activity
NT98_1879	COG1013	pyruvate-flavodoxin oxidoreductase activity
NT98_1881	COG4550	Control of competence regulator ComK, YlbF/YmcA
NT98_189	COG1368	sulfuric ester hydrolase activity
NT98_1891	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NT98_1893	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NT98_1894	COG1368	sulfuric ester hydrolase activity
NT98_1896	COG3773	Cell wall hydrolase
NT98_1897	COG1404	Belongs to the peptidase S8 family
NT98_1899	COG0823	Involved in the tonB-independent uptake of proteins
NT98_1900	COG2723	6-phospho-beta-galactosidase activity
NT98_1901	COG2188	Transcriptional regulator
NT98_1903	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NT98_1905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_1907	COG1346	cytolysis
NT98_1909	COG0384	phenazine biosynthesis protein PhzF
NT98_191	COG2389	metal-binding protein
NT98_1915	COG5001	Diguanylate cyclase
NT98_1915	COG3300	MHYT domain
NT98_1916	COG2267	carboxylic ester hydrolase activity
NT98_1919	COG2364	Membrane
NT98_1921	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NT98_1922	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NT98_1923	COG2169	Transcriptional regulator
NT98_1924	COG0708	Exodeoxyribonuclease III
NT98_1925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_1926	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_1927	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_1928	COG1120	ATPase activity
NT98_1929	COG2819	hydrolase of the alpha beta superfamily
NT98_193	COG1620	l-lactate permease
NT98_1931	COG1937	Protein conserved in bacteria
NT98_1932	COG2608	mercury ion transmembrane transporter activity
NT98_1933	COG2217	Heavy metal translocating P-type atpase
NT98_1936	COG2116	formate transmembrane transporter activity
NT98_1937	COG1408	metallophosphoesterase
NT98_1939	COG1113	amino acid transport
NT98_1942	COG2322	membrane
NT98_1943	COG1979	alcohol dehydrogenase
NT98_1944	COG1349	DNA-binding transcription factor activity
NT98_1945	COG1105	Belongs to the carbohydrate kinase PfkB family
NT98_1946	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NT98_1946	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NT98_1946	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT98_1947	COG3584	3D domain protein
NT98_1947	COG1388	LysM domain
NT98_195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NT98_1952	COG2801	Transposase and inactivated derivatives
NT98_1955	COG0464	growth
NT98_1957	COG2860	membrane
NT98_1958	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NT98_1959	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NT98_196	COG1294	oxidase, subunit
NT98_1960	COG0789	Transcriptional regulator
NT98_1961	COG0174	glutamine synthetase
NT98_1967	COG1695	Transcriptional regulator
NT98_197	COG1271	oxidase subunit
NT98_1971	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NT98_1973	COG0737	Belongs to the 5'-nucleotidase family
NT98_1974	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_1976	COG3639	organic phosphonate transmembrane transporter activity
NT98_1981	COG1132	(ABC) transporter
NT98_1982	COG1132	(ABC) transporter
NT98_1985	COG3409	Peptidoglycan-binding domain 1 protein
NT98_1985	COG5632	N-Acetylmuramoyl-L-alanine amidase
NT98_1987	COG0730	response to heat
NT98_1990	COG1346	cytolysis
NT98_1992	COG0583	DNA-binding transcription factor activity
NT98_1994	COG1131	(ABC) transporter
NT98_1998	COG0785	Cytochrome C biogenesis protein
NT98_1999	COG4846	Membrane protein involved in cytochrome C biogenesis
NT98_2	COG0840	transmembrane signaling receptor activity
NT98_200	COG0583	DNA-binding transcription factor activity
NT98_2006	COG2226	methyltransferase
NT98_201	COG1511	domain protein
NT98_2011	COG0010	Belongs to the arginase family
NT98_2012	COG1329	Transcriptional regulator
NT98_2013	COG1902	pentaerythritol trinitrate reductase activity
NT98_2014	COG0069	glutamate synthase activity
NT98_2016	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NT98_2017	COG0346	lactoylglutathione lyase activity
NT98_2018	COG0400	carboxylic ester hydrolase activity
NT98_2019	COG5002	protein histidine kinase activity
NT98_202	COG0346	lactoylglutathione lyase activity
NT98_2021	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_2029	COG1396	sequence-specific DNA binding
NT98_2032	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_2033	COG1268	BioY protein
NT98_2034	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_2035	COG0183	Belongs to the thiolase family
NT98_2038	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NT98_204	COG1301	dicarboxylic acid transport
NT98_2040	COG2211	Major facilitator Superfamily
NT98_2044	COG0726	polysaccharide deacetylase
NT98_2046	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NT98_2047	COG2274	protein secretion by the type I secretion system
NT98_2049	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT98_205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NT98_2055	COG0824	Thioesterase
NT98_2056	COG4841	protein insertion into membrane
NT98_2060	COG0745	RESPONSE REGULATOR receiver
NT98_2061	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT98_2062	COG1832	CoA-binding protein
NT98_2063	COG0187	DNA topoisomerase II activity
NT98_2064	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NT98_2065	COG0673	inositol 2-dehydrogenase activity
NT98_2069	COG1131	(ABC) transporter
NT98_207	COG1447	Phosphotransferase system cellobiose-specific component IIA
NT98_2071	COG0346	lactoylglutathione lyase activity
NT98_2072	COG1595	DNA-templated transcription, initiation
NT98_2074	COG1316	TRANSCRIPTIONal
NT98_2075	COG4166	transmembrane transport
NT98_2077	COG4166	transmembrane transport
NT98_2078	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NT98_2080	COG2226	methyltransferase
NT98_2087	COG0531	amino acid
NT98_2090	COG0697	spore germination
NT98_2091	COG3383	formate dehydrogenase (NAD+) activity
NT98_2092	COG2427	Protein of unknown function (DUF1641)
NT98_2093	COG5609	conserved protein (DUF2294)
NT98_2094	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NT98_2096	COG2116	formate transmembrane transporter activity
NT98_2097	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT98_2098	COG0303	'Molybdopterin
NT98_2099	COG0314	molybdopterin synthase activity
NT98_21	COG0460	homoserine dehydrogenase
NT98_2101	COG0489	protein tyrosine kinase activity
NT98_2104	COG3326	Membrane
NT98_2105	COG2962	Rard protein
NT98_2106	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NT98_2107	COG1657	PFAM Prenyltransferase squalene oxidase
NT98_2109	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_211	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NT98_2110	COG1012	belongs to the aldehyde dehydrogenase family
NT98_2112	COG4145	pantothenate transmembrane transporter activity
NT98_2115	COG0165	Argininosuccinate lyase
NT98_2117	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_212	COG1447	Phosphotransferase system cellobiose-specific component IIA
NT98_2120	COG0494	nUDIX hydrolase
NT98_2122	COG0716	FMN binding
NT98_2124	COG1278	Cold shock
NT98_2129	COG2720	vancomycin resistance protein
NT98_213	COG1486	melibiose metabolic process
NT98_2130	COG0765	amino acid transport
NT98_2131	COG1126	abc transporter atp-binding protein
NT98_2132	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_2133	COG2514	catechol 2,3-dioxygenase activity
NT98_2135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT98_2136	COG2514	catechol 2,3-dioxygenase activity
NT98_2139	COG1285	pathogenesis
NT98_2142	COG3852	Histidine kinase
NT98_2148	COG1309	transcriptional regulator
NT98_2151	COG0825	malonyl-CoA metabolic process
NT98_2155	COG0277	FAD linked oxidase domain protein
NT98_2156	COG0385	Bile acid
NT98_2159	COG2808	Putative FMN-binding domain
NT98_2160	COG0457	Tetratricopeptide repeat
NT98_2163	COG0604	alcohol dehydrogenase
NT98_2164	COG0640	Transcriptional regulator
NT98_2165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NT98_2167	COG0584	glycerophosphoryl diester phosphodiesterase
NT98_217	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NT98_217	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NT98_2173	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NT98_2180	COG1164	Oligoendopeptidase f
NT98_2181	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NT98_2184	COG1193	negative regulation of DNA recombination
NT98_2188	COG0583	DNA-binding transcription factor activity
NT98_219	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NT98_2195	COG3739	integral membrane protein
NT98_2196	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_2197	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_2198	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NT98_2201	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NT98_2202	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NT98_2206	COG2814	Major facilitator Superfamily
NT98_2207	COG1113	amino acid transport
NT98_2209	COG1695	Transcriptional regulator
NT98_221	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NT98_2219	COG2072	flavoprotein involved in K transport
NT98_222	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NT98_2228	COG1151	hydroxylamine reductase activity
NT98_223	COG1316	TRANSCRIPTIONal
NT98_2233	COG3152	Membrane
NT98_2237	COG1280	lysine exporter protein (LysE YggA)
NT98_2239	COG1191	sigma factor activity
NT98_224	COG1739	Uncharacterized protein family UPF0029
NT98_2241	COG0726	polysaccharide deacetylase
NT98_2246	COG1733	regulation of RNA biosynthetic process
NT98_2247	COG2249	NAD(P)H dehydrogenase (quinone) activity
NT98_2248	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_225	COG1307	EDD domain protein, DegV family
NT98_2251	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_2253	COG0384	phenazine biosynthesis protein PhzF
NT98_2257	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_226	COG1733	regulation of RNA biosynthetic process
NT98_2260	COG0673	inositol 2-dehydrogenase activity
NT98_2261	COG2188	Transcriptional regulator
NT98_2262	COG1393	Belongs to the ArsC family
NT98_2266	COG0814	amino acid
NT98_227	COG0791	NLP P60 protein
NT98_227	COG1388	LysM domain
NT98_2273	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NT98_2275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NT98_2276	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NT98_2278	COG1070	Carbohydrate kinase
NT98_2279	COG2706	6-phosphogluconolactonase activity
NT98_228	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NT98_2280	COG3813	Protein conserved in bacteria
NT98_2281	COG1357	PFAM Pentapeptide repeats (8 copies)
NT98_2282	COG0697	spore germination
NT98_2287	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NT98_2289	COG0789	Transcriptional regulator
NT98_229	COG1040	competence protein
NT98_2290	COG1253	flavin adenine dinucleotide binding
NT98_2296	COG0477	Major facilitator Superfamily
NT98_2298	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NT98_23	COG1609	Transcriptional regulator
NT98_230	COG1278	Cold shock
NT98_2304	COG0628	permease
NT98_2306	COG0180	Tryptophanyl-tRNA synthetase
NT98_2308	COG1136	(ABC) transporter
NT98_2308	COG0577	efflux transmembrane transporter activity
NT98_231	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NT98_2310	COG0110	maltose O-acetyltransferase activity
NT98_2311	COG1940	carbohydrate kinase activity
NT98_2312	COG0346	lactoylglutathione lyase activity
NT98_2319	COG1011	Hydrolase
NT98_2324	COG1131	(ABC) transporter
NT98_2326	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_233	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NT98_2332	COG0778	Nitroreductase
NT98_2333	COG1733	regulation of RNA biosynthetic process
NT98_2337	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NT98_2343	COG0789	Transcriptional regulator
NT98_2345	COG1309	transcriptional regulator
NT98_2346	COG2814	Major facilitator Superfamily
NT98_2347	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NT98_2349	COG2356	endonuclease I
NT98_235	COG2884	Cell division ATP-binding protein ftsE
NT98_2350	COG1288	antiporter activity
NT98_2351	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NT98_2354	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NT98_236	COG2177	Part of the ABC transporter FtsEX involved in
NT98_2361	COG2249	NAD(P)H dehydrogenase (quinone) activity
NT98_2363	COG2031	fatty acid transporter
NT98_2365	COG1309	transcriptional regulator
NT98_2366	COG2076	Multidrug Resistance protein
NT98_237	COG0793	Belongs to the peptidase S41A family
NT98_237	COG3409	Peptidoglycan-binding domain 1 protein
NT98_2370	COG1131	(ABC) transporter
NT98_2371	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NT98_2374	COG2814	Major facilitator Superfamily
