locus-tag	class	description
BC_0002	COG0592	DNA-directed DNA polymerase activity
BC_0003	COG2501	S4 domain
BC_0005	COG0187	DNA topoisomerase II activity
BC_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC_0013	COG0517	IMP dehydrogenase activity
BC_0013	COG0516	GMP reductase activity
BC_0014	COG1686	Belongs to the peptidase S11 family
BC_0021	COG1428	Deoxynucleoside kinase
BC_0022	COG1335	isochorismatase
BC_0023	COG0590	tRNA wobble adenosine to inosine editing
BC_0024	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC_0035	COG1982	Orn Lys Arg decarboxylase major
BC_0037	COG0470	DNA polymerase III
BC_0038	COG1774	PSP1 C-terminal conserved region
BC_0040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BC_0041	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BC_0042	COG2002	toxin-antitoxin pair type II binding
BC_0044	COG0084	hydrolase, TatD family'
BC_0048	COG4466	Protein conserved in bacteria
BC_0051	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC_0052	COG0251	oxidation-reduction process
BC_0055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC_0058	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC_0059	COG2002	toxin-antitoxin pair type II binding
BC_0060	COG2244	polysaccharide biosynthetic process
BC_0061	COG3956	TIGRFAM MazG family protein
BC_0062	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BC_0066	COG1098	S1 RNA binding domain
BC_0069	COG2208	phosphoserine phosphatase activity
BC_0072	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC_0075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC_0076	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC_0077	COG0512	Glutamine amidotransferase of anthranilate synthase
BC_0078	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC_0079	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC_0080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC_0081	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC_0082	COG1396	sequence-specific DNA binding
BC_0083	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC_0100	COG3880	PFAM UvrB UvrC protein
BC_0102	COG0542	response to heat
BC_0103	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BC_0105	COG4956	integral membrane protein (PIN domain superfamily)
BC_0109	COG1045	serine acetyltransferase
BC_0112	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC_0113	COG3688	RNA-binding protein containing a PIN domain
BC_0115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC_0116	COG0250	Participates in transcription elongation, termination and antitermination
BC_0121	COG2813	Specifically methylates the guanine in position
BC_0124	COG1358	cellular component organization or biogenesis
BC_0146	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BC_0153	COG0024	Methionine aminopeptidase
BC_0155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC_0162	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BC_0167	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC_0168	COG0489	protein tyrosine kinase activity
BC_0170	COG2194	sulfuric ester hydrolase activity
BC_0171	COG0726	polysaccharide deacetylase
BC_0186	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC_0187	COG4856	YbbR-like protein
BC_0195	COG1028	Short-chain dehydrogenase reductase Sdr
BC_0196	COG2011	ABC-type metal ion transport system permease component
BC_0198	COG1464	Belongs to the NlpA lipoprotein family
BC_0199	COG0604	alcohol dehydrogenase
BC_0201	COG0277	FAD linked oxidase domain protein
BC_0202	COG2271	Major facilitator Superfamily
BC_0204	COG2814	Major facilitator Superfamily
BC_0207	COG0601	transmembrane transport
BC_0208	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC_0209	COG0444	Belongs to the ABC transporter superfamily
BC_0210	COG4608	Belongs to the ABC transporter superfamily
BC_0211	COG4166	transmembrane transport
BC_0213	COG2207	Transcriptional regulator
BC_0215	COG4166	transmembrane transport
BC_0216	COG4166	transmembrane transport
BC_0217	COG0656	L-ascorbic acid biosynthetic process
BC_0220	COG4149	molybdate abc transporter
BC_0221	COG0725	ABC transporter, periplasmic molybdate-binding protein
BC_0222	COG1910	domain protein
BC_0225	COG0697	spore germination
BC_0228	COG0204	Acyl-transferase
BC_0230	COG1609	Transcriptional regulator
BC_0232	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_0235	COG5298	Protein conserved in bacteria
BC_0239	COG0488	(ABC) transporter
BC_0241	COG0747	negative chemotaxis
BC_0242	COG0601	transmembrane transport
BC_0244	COG0444	Belongs to the ABC transporter superfamily
BC_0245	COG4608	Belongs to the ABC transporter superfamily
BC_0246	COG0561	phosphatase activity
BC_0252	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BC_0253	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC_0255	COG0531	amino acid
