locus-tag class description BCE_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCE_0003 ENOG410848D S4 domain protein YaaA BCE_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCE_0009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCE_0015 ENOG4105ZMH deoxynucleoside kinase BCE_0017 ENOG4105GTG Isochorismatase BCE_0019 ENOG4108Z6B deaminase BCE_0020 ENOG4105C6E dna polymerase iii BCE_0025 ENOG41067KS pro-sigma K processing BCE_0027 ENOG4105CXN decarboxylase BCE_0029 ENOG4105FA2 dna polymerase iii BCE_0030 ENOG4105MA4 psp1 domain protein BCE_0032 ENOG41060K3 Methyltransferase BCE_0034 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCE_0035 ENOG4105KRN Transcriptional regulator, abrb family BCE_0037 ENOG4105F8V Hydrolase, tatD family BCE_0038 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCE_0040 ENOG4105XFA sporulation peptidase YabG BCE_0041 ENOG4105W42 Veg protein BCE_0044 ENOG4105DFT pur operon repressor BCE_0045 ENOG4105KME endoribonuclease L-psp BCE_0048 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCE_0051 ENOG4108JA2 transcriptioN-repair coupling factor BCE_0052 ENOG4108M14 stage v sporulation protein t BCE_0054 ENOG4108IY2 MazG family BCE_0055 ENOG41082I2 s4 domain protein BCE_0056 ENOG4105VYY sporulation protein yabp BCE_0059 ENOG41060GV RNA binding s1 domain protein BCE_0062 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCE_0063 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCE_0066 ENOG4105C6T cysteine synthase BCE_0067 ENOG4105CRQ synthase (Component I) BCE_0068 ENOG4105DDQ anthranilate synthase BCE_0069 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCE_0070 ENOG4105EEI dihydropteroate synthase BCE_0071 ENOG4105KRF dihydroneopterin aldolase BCE_0072 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCE_0074 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCE_0079 ENOG4108Z0C Uvrb UvrC protein BCE_0082 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCE_0084 ENOG4105CTP PilT protein domain protein BCE_0088 ENOG4105D7W serine acetyltransferase BCE_0091 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCE_0092 ENOG4105M0M Tetracycline resistance protein BCE_0093 ENOG4105QIV RNA polymerase BCE_0096 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCE_0101 ENOG4107Y49 methyltransferase BCE_0104 ENOG4105XPM ribosomal protein BCE_0125 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCE_0130 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCE_0132 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCE_0134 ENOG41067V7 50S ribosomal protein L36 BCE_0141 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCE_0147 ENOG4105D1F ATP-binding protein BCE_0150 ENOG4108NMV polysaccharide deacetylase BCE_0155 ENOG4105C8B TIGR00159 family BCE_0156 ENOG4107U5W ybbr family BCE_0194 ENOG4108PSK reductase BCE_0195 ENOG4108UMI ABC transporter, permease BCE_0197 ENOG4105D01 (LipO)protein BCE_0198 ENOG4105CPQ Dehydrogenase BCE_0199 ENOG4105IQ5 FAD linked oxidase domain protein BCE_0202 ENOG4105C2C drug resistance transporter, Bcr CflA BCE_0205 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE_0206 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE_0207 ENOG4105C3U ABC transporter BCE_0208 ENOG4108JQ7 (ABC) transporter BCE_0212 ENOG4105U5Y Transcriptional regulator BCE_0214 ENOG4108J59 Extracellular solute-binding protein, family 5 BCE_0215 ENOG4108J59 Extracellular solute-binding protein, family 5 BCE_0219 ENOG4107XDY Nicotinamide Mononucleotide Transporter BCE_0221 ENOG4105E0C molybdate abc transporter BCE_0222 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCE_0223 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCE_0230 ENOG4105F6E Acyl-transferase BCE_0234 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCE_0237 ENOG4108RE7 deoxyribonuclease BCE_0239 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCE_0245 ENOG4105C5H ABC transporter BCE_0247 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCE_0248 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCE_0250 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE_0251 ENOG4105C3U ABC transporter BCE_0252 ENOG4108JQ7 (ABC) transporter BCE_0253 ENOG410667J hydrolase BCE_0260 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCE_0261 ENOG4105ERH Fumarylacetoacetate hydrolase BCE_0263 ENOG4105CUB amino acid BCE_0264 ENOG4108SC4 )-transporter BCE_0265 ENOG4105CPF Cell wall formation (By similarity) BCE_0266 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCE_0271 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCE_0272 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCE_0274 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCE_0278 ENOG4105K8N protein family UPF0079, ATPase BCE_0279 ENOG4105K8N protein family UPF0079, ATPase BCE_0280 ENOG41072GX Peptidase M22 Glycoprotease BCE_0281 ENOG410801F ribosomal-protein-alanine acetyltransferase BCE_0284 ENOG4105C5H ABC transporter BCE_0287 ENOG4108TYN CAAX amino terminal protease family protein BCE_0293 ENOG4105C7N Xanthine uracil vitamin C permease BCE_0295 ENOG4105BZU Histidine kinase BCE_0301 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE_0305 ENOG4108SHN Glycosyl transferase, family 2 BCE_0314 ENOG4105SX7 Transporter BCE_0317 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCE_0318 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCE_0319 ENOG4105C83 adenylosuccinate lyase BCE_0321 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCE_0326 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCE_0328 ENOG4105C12 Phosphoribosylglycinamide synthetase BCE_0334 ENOG4105C4R Atp-dependent dna helicase BCE_0340 ENOG4108W2Y isochorismatase BCE_0342 ENOG4108UMI ABC transporter, permease BCE_0343 ENOG4105D01 (LipO)protein BCE_0347 ENOG410834F Transcriptional regulator BCE_0348 ENOG4107I77 yiaA/B two helix domain BCE_0352 ENOG4105CBD Diacylglycerol kinase BCE_0353 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BCE_0354 ENOG4108JPW Aminotransferase BCE_0356 ENOG4105C26 Dehydrogenase BCE_0357 ENOG4105KPY Small multidrug resistance protein BCE_0362 ENOG4105D9N nucleoside BCE_0377 ENOG4105C2M dna polymerase I BCE_0378 ENOG4105W1N transcriptional regulator BCE_0382 ENOG4105XB7 anti-repressor protein BCE_0397 ENOG4105CAR Terminase, large subunit BCE_0398 ENOG4105EFC phage portal protein HK97 family BCE_0399 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCE_0420 ENOG4107TXC Transcriptional regulator BCE_0427 ENOG4105BZU Histidine kinase BCE_0430 ENOG4108W15 Protein of unknown function (DUF1456) BCE_0433 ENOG4105DTQ mandelate racemase muconate lactonizing BCE_0435 ENOG4105DFD Na H antiporter BCE_0440 ENOG4105D3R alkyl hydroperoxide reductase BCE_0444 ENOG4107W7X Aldolase BCE_0449 ENOG4105EHG Permease protein BCE_0450 ENOG4105DQ5 transport system permease protein BCE_0451 ENOG4108V5C ABC transporter BCE_0463 ENOG410756H nucleotidyltransferase BCE_0464 ENOG4105D2S major facilitator superfamily BCE_0467 ENOG4105E5Q amino acid AbC transporter BCE_0468 ENOG4105EAB amino acid AbC transporter BCE_0470 ENOG4105C8Q Methyl-accepting chemotaxis BCE_0475 ENOG4105C5B carbamate kinase BCE_0479 ENOG4105DNP FAD linked oxidase domain protein BCE_0480 ENOG4105DNP FAD linked oxidase domain protein BCE_0482 ENOG4105CI1 PTS System BCE_0488 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCE_0491 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component BCE_0495 ENOG4105C5H ABC transporter BCE_0503 ENOG41062JF Transcriptional regulator BCE_0507 ENOG4105DEU major facilitator superfamily BCE_0513 ENOG4108N0M stress protein BCE_0514 ENOG4106FN3 tellurium resistance protein BCE_0515 ENOG4106FN3 tellurium resistance protein BCE_0516 ENOG4107TS3 membrane protein, TerC BCE_0517 ENOG4108TTB tellurium resistance protein BCE_0521 ENOG4105KJF protein tyrosine phosphatase BCE_0523 ENOG4107U9T Pfam:Ribonuclease_BN BCE_0524 ENOG4105C59 p-type ATPase BCE_0525 ENOG4108IPJ Membrane BCE_0528 ENOG4105C3F Signal peptidase i BCE_0530 ENOG4107ZTW SNARE associated Golgi BCE_0533 ENOG410606W general stress protein BCE_0535 ENOG4105UPD Calcium Proton BCE_0545 ENOG4108JUB Transcriptional regulator BCE_0547 ENOG4108IQI permease BCE_0553 ENOG4105CSV Glutaminase BCE_0555 ENOG4108A04 Beta-lactamase BCE_0559 ENOG4105CKK Glycosyl transferase, family 2 BCE_0560 ENOG4107QQG Dehydrogenase BCE_0561 ENOG4105C3I Nad-dependent epimerase dehydratase BCE_0564 ENOG4105F1A Pyruvate formate-lyase BCE_0569 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BCE_0570 ENOG4105ECP epimerase BCE_0576 ENOG41067AE Membrane-bound metal-dependent hydrolase BCE_0577 ENOG4105CEN a g-specific adenine glycosylase BCE_0578 ENOG4106BXE BCE_0583 ENOG4105BZ1 (ABC) transporter BCE_0584 ENOG4107NBY Membrane BCE_0585 ENOG4105CBC glutamate synthase BCE_0587 ENOG4108IUW ABC transporter BCE_0591 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCE_0592 ENOG4105G5W regulator Fur family BCE_0597 ENOG4108JQC penicillin-binding protein 1A BCE_0598 ENOG4107ZQN disulfide bond BCE_0600 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCE_0602 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCE_0603 ENOG4105BZU Histidine kinase BCE_0605 ENOG4105CYN Serine protein kinase BCE_0609 ENOG4105CT1 (ABC) transporter BCE_0610 ENOG4105CDA abc transporter atp-binding protein BCE_0611 ENOG4105DRP amino acid AbC transporter BCE_0614 ENOG4105C94 Transporter BCE_0618 ENOG4105DZ6 Band 7 protein BCE_0620 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCE_0621 ENOG4108V9W transcriptional regulatory protein BCE_0622 ENOG4105D4T Citrate transporter BCE_0628 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCE_0629 ENOG4108IJ9 (ABC) transporter BCE_0630 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCE_0631 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCE_0632 ENOG4105BZ7 extracellular solute-binding protein family 1 BCE_0633 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCE_0634 ENOG4108STX response regulator BCE_0635 ENOG4105US7 Histidine kinase BCE_0640 ENOG4108MRH transcriptional regulatory protein BCE_0642 ENOG4105C6K Malic enzyme BCE_0645 ENOG4108UZ3 Transporter BCE_0646 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE_0649 ENOG4105BZU Histidine kinase BCE_0650 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_0653 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCE_0654 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCE_0655 ENOG4108JB9 formate dehydrogenase BCE_0660 ENOG4105CUB amino acid BCE_0663 ENOG4105C59 p-type ATPase BCE_0664 ENOG4105DAP Nicotinate phosphoribosyltransferase BCE_0672 ENOG41073R8 VanW family BCE_0673 ENOG4108KGH TRANSCRIPTIONal BCE_0674 ENOG4105D9N nucleoside BCE_0675 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCE_0676 ENOG4105C37 (CBS) domain BCE_0677 ENOG4108IJ0 Aspartate ammonia-lyase BCE_0678 ENOG4105DAA L-lactate BCE_0682 ENOG4105DUX Transporter BCE_0683 ENOG4108MES Periplasmic binding protein BCE_0684 ENOG4105DQ5 transport system permease protein BCE_0685 ENOG4108IHU transport system permease protein BCE_0686 ENOG4105E0A ABC, transporter BCE_0687 ENOG4105DMQ Methyltransferase BCE_0689 ENOG4105EXW epimerase dehydratase BCE_0690 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BCE_0692 ENOG4107T89 von Willebrand factor, type A BCE_0693 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCE_0694 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCE_0696 ENOG4105BZU Histidine kinase BCE_0697 ENOG4105D5Q Arginine ornithine antiporter BCE_0698 ENOG4107414 GntR family transcriptional regulator BCE_0699 ENOG4105C5Y PTS System BCE_0700 ENOG4105CG3 alpha amylase, catalytic region BCE_0703 ENOG4105E1K spore germination protein BCE_0705 ENOG4105CRN Aminoglycoside phosphotransferase BCE_0706 ENOG4105BZG amino acid carrier protein BCE_0707 ENOG4105CDA abc transporter atp-binding protein BCE_0708 ENOG4105CT1 (ABC) transporter BCE_0709 ENOG4105EAD ABC transporter BCE_0710 ENOG4105DRP amino acid AbC transporter BCE_0711 ENOG4108IQI permease BCE_0716 ENOG4105D29 Helix-turn-helix type 11 domain protein BCE_0717 ENOG4105NAE bifunctional deaminase-reductase domain protein BCE_0718 ENOG4105BZU Histidine kinase BCE_0721 ENOG4105CHH sulfate transporter BCE_0722 ENOG41068KF Universal stress protein BCE_0724 ENOG4105DEF Extracellular solute-binding protein, family 5 BCE_0726 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE_0727 ENOG4108JQ7 (ABC) transporter BCE_0729 ENOG4105CXY transporter BCE_0730 ENOG41067TZ transcriptional regulator, MarR family BCE_0731 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_0732 ENOG4105ETE Transcriptional regulator (LacI family BCE_0733 ENOG4108RVA ribokinase BCE_0736 ENOG4105CNN ABC, transporter BCE_0737 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCE_0738 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCE_0751 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE_0752 ENOG41069ER domain protein BCE_0753 ENOG4105VZ8 Transcriptional regulator BCE_0754 ENOG4107D63 BCE_0757 ENOG4105DUX Transporter BCE_0762 ENOG4105C85 amino acid BCE_0763 ENOG4105C7N Xanthine uracil vitamin C permease BCE_0766 ENOG4105MA6 gCN5-related N-acetyltransferase BCE_0771 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCE_0772 ENOG4105E2S oxidase) subunit II BCE_0776 ENOG4106CAD Protein of unknown function (DUF3311) BCE_0777 ENOG4105E1V na solute symporter BCE_0780 ENOG4108NHD germination protein BCE_0783 ENOG4105CE1 Ferrous iron transport protein b BCE_0784 ENOG4105CVA phosphate BCE_0785 ENOG4105C8U phosphate abc transporter BCE_0786 ENOG4105E2Z phosphate ABC transporter (Permease BCE_0791 ENOG41080XQ Signal transduction protein with cbs domains BCE_0795 ENOG4105ETU transcriptional activator (TenA BCE_0797 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCE_0799 ENOG4108VEU Thiamine monophosphate synthase BCE_0800 ENOG41080HI glycine oxidase BCE_0803 ENOG4105D06 uba thif-type nad fad binding protein BCE_0804 ENOG4105DWF phosphomethylpyrimidine kinase BCE_0814 ENOG4108INS Transcriptional regulator BCE_0817 ENOG4105C7N Xanthine uracil vitamin C permease BCE_0819 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCE_0826 ENOG4108B31 Spore germination protein BCE_0831 ENOG4107Y03 Nitroreductase BCE_0832 ENOG4105ED1 spovr family BCE_0840 ENOG4107SCJ type I restriction enzyme EcoKI subunit R BCE_0844 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCE_0845 ENOG4107Y5K Resolvase BCE_0853 ENOG4105ED1 spovr family BCE_0855 ENOG4107UNZ domain protein BCE_0858 ENOG4105ED1 spovr family BCE_0860 ENOG4108TCS Glutamyl endopeptidase BCE_0865 ENOG4105XTG Pfam:DUF156 BCE_0866 ENOG4105VFE sira family BCE_0867 ENOG4107TPS domain protein BCE_0868 ENOG4105VFE sira family BCE_0869 ENOG41085GJ domain protein BCE_0871 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCE_0872 ENOG41087NI Sulfite exporter TauE/SafE BCE_0875 ENOG4108KGH TRANSCRIPTIONal BCE_0881 ENOG4105EMD TRANSCRIPTIONal BCE_0882 ENOG4105VCP PTS System BCE_0883 ENOG4105VZJ PTS System BCE_0887 ENOG41069ER domain protein BCE_0888 ENOG4107RBB ABC transporter, permease BCE_0889 ENOG4105C19 ABC transporter BCE_0895 ENOG4105WEF catalase BCE_0902 ENOG4107T5V SNARE associated Golgi BCE_0909 ENOG4105CUB amino acid BCE_0910 ENOG4107RWR Sodium hydrogen exchanger BCE_0912 ENOG4106KNT transcriptional regulator BCE_0920 ENOG4108YXU transcriptional regulator AsnC family BCE_0922 ENOG4105UBK short-chain dehydrogenase reductase BCE_0925 ENOG4105KPY Small multidrug resistance protein BCE_0926 ENOG4105KPY Small multidrug resistance protein BCE_0931 ENOG4105NF4 modulator of drug activity BCE_0932 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCE_0933 ENOG4105E5W Transporter BCE_0935 ENOG4107RKG DJ-1/PfpI family BCE_0937 ENOG4105D5Q Arginine ornithine antiporter BCE_0940 ENOG4105C26 Dehydrogenase BCE_0942 ENOG4105BZ1 (ABC) transporter BCE_0943 ENOG4105BZ1 (ABC) transporter BCE_0946 ENOG4105DRP amino acid AbC transporter BCE_0947 ENOG4105CDA abc transporter atp-binding protein BCE_0950 ENOG410839P BCE_0957 ENOG4107FQX Alpha-acetolactate decarboxylase BCE_0961 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein BCE_0962 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE_0964 ENOG4105D4P Coproporphyrinogen iii oxidase BCE_0968 ENOG4105CHH sulfate transporter BCE_0973 ENOG4106AKK s-layer domain-containing protein BCE_0973 ENOG4106AKK s-layer domain-containing protein BCE_0975 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE_0976 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE_0979 ENOG4105CGU Enoyl-CoA hydratase BCE_0983 ENOG4105DER m42 family BCE_0986 ENOG4108FPN Integrase BCE_0989 ENOG4105G7B Protein of unknown function (DUF2992) BCE_0990 ENOG41086D8 Transcriptional regulator BCE_0991 ENOG4108ZJ4 polysaccharide deacetylase BCE_1002 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE_1004 ENOG4108JQ7 (ABC) transporter BCE_1008 ENOG4105CSH Transporter BCE_1010 ENOG4108MRH transcriptional regulatory protein BCE_1018 ENOG4107QMH DNA methylase BCE_1026 ENOG4105FA0 parb-like partition protein BCE_1028 ENOG4105CDU Replicative dna helicase BCE_1034 ENOG41087YS Phage shock protein A BCE_1046 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCE_1052 ENOG4105CMT Dihydroxyacetone kinase BCE_1054 ENOG4105CMT Dihydroxyacetone kinase BCE_1056 ENOG410780I phosphoprotein phosphatase activity BCE_1067 ENOG4105FBW Monooxygenase BCE_1071 ENOG410847I Transcriptional regulator, BadM Rrf2 family BCE_1084 ENOG4105WN5 stage II sporulation protein BCE_1086 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_1088 ENOG4108MJI response regulator BCE_1089 ENOG4105BZU Histidine kinase BCE_1090 ENOG4105BZU Histidine kinase BCE_1098 ENOG4105D7V transposase BCE_1101 ENOG4105ENE Histidine kinase BCE_1102 ENOG4108VB1 regulatoR BCE_1109 ENOG4107VRP DNA repair exonuclease BCE_1110 ENOG4106D4I domain protein BCE_1118 ENOG4105DU6 RNA polymerase BCE_1120 ENOG4108MUZ hydrolase BCE_1123 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCE_1126 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCE_1127 ENOG4105IYK transposase BCE_1128 ENOG4105DQ6 Transposase BCE_1131 ENOG4105EMN RNA polymerase sigma factor BCE_1135 ENOG4105EEM helicase BCE_1142 ENOG4105CFG Acts as a chaperone (By similarity) BCE_1144 ENOG4106F1P AAA ATPase, central domain protein BCE_1145 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE_1151 ENOG4105K59 histidine triad (HIT) protein BCE_1158 ENOG410905X membrane-flanked domain protein BCE_1159 ENOG4105CKV Membrane BCE_1163 ENOG410905X membrane-flanked domain protein BCE_1164 ENOG4105CKV Membrane BCE_1165 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCE_1166 ENOG4105BZ4 penicillin-binding protein BCE_1169 ENOG4105C1Q protoporphyrinogen oxidase BCE_1175 ENOG4105NA0 Transcriptional regulator BCE_1178 ENOG4105ECB domain protein BCE_1184 ENOG4106DF1 BCE_1185 ENOG4105D29 Helix-turn-helix type 11 domain protein BCE_1187 ENOG4106AXD BCE_1188 ENOG4108RQ5 Beta-lactamase domain-containing protein BCE_1189 ENOG4105DF9 Lipoate-protein, ligase BCE_1193 ENOG4105CEY Amp-dependent synthetase and ligase BCE_1196 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BCE_1197 ENOG4108I5D sulfate abc transporter BCE_1198 ENOG4105ECW sulfate abc transporter BCE_1204 ENOG4105CNA YD repeat protein BCE_1209 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BCE_1211 ENOG4105ENX hydrolase BCE_1212 ENOG4107RN3 metallophosphoesterase BCE_1213 ENOG4107TVP HD domain protein BCE_1215 ENOG4108AEY RNA polymerase sigma factor BCE_1216 ENOG41086D8 Transcriptional regulator BCE_1218 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE_1223 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCE_1227 ENOG4105ZU5 s-layer protein BCE_1228 ENOG4107QP3 malate synthase g BCE_1232 ENOG4105VEQ Cold shock protein BCE_1236 ENOG4105XVF Competence transcription factor BCE_1254 ENOG4105ERH Fumarylacetoacetate hydrolase BCE_1259 ENOG4105CAQ asparagine synthetase BCE_1261 ENOG4105CH6 catalase BCE_1269 ENOG4105BZU Histidine kinase BCE_1274 ENOG4105QNR S1 RNA binding domain protein BCE_1275 ENOG4105CNA YD repeat protein BCE_1280 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE_1282 ENOG4107AYK membrAne BCE_1283 ENOG41073B9 BCE_1285 ENOG4108KP7 hydrolase BCE_1293 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCE_1294 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCE_1297 ENOG4105C31 Tryptophanyl-tRNA synthetase BCE_1301 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE_1302 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE_1304 ENOG4108JQ7 (ABC) transporter BCE_1305 ENOG4105UQX Mate efflux family protein BCE_1310 ENOG4108ZCF integral membrane protein BCE_1312 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCE_1314 ENOG4105DPN Oligoendopeptidase f BCE_1317 ENOG4108Z18 K06886 hemoglobin BCE_1318 ENOG4105MIX Adenylate cyclase BCE_1319 ENOG4106EFP UPF0738 protein BCE_1322 ENOG4105EMS pseudouridine synthase BCE_1326 ENOG4105K64 Glycosyl transferase, family 2 BCE_1331 ENOG4107TVC Glycosyl transferase, family 2 BCE_1335 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCE_1336 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCE_1338 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCE_1353 ENOG4105CK7 Sodium proline symporter BCE_1356 ENOG4105CRQ synthase (Component I) BCE_1357 ENOG4105DDQ anthranilate synthase BCE_1375 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCE_1379 ENOG4105C7S Dehydrogenase BCE_1381 ENOG4105VZ8 Transcriptional regulator BCE_1388 ENOG4105DZ1 carboxypeptidase BCE_1389 ENOG4105VFR signal peptidase BCE_1397 ENOG4105C26 Dehydrogenase BCE_1399 ENOG4105F38 ABC transporter, permease BCE_1400 ENOG4105D38 putrescine abc transporter BCE_1401 ENOG4107RUE extracellular solute-binding protein family 1 BCE_1403 ENOG4105EYF MMPL domain protein BCE_1405 ENOG4108YBP pseudouridine synthase BCE_1407 ENOG4105K4I Scp-like extracellular BCE_1409 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCE_1410 ENOG4105CQB FAD linked oxidase domain protein BCE_1413 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_1414 ENOG4105BZU Histidine kinase BCE_1415 ENOG4105JXH GntR family transcriptional regulator BCE_1419 ENOG4106A3R peptidase BCE_1421 ENOG4108QTI )-transporter BCE_1422 ENOG4107TS3 membrane protein, TerC BCE_1423 ENOG4105CZN Potassium uptake protein BCE_1424 ENOG410681C small acid-soluble spore protein BCE_1425 ENOG4108Z7G MaoC domain protein dehydratase BCE_1429 ENOG4105CHR reductase BCE_1436 ENOG4105C4Y ABC transporter BCE_1437 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCE_1438 ENOG4107RCV ABC transporter, permease BCE_1442 ENOG4105E98 transcriptional regulator DeoR family BCE_1445 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCE_1447 ENOG4105PXI polysaccharide deacetylase BCE_1449 ENOG4105BZU Histidine kinase BCE_1450 ENOG41090MY MarR family Transcriptional regulator BCE_1453 ENOG4106DF1 BCE_1455 ENOG4105BZU Histidine kinase BCE_1459 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCE_1460 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCE_1469 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCE_1471 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCE_1472 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCE_1473 ENOG4105CZV ABC transporter BCE_1475 ENOG4105CJ1 ABC, transporter BCE_1482 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCE_1483 ENOG4105EA8 2-Nitropropane dioxygenase BCE_1484 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCE_1486 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE_1492 ENOG4105NQC Flavodoxin BCE_1509 ENOG4105CZN Potassium uptake protein BCE_1510 ENOG41063Y9 BCE_1511 ENOG4105KBJ sporulation protein ytfj BCE_1516 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCE_1517 ENOG4105C7K acetolactate synthase BCE_1518 ENOG4108ZP8 Acetolactate synthase small subunit BCE_1533 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCE_1536 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCE_1538 ENOG4105E0M Sulfatase BCE_1542 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCE_1546 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCE_1547 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCE_1549 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCE_1550 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCE_1551 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCE_1552 ENOG4105C8J )-transporter BCE_1557 ENOG4105DFD Na H antiporter BCE_1562 ENOG4105ENE Histidine kinase BCE_1563 ENOG4105WH1 Two component transcriptional regulator luxr family BCE_1567 ENOG41089UC methyltransferase, type 11 BCE_1576 ENOG4105CJ3 phosphate transporter BCE_1577 ENOG4107GRR phosphate transport regulator BCE_1578 ENOG4105BZ4 penicillin-binding protein BCE_1583 ENOG4105BZU Histidine kinase BCE_1584 ENOG4105I3N Conserved Protein BCE_1587 ENOG4105BZU Histidine kinase BCE_1593 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE_1594 ENOG4105DZ1 carboxypeptidase BCE_1595 ENOG4108JIC nucleoside recognition domain protein BCE_1597 ENOG4105FE9 pseudouridine synthase BCE_1599 ENOG4107TWT Cytochrome c biogenesis protein BCE_1600 ENOG4105CRE cytochrome C BCE_1601 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_1602 ENOG4105BZU Histidine kinase BCE_1603 ENOG4108WBT adenosyltransferase BCE_1604 ENOG41063SB peptidase BCE_1606 ENOG4108SAX Membrane BCE_1609 ENOG4105C9U ATP-dependent DNA helicase RecQ BCE_1610 ENOG4105C9U ATP-dependent DNA helicase RecQ BCE_1611 ENOG4105I7S Abortive infection protein BCE_1613 ENOG4107RGJ metallophosphoesterase BCE_1614 ENOG4108XDN Transcriptional regulator BCE_1616 ENOG4108S6Z Negative regulator of genetic competence BCE_1621 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCE_1622 ENOG4105HDK L-asparaginase BCE_1629 ENOG4105S2F BCE_1630 ENOG41065D1 BCE_1636 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCE_1639 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCE_1641 ENOG4105EAH synthase BCE_1646 ENOG41068YB TPR repeat-containing protein BCE_1649 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCE_1650 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCE_1658 ENOG4108JYZ YitT family BCE_1660 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCE_1663 ENOG4105FJR Lmbe family BCE_1664 ENOG4105CPK Glycosyl transferase (Group 1 BCE_1671 ENOG4105DVT helicase BCE_1672 ENOG4105YAC BCE_1676 ENOG4105CSM endonuclease III BCE_1678 ENOG4105BZ4 penicillin-binding protein BCE_1690 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCE_1692 ENOG4105DVT helicase BCE_1693 ENOG4105CTD carboxy-peptidase BCE_1695 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCE_1698 ENOG4105C2W permease BCE_1699 ENOG4105DHF Membrane BCE_1701 ENOG410890F Dynamin family BCE_1703 ENOG4108W0I acetyltransferase BCE_1705 ENOG4105KHC sulfurtransferase BCE_1710 ENOG4108SZE gCN5-related N-acetyltransferase BCE_1714 ENOG41081VK Ribonuclease BCE_1727 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE_1729 ENOG4107RWR Sodium hydrogen exchanger BCE_1730 ENOG4105CN5 Metallo-Beta-Lactamase BCE_1731 ENOG4108Z5V transcriptional regulator, merr family BCE_1733 ENOG4105H67 Protein of unknown function (DUF421) BCE_1734 ENOG41080C8 DUF218 domain BCE_1738 ENOG4107Y80 Major Facilitator superfamily BCE_1744 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCE_1746 ENOG4107R0U MotA TolQ exbB proton channel BCE_1747 ENOG4105ER2 Ompa motb domain protein BCE_1748 ENOG4107YTP response regulator receiver protein BCE_1749 ENOG4105CBS Chea signal transduction histidine kinase BCE_1750 ENOG4105DD5 Flagellar motor switch protein BCE_1754 ENOG4105BZU Histidine kinase BCE_1758 ENOG4105E1Q flagellar hook-associated protein BCE_1759 ENOG4105DTJ flagellar hook-associated protein BCE_1760 ENOG4107TPX flagellar hook-associated BCE_1763 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCE_1764 ENOG4108ZC9 flagellar basal-body rod protein flgc BCE_1765 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCE_1766 ENOG4107U2N Flagellar M-ring protein BCE_1767 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCE_1773 ENOG4105BZE flagellar hook protein, FlgE BCE_1777 ENOG4107R88 Chemotaxis protein (CheV) BCE_1779 ENOG4105I03 Flagellin BCE_1780 ENOG4105I03 Flagellin BCE_1781 ENOG4105E4C Lytic transglycosylase catalytic BCE_1783 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCE_1784 ENOG4105DD5 Flagellar motor switch protein BCE_1786 ENOG4105CN7 Flagellar biosynthetic protein FliP BCE_1787 ENOG4105VS8 Flagellar biosynthetic protein fliq BCE_1790 ENOG4105D7B Flagellar biosynthesis protein flha BCE_1791 ENOG4105FZW flagellar biosynthesis regulator FlhF BCE_1792 ENOG4105KTQ flagellar basal-body rod protein BCE_1793 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCE_1798 ENOG4108RZE Tetr family transcriptional regulator BCE_1802 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCE_1805 ENOG4108U4N (sortase) family BCE_1810 ENOG4105DUM transcriptional regulator, lysR family BCE_1811 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCE_1813 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCE_1814 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BCE_1817 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BCE_1822 ENOG4105CVJ phosphoglycerate mutase BCE_1828 ENOG4105CAQ asparagine synthetase BCE_1832 ENOG4105PGM cation diffusion facilitator family transporter BCE_1834 ENOG4105DRR Transcriptional regulator, GntR family BCE_1835 ENOG4108UZ3 Transporter BCE_1836 ENOG4105CKI cobalamin synthesis protein BCE_1837 ENOG4108PJD permease BCE_1840 ENOG4105DFD Na H antiporter BCE_1841 ENOG4105C9Q fumarate hydratase class II BCE_1846 ENOG4107QJQ Mate efflux family protein BCE_1847 ENOG4105EC3 peptidase S51, dipeptidase E BCE_1856 ENOG4106BRA Membrane BCE_1865 ENOG4105CJ1 ABC, transporter BCE_1870 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCE_1872 ENOG4108IJ0 Aspartate ammonia-lyase BCE_1873 ENOG4105C6K Malic enzyme BCE_1877 ENOG4105C0D helicase BCE_1881 ENOG41067QW Transcriptional regulator BCE_1887 ENOG4105FVX BCE_1900 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCE_1901 ENOG4105DRS transport system, permease BCE_1903 ENOG4108X79 transcriptional regulator BCE_1904 ENOG4105E70 isomerase BCE_1905 ENOG4105CE4 GlcNAc 6-P deacetylase BCE_1907 ENOG4105DE4 1-phosphofructokinase BCE_1909 ENOG4105CSR polyphosphate kinase 2 BCE_1910 ENOG4105U3E Transcriptional regulator BCE_1913 ENOG4105DXI Major Facilitator superfamily BCE_1916 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCE_1918 ENOG4105EU0 Major facilitator Superfamily BCE_1919 ENOG4105C6T cysteine synthase BCE_1923 ENOG4105C8J )-transporter BCE_1925 ENOG4105X5K response regulator receiver protein BCE_1926 ENOG4105H67 Protein of unknown function (DUF421) BCE_1931 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCE_1932 ENOG4105CHR reductase BCE_1933 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCE_1934 ENOG4105C7K acetolactate synthase BCE_1938 ENOG4105C7B Threonine dehydratase BCE_1943 ENOG4105C6X Major Facilitator BCE_1944 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCE_1947 ENOG4105DY9 regulatoR BCE_1948 ENOG4105CYC Transferase BCE_1953 ENOG4105F6J Alpha beta hydrolase fold BCE_1955 ENOG41068WN BCE_1960 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCE_1964 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCE_1966 ENOG4105C0X amino acid BCE_1974 ENOG4107RHR regulatoR BCE_1976 ENOG4105D9N nucleoside BCE_1977 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCE_1982 ENOG4107RAQ aminopeptidase BCE_1986 ENOG4105U5Y Transcriptional regulator BCE_1987 ENOG4105CIG ABC transporter BCE_1988 ENOG4105CIG ABC transporter BCE_1997 ENOG4108T5E Copper resistance protein BCE_1998 ENOG4105KTB nuclear export factor GLE1 BCE_1999 ENOG4107RT3 EamA-like transporter family BCE_2000 ENOG4105GZI Transcriptional regulator BCE_2001 ENOG4108Z40 Transcriptional regulator BCE_2002 ENOG4107ZXU DSBA oxidoreductase BCE_2003 ENOG4108TVJ Nitroreductase BCE_2006 ENOG4106F5Q Membrane BCE_2007 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCE_2009 ENOG4105CKI cobalamin synthesis protein BCE_2011 ENOG4105C0Z ABC transporter BCE_2012 ENOG4108IV0 ABC, transporter BCE_2013 ENOG4105C32 Amino acid ABC transporter (Permease) BCE_2015 ENOG4105SKE transcriptional Regulator LysR family BCE_2017 ENOG4105MDS 4-oxalocrotonate tautomerase BCE_2021 ENOG4105C4M (Ubiquinol oxidase) subunit I BCE_2022 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCE_2023 ENOG4108JJ9 ABC, transporter BCE_2024 ENOG4108JJ8 (ABC) transporter BCE_2026 ENOG4105K64 Glycosyl transferase, family 2 BCE_2028 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCE_2040 ENOG4105BZ1 (ABC) transporter BCE_2041 ENOG4105EFI regulatoR BCE_2042 ENOG4105BZU Histidine kinase BCE_2045 ENOG4108VQJ O-methyltransferase BCE_2046 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCE_2047 ENOG4108ZJ4 polysaccharide deacetylase BCE_2049 ENOG41081VB Hydrolase BCE_2051 ENOG4105D6E homoserine dehydrogenase BCE_2056 ENOG4108KGH TRANSCRIPTIONal BCE_2059 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE_2060 ENOG4105BZU Histidine kinase BCE_2061 ENOG4107VMI polysaccharide deacetylase BCE_2063 ENOG4105KT7 mgtC SapB transporter BCE_2064 ENOG4105VRR gCN5-related N-acetyltransferase BCE_2065 ENOG4105YWU small acid-soluble spore protein BCE_2067 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCE_2077 ENOG4105KRN Transcriptional regulator, abrb family BCE_2079 ENOG4105YVS arsR family transcriptional regulator BCE_2080 ENOG4105CPC Aldo Keto reductase BCE_2081 ENOG4107XZQ multidrug resistance protein BCE_2091 ENOG4108K88 Membrane BCE_2092 ENOG4108WPJ Ferritin-like domain BCE_2096 ENOG4105DEN Luciferase family BCE_2099 ENOG4105VMI -acetyltransferase BCE_2100 ENOG4107QM2 Aldo Keto reductase BCE_2101 ENOG4105CKI cobalamin synthesis protein BCE_2103 ENOG4105DSE periplasmic solute binding protein BCE_2105 ENOG4105K4T epimerase BCE_2107 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCE_2113 ENOG4105CVJ phosphoglycerate mutase BCE_2117 ENOG4107T5V SNARE associated Golgi BCE_2120 ENOG4108PJD permease BCE_2122 ENOG4108S4H thioesterase Superfamily protein BCE_2127 ENOG4105SXS Protein of unknown function (DUF456) BCE_2128 ENOG4105C37 (CBS) domain BCE_2135 ENOG4108Z7R Chaperone CsaA BCE_2139 ENOG4108ZRV stage ii sporulation protein p BCE_2141 ENOG4108VXD carboxy-peptidase BCE_2143 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCE_2148 ENOG4105EFA 4-hydroxyphenylacetate BCE_2150 ENOG4105U1N riboflavin BCE_2153 ENOG4105KME endoribonuclease L-psp BCE_2159 ENOG41069HH 4-oxalocrotonate tautomerase BCE_2161 ENOG4108X4Q Hydrolase BCE_2163 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCE_2164 ENOG4107RBS Methyltransferase BCE_2168 ENOG41087PP glycosyltransferase MGT family BCE_2169 ENOG4108JYZ YitT family BCE_2170 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE_2176 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCE_2181 ENOG4105KBJ sporulation protein ytfj BCE_2186 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCE_2192 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCE_2194 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCE_2195 ENOG4105EMN RNA polymerase sigma factor BCE_2198 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BCE_2202 ENOG4108V06 Glutathione peroxidase BCE_2205 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE_2211 ENOG4105CMG Carbohydrate kinase BCE_2212 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BCE_2214 ENOG4107QNK )-transporter BCE_2222 ENOG4105MCT stage V sporulation protein S BCE_2225 ENOG4105C5H ABC transporter BCE_2228 ENOG4108UUM single-stranded DNA-binding protein BCE_2234 ENOG4107YX5 Pfam:DUF548 BCE_2236 ENOG4105C75 arginyL-tRNA synthetase BCE_2244 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCE_2246 ENOG4105C8J )-transporter BCE_2250 ENOG4107XGZ Hydrolase BCE_2251 ENOG4105CY2 Citrate transporter BCE_2252 ENOG4105C0A alcohol dehydrogenase BCE_2255 ENOG4105KD7 acetyltransferase BCE_2256 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCE_2262 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCE_2264 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCE_2268 ENOG4107RVG penicillin-binding protein BCE_2270 ENOG4105E9Q Acyl-transferase BCE_2271 ENOG4108UT2 hemolysin iii BCE_2273 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCE_2276 ENOG4108RCR degv family BCE_2277 ENOG4105E8R UPF0173 metal-dependent hydrolase BCE_2278 ENOG4108KF3 Electron transport protein SCO1 SenC BCE_2279 ENOG4107Y70 Heat shock protein BCE_2280 ENOG4105CAQ asparagine synthetase BCE_2283 ENOG4108MES Periplasmic binding protein BCE_2285 ENOG4105F0I Aminotransferase BCE_2290 ENOG4107Y70 Heat shock protein BCE_2291 ENOG4105D8X mechanosensitive ion channel BCE_2292 ENOG4105BZU Histidine kinase BCE_2293 ENOG4105WH1 Two component transcriptional regulator luxr family BCE_2294 ENOG4105FQP Beta-lactamase BCE_2295 ENOG4106KNT transcriptional regulator BCE_2302 ENOG4105CMG Carbohydrate kinase BCE_2303 ENOG4105C6Z Gluconate BCE_2305 ENOG4108YV3 Protein of unknown function (DUF2711) BCE_2313 ENOG4108IJ8 ABC transporter BCE_2314 ENOG4105E90 ABC transporter BCE_2328 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE_2331 ENOG4107S4Y M20 DapE family protein YgeY BCE_2332 ENOG4108TSC N-acetyltransferase BCE_2333 ENOG4108JUB Transcriptional regulator BCE_2334 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCE_2342 ENOG410841Q phosphoesterase PA-phosphatase related protein BCE_2344 ENOG4105SZ6 Thioredoxin BCE_2359 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE_2370 ENOG4105BZ4 penicillin-binding protein BCE_2372 ENOG4105CZM Major Facilitator BCE_2373 ENOG4105W8X HesB YadR YfhF-family protein BCE_2377 ENOG4105DXD 2-methylcitrate dehydratase BCE_2378 ENOG4105CR4 methylisocitrate lyase BCE_2380 ENOG4105C1G acyl-Coa dehydrogenase BCE_2381 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCE_2383 ENOG4105N14 lysine exporter protein LysE YggA BCE_2384 ENOG4105E39 Enoyl-CoA hydratase BCE_2390 ENOG4107RFY SbcCD D subunit BCE_2396 ENOG4105FCD Major Facilitator BCE_2398 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCE_2399 ENOG4105E4F Isochorismate synthase BCE_2400 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCE_2401 ENOG4105WQI isochorismatase BCE_2402 ENOG4105CEY Amp-dependent synthetase and ligase BCE_2403 ENOG4105WQT MbtH domain protein BCE_2404 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_2407 ENOG4105K70 DNA-binding protein BCE_2411 ENOG4105BZG amino acid carrier protein BCE_2417 ENOG4105FE9 pseudouridine synthase BCE_2419 ENOG4105C22 threonyL-tRNA synthetase BCE_2420 ENOG4105C19 ABC transporter BCE_2422 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCE_2428 ENOG4108D32 Methyltransferase BCE_2435 ENOG41081I9 integral membrane protein BCE_2438 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCE_2440 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCE_2442 ENOG4105EYF MMPL domain protein BCE_2447 ENOG4105WCN acetyltransferase BCE_2450 ENOG4105C1Q protoporphyrinogen oxidase BCE_2452 ENOG41068WN BCE_2454 ENOG4105VEQ Cold shock protein BCE_2460 ENOG410667J hydrolase BCE_2463 ENOG4105F27 Major Facilitator BCE_2464 ENOG4107V2S Transcriptional regulator BCE_2465 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCE_2469 ENOG4105DND Transcriptional regulator BCE_2471 ENOG4108RPX mosc domain containing protein BCE_2474 ENOG4105BZ1 (ABC) transporter BCE_2475 ENOG4105BZ1 (ABC) transporter BCE_2481 ENOG4108JCI Transcriptional regulator BCE_2494 ENOG4105F32 YngK protein BCE_2499 ENOG4105RD7 BadF BadG BcrA BcrD BCE_2509 ENOG4105C1J atp-dependent rna helicase BCE_2510 ENOG4108RZE Tetr family transcriptional regulator BCE_2513 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCE_2514 ENOG41088CC tellurite resistance protein tehB BCE_2516 ENOG4108I0C methyltransferase BCE_2517 ENOG4107RA9 decarboxylase BCE_2518 ENOG4105K56 Transcriptional regulator BCE_2527 ENOG4105CIN aminoacyl-histidine dipeptidase BCE_2533 ENOG4107RVG penicillin-binding protein BCE_2536 ENOG4107RF6 penicillin-binding protein BCE_2538 ENOG4107RF6 penicillin-binding protein BCE_2541 ENOG4107RGJ metallophosphoesterase BCE_2543 ENOG4105CJ1 ABC, transporter BCE_2545 ENOG4107Z3H Transcriptional regulator, TetR family BCE_2548 ENOG4105C1G acyl-Coa dehydrogenase BCE_2549 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCE_2550 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCE_2551 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCE_2552 ENOG4105E39 Enoyl-CoA hydratase BCE_2553 ENOG4107QX3 carboxylase BCE_2554 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCE_2558 ENOG4105DBI uridine monophosphokinase BCE_2565 ENOG4105T9C HD domain BCE_2567 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCE_2568 ENOG4108RYK Nad-dependent epimerase dehydratase BCE_2576 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCE_2579 ENOG4105FQP Beta-lactamase BCE_2582 ENOG4107Y80 Major Facilitator superfamily BCE_2585 ENOG41089UC methyltransferase, type 11 BCE_2601 ENOG4105EFA 4-hydroxyphenylacetate BCE_2604 ENOG4105CPQ Dehydrogenase BCE_2607 ENOG410900G Protein of unknown function (DUF421) BCE_2608 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCE_2609 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCE_2611 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BCE_2626 ENOG4105D6E homoserine dehydrogenase BCE_2629 ENOG4105ETU transcriptional activator (TenA BCE_2638 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCE_2661 ENOG410667J hydrolase BCE_2662 ENOG4105BZU Histidine kinase BCE_2663 ENOG4107RF6 penicillin-binding protein BCE_2671 ENOG4108HGU Histidine kinase BCE_2673 ENOG4105RHY Pfam:UPF0157 BCE_2675 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_2676 ENOG4105GR3 Histidine kinase BCE_2677 ENOG4105CB2 alcohol dehydrogenase BCE_2678 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCE_2679 ENOG4105CJN penicillin-binding protein BCE_2680 ENOG4108IG5 Transcriptional regulator BCE_2681 ENOG4105CHR reductase BCE_2690 ENOG4108V4B ThiJ pfpI BCE_2691 ENOG4105CVK Glutamate decarboxylase BCE_2694 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BCE_2699 ENOG4107Y80 Major Facilitator superfamily BCE_2703 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCE_2709 ENOG4107Y9U Membrane BCE_2718 ENOG4105FCD Major Facilitator BCE_2719 ENOG4105E09 nadh pyrophosphatase BCE_2720 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCE_2721 ENOG4108Z4K mutator MutT protein BCE_2727 ENOG4108XI2 Domain of unknown function (DUF1963) BCE_2734 ENOG4105PKS Excinuclease abc c subunit domain protein BCE_2742 ENOG4107VFR oxidoreductase BCE_2744 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCE_2747 ENOG4105PAD Hydrolase BCE_2749 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_2750 ENOG4105BZU Histidine kinase BCE_2758 ENOG4107WD8 ABC transporter, permease BCE_2761 ENOG4108IUM Glycogen debranching enzyme BCE_2765 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCE_2766 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCE_2768 ENOG4105FDR Membrane BCE_2769 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE_2770 ENOG4105CIS alcohol dehydrogenase BCE_2780 ENOG4105MSI germination protein ypeb BCE_2794 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCE_2797 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE_2798 ENOG4105E98 transcriptional regulator DeoR family BCE_2802 ENOG4107QKR Dehydrogenase BCE_2804 ENOG4107RUY (E1 component), alpha subunit BCE_2806 ENOG4105E1F short-chain dehydrogenase reductase BCE_2807 ENOG4105RHY Pfam:UPF0157 BCE_2810 ENOG4105E09 nadh pyrophosphatase BCE_2815 ENOG4107SQ8 Glycine betaine BCE_2816 ENOG4108IJ7 Glycine betaine BCE_2823 ENOG41082BV acetyltransferase BCE_2824 ENOG4108M1A Chitin-binding protein BCE_2825 ENOG41087PP glycosyltransferase MGT family BCE_2830 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE_2831 ENOG4105MSB protein, conserved in bacteria BCE_2837 ENOG4108Z7F N-acetyltransferase BCE_2839 ENOG4105EEM helicase BCE_2842 ENOG4105C9U ATP-dependent DNA helicase RecQ BCE_2855 ENOG4108M1A Chitin-binding protein BCE_2859 ENOG4105BZG amino acid carrier protein BCE_2860 ENOG4105C26 Dehydrogenase BCE_2861 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCE_2862 ENOG4105CTU Proline racemase BCE_2863 ENOG4105CTU Proline racemase BCE_2866 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCE_2872 ENOG4107T5V SNARE associated Golgi BCE_2875 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCE_2876 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BCE_2879 ENOG4105DTQ mandelate racemase muconate lactonizing BCE_2891 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCE_2892 ENOG4105BZU Histidine kinase BCE_2893 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_2897 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCE_2902 ENOG4105DPN Oligoendopeptidase f BCE_2904 ENOG4105DVH amino acid BCE_2906 ENOG4105EPR degv family BCE_2920 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCE_2921 ENOG4106K7D Major facilitator family transporter BCE_2926 ENOG4107BMA Transglycosylase associated protein BCE_2929 ENOG41089UC methyltransferase, type 11 BCE_2938 ENOG4105CHM Aminotransferase BCE_2941 ENOG4108ZMI UPF0477 protein BCE_2944 ENOG4105DVE abc transporter atp-binding protein BCE_2955 ENOG4105C02 permease BCE_2958 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCE_2959 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCE_2960 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCE_2969 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCE_2978 ENOG4107VC0 DNA alkylation repair enzyme BCE_2979 ENOG4107VMI polysaccharide deacetylase BCE_2981 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BCE_2983 ENOG4106ETB IIa component BCE_2986 ENOG4108ZCF integral membrane protein BCE_2987 ENOG4105E0M Sulfatase BCE_2988 ENOG4105C5H ABC transporter BCE_2990 ENOG4105EYF MMPL domain protein BCE_2991 ENOG41082JN Transcriptional regulator BCE_2998 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCE_3005 ENOG41069ER domain protein BCE_3012 ENOG4105D4B ABC, transporter BCE_3013 ENOG4105F5R ABC transporter BCE_3014 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCE_3016 ENOG4105DKT Transcriptional regulator BCE_3019 ENOG41061GT Aldolase BCE_3024 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCE_3031 ENOG4105II7 pyrroline-5-carboxylate reductase BCE_3033 ENOG4107258 Transcriptional regulator BCE_3035 ENOG4105E0Y RtcB Protein BCE_3036 ENOG4105ECK Fatty Acid Desaturase BCE_3038 ENOG4105G6Z alkaline phosphatase BCE_3040 ENOG4105VMP Transcriptional regulator BCE_3042 ENOG41090T1 Membrane BCE_3044 ENOG4108WCX response regulator BCE_3046 ENOG4105KNA -acetyltransferase BCE_3053 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE_3057 ENOG4105C8Y Acetylornithine aminotransferase BCE_3060 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCE_3064 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCE_3073 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE_3075 ENOG4108TVJ Nitroreductase BCE_3076 ENOG4105FS7 Transcriptional regulator BCE_3081 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCE_3083 ENOG4105C19 ABC transporter BCE_3088 ENOG4108DMH HTH_ARAC BCE_3089 ENOG4108XET gCN5-related N-acetyltransferase BCE_3102 ENOG410635A Membrane BCE_3104 ENOG4108IQI permease BCE_3108 ENOG4107ZY0 Phenazine biosynthesis-like protein BCE_3113 ENOG4107RF6 penicillin-binding protein BCE_3121 ENOG4105P4J Allophanate hydrolase, subunit 1 BCE_3122 ENOG4107258 Transcriptional regulator BCE_3124 ENOG4106N3A copper homeostasis protein cutc BCE_3125 ENOG4108ZRV stage ii sporulation protein p BCE_3126 ENOG4105FDT acyl-CoA dehydrogenase BCE_3131 ENOG4105DWD nucleoside recognition domain protein BCE_3137 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCE_3139 ENOG41087PP glycosyltransferase MGT family BCE_3145 ENOG4105E2A Dehydrogenase BCE_3147 ENOG4108FPN Integrase BCE_3148 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE_3154 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCE_3157 ENOG4105CGH 5'-nucleotidase BCE_3160 ENOG4105CHJ isochorismatase hydrolase BCE_3175 ENOG4105FQP Beta-lactamase BCE_3178 ENOG4105EB3 Histidine kinase BCE_3179 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_3183 ENOG4108606 TspO/MBR family BCE_3184 ENOG4105CVP deoxyribo-dipyrimidine photolyase BCE_3188 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BCE_3191 ENOG4108TWJ NADH dehydrogenase subunit 5 BCE_3193 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCE_3194 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_3196 ENOG4107VMI polysaccharide deacetylase BCE_3198 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCE_3199 ENOG4105D7V transposase BCE_3205 ENOG4105Z7P Acetyltransferase (GNAT) family BCE_3208 ENOG4105D6J arsenicaL-resistance protein BCE_3209 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_3210 ENOG41085FC arsR family transcriptional regulator BCE_3214 ENOG4105NAE bifunctional deaminase-reductase domain protein BCE_3219 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCE_3227 ENOG4107P5I polyketide synthase BCE_3228 ENOG4108IG5 Transcriptional regulator BCE_3239 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCE_3240 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_3250 ENOG4106A3M Cytochrome p-450 BCE_3251 ENOG4106A3M Cytochrome p-450 BCE_3252 ENOG4106A3M Cytochrome p-450 BCE_3261 ENOG4105K6H D-cysteine desulfhydrase BCE_3264 ENOG4105JQZ Methyltransferase BCE_3268 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCE_3271 ENOG4105BZU Histidine kinase BCE_3274 ENOG4108U05 Transcriptional regulator BCE_3275 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BCE_3277 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCE_3281 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCE_3284 ENOG4108JQ1 Dehydrogenase BCE_3295 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE_3305 ENOG4108ISG Major Facilitator BCE_3308 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCE_3309 ENOG4105CZM Major Facilitator BCE_3311 ENOG4105RXJ BCE_3312 ENOG4105KPY Small multidrug resistance protein BCE_3313 ENOG4105KBX Transcriptional regulator, TetR family BCE_3315 ENOG4105CRW Short chain fatty acid transporter BCE_3317 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCE_3324 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCE_3345 ENOG4105EKQ RNA-directed DNA polymerase BCE_3347 ENOG4108Z66 YbaK ebsC protein BCE_3352 ENOG4105CA9 Pyruvate kinase BCE_3355 ENOG4108PSK reductase BCE_3357 ENOG4105CJ1 ABC, transporter BCE_3372 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_3373 ENOG4105DKQ ROK family BCE_3375 ENOG4108UW5 maltose o-acetyltransferase BCE_3376 ENOG4105C31 Tryptophanyl-tRNA synthetase BCE_3384 ENOG4108R96 Methyltransferase, YaeB family BCE_3385 ENOG4105DMQ Methyltransferase BCE_3387 ENOG4105EV4 Multidrug resistance protein mdtH BCE_3392 ENOG4105C37 (CBS) domain BCE_3395 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCE_3396 ENOG4105FAW cDP-glucose 4,6-dehydratase BCE_3405 ENOG4105XDF Protein of unknown function (DUF1272) BCE_3406 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCE_3407 ENOG4105CMG Carbohydrate kinase BCE_3408 ENOG4105C6Z Gluconate BCE_3409 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCE_3412 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCE_3416 ENOG4105C44 Serine transporter BCE_3424 ENOG4108TZY GntR Family Transcriptional Regulator BCE_3425 ENOG4105D9R oxidoreductase BCE_3431 ENOG4105JAB phenazine biosynthesis protein, phzf family BCE_3435 ENOG4105KNA -acetyltransferase BCE_3437 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCE_3438 ENOG4105KVH Transcriptional regulator BCE_3450 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCE_3454 ENOG410751J BCE_3459 ENOG4105H3G oxidoreductase BCE_3469 ENOG4105K7K Transcriptional regulator BCE_3470 ENOG4105CIS alcohol dehydrogenase BCE_3476 ENOG4105D7V transposase BCE_3479 ENOG4108TN2 lmbE family BCE_3482 ENOG4107R3E Citrate transporter BCE_3485 ENOG4108MES Periplasmic binding protein BCE_3486 ENOG4105EHG Permease protein BCE_3487 ENOG4105DQ5 transport system permease protein BCE_3488 ENOG4105NX3 Membrane BCE_3493 ENOG4107CUJ Protein of unknown function (DUF2690) BCE_3495 ENOG4107V2S Transcriptional regulator BCE_3499 ENOG4105C98 muts2 protein BCE_3501 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCE_3502 ENOG4105DPN Oligoendopeptidase f BCE_3507 ENOG4108A04 Beta-lactamase BCE_3514 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCE_3516 ENOG4105EEM helicase BCE_3520 ENOG41082BM Transcriptional regulator, arsr family BCE_3521 ENOG4105CIS alcohol dehydrogenase BCE_3523 ENOG4107JM4 Tetratricopeptide repeat BCE_3527 ENOG4105RHY Pfam:UPF0157 BCE_3529 ENOG4105C09 Bile acid BCE_3530 ENOG4105CQB FAD linked oxidase domain protein BCE_3533 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BCE_3541 ENOG4105KT7 mgtC SapB transporter BCE_3544 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_3545 ENOG4105EAB amino acid AbC transporter BCE_3547 ENOG4108HW4 amino acid AbC transporter BCE_3548 ENOG41073R8 VanW family BCE_3550 ENOG4108R1P BCE_3553 ENOG4105VEQ Cold shock protein BCE_3557 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCE_3561 ENOG410904N short-chain dehydrogenase reductase BCE_3564 ENOG4106IQC argininosuccinate lyase BCE_3567 ENOG4108IA2 Sodium pantothenate symporter BCE_3569 ENOG4105C26 Dehydrogenase BCE_3570 ENOG4105CHR reductase BCE_3572 ENOG4105EWU Squalene--hopene cyclase BCE_3574 ENOG4105FR1 rard protein BCE_3575 ENOG410696E Membrane BCE_3578 ENOG4105D1F ATP-binding protein BCE_3580 ENOG4108ZAF Molybdopterin BCE_3581 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCE_3582 ENOG4105D06 uba thif-type nad fad binding protein BCE_3583 ENOG4105TMB Formate nitrite transporter BCE_3585 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCE_3586 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCE_3588 ENOG4108JB9 formate dehydrogenase BCE_3589 ENOG4105E1K spore germination protein BCE_3590 ENOG4105E1K spore germination protein BCE_3604 ENOG4107QJT sodium dicarboxylate symporter BCE_3605 ENOG4108KGH TRANSCRIPTIONal BCE_3607 ENOG4105EMN RNA polymerase sigma factor BCE_3610 ENOG4105CIG ABC transporter BCE_3615 ENOG4105D9R oxidoreductase BCE_3617 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCE_3618 ENOG4105K4P CoA-binding domain protein BCE_3619 ENOG4105C0H protease BCE_3620 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_3621 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BCE_3622 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCE_3625 ENOG4105W8X HesB YadR YfhF-family protein BCE_3631 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCE_3632 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCE_3634 ENOG4108JJA ABC, transporter BCE_3635 ENOG4108I0Z Aconitate hydratase BCE_3641 ENOG4105E5W Transporter BCE_3643 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCE_3647 ENOG4107F3J Amp-dependent synthetase and ligase BCE_3648 ENOG4107ZYJ bioY protein BCE_3649 ENOG4105CEY Amp-dependent synthetase and ligase BCE_3652 ENOG4108IMY Transcriptional regulator BCE_3656 ENOG4105D9G High-affinity BCE_3657 ENOG4105IW1 AmiS UreI transporter BCE_3660 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) BCE_3668 ENOG4107AYK membrAne BCE_3670 ENOG4105BZU Histidine kinase BCE_3671 ENOG4105FBA Phospholipase Carboxylesterase BCE_3672 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCE_3673 ENOG4105CK7 Sodium proline symporter BCE_3674 ENOG4105CBC glutamate synthase BCE_3675 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCE_3676 ENOG4108VJ1 Transcriptional regulator (CarD family BCE_3677 ENOG4108903 Formimidoylglutamase BCE_3682 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BCE_3691 ENOG4105EKQ RNA-directed DNA polymerase BCE_3695 ENOG4107QIV Cytochrome c biogenesis protein BCE_3698 ENOG4105CH2 amidohydrolase BCE_3700 ENOG4105CJ1 ABC, transporter BCE_3702 ENOG4107RSM transcriptional regulator BCE_3704 ENOG41067MG lrgb family BCE_3710 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE_3714 ENOG4105BZ1 (ABC) transporter BCE_3715 ENOG4105BZ1 (ABC) transporter BCE_3723 ENOG4108HW3 (ABC) transporter BCE_3724 ENOG4105CGH 5'-nucleotidase BCE_3726 ENOG4108SVB resolvase BCE_3730 ENOG4105K7K Transcriptional regulator BCE_3731 ENOG4105C5F glutamine synthetase BCE_3732 ENOG4105KV4 Transcriptional regulator BCE_3733 ENOG4105CXI aluminum resistance protein BCE_3734 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCE_3735 ENOG4105EN6 Membrane BCE_3737 ENOG4106F1P AAA ATPase, central domain protein BCE_3743 ENOG41069ER domain protein BCE_3744 ENOG4105DM4 PTS System BCE_3745 ENOG4105DE4 1-phosphofructokinase BCE_3746 ENOG4105E98 transcriptional regulator DeoR family BCE_3747 ENOG4107QW4 alcohol dehydrogenase BCE_3748 ENOG4108SJC Membrane BCE_3751 ENOG4105C85 amino acid BCE_3755 ENOG4105TMB Formate nitrite transporter BCE_3756 ENOG4105K70 DNA-binding protein BCE_3758 ENOG4105C59 p-type ATPase BCE_3759 ENOG410681U heavy metal transport detoxification protein BCE_3761 ENOG4105VPX protein, conserved in bacteria BCE_3763 ENOG4105PGM cation diffusion facilitator family transporter BCE_3767 ENOG4105NIV Esterase BCE_3768 ENOG4105E0A ABC, transporter BCE_3773 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCE_3774 ENOG4105D03 DNA-3-methyladenine glycosylase II BCE_3780 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_3781 ENOG4105BZU Histidine kinase BCE_3788 ENOG41067MG lrgb family BCE_3795 ENOG4105F0V Cell wall hydrolase BCE_3797 ENOG4105E0M Sulfatase BCE_3798 ENOG410890F Dynamin family BCE_3801 ENOG4107QHE Choloylglycine hydrolase BCE_3808 ENOG4105DQU oxidoreductase, subunit beta BCE_3809 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCE_3810 ENOG4108IGT Dipeptidase BCE_3811 ENOG4105MCT stage V sporulation protein S BCE_3812 ENOG4105D48 metallophosphoesterase BCE_3816 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCE_3819 ENOG4105XZV Protein of unknown function (DUF3243) BCE_3820 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCE_3824 ENOG4105UIB (ABC) transporter BCE_3825 ENOG4108JQ9 ABC transporter BCE_3826 ENOG4105DIH basic membrane BCE_3827 ENOG4105FDP GntR family transcriptional regulator BCE_3828 ENOG4107QZI cell division protein FtsK BCE_3831 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCE_3835 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCE_3836 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCE_3838 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCE_3839 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCE_3840 ENOG4105E35 Dipicolinate synthase subunit A BCE_3843 ENOG4105C1V Peptidase, M16 BCE_3847 ENOG4105DTN riboflavin biosynthesis protein ribF BCE_3850 ENOG4105W7A Protein of unknown function (DUF503) BCE_3852 ENOG4105VHM ribosomal protein BCE_3853 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCE_3854 ENOG4105CHV Transcription elongation factor NusA BCE_3856 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCE_3857 ENOG4105EKQ RNA-directed DNA polymerase BCE_3859 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCE_3861 ENOG4105DZP Membrane-associated zinc metalloprotease BCE_3863 ENOG4105KNE Phosphatidate cytidylyltransferase BCE_3873 ENOG4108HE4 integrase family BCE_3875 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCE_3876 ENOG4105C79 DNA protecting protein DprA BCE_3877 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCE_3880 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCE_3885 ENOG4105VB6 UPF0109 protein BCE_3889 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCE_3890 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCE_3893 ENOG4105CHR reductase BCE_3894 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCE_3897 ENOG4105CB5 ATP-dependent DNA helicase recG BCE_3898 ENOG4105DP4 dak2 domain fusion protein ylov BCE_3899 ENOG4108ZAA Alkaline-shock protein BCE_3901 ENOG4105FJ0 thiamine BCE_3902 ENOG4105DJV ribulose-phosphate 3-epimerase BCE_3904 ENOG4105D9P serine threonine protein kinase BCE_3905 ENOG4108ZF3 Phosphatase BCE_3907 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCE_3910 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCE_3911 ENOG4105C25 Primosomal protein n' BCE_3912 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCE_3916 ENOG4105DSJ YicC domain protein BCE_3918 ENOG4105D7V transposase BCE_3919 ENOG4105F23 Fibronectin-binding protein BCE_3921 ENOG4105DC7 peptidase M24 BCE_3937 ENOG4105C34 Pseudouridine synthase BCE_3942 ENOG4105DBK s4 domain protein BCE_3943 ENOG41067XK integral membrane protein BCE_3945 ENOG4105DFA alanine racemase domain protein BCE_3946 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCE_3947 ENOG4105WR5 sporulation protein, YlmC YmxH family BCE_3949 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_3951 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCE_3952 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCE_3954 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BCE_3957 ENOG4105CNI cell division protein FtsW BCE_3960 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCE_3961 ENOG4105CJN penicillin-binding protein BCE_3962 ENOG4105CJN penicillin-binding protein BCE_3963 ENOG41068DC Essential cell division protein (By similarity) BCE_3970 ENOG4105KNH Nucleic acid-binding protein BCE_3972 ENOG41063PX domain protein BCE_3973 ENOG4105D78 K07001 NTE family protein BCE_3975 ENOG4105H20 Sporulation integral membrane protein YlbJ BCE_3977 ENOG4106H78 methyltransferase BCE_3981 ENOG4107TB6 phosphoglycerate mutase BCE_3984 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCE_3990 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCE_3994 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCE_3995 ENOG4105CNI cell division protein FtsW BCE_3998 ENOG4108IAB Phoh family BCE_4002 ENOG4105QA2 BCE_4003 ENOG4105CI3 gtp-binding protein typa BCE_4005 ENOG4105ECY inositol monophosphatase BCE_4009 ENOG4105CXN decarboxylase BCE_4020 ENOG4105CPP Dehydrogenase, E1 component BCE_4023 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCE_4024 ENOG4108X4Q Hydrolase BCE_4026 ENOG4105CN5 Metallo-Beta-Lactamase BCE_4027 ENOG4107ZYR domain protein BCE_4034 ENOG4108XRC Protein of unknown function (DUF458) BCE_4036 ENOG4107IN1 Protein of unknown function (DUF1797) BCE_4039 ENOG4105EPM Diguanylate phosphodiesterase BCE_4040 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCE_4043 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCE_4045 ENOG4105UIN BCE_4058 ENOG4108HGU Histidine kinase BCE_4060 ENOG4105CHM Aminotransferase BCE_4061 ENOG4105FKQ transcriptional regulator BCE_4062 ENOG4105EG2 ABC transporter, permease BCE_4064 ENOG4107FKK extracellular solute-binding protein family 1 BCE_4066 ENOG4105CG3 alpha amylase, catalytic region BCE_4075 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BCE_4076 ENOG4105CHU acetyl-coa acetyltransferase BCE_4083 ENOG4105K7K Transcriptional regulator BCE_4084 ENOG4105DTD Dehydrogenase BCE_4088 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE_4091 ENOG4108NGU Transcriptional regulator BCE_4092 ENOG4108UMN azlc family BCE_4095 ENOG4105CUB amino acid BCE_4101 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCE_4109 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCE_4111 ENOG4106TD9 Diguanylate cyclase BCE_4115 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCE_4118 ENOG4105CID antiterminator BCE_4120 ENOG4105FDP GntR family transcriptional regulator BCE_4122 ENOG4105CE4 GlcNAc 6-P deacetylase BCE_4131 ENOG4107ZE5 PPIases accelerate the folding of proteins BCE_4132 ENOG4105PTM secreted protein BCE_4133 ENOG4105J7I hydrolase BCE_4136 ENOG4105CZ3 stage V sporulation protein ad BCE_4137 ENOG41090VF Stage v sporulation protein ac BCE_4141 ENOG4105C8J )-transporter BCE_4142 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_4144 ENOG41082AN stage II sporulation protein BCE_4145 ENOG4105DZ1 carboxypeptidase BCE_4146 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCE_4147 ENOG4105DVE abc transporter atp-binding protein BCE_4153 ENOG4105D7N magnesium and cobalt transport protein CorA BCE_4158 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE_4160 ENOG4105I3K Ferric uptake regulator, Fur family BCE_4161 ENOG4105MZ9 stage II sporulation protein m BCE_4165 ENOG4105CPC Aldo Keto reductase BCE_4167 ENOG4105RHY Pfam:UPF0157 BCE_4171 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCE_4173 ENOG4105ETE Transcriptional regulator (LacI family BCE_4174 ENOG4108YM7 Gcn5-related n-acetyltransferase BCE_4179 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCE_4180 ENOG4108R6K riboflavin synthase, subunit alpha BCE_4185 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE_4186 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE_4189 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE_4193 ENOG4105DFD Na H antiporter BCE_4194 ENOG4105CGH 5'-nucleotidase BCE_4205 ENOG4108IXY short-chain dehydrogenase reductase BCE_4206 ENOG41069FQ Metallo-beta-lactamase superfamily BCE_4207 ENOG4105II7 pyrroline-5-carboxylate reductase BCE_4208 ENOG4105EJQ L-serine dehydratase BCE_4212 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BCE_4214 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCE_4216 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCE_4217 ENOG4105D9U N-acetyltransferase BCE_4221 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCE_4222 ENOG4108QEG Membrane BCE_4223 ENOG4105CDA abc transporter atp-binding protein BCE_4224 ENOG4105E5Q amino acid AbC transporter BCE_4225 ENOG4108HW3 (ABC) transporter BCE_4228 ENOG4105G7B Protein of unknown function (DUF2992) BCE_4229 ENOG4105E09 nadh pyrophosphatase BCE_4230 ENOG4108QY0 Membrane BCE_4232 ENOG4105C7S Dehydrogenase BCE_4233 ENOG4105CPP Dehydrogenase, E1 component BCE_4237 ENOG4107RDP Dehydrogenase BCE_4239 ENOG4108JUB Transcriptional regulator BCE_4240 ENOG4106CCJ Protein of unknown function (DUF2627) BCE_4241 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCE_4243 ENOG4107QQR Sporulation BCE_4245 ENOG4105S1Z Stage IV sporulation protein B BCE_4246 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCE_4248 ENOG4105DX0 Hemolysin A BCE_4251 ENOG4105CTB Polyprenyl synthetase BCE_4256 ENOG4108ZSR alkaline shock protein BCE_4257 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCE_4261 ENOG410644B Stage III sporulation protein af BCE_4263 ENOG4105KQ4 Stage iii sporulation protein ad BCE_4264 ENOG4108CQH stage III sporulation protein AC BCE_4265 ENOG4105KR5 Stage iii sporulation protein BCE_4266 ENOG4105CD2 stage iii sporulation protein aa BCE_4271 ENOG4105DC7 peptidase M24 BCE_4274 ENOG4105CBJ Metal-dependent enzyme BCE_4276 ENOG4107YBY Hydrolase BCE_4284 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BCE_4285 ENOG4105WZW rhodanese family BCE_4289 ENOG41080TC multidrug resistance protein BCE_4298 ENOG4105CJ1 ABC, transporter BCE_4299 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCE_4306 ENOG4105C0D helicase BCE_4332 ENOG4105C3R Methionine synthase BCE_4336 ENOG4105C28 cystathionine BCE_4337 ENOG4105C28 cystathionine BCE_4341 ENOG4105C5X domain protein BCE_4343 ENOG4105DKQ ROK family BCE_4345 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCE_4348 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCE_4349 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCE_4350 ENOG4105E2Z phosphate ABC transporter (Permease BCE_4351 ENOG4105C8U phosphate abc transporter BCE_4352 ENOG4105PWN phosphate abc transporter BCE_4353 ENOG4107RF6 penicillin-binding protein BCE_4355 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE_4359 ENOG4105N80 Ferric uptake regulator, Fur family BCE_4361 ENOG4105FDK ABC transporter BCE_4362 ENOG4108JYZ YitT family BCE_4363 ENOG41069ZM Protein of unknown function (DUF2624) BCE_4369 ENOG4105EGD dinuclear metal center protein, YbgI family BCE_4372 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_4374 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCE_4380 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCE_4381 ENOG4105KG3 cytidine deaminase BCE_4382 ENOG4107YR5 Diacylglycerol kinase BCE_4384 ENOG4105CTJ Metal Dependent Phosphohydrolase BCE_4385 ENOG4105C9A Phoh family BCE_4388 ENOG41068P3 sporulation protein YqfC BCE_4389 ENOG4105KTH gatB Yqey BCE_4391 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCE_4392 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCE_4398 ENOG4105CSA Coproporphyrinogen iii oxidase BCE_4399 ENOG4105KVH Transcriptional regulator BCE_4404 ENOG4105TQK DNA polymerase iii, delta' subunit BCE_4406 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCE_4407 ENOG4108UK2 deaminase BCE_4408 ENOG4105KQC Competence protein BCE_4410 ENOG4105DXX methyltransferase BCE_4412 ENOG4108WF2 Metal Dependent Phosphohydrolase BCE_4414 ENOG410812S Rna-binding protein BCE_4416 ENOG4105CQW ribosome biogenesis GTPase YqeH BCE_4417 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCE_4421 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_4427 ENOG4105G6Z alkaline phosphatase BCE_4430 ENOG4108MUZ hydrolase BCE_4437 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCE_4439 ENOG4105MIR Phenylalanine 4-monooxygenase BCE_4441 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_4449 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCE_4450 ENOG4108HUF Transporter BCE_4453 ENOG4108EKI Dehydrogenase BCE_4454 ENOG4105C28 cystathionine BCE_4460 ENOG4107XRG penicillin-binding protein BCE_4463 ENOG4105CFP Peptidase U32 BCE_4464 ENOG4105XYU peptidase (U32 family) BCE_4465 ENOG4108VQJ O-methyltransferase BCE_4466 ENOG4105HHA aminodeoxychorismate lyase BCE_4473 ENOG4105C02 permease BCE_4476 ENOG41060CR BCE_4477 ENOG4105C7H Helicase, RecD TraA family BCE_4480 ENOG4105C3J Cysteine desulfurase BCE_4482 ENOG4105D1H recombination factor protein RarA BCE_4483 ENOG4108VCI transcription factor, rsfa family BCE_4484 ENOG4105CUZ uba thif-type nad fad binding protein BCE_4491 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCE_4493 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCE_4494 ENOG41076HS cation diffusion facilitator family transporter BCE_4496 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCE_4498 ENOG4105CKP Polysaccharide Biosynthesis Protein BCE_4499 ENOG4108QG2 Membrane BCE_4501 ENOG4105VIE preprotein translocase, subunit YajC BCE_4504 ENOG41061AI Protein of unknown function (DUF2905) BCE_4508 ENOG4108IPJ Membrane BCE_4509 ENOG41082BM Transcriptional regulator, arsr family BCE_4514 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCE_4515 ENOG4108IYU L-aspartate oxidase BCE_4518 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCE_4519 ENOG41082BM Transcriptional regulator, arsr family BCE_4521 ENOG4105C26 Dehydrogenase BCE_4524 ENOG4108RPX mosc domain containing protein BCE_4525 ENOG4105CQC Prephenate dehydratase BCE_4530 ENOG4105EWM Histidine kinase BCE_4535 ENOG4105X36 (ribosomal) protein BCE_4537 ENOG4105C03 ribonuclease BCE_4540 ENOG4107QMS site-determining protein BCE_4543 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCE_4544 ENOG4105DFF Rod shape-determining protein mreb BCE_4548 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCE_4551 ENOG41068KH stage VI sporulation protein D BCE_4553 ENOG4105D52 delta-aminolevulinic acid dehydratase BCE_4558 ENOG4105K56 Transcriptional regulator BCE_4562 ENOG4108IUQ atp-dependent protease BCE_4570 ENOG4108QCI YvbH-like oligomerisation region BCE_4577 ENOG41069I7 BCE_4584 ENOG4105M59 Phosphodiesterase, mj0936 family BCE_4587 ENOG4108XJQ germination protein BCE_4590 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_4592 ENOG4105KBX Transcriptional regulator, TetR family BCE_4594 ENOG4105PFC Transcriptional regulator BCE_4596 ENOG4107WZZ SMC domain protein BCE_4610 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCE_4626 ENOG4105PFC Transcriptional regulator BCE_4628 ENOG4105DZC cytosine deaminase BCE_4629 ENOG4105DZC cytosine deaminase BCE_4630 ENOG41067S9 phage shock protein C, PspC BCE_4631 ENOG4108JCI Transcriptional regulator BCE_4633 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCE_4634 ENOG4108Z40 Transcriptional regulator BCE_4635 ENOG4105RHA ABC transporter, permease BCE_4636 ENOG4108IUX (ABC) transporter BCE_4638 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCE_4639 ENOG4105ER2 Ompa motb domain protein BCE_4640 ENOG4105E14 MotA TolQ exbB proton channel BCE_4641 ENOG4108VXD carboxy-peptidase BCE_4643 ENOG4105E33 succinate dehydrogenase BCE_4645 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCE_4648 ENOG4105K63 Thioredoxin BCE_4649 ENOG4105C10 Electron transfer flavoprotein BCE_4650 ENOG4105BZJ Electron transfer flavoprotein BCE_4651 ENOG41060WC Enoyl-CoA hydratase BCE_4652 ENOG4107Z3H Transcriptional regulator, TetR family BCE_4653 ENOG4105CEY Amp-dependent synthetase and ligase BCE_4662 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE_4665 ENOG4105DR4 Methyltransferase BCE_4667 ENOG4105KFN sortase, SrtB family BCE_4668 ENOG4105E0A ABC, transporter BCE_4671 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCE_4672 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCE_4674 ENOG4105FE9 pseudouridine synthase BCE_4679 ENOG4105DCG PHP domain protein BCE_4688 ENOG4108RWN rrna methyltransferase BCE_4699 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE_4700 ENOG4105CW7 secretion protein, HlyD family BCE_4701 ENOG4108JGH Tetr family transcriptional regulator BCE_4702 ENOG4105CN9 Peptidase m42 family protein BCE_4706 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCE_4707 ENOG4105C22 threonyL-tRNA synthetase BCE_4708 ENOG4108TDW sporulation protein YtxC BCE_4712 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCE_4714 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCE_4718 ENOG4105C2M dna polymerase I BCE_4719 ENOG4105BZU Histidine kinase BCE_4720 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE_4724 ENOG4108HMX isocitrate dehydrogenase (NADP) BCE_4725 ENOG4105BZN citrate synthase BCE_4727 ENOG4108REF Sporulation integral membrane protein ytvi BCE_4728 ENOG4105FS0 cytoplasmic membrane protein BCE_4733 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCE_4734 ENOG4105C6K Malic enzyme BCE_4735 ENOG4105C0B DNA polymerase III (alpha subunit) BCE_4736 ENOG4105VV2 BCE_4738 ENOG4105SFS phosphoesterase RecJ domain protein BCE_4748 ENOG4105DC7 peptidase M24 BCE_4755 ENOG41082W1 Cupin 2, conserved barrel domain protein BCE_4760 ENOG4107YZX Universal stress protein BCE_4769 ENOG4108JYZ YitT family BCE_4775 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCE_4776 ENOG4105KBJ sporulation protein ytfj BCE_4779 ENOG4105EFZ amidohydrolase BCE_4781 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCE_4787 ENOG4105C5Q Transcriptional regulator BCE_4789 ENOG4105U5Y Transcriptional regulator BCE_4791 ENOG4105C28 cystathionine BCE_4798 ENOG4105EMN RNA polymerase sigma factor BCE_4802 ENOG4105F1V Acetoin utilization protein BCE_4803 ENOG4105W87 Cbs domain BCE_4804 ENOG4105DGU Histone deacetylase BCE_4807 ENOG4105EP9 oxidoreductase BCE_4813 ENOG4105ETE Transcriptional regulator (LacI family BCE_4820 ENOG4105C88 aminopeptidase BCE_4826 ENOG4108IPJ Membrane BCE_4828 ENOG4105K7K Transcriptional regulator BCE_4834 ENOG4108VDD TRNA binding domain protein BCE_4840 ENOG4105C8F Beta-lactamase domain protein BCE_4843 ENOG4108V15 phosphotransferase enzyme family BCE_4844 ENOG4108IUM Glycogen debranching enzyme BCE_4846 ENOG4107QSE Dipeptidase BCE_4847 ENOG4105YW5 deoR family transcriptional regulator BCE_4850 ENOG4105CBX hi0933 family BCE_4857 ENOG4108VJ1 Transcriptional regulator (CarD family BCE_4858 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCE_4862 ENOG4108ZAF Molybdopterin BCE_4863 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCE_4864 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCE_4866 ENOG4105D06 uba thif-type nad fad binding protein BCE_4867 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCE_4871 ENOG41085GJ domain protein BCE_4873 ENOG4105DWV Homoserine O-trans-acetylase BCE_4875 ENOG4108B31 Spore germination protein BCE_4883 ENOG410605W Major Facilitator BCE_4884 ENOG4107S91 Sodium hydrogen exchanger BCE_4885 ENOG4105NCW Trka-c domain protein BCE_4888 ENOG4105C19 ABC transporter BCE_4892 ENOG4105N5T Radical SAM Protein BCE_4894 ENOG4105CJ1 ABC, transporter BCE_4900 ENOG4105D78 K07001 NTE family protein BCE_4904 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCE_4905 ENOG4108Z0R Transferase BCE_4906 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCE_4907 ENOG4105BZF Glycosyl transferase (Group 1 BCE_4909 ENOG4108RIR Molybdenum cofactor biosynthesis protein BCE_4913 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE_4922 ENOG4105EGD dinuclear metal center protein, YbgI family BCE_4926 ENOG4105BZU Histidine kinase BCE_4927 ENOG4105BZU Histidine kinase BCE_4929 ENOG4107S9D Alpha beta hydrolase BCE_4930 ENOG4107T7U Sulfatase BCE_4935 ENOG4105D2X ABC transporter substrate-binding protein BCE_4937 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCE_4948 ENOG4108V2W Carbonate dehydratase BCE_4949 ENOG4105C4M (Ubiquinol oxidase) subunit I BCE_4950 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCE_4961 ENOG41087YS Phage shock protein A BCE_4968 ENOG4105BZU Histidine kinase BCE_4969 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_4975 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCE_4976 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCE_4982 ENOG4107ZTW SNARE associated Golgi BCE_4985 ENOG4105C19 ABC transporter BCE_4986 ENOG41086D8 Transcriptional regulator BCE_4988 ENOG41082BM Transcriptional regulator, arsr family BCE_4998 ENOG4105C6Z Gluconate BCE_4999 ENOG4105FDP GntR family transcriptional regulator BCE_5003 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCE_5011 ENOG4105DTQ mandelate racemase muconate lactonizing BCE_5013 ENOG4108IPT Naphthoate synthase BCE_5014 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCE_5016 ENOG4105E4F Isochorismate synthase BCE_5017 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCE_5019 ENOG4105VEQ Cold shock protein BCE_5031 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCE_5034 ENOG4105KT7 mgtC SapB transporter BCE_5035 ENOG4107PBV potassium channel BCE_5038 ENOG4105WG9 Conserved Protein BCE_5040 ENOG4105CHM Aminotransferase BCE_5041 ENOG4108ZB6 transcriptional regulator AsnC family BCE_5042 ENOG4105C5I Dehydrogenase BCE_5043 ENOG4108MUZ hydrolase BCE_5045 ENOG4105C87 Aminotransferase class I and II BCE_5048 ENOG4105Y38 Kinase-associated protein B BCE_5050 ENOG4107R3E Citrate transporter BCE_5053 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCE_5054 ENOG4105KA0 thioesterase Superfamily protein BCE_5057 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCE_5061 ENOG41069ER domain protein BCE_5064 ENOG4105CEP NADH dehydrogenase BCE_5069 ENOG4105EWC Purine nucleoside phosphorylase BCE_5071 ENOG4108VQJ O-methyltransferase BCE_5073 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCE_5078 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCE_5079 ENOG4105C4B ABC transporter, permease BCE_5080 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCE_5086 ENOG41083MR nifu domain-containing protein BCE_5089 ENOG4108W5N phosphatidylglycerophosphatase a BCE_5093 ENOG4105DAX Pfam:DUF2983 BCE_5095 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCE_5096 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCE_5099 ENOG4105CBT Fructose-1,6-bisphosphatase BCE_5102 ENOG4105MMD transcriptional regulator BCE_5103 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCE_5104 ENOG4107TXC Transcriptional regulator BCE_5105 ENOG41090T1 Membrane BCE_5110 ENOG4105FAA peptidase M23 BCE_5112 ENOG4105KZD Domain of unknown function (DUF1805) BCE_5113 ENOG4107R8B 5'-nucleotidase BCE_5116 ENOG4105DIW FeS assembly protein SUFB BCE_5117 ENOG4108UNV SUF system FeS assembly protein, NifU family BCE_5118 ENOG4105C9B Cysteine desulfurase BCE_5119 ENOG4105JRK feS assembly protein SufD BCE_5120 ENOG4105C3K feS assembly ATPase SufC BCE_5122 ENOG4105D01 (LipO)protein BCE_5123 ENOG4105D01 (LipO)protein BCE_5124 ENOG4108UMI ABC transporter, permease BCE_5131 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCE_5141 ENOG4108W8B Beta-lactamase domain protein BCE_5142 ENOG4105C1G acyl-Coa dehydrogenase BCE_5143 ENOG4105CHU acetyl-coa acetyltransferase BCE_5147 ENOG4105DZ1 carboxypeptidase BCE_5151 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE_5156 ENOG4108SUT Major Facilitator Superfamily BCE_5157 ENOG4107R7I amino acid BCE_5161 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCE_5163 ENOG4107AYK membrAne BCE_5170 ENOG4107ZTW SNARE associated Golgi BCE_5172 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCE_5173 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_5174 ENOG4105BZU Histidine kinase BCE_5180 ENOG4105C8Q Methyl-accepting chemotaxis BCE_5181 ENOG4105C8Q Methyl-accepting chemotaxis BCE_5182 ENOG4105VG1 fes assembly suf system protein BCE_5183 ENOG4105D4Y metalloprotease BCE_5187 ENOG4107S91 Sodium hydrogen exchanger BCE_5188 ENOG4105NCW Trka-c domain protein BCE_5191 ENOG4108RMU ferritin dps family protein BCE_5194 ENOG4108URH decarboxylase BCE_5198 ENOG4105D9N nucleoside BCE_5199 ENOG4105D9N nucleoside BCE_5202 ENOG4108RYK Nad-dependent epimerase dehydratase BCE_5206 ENOG4105CV8 reductase BCE_5207 ENOG4105F27 Major Facilitator BCE_5208 ENOG4105KVH Transcriptional regulator BCE_5214 ENOG4105C8Q Methyl-accepting chemotaxis BCE_5220 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE_5223 ENOG4108IPW abc transporter atp-binding protein BCE_5224 ENOG4105CM4 permease protein BCE_5232 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCE_5234 ENOG4105XZU Preprotein translocase, subunit SecG BCE_5235 ENOG41067MG lrgb family BCE_5245 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_5249 ENOG41090VF Stage v sporulation protein ac BCE_5250 ENOG4105CZ3 stage V sporulation protein ad BCE_5253 ENOG4108QY0 Membrane BCE_5256 ENOG4105KRI phosphocarrier protein (HPr BCE_5258 ENOG4105CHW UPF0052 protein BCE_5260 ENOG4108Z4K mutator MutT protein BCE_5262 ENOG4105C3M thioredoxin reductase BCE_5264 ENOG4108S4C acetyltransferase BCE_5268 ENOG41086DT Membrane protein of unknown function BCE_5271 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCE_5275 ENOG4107TXC Transcriptional regulator BCE_5280 ENOG4105DUM transcriptional regulator, lysR family BCE_5282 ENOG4108WS4 fmn reductase BCE_5283 ENOG4105C5H ABC transporter BCE_5285 ENOG4105BZ1 (ABC) transporter BCE_5288 ENOG4105CN1 protease BCE_5289 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCE_5290 ENOG4105CAK Cell division ATP-binding protein ftsE BCE_5296 ENOG4105MS2 ribosomal subunit Interface protein BCE_5298 ENOG4105VEQ Cold shock protein BCE_5299 ENOG41081UC Inherit from COG: Competence protein BCE_5301 ENOG4105K4H Nlp p60 protein BCE_5302 ENOG4105KVH Transcriptional regulator BCE_5305 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCE_5306 ENOG4108KGH TRANSCRIPTIONal BCE_5307 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCE_5308 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCE_5311 ENOG4105ESV Glycosyl transferase, family 4 BCE_5313 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCE_5314 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCE_5318 ENOG4105F8D glycoside hydrolase family 4 BCE_5319 ENOG4105VCP PTS System BCE_5320 ENOG4105CK1 PTS System BCE_5324 ENOG4105VCP PTS System BCE_5326 ENOG4105VZJ PTS System BCE_5329 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BCE_5334 ENOG4105ECB domain protein BCE_5335 ENOG4107RSM transcriptional regulator BCE_5342 ENOG4105DAA L-lactate BCE_5345 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCE_5348 ENOG4105E0M Sulfatase BCE_5356 ENOG4107R8N Glycosyl transferase, family 2 BCE_5358 ENOG4105C94 Transporter BCE_5360 ENOG41069ER domain protein BCE_5363 ENOG4105KBK Zinc finger, swim domain protein BCE_5364 ENOG4105C0D helicase BCE_5370 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE_5372 ENOG4107RBB ABC transporter, permease BCE_5373 ENOG4105C19 ABC transporter BCE_5375 ENOG4105CXY transporter BCE_5378 ENOG41065SU Two-component system sensor kinase BCE_5379 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_5380 ENOG4105CMR udp-glucose 4-epimerase BCE_5381 ENOG4105CMR udp-glucose 4-epimerase BCE_5383 ENOG4108KGH TRANSCRIPTIONal BCE_5385 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCE_5390 ENOG4108KMV Glycosyl transferase (Group 1 BCE_5393 ENOG4105D3Q Sugar transferase BCE_5394 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BCE_5396 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCE_5397 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BCE_5398 ENOG4107YJ4 chain length determinant protein BCE_5399 ENOG4105HTX biosynthesis protein BCE_5400 ENOG4108QV3 biosynthesis protein BCE_5405 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCE_5407 ENOG4105FRN stage II sporulation protein BCE_5410 ENOG4105DY9 regulatoR BCE_5414 ENOG4106778 Protein of unknown function (DUF1146) BCE_5415 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCE_5416 ENOG4105C8S subunit m BCE_5417 ENOG4105D65 subunit l BCE_5423 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCE_5426 ENOG4105BZU Histidine kinase BCE_5436 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCE_5437 ENOG41062M3 atp synthase BCE_5443 ENOG4108YZG isomerase BCE_5446 ENOG4108VGI doxx family BCE_5447 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCE_5452 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCE_5454 ENOG4108ZXQ stage ii sporulation protein r BCE_5455 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCE_5456 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCE_5460 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCE_5462 ENOG4105CBT Fructose-1,6-bisphosphatase BCE_5463 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCE_5472 ENOG4105C1G acyl-Coa dehydrogenase BCE_5473 ENOG4105C1G acyl-Coa dehydrogenase BCE_5474 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCE_5476 ENOG4105DF6 Fe-S oxidoreductase BCE_5479 ENOG4105BZU Histidine kinase BCE_5483 ENOG4105BZU Histidine kinase BCE_5484 ENOG4105KCT ABC transporter BCE_5485 ENOG4108M15 ABC transporter BCE_5486 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCE_5488 ENOG4105IIU Aminopeptidase BCE_5492 ENOG4105JVQ RNA Polymerase BCE_5494 ENOG410684U Domain of unknown function (DUF1934) BCE_5498 ENOG4105CYW agmatinase BCE_5501 ENOG4105DXB Major Facilitator superfamily BCE_5502 ENOG4107SWG transcriptional regulator MERR family BCE_5503 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCE_5504 ENOG4105BZ4 penicillin-binding protein BCE_5505 ENOG4108XFG YwhD family BCE_5506 ENOG4108Z4T Peptidase M50 BCE_5507 ENOG41069HH 4-oxalocrotonate tautomerase BCE_5508 ENOG4105DCI Phosphohydrolase BCE_5509 ENOG4108MES Periplasmic binding protein BCE_5510 ENOG4105E0A ABC, transporter BCE_5511 ENOG4105EHG Permease protein BCE_5512 ENOG4105DQ5 transport system permease protein BCE_5514 ENOG4108VCI transcription factor, rsfa family BCE_5516 ENOG4108IJ2 phosphate acetyltransferase BCE_5519 ENOG4108VKI Cell wall hydrolase BCE_5523 ENOG4105NCW Trka-c domain protein BCE_5525 ENOG410667J hydrolase BCE_5526 ENOG4105VCH membrane BCE_5528 ENOG4108TU7 Inherit from COG: (ABC) transporter BCE_5529 ENOG4105CJ1 ABC, transporter BCE_5530 ENOG41090WU lipolytic protein G-D-S-L family BCE_5533 ENOG4105D6E homoserine dehydrogenase BCE_5538 ENOG4108Y4K DNA-binding transcriptional activator BCE_5540 ENOG4105WH1 Two component transcriptional regulator luxr family BCE_5541 ENOG4105BZU Histidine kinase BCE_5542 ENOG4105DWF phosphomethylpyrimidine kinase BCE_5543 ENOG4105BZU Histidine kinase BCE_5544 ENOG4105VCD cytoplasmic protein BCE_5545 ENOG4105D22 carbon starvation protein BCE_5546 ENOG4105DY9 regulatoR BCE_5547 ENOG41079KZ Major Facilitator Superfamily BCE_5549 ENOG4105CG5 Glycosyl transferase (Group 1 BCE_5551 ENOG4105EN6 Membrane BCE_5552 ENOG4106YBV Methyl-accepting chemotaxis BCE_5554 ENOG4108S4H thioesterase Superfamily protein BCE_5557 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BCE_5561 ENOG4107S6X Glycosyl transferase, family 2 BCE_5564 ENOG4105C5H ABC transporter BCE_5565 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE_5567 ENOG41067SE Tetr family transcriptional regulator BCE_5569 ENOG4105E0X reductase BCE_5570 ENOG4106F5Q Membrane BCE_5573 ENOG4105DY9 regulatoR BCE_5574 ENOG4108HRK Histidine kinase BCE_5576 ENOG4107RGD Major Facilitator superfamily BCE_5579 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE_5581 ENOG4105IW1 AmiS UreI transporter BCE_5588 ENOG4105CMR udp-glucose 4-epimerase BCE_5590 ENOG4108UT2 hemolysin iii BCE_5592 ENOG4105C1J atp-dependent rna helicase BCE_5596 ENOG4105DPN Oligoendopeptidase f BCE_5598 ENOG4107Y5K Resolvase BCE_5610 ENOG4105C0H protease BCE_5611 ENOG4105Q2H domain protein BCE_5614 ENOG4105BZU Histidine kinase BCE_5615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_5618 ENOG4105CDU Replicative dna helicase BCE_5619 ENOG4105CDU Replicative dna helicase BCE_5621 ENOG4105BZR domain protein BCE_5622 ENOG4108XMW Membrane BCE_5624 ENOG4108UUM single-stranded DNA-binding protein BCE_5626 ENOG4105C3G gtp-binding protein BCE_5627 ENOG4105VDK protein, conserved in bacteria BCE_5628 ENOG4105D8X mechanosensitive ion channel BCE_5629 ENOG4108ZDA Sporulation protein YyaC BCE_5630 ENOG4105FA0 parb-like partition protein BCE_5631 ENOG4107QJE Chromosome Partitioning Protein BCE_5637 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCE_A0001 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE_A0015 ENOG4105DHF Membrane BCE_A0034 ENOG4105EKQ RNA-directed DNA polymerase BCE_A0056 ENOG4105DQ6 Transposase BCE_A0057 ENOG4105IYK transposase BCE_A0067 ENOG4105D7V transposase BCE_A0073 ENOG4107QZI cell division protein FtsK BCE_A0075 ENOG4105EKQ RNA-directed DNA polymerase BCE_A0089 ENOG4105EKQ RNA-directed DNA polymerase BCE_A0120 ENOG4105EKQ RNA-directed DNA polymerase BCE_A0146 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCE_A0151 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BCE_A0159 ENOG4105D6J arsenicaL-resistance protein BCE_A0160 ENOG41082YX Transcriptional regulator, arsr family BCE_A0165 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCE_A0167 ENOG41067QW Transcriptional regulator BCE_A0168 ENOG4105CJ3 phosphate transporter BCE_A0169 ENOG41085FC arsR family transcriptional regulator BCE_A0172 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCE_A0182 ENOG4105C59 p-type ATPase BCE_A0183 ENOG4105VPX protein, conserved in bacteria BCE_A0184 ENOG4105DSE periplasmic solute binding protein BCE_A0205 ENOG4105K63 Thioredoxin BCE_A0208 ENOG4105EAB amino acid AbC transporter BCE_A0209 ENOG4105E5Q amino acid AbC transporter BCE_A0210 ENOG4105CDA abc transporter atp-binding protein BCE_A0212 ENOG4107R16 Multicopper oxidase BCE_A0213 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE_A0214 ENOG4105BZU Histidine kinase BCE_A0218 ENOG4108ZRV stage ii sporulation protein p BCE_A0226 ENOG4108IBT Inherit from COG: transposase BCE_A0232 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE_A0235 ENOG4105KRN Transcriptional regulator, abrb family BCE_A0241 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCE_A0242 ENOG4108FPN Integrase