NT98_2375	COG1846	Transcriptional regulator
NT98_2378	COG0477	Major facilitator Superfamily
NT98_238	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT98_2380	COG2843	Capsule synthesis protein
NT98_2381	COG1876	peptidase activity
NT98_2388	COG3409	Peptidoglycan-binding domain 1 protein
NT98_2388	COG5632	N-Acetylmuramoyl-L-alanine amidase
NT98_239	COG1132	(ABC) transporter
NT98_2398	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NT98_24	COG2755	lipolytic protein G-D-S-L family
NT98_2402	COG1619	proteins homologs of microcin C7 resistance protein MccF
NT98_2405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_2407	COG5002	protein histidine kinase activity
NT98_2407	COG3850	Histidine kinase
NT98_241	COG0655	NAD(P)H dehydrogenase (quinone) activity
NT98_2410	COG0577	efflux transmembrane transporter activity
NT98_2414	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NT98_2418	COG1476	TRANSCRIPTIONal
NT98_2423	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NT98_2429	COG3850	Histidine kinase
NT98_2429	COG5002	protein histidine kinase activity
NT98_243	COG0583	DNA-binding transcription factor activity
NT98_2431	COG0745	RESPONSE REGULATOR receiver
NT98_2437	COG2814	Major facilitator Superfamily
NT98_2439	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_2440	COG2226	methyltransferase
NT98_2445	COG0346	lactoylglutathione lyase activity
NT98_2449	COG1522	sequence-specific DNA binding
NT98_2450	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_2451	COG1309	transcriptional regulator
NT98_2452	COG2814	Major facilitator Superfamily
NT98_2461	COG0640	Transcriptional regulator
NT98_2462	COG0346	lactoylglutathione lyase activity
NT98_2463	COG0798	PFAM Bile acid sodium symporter
NT98_2466	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_2471	COG4585	Histidine kinase
NT98_2472	COG0577	efflux transmembrane transporter activity
NT98_2473	COG1136	(ABC) transporter
NT98_2474	COG4641	Protein conserved in bacteria
NT98_2475	COG1575	Belongs to the MenA family. Type 1 subfamily
NT98_2479	COG0583	DNA-binding transcription factor activity
NT98_2480	COG2814	Major facilitator Superfamily
NT98_2482	COG2814	Major facilitator Superfamily
NT98_2483	COG5609	conserved protein (DUF2294)
NT98_2484	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NT98_2486	COG0288	reversible hydration of carbon dioxide
NT98_2487	COG0657	acetylesterase activity
NT98_2489	COG2814	Major facilitator Superfamily
NT98_2491	COG0415	Belongs to the DNA photolyase family
NT98_25	COG1131	(ABC) transporter
NT98_250	COG0789	Transcriptional regulator
NT98_2502	COG0598	Magnesium transport protein CorA
NT98_2503	COG0583	DNA-binding transcription factor activity
NT98_2507	COG1335	isochorismatase
NT98_2508	COG2267	carboxylic ester hydrolase activity
NT98_2509	COG0737	Belongs to the 5'-nucleotidase family
NT98_2514	COG1115	amino acid carrier protein
NT98_2516	COG2066	Belongs to the glutaminase family
NT98_2517	COG4191	Histidine kinase
NT98_2518	COG0784	Response regulator, receiver
NT98_2519	COG0697	spore germination
NT98_2520	COG0531	amino acid
NT98_2522	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT98_2523	COG0531	amino acid
NT98_2524	COG0322	excinuclease ABC activity
NT98_2525	COG2207	Transcriptional regulator
NT98_253	COG0556	nucleotide-excision repair
NT98_2530	COG5002	protein histidine kinase activity
NT98_2534	COG1396	sequence-specific DNA binding
NT98_2535	COG0252	asparaginase activity
NT98_2536	COG1027	Aspartate ammonia-lyase
NT98_2538	COG1063	alcohol dehydrogenase
NT98_254	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NT98_2542	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_2544	COG3848	Pyruvate phosphate dikinase
NT98_2544	COG0574	Belongs to the PEP-utilizing enzyme family
NT98_2547	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NT98_2555	COG1960	acyl-CoA dehydrogenase activity
NT98_2557	COG0640	Transcriptional regulator
NT98_2558	COG0860	N-Acetylmuramoyl-L-alanine amidase
NT98_2559	COG3142	Participates in the control of copper homeostasis
NT98_256	COG1950	PFAM Membrane protein of
NT98_2561	COG1414	Transcriptional regulator
NT98_2562	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NT98_2563	COG1984	allophanate hydrolase subunit 2
NT98_2569	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NT98_2577	COG4978	Transcriptional regulator
NT98_2577	COG0789	Transcriptional regulator
NT98_2578	COG4335	DNA alkylation repair
NT98_2580	COG0833	amino acid
NT98_2582	COG0730	response to heat
NT98_2590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_2594	COG0456	acetyltransferase
NT98_26	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NT98_260	COG0110	maltose O-acetyltransferase activity
NT98_2600	COG1725	Transcriptional regulator
NT98_2607	COG1846	Transcriptional regulator
NT98_2608	COG0778	Nitroreductase
NT98_261	COG0457	Tetratricopeptide repeat
NT98_2612	COG0659	secondary active sulfate transmembrane transporter activity
NT98_2613	COG2824	Alkylphosphonate utilization operon protein PhnA
NT98_2615	COG0714	Associated with various cellular activities
NT98_262	COG0492	ferredoxin-NADP+ reductase activity
NT98_2620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NT98_2622	COG0753	catalase activity
NT98_2623	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NT98_2627	COG0714	Associated with various cellular activities
NT98_2631	COG0346	lactoylglutathione lyase activity
NT98_2632	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_2638	COG4377	Putative membrane peptidase family (DUF2324)
NT98_264	COG1051	belongs to the nudix hydrolase family
NT98_2641	COG3655	Transcriptional regulator
NT98_2643	COG1785	Belongs to the alkaline phosphatase family
NT98_2645	COG3239	Fatty acid desaturase
NT98_2646	COG1690	Belongs to the RtcB family
NT98_2647	COG0833	amino acid
NT98_2648	COG1414	Transcriptional regulator
NT98_2649	COG4187	Peptidase family M20/M25/M40
NT98_2650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT98_2653	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_2657	COG2329	Antibiotic biosynthesis monooxygenase
NT98_266	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NT98_2664	COG1070	Carbohydrate kinase
NT98_2665	COG2390	Transcriptional regulator
NT98_2668	COG1172	Belongs to the binding-protein-dependent transport system permease family
NT98_2672	COG3584	3D domain protein
NT98_2672	COG1388	LysM domain
NT98_268	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT98_2680	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NT98_2680	COG1605	Chorismate mutase
NT98_2683	COG0287	Prephenate dehydrogenase
NT98_2686	COG1309	transcriptional regulator
NT98_2687	COG1033	growth of symbiont in host cell
NT98_2687	COG2409	Drug exporters of the RND superfamily
NT98_2696	COG0488	(ABC) transporter
NT98_2697	COG1368	sulfuric ester hydrolase activity
NT98_2698	COG0861	Integral membrane protein TerC family
NT98_2699	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT98_270	COG2323	membrane
NT98_2701	COG3037	sugar-specific permease SgaT UlaA
NT98_2703	COG0726	polysaccharide deacetylase
NT98_2704	COG0346	lactoylglutathione lyase activity
NT98_2709	COG0454	-acetyltransferase
NT98_2710	COG2318	DinB family
NT98_2711	COG0697	spore germination
NT98_2715	COG2746	aminoglycoside 3-N-acetyltransferase activity
NT98_2719	COG2816	NAD+ diphosphatase activity
NT98_2722	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NT98_2723	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NT98_2724	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NT98_2726	COG0628	permease
NT98_273	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT98_2737	COG1131	(ABC) transporter
NT98_2740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NT98_2742	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NT98_2743	COG0436	Aminotransferase
NT98_2750	COG2226	methyltransferase
NT98_2753	COG2261	transglycosylase associated protein
NT98_2758	COG0477	Major facilitator Superfamily
NT98_2758	COG2814	Major facilitator Superfamily
NT98_2759	COG4533	DNA binding
NT98_2760	COG0789	Transcriptional regulator
NT98_2761	COG1664	Polymer-forming cytoskeletal
NT98_2763	COG2814	Major facilitator Superfamily
NT98_2774	COG1307	EDD domain protein, DegV family
NT98_2775	COG1522	sequence-specific DNA binding
NT98_2777	COG0531	amino acid
NT98_2778	COG1164	Oligoendopeptidase f
NT98_278	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NT98_2787	COG0745	RESPONSE REGULATOR receiver
NT98_2788	COG3850	Histidine kinase
NT98_2788	COG5002	protein histidine kinase activity
NT98_2789	COG2936	dipeptidyl-peptidase activity
NT98_2799	COG4948	Mandelate Racemase Muconate Lactonizing
NT98_28	COG2814	Major facilitator Superfamily
NT98_2801	COG4166	transmembrane transport
NT98_2804	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NT98_2807	COG0586	Pfam SNARE associated Golgi protein
NT98_281	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NT98_2815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NT98_2816	COG3938	Belongs to the proline racemase family
NT98_2819	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NT98_2820	COG1012	belongs to the aldehyde dehydrogenase family
NT98_2821	COG1115	amino acid carrier protein
NT98_2822	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NT98_2825	COG3397	chitin binding
NT98_2830	COG4637	Psort location Cytoplasmic, score
NT98_2835	COG0514	ATP-dependent DNA helicase (RecQ)
NT98_2839	COG3973	AAA domain
NT98_2848	COG2333	competence protein COMEC
NT98_2848	COG0658	competence protein
NT98_2850	COG2315	Protein conserved in bacteria
NT98_2851	COG2226	methyltransferase
NT98_2852	COG2205	protein histidine kinase activity
NT98_2855	COG1819	glycosyl
NT98_2856	COG3397	chitin binding
NT98_2857	COG2153	protein acetylation
NT98_2863	COG0517	IMP dehydrogenase activity
NT98_2863	COG4175	Glycine betaine
NT98_2864	COG4176	ABC-type proline glycine betaine transport system permease component
NT98_2870	COG0572	uridine kinase
NT98_2871	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NT98_2871	COG0456	acetyltransferase
NT98_2872	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_2874	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NT98_2875	COG0022	dehydrogenase e1 component
NT98_2876	COG0508	dehydrogenase complex catalyzes the overall conversion of
NT98_2877	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NT98_288	COG1346	cytolysis
NT98_2880	COG1349	DNA-binding transcription factor activity
NT98_2883	COG3284	Transcriptional regulator
NT98_2887	COG1309	transcriptional regulator
NT98_289	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NT98_2895	COG3409	Peptidoglycan-binding domain 1 protein
NT98_2895	COG3773	Cell wall hydrolase
NT98_2896	COG2959	enzyme of heme biosynthesis
NT98_2899	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_29	COG0561	phosphatase activity
NT98_290	COG1647	Serine aminopeptidase, S33
NT98_291	COG0557	exoribonuclease II activity
NT98_2910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_2911	COG0697	spore germination
NT98_2913	COG0201	protein transport
NT98_2916	COG3227	Zinc metalloprotease (Elastase)
NT98_2917	COG1523	belongs to the glycosyl hydrolase 13 family
NT98_2918	COG1523	belongs to the glycosyl hydrolase 13 family
NT98_2919	COG1523	belongs to the glycosyl hydrolase 13 family
NT98_2929	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NT98_2938	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_2939	COG0697	spore germination
NT98_2940	COG0697	spore germination
NT98_2944	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NT98_2949	COG2223	nitrite transmembrane transporter activity
NT98_2952	COG2816	NAD+ diphosphatase activity
NT98_2953	COG0592	DNA-directed DNA polymerase activity
NT98_2954	COG0592	DNA-directed DNA polymerase activity
NT98_2955	COG1051	belongs to the nudix hydrolase family
NT98_2960	COG3878	Protein conserved in bacteria
NT98_2964	COG4667	esterase of the alpha-beta hydrolase superfamily
NT98_2973	COG0322	excinuclease ABC activity
NT98_2993	COG0584	glycerophosphoryl diester phosphodiesterase
NT98_2994	COG0584	glycerophosphoryl diester phosphodiesterase
NT98_30	COG2233	PERMEase
NT98_3002	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NT98_3003	COG2814	Major facilitator Superfamily
NT98_3006	COG0693	protein deglycase activity
NT98_3014	COG0671	phosphoesterase, PA-phosphatase related
NT98_3015	COG0604	alcohol dehydrogenase
NT98_3016	COG5002	protein histidine kinase activity
NT98_3019	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NT98_3022	COG2205	protein histidine kinase activity
NT98_3027	COG1794	racemase activity, acting on amino acids and derivatives
NT98_3028	COG1819	glycosyl
NT98_3029	COG5002	protein histidine kinase activity
NT98_303	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_3030	COG0561	phosphatase activity
NT98_3038	COG2124	cytochrome p450
NT98_304	COG0488	(ABC) transporter
NT98_3048	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NT98_3051	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_3052	COG1725	Transcriptional regulator
NT98_3053	COG0460	homoserine dehydrogenase
NT98_3057	COG0577	efflux transmembrane transporter activity
NT98_3058	COG0577	efflux transmembrane transporter activity
NT98_3059	COG1136	(ABC) transporter
NT98_3064	COG2205	protein histidine kinase activity
NT98_3066	COG0745	RESPONSE REGULATOR receiver
NT98_3069	COG3773	Cell wall hydrolase
NT98_3070	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NT98_3072	COG3386	PFAM SMP-30 Gluconolaconase
NT98_3074	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NT98_3076	COG2323	membrane
NT98_3080	COG2368	4-hydroxyphenylacetate
NT98_3081	COG2368	4-hydroxyphenylacetate
NT98_3083	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_3087	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NT98_309	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NT98_3091	COG2226	methyltransferase
NT98_3093	COG2814	Major facilitator Superfamily
NT98_3097	COG3227	Zinc metalloprotease (Elastase)
NT98_31	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NT98_3101	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NT98_3106	COG1686	Belongs to the peptidase S11 family
NT98_3107	COG2318	DinB family
NT98_311	COG3290	protein histidine kinase activity
NT98_311	COG0840	transmembrane signaling receptor activity
NT98_3110	COG0572	uridine kinase
NT98_3114	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NT98_3115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NT98_3116	COG1024	Enoyl-CoA hydratase
NT98_3117	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NT98_3118	COG0511	ligase activity, forming carbon-carbon bonds
NT98_3119	COG0439	Biotin carboxylase
NT98_3120	COG1960	acyl-CoA dehydrogenase activity
NT98_3123	COG1309	transcriptional regulator
NT98_3125	COG1131	(ABC) transporter
NT98_3127	COG1408	metallophosphoesterase
NT98_3128	COG2367	Beta-lactamase
NT98_313	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NT98_3132	COG1595	DNA-templated transcription, initiation
NT98_3133	COG0768	penicillin binding
NT98_3134	COG0768	penicillin binding
NT98_3136	COG0726	polysaccharide deacetylase
NT98_3138	COG0076	glutamate decarboxylase activity
NT98_3139	COG1533	DNA photolyase activity
NT98_314	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NT98_3143	COG0814	amino acid
NT98_3144	COG1760	l-serine dehydratase
NT98_3145	COG1760	l-serine dehydratase
NT98_3149	COG0110	maltose O-acetyltransferase activity
NT98_315	COG1252	NADH dehydrogenase
NT98_3152	COG2195	Cleaves the N-terminal amino acid of tripeptides
NT98_3156	COG1846	Transcriptional regulator
NT98_3157	COG3961	Belongs to the TPP enzyme family
NT98_3158	COG3961	Belongs to the TPP enzyme family
NT98_3159	COG2226	methyltransferase
NT98_3161	COG0500	methyltransferase
NT98_3161	COG3615	Tellurite resistance protein tehB
NT98_3162	COG0577	efflux transmembrane transporter activity
NT98_3162	COG1136	(ABC) transporter
NT98_3165	COG1309	transcriptional regulator
NT98_3175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_318	COG1733	regulation of RNA biosynthetic process
NT98_3180	COG1846	Transcriptional regulator
NT98_3184	COG2971	BadF BadG BcrA BcrD
NT98_3189	COG1649	PFAM Uncharacterised BCR, COG1649
NT98_319	COG2814	Major facilitator Superfamily
NT98_3194	COG1595	DNA-templated transcription, initiation
NT98_3196	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NT98_320	COG0656	L-ascorbic acid biosynthetic process
NT98_3201	COG1396	sequence-specific DNA binding
NT98_3205	COG1132	(ABC) transporter
NT98_3206	COG1132	(ABC) transporter
NT98_3210	COG2258	MOSC domain
NT98_3211	COG0583	DNA-binding transcription factor activity
NT98_3214	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NT98_3215	COG0583	DNA-binding transcription factor activity
NT98_3217	COG0561	phosphatase activity
NT98_3218	COG0010	Belongs to the arginase family
NT98_3221	COG1278	Cold shock
NT98_3223	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_3226	COG0596	Alpha beta hydrolase
NT98_323	COG2910	NAD(P)H-binding
NT98_3231	COG1247	-acetyltransferase
NT98_3238	COG1846	Transcriptional regulator
NT98_324	COG1115	amino acid carrier protein
NT98_3246	COG2226	methyltransferase
NT98_3248	COG0028	Belongs to the TPP enzyme family
NT98_3249	COG0028	Belongs to the TPP enzyme family
NT98_325	COG1115	amino acid carrier protein
NT98_3252	COG2814	Major facilitator Superfamily
NT98_3254	COG1136	(ABC) transporter
NT98_3256	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NT98_3257	COG1187	pseudouridine synthase activity
NT98_3258	COG2329	Antibiotic biosynthesis monooxygenase
NT98_326	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_3261	COG1115	amino acid carrier protein
NT98_3263	COG2318	DinB family
NT98_3265	COG0776	regulation of translation
NT98_3268	COG2814	Major facilitator Superfamily
NT98_327	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_3270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NT98_3271	COG1535	isochorismatase
NT98_3271	COG3433	isochorismatase activity
NT98_3272	COG1021	2,3-dihydroxybenzoate-AMP ligase
NT98_3273	COG1169	isochorismate synthase
NT98_3274	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_3275	COG2223	nitrite transmembrane transporter activity
NT98_3280	COG0420	3'-5' exonuclease activity
NT98_3283	COG1024	Enoyl-CoA hydratase
NT98_3284	COG1280	lysine exporter protein (LysE YggA)
NT98_3286	COG2084	Dehydrogenase
NT98_3287	COG1960	acyl-CoA dehydrogenase activity
NT98_3288	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NT98_3289	COG2079	MmgE PrpD family protein
NT98_3290	COG0372	Belongs to the citrate synthase family
NT98_3291	COG4841	protein insertion into membrane
NT98_3292	COG2814	Major facilitator Superfamily
NT98_3294	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT98_3294	COG4499	WXG100 protein secretion system (Wss), protein YukC
NT98_3298	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_33	COG2363	Small membrane protein
NT98_3304	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NT98_331	COG1611	Belongs to the LOG family
NT98_3311	COG1595	DNA-templated transcription, initiation
NT98_3321	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT98_3322	COG0671	phosphoesterase, PA-phosphatase related
NT98_3323	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NT98_3324	COG4326	sporulation control protein
NT98_3325	COG4991	sh3 domain protein
NT98_3325	COG3064	Membrane
NT98_3325	COG0515	serine threonine protein kinase
NT98_3332	COG1509	lysine 2,3-aminomutase activity
NT98_3333	COG3829	transcription factor binding
NT98_3334	COG0456	acetyltransferase
NT98_3335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NT98_3336	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NT98_3337	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NT98_3338	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NT98_334	COG0783	Belongs to the Dps family
NT98_3341	COG5506	Protein of unknown function (DUF1694)
NT98_3342	COG1012	belongs to the aldehyde dehydrogenase family
NT98_3343	COG1253	flavin adenine dinucleotide binding
NT98_335	COG1115	amino acid carrier protein
NT98_3350	COG1174	glycine betaine transport
NT98_3351	COG0517	IMP dehydrogenase activity
NT98_3351	COG1125	glycine betaine transport
NT98_3358	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NT98_336	COG0490	domain, Protein
NT98_3366	COG1064	alcohol dehydrogenase
NT98_3367	COG1737	Transcriptional regulator
NT98_3368	COG2197	response regulator
NT98_3369	COG4585	Histidine kinase
NT98_3369	COG2203	Gaf domain
NT98_337	COG0475	glutathione-regulated potassium exporter activity
NT98_3370	COG0668	transmembrane transport
NT98_3371	COG1335	isochorismatase
NT98_3374	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT98_3375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_3379	COG0367	asparagine synthase
NT98_338	COG0586	Pfam SNARE associated Golgi protein
NT98_3380	COG0071	Belongs to the small heat shock protein (HSP20) family
NT98_3381	COG1999	signal sequence binding
NT98_3382	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NT98_3383	COG1307	EDD domain protein, DegV family
NT98_3385	COG0805	protein transport
NT98_3387	COG1272	protein, Hemolysin III
NT98_3388	COG0204	Acyl-transferase
NT98_3390	COG0768	penicillin binding
NT98_3393	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NT98_3396	COG0546	phosphoglycolate phosphatase activity
NT98_3398	COG4473	ABC transporter
NT98_3399	COG1131	(ABC) transporter
NT98_3401	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NT98_3402	COG0456	acetyltransferase
NT98_3404	COG1794	racemase activity, acting on amino acids and derivatives
NT98_3405	COG1454	alcohol dehydrogenase
NT98_3406	COG2610	gluconate transmembrane transporter activity
NT98_341	COG1741	Belongs to the pirin family
NT98_3412	COG0733	neurotransmitter:sodium symporter activity
NT98_3414	COG1929	Belongs to the glycerate kinase type-1 family
NT98_3415	COG0017	Asparaginyl-tRNA synthetase
NT98_342	COG3227	Zinc metalloprotease (Elastase)
NT98_3422	COG0018	arginyl-trna synthetase
NT98_3423	COG2136	Putative SAM-dependent methyltransferase
NT98_3423	COG2521	methyltransferase
NT98_3427	COG1413	lyase activity
NT98_3428	COG0629	single-stranded DNA binding
NT98_343	COG2151	metal-sulfur cluster biosynthetic enzyme
NT98_3431	COG0488	(ABC) transporter
NT98_3432	COG1418	mRNA catabolic process
NT98_3434	COG2359	stage V sporulation protein S
NT98_344	COG0840	transmembrane signaling receptor activity
NT98_3440	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NT98_3441	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NT98_3442	COG2146	nitrite reductase [NAD(P)H] activity
NT98_3443	COG1587	Uroporphyrinogen-III synthase
NT98_3443	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NT98_3445	COG1648	precorrin-2 dehydrogenase activity
NT98_3449	COG2223	nitrite transmembrane transporter activity
NT98_3451	COG0314	molybdopterin synthase activity
NT98_3452	COG0303	'Molybdopterin
NT98_3453	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT98_3454	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NT98_3455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NT98_3457	COG1131	(ABC) transporter
NT98_3460	COG2181	nitrate reductase activity
NT98_3461	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NT98_3462	COG1140	nitrate reductase beta subunit
NT98_3463	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NT98_3464	COG0714	Associated with various cellular activities
NT98_3465	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NT98_3466	COG1305	Transglutaminase-like
NT98_3467	COG0386	Belongs to the glutathione peroxidase family
NT98_3471	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NT98_3474	COG1595	DNA-templated transcription, initiation
NT98_3475	COG0604	alcohol dehydrogenase
NT98_3477	COG0346	lactoylglutathione lyase activity
NT98_3481	COG2226	methyltransferase
NT98_3486	COG3874	Sporulation protein YtfJ
NT98_349	COG5002	protein histidine kinase activity
NT98_3493	COG0456	acetyltransferase
NT98_3499	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_35	COG3773	Cell wall hydrolase
NT98_350	COG0745	RESPONSE REGULATOR receiver
NT98_3500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_3501	COG1819	glycosyl
NT98_3506	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NT98_3508	COG0561	phosphatase activity
NT98_351	COG1376	ErfK ybiS ycfS ynhG family protein
NT98_3515	COG2211	Major facilitator Superfamily
NT98_3518	COG1876	peptidase activity
NT98_3520	COG0860	N-Acetylmuramoyl-L-alanine amidase
NT98_3523	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NT98_3524	COG1114	Component of the transport system for branched-chain amino acids
NT98_3527	COG1253	flavin adenine dinucleotide binding
NT98_3528	COG2839	Protein conserved in bacteria
NT98_3529	COG0702	epimerase
NT98_353	COG0586	Pfam SNARE associated Golgi protein
NT98_3532	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT98_3533	COG1607	acyl-coa hydrolase
NT98_3534	COG3689	TIGRFAM TIGR03943 family protein
NT98_3535	COG0701	Predicted permease
NT98_3537	COG2244	polysaccharide biosynthetic process
NT98_3538	COG0586	Pfam SNARE associated Golgi protein
NT98_3539	COG1051	belongs to the nudix hydrolase family
NT98_3540	COG5337	Spore coat protein CotH
NT98_3542	COG0406	alpha-ribazole phosphatase activity
NT98_3545	COG4166	transmembrane transport
NT98_3547	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NT98_3549	COG0702	epimerase
NT98_3551	COG0803	Belongs to the bacterial solute-binding protein 9 family
NT98_3551	COG3443	Belongs to the bacterial solute-binding protein 9 family
NT98_3552	COG0456	acetyltransferase
NT98_3553	COG0523	cobalamin synthesis protein
NT98_3554	COG4989	oxidoreductase activity
NT98_3555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_3556	COG1231	oxidoreductase activity
NT98_3558	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NT98_3561	COG0783	Belongs to the Dps family
NT98_3562	COG3949	Membrane
NT98_3570	COG2814	Major facilitator Superfamily
NT98_3571	COG0667	Aldo Keto reductase
NT98_3572	COG0640	Transcriptional regulator
NT98_3573	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NT98_3574	COG1404	Belongs to the peptidase S8 family
NT98_3575	COG2002	toxin-antitoxin pair type II binding
NT98_3576	COG0577	efflux transmembrane transporter activity
NT98_3583	COG1752	Esterase of the alpha-beta hydrolase superfamily
NT98_3585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_3586	COG1279	arginine transmembrane transporter activity
NT98_3587	COG2814	Major facilitator Superfamily
NT98_3589	COG1082	Xylose isomerase domain protein TIM barrel
NT98_3592	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_3593	COG4264	IucA IucC family
NT98_3595	COG1247	-acetyltransferase
NT98_3596	COG1285	pathogenesis
NT98_3598	COG0726	polysaccharide deacetylase
NT98_3599	COG5002	protein histidine kinase activity
NT98_3600	COG0745	RESPONSE REGULATOR receiver
NT98_3602	COG1316	TRANSCRIPTIONal
NT98_3607	COG0460	homoserine dehydrogenase
NT98_361	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_3611	COG0726	polysaccharide deacetylase
NT98_3614	COG0300	oxidoreductase activity
NT98_3619	COG0745	RESPONSE REGULATOR receiver
NT98_3620	COG2205	protein histidine kinase activity
NT98_3621	COG5002	protein histidine kinase activity
NT98_3622	COG0745	RESPONSE REGULATOR receiver
NT98_3623	COG1132	(ABC) transporter
NT98_3625	COG0791	NLP P60 protein
NT98_3625	COG1388	LysM domain
NT98_3628	COG1686	Belongs to the peptidase S11 family
NT98_3634	COG1216	Glycosyl transferase, family 2
NT98_3636	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NT98_3637	COG4988	ABC transporter
NT98_3638	COG1294	oxidase, subunit
NT98_3639	COG1271	oxidase subunit
NT98_3643	COG1942	4-Oxalocrotonate Tautomerase
NT98_3645	COG0583	DNA-binding transcription factor activity
NT98_3649	COG0411	ABC transporter
NT98_3652	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT98_3653	COG2030	dehydratase
NT98_3654	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_3656	COG0523	cobalamin synthesis protein
NT98_3657	COG1231	oxidoreductase activity
NT98_3659	COG0628	permease
NT98_366	COG0531	amino acid
NT98_3663	COG0778	Nitroreductase
NT98_3664	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NT98_3665	COG1959	2 iron, 2 sulfur cluster binding
NT98_3666	COG0583	DNA-binding transcription factor activity
NT98_3667	COG0697	spore germination
NT98_3668	COG4549	nuclear export factor GLE1
NT98_3669	COG1276	copper resistance
NT98_3669	COG2372	response to copper ion
NT98_367	COG2814	Major facilitator Superfamily
NT98_3671	COG1114	Component of the transport system for branched-chain amino acids
NT98_3675	COG0675	Transposase, IS605 OrfB family
NT98_3676	COG0367	asparagine synthase
NT98_3677	COG0583	DNA-binding transcription factor activity
NT98_3685	COG1522	sequence-specific DNA binding
NT98_3686	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_3690	COG2132	Multicopper oxidase
NT98_3691	COG0006	proline dipeptidase activity
NT98_3696	COG4846	Membrane protein involved in cytochrome C biogenesis
NT98_3699	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NT98_3700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_3702	COG2390	Transcriptional regulator
NT98_3703	COG1309	transcriptional regulator
NT98_3710	COG0531	amino acid
NT98_3712	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NT98_3715	COG1914	H( )-stimulated, divalent metal cation uptake system
NT98_3719	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_372	COG0840	transmembrane signaling receptor activity
NT98_3720	COG4166	transmembrane transport
NT98_3724	COG0427	acetyl-CoA hydrolase
NT98_3725	COG3279	Response regulator of the LytR AlgR family
NT98_3728	COG3384	dioxygenase
NT98_3729	COG2814	Major facilitator Superfamily
NT98_373	COG0011	TIGRFAM Protein of
NT98_3734	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NT98_3738	COG0028	Belongs to the TPP enzyme family
NT98_3739	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT98_3740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NT98_3744	COG2323	membrane
NT98_3745	COG5566	PFAM Mor transcription activator
NT98_3747	COG0733	neurotransmitter:sodium symporter activity
NT98_3748	COG2244	polysaccharide biosynthetic process
NT98_3751	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NT98_3752	COG2223	nitrite transmembrane transporter activity
NT98_3753	COG4166	transmembrane transport
NT98_3754	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NT98_3756	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT98_3758	COG0477	Major facilitator Superfamily
NT98_376	COG1686	Belongs to the peptidase S11 family
NT98_3762	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_3765	COG1051	belongs to the nudix hydrolase family
NT98_3771	COG3620	sequence-specific DNA binding
NT98_3774	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NT98_3775	COG0784	Response regulator, receiver
NT98_3776	COG4191	Histidine kinase
NT98_3777	COG0281	malic enzyme
NT98_3778	COG1027	Aspartate ammonia-lyase
NT98_378	COG1250	3-hydroxyacyl-CoA dehydrogenase
NT98_378	COG1024	Enoyl-CoA hydratase
NT98_3780	COG0528	UMP kinase activity
NT98_3781	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT98_3786	COG1131	(ABC) transporter
NT98_379	COG0183	Belongs to the thiolase family
NT98_3793	COG2733	membrane
NT98_3799	COG0785	Cytochrome C biogenesis protein
NT98_38	COG0280	phosphate acetyltransferase
NT98_380	COG1960	acyl-CoA dehydrogenase activity
NT98_3803	COG3340	Belongs to the peptidase S51 family
NT98_3804	COG0534	Mate efflux family protein
NT98_3808	COG0114	fumarate hydratase activity
NT98_381	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_3810	COG0114	fumarate hydratase activity
NT98_3811	COG4221	oxidoreductase activity
NT98_3812	COG0789	Transcriptional regulator
NT98_3813	COG1757	Na H antiporter
NT98_3814	COG0438	transferase activity, transferring glycosyl groups
NT98_3814	COG1216	Glycosyl transferase, family 2
NT98_3816	COG0701	Predicted permease
NT98_3817	COG0523	cobalamin synthesis protein
NT98_3818	COG0697	spore germination
NT98_3819	COG1802	Transcriptional regulator
NT98_382	COG1309	transcriptional regulator
NT98_3825	COG0367	asparagine synthase
NT98_3827	COG1846	Transcriptional regulator
NT98_3832	COG0406	alpha-ribazole phosphatase activity
NT98_3834	COG1686	Belongs to the peptidase S11 family
NT98_3840	COG1177	transmembrane transport
NT98_3841	COG0725	ABC transporter, periplasmic molybdate-binding protein
NT98_3842	COG3842	ATPase activity
NT98_3849	COG3764	Sortase (surface protein transpeptidase)
NT98_3850	COG3764	Sortase (surface protein transpeptidase)
NT98_3855	COG2329	Antibiotic biosynthesis monooxygenase
NT98_3863	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NT98_3864	COG4786	Flagellar basal body rod
NT98_3865	COG1419	protein localization to endoplasmic reticulum
NT98_3866	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NT98_3867	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NT98_3869	COG1987	bacterial-type flagellum assembly
NT98_3870	COG1338	Plays a role in the flagellum-specific transport system
NT98_3872	COG1776	CheC inhibitor of MCP methylation
NT98_3872	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NT98_3873	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NT98_3875	COG0741	lytic transglycosylase activity
NT98_3876	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NT98_3877	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NT98_3878	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NT98_3879	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NT98_3880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NT98_3882	COG0835	chemotaxis
NT98_3882	COG0784	Response regulator, receiver
NT98_3885	COG1749	Flagellar hook protein flgE
NT98_3889	COG1157	protein secretion by the type III secretion system
NT98_3891	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NT98_3892	COG1766	The M ring may be actively involved in energy transduction
NT98_3893	COG1677	Flagellar hook-basal body complex protein FliE
NT98_3894	COG1558	bacterial-type flagellum-dependent cell motility
NT98_3895	COG1815	bacterial-type flagellum-dependent cell motility
NT98_3898	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NT98_3900	COG1256	bacterial-type flagellum assembly
NT98_3904	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NT98_3907	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NT98_3907	COG1776	CheC inhibitor of MCP methylation
NT98_3908	COG0643	Histidine kinase
NT98_3908	COG2198	Histidine kinase
NT98_3909	COG2201	protein-glutamate methylesterase activity
NT98_391	COG1393	Belongs to the ArsC family
NT98_3911	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NT98_3913	COG1923	regulation of RNA biosynthetic process
NT98_3917	COG2814	Major facilitator Superfamily
NT98_3924	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NT98_3925	COG2323	membrane
NT98_3927	COG4978	Transcriptional regulator
NT98_3927	COG0789	Transcriptional regulator
NT98_3928	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NT98_3929	COG0475	glutathione-regulated potassium exporter activity
NT98_393	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NT98_3931	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NT98_3932	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NT98_3933	COG3162	membrane
NT98_3936	COG1280	lysine exporter protein (LysE YggA)
NT98_3937	COG3403	YqcI/YcgG family
NT98_394	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT98_3944	COG0328	RNA-DNA hybrid ribonuclease activity
NT98_3948	COG0454	-acetyltransferase
NT98_3951	COG0438	transferase activity, transferring glycosyl groups
NT98_3952	COG1215	transferase activity, transferring glycosyl groups
NT98_3955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NT98_396	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NT98_3960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NT98_3963	COG0754	glutathionylspermidine amidase activity
NT98_3968	COG0456	acetyltransferase
NT98_397	COG2011	ABC-type metal ion transport system permease component
NT98_3970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NT98_3972	COG2311	Membrane
NT98_3973	COG2233	PERMEase
NT98_3975	COG0024	Methionine aminopeptidase
NT98_3977	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NT98_3978	COG1199	ATP-dependent helicase activity
NT98_398	COG1464	Belongs to the NlpA lipoprotein family
NT98_3980	COG0116	Belongs to the methyltransferase superfamily
NT98_399	COG1464	Belongs to the NlpA lipoprotein family
NT98_3991	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT98_3991	COG4499	WXG100 protein secretion system (Wss), protein YukC
NT98_3993	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NT98_3994	COG3935	DnaD domain protein
NT98_3998	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NT98_3998	COG1199	ATP-dependent helicase activity
NT98_400	COG0396	ATPase activity
NT98_4005	COG0438	transferase activity, transferring glycosyl groups
NT98_4006	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NT98_4009	COG1694	Mazg nucleotide pyrophosphohydrolase
NT98_401	COG0719	Fe-S assembly protein
NT98_4010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_4012	COG2738	Putative neutral zinc metallopeptidase
NT98_4015	COG4347	Protein of unknown function (DUF1405)
NT98_4016	COG2010	Cytochrome c
NT98_4016	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NT98_4017	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NT98_402	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NT98_4021	COG0457	Tetratricopeptide repeat
NT98_4026	COG0142	geranyltranstransferase activity
NT98_4028	COG0142	geranyltranstransferase activity
NT98_403	COG0822	iron-sulfur transferase activity
NT98_4031	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NT98_404	COG0719	Fe-S assembly protein
NT98_4045	COG0252	asparaginase activity
NT98_4046	COG0492	ferredoxin-NADP+ reductase activity
NT98_4050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NT98_4051	COG4862	establishment of competence for transformation
NT98_4053	COG1408	metallophosphoesterase
NT98_4055	COG1266	CAAX protease self-immunity
NT98_4056	COG0514	ATP-dependent DNA helicase (RecQ)
NT98_4058	COG1141	Ferredoxin
NT98_4059	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NT98_406	COG1695	Transcriptional regulator
NT98_4061	COG4942	peptidase
NT98_4062	COG2096	Adenosyltransferase
NT98_4063	COG5002	protein histidine kinase activity
NT98_4064	COG0745	RESPONSE REGULATOR receiver
NT98_4065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NT98_4066	COG1333	cytochrome c biogenesis protein
NT98_4068	COG1187	pseudouridine synthase activity
NT98_4069	COG0700	Nucleoside recognition
NT98_4070	COG2715	membrane protein required for spore maturation
NT98_4071	COG1686	Belongs to the peptidase S11 family
NT98_4072	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NT98_4075	COG0392	lysyltransferase activity
NT98_4075	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NT98_4079	COG5002	protein histidine kinase activity
NT98_408	COG0737	Belongs to the 5'-nucleotidase family
NT98_4080	COG0582	viral genome integration into host DNA
NT98_4082	COG1801	Protein of unknown function DUF72
NT98_4083	COG3852	Histidine kinase
NT98_4086	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT98_4087	COG1392	Phosphate transport regulator
NT98_4088	COG0306	phosphate transporter
NT98_4089	COG0730	response to heat
NT98_409	COG3377	Domain of unknown function (DUF1805)
NT98_4099	COG1114	Component of the transport system for branched-chain amino acids
NT98_4101	COG2197	response regulator
NT98_4102	COG4585	Histidine kinase
NT98_4103	COG4758	membrane
NT98_4106	COG1757	Na H antiporter
NT98_411	COG0739	heme binding
NT98_4110	COG0733	neurotransmitter:sodium symporter activity
NT98_4111	COG1648	precorrin-2 dehydrogenase activity
NT98_4115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NT98_4116	COG0529	Catalyzes the synthesis of activated sulfate
NT98_4121	COG0019	diaminopimelate decarboxylase activity
NT98_4123	COG1368	sulfuric ester hydrolase activity
NT98_4124	COG1183	phosphatidylcholine synthase activity
NT98_4125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NT98_4127	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NT98_4142	COG0440	acetolactate synthase activity
NT98_4143	COG0028	Belongs to the TPP enzyme family
NT98_4144	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT98_4148	COG3874	Sporulation protein YtfJ
NT98_4149	COG4709	membrane
NT98_4150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NT98_4152	COG1301	dicarboxylic acid transport
NT98_4153	COG1846	Transcriptional regulator
NT98_4157	COG0534	Mate efflux family protein
NT98_416	COG4377	Putative membrane peptidase family (DUF2324)
NT98_4164	COG0716	FMN binding
NT98_4169	COG1696	Membrane protein involved in D-alanine export
NT98_417	COG0789	Transcriptional regulator
NT98_4171	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NT98_4172	COG2070	2-Nitropropane dioxygenase
NT98_4173	COG1619	proteins homologs of microcin C7 resistance protein MccF
NT98_4175	COG1335	isochorismatase
NT98_4177	COG1522	sequence-specific DNA binding
NT98_4179	COG1266	CAAX protease self-immunity
NT98_4180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NT98_4181	COG1131	(ABC) transporter
NT98_4183	COG1131	(ABC) transporter
NT98_4184	COG1725	Transcriptional regulator
NT98_4185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT98_4186	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT98_4187	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NT98_4188	COG1780	Probably involved in ribonucleotide reductase function
NT98_419	COG4470	Protein conserved in bacteria
NT98_4194	COG4873	Protein conserved in bacteria
NT98_4197	COG0720	synthase
NT98_4199	COG5002	protein histidine kinase activity
NT98_42	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_4201	COG2318	DinB family
NT98_4203	COG1846	Transcriptional regulator
NT98_4204	COG3852	Histidine kinase
NT98_4206	COG2861	carbohydrate metabolic process
NT98_4208	COG0235	Class ii aldolase
NT98_4211	COG1349	DNA-binding transcription factor activity
NT98_4214	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NT98_4216	COG3842	ATPase activity
NT98_4217	COG1840	ABC-type Fe3 transport system, periplasmic component
NT98_422	COG1494	fructose-1,6-bisphosphatase
NT98_4220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NT98_4222	COG3243	poly(R)-hydroxyalkanoic acid synthase
NT98_4223	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_4227	COG2030	dehydratase
NT98_4229	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NT98_423	COG2445	Protein of unknown function DUF86
NT98_4230	COG0861	Integral membrane protein TerC family
NT98_4231	COG2116	formate transmembrane transporter activity
NT98_4233	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NT98_4237	COG2186	Transcriptional regulator
NT98_4238	COG5002	protein histidine kinase activity
NT98_4239	COG0745	RESPONSE REGULATOR receiver
NT98_4241	COG3835	regulator
NT98_4242	COG0277	FAD linked oxidase domain protein
NT98_4243	COG0247	lactate metabolic process
NT98_4244	COG2340	Cysteine-rich secretory protein family
NT98_4246	COG0564	pseudouridine synthase activity
NT98_4248	COG2409	Drug exporters of the RND superfamily
NT98_425	COG0647	UMP catabolic process
NT98_4250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NT98_4252	COG1177	transmembrane transport
NT98_4253	COG1176	ABC-type spermidine putrescine transport system, permease component I
NT98_4255	COG1012	belongs to the aldehyde dehydrogenase family
NT98_4263	COG0681	Belongs to the peptidase S26 family
NT98_4264	COG1686	Belongs to the peptidase S11 family
NT98_4268	COG4974	Belongs to the 'phage' integrase family
NT98_427	COG2249	NAD(P)H dehydrogenase (quinone) activity
NT98_4288	COG1476	TRANSCRIPTIONal
NT98_429	COG1358	cellular component organization or biogenesis
NT98_4290	COG0508	dehydrogenase complex catalyzes the overall conversion of
NT98_4299	COG4640	response to antibiotic
NT98_43	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_4302	COG5634	Uncharacterized conserved protein (DUF2278)
NT98_4303	COG1620	l-lactate permease
NT98_4310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NT98_4310	COG0512	Glutamine amidotransferase of anthranilate synthase
NT98_4312	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NT98_4313	COG5492	domain, Protein
NT98_4317	COG2382	esterase
NT98_4319	COG2153	protein acetylation
NT98_4327	COG1091	dTDP-4-dehydrorhamnose reductase activity
NT98_433	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NT98_4330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NT98_4334	COG0463	Glycosyl transferase, family 2
NT98_4334	COG0457	Tetratricopeptide repeat
NT98_4338	COG1216	Glycosyl transferase, family 2
NT98_4339	COG0772	Belongs to the SEDS family
NT98_434	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NT98_4342	COG0564	pseudouridine synthase activity
NT98_4344	COG2357	RelA SpoT domain protein
NT98_4346	COG4116	CYTH
NT98_4347	COG2346	COG2346, Truncated hemoglobins
NT98_4350	COG1164	Oligoendopeptidase f
NT98_4352	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT98_4353	COG4862	establishment of competence for transformation
NT98_4354	COG0861	Integral membrane protein TerC family
NT98_4355	COG1393	Belongs to the ArsC family
NT98_4357	COG4166	transmembrane transport
NT98_4358	COG0534	Mate efflux family protein
NT98_4359	COG4608	Belongs to the ABC transporter superfamily
NT98_436	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NT98_4360	COG0444	Belongs to the ABC transporter superfamily
NT98_4361	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NT98_4362	COG0601	transmembrane transport
NT98_4363	COG4166	transmembrane transport
NT98_4365	COG0180	Tryptophanyl-tRNA synthetase
NT98_4367	COG5504	Zn-dependent protease
NT98_4368	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NT98_4369	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NT98_437	COG4837	Protein of unknown function (DUF1462)
NT98_4372	COG2267	carboxylic ester hydrolase activity
NT98_4377	COG0561	phosphatase activity
NT98_4380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_4382	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NT98_4385	COG3209	COG3209 Rhs family protein
NT98_4388	COG3209	COG3209 Rhs family protein
NT98_4389	COG2996	Protein conserved in bacteria
NT98_4394	COG0004	ammonium transporteR
NT98_4395	COG0753	catalase activity
NT98_4397	COG0367	asparagine synthase
NT98_44	COG1120	ATPase activity
NT98_4402	COG0179	Fumarylacetoacetate (FAA) hydrolase
NT98_441	COG2824	Alkylphosphonate utilization operon protein PhnA
NT98_4414	COG0398	Pfam SNARE associated Golgi protein
NT98_4416	COG4903	ComK protein
NT98_4419	COG1278	Cold shock
NT98_442	COG0390	transport system, permease component
NT98_4421	COG2224	Isocitrate lyase
NT98_4422	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NT98_4423	COG0497	DNA recombination
NT98_4426	COG0697	spore germination
NT98_4427	COG0501	Belongs to the peptidase M48B family
NT98_4432	COG0745	RESPONSE REGULATOR receiver
NT98_4433	COG2205	protein histidine kinase activity
NT98_4436	COG3708	Transcriptional regulator
NT98_4436	COG2207	Transcriptional regulator
NT98_4437	COG1595	DNA-templated transcription, initiation
NT98_4439	COG1078	dGTPase activity
NT98_444	COG1252	NADH dehydrogenase
NT98_4440	COG1408	metallophosphoesterase
NT98_4441	COG1073	alpha beta
NT98_4445	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_4447	COG0095	Lipoate-protein ligase
NT98_4448	COG1234	tRNA 3'-trailer cleavage
NT98_4450	COG1609	Transcriptional regulator
NT98_4451	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_4454	COG1511	domain protein
NT98_4455	COG1309	transcriptional regulator
NT98_4463	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT98_4464	COG2329	Antibiotic biosynthesis monooxygenase
NT98_4465	COG3428	Bacterial PH domain
NT98_4466	COG3402	PFAM membrane-flanked domain
NT98_4469	COG3428	Bacterial PH domain
NT98_447	COG0316	Belongs to the HesB IscA family
NT98_4470	COG3402	PFAM membrane-flanked domain
NT98_4472	COG1309	transcriptional regulator
NT98_4475	COG4473	ABC transporter
NT98_4476	COG1131	(ABC) transporter
NT98_4477	COG0537	adenosine 5'-monophosphoramidase activity
NT98_4478	COG4980	gas vesicle protein
NT98_4482	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NT98_4483	COG3973	AAA domain
NT98_4484	COG3973	AAA domain
NT98_4488	COG1595	DNA-templated transcription, initiation
NT98_4490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NT98_4492	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NT98_4493	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NT98_4496	COG2267	carboxylic ester hydrolase activity
NT98_4498	COG0346	lactoylglutathione lyase activity
NT98_4499	COG0346	lactoylglutathione lyase activity
NT98_45	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_4500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NT98_4502	COG4717	serine-type aminopeptidase activity
NT98_4503	COG0420	3'-5' exonuclease activity
NT98_451	COG1683	Conserved Protein
NT98_4513	COG0393	Putative heavy-metal-binding
NT98_4518	COG5002	protein histidine kinase activity
NT98_4518	COG0784	Response regulator, receiver
NT98_4518	COG2205	protein histidine kinase activity
NT98_4519	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NT98_4520	COG2208	phosphoserine phosphatase activity
NT98_4522	COG1191	sigma factor activity
NT98_4526	COG2261	transglycosylase associated protein
NT98_4531	COG0596	Alpha beta hydrolase
NT98_454	COG3708	Transcriptional regulator
NT98_4540	COG3437	response regulator, receiver
NT98_4540	COG2770	Histidine kinase
NT98_4543	COG0457	Tetratricopeptide repeat
NT98_4545	COG2376	Dihydroxyacetone kinase
NT98_4547	COG2376	Dihydroxyacetone kinase
NT98_4551	COG1183	phosphatidylcholine synthase activity
NT98_456	COG1252	NADH dehydrogenase
NT98_4562	COG0477	Major facilitator Superfamily
NT98_4565	COG1288	antiporter activity
NT98_4566	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NT98_4571	COG0305	Participates in initiation and elongation during chromosome replication
NT98_4574	COG0305	Participates in initiation and elongation during chromosome replication
NT98_459	COG3584	3D domain protein
NT98_4592	COG3181	Tripartite tricarboxylate transporter family receptor
NT98_4593	COG4565	transcriptional regulatory protein
NT98_4594	COG3290	protein histidine kinase activity
NT98_4595	COG0477	Major facilitator Superfamily
NT98_46	COG1078	dGTPase activity
NT98_4600	COG3409	Peptidoglycan-binding domain 1 protein
NT98_4601	COG1396	sequence-specific DNA binding
NT98_4605	COG5632	N-Acetylmuramoyl-L-alanine amidase
NT98_4609	COG3409	Peptidoglycan-binding domain 1 protein
NT98_4616	COG0305	Participates in initiation and elongation during chromosome replication
NT98_462	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NT98_4627	COG1363	Peptidase, m42
NT98_463	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NT98_4631	COG1024	Enoyl-CoA hydratase
NT98_4635	COG4196	transglutaminase domain protein
NT98_4636	COG0860	N-Acetylmuramoyl-L-alanine amidase
NT98_4638	COG2244	polysaccharide biosynthetic process
NT98_4639	COG0653	protein targeting
NT98_4644	COG0659	secondary active sulfate transmembrane transporter activity
NT98_4646	COG4978	Transcriptional regulator
NT98_4646	COG0789	Transcriptional regulator
NT98_4648	COG0586	Pfam SNARE associated Golgi protein
NT98_465	COG1268	BioY protein
NT98_4651	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NT98_4652	COG5632	N-Acetylmuramoyl-L-alanine amidase
NT98_4652	COG3409	Peptidoglycan-binding domain 1 protein
NT98_4654	COG0561	phosphatase activity
NT98_4657	COG3527	Alpha-acetolactate decarboxylase
NT98_4658	COG0028	Belongs to the TPP enzyme family
NT98_4660	COG0784	Response regulator, receiver
NT98_4660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NT98_4662	COG4585	Histidine kinase
NT98_4666	COG0189	ligase activity
NT98_4669	COG1126	abc transporter atp-binding protein
NT98_467	COG2050	protein possibly involved in aromatic compounds catabolism
NT98_4670	COG0765	amino acid transport
NT98_4671	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_4672	COG1132	(ABC) transporter
NT98_4673	COG1132	(ABC) transporter
NT98_4674	COG1012	belongs to the aldehyde dehydrogenase family
NT98_4676	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NT98_4677	COG0531	amino acid
NT98_4679	COG0693	protein deglycase activity
NT98_468	COG0423	glycine-tRNA ligase activity
NT98_4684	COG1733	regulation of RNA biosynthetic process
NT98_4686	COG0577	efflux transmembrane transporter activity
NT98_4687	COG1136	(ABC) transporter
NT98_4688	COG0577	efflux transmembrane transporter activity
NT98_4689	COG1136	(ABC) transporter
NT98_4694	COG2814	Major facilitator Superfamily
NT98_4695	COG1309	transcriptional regulator
NT98_4696	COG2076	Multidrug Resistance protein
NT98_4697	COG2076	Multidrug Resistance protein
NT98_4701	COG1522	sequence-specific DNA binding
NT98_4705	COG2259	Doxx family
NT98_4707	COG1263	PTS System
NT98_4707	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT98_4709	COG1737	Transcriptional regulator
NT98_471	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NT98_4711	COG0475	glutathione-regulated potassium exporter activity
NT98_4712	COG0531	amino acid
NT98_4719	COG0586	Pfam SNARE associated Golgi protein
NT98_472	COG5018	Exonuclease
NT98_4726	COG3546	catalase activity
NT98_4727	COG1114	Component of the transport system for branched-chain amino acids
NT98_4731	COG5522	Integral membrane protein (intg_mem_TP0381)
NT98_4733	COG1136	(ABC) transporter
NT98_4734	COG0577	efflux transmembrane transporter activity
NT98_4735	COG1388	LysM domain
NT98_4735	COG3584	3D domain protein
NT98_4739	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NT98_4740	COG1447	Phosphotransferase system cellobiose-specific component IIA
NT98_4741	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NT98_4741	COG3711	transcriptional antiterminator
NT98_4743	COG2814	Major facilitator Superfamily
NT98_4744	COG1283	sodium-dependent phosphate transmembrane transporter activity
NT98_4745	COG0604	alcohol dehydrogenase
NT98_4746	COG1316	TRANSCRIPTIONal
NT98_4748	COG0730	response to heat
NT98_4749	COG2210	Belongs to the sulfur carrier protein TusA family
NT98_4751	COG0425	Belongs to the sulfur carrier protein TusA family
NT98_4751	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT98_4753	COG0425	Belongs to the sulfur carrier protein TusA family
NT98_4754	COG0425	Belongs to the sulfur carrier protein TusA family
NT98_4755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_4755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT98_4756	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT98_4756	COG0425	Belongs to the sulfur carrier protein TusA family
NT98_4757	COG1937	Protein conserved in bacteria
NT98_4758	COG0446	pyridine nucleotide-disulphide oxidoreductase
NT98_476	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NT98_4760	COG3591	Belongs to the peptidase S1B family
NT98_4762	COG2719	SpoVR family
NT98_4763	COG0778	Nitroreductase
NT98_4775	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_4776	COG2252	PERMEase
NT98_4778	COG2801	Transposase and inactivated derivatives
NT98_478	COG2267	carboxylic ester hydrolase activity
NT98_4780	COG1136	(ABC) transporter
NT98_4785	COG1846	Transcriptional regulator
NT98_4786	COG2814	Major facilitator Superfamily
NT98_4787	COG2205	protein histidine kinase activity
NT98_479	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NT98_4795	COG0351	phosphomethylpyrimidine kinase
NT98_4796	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT98_4798	COG2104	thiamine diphosphate biosynthetic process
NT98_4799	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NT98_48	COG1994	Peptidase M50
NT98_480	COG1522	sequence-specific DNA binding
NT98_4800	COG0352	thiamine-phosphate diphosphorylase activity
NT98_4801	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NT98_4802	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NT98_4803	COG1116	anion transmembrane transporter activity
NT98_4804	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NT98_4808	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NT98_481	COG0436	Aminotransferase
NT98_482	COG1098	S1 RNA binding domain
NT98_483	COG2155	Conserved Protein
NT98_4834	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NT98_4837	COG0581	inorganic phosphate transmembrane transporter activity
NT98_4838	COG0573	inorganic phosphate transmembrane transporter activity
NT98_4839	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NT98_4840	COG1918	ferrous iron import across plasma membrane
NT98_4840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NT98_4841	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NT98_4842	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NT98_4844	COG0531	amino acid
NT98_4845	COG0697	spore germination
NT98_4846	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NT98_4849	COG4990	cell redox homeostasis
NT98_485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NT98_4850	COG0833	amino acid
NT98_4851	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NT98_4852	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NT98_4853	COG1845	cytochrome c oxidase, subunit III
NT98_4855	COG0569	domain protein
NT98_4855	COG0475	glutathione-regulated potassium exporter activity
NT98_4856	COG2153	protein acetylation
NT98_4859	COG2252	PERMEase
NT98_4860	COG1113	amino acid transport
NT98_4863	COG1114	Component of the transport system for branched-chain amino acids
NT98_4864	COG3104	oligopeptide transport
NT98_4867	COG1476	TRANSCRIPTIONal
NT98_4868	COG3583	domain protein
NT98_4868	COG3584	3D domain protein
NT98_4869	COG0840	transmembrane signaling receptor activity
NT98_487	COG1285	pathogenesis
NT98_4875	COG3568	Endonuclease Exonuclease Phosphatase
NT98_4878	COG1063	alcohol dehydrogenase
NT98_4881	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NT98_4882	COG1879	ABC-type sugar transport system periplasmic component
NT98_4883	COG1172	Belongs to the binding-protein-dependent transport system permease family
NT98_4884	COG1129	ABC transporter
NT98_4886	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NT98_4887	COG1609	Transcriptional regulator
NT98_4888	COG0477	Major facilitator Superfamily
NT98_4889	COG1846	Transcriptional regulator
NT98_4890	COG2271	Major facilitator Superfamily
NT98_4892	COG4608	Belongs to the ABC transporter superfamily
NT98_4893	COG0601	transmembrane transport
NT98_4898	COG0659	secondary active sulfate transmembrane transporter activity
NT98_4901	COG5002	protein histidine kinase activity
NT98_4902	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NT98_4903	COG2378	regulation of single-species biofilm formation
NT98_4908	COG0833	amino acid
NT98_4909	COG0765	amino acid transport
NT98_4910	COG0765	amino acid transport
NT98_4911	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_4912	COG1126	abc transporter atp-binding protein
NT98_4913	COG1115	amino acid carrier protein
NT98_4914	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NT98_4916	COG1404	Belongs to the peptidase S8 family
NT98_4917	COG2197	response regulator
NT98_4918	COG4585	Histidine kinase
NT98_4919	COG0697	spore germination
NT98_4923	COG0366	Alpha amylase catalytic
NT98_4924	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT98_4924	COG1263	PTS System
NT98_4925	COG2188	Transcriptional regulator
NT98_4926	COG0531	amino acid
NT98_4930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT98_4931	COG0714	Associated with various cellular activities
NT98_4932	COG4548	von Willebrand factor, type A
NT98_4934	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NT98_4935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NT98_4936	COG0156	8-amino-7-oxononanoate synthase activity
NT98_4937	COG2226	methyltransferase
NT98_4939	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_4940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_4941	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_4942	COG3104	oligopeptide transport
NT98_4945	COG1620	l-lactate permease
NT98_4946	COG1027	Aspartate ammonia-lyase
NT98_4947	COG1253	flavin adenine dinucleotide binding
NT98_4948	COG0346	lactoylglutathione lyase activity
NT98_4949	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_495	COG0544	peptidyl-prolyl cis-trans isomerase activity
NT98_4950	COG1316	TRANSCRIPTIONal
NT98_4951	COG2720	vancomycin resistance protein
NT98_4955	COG3227	Zinc metalloprotease (Elastase)
NT98_4959	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NT98_4960	COG2217	Heavy metal translocating P-type atpase
NT98_4961	COG0640	Transcriptional regulator
NT98_4962	COG0531	amino acid
NT98_4965	COG2427	Protein of unknown function (DUF1641)
NT98_4966	COG3383	formate dehydrogenase (NAD+) activity
NT98_4967	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NT98_4968	COG0454	-acetyltransferase
NT98_4968	COG0456	acetyltransferase
NT98_4970	COG0745	RESPONSE REGULATOR receiver
NT98_4971	COG5002	protein histidine kinase activity
NT98_4973	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_4974	COG0697	spore germination
NT98_4976	COG0281	malic enzyme
NT98_4977	COG3493	citrate carrier protein
NT98_4978	COG4565	transcriptional regulatory protein
NT98_4979	COG3290	protein histidine kinase activity
NT98_4981	COG4990	cell redox homeostasis
NT98_4983	COG5002	protein histidine kinase activity
NT98_4984	COG0745	RESPONSE REGULATOR receiver
NT98_4989	COG2851	Citrate transporter
NT98_4990	COG4565	transcriptional regulatory protein
NT98_4991	COG3290	protein histidine kinase activity
NT98_4993	COG2268	Band 7 protein
NT98_4994	COG1585	Membrane protein implicated in regulation of membrane protease activity
NT98_4996	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NT98_4999	COG3279	Response regulator of the LytR AlgR family
NT98_50	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NT98_5000	COG3290	protein histidine kinase activity
NT98_5002	COG4512	PFAM Accessory gene regulator B
NT98_5017	COG1131	(ABC) transporter
NT98_5019	COG2766	serine protein kinase
NT98_5022	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NT98_5024	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NT98_5026	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NT98_5027	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NT98_5052	COG0735	belongs to the Fur family
NT98_5053	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NT98_5057	COG4555	ABC transporter
NT98_5059	COG0069	glutamate synthase activity
NT98_5059	COG0070	glutamate synthase
NT98_5059	COG0067	glutamate synthase
NT98_5060	COG4129	membrane
NT98_5061	COG1132	(ABC) transporter
NT98_5066	COG1194	a g-specific adenine glycosylase
NT98_5067	COG1988	membrane-bound metal-dependent
NT98_5073	COG1090	epimerase
NT98_5074	COG1228	amidohydrolase
NT98_5078	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NT98_5081	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NT98_5081	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NT98_5083	COG0463	Glycosyl transferase, family 2
NT98_5087	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NT98_5088	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT98_5088	COG1263	PTS System
NT98_5089	COG2066	Belongs to the glutaminase family
NT98_5094	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NT98_5095	COG0833	amino acid
NT98_5097	COG3829	transcription factor binding
NT98_51	COG0584	glycerophosphoryl diester phosphodiesterase
NT98_5101	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NT98_5105	COG0535	radical SAM domain protein
NT98_5107	COG0387	Pfam Sodium calcium exchanger