BC_0256	COG2814	Major facilitator Superfamily
BC_0258	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC_0260	COG4294	response to UV
BC_0261	COG0705	Rhomboid family
BC_0263	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC_0264	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC_0265	COG0864	Transcriptional regulator
BC_0266	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC_0267	COG2183	response to ionizing radiation
BC_0286	COG0802	atpase or kinase
BC_0287	COG1214	PFAM Peptidase M22, glycoprotease
BC_0288	COG0456	acetyltransferase
BC_0290	COG0488	(ABC) transporter
BC_0293	COG1266	CAAX protease self-immunity
BC_0297	COG2252	PERMEase
BC_0299	COG5002	protein histidine kinase activity
BC_0304	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC_0310	COG2226	methyltransferase
BC_0312	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC_0314	COG1215	transferase activity, transferring glycosyl groups
BC_0318	COG0697	spore germination
BC_0323	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC_0324	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC_0325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC_0327	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC_0330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BC_0332	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC_0334	COG0151	Belongs to the GarS family
BC_0340	COG0210	DNA helicase
BC_0342	COG4851	CamS sex pheromone cAM373 precursor
BC_0345	COG1335	isochorismatase
BC_0347	COG2011	ABC-type metal ion transport system permease component
BC_0349	COG4682	membrane
BC_0353	COG1597	lipid kinase activity
BC_0355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC_0357	COG1012	belongs to the aldehyde dehydrogenase family
BC_0358	COG2076	Multidrug Resistance protein
BC_0360	COG2309	aminopeptidase activity
BC_0363	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_0365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC_0368	COG4807	Protein conserved in bacteria
BC_0374	COG1473	amidohydrolase
BC_0377	COG0450	alkyl hydroperoxide reductase
BC_0378	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BC_0380	COG0235	Class ii aldolase
BC_0381	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_0382	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_0383	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_0388	COG0166	Belongs to the GPI family
BC_0393	COG5002	protein histidine kinase activity
BC_0397	COG3541	Predicted nucleotidyltransferase
BC_0398	COG2814	Major facilitator Superfamily
BC_0399	COG0723	plastoquinol--plastocyanin reductase activity
BC_0399	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC_0401	COG0765	amino acid transport
BC_0402	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC_0403	COG1126	abc transporter atp-binding protein
BC_0404	COG0840	transmembrane signaling receptor activity
BC_0409	COG0549	Belongs to the carbamate kinase family
BC_0410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC_0412	COG0277	FAD linked oxidase domain protein
BC_0413	COG0366	Alpha amylase catalytic
BC_0414	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_0414	COG2190	(PTS) system
BC_0414	COG1263	PTS System
BC_0421	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BC_0425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC_0426	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC_0427	COG1116	anion transmembrane transporter activity
BC_0428	COG0488	(ABC) transporter
BC_0436	COG2270	Major facilitator Superfamily
BC_0442	COG2310	stress, protein
BC_0443	COG2310	stress, protein
BC_0444	COG2310	stress, protein
BC_0445	COG0861	Integral membrane protein TerC family
BC_0447	COG3853	Toxic anion resistance protein (TelA)
BC_0450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC_0452	COG1295	ribonuclease BN
BC_0453	COG2217	Heavy metal translocating P-type atpase
BC_0454	COG0697	spore germination
BC_0456	COG0681	Belongs to the peptidase S26 family
BC_0458	COG0586	Pfam SNARE associated Golgi protein
BC_0461	COG3871	stress protein (general stress protein 26)
BC_0462	COG0387	Pfam Sodium calcium exchanger
BC_0464	COG0535	radical SAM domain protein
BC_0468	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BC_0473	COG3829	transcription factor binding
BC_0476	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC_0482	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_0482	COG1263	PTS System
BC_0483	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC_0486	COG0463	Glycosyl transferase, family 2
BC_0488	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC_0488	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC_0492	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BC_0496	COG1228	amidohydrolase
BC_0497	COG1090	epimerase
BC_0503	COG1988	membrane-bound metal-dependent
