locus-tag class description BCAH820_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCAH820_0003 ENOG410848D S4 domain protein YaaA BCAH820_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCAH820_0012 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCAH820_0019 ENOG4105ZMH deoxynucleoside kinase BCAH820_0021 ENOG4105GTG Isochorismatase BCAH820_0022 ENOG4108Z6B deaminase BCAH820_0023 ENOG4105C6E dna polymerase iii BCAH820_0027 ENOG41067KS pro-sigma K processing BCAH820_0034 ENOG4105CXN decarboxylase BCAH820_0036 ENOG4105FA2 dna polymerase iii BCAH820_0037 ENOG4105MA4 psp1 domain protein BCAH820_0039 ENOG41060K3 Methyltransferase BCAH820_0041 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCAH820_0042 ENOG4105KRN Transcriptional regulator, abrb family BCAH820_0044 ENOG4105F8V Hydrolase, tatD family BCAH820_0045 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCAH820_0047 ENOG4105XFA sporulation peptidase YabG BCAH820_0048 ENOG4105W42 Veg protein BCAH820_0051 ENOG4105DFT pur operon repressor BCAH820_0053 ENOG4105KME endoribonuclease L-psp BCAH820_0056 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCAH820_0059 ENOG4108JA2 transcriptioN-repair coupling factor BCAH820_0060 ENOG4108M14 stage v sporulation protein t BCAH820_0062 ENOG4108IY2 MazG family BCAH820_0063 ENOG41082I2 s4 domain protein BCAH820_0064 ENOG4105VYY sporulation protein yabp BCAH820_0067 ENOG41060GV RNA binding s1 domain protein BCAH820_0072 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCAH820_0073 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCAH820_0076 ENOG4105C6T cysteine synthase BCAH820_0077 ENOG4105CRQ synthase (Component I) BCAH820_0078 ENOG4105DDQ anthranilate synthase BCAH820_0079 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCAH820_0080 ENOG4105EEI dihydropteroate synthase BCAH820_0081 ENOG4105KRF dihydroneopterin aldolase BCAH820_0082 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCAH820_0084 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCAH820_0089 ENOG4108Z0C Uvrb UvrC protein BCAH820_0092 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCAH820_0094 ENOG4105CTP PilT protein domain protein BCAH820_0095 ENOG4105CTP PilT protein domain protein BCAH820_0099 ENOG4105D7W serine acetyltransferase BCAH820_0102 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCAH820_0103 ENOG4105M0M Tetracycline resistance protein BCAH820_0104 ENOG4105QIV RNA polymerase BCAH820_0106 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCAH820_0107 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCAH820_0112 ENOG4107Y49 methyltransferase BCAH820_0113 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BCAH820_0116 ENOG4105XPM ribosomal protein BCAH820_0137 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCAH820_0142 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCAH820_0145 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCAH820_0147 ENOG41067V7 50S ribosomal protein L36 BCAH820_0153 ENOG4108JJB ABC transporter BCAH820_0154 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCAH820_0155 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BCAH820_0160 ENOG4105D1F ATP-binding protein BCAH820_0163 ENOG4108NMV polysaccharide deacetylase BCAH820_0178 ENOG4105C8B TIGR00159 family BCAH820_0179 ENOG4107U5W ybbr family BCAH820_0181 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BCAH820_0182 ENOG4108VQT Alpha beta hydrolase fold protein BCAH820_0184 ENOG4105CMG Carbohydrate kinase BCAH820_0186 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BCAH820_0187 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BCAH820_0193 ENOG4108PSK reductase BCAH820_0194 ENOG4108UMI ABC transporter, permease BCAH820_0196 ENOG4105D01 (LipO)protein BCAH820_0197 ENOG4105CPQ Dehydrogenase BCAH820_0199 ENOG4105IQ5 FAD linked oxidase domain protein BCAH820_0202 ENOG4105C2C drug resistance transporter, Bcr CflA BCAH820_0205 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCAH820_0206 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCAH820_0207 ENOG4105C3U ABC transporter BCAH820_0208 ENOG4108JQ7 (ABC) transporter BCAH820_0214 ENOG4108J59 Extracellular solute-binding protein, family 5 BCAH820_0215 ENOG4108J59 Extracellular solute-binding protein, family 5 BCAH820_0217 ENOG4105II7 pyrroline-5-carboxylate reductase BCAH820_0218 ENOG4107XDY Nicotinamide Mononucleotide Transporter BCAH820_0220 ENOG4105E0C molybdate abc transporter BCAH820_0221 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCAH820_0222 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCAH820_0226 ENOG4105F6E Acyl-transferase BCAH820_0228 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCAH820_0231 ENOG4108RE7 deoxyribonuclease BCAH820_0232 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCAH820_0238 ENOG4105C5H ABC transporter BCAH820_0241 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCAH820_0243 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCAH820_0244 ENOG4105C3U ABC transporter BCAH820_0245 ENOG4108JQ7 (ABC) transporter BCAH820_0246 ENOG410667J hydrolase BCAH820_0253 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCAH820_0254 ENOG4105ERH Fumarylacetoacetate hydrolase BCAH820_0256 ENOG4108SC4 )-transporter BCAH820_0257 ENOG4105CPF Cell wall formation (By similarity) BCAH820_0258 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCAH820_0260 ENOG4107ZXI Rhomboid family BCAH820_0263 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCAH820_0264 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCAH820_0266 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCAH820_0284 ENOG4105K8N protein family UPF0079, ATPase BCAH820_0285 ENOG41072GX Peptidase M22 Glycoprotease BCAH820_0286 ENOG410801F ribosomal-protein-alanine acetyltransferase BCAH820_0287 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCAH820_0288 ENOG4105C5H ABC transporter BCAH820_0291 ENOG4108TYN CAAX amino terminal protease family protein BCAH820_0295 ENOG4105C7N Xanthine uracil vitamin C permease BCAH820_0297 ENOG4105BZU Histidine kinase BCAH820_0301 ENOG4107ZXU DSBA oxidoreductase BCAH820_0310 ENOG4108SHN Glycosyl transferase, family 2 BCAH820_0317 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_0320 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCAH820_0321 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCAH820_0322 ENOG4105C83 adenylosuccinate lyase BCAH820_0324 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCAH820_0329 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCAH820_0331 ENOG4105C12 Phosphoribosylglycinamide synthetase BCAH820_0336 ENOG4105C4R Atp-dependent dna helicase BCAH820_0342 ENOG4108W2Y isochorismatase BCAH820_0343 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCAH820_0344 ENOG4108UMI ABC transporter, permease BCAH820_0345 ENOG4105D01 (LipO)protein BCAH820_0350 ENOG410834F Transcriptional regulator BCAH820_0351 ENOG4107I77 yiaA/B two helix domain BCAH820_0355 ENOG4105CBD Diacylglycerol kinase BCAH820_0356 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BCAH820_0357 ENOG4108JPW Aminotransferase BCAH820_0359 ENOG4105C26 Dehydrogenase BCAH820_0360 ENOG4105KPY Small multidrug resistance protein BCAH820_0364 ENOG4105D9N nucleoside BCAH820_0365 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCAH820_0367 ENOG4105BZU Histidine kinase BCAH820_0368 ENOG4108W15 Protein of unknown function (DUF1456) BCAH820_0371 ENOG4105DTQ mandelate racemase muconate lactonizing BCAH820_0372 ENOG4105DFD Na H antiporter BCAH820_0377 ENOG4105D3R alkyl hydroperoxide reductase BCAH820_0378 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BCAH820_0380 ENOG4107W7X Aldolase BCAH820_0381 ENOG4105EHG Permease protein BCAH820_0382 ENOG4105DQ5 transport system permease protein BCAH820_0383 ENOG4108V5C ABC transporter BCAH820_0387 ENOG4106UIA BCAH820_0388 ENOG4106UIA BCAH820_0393 ENOG4105BZU Histidine kinase BCAH820_0397 ENOG410756H nucleotidyltransferase BCAH820_0398 ENOG4105D2S major facilitator superfamily BCAH820_0401 ENOG4105E5Q amino acid AbC transporter BCAH820_0402 ENOG4105EAB amino acid AbC transporter BCAH820_0405 ENOG4105C8Q Methyl-accepting chemotaxis BCAH820_0410 ENOG4105C5B carbamate kinase BCAH820_0414 ENOG4105CI1 PTS System BCAH820_0421 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCAH820_0424 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCAH820_0427 ENOG4105C5H ABC transporter BCAH820_0433 ENOG41062JF Transcriptional regulator BCAH820_0437 ENOG4105DEU major facilitator superfamily BCAH820_0443 ENOG4108N0M stress protein BCAH820_0444 ENOG4106FN3 tellurium resistance protein BCAH820_0445 ENOG4106FN3 tellurium resistance protein BCAH820_0446 ENOG4107TS3 membrane protein, TerC BCAH820_0447 ENOG4108TTB tellurium resistance protein BCAH820_0451 ENOG4105KJF protein tyrosine phosphatase BCAH820_0453 ENOG4107U9T Pfam:Ribonuclease_BN BCAH820_0455 ENOG4105C59 p-type ATPase BCAH820_0456 ENOG4108IPJ Membrane BCAH820_0461 ENOG4107ZTW SNARE associated Golgi BCAH820_0464 ENOG410606W general stress protein BCAH820_0465 ENOG4105UPD Calcium Proton BCAH820_0472 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCAH820_0473 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BCAH820_0480 ENOG4105CSV Glutaminase BCAH820_0483 ENOG4108A04 Beta-lactamase BCAH820_0486 ENOG4105CKK Glycosyl transferase, family 2 BCAH820_0487 ENOG4107QQG Dehydrogenase BCAH820_0488 ENOG4105C3I Nad-dependent epimerase dehydratase BCAH820_0491 ENOG4105F1A Pyruvate formate-lyase BCAH820_0495 ENOG4105CI2 imidazolone-5-propionate hydrolase BCAH820_0496 ENOG4105ECP epimerase BCAH820_0502 ENOG41067AE Membrane-bound metal-dependent hydrolase BCAH820_0503 ENOG4105CEN a g-specific adenine glycosylase BCAH820_0504 ENOG4106BXE BCAH820_0511 ENOG4105BZ1 (ABC) transporter BCAH820_0512 ENOG4107NBY Membrane BCAH820_0513 ENOG4105CBC glutamate synthase BCAH820_0515 ENOG4108IUW ABC transporter BCAH820_0519 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCAH820_0520 ENOG4105G5W regulator Fur family BCAH820_0543 ENOG4108JQC penicillin-binding protein 1A BCAH820_0544 ENOG4107ZQN disulfide bond BCAH820_0546 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCAH820_0548 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCAH820_0549 ENOG4105BZU Histidine kinase BCAH820_0550 ENOG4105CYN Serine protein kinase BCAH820_0562 ENOG4105CDU Replicative dna helicase BCAH820_0567 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BCAH820_0584 ENOG4105CAR Terminase, large subunit BCAH820_0606 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BCAH820_0610 ENOG4105C94 Transporter BCAH820_0613 ENOG4105DZ6 Band 7 protein BCAH820_0615 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCAH820_0616 ENOG4108V9W transcriptional regulatory protein BCAH820_0617 ENOG4105D4T Citrate transporter BCAH820_0621 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCAH820_0622 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCAH820_0623 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCAH820_0624 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCAH820_0625 ENOG4105BZ7 extracellular solute-binding protein family 1 BCAH820_0626 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCAH820_0627 ENOG4108STX response regulator BCAH820_0628 ENOG4105US7 Histidine kinase BCAH820_0633 ENOG4108MRH transcriptional regulatory protein BCAH820_0635 ENOG4105C6K Malic enzyme BCAH820_0637 ENOG4108UZ3 Transporter BCAH820_0638 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCAH820_0640 ENOG4105BZU Histidine kinase BCAH820_0641 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_0643 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCAH820_0644 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCAH820_0645 ENOG4108JB9 formate dehydrogenase BCAH820_0650 ENOG4105CUB amino acid BCAH820_0652 ENOG4105C59 p-type ATPase BCAH820_0653 ENOG4105DAP Nicotinate phosphoribosyltransferase BCAH820_0660 ENOG41073R8 VanW family BCAH820_0661 ENOG4108KGH TRANSCRIPTIONal BCAH820_0662 ENOG4105D9N nucleoside BCAH820_0663 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCAH820_0664 ENOG4105C37 (CBS) domain BCAH820_0665 ENOG4108IJ0 Aspartate ammonia-lyase BCAH820_0666 ENOG4105DAA L-lactate BCAH820_0669 ENOG4105DUX Transporter BCAH820_0670 ENOG4108MES Periplasmic binding protein BCAH820_0671 ENOG4105DQ5 transport system permease protein BCAH820_0672 ENOG4108IHU transport system permease protein BCAH820_0673 ENOG4105E0A ABC, transporter BCAH820_0674 ENOG4105DMQ Methyltransferase BCAH820_0676 ENOG4105EXW epimerase dehydratase BCAH820_0678 ENOG4107T89 von Willebrand factor, type A BCAH820_0679 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCAH820_0680 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCAH820_0683 ENOG4105BZU Histidine kinase BCAH820_0684 ENOG4105D5Q Arginine ornithine antiporter BCAH820_0685 ENOG4107414 GntR family transcriptional regulator BCAH820_0686 ENOG4105C5Y PTS System BCAH820_0687 ENOG4105CG3 alpha amylase, catalytic region BCAH820_0691 ENOG4105E1K spore germination protein BCAH820_0693 ENOG4105CRN Aminoglycoside phosphotransferase BCAH820_0694 ENOG4105BZG amino acid carrier protein BCAH820_0695 ENOG4105BZG amino acid carrier protein BCAH820_0696 ENOG4105CDA abc transporter atp-binding protein BCAH820_0697 ENOG4105CT1 (ABC) transporter BCAH820_0698 ENOG4105EAD ABC transporter BCAH820_0699 ENOG4105DRP amino acid AbC transporter BCAH820_0700 ENOG4108IQI permease BCAH820_0703 ENOG4105GFR rna polymerase sigma factor BCAH820_0705 ENOG4105D29 Helix-turn-helix type 11 domain protein BCAH820_0706 ENOG4105NAE bifunctional deaminase-reductase domain protein BCAH820_0707 ENOG4105BZU Histidine kinase BCAH820_0710 ENOG4105CHH sulfate transporter BCAH820_0711 ENOG41068KF Universal stress protein BCAH820_0713 ENOG4105DEF Extracellular solute-binding protein, family 5 BCAH820_0715 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCAH820_0716 ENOG4108JQ7 (ABC) transporter BCAH820_0718 ENOG4105CXY transporter BCAH820_0719 ENOG41067TZ transcriptional regulator, MarR family BCAH820_0720 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_0721 ENOG4105ETE Transcriptional regulator (LacI family BCAH820_0722 ENOG4108RVA ribokinase BCAH820_0724 ENOG4105C2J ABC transporter BCAH820_0725 ENOG4105CNN ABC, transporter BCAH820_0726 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCAH820_0727 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCAH820_0739 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCAH820_0740 ENOG41069ER domain protein BCAH820_0741 ENOG4105VZ8 Transcriptional regulator BCAH820_0742 ENOG4107D63 BCAH820_0744 ENOG4105DUX Transporter BCAH820_0748 ENOG4105C85 amino acid BCAH820_0749 ENOG4105C7N Xanthine uracil vitamin C permease BCAH820_0752 ENOG4105MA6 gCN5-related N-acetyltransferase BCAH820_0757 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCAH820_0758 ENOG4105E2S oxidase) subunit II BCAH820_0761 ENOG4106CAD Protein of unknown function (DUF3311) BCAH820_0762 ENOG4105E1V na solute symporter BCAH820_0765 ENOG4108NHD germination protein BCAH820_0767 ENOG4105CE1 Ferrous iron transport protein b BCAH820_0768 ENOG4105CE1 Ferrous iron transport protein b BCAH820_0769 ENOG4105CE1 Ferrous iron transport protein b BCAH820_0770 ENOG4105CVA phosphate BCAH820_0771 ENOG4105C8U phosphate abc transporter BCAH820_0772 ENOG4105E2Z phosphate ABC transporter (Permease BCAH820_0797 ENOG41080XQ Signal transduction protein with cbs domains BCAH820_0802 ENOG4105ETU transcriptional activator (TenA BCAH820_0804 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCAH820_0806 ENOG4108VEU Thiamine monophosphate synthase BCAH820_0807 ENOG41080HI glycine oxidase BCAH820_0810 ENOG4105D06 uba thif-type nad fad binding protein BCAH820_0811 ENOG4105DWF phosphomethylpyrimidine kinase BCAH820_0820 ENOG4108INS Transcriptional regulator BCAH820_0823 ENOG4105C7N Xanthine uracil vitamin C permease BCAH820_0825 ENOG4108PXI ErfK YbiS YcfS YnhG BCAH820_0832 ENOG4108B31 Spore germination protein BCAH820_0837 ENOG4107Y03 Nitroreductase BCAH820_0838 ENOG4105ED1 spovr family BCAH820_0843 ENOG4107SCJ type I restriction enzyme EcoKI subunit R BCAH820_0848 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCAH820_0849 ENOG4107Y5K Resolvase BCAH820_0857 ENOG4105ED1 spovr family BCAH820_0859 ENOG4107UNZ domain protein BCAH820_0862 ENOG4105ED1 spovr family BCAH820_0864 ENOG4105ED1 spovr family BCAH820_0866 ENOG4108TCS Glutamyl endopeptidase BCAH820_0868 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BCAH820_0869 ENOG4105XTG Pfam:DUF156 BCAH820_0870 ENOG4105VFE sira family BCAH820_0871 ENOG4107TPS domain protein BCAH820_0872 ENOG4105VFE sira family BCAH820_0873 ENOG41085GJ domain protein BCAH820_0875 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCAH820_0876 ENOG41087NI Sulfite exporter TauE/SafE BCAH820_0878 ENOG4108KGH TRANSCRIPTIONal BCAH820_0883 ENOG4105EMD TRANSCRIPTIONal BCAH820_0884 ENOG4105VCP PTS System BCAH820_0885 ENOG4105VZJ PTS System BCAH820_0886 ENOG4105CK1 PTS System BCAH820_0891 ENOG41069ER domain protein BCAH820_0892 ENOG4107RBB ABC transporter, permease BCAH820_0893 ENOG4105C19 ABC transporter BCAH820_0899 ENOG4105WEF catalase BCAH820_0906 ENOG4107T5V SNARE associated Golgi BCAH820_0914 ENOG4105CUB amino acid BCAH820_0915 ENOG4107RWR Sodium hydrogen exchanger BCAH820_0917 ENOG4106KNT transcriptional regulator BCAH820_0925 ENOG4108YXU transcriptional regulator AsnC family BCAH820_0927 ENOG4105KPY Small multidrug resistance protein BCAH820_0928 ENOG4105KPY Small multidrug resistance protein BCAH820_0933 ENOG4105NF4 modulator of drug activity BCAH820_0935 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCAH820_0936 ENOG4105E5W Transporter BCAH820_0938 ENOG4107RKG DJ-1/PfpI family BCAH820_0939 ENOG4105CH6 catalase BCAH820_0941 ENOG4105D5Q Arginine ornithine antiporter BCAH820_0942 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BCAH820_0944 ENOG4105C26 Dehydrogenase BCAH820_0945 ENOG4105BZ1 (ABC) transporter BCAH820_0946 ENOG4105BZ1 (ABC) transporter BCAH820_0948 ENOG4105DRP amino acid AbC transporter BCAH820_0949 ENOG4105CDA abc transporter atp-binding protein BCAH820_0952 ENOG410839P BCAH820_0959 ENOG4107FQX Alpha-acetolactate decarboxylase BCAH820_0963 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCAH820_0964 ENOG4105D4P Coproporphyrinogen iii oxidase BCAH820_0967 ENOG4105CHH sulfate transporter BCAH820_0975 ENOG4106AKK s-layer domain-containing protein BCAH820_0977 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCAH820_0979 ENOG4105CGU Enoyl-CoA hydratase BCAH820_0985 ENOG4105DER m42 family BCAH820_0989 ENOG4105CTU Proline racemase BCAH820_0998 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCAH820_1000 ENOG4108JQ7 (ABC) transporter BCAH820_1003 ENOG4105CSH Transporter BCAH820_1005 ENOG4108MRH transcriptional regulatory protein BCAH820_1024 ENOG4105CDU Replicative dna helicase BCAH820_1028 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_1041 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCAH820_1047 ENOG4105CMT Dihydroxyacetone kinase BCAH820_1049 ENOG4105CMT Dihydroxyacetone kinase BCAH820_1052 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCAH820_1066 ENOG4105WN5 stage II sporulation protein BCAH820_1068 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_1070 ENOG4108MJI response regulator BCAH820_1071 ENOG4105BZU Histidine kinase BCAH820_1072 ENOG4105BZU Histidine kinase BCAH820_1077 ENOG4105K8R UPF0145 protein BCAH820_1084 ENOG4107VRP DNA repair exonuclease BCAH820_1085 ENOG4106D4I domain protein BCAH820_1100 ENOG4108MUZ hydrolase BCAH820_1104 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCAH820_1107 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCAH820_1110 ENOG4105EMN RNA polymerase sigma factor BCAH820_1112 ENOG4105CNI cell division protein FtsW BCAH820_1115 ENOG4105C57 major facilitator superfamily BCAH820_1116 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_1118 ENOG4105EEM helicase BCAH820_1119 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCAH820_1124 ENOG4105K59 histidine triad (HIT) protein BCAH820_1139 ENOG410905X membrane-flanked domain protein BCAH820_1140 ENOG4105CKV Membrane BCAH820_1148 ENOG410905X membrane-flanked domain protein BCAH820_1149 ENOG4105CKV Membrane BCAH820_1150 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCAH820_1151 ENOG4105BZ4 penicillin-binding protein BCAH820_1154 ENOG4105C1Q protoporphyrinogen oxidase BCAH820_1160 ENOG4105ECB domain protein BCAH820_1163 ENOG4108MK9 spermidine N(1)-acetyltransferase BCAH820_1165 ENOG4106AXD BCAH820_1166 ENOG4108RQ5 Beta-lactamase domain-containing protein BCAH820_1167 ENOG4105DF9 Lipoate-protein, ligase BCAH820_1169 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_1178 ENOG4105CNA YD repeat protein BCAH820_1181 ENOG4105CNA YD repeat protein BCAH820_1188 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BCAH820_1189 ENOG4107RN3 metallophosphoesterase BCAH820_1191 ENOG4107TVP HD domain protein BCAH820_1193 ENOG4108AEY RNA polymerase sigma factor BCAH820_1194 ENOG41086D8 Transcriptional regulator BCAH820_1198 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_1203 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCAH820_1208 ENOG4105ZU5 s-layer protein BCAH820_1209 ENOG4107QP3 malate synthase g BCAH820_1213 ENOG4105VEQ Cold shock protein BCAH820_1216 ENOG4105XVF Competence transcription factor BCAH820_1229 ENOG4105ERH Fumarylacetoacetate hydrolase BCAH820_1234 ENOG4105CAQ asparagine synthetase BCAH820_1235 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCAH820_1236 ENOG4105CH6 catalase BCAH820_1237 ENOG4105BZU Histidine kinase BCAH820_1241 ENOG4105QNR S1 RNA binding domain protein BCAH820_1243 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCAH820_1245 ENOG4107AYK membrAne BCAH820_1246 ENOG41073B9 BCAH820_1248 ENOG4108KP7 hydrolase BCAH820_1250 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BCAH820_1255 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCAH820_1256 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCAH820_1259 ENOG4105C31 Tryptophanyl-tRNA synthetase BCAH820_1262 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCAH820_1263 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCAH820_1265 ENOG4108JQ7 (ABC) transporter BCAH820_1266 ENOG4105UQX Mate efflux family protein BCAH820_1271 ENOG4108ZCF integral membrane protein BCAH820_1274 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCAH820_1276 ENOG4105DPN Oligoendopeptidase f BCAH820_1279 ENOG4108Z18 K06886 hemoglobin BCAH820_1280 ENOG4105MIX Adenylate cyclase BCAH820_1283 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BCAH820_1284 ENOG4105EMS pseudouridine synthase BCAH820_1288 ENOG4105K64 Glycosyl transferase, family 2 BCAH820_1292 ENOG4107TVC Glycosyl transferase, family 2 BCAH820_1296 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCAH820_1297 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCAH820_1299 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCAH820_1314 ENOG4105CK7 Sodium proline symporter BCAH820_1316 ENOG4105CRQ synthase (Component I) BCAH820_1317 ENOG4105DDQ anthranilate synthase BCAH820_1339 ENOG4105C7S Dehydrogenase BCAH820_1341 ENOG4105VZ8 Transcriptional regulator BCAH820_1360 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCAH820_1362 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BCAH820_1364 ENOG4105DZ1 carboxypeptidase BCAH820_1367 ENOG4105VFR signal peptidase BCAH820_1374 ENOG4105C26 Dehydrogenase BCAH820_1376 ENOG4105F38 ABC transporter, permease BCAH820_1377 ENOG4105D38 putrescine abc transporter BCAH820_1378 ENOG4107RUE extracellular solute-binding protein family 1 BCAH820_1380 ENOG4105EYF MMPL domain protein BCAH820_1382 ENOG4108YBP pseudouridine synthase BCAH820_1384 ENOG4105K4I Scp-like extracellular BCAH820_1385 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCAH820_1386 ENOG4105CQB FAD linked oxidase domain protein BCAH820_1389 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_1390 ENOG4105BZU Histidine kinase BCAH820_1391 ENOG4105JXH GntR family transcriptional regulator BCAH820_1395 ENOG4106A3R peptidase BCAH820_1397 ENOG4108QTI )-transporter BCAH820_1398 ENOG4107TS3 membrane protein, TerC BCAH820_1399 ENOG4105CZN Potassium uptake protein BCAH820_1400 ENOG410681C small acid-soluble spore protein BCAH820_1401 ENOG4108Z7G MaoC domain protein dehydratase BCAH820_1405 ENOG4105CHR reductase BCAH820_1407 ENOG4105MWK D-amino acid dehydrogenase, small subunit BCAH820_1411 ENOG4105C4Y ABC transporter BCAH820_1412 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCAH820_1413 ENOG4107RCV ABC transporter, permease BCAH820_1417 ENOG4105E98 transcriptional regulator DeoR family BCAH820_1420 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCAH820_1422 ENOG4105PXI polysaccharide deacetylase BCAH820_1424 ENOG4105BZU Histidine kinase BCAH820_1425 ENOG41090MY MarR family Transcriptional regulator BCAH820_1427 ENOG4106DF1 BCAH820_1429 ENOG4105BZU Histidine kinase BCAH820_1431 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCAH820_1432 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCAH820_1440 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCAH820_1441 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCAH820_1443 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCAH820_1444 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCAH820_1445 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCAH820_1446 ENOG4105CZV ABC transporter BCAH820_1448 ENOG4105CJ1 ABC, transporter BCAH820_1456 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCAH820_1457 ENOG4105EA8 2-Nitropropane dioxygenase BCAH820_1458 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCAH820_1460 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCAH820_1465 ENOG4105NQC Flavodoxin BCAH820_1472 ENOG4107QMU Mate efflux family protein BCAH820_1474 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BCAH820_1480 ENOG4105CZN Potassium uptake protein BCAH820_1481 ENOG41063Y9 BCAH820_1482 ENOG4105KBJ sporulation protein ytfj BCAH820_1487 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCAH820_1488 ENOG4105C7K acetolactate synthase BCAH820_1489 ENOG4108ZP8 Acetolactate synthase small subunit BCAH820_1504 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCAH820_1507 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCAH820_1508 ENOG4105E0M Sulfatase BCAH820_1510 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCAH820_1514 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCAH820_1515 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCAH820_1517 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCAH820_1518 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCAH820_1519 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCAH820_1520 ENOG4105C8J )-transporter BCAH820_1526 ENOG4105DFD Na H antiporter BCAH820_1530 ENOG4105ENE Histidine kinase BCAH820_1531 ENOG4105WH1 Two component transcriptional regulator luxr family BCAH820_1535 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCAH820_1545 ENOG4105CJ3 phosphate transporter BCAH820_1546 ENOG4107GRR phosphate transport regulator BCAH820_1547 ENOG4105BZ4 penicillin-binding protein BCAH820_1550 ENOG4105BZU Histidine kinase BCAH820_1551 ENOG4105I3N Conserved Protein BCAH820_1554 ENOG4105BZU Histidine kinase BCAH820_1561 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCAH820_1562 ENOG4105DZ1 carboxypeptidase BCAH820_1563 ENOG4108JIC nucleoside recognition domain protein BCAH820_1565 ENOG4105FE9 pseudouridine synthase BCAH820_1567 ENOG4107TWT Cytochrome c biogenesis protein BCAH820_1568 ENOG4105CRE cytochrome C BCAH820_1569 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_1570 ENOG4105BZU Histidine kinase BCAH820_1571 ENOG4108WBT adenosyltransferase BCAH820_1572 ENOG41063SB peptidase BCAH820_1576 ENOG4108SAX Membrane BCAH820_1579 ENOG4105C9U ATP-dependent DNA helicase RecQ BCAH820_1580 ENOG4105I7S Abortive infection protein BCAH820_1582 ENOG4107RGJ metallophosphoesterase BCAH820_1583 ENOG4107X2D transcriptional regulator, merr family BCAH820_1584 ENOG4108S6Z Negative regulator of genetic competence BCAH820_1589 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCAH820_1590 ENOG4107RB3 L-asparaginase BCAH820_1596 ENOG4105S2F BCAH820_1597 ENOG41065D1 BCAH820_1603 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCAH820_1606 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCAH820_1608 ENOG4105EAH synthase BCAH820_1612 ENOG4105CIH Imidazole acetol-phosphate transaminase BCAH820_1613 ENOG41068YB TPR repeat-containing protein BCAH820_1616 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCAH820_1617 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCAH820_1618 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BCAH820_1624 ENOG4108JYZ YitT family BCAH820_1625 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCAH820_1628 ENOG4105FJR Lmbe family BCAH820_1629 ENOG4105CPK Glycosyl transferase (Group 1 BCAH820_1636 ENOG4105DVT helicase BCAH820_1637 ENOG4105YAC BCAH820_1641 ENOG4105CSM endonuclease III BCAH820_1643 ENOG4105BZ4 penicillin-binding protein BCAH820_1654 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCAH820_1656 ENOG4105DVT helicase BCAH820_1657 ENOG4105CTD carboxy-peptidase BCAH820_1660 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCAH820_1662 ENOG4105C2W permease BCAH820_1663 ENOG4105DHF Membrane BCAH820_1665 ENOG410890F Dynamin family BCAH820_1667 ENOG4108W0I acetyltransferase BCAH820_1669 ENOG4105KHC sulfurtransferase BCAH820_1672 ENOG4106032 Glutathionylspermidine synthase BCAH820_1684 ENOG4105CPK Glycosyl transferase (Group 1 BCAH820_1687 ENOG4108SZE gCN5-related N-acetyltransferase BCAH820_1691 ENOG41081VK Ribonuclease BCAH820_1704 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCAH820_1706 ENOG4107RWR Sodium hydrogen exchanger BCAH820_1707 ENOG4105CN5 Metallo-Beta-Lactamase BCAH820_1708 ENOG4108Z5V transcriptional regulator, merr family BCAH820_1710 ENOG4105H67 Protein of unknown function (DUF421) BCAH820_1711 ENOG41080C8 DUF218 domain BCAH820_1723 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCAH820_1725 ENOG4107R0U MotA TolQ exbB proton channel BCAH820_1726 ENOG4105ER2 Ompa motb domain protein BCAH820_1727 ENOG4107YTP response regulator receiver protein BCAH820_1728 ENOG4105CBS Chea signal transduction histidine kinase BCAH820_1729 ENOG4105DD5 Flagellar motor switch protein BCAH820_1732 ENOG4105BZU Histidine kinase BCAH820_1736 ENOG4105E1Q flagellar hook-associated protein BCAH820_1737 ENOG4105DTJ flagellar hook-associated protein BCAH820_1738 ENOG4105DTS flagellar hook-associated BCAH820_1741 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCAH820_1742 ENOG4108ZC9 flagellar basal-body rod protein flgc BCAH820_1743 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCAH820_1744 ENOG4107U2N Flagellar M-ring protein BCAH820_1745 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCAH820_1751 ENOG4105BZE flagellar hook protein, FlgE BCAH820_1754 ENOG4107R88 Chemotaxis protein (CheV) BCAH820_1756 ENOG4105I03 Flagellin BCAH820_1757 ENOG4105I03 Flagellin BCAH820_1758 ENOG4105E4C Lytic transglycosylase catalytic BCAH820_1760 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCAH820_1761 ENOG4105DD5 Flagellar motor switch protein BCAH820_1763 ENOG4105CN7 Flagellar biosynthetic protein FliP BCAH820_1764 ENOG4105VS8 Flagellar biosynthetic protein fliq BCAH820_1766 ENOG4105D00 flagellar biosynthetic protein flhB BCAH820_1767 ENOG4105D7B Flagellar biosynthesis protein flha BCAH820_1768 ENOG4105FZW flagellar biosynthesis regulator FlhF BCAH820_1769 ENOG4105KTQ flagellar basal-body rod protein BCAH820_1770 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCAH820_1775 ENOG4108RZE Tetr family transcriptional regulator BCAH820_1779 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCAH820_1784 ENOG4108KB2 LysR family Transcriptional regulator BCAH820_1785 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCAH820_1786 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCAH820_1787 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCAH820_1788 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BCAH820_1795 ENOG4105CVJ phosphoglycerate mutase BCAH820_1799 ENOG4105K56 Transcriptional regulator BCAH820_1801 ENOG4105CAQ asparagine synthetase BCAH820_1802 ENOG4105CAQ asparagine synthetase BCAH820_1806 ENOG4105PGM cation diffusion facilitator family transporter BCAH820_1808 ENOG4105DRR Transcriptional regulator, GntR family BCAH820_1809 ENOG4108UZ3 Transporter BCAH820_1810 ENOG4105CKI cobalamin synthesis protein BCAH820_1812 ENOG4108PJD permease BCAH820_1816 ENOG4105DFD Na H antiporter BCAH820_1817 ENOG4105VUF Transcriptional regulator BCAH820_1819 ENOG4105C9Q fumarate hydratase class II BCAH820_1823 ENOG4107QJQ Mate efflux family protein BCAH820_1824 ENOG4105EC3 peptidase S51, dipeptidase E BCAH820_1828 ENOG4107QIV Cytochrome c biogenesis protein BCAH820_1834 ENOG4106BRA Membrane BCAH820_1841 ENOG4105CJ1 ABC, transporter BCAH820_1845 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCAH820_1847 ENOG4108IJ0 Aspartate ammonia-lyase BCAH820_1848 ENOG4105C6K Malic enzyme BCAH820_1860 ENOG4105FVX BCAH820_1868 ENOG4105CSR polyphosphate kinase 2 BCAH820_1869 ENOG4105DXI Major Facilitator superfamily BCAH820_1872 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCAH820_1874 ENOG4105EU0 Major facilitator Superfamily BCAH820_1875 ENOG4105C6T cysteine synthase BCAH820_1879 ENOG4105C8J )-transporter BCAH820_1881 ENOG4105X5K response regulator receiver protein BCAH820_1882 ENOG4105H67 Protein of unknown function (DUF421) BCAH820_1885 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCAH820_1886 ENOG4105CHR reductase BCAH820_1887 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCAH820_1888 ENOG4105C7K acetolactate synthase BCAH820_1889 ENOG4108ZP8 Acetolactate synthase small subunit BCAH820_1890 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BCAH820_1892 ENOG4105C7B Threonine dehydratase BCAH820_1896 ENOG4105C6X Major Facilitator BCAH820_1897 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCAH820_1899 ENOG4105DY9 regulatoR BCAH820_1900 ENOG4105CYC Transferase BCAH820_1904 ENOG4105F6J Alpha beta hydrolase fold BCAH820_1911 ENOG41068WN BCAH820_1915 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCAH820_1916 ENOG4105C72 UPF0176 protein BCAH820_1918 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCAH820_1921 ENOG4105C0X amino acid BCAH820_1926 ENOG4107RHR regulatoR BCAH820_1928 ENOG4105D9N nucleoside BCAH820_1929 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCAH820_1936 ENOG4107RAQ aminopeptidase BCAH820_1937 ENOG4107R16 Multicopper oxidase BCAH820_1949 ENOG4108T5E Copper resistance protein BCAH820_1950 ENOG4105KTB nuclear export factor GLE1 BCAH820_1951 ENOG4107RT3 EamA-like transporter family BCAH820_1952 ENOG4105GZI Transcriptional regulator BCAH820_1953 ENOG4108Z40 Transcriptional regulator BCAH820_1954 ENOG4107ZXU DSBA oxidoreductase BCAH820_1955 ENOG4108TVJ Nitroreductase BCAH820_1957 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCAH820_1958 ENOG4106F5Q Membrane BCAH820_1959 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCAH820_1961 ENOG4105CKI cobalamin synthesis protein BCAH820_1965 ENOG4108Z7G MaoC domain protein dehydratase BCAH820_1966 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCAH820_1968 ENOG4105C0Z ABC transporter BCAH820_1969 ENOG4108IV0 ABC, transporter BCAH820_1970 ENOG4105C32 Amino acid ABC transporter (Permease) BCAH820_1972 ENOG4105SKE transcriptional Regulator LysR family BCAH820_1978 ENOG4105C4M (Ubiquinol oxidase) subunit I BCAH820_1979 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCAH820_1980 ENOG4108JJ9 ABC, transporter BCAH820_1981 ENOG4108JJ8 (ABC) transporter BCAH820_1984 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCAH820_1990 ENOG4105BZ1 (ABC) transporter BCAH820_1991 ENOG4105EFI regulatoR BCAH820_1993 ENOG4105BZU Histidine kinase BCAH820_1997 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCAH820_1998 ENOG4108ZJ4 polysaccharide deacetylase BCAH820_1999 ENOG4106AKJ BCAH820_2002 ENOG4105D6E homoserine dehydrogenase BCAH820_2008 ENOG4108KGH TRANSCRIPTIONal BCAH820_2010 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_2011 ENOG4105BZU Histidine kinase BCAH820_2012 ENOG4107VMI polysaccharide deacetylase BCAH820_2014 ENOG4105KT7 mgtC SapB transporter BCAH820_2015 ENOG4105VRR gCN5-related N-acetyltransferase BCAH820_2017 ENOG4105DUU IucA IucC family protein BCAH820_2018 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_2021 ENOG4108WBH protein TIM barrel BCAH820_2022 ENOG4105YWU small acid-soluble spore protein BCAH820_2024 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCAH820_2034 ENOG4105KRN Transcriptional regulator, abrb family BCAH820_2036 ENOG4105YVS arsR family transcriptional regulator BCAH820_2037 ENOG4107SET aldo keto reductase BCAH820_2038 ENOG4107XZQ multidrug resistance protein BCAH820_2043 ENOG4105C8Q Methyl-accepting chemotaxis BCAH820_2046 ENOG4108K88 Membrane BCAH820_2047 ENOG4108WPJ Ferritin-like domain BCAH820_2051 ENOG4105DEN Luciferase family BCAH820_2055 ENOG4107QM2 Aldo Keto reductase BCAH820_2056 ENOG4105CKI cobalamin synthesis protein BCAH820_2066 ENOG4105DSE periplasmic solute binding protein BCAH820_2069 ENOG4105K4T epimerase BCAH820_2071 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCAH820_2080 ENOG4107T5V SNARE associated Golgi BCAH820_2084 ENOG4108PJD permease BCAH820_2086 ENOG4108S4H thioesterase Superfamily protein BCAH820_2087 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCAH820_2091 ENOG4105SXS Protein of unknown function (DUF456) BCAH820_2092 ENOG4105C37 (CBS) domain BCAH820_2096 ENOG4108Z7R Chaperone CsaA BCAH820_2099 ENOG4108ZRV stage ii sporulation protein p BCAH820_2101 ENOG4108VXD carboxy-peptidase BCAH820_2103 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCAH820_2108 ENOG4108X4Q Hydrolase BCAH820_2110 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCAH820_2111 ENOG4107RBS Methyltransferase BCAH820_2114 ENOG41087PP glycosyltransferase MGT family BCAH820_2115 ENOG4108JYZ YitT family BCAH820_2116 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCAH820_2122 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCAH820_2135 ENOG4105KBJ sporulation protein ytfj BCAH820_2140 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCAH820_2144 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BCAH820_2145 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCAH820_2147 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCAH820_2148 ENOG4105EMN RNA polymerase sigma factor BCAH820_2150 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BCAH820_2152 ENOG4105CNW domain protein BCAH820_2154 ENOG4108V06 Glutathione peroxidase BCAH820_2157 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCAH820_2159 ENOG4108IUE nitrate reductase beta subunit BCAH820_2160 ENOG4105R3A Nitrate reductase BCAH820_2163 ENOG4105CZV ABC transporter BCAH820_2165 ENOG4107V6Q Cyclic nucleotide-binding domain BCAH820_2166 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCAH820_2167 ENOG4105D06 uba thif-type nad fad binding protein BCAH820_2168 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCAH820_2169 ENOG4108ZAF Molybdopterin BCAH820_2173 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCAH820_2174 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCAH820_2175 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCAH820_2176 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BCAH820_2177 ENOG4108IFG nitrite reductase, (NAD(P)H) BCAH820_2178 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BCAH820_2185 ENOG4105MCT stage V sporulation protein S BCAH820_2190 ENOG4105C5H ABC transporter BCAH820_2193 ENOG4108UUM single-stranded DNA-binding protein BCAH820_2197 ENOG4107YX5 Pfam:DUF548 BCAH820_2204 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCAH820_2205 ENOG4105C5S asparaginyl-tRNA synthetase BCAH820_2209 ENOG4105EC2 ftsk spoIIIe BCAH820_2220 ENOG4106BHF BCAH820_2221 ENOG4106ANW SMI1_KNR4 BCAH820_2238 ENOG4105BZW Glycerate kinase BCAH820_2239 ENOG4107QPK )-transporter BCAH820_2240 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_2241 ENOG41062D9 Histidine kinase BCAH820_2244 ENOG4105C8J )-transporter BCAH820_2248 ENOG4107XGZ Hydrolase BCAH820_2249 ENOG4105CY2 Citrate transporter BCAH820_2250 ENOG4105C0A alcohol dehydrogenase BCAH820_2253 ENOG4105KD7 acetyltransferase BCAH820_2254 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCAH820_2259 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCAH820_2262 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCAH820_2265 ENOG4107RVG penicillin-binding protein BCAH820_2267 ENOG4105E9Q Acyl-transferase BCAH820_2268 ENOG4108UT2 hemolysin iii BCAH820_2270 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCAH820_2272 ENOG4108RCR degv family BCAH820_2273 ENOG4107T8T UPF0173 metal-dependent hydrolase BCAH820_2274 ENOG4108KF3 Electron transport protein SCO1 SenC BCAH820_2275 ENOG4107Y70 Heat shock protein BCAH820_2276 ENOG4105CAQ asparagine synthetase BCAH820_2280 ENOG4108MES Periplasmic binding protein BCAH820_2281 ENOG4105F0I Aminotransferase BCAH820_2287 ENOG4107Y70 Heat shock protein BCAH820_2288 ENOG4105D8X mechanosensitive ion channel BCAH820_2289 ENOG4105BZU Histidine kinase BCAH820_2290 ENOG4105WH1 Two component transcriptional regulator luxr family BCAH820_2292 ENOG4106KNT transcriptional regulator BCAH820_2298 ENOG4105CMG Carbohydrate kinase BCAH820_2299 ENOG4105CMG Carbohydrate kinase BCAH820_2305 ENOG4108IJ8 ABC transporter BCAH820_2306 ENOG4105E90 ABC transporter BCAH820_2313 ENOG4105C37 (CBS) domain BCAH820_2319 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCAH820_2322 ENOG4107S4Y M20 DapE family protein YgeY BCAH820_2323 ENOG4108TSC N-acetyltransferase BCAH820_2324 ENOG4108JUB Transcriptional regulator BCAH820_2325 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCAH820_2333 ENOG4108N23 SpoOM-related protein BCAH820_2335 ENOG410841Q phosphoesterase PA-phosphatase related protein BCAH820_2336 ENOG4105SZ6 Thioredoxin BCAH820_2339 ENOG4108IBT Inherit from COG: transposase BCAH820_2357 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCAH820_2364 ENOG4105BZ4 penicillin-binding protein BCAH820_2365 ENOG4105CZM Major Facilitator BCAH820_2366 ENOG4105W8X HesB YadR YfhF-family protein BCAH820_2368 ENOG4105DXD 2-methylcitrate dehydratase BCAH820_2369 ENOG4105CR4 methylisocitrate lyase BCAH820_2371 ENOG4105C1G acyl-Coa dehydrogenase BCAH820_2372 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCAH820_2374 ENOG4105N14 lysine exporter protein LysE YggA BCAH820_2375 ENOG4105E39 Enoyl-CoA hydratase BCAH820_2378 ENOG4107RFY SbcCD D subunit BCAH820_2379 ENOG4105EYH Exonuclease BCAH820_2385 ENOG4105FCD Major Facilitator BCAH820_2386 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCAH820_2387 ENOG4105E4F Isochorismate synthase BCAH820_2388 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCAH820_2389 ENOG4105WQI isochorismatase BCAH820_2390 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_2391 ENOG4105WQT MbtH domain protein BCAH820_2392 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_2395 ENOG4105K70 DNA-binding protein BCAH820_2399 ENOG4105BZG amino acid carrier protein BCAH820_2403 ENOG4105FE9 pseudouridine synthase BCAH820_2405 ENOG4105C22 threonyL-tRNA synthetase BCAH820_2406 ENOG4105C19 ABC transporter BCAH820_2409 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCAH820_2413 ENOG4108D32 Methyltransferase BCAH820_2417 ENOG41081I9 integral membrane protein BCAH820_2419 ENOG4108Y4K DNA-binding transcriptional activator BCAH820_2422 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCAH820_2424 ENOG4105EYF MMPL domain protein BCAH820_2430 ENOG4105WCN acetyltransferase BCAH820_2436 ENOG4105C1Q protoporphyrinogen oxidase BCAH820_2438 ENOG41068WN BCAH820_2440 ENOG4105VEQ Cold shock protein BCAH820_2444 ENOG410667J hydrolase BCAH820_2451 ENOG4107V2S Transcriptional regulator BCAH820_2452 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCAH820_2455 ENOG4105DND Transcriptional regulator BCAH820_2456 ENOG4108RPX mosc domain containing protein BCAH820_2459 ENOG4105BZ1 (ABC) transporter BCAH820_2460 ENOG4105BZ1 (ABC) transporter BCAH820_2463 ENOG4108JCI Transcriptional regulator BCAH820_2469 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCAH820_2472 ENOG4108KPJ rna polymerase sigma factor BCAH820_2477 ENOG4105F32 YngK protein BCAH820_2483 ENOG4105RD7 BadF BadG BcrA BcrD BCAH820_2485 ENOG4107STF Involved in phosphonate degradation (By similarity) BCAH820_2493 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCAH820_2496 ENOG4105C1J atp-dependent rna helicase BCAH820_2500 ENOG4108RZE Tetr family transcriptional regulator BCAH820_2504 ENOG41088CC tellurite resistance protein tehB BCAH820_2506 ENOG4108I0C methyltransferase BCAH820_2507 ENOG4107RA9 decarboxylase BCAH820_2508 ENOG41090HR transcriptional regulator BCAH820_2514 ENOG4105CIN aminoacyl-histidine dipeptidase BCAH820_2519 ENOG4107RF6 penicillin-binding protein BCAH820_2521 ENOG4107RF6 penicillin-binding protein BCAH820_2523 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCAH820_2524 ENOG4105ETE Transcriptional regulator (LacI family BCAH820_2525 ENOG4105IE8 Alpha-ketoglutarate permease BCAH820_2526 ENOG4105CK5 oxidoreductase BCAH820_2532 ENOG4105D2N Aldolase BCAH820_2533 ENOG4105DH8 myo-inositol catabolism BCAH820_2536 ENOG4105CGH 5'-nucleotidase BCAH820_2539 ENOG4105VZ8 Transcriptional regulator BCAH820_2541 ENOG4108VXD carboxy-peptidase BCAH820_2544 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BCAH820_2545 ENOG41067SE Tetr family transcriptional regulator BCAH820_2546 ENOG4105C5H ABC transporter BCAH820_2548 ENOG4105BZU Histidine kinase BCAH820_2552 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BCAH820_2555 ENOG4105CJ1 ABC, transporter BCAH820_2557 ENOG4107Z3H Transcriptional regulator, TetR family BCAH820_2560 ENOG4105C1G acyl-Coa dehydrogenase BCAH820_2561 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCAH820_2562 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCAH820_2563 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCAH820_2564 ENOG4105E39 Enoyl-CoA hydratase BCAH820_2565 ENOG4107QX3 carboxylase BCAH820_2566 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCAH820_2568 ENOG4105WCN acetyltransferase BCAH820_2569 ENOG4105DBI uridine monophosphokinase BCAH820_2572 ENOG4105DZ1 carboxypeptidase BCAH820_2575 ENOG4105T9C HD domain BCAH820_2577 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCAH820_2587 ENOG4105FQP Beta-lactamase BCAH820_2591 ENOG41089UC methyltransferase, type 11 BCAH820_2594 ENOG4105CUV Homoserine Kinase BCAH820_2606 ENOG4105CPQ Dehydrogenase BCAH820_2609 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCAH820_2628 ENOG4105ETU transcriptional activator (TenA BCAH820_2652 ENOG410667J hydrolase BCAH820_2653 ENOG4105BZU Histidine kinase BCAH820_2654 ENOG4107RF6 penicillin-binding protein BCAH820_2661 ENOG4108HGU Histidine kinase BCAH820_2664 ENOG4105CB2 alcohol dehydrogenase BCAH820_2665 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCAH820_2666 ENOG4105CJN penicillin-binding protein BCAH820_2668 ENOG4105FQP Beta-lactamase BCAH820_2674 ENOG4108V4B ThiJ pfpI BCAH820_2679 ENOG4107Y80 Major Facilitator superfamily BCAH820_2682 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCAH820_2686 ENOG4107Y9U Membrane BCAH820_2695 ENOG4105FCD Major Facilitator BCAH820_2698 ENOG4105E09 nadh pyrophosphatase BCAH820_2699 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCAH820_2700 ENOG4108Z4K mutator MutT protein BCAH820_2707 ENOG4108XI2 Domain of unknown function (DUF1963) BCAH820_2711 ENOG4108NRW Phospholipase, patatin family BCAH820_2712 ENOG4105KWG Pfam:DUF1696 BCAH820_2719 ENOG4105PKS Excinuclease abc c subunit domain protein BCAH820_2728 ENOG4107VFR oxidoreductase BCAH820_2734 ENOG4105DY8 decarboxylase BCAH820_2737 ENOG4108IUM Glycogen debranching enzyme BCAH820_2742 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCAH820_2744 ENOG4105FDR Membrane BCAH820_2755 ENOG4105MSI germination protein ypeb BCAH820_2762 ENOG4107Z3H Transcriptional regulator, TetR family BCAH820_2768 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCAH820_2772 ENOG4105E98 transcriptional regulator DeoR family BCAH820_2777 ENOG4107QKR Dehydrogenase BCAH820_2778 ENOG4107QKR Dehydrogenase BCAH820_2780 ENOG4107RUY (E1 component), alpha subunit BCAH820_2783 ENOG4105E1F short-chain dehydrogenase reductase BCAH820_2784 ENOG4105RHY Pfam:UPF0157 BCAH820_2792 ENOG4107SQ8 Glycine betaine BCAH820_2793 ENOG4108IJ7 Glycine betaine BCAH820_2798 ENOG4105E66 phosphoriboisomerase A BCAH820_2799 ENOG41082BV acetyltransferase BCAH820_2800 ENOG4108M1A Chitin-binding protein BCAH820_2801 ENOG41087PP glycosyltransferase MGT family BCAH820_2806 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCAH820_2811 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCAH820_2817 ENOG4108Z7F N-acetyltransferase BCAH820_2821 ENOG4105EEM helicase BCAH820_2825 ENOG4105C9U ATP-dependent DNA helicase RecQ BCAH820_2833 ENOG4108M1A Chitin-binding protein BCAH820_2836 ENOG4105BZG amino acid carrier protein BCAH820_2837 ENOG4105C26 Dehydrogenase BCAH820_2838 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCAH820_2839 ENOG4105CTU Proline racemase BCAH820_2840 ENOG4105CTU Proline racemase BCAH820_2841 ENOG41080HI glycine oxidase BCAH820_2843 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCAH820_2849 ENOG4107T5V SNARE associated Golgi BCAH820_2852 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCAH820_2853 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BCAH820_2856 ENOG4105DTQ mandelate racemase muconate lactonizing BCAH820_2865 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCAH820_2866 ENOG4105BZU Histidine kinase BCAH820_2867 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_2871 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BCAH820_2874 ENOG4105DPN Oligoendopeptidase f BCAH820_2876 ENOG4105EPR degv family BCAH820_2884 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCAH820_2885 ENOG4106K7D Major facilitator family transporter BCAH820_2890 ENOG4107BMA Transglycosylase associated protein BCAH820_2893 ENOG41089UC methyltransferase, type 11 BCAH820_2901 ENOG4105CHM Aminotransferase BCAH820_2904 ENOG4108ZMI UPF0477 protein BCAH820_2907 ENOG4105DVE abc transporter atp-binding protein BCAH820_2916 ENOG4105C02 permease BCAH820_2918 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCAH820_2919 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCAH820_2920 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCAH820_2925 ENOG4105E09 nadh pyrophosphatase BCAH820_2929 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCAH820_2940 ENOG4107VC0 DNA alkylation repair enzyme BCAH820_2943 ENOG4107VMI polysaccharide deacetylase BCAH820_2945 ENOG4108ZCF integral membrane protein BCAH820_2946 ENOG4105E0M Sulfatase BCAH820_2947 ENOG4105C5H ABC transporter BCAH820_2949 ENOG4105EYF MMPL domain protein BCAH820_2951 ENOG41082JN Transcriptional regulator BCAH820_2955 ENOG4105CIH Imidazole acetol-phosphate transaminase BCAH820_2957 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCAH820_2964 ENOG41069ER domain protein BCAH820_2966 ENOG4105EMN RNA polymerase sigma factor BCAH820_2971 ENOG4105D4B ABC, transporter BCAH820_2973 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCAH820_2976 ENOG4105DKT Transcriptional regulator BCAH820_2977 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BCAH820_2979 ENOG41061GT Aldolase BCAH820_2983 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCAH820_2989 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BCAH820_2991 ENOG4105II7 pyrroline-5-carboxylate reductase BCAH820_2995 ENOG4107258 Transcriptional regulator BCAH820_2997 ENOG4105E0Y RtcB Protein BCAH820_2998 ENOG4105ECK Fatty Acid Desaturase BCAH820_2999 ENOG4105G6Z alkaline phosphatase BCAH820_3001 ENOG4105VMP Transcriptional regulator BCAH820_3004 ENOG41090T1 Membrane BCAH820_3006 ENOG4108WCX response regulator BCAH820_3008 ENOG41068WN BCAH820_3014 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCAH820_3018 ENOG4105CKK Glycosyl transferase, family 2 BCAH820_3021 ENOG4105CKK Glycosyl transferase, family 2 BCAH820_3023 ENOG4105C8Y Acetylornithine aminotransferase BCAH820_3031 ENOG4108TVJ Nitroreductase BCAH820_3032 ENOG4105FS7 Transcriptional regulator BCAH820_3036 ENOG4105ERH Fumarylacetoacetate hydrolase BCAH820_3040 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_3041 ENOG4105CHU acetyl-coa acetyltransferase BCAH820_3042 ENOG4105E39 Enoyl-CoA hydratase BCAH820_3043 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCAH820_3044 ENOG4105CS2 ec 3.2.1.21 BCAH820_3045 ENOG4105VCP PTS System BCAH820_3046 ENOG4108QVC Component IIC BCAH820_3049 ENOG4105VZJ PTS System BCAH820_3051 ENOG4105G9B Transcriptional regulator BCAH820_3052 ENOG4105D2S major facilitator superfamily BCAH820_3053 ENOG4105EFZ amidohydrolase BCAH820_3062 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCAH820_3064 ENOG4105C19 ABC transporter BCAH820_3070 ENOG4108XET gCN5-related N-acetyltransferase BCAH820_3083 ENOG410635A Membrane BCAH820_3085 ENOG4108IQI permease BCAH820_3087 ENOG4105F1N DNA alkylation repair BCAH820_3093 ENOG4107RF6 penicillin-binding protein BCAH820_3095 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BCAH820_3102 ENOG4105P4J Allophanate hydrolase, subunit 1 BCAH820_3103 ENOG4107258 Transcriptional regulator BCAH820_3105 ENOG4106N3A copper homeostasis protein cutc BCAH820_3106 ENOG4108ZRV stage ii sporulation protein p BCAH820_3107 ENOG4108ZHR arsR family transcriptional regulator BCAH820_3109 ENOG4105FDT acyl-CoA dehydrogenase BCAH820_3113 ENOG4105DWD nucleoside recognition domain protein BCAH820_3119 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCAH820_3133 ENOG4105E2A Dehydrogenase BCAH820_3135 ENOG4108IJ0 Aspartate ammonia-lyase BCAH820_3136 ENOG4105HDK L-asparaginase BCAH820_3137 ENOG4108IMY Transcriptional regulator BCAH820_3141 ENOG4108B31 Spore germination protein BCAH820_3143 ENOG4105BZU Histidine kinase BCAH820_3148 ENOG41075H3 AraC family transcriptional regulator BCAH820_3150 ENOG4105YWU small acid-soluble spore protein BCAH820_3151 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCAH820_3152 ENOG4105CUB amino acid BCAH820_3154 ENOG4105II7 pyrroline-5-carboxylate reductase BCAH820_3158 ENOG4108NHD germination protein BCAH820_3159 ENOG4108Q8B Spore germination protein BCAH820_3164 ENOG4105CSV Glutaminase BCAH820_3171 ENOG4105CGH 5'-nucleotidase BCAH820_3172 ENOG4105CH6 catalase BCAH820_3174 ENOG4105CHJ isochorismatase hydrolase BCAH820_3175 ENOG4105CHJ isochorismatase hydrolase BCAH820_3179 ENOG41090MY MarR family Transcriptional regulator BCAH820_3186 ENOG4108606 TspO/MBR family BCAH820_3187 ENOG4105CVP deoxyribo-dipyrimidine photolyase BCAH820_3190 ENOG4108TWJ NADH dehydrogenase subunit 5 BCAH820_3191 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCAH820_3193 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCAH820_3194 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BCAH820_3200 ENOG4105DBI uridine monophosphokinase BCAH820_3202 ENOG4105D6J arsenicaL-resistance protein BCAH820_3203 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCAH820_3204 ENOG41085FC arsR family transcriptional regulator BCAH820_3208 ENOG4105BZU Histidine kinase BCAH820_3209 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_3211 ENOG4107P5I polyketide synthase BCAH820_3212 ENOG4108IG5 Transcriptional regulator BCAH820_3213 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BCAH820_3214 ENOG4108YXU transcriptional regulator AsnC family BCAH820_3229 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCAH820_3230 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_3232 ENOG4105IIP Membrane BCAH820_3235 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_3236 ENOG41062D9 Histidine kinase BCAH820_3241 ENOG4105K6H D-cysteine desulfhydrase BCAH820_3246 ENOG4108NNI Beta-lactamase domain-containing protein BCAH820_3247 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BCAH820_3249 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCAH820_3250 ENOG4105JQZ Methyltransferase BCAH820_3253 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BCAH820_3254 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCAH820_3257 ENOG4105BZU Histidine kinase BCAH820_3259 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCAH820_3261 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BCAH820_3262 ENOG4107QR9 Iron-sulfur cluster binding protein BCAH820_3264 ENOG4106P55 Transcriptional regulator BCAH820_3266 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCAH820_3272 ENOG4105TRI Hydrolase BCAH820_3279 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCAH820_3286 ENOG4105C44 Serine transporter BCAH820_3287 ENOG4105EJQ L-serine dehydratase BCAH820_3290 ENOG4108JPW Aminotransferase BCAH820_3293 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BCAH820_3295 ENOG4105DVH amino acid BCAH820_3298 ENOG4108JQ1 Dehydrogenase BCAH820_3302 ENOG4108AEY RNA polymerase sigma factor BCAH820_3305 ENOG41082W1 Cupin 2, conserved barrel domain protein BCAH820_3306 ENOG410874W AraC family transcriptional regulator BCAH820_3311 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCAH820_3319 ENOG4108ISG Major Facilitator BCAH820_3321 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCAH820_3322 ENOG4105CZM Major Facilitator BCAH820_3324 ENOG4105RXJ BCAH820_3325 ENOG4105KPY Small multidrug resistance protein BCAH820_3326 ENOG4105KBX Transcriptional regulator, TetR family BCAH820_3329 ENOG4105CRW Short chain fatty acid transporter BCAH820_3331 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCAH820_3337 ENOG4108JJB ABC transporter BCAH820_3338 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCAH820_3344 ENOG4105EQ0 Major Facilitator superfamily BCAH820_3345 ENOG4108IND Tetr family transcriptional regulator BCAH820_3348 ENOG4105K59 histidine triad (HIT) protein BCAH820_3349 ENOG4108Z4K mutator MutT protein BCAH820_3350 ENOG4108Z66 YbaK ebsC protein BCAH820_3354 ENOG4105KVH Transcriptional regulator BCAH820_3355 ENOG4108RCM Nitroreductase BCAH820_3360 ENOG4108PSK reductase BCAH820_3362 ENOG4105CJ1 ABC, transporter BCAH820_3374 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCAH820_3375 ENOG4105DKQ ROK family BCAH820_3376 ENOG4106UW1 Major Facilitator superfamily BCAH820_3377 ENOG4108UW5 maltose o-acetyltransferase BCAH820_3378 ENOG4105C31 Tryptophanyl-tRNA synthetase BCAH820_3384 ENOG4105DMQ Methyltransferase BCAH820_3386 ENOG4105EV4 Multidrug resistance protein mdtH BCAH820_3391 ENOG4105C37 (CBS) domain BCAH820_3394 ENOG4105DDN Pentapeptide repeat-containing protein BCAH820_3395 ENOG4105XDF Protein of unknown function (DUF1272) BCAH820_3396 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCAH820_3397 ENOG4105CMG Carbohydrate kinase BCAH820_3398 ENOG4105C6Z Gluconate BCAH820_3399 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCAH820_3402 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCAH820_3405 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BCAH820_3407 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BCAH820_3408 ENOG4105D4Y metalloprotease BCAH820_3415 ENOG4105C44 Serine transporter BCAH820_3424 ENOG4108TZY GntR Family Transcriptional Regulator BCAH820_3425 ENOG4105D9R oxidoreductase BCAH820_3426 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCAH820_3427 ENOG4105KVH Transcriptional regulator BCAH820_3428 ENOG4105KVH Transcriptional regulator BCAH820_3435 ENOG4105JAB phenazine biosynthesis protein, phzf family BCAH820_3437 ENOG4105CHR reductase BCAH820_3440 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCAH820_3441 ENOG4105KVH Transcriptional regulator BCAH820_3443 ENOG4108ZJ4 polysaccharide deacetylase BCAH820_3458 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCAH820_3468 ENOG4105H3G oxidoreductase BCAH820_3476 ENOG4105CIS alcohol dehydrogenase BCAH820_3484 ENOG4108TN2 lmbE family BCAH820_3486 ENOG4107R3E Citrate transporter BCAH820_3489 ENOG4108MES Periplasmic binding protein BCAH820_3490 ENOG4105EHG Permease protein BCAH820_3491 ENOG4105DQ5 transport system permease protein BCAH820_3492 ENOG4105NX3 Membrane BCAH820_3493 ENOG4107ZY0 Phenazine biosynthesis-like protein BCAH820_3498 ENOG4107CUJ Protein of unknown function (DUF2690) BCAH820_3500 ENOG4107V2S Transcriptional regulator BCAH820_3504 ENOG4105C98 muts2 protein BCAH820_3508 ENOG4105E5K Alpha-amylase BCAH820_3509 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCAH820_3510 ENOG4105DPN Oligoendopeptidase f BCAH820_3511 ENOG4108A04 Beta-lactamase BCAH820_3517 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCAH820_3521 ENOG41082BM Transcriptional regulator, arsr family BCAH820_3522 ENOG4105CIS alcohol dehydrogenase BCAH820_3529 ENOG4105C09 Bile acid BCAH820_3530 ENOG4105CQB FAD linked oxidase domain protein BCAH820_3534 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCAH820_3536 ENOG4105K64 Glycosyl transferase, family 2 BCAH820_3537 ENOG4105E39 Enoyl-CoA hydratase BCAH820_3539 ENOG4105KT7 mgtC SapB transporter BCAH820_3541 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCAH820_3542 ENOG41073R8 VanW family BCAH820_3544 ENOG4108R1P BCAH820_3548 ENOG4105VEQ Cold shock protein BCAH820_3552 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCAH820_3555 ENOG410904N short-chain dehydrogenase reductase BCAH820_3557 ENOG4106IQC argininosuccinate lyase BCAH820_3560 ENOG4108IA2 Sodium pantothenate symporter BCAH820_3562 ENOG4105C26 Dehydrogenase BCAH820_3563 ENOG4105CHR reductase BCAH820_3565 ENOG4105EWU Squalene--hopene cyclase BCAH820_3567 ENOG4105FR1 rard protein BCAH820_3568 ENOG410696E Membrane BCAH820_3571 ENOG4105D1F ATP-binding protein BCAH820_3573 ENOG4108ZAF Molybdopterin BCAH820_3574 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCAH820_3575 ENOG4105D06 uba thif-type nad fad binding protein BCAH820_3576 ENOG4105TMB Formate nitrite transporter BCAH820_3578 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCAH820_3579 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCAH820_3581 ENOG4108JB9 formate dehydrogenase BCAH820_3582 ENOG4105E1K spore germination protein BCAH820_3594 ENOG4105DQ6 Transposase BCAH820_3597 ENOG4107QJT sodium dicarboxylate symporter BCAH820_3598 ENOG4108KGH TRANSCRIPTIONal BCAH820_3600 ENOG4105EMN RNA polymerase sigma factor BCAH820_3604 ENOG4105CIG ABC transporter BCAH820_3606 ENOG4105D9R oxidoreductase BCAH820_3608 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCAH820_3610 ENOG4105K4P CoA-binding domain protein BCAH820_3611 ENOG4105C0H protease BCAH820_3612 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_3614 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCAH820_3615 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BCAH820_3616 ENOG4105W8X HesB YadR YfhF-family protein BCAH820_3622 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCAH820_3623 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCAH820_3626 ENOG4108JJA ABC, transporter BCAH820_3627 ENOG4108I0Z Aconitate hydratase BCAH820_3633 ENOG4105E5W Transporter BCAH820_3635 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCAH820_3639 ENOG4107F3J Amp-dependent synthetase and ligase BCAH820_3640 ENOG4107ZYJ bioY protein BCAH820_3641 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_3650 ENOG4107AYK membrAne BCAH820_3652 ENOG4105BZU Histidine kinase BCAH820_3653 ENOG4105FBA Phospholipase Carboxylesterase BCAH820_3654 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCAH820_3655 ENOG4105CK7 Sodium proline symporter BCAH820_3656 ENOG4105CBC glutamate synthase BCAH820_3657 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCAH820_3658 ENOG4108VJ1 Transcriptional regulator (CarD family BCAH820_3659 ENOG4108903 Formimidoylglutamase BCAH820_3675 ENOG4105EKQ RNA-directed DNA polymerase BCAH820_3679 ENOG4107QIV Cytochrome c biogenesis protein BCAH820_3681 ENOG4105CH2 amidohydrolase BCAH820_3683 ENOG4105CJ1 ABC, transporter BCAH820_3685 ENOG4107RSM transcriptional regulator BCAH820_3687 ENOG41067MG lrgb family BCAH820_3692 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCAH820_3695 ENOG4105BZ1 (ABC) transporter BCAH820_3696 ENOG4105BZ1 (ABC) transporter BCAH820_3700 ENOG4105D7V transposase BCAH820_3703 ENOG4105D5T phosphonate abc transporter BCAH820_3705 ENOG4105CGH 5'-nucleotidase BCAH820_3707 ENOG4108SVB resolvase BCAH820_3711 ENOG4105K7K Transcriptional regulator BCAH820_3713 ENOG4105C5F glutamine synthetase BCAH820_3714 ENOG4105KV4 Transcriptional regulator BCAH820_3715 ENOG4105CXI aluminum resistance protein BCAH820_3716 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCAH820_3717 ENOG4105EN6 Membrane BCAH820_3719 ENOG4106F1P AAA ATPase, central domain protein BCAH820_3725 ENOG41069ER domain protein BCAH820_3726 ENOG4105DM4 PTS System BCAH820_3727 ENOG4105DE4 1-phosphofructokinase BCAH820_3728 ENOG4105E98 transcriptional regulator DeoR family BCAH820_3729 ENOG4107QW4 alcohol dehydrogenase BCAH820_3730 ENOG4108SJC Membrane BCAH820_3733 ENOG4105C85 amino acid BCAH820_3734 ENOG4105C85 amino acid BCAH820_3739 ENOG4105TMB Formate nitrite transporter BCAH820_3740 ENOG4105K70 DNA-binding protein BCAH820_3741 ENOG4105C59 p-type ATPase BCAH820_3742 ENOG410681U heavy metal transport detoxification protein BCAH820_3743 ENOG4105VPX protein, conserved in bacteria BCAH820_3745 ENOG4105NIV Esterase BCAH820_3746 ENOG4105E0A ABC, transporter BCAH820_3750 ENOG4105CGK Exodeoxyribonuclease III BCAH820_3752 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCAH820_3753 ENOG4105D03 DNA-3-methyladenine glycosylase II BCAH820_3760 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BCAH820_3761 ENOG4105BZU Histidine kinase BCAH820_3765 ENOG41067MG lrgb family BCAH820_3768 ENOG4107TTQ Alpha beta hydrolase fold BCAH820_3769 ENOG4107YEI lmbE family BCAH820_3774 ENOG4105F0V Cell wall hydrolase BCAH820_3775 ENOG4107R6R udp-galactopyranose mutase BCAH820_3776 ENOG4105E0M Sulfatase BCAH820_3777 ENOG410890F Dynamin family BCAH820_3779 ENOG4107QHE Choloylglycine hydrolase BCAH820_3785 ENOG4105DQU oxidoreductase, subunit beta BCAH820_3786 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCAH820_3787 ENOG4108IGT Dipeptidase BCAH820_3788 ENOG4105MCT stage V sporulation protein S BCAH820_3789 ENOG4105D48 metallophosphoesterase BCAH820_3794 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCAH820_3797 ENOG4105XZV Protein of unknown function (DUF3243) BCAH820_3798 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCAH820_3802 ENOG4105UIB (ABC) transporter BCAH820_3803 ENOG4108JQ9 ABC transporter BCAH820_3804 ENOG4105DIH basic membrane BCAH820_3805 ENOG4105FDP GntR family transcriptional regulator BCAH820_3806 ENOG4107QZI cell division protein FtsK BCAH820_3808 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCAH820_3810 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCAH820_3812 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCAH820_3813 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCAH820_3814 ENOG4105E35 Dipicolinate synthase subunit A BCAH820_3816 ENOG4105C1V Peptidase, M16 BCAH820_3820 ENOG4105DTN riboflavin biosynthesis protein ribF BCAH820_3821 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BCAH820_3823 ENOG4105W7A Protein of unknown function (DUF503) BCAH820_3826 ENOG4105VHM ribosomal protein BCAH820_3827 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCAH820_3828 ENOG4105CHV Transcription elongation factor NusA BCAH820_3830 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCAH820_3832 ENOG4105DZP Membrane-associated zinc metalloprotease BCAH820_3833 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BCAH820_3834 ENOG4105KNE Phosphatidate cytidylyltransferase BCAH820_3843 ENOG4108HE4 integrase family BCAH820_3845 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCAH820_3846 ENOG4105C79 DNA protecting protein DprA BCAH820_3847 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCAH820_3851 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCAH820_3857 ENOG4105VB6 UPF0109 protein BCAH820_3861 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCAH820_3862 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCAH820_3865 ENOG4105CHR reductase BCAH820_3866 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCAH820_3869 ENOG4105CB5 ATP-dependent DNA helicase recG BCAH820_3870 ENOG4105DP4 dak2 domain fusion protein ylov BCAH820_3871 ENOG4108ZAA Alkaline-shock protein BCAH820_3873 ENOG4105FJ0 thiamine BCAH820_3874 ENOG4105DJV ribulose-phosphate 3-epimerase BCAH820_3875 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BCAH820_3876 ENOG4105D9P serine threonine protein kinase BCAH820_3877 ENOG4108ZF3 Phosphatase BCAH820_3879 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCAH820_3881 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCAH820_3882 ENOG4105C25 Primosomal protein n' BCAH820_3883 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCAH820_3887 ENOG4105DSJ YicC domain protein BCAH820_3889 ENOG4105F23 Fibronectin-binding protein BCAH820_3890 ENOG4105DC7 peptidase M24 BCAH820_3901 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BCAH820_3906 ENOG4105C34 Pseudouridine synthase BCAH820_3911 ENOG4105DBK s4 domain protein BCAH820_3912 ENOG41067XK integral membrane protein BCAH820_3914 ENOG4105DFA alanine racemase domain protein BCAH820_3915 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCAH820_3916 ENOG4105WR5 sporulation protein, YlmC YmxH family BCAH820_3918 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_3921 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCAH820_3922 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCAH820_3923 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BCAH820_3924 ENOG4105D4A Cell wall formation (By similarity) BCAH820_3925 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BCAH820_3926 ENOG4105CNI cell division protein FtsW BCAH820_3929 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCAH820_3930 ENOG4105CJN penicillin-binding protein BCAH820_3931 ENOG4105CJN penicillin-binding protein BCAH820_3932 ENOG41068DC Essential cell division protein (By similarity) BCAH820_3939 ENOG4105KNH Nucleic acid-binding protein BCAH820_3941 ENOG41063PX domain protein BCAH820_3942 ENOG4105D78 K07001 NTE family protein BCAH820_3944 ENOG4105H20 Sporulation integral membrane protein YlbJ BCAH820_3945 ENOG4106H78 methyltransferase BCAH820_3949 ENOG4107TB6 phosphoglycerate mutase BCAH820_3952 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCAH820_3962 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCAH820_3963 ENOG4105CNI cell division protein FtsW BCAH820_3966 ENOG4108IAB Phoh family BCAH820_3970 ENOG4105QA2 BCAH820_3971 ENOG4105CI3 gtp-binding protein typa BCAH820_3973 ENOG4105ECY inositol monophosphatase BCAH820_3977 ENOG4105CXN decarboxylase BCAH820_3986 ENOG4105CPP Dehydrogenase, E1 component BCAH820_3989 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCAH820_3990 ENOG4108X4Q Hydrolase BCAH820_3992 ENOG4105CN5 Metallo-Beta-Lactamase BCAH820_3993 ENOG4107ZYR domain protein BCAH820_4000 ENOG4108XRC Protein of unknown function (DUF458) BCAH820_4002 ENOG4107IN1 Protein of unknown function (DUF1797) BCAH820_4006 ENOG4105EPM Diguanylate phosphodiesterase BCAH820_4007 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCAH820_4010 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCAH820_4012 ENOG4105UIN BCAH820_4025 ENOG4108HGU Histidine kinase BCAH820_4027 ENOG4105CHM Aminotransferase BCAH820_4028 ENOG4105FKQ transcriptional regulator BCAH820_4030 ENOG4105EG2 ABC transporter, permease BCAH820_4032 ENOG4107FKK extracellular solute-binding protein family 1 BCAH820_4034 ENOG4105CG3 alpha amylase, catalytic region BCAH820_4043 ENOG4105CHU acetyl-coa acetyltransferase BCAH820_4051 ENOG4105DTD Dehydrogenase BCAH820_4055 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCAH820_4063 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCAH820_4064 ENOG4106TD9 Diguanylate cyclase BCAH820_4068 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCAH820_4071 ENOG4105CID antiterminator BCAH820_4073 ENOG4105FDP GntR family transcriptional regulator BCAH820_4075 ENOG4105CE4 GlcNAc 6-P deacetylase BCAH820_4082 ENOG4107ZE5 PPIases accelerate the folding of proteins BCAH820_4083 ENOG4105PTM secreted protein BCAH820_4084 ENOG4105J7I hydrolase BCAH820_4086 ENOG4105G6R Stage v sporulation protein ae BCAH820_4088 ENOG4105CZ3 stage V sporulation protein ad BCAH820_4089 ENOG41090VF Stage v sporulation protein ac BCAH820_4093 ENOG4105C8J )-transporter BCAH820_4094 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_4096 ENOG41082AN stage II sporulation protein BCAH820_4097 ENOG4105DZ1 carboxypeptidase BCAH820_4098 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCAH820_4099 ENOG4105DVE abc transporter atp-binding protein BCAH820_4108 ENOG4105D7N magnesium and cobalt transport protein CorA BCAH820_4113 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCAH820_4115 ENOG4105I3K Ferric uptake regulator, Fur family BCAH820_4116 ENOG4105MZ9 stage II sporulation protein m BCAH820_4120 ENOG4105CPC Aldo Keto reductase BCAH820_4122 ENOG4105RHY Pfam:UPF0157 BCAH820_4126 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCAH820_4128 ENOG4105ETE Transcriptional regulator (LacI family BCAH820_4129 ENOG4108YM7 Gcn5-related n-acetyltransferase BCAH820_4133 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCAH820_4134 ENOG4108R6K riboflavin synthase, subunit alpha BCAH820_4138 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BCAH820_4139 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCAH820_4140 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCAH820_4141 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BCAH820_4143 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCAH820_4146 ENOG4105DFD Na H antiporter BCAH820_4147 ENOG4105CGH 5'-nucleotidase BCAH820_4155 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BCAH820_4158 ENOG4108IXY short-chain dehydrogenase reductase BCAH820_4159 ENOG41069FQ Metallo-beta-lactamase superfamily BCAH820_4160 ENOG4105II7 pyrroline-5-carboxylate reductase BCAH820_4161 ENOG4105EJQ L-serine dehydratase BCAH820_4166 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCAH820_4167 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCAH820_4168 ENOG4105D9U N-acetyltransferase BCAH820_4170 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCAH820_4171 ENOG4108QEG Membrane BCAH820_4172 ENOG4105CDA abc transporter atp-binding protein BCAH820_4173 ENOG4105E5Q amino acid AbC transporter BCAH820_4174 ENOG4108HW3 (ABC) transporter BCAH820_4177 ENOG4105G7B Protein of unknown function (DUF2992) BCAH820_4178 ENOG4105E09 nadh pyrophosphatase BCAH820_4180 ENOG4105C7S Dehydrogenase BCAH820_4181 ENOG4105CPP Dehydrogenase, E1 component BCAH820_4185 ENOG4107RDP Dehydrogenase BCAH820_4187 ENOG4108JUB Transcriptional regulator BCAH820_4189 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCAH820_4192 ENOG4107QQR Sporulation BCAH820_4193 ENOG4105S1Z Stage IV sporulation protein B BCAH820_4194 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCAH820_4196 ENOG4105DX0 Hemolysin A BCAH820_4198 ENOG4105CTB Polyprenyl synthetase BCAH820_4203 ENOG4108ZSR alkaline shock protein BCAH820_4204 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCAH820_4208 ENOG410644B Stage III sporulation protein af BCAH820_4210 ENOG4105KQ4 Stage iii sporulation protein ad BCAH820_4211 ENOG4108CQH stage III sporulation protein AC BCAH820_4212 ENOG4105KR5 Stage iii sporulation protein BCAH820_4213 ENOG4105CD2 stage iii sporulation protein aa BCAH820_4218 ENOG4105DC7 peptidase M24 BCAH820_4221 ENOG4105CBJ Metal-dependent enzyme BCAH820_4222 ENOG4107YBY Hydrolase BCAH820_4228 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BCAH820_4229 ENOG4105WZW rhodanese family BCAH820_4233 ENOG41080TC multidrug resistance protein BCAH820_4241 ENOG4105CJ1 ABC, transporter BCAH820_4242 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCAH820_4248 ENOG4105C0D helicase BCAH820_4273 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BCAH820_4274 ENOG4105C3R Methionine synthase BCAH820_4276 ENOG4105C28 cystathionine BCAH820_4277 ENOG4105C28 cystathionine BCAH820_4281 ENOG4105C5X domain protein BCAH820_4283 ENOG4105DKQ ROK family BCAH820_4285 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCAH820_4288 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCAH820_4289 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCAH820_4290 ENOG4105E2Z phosphate ABC transporter (Permease BCAH820_4291 ENOG4105C8U phosphate abc transporter BCAH820_4292 ENOG4105PWN phosphate abc transporter BCAH820_4293 ENOG4107RF6 penicillin-binding protein BCAH820_4295 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCAH820_4301 ENOG4105N80 Ferric uptake regulator, Fur family BCAH820_4303 ENOG4105FDK ABC transporter BCAH820_4304 ENOG4108JYZ YitT family BCAH820_4305 ENOG41069ZM Protein of unknown function (DUF2624) BCAH820_4311 ENOG4105EGD dinuclear metal center protein, YbgI family BCAH820_4314 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_4315 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCAH820_4322 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCAH820_4323 ENOG4105KG3 cytidine deaminase BCAH820_4324 ENOG4107YR5 Diacylglycerol kinase BCAH820_4326 ENOG4105CTJ Metal Dependent Phosphohydrolase BCAH820_4327 ENOG4105C9A Phoh family BCAH820_4329 ENOG41068P3 sporulation protein YqfC BCAH820_4330 ENOG4105KTH gatB Yqey BCAH820_4332 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCAH820_4333 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCAH820_4337 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BCAH820_4339 ENOG4105CSA Coproporphyrinogen iii oxidase BCAH820_4340 ENOG4105KVH Transcriptional regulator BCAH820_4345 ENOG4105TQK DNA polymerase iii, delta' subunit BCAH820_4347 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCAH820_4348 ENOG4108UK2 deaminase BCAH820_4349 ENOG4105KQC Competence protein BCAH820_4351 ENOG4105DXX methyltransferase BCAH820_4353 ENOG4108WF2 Metal Dependent Phosphohydrolase BCAH820_4355 ENOG410812S Rna-binding protein BCAH820_4357 ENOG4105CQW ribosome biogenesis GTPase YqeH BCAH820_4358 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCAH820_4361 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_4362 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BCAH820_4393 ENOG410682Q Phage transcriptional regulator, ArpU BCAH820_4407 ENOG4105CDU Replicative dna helicase BCAH820_4414 ENOG4108IMY Transcriptional regulator BCAH820_4418 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_4422 ENOG4108TVJ Nitroreductase BCAH820_4426 ENOG4105G6Z alkaline phosphatase BCAH820_4429 ENOG4108MUZ hydrolase BCAH820_4436 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCAH820_4438 ENOG4105MIR Phenylalanine 4-monooxygenase BCAH820_4440 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCAH820_4448 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCAH820_4449 ENOG4108V5C ABC transporter BCAH820_4451 ENOG4108EKI Dehydrogenase BCAH820_4452 ENOG4105C28 cystathionine BCAH820_4458 ENOG4107XRG penicillin-binding protein BCAH820_4461 ENOG4105CFP Peptidase U32 BCAH820_4462 ENOG4105XYU peptidase (U32 family) BCAH820_4463 ENOG4108VQJ O-methyltransferase BCAH820_4464 ENOG4105HHA aminodeoxychorismate lyase BCAH820_4470 ENOG4105C02 permease BCAH820_4473 ENOG41060CR BCAH820_4474 ENOG4105C7H Helicase, RecD TraA family BCAH820_4477 ENOG4105C3J Cysteine desulfurase BCAH820_4479 ENOG4105D1H recombination factor protein RarA BCAH820_4480 ENOG4108VCI transcription factor, rsfa family BCAH820_4481 ENOG4105CUZ uba thif-type nad fad binding protein BCAH820_4483 ENOG4105CUT histidyl-tRNA synthetase BCAH820_4487 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCAH820_4489 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCAH820_4490 ENOG41076HS cation diffusion facilitator family transporter BCAH820_4491 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCAH820_4493 ENOG4105CKP Polysaccharide Biosynthesis Protein BCAH820_4494 ENOG4108QG2 Membrane BCAH820_4496 ENOG4105VIE preprotein translocase, subunit YajC BCAH820_4499 ENOG41061AI Protein of unknown function (DUF2905) BCAH820_4501 ENOG4108HUF Transporter BCAH820_4503 ENOG4108IPJ Membrane BCAH820_4504 ENOG41082BM Transcriptional regulator, arsr family BCAH820_4509 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCAH820_4510 ENOG4108IYU L-aspartate oxidase BCAH820_4513 ENOG4108RPX mosc domain containing protein BCAH820_4514 ENOG4105CQC Prephenate dehydratase BCAH820_4518 ENOG4105EWM Histidine kinase BCAH820_4523 ENOG4105X36 (ribosomal) protein BCAH820_4525 ENOG4105C03 ribonuclease BCAH820_4528 ENOG4107QMS site-determining protein BCAH820_4531 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCAH820_4532 ENOG4105DFF Rod shape-determining protein mreb BCAH820_4538 ENOG4105ZX1 Transposase C BCAH820_4539 ENOG4108KU9 integrase family BCAH820_4540 ENOG4108FPN Integrase BCAH820_4544 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCAH820_4545 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BCAH820_4547 ENOG41068KH stage VI sporulation protein D BCAH820_4549 ENOG4105D52 delta-aminolevulinic acid dehydratase BCAH820_4554 ENOG4105K56 Transcriptional regulator BCAH820_4558 ENOG4108IUQ atp-dependent protease BCAH820_4564 ENOG4108QCI YvbH-like oligomerisation region BCAH820_4569 ENOG4105M59 Phosphodiesterase, mj0936 family BCAH820_4570 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BCAH820_4572 ENOG4108XJQ germination protein BCAH820_4574 ENOG4108PCX Major Facilitator BCAH820_4577 ENOG4105KBX Transcriptional regulator, TetR family BCAH820_4580 ENOG4105PFC Transcriptional regulator BCAH820_4583 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCAH820_4590 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCAH820_4606 ENOG4105DZC cytosine deaminase BCAH820_4607 ENOG4105DZC cytosine deaminase BCAH820_4608 ENOG4105DEF Extracellular solute-binding protein, family 5 BCAH820_4609 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCAH820_4612 ENOG4108JQ7 (ABC) transporter BCAH820_4613 ENOG4108HRK Histidine kinase BCAH820_4614 ENOG4105DY9 regulatoR BCAH820_4616 ENOG41067S9 phage shock protein C, PspC BCAH820_4617 ENOG4108JCI Transcriptional regulator BCAH820_4619 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCAH820_4620 ENOG4108Z40 Transcriptional regulator BCAH820_4621 ENOG4105RHA ABC transporter, permease BCAH820_4622 ENOG4108IUX (ABC) transporter BCAH820_4623 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCAH820_4624 ENOG4105ER2 Ompa motb domain protein BCAH820_4625 ENOG4105E14 MotA TolQ exbB proton channel BCAH820_4626 ENOG4108VXD carboxy-peptidase BCAH820_4628 ENOG4105E33 succinate dehydrogenase BCAH820_4630 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCAH820_4633 ENOG4105K63 Thioredoxin BCAH820_4634 ENOG4105C10 Electron transfer flavoprotein BCAH820_4635 ENOG4105BZJ Electron transfer flavoprotein BCAH820_4636 ENOG41060WC Enoyl-CoA hydratase BCAH820_4637 ENOG4107Z3H Transcriptional regulator, TetR family BCAH820_4638 ENOG4105CEY Amp-dependent synthetase and ligase BCAH820_4641 ENOG4105J76 Periplasmic binding protein BCAH820_4642 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCAH820_4650 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_4653 ENOG4105DR4 Methyltransferase BCAH820_4657 ENOG4105KFN sortase, SrtB family BCAH820_4658 ENOG4105E0A ABC, transporter BCAH820_4661 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCAH820_4662 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCAH820_4664 ENOG4105FE9 pseudouridine synthase BCAH820_4666 ENOG4105DCG PHP domain protein BCAH820_4673 ENOG4105C5S asparaginyl-tRNA synthetase BCAH820_4674 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BCAH820_4676 ENOG4108RWN rrna methyltransferase BCAH820_4683 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCAH820_4684 ENOG4105CW7 secretion protein, HlyD family BCAH820_4685 ENOG4108JGH Tetr family transcriptional regulator BCAH820_4686 ENOG4105CN9 Peptidase m42 family protein BCAH820_4690 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCAH820_4691 ENOG4105C22 threonyL-tRNA synthetase BCAH820_4692 ENOG4108TDW sporulation protein YtxC BCAH820_4696 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCAH820_4698 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCAH820_4699 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BCAH820_4701 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BCAH820_4702 ENOG4105C2M dna polymerase I BCAH820_4703 ENOG4105BZU Histidine kinase BCAH820_4704 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_4708 ENOG4108HMX isocitrate dehydrogenase (NADP) BCAH820_4709 ENOG4105BZN citrate synthase BCAH820_4711 ENOG4108REF Sporulation integral membrane protein ytvi BCAH820_4712 ENOG4105FS0 cytoplasmic membrane protein BCAH820_4717 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCAH820_4718 ENOG4105C6K Malic enzyme BCAH820_4719 ENOG4105C0B DNA polymerase III (alpha subunit) BCAH820_4720 ENOG4105VV2 BCAH820_4722 ENOG4105SFS phosphoesterase RecJ domain protein BCAH820_4730 ENOG4105DC7 peptidase M24 BCAH820_4739 ENOG41082W1 Cupin 2, conserved barrel domain protein BCAH820_4743 ENOG4107YZX Universal stress protein BCAH820_4751 ENOG4108JYZ YitT family BCAH820_4757 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCAH820_4758 ENOG4105KBJ sporulation protein ytfj BCAH820_4761 ENOG4105EFZ amidohydrolase BCAH820_4763 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCAH820_4768 ENOG4106KR7 LysR family Transcriptional regulator BCAH820_4770 ENOG4105U5Y Transcriptional regulator BCAH820_4772 ENOG4105C28 cystathionine BCAH820_4776 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCAH820_4778 ENOG4105EMN RNA polymerase sigma factor BCAH820_4781 ENOG4105F1V Acetoin utilization protein BCAH820_4782 ENOG4105W87 Cbs domain BCAH820_4783 ENOG4105DGU Histone deacetylase BCAH820_4786 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCAH820_4788 ENOG4107SNB ankyrin repeat protein YahD BCAH820_4789 ENOG4105EP9 oxidoreductase BCAH820_4795 ENOG4105ETE Transcriptional regulator (LacI family BCAH820_4799 ENOG4105C88 aminopeptidase BCAH820_4803 ENOG4105K7K Transcriptional regulator BCAH820_4809 ENOG4108VDD TRNA binding domain protein BCAH820_4815 ENOG4105C8F Beta-lactamase domain protein BCAH820_4818 ENOG4108V15 phosphotransferase enzyme family BCAH820_4819 ENOG4108IUM Glycogen debranching enzyme BCAH820_4821 ENOG4107QSE Dipeptidase BCAH820_4822 ENOG4105YW5 deoR family transcriptional regulator BCAH820_4825 ENOG4105CBX hi0933 family BCAH820_4833 ENOG4108VJ1 Transcriptional regulator (CarD family BCAH820_4834 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCAH820_4838 ENOG4108ZAF Molybdopterin BCAH820_4839 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCAH820_4840 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCAH820_4842 ENOG4105D06 uba thif-type nad fad binding protein BCAH820_4843 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCAH820_4847 ENOG41085GJ domain protein BCAH820_4849 ENOG4105DWV Homoserine O-trans-acetylase BCAH820_4853 ENOG4108B31 Spore germination protein BCAH820_4862 ENOG410605W Major Facilitator BCAH820_4863 ENOG4107S91 Sodium hydrogen exchanger BCAH820_4864 ENOG4105NCW Trka-c domain protein BCAH820_4867 ENOG4105C19 ABC transporter BCAH820_4871 ENOG4105N5T Radical SAM Protein BCAH820_4878 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCAH820_4879 ENOG4108Z0R Transferase BCAH820_4880 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCAH820_4881 ENOG4105BZF Glycosyl transferase (Group 1 BCAH820_4883 ENOG4108RIR Molybdenum cofactor biosynthesis protein BCAH820_4894 ENOG4105BZU Histidine kinase BCAH820_4895 ENOG4105BZU Histidine kinase BCAH820_4896 ENOG4107S9D Alpha beta hydrolase BCAH820_4897 ENOG4107T7U Sulfatase BCAH820_4900 ENOG4105D2X ABC transporter substrate-binding protein BCAH820_4902 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCAH820_4905 ENOG4107XGZ Hydrolase BCAH820_4912 ENOG4108V2W Carbonate dehydratase BCAH820_4914 ENOG4105C4M (Ubiquinol oxidase) subunit I BCAH820_4915 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCAH820_4925 ENOG41087YS Phage shock protein A BCAH820_4931 ENOG4105BZU Histidine kinase BCAH820_4932 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_4937 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCAH820_4938 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCAH820_4943 ENOG4107ZTW SNARE associated Golgi BCAH820_4946 ENOG4105C19 ABC transporter BCAH820_4947 ENOG41086D8 Transcriptional regulator BCAH820_4955 ENOG4105C6Z Gluconate BCAH820_4956 ENOG4105FDP GntR family transcriptional regulator BCAH820_4960 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCAH820_4964 ENOG4105DTQ mandelate racemase muconate lactonizing BCAH820_4966 ENOG4108IPT Naphthoate synthase BCAH820_4967 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCAH820_4969 ENOG4105E4F Isochorismate synthase BCAH820_4970 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCAH820_4972 ENOG4105VEQ Cold shock protein BCAH820_4979 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BCAH820_4981 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCAH820_5006 ENOG4105KT7 mgtC SapB transporter BCAH820_5008 ENOG4107PBV potassium channel BCAH820_5010 ENOG4105WG9 Conserved Protein BCAH820_5012 ENOG4105CHM Aminotransferase BCAH820_5013 ENOG4108ZB6 transcriptional regulator AsnC family BCAH820_5014 ENOG4105C5I Dehydrogenase BCAH820_5015 ENOG4108MUZ hydrolase BCAH820_5017 ENOG4105C87 Aminotransferase class I and II BCAH820_5020 ENOG4105Y38 Kinase-associated protein B BCAH820_5022 ENOG4107R3E Citrate transporter BCAH820_5025 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCAH820_5026 ENOG4105KA0 thioesterase Superfamily protein BCAH820_5029 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCAH820_5033 ENOG41069ER domain protein BCAH820_5036 ENOG4105CEP NADH dehydrogenase BCAH820_5042 ENOG4105EWC Purine nucleoside phosphorylase BCAH820_5044 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCAH820_5049 ENOG4108JJA ABC, transporter BCAH820_5050 ENOG4105C4B ABC transporter, permease BCAH820_5051 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCAH820_5056 ENOG41083MR nifu domain-containing protein BCAH820_5059 ENOG4108W5N phosphatidylglycerophosphatase a BCAH820_5061 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCAH820_5063 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCAH820_5066 ENOG4105CBT Fructose-1,6-bisphosphatase BCAH820_5069 ENOG4105MMD transcriptional regulator BCAH820_5070 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCAH820_5071 ENOG4107TXC Transcriptional regulator BCAH820_5072 ENOG41090T1 Membrane BCAH820_5077 ENOG4105FAA peptidase M23 BCAH820_5079 ENOG4105KZD Domain of unknown function (DUF1805) BCAH820_5080 ENOG4107R8B 5'-nucleotidase BCAH820_5084 ENOG4105DIW FeS assembly protein SUFB BCAH820_5085 ENOG4108UNV SUF system FeS assembly protein, NifU family BCAH820_5086 ENOG4105C9B Cysteine desulfurase BCAH820_5087 ENOG4105JRK feS assembly protein SufD BCAH820_5088 ENOG4105C3K feS assembly ATPase SufC BCAH820_5089 ENOG4105D01 (LipO)protein BCAH820_5090 ENOG4105D01 (LipO)protein BCAH820_5091 ENOG4108UMI ABC transporter, permease BCAH820_5098 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCAH820_5106 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCAH820_5114 ENOG4108W8B Beta-lactamase domain protein BCAH820_5115 ENOG4105C1G acyl-Coa dehydrogenase BCAH820_5117 ENOG4105CHU acetyl-coa acetyltransferase BCAH820_5120 ENOG4105DZ1 carboxypeptidase BCAH820_5124 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCAH820_5128 ENOG4108SUT Major Facilitator Superfamily BCAH820_5129 ENOG4107R7I amino acid BCAH820_5131 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCAH820_5133 ENOG4107AYK membrAne BCAH820_5141 ENOG4107ZTW SNARE associated Golgi BCAH820_5143 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCAH820_5144 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_5145 ENOG4105BZU Histidine kinase BCAH820_5149 ENOG4105C8Q Methyl-accepting chemotaxis BCAH820_5150 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCAH820_5151 ENOG4105VG1 fes assembly suf system protein BCAH820_5152 ENOG4105D4Y metalloprotease BCAH820_5156 ENOG4107S91 Sodium hydrogen exchanger BCAH820_5157 ENOG4105NCW Trka-c domain protein BCAH820_5159 ENOG4108RMU ferritin dps family protein BCAH820_5162 ENOG4108URH decarboxylase BCAH820_5166 ENOG4105D9N nucleoside BCAH820_5167 ENOG4105D9N nucleoside BCAH820_5170 ENOG4108RYK Nad-dependent epimerase dehydratase BCAH820_5174 ENOG4105CV8 reductase BCAH820_5175 ENOG4105F27 Major Facilitator BCAH820_5176 ENOG4105KVH Transcriptional regulator BCAH820_5179 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCAH820_5180 ENOG4105D4A Cell wall formation (By similarity) BCAH820_5184 ENOG4105C8Q Methyl-accepting chemotaxis BCAH820_5186 ENOG4105WMR Protein CrcB homolog BCAH820_5190 ENOG4108MK9 spermidine N(1)-acetyltransferase BCAH820_5191 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BCAH820_5194 ENOG4108IPW abc transporter atp-binding protein BCAH820_5195 ENOG4105CM4 permease protein BCAH820_5199 ENOG4105EWM Histidine kinase BCAH820_5200 ENOG4105CJZ response regulator BCAH820_5201 ENOG4105C19 ABC transporter BCAH820_5204 ENOG4105C19 ABC transporter BCAH820_5214 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCAH820_5216 ENOG4105XZU Preprotein translocase, subunit SecG BCAH820_5217 ENOG41067MG lrgb family BCAH820_5221 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BCAH820_5227 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_5231 ENOG41090VF Stage v sporulation protein ac BCAH820_5232 ENOG4105CZ3 stage V sporulation protein ad BCAH820_5235 ENOG4105H67 Protein of unknown function (DUF421) BCAH820_5236 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCAH820_5237 ENOG4105KRI phosphocarrier protein (HPr BCAH820_5239 ENOG4105CHW UPF0052 protein BCAH820_5241 ENOG4108Z4K mutator MutT protein BCAH820_5243 ENOG4105C3M thioredoxin reductase BCAH820_5245 ENOG4108S4C acetyltransferase BCAH820_5249 ENOG41086DT Membrane protein of unknown function BCAH820_5251 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCAH820_5255 ENOG4107TXC Transcriptional regulator BCAH820_5262 ENOG4105HMI Membrane BCAH820_5263 ENOG4105DUM transcriptional regulator, lysR family BCAH820_5265 ENOG4108WS4 fmn reductase BCAH820_5268 ENOG4105BZ1 (ABC) transporter BCAH820_5270 ENOG4105CN1 protease BCAH820_5271 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCAH820_5272 ENOG4105CAK Cell division ATP-binding protein ftsE BCAH820_5278 ENOG4105MS2 ribosomal subunit Interface protein BCAH820_5280 ENOG4105VEQ Cold shock protein BCAH820_5281 ENOG41081UC Inherit from COG: Competence protein BCAH820_5284 ENOG4105KVH Transcriptional regulator BCAH820_5287 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCAH820_5288 ENOG4108KGH TRANSCRIPTIONal BCAH820_5289 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCAH820_5290 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCAH820_5291 ENOG4105ESV Glycosyl transferase, family 4 BCAH820_5293 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCAH820_5297 ENOG4105F8D glycoside hydrolase family 4 BCAH820_5298 ENOG4105VCP PTS System BCAH820_5299 ENOG4105CK1 PTS System BCAH820_5301 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BCAH820_5302 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCAH820_5303 ENOG4105VCP PTS System BCAH820_5305 ENOG4105VZJ PTS System BCAH820_5308 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCAH820_5309 ENOG4105ECB domain protein BCAH820_5310 ENOG4107RSM transcriptional regulator BCAH820_5317 ENOG4105DAA L-lactate BCAH820_5319 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCAH820_5321 ENOG4105E0M Sulfatase BCAH820_5327 ENOG4107R8N Glycosyl transferase, family 2 BCAH820_5329 ENOG4105C94 Transporter BCAH820_5330 ENOG41069ER domain protein BCAH820_5335 ENOG4105KBK Zinc finger, swim domain protein BCAH820_5336 ENOG4105C0D helicase BCAH820_5342 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCAH820_5345 ENOG4107RBB ABC transporter, permease BCAH820_5346 ENOG4105C19 ABC transporter BCAH820_5349 ENOG4105CXY transporter BCAH820_5352 ENOG4105BZU Histidine kinase BCAH820_5353 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_5354 ENOG4105CMR udp-glucose 4-epimerase BCAH820_5359 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCAH820_5360 ENOG4105EY8 ABC transporter BCAH820_5370 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCAH820_5373 ENOG4105FRN stage II sporulation protein BCAH820_5376 ENOG4105DY9 regulatoR BCAH820_5380 ENOG4106778 Protein of unknown function (DUF1146) BCAH820_5381 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCAH820_5382 ENOG4105C8S subunit m BCAH820_5383 ENOG4105D65 subunit l BCAH820_5388 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCAH820_5389 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCAH820_5391 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCAH820_5392 ENOG4105BZU Histidine kinase BCAH820_5402 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCAH820_5403 ENOG41062M3 atp synthase BCAH820_5409 ENOG4108YZG isomerase BCAH820_5412 ENOG4108VGI doxx family BCAH820_5413 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCAH820_5417 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCAH820_5419 ENOG4108ZXQ stage ii sporulation protein r BCAH820_5420 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCAH820_5421 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCAH820_5424 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCAH820_5425 ENOG4105CBT Fructose-1,6-bisphosphatase BCAH820_5426 ENOG4105CBT Fructose-1,6-bisphosphatase BCAH820_5427 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCAH820_5434 ENOG4105C1G acyl-Coa dehydrogenase BCAH820_5435 ENOG4105C1G acyl-Coa dehydrogenase BCAH820_5436 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCAH820_5438 ENOG4105DF6 Fe-S oxidoreductase BCAH820_5441 ENOG4105BZU Histidine kinase BCAH820_5445 ENOG4105BZU Histidine kinase BCAH820_5446 ENOG4105KCT ABC transporter BCAH820_5447 ENOG4108M15 ABC transporter BCAH820_5448 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCAH820_5450 ENOG4105IIU Aminopeptidase BCAH820_5454 ENOG4105EMN RNA polymerase sigma factor BCAH820_5456 ENOG410684U Domain of unknown function (DUF1934) BCAH820_5461 ENOG4105CYW agmatinase BCAH820_5463 ENOG4105DXB Major Facilitator superfamily BCAH820_5464 ENOG4107SWG transcriptional regulator MERR family BCAH820_5466 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCAH820_5467 ENOG4105BZ4 penicillin-binding protein BCAH820_5468 ENOG4108XFG YwhD family BCAH820_5469 ENOG4108Z4T Peptidase M50 BCAH820_5470 ENOG41069HH 4-oxalocrotonate tautomerase BCAH820_5471 ENOG4105DCI Phosphohydrolase BCAH820_5472 ENOG4108MES Periplasmic binding protein BCAH820_5473 ENOG4105E0A ABC, transporter BCAH820_5474 ENOG4105EHG Permease protein BCAH820_5475 ENOG4105DQ5 transport system permease protein BCAH820_5477 ENOG4108VCI transcription factor, rsfa family BCAH820_5481 ENOG4108IJ2 phosphate acetyltransferase BCAH820_5485 ENOG4108VKI Cell wall hydrolase BCAH820_5489 ENOG4107SVH Potassium channel protein BCAH820_5491 ENOG410667J hydrolase BCAH820_5492 ENOG4105VCH membrane BCAH820_5494 ENOG4108TU7 Inherit from COG: (ABC) transporter BCAH820_5495 ENOG4105CJ1 ABC, transporter BCAH820_5496 ENOG41090WU lipolytic protein G-D-S-L family BCAH820_5499 ENOG4105D6E homoserine dehydrogenase BCAH820_5504 ENOG4108Y4K DNA-binding transcriptional activator BCAH820_5506 ENOG4105WH1 Two component transcriptional regulator luxr family BCAH820_5507 ENOG4105BZU Histidine kinase BCAH820_5508 ENOG4105DWF phosphomethylpyrimidine kinase BCAH820_5509 ENOG4105BZU Histidine kinase BCAH820_5510 ENOG4105VCD cytoplasmic protein BCAH820_5511 ENOG4105D22 carbon starvation protein BCAH820_5512 ENOG4105DY9 regulatoR BCAH820_5513 ENOG41079KZ Major Facilitator Superfamily BCAH820_5518 ENOG4105EN6 Membrane BCAH820_5519 ENOG4106YBV Methyl-accepting chemotaxis BCAH820_5521 ENOG4108S4H thioesterase Superfamily protein BCAH820_5523 ENOG4105JEU Glycosyl transferase, family 2 BCAH820_5524 ENOG4105C5H ABC transporter BCAH820_5528 ENOG4105CKK Glycosyl transferase, family 2 BCAH820_5529 ENOG41067SE Tetr family transcriptional regulator BCAH820_5531 ENOG4105E0X reductase BCAH820_5533 ENOG4106F5Q Membrane BCAH820_5536 ENOG4105DY9 regulatoR BCAH820_5537 ENOG4108HRK Histidine kinase BCAH820_5538 ENOG4107RGD Major Facilitator superfamily BCAH820_5541 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCAH820_5543 ENOG4105IW1 AmiS UreI transporter BCAH820_5545 ENOG4105CMR udp-glucose 4-epimerase BCAH820_5546 ENOG4108UT2 hemolysin iii BCAH820_5548 ENOG4105C1J atp-dependent rna helicase BCAH820_5551 ENOG4105DPN Oligoendopeptidase f BCAH820_5553 ENOG4107Y5K Resolvase BCAH820_5554 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCAH820_5564 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BCAH820_5567 ENOG4105C0H protease BCAH820_5568 ENOG4105Q2H domain protein BCAH820_5571 ENOG4105BZU Histidine kinase BCAH820_5572 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_5578 ENOG4105CDU Replicative dna helicase BCAH820_5580 ENOG4105BZR domain protein BCAH820_5581 ENOG4108XMW Membrane BCAH820_5583 ENOG4108UUM single-stranded DNA-binding protein BCAH820_5585 ENOG4105C3G gtp-binding protein BCAH820_5586 ENOG4105VDK protein, conserved in bacteria BCAH820_5587 ENOG4105D8X mechanosensitive ion channel BCAH820_5588 ENOG4108ZDA Sporulation protein YyaC BCAH820_5589 ENOG4105FA0 parb-like partition protein BCAH820_5590 ENOG4107QJE Chromosome Partitioning Protein BCAH820_5594 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BCAH820_5596 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCAH820_B0002 ENOG4105C79 DNA protecting protein DprA BCAH820_B0008 ENOG4105D7V transposase BCAH820_B0013 ENOG4105EKQ RNA-directed DNA polymerase BCAH820_B0018 ENOG4105EKQ RNA-directed DNA polymerase BCAH820_B0052 ENOG4105VIZ double-strand break repair protein BCAH820_B0063 ENOG4105EKQ RNA-directed DNA polymerase BCAH820_B0064 ENOG4107QZI cell division protein FtsK BCAH820_B0093 ENOG4105D7V transposase BCAH820_B0122 ENOG41067XF inhibitor BCAH820_B0157 ENOG4108NHD germination protein BCAH820_B0159 ENOG410900G Protein of unknown function (DUF421) BCAH820_B0168 ENOG4105KVH Transcriptional regulator BCAH820_B0170 ENOG4105C4W S-formylglutathione hydrolase BCAH820_B0172 ENOG4105D9M gamma-glutamylcysteine synthetase BCAH820_B0178 ENOG4105DHF Membrane BCAH820_B0184 ENOG4105K70 DNA-binding protein BCAH820_B0194 ENOG4105KRN Transcriptional regulator, abrb family BCAH820_B0199 ENOG4105E1K spore germination protein BCAH820_B0200 ENOG4108B31 Spore germination protein BCAH820_B0203 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCAH820_B0204 ENOG4108QY0 Membrane BCAH820_B0207 ENOG4105CZ3 stage V sporulation protein ad BCAH820_B0208 ENOG41090VF Stage v sporulation protein ac BCAH820_B0211 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCAH820_B0214 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BCAH820_B0223 ENOG41086D8 Transcriptional regulator BCAH820_B0230 ENOG4108J59 Extracellular solute-binding protein, family 5 BCAH820_B0234 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCAH820_B0240 ENOG4108IBT Inherit from COG: transposase BCAH820_B0249 ENOG4108ZRV stage ii sporulation protein p BCAH820_B0253 ENOG4105BZU Histidine kinase BCAH820_B0254 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCAH820_B0255 ENOG4107R16 Multicopper oxidase BCAH820_B0257 ENOG4105CDA abc transporter atp-binding protein BCAH820_B0258 ENOG4105E5Q amino acid AbC transporter BCAH820_B0259 ENOG4105EAB amino acid AbC transporter BCAH820_B0261 ENOG4105K63 Thioredoxin BCAH820_B0278 ENOG4105DSE periplasmic solute binding protein BCAH820_B0279 ENOG4105VPX protein, conserved in bacteria BCAH820_B0280 ENOG4105C59 p-type ATPase BCAH820_B0290 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCAH820_B0293 ENOG41085FC arsR family transcriptional regulator BCAH820_B0294 ENOG4105CJ3 phosphate transporter BCAH820_B0295 ENOG41067QW Transcriptional regulator BCAH820_B0297 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCAH820_B0302 ENOG41082YX Transcriptional regulator, arsr family BCAH820_B0303 ENOG4105D6J arsenicaL-resistance protein BCAH820_B0311 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BCAH820_C0005 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BCAH820_C0006 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BCAH820_C0007 ENOG4108VKI Cell wall hydrolase BCAH820_C0008 ENOG4105VN1 Heat shock protein