NT98_5108	COG3871	stress protein (general stress protein 26)
NT98_5111	COG0586	Pfam SNARE associated Golgi protein
NT98_5113	COG0681	Belongs to the peptidase S26 family
NT98_5115	COG0697	spore germination
NT98_5116	COG2217	Heavy metal translocating P-type atpase
NT98_5117	COG1295	ribonuclease BN
NT98_5119	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NT98_5122	COG3853	Toxic anion resistance protein (TelA)
NT98_5124	COG0861	Integral membrane protein TerC family
NT98_5125	COG2310	stress, protein
NT98_5126	COG2310	stress, protein
NT98_5127	COG2310	stress, protein
NT98_5133	COG2270	Major facilitator Superfamily
NT98_5144	COG0488	(ABC) transporter
NT98_5146	COG1116	anion transmembrane transporter activity
NT98_5148	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NT98_515	COG1595	DNA-templated transcription, initiation
NT98_5151	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NT98_5157	COG1263	PTS System
NT98_5157	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NT98_5157	COG2190	(PTS) system
NT98_5158	COG0366	Alpha amylase catalytic
NT98_5159	COG0277	FAD linked oxidase domain protein
NT98_5160	COG0840	transmembrane signaling receptor activity
NT98_5162	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NT98_5163	COG0765	amino acid transport
NT98_5165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NT98_5165	COG0723	plastoquinol--plastocyanin reductase activity
NT98_5166	COG2814	Major facilitator Superfamily
NT98_5167	COG3541	Predicted nucleotidyltransferase
NT98_517	COG0039	L-malate dehydrogenase activity
NT98_5177	COG0166	Belongs to the GPI family
NT98_518	COG1404	Belongs to the peptidase S8 family
NT98_5180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NT98_5181	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_5182	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NT98_5183	COG0235	Class ii aldolase
NT98_5185	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NT98_5186	COG0450	alkyl hydroperoxide reductase
NT98_5189	COG1473	amidohydrolase
NT98_5195	COG4807	Protein conserved in bacteria
NT98_5196	COG5002	protein histidine kinase activity
NT98_5197	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NT98_5198	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NT98_5199	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NT98_52	COG0789	Transcriptional regulator
NT98_5202	COG2309	aminopeptidase activity
NT98_5203	COG2076	Multidrug Resistance protein
NT98_5204	COG1012	belongs to the aldehyde dehydrogenase family
NT98_5206	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NT98_5208	COG0546	phosphoglycolate phosphatase activity
NT98_5209	COG1597	lipid kinase activity
NT98_5213	COG4682	membrane
NT98_5214	COG1846	Transcriptional regulator
NT98_5215	COG0003	Pfam Anion-transporting ATPase
NT98_5218	COG1464	Belongs to the NlpA lipoprotein family
NT98_5219	COG2011	ABC-type metal ion transport system permease component
NT98_522	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NT98_5221	COG1335	isochorismatase
NT98_5225	COG4851	CamS sex pheromone cAM373 precursor
NT98_5227	COG0210	DNA helicase
NT98_5232	COG0151	Belongs to the GarS family
NT98_5234	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NT98_5236	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NT98_5239	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NT98_524	COG0058	SHG alpha-glucan phosphorylase activity
NT98_5241	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NT98_5242	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NT98_5243	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NT98_5247	COG0506	proline dehydrogenase activity
NT98_5248	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NT98_5253	COG1215	transferase activity, transferring glycosyl groups
NT98_5257	COG2226	methyltransferase
NT98_5265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NT98_5271	COG5002	protein histidine kinase activity
NT98_5273	COG2252	PERMEase
NT98_5275	COG0459	protein refolding
NT98_5277	COG1266	CAAX protease self-immunity
NT98_5280	COG0488	(ABC) transporter
NT98_5282	COG0456	acetyltransferase
NT98_5283	COG1214	PFAM Peptidase M22, glycoprotease
NT98_5284	COG0802	atpase or kinase
NT98_529	COG1278	Cold shock
NT98_53	COG2814	Major facilitator Superfamily
NT98_530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NT98_5303	COG2183	response to ionizing radiation
NT98_5304	COG2337	Toxic component of a toxin-antitoxin (TA) module
NT98_5305	COG0864	Transcriptional regulator
NT98_5306	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NT98_5307	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NT98_5309	COG4294	response to UV
NT98_531	COG1575	Belongs to the MenA family. Type 1 subfamily
NT98_5310	COG0705	Rhomboid family
NT98_5312	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NT98_5314	COG2814	Major facilitator Superfamily
NT98_5315	COG0531	amino acid
NT98_5317	COG0179	Fumarylacetoacetate (FAA) hydrolase
NT98_5318	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NT98_532	COG1169	isochorismate synthase
NT98_5324	COG0561	phosphatase activity
NT98_5325	COG4608	Belongs to the ABC transporter superfamily
NT98_5326	COG0444	Belongs to the ABC transporter superfamily
NT98_5328	COG0601	transmembrane transport
NT98_5329	COG0747	negative chemotaxis
NT98_5330	COG0747	negative chemotaxis
NT98_5332	COG0842	Transport permease protein
NT98_5333	COG0842	Transport permease protein
NT98_5333	COG1511	domain protein
NT98_5334	COG1131	(ABC) transporter
NT98_5335	COG2197	response regulator
NT98_5336	COG4585	Histidine kinase
NT98_5337	COG0488	(ABC) transporter
NT98_534	COG0596	Alpha beta hydrolase
NT98_5340	COG5298	Protein conserved in bacteria
NT98_5343	COG0084	hydrolase, TatD family'
NT98_5346	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_5348	COG1609	Transcriptional regulator
NT98_535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NT98_5350	COG0204	Acyl-transferase
NT98_5352	COG0697	spore germination
NT98_5355	COG1910	domain protein
NT98_5356	COG0725	ABC transporter, periplasmic molybdate-binding protein
NT98_5357	COG4149	molybdate abc transporter
NT98_5360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NT98_5361	COG0656	L-ascorbic acid biosynthetic process
NT98_5362	COG4166	transmembrane transport
NT98_5363	COG4166	transmembrane transport
NT98_5365	COG4166	transmembrane transport
NT98_5366	COG4608	Belongs to the ABC transporter superfamily
NT98_5367	COG0444	Belongs to the ABC transporter superfamily
NT98_5368	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NT98_5369	COG0601	transmembrane transport
NT98_537	COG4948	Mandelate Racemase Muconate Lactonizing
NT98_5373	COG2814	Major facilitator Superfamily
NT98_5376	COG2271	Major facilitator Superfamily
NT98_5377	COG0277	FAD linked oxidase domain protein
NT98_5380	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_5387	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NT98_5389	COG4856	YbbR-like protein
NT98_5390	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NT98_54	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NT98_5408	COG0726	polysaccharide deacetylase
NT98_5409	COG2194	sulfuric ester hydrolase activity
NT98_5411	COG0489	protein tyrosine kinase activity
NT98_5412	COG0860	N-Acetylmuramoyl-L-alanine amidase
NT98_5417	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NT98_5424	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NT98_5426	COG0024	Methionine aminopeptidase
NT98_5428	COG0201	protein transport
NT98_543	COG3964	amidohydrolase
NT98_5433	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NT98_5454	COG1358	cellular component organization or biogenesis
NT98_5457	COG2813	Specifically methylates the guanine in position
NT98_5462	COG0250	Participates in transcription elongation, termination and antitermination
NT98_5463	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NT98_5465	COG3688	RNA-binding protein containing a PIN domain
NT98_5466	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NT98_5469	COG1045	serine acetyltransferase
NT98_5473	COG4956	integral membrane protein (PIN domain superfamily)
NT98_5475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NT98_5476	COG0542	response to heat
NT98_5478	COG3880	PFAM UvrB UvrC protein
NT98_5497	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NT98_5498	COG1396	sequence-specific DNA binding
NT98_5499	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NT98_5500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NT98_5501	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NT98_5502	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NT98_5503	COG0512	Glutamine amidotransferase of anthranilate synthase
NT98_5504	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NT98_5505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NT98_5508	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NT98_5511	COG2208	phosphoserine phosphatase activity
NT98_5514	COG1098	S1 RNA binding domain
NT98_5518	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NT98_5519	COG3956	TIGRFAM MazG family protein
NT98_552	COG0577	efflux transmembrane transporter activity
NT98_5520	COG2244	polysaccharide biosynthetic process
NT98_5521	COG2002	toxin-antitoxin pair type II binding
NT98_5522	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NT98_5525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NT98_5528	COG0251	oxidation-reduction process
NT98_5529	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NT98_553	COG1136	(ABC) transporter
NT98_5532	COG4466	Protein conserved in bacteria
NT98_5535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NT98_5536	COG0084	hydrolase, TatD family'
NT98_5538	COG2002	toxin-antitoxin pair type II binding
NT98_5539	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NT98_554	COG0577	efflux transmembrane transporter activity
NT98_5541	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NT98_5543	COG1774	PSP1 C-terminal conserved region
NT98_5544	COG0470	DNA polymerase III
NT98_5546	COG1982	Orn Lys Arg decarboxylase major
NT98_555	COG0577	efflux transmembrane transporter activity
NT98_5558	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NT98_5559	COG0590	tRNA wobble adenosine to inosine editing
NT98_556	COG2205	protein histidine kinase activity
NT98_5560	COG1335	isochorismatase
NT98_5561	COG1428	Deoxynucleoside kinase
NT98_5562	COG1428	Deoxynucleoside kinase
NT98_5568	COG1686	Belongs to the peptidase S11 family
NT98_5569	COG0516	GMP reductase activity
NT98_5569	COG0517	IMP dehydrogenase activity
NT98_557	COG0745	RESPONSE REGULATOR receiver
NT98_5579	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NT98_558	COG0640	Transcriptional regulator
NT98_5580	COG0187	DNA topoisomerase II activity
NT98_5582	COG2501	S4 domain
NT98_5583	COG0592	DNA-directed DNA polymerase activity
NT98_5587	COG0706	membrane insertase activity
NT98_5588	COG1847	R3H domain protein
NT98_559	COG5658	integral membrane protein
NT98_5593	COG1192	Involved in chromosome partitioning
NT98_5594	COG1475	DNA binding
NT98_5596	COG0668	transmembrane transport
NT98_5597	COG4481	Protein conserved in bacteria
NT98_5598	COG0012	GTP binding
NT98_560	COG3708	Transcriptional regulator
NT98_560	COG2207	Transcriptional regulator
NT98_5600	COG0629	single-stranded DNA binding
NT98_5602	COG4241	membrane
NT98_5603	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NT98_5605	COG0305	Participates in initiation and elongation during chromosome replication
NT98_561	COG1136	(ABC) transporter
NT98_5611	COG0745	RESPONSE REGULATOR receiver
NT98_5612	COG5002	protein histidine kinase activity
NT98_5613	COG4863	YycH protein
NT98_5614	COG4853	Protein conserved in bacteria
NT98_5615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NT98_5616	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT98_562	COG0577	efflux transmembrane transporter activity
NT98_5621	COG1164	Oligoendopeptidase f
NT98_5626	COG1272	protein, Hemolysin III
NT98_5627	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NT98_5631	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NT98_5632	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NT98_5633	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NT98_5634	COG2814	Major facilitator Superfamily
NT98_5635	COG3275	phosphorelay sensor kinase activity
NT98_5636	COG3279	Response regulator of the LytR AlgR family
NT98_5639	COG0628	permease
NT98_5640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NT98_5640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NT98_5641	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NT98_5642	COG1309	transcriptional regulator
NT98_5643	COG0463	Glycosyl transferase, family 2
NT98_5647	COG0488	(ABC) transporter
NT98_5650	COG1607	acyl-coa hydrolase
NT98_566	COG0586	Pfam SNARE associated Golgi protein
NT98_5661	COG3344	reverse transcriptase
NT98_5663	COG0681	Belongs to the peptidase S26 family
NT98_5666	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NT98_5685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NT98_5695	COG0791	NLP P60 protein
NT98_5695	COG0741	lytic transglycosylase activity
NT98_5708	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_571	COG1597	lipid kinase activity
NT98_5720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NT98_5734	COG3012	SEC-C Motif Domain Protein
NT98_5737	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NT98_5739	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NT98_5749	COG2801	Transposase and inactivated derivatives
NT98_5757	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NT98_5764	COG3944	biosynthesis protein
NT98_5765	COG0489	protein tyrosine kinase activity
NT98_5767	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NT98_5768	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NT98_5769	COG2089	acid synthase
NT98_577	COG0745	RESPONSE REGULATOR receiver
NT98_5771	COG1083	cytidylyl-transferase
NT98_5779	COG1649	PFAM Uncharacterised BCR, COG1649
NT98_578	COG5002	protein histidine kinase activity
NT98_5783	COG2801	Transposase and inactivated derivatives
NT98_5787	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NT98_5791	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT98_58	COG1619	proteins homologs of microcin C7 resistance protein MccF
NT98_5800	COG2801	Transposase and inactivated derivatives
NT98_5818	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NT98_5822	COG0745	RESPONSE REGULATOR receiver
NT98_5825	COG0577	efflux transmembrane transporter activity
NT98_5826	COG1136	(ABC) transporter
NT98_5836	COG4644	lycopene metabolic process
NT98_5837	COG4644	lycopene metabolic process
NT98_584	COG1842	Phage shock protein A
NT98_5858	COG1780	Probably involved in ribonucleotide reductase function
NT98_5867	COG0582	viral genome integration into host DNA
NT98_589	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_5893	COG1484	DNA-dependent DNA replication
NT98_59	COG4506	Protein conserved in bacteria
NT98_5911	COG1396	sequence-specific DNA binding
NT98_5918	COG1192	Involved in chromosome partitioning
NT98_594	COG1294	oxidase, subunit
NT98_5948	COG5484	DNA packaging
NT98_5948	COG3728	DNA packaging
NT98_595	COG1271	oxidase subunit
NT98_597	COG0288	reversible hydration of carbon dioxide
NT98_607	COG0494	nUDIX hydrolase
NT98_609	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NT98_61	COG1595	DNA-templated transcription, initiation
NT98_612	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NT98_613	COG1116	anion transmembrane transporter activity
NT98_614	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NT98_617	COG1368	sulfuric ester hydrolase activity
NT98_618	COG2267	carboxylic ester hydrolase activity
NT98_619	COG4191	Histidine kinase
NT98_620	COG5002	protein histidine kinase activity
NT98_635	COG0521	Mo-molybdopterin cofactor biosynthetic process
NT98_637	COG0438	transferase activity, transferring glycosyl groups
NT98_638	COG0671	phosphoesterase, PA-phosphatase related
NT98_639	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NT98_640	COG2267	carboxylic ester hydrolase activity
NT98_646	COG1794	racemase activity, acting on amino acids and derivatives
NT98_648	COG1131	(ABC) transporter
NT98_649	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NT98_650	COG1242	4 iron, 4 sulfur cluster binding
NT98_654	COG1136	(ABC) transporter
NT98_656	COG0582	viral genome integration into host DNA
NT98_657	COG0490	domain, Protein
NT98_658	COG0475	glutathione-regulated potassium exporter activity
NT98_659	COG2814	Major facilitator Superfamily
NT98_66	COG2234	aminopeptidase activity
NT98_667	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NT98_669	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NT98_67	COG0024	Methionine aminopeptidase
NT98_673	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NT98_674	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NT98_676	COG0303	'Molybdopterin
NT98_677	COG1763	Mo-molybdopterin cofactor biosynthetic process
NT98_678	COG0314	molybdopterin synthase activity
NT98_68	COG1131	(ABC) transporter
NT98_683	COG1329	Transcriptional regulator
NT98_687	COG3832	glyoxalase III activity
NT98_689	COG2814	Major facilitator Superfamily
NT98_69	COG0842	Transport permease protein
NT98_690	COG2081	HI0933 family
NT98_691	COG2244	polysaccharide biosynthetic process
NT98_692	COG1187	pseudouridine synthase activity
NT98_693	COG1349	DNA-binding transcription factor activity
NT98_694	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NT98_696	COG1523	belongs to the glycosyl hydrolase 13 family
NT98_697	COG0510	thiamine kinase activity
NT98_7	COG0477	Major facilitator Superfamily
NT98_70	COG4585	Histidine kinase
NT98_700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NT98_702	COG1363	Peptidase, m42
NT98_703	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NT98_704	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NT98_706	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NT98_709	COG1674	ftsk spoiiie
NT98_71	COG2197	response regulator
NT98_713	COG1695	Transcriptional regulator
NT98_714	COG0789	Transcriptional regulator
NT98_715	COG0697	spore germination
NT98_716	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_720	COG2309	aminopeptidase activity
NT98_722	COG3118	belongs to the thioredoxin family
NT98_723	COG4851	CamS sex pheromone cAM373 precursor
NT98_724	COG1609	Transcriptional regulator
NT98_730	COG3279	Response regulator of the LytR AlgR family
NT98_734	COG2972	Histidine kinase
NT98_734	COG0745	RESPONSE REGULATOR receiver
NT98_736	COG2267	carboxylic ester hydrolase activity
NT98_737	COG0123	including yeast histone deacetylase and acetoin utilization protein
NT98_738	COG0517	IMP dehydrogenase activity
NT98_739	COG0454	-acetyltransferase
NT98_740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NT98_741	COG0110	maltose O-acetyltransferase activity
NT98_75	COG5001	Diguanylate cyclase
NT98_75	COG3300	MHYT domain
NT98_750	COG0626	cystathionine gamma-synthase activity
NT98_751	COG1956	GAF domain-containing protein
NT98_752	COG1309	transcriptional regulator
NT98_753	COG0697	spore germination
NT98_754	COG0583	DNA-binding transcription factor activity
NT98_756	COG1104	cysteine desulfurase activity
NT98_759	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NT98_761	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NT98_762	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NT98_764	COG3874	Sporulation protein YtfJ
NT98_765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NT98_766	COG0827	DNA restriction-modification system
NT98_77	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NT98_771	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NT98_779	COG0589	response to stress
NT98_78	COG2181	nitrate reductase activity
NT98_78	COG0247	lactate metabolic process
NT98_780	COG1028	Short-chain dehydrogenase reductase Sdr
NT98_783	COG1476	TRANSCRIPTIONal
NT98_785	COG0662	Cupin 2, conserved barrel domain protein
NT98_786	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NT98_79	COG0183	Belongs to the thiolase family
NT98_794	COG0006	proline dipeptidase activity
NT98_797	COG4109	DRTGG domain
NT98_799	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NT98_8	COG3279	Response regulator of the LytR AlgR family
NT98_80	COG1250	3-hydroxyacyl-CoA dehydrogenase
NT98_802	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NT98_805	COG0587	DNA-directed DNA polymerase activity
NT98_806	COG0281	malic enzyme
NT98_807	COG1725	Transcriptional regulator
NT98_81	COG1960	acyl-CoA dehydrogenase activity
NT98_812	COG3030	protein affecting phage T7 exclusion by the F plasmid
NT98_813	COG0628	permease
NT98_815	COG0372	Belongs to the citrate synthase family
NT98_816	COG0538	isocitrate dehydrogenase activity
NT98_82	COG1960	acyl-CoA dehydrogenase activity
NT98_821	COG0745	RESPONSE REGULATOR receiver
NT98_822	COG5002	protein histidine kinase activity
NT98_823	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NT98_823	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NT98_825	COG1971	Probably functions as a manganese efflux pump
NT98_826	COG0237	dephospho-CoA kinase activity
NT98_827	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NT98_829	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NT98_831	COG3611	Membrane attachment protein
NT98_832	COG1484	DNA-dependent DNA replication
NT98_834	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NT98_835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NT98_839	COG1363	Peptidase, m42
NT98_84	COG3343	RNA polymerase activity
NT98_840	COG1309	transcriptional regulator
NT98_841	COG1566	PFAM secretion protein HlyD family protein
NT98_842	COG2814	Major facilitator Superfamily
NT98_844	COG1418	mRNA catabolic process
NT98_846	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NT98_849	COG0017	Asparaginyl-tRNA synthetase
NT98_854	COG1286	toxin biosynthetic process
NT98_855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NT98_855	COG1796	DNA polymerase
NT98_858	COG1187	pseudouridine synthase activity
NT98_859	COG1114	Component of the transport system for branched-chain amino acids
NT98_86	COG4821	SIS domain
NT98_860	COG5386	Cell surface protein
NT98_862	COG5386	Cell surface protein
NT98_865	COG1120	ATPase activity
NT98_866	COG4509	Sortase family
NT98_868	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NT98_869	COG4895	conserved protein (DUF2196)
NT98_871	COG0745	RESPONSE REGULATOR receiver
NT98_872	COG2205	protein histidine kinase activity
NT98_873	COG1131	(ABC) transporter
NT98_879	COG2318	DinB family
NT98_881	COG0318	PFAM AMP-dependent synthetase and ligase
NT98_882	COG1309	transcriptional regulator
NT98_883	COG1024	Enoyl-CoA hydratase
NT98_884	COG2086	electron transfer activity
NT98_885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NT98_886	COG3118	belongs to the thioredoxin family
NT98_888	COG1719	4-vinyl reductase, 4VR
NT98_889	COG2009	succinate dehydrogenase
NT98_89	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NT98_890	COG1053	succinate dehydrogenase
NT98_891	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NT98_892	COG0824	Thioesterase
NT98_893	COG1876	peptidase activity
NT98_895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NT98_896	COG1360	Flagellar Motor Protein
NT98_897	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NT98_898	COG4152	abc transporter atp-binding protein
NT98_899	COG1668	transmembrane transport
NT98_9	COG1966	Carbon starvation protein
NT98_90	COG1494	fructose-1,6-bisphosphatase
NT98_900	COG1959	2 iron, 2 sulfur cluster binding
NT98_902	COG0697	spore germination
NT98_903	COG1396	sequence-specific DNA binding
NT98_904	COG1983	PspC domain protein
NT98_905	COG0402	S-adenosylhomocysteine deaminase activity
NT98_906	COG2233	PERMEase
NT98_907	COG2197	response regulator
NT98_91	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NT98_94	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NT98_941	COG1309	transcriptional regulator
NT98_943	COG2814	Major facilitator Superfamily
NT98_945	COG5401	PFAM Sporulation and spore germination
NT98_948	COG0622	Phosphoesterase
NT98_95	COG2890	protein-(glutamine-N5) methyltransferase activity
NT98_958	COG0470	DNA polymerase III
NT98_958	COG1067	ATP-dependent peptidase activity
NT98_961	COG1764	response to oxidative stress
NT98_962	COG1846	Transcriptional regulator
NT98_964	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NT98_966	COG1587	Uroporphyrinogen-III synthase
NT98_967	COG0113	porphobilinogen synthase activity
NT98_969	COG1388	LysM domain
NT98_972	COG0285	dihydrofolate synthase activity
NT98_976	COG1077	Cell shape determining protein MreB Mrl
NT98_977	COG1792	Involved in formation and maintenance of cell shape
NT98_98	COG0009	L-threonylcarbamoyladenylate synthase
NT98_980	COG2894	cell division
NT98_981	COG0739	heme binding
NT98_982	COG1994	Peptidase M50
NT98_983	COG1530	ribonuclease E activity
NT98_985	COG2868	ribosomal protein
NT98_987	COG3290	protein histidine kinase activity
NT98_989	COG0745	RESPONSE REGULATOR receiver
NT98_990	COG5002	protein histidine kinase activity
NT98_991	COG1136	(ABC) transporter
NT98_992	COG0577	efflux transmembrane transporter activity
NT98_993	COG0577	efflux transmembrane transporter activity
NT98_994	COG0077	Prephenate dehydratase
NT98_995	COG2258	MOSC domain
NT98_996	COG1827	regulation of RNA biosynthetic process
NT98_997	COG1104	cysteine desulfurase activity
NT98_998	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NT98_999	COG0157	Belongs to the NadC ModD family