BC_0504	COG1194	a g-specific adenine glycosylase
BC_0509	COG1132	(ABC) transporter
BC_0510	COG4129	membrane
BC_0511	COG0067	glutamate synthase
BC_0511	COG0069	glutamate synthase activity
BC_0511	COG0070	glutamate synthase
BC_0513	COG4555	ABC transporter
BC_0517	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC_0518	COG0735	belongs to the Fur family
BC_0541	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BC_0546	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC_0548	COG2766	serine protein kinase
BC_0555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC_0557	COG1585	Membrane protein implicated in regulation of membrane protease activity
BC_0558	COG2268	Band 7 protein
BC_0560	COG3290	protein histidine kinase activity
BC_0561	COG4565	transcriptional regulatory protein
BC_0562	COG2851	Citrate transporter
BC_0566	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC_0567	COG3842	ATPase activity
BC_0568	COG1175	transmembrane transport
BC_0569	COG0395	ABC-type sugar transport system, permease component
BC_0571	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC_0572	COG0745	RESPONSE REGULATOR receiver
BC_0573	COG5002	protein histidine kinase activity
BC_0575	COG4990	cell redox homeostasis
BC_0577	COG3290	protein histidine kinase activity
BC_0578	COG4565	transcriptional regulatory protein
BC_0579	COG3493	citrate carrier protein
BC_0580	COG0281	malic enzyme
BC_0582	COG0697	spore germination
BC_0583	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_0585	COG5002	protein histidine kinase activity
BC_0587	COG0456	acetyltransferase
BC_0587	COG0454	-acetyltransferase
BC_0588	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC_0589	COG3383	formate dehydrogenase (NAD+) activity
BC_0590	COG2427	Protein of unknown function (DUF1641)
BC_0593	COG0531	amino acid
BC_0595	COG0640	Transcriptional regulator
BC_0596	COG2217	Heavy metal translocating P-type atpase
BC_0597	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC_0602	COG3227	Zinc metalloprotease (Elastase)
BC_0606	COG2720	vancomycin resistance protein
BC_0607	COG1316	TRANSCRIPTIONal
BC_0608	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_0609	COG0346	lactoylglutathione lyase activity
BC_0610	COG1253	flavin adenine dinucleotide binding
BC_0611	COG1027	Aspartate ammonia-lyase
BC_0612	COG1620	l-lactate permease
BC_0615	COG3104	oligopeptide transport
BC_0616	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_0618	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_0622	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC_0624	COG4548	von Willebrand factor, type A
BC_0625	COG0714	Associated with various cellular activities
BC_0629	COG0531	amino acid
BC_0630	COG2188	Transcriptional regulator
BC_0631	COG1263	PTS System
BC_0631	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_0632	COG0366	Alpha amylase catalytic
BC_0635	COG0697	spore germination
BC_0637	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC_0638	COG1115	amino acid carrier protein
BC_0639	COG1126	abc transporter atp-binding protein
BC_0640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC_0641	COG0765	amino acid transport
BC_0642	COG0765	amino acid transport
BC_0643	COG0833	amino acid
BC_0649	COG2378	regulation of single-species biofilm formation
BC_0650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC_0651	COG5002	protein histidine kinase activity
BC_0654	COG0659	secondary active sulfate transmembrane transporter activity
BC_0656	COG2271	Major facilitator Superfamily
BC_0657	COG1846	Transcriptional regulator
BC_0658	COG0477	Major facilitator Superfamily
BC_0659	COG1609	Transcriptional regulator
BC_0660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC_0663	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC_0668	COG1063	alcohol dehydrogenase
BC_0678	COG0840	transmembrane signaling receptor activity
BC_0679	COG3584	3D domain protein
BC_0679	COG3583	domain protein
BC_0680	COG1476	TRANSCRIPTIONal
BC_0684	COG3104	oligopeptide transport
BC_0685	COG1114	Component of the transport system for branched-chain amino acids
BC_0688	COG1113	amino acid transport
BC_0689	COG2252	PERMEase
BC_0692	COG2153	protein acetylation
BC_0694	COG0569	domain protein
BC_0694	COG0475	glutathione-regulated potassium exporter activity
BC_0697	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC_0699	COG0833	amino acid
BC_0700	COG4990	cell redox homeostasis
BC_0703	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC_0705	COG0531	amino acid
BC_0707	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC_0708	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC_0709	COG1918	ferrous iron import across plasma membrane
BC_0709	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC_0710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC_0711	COG0573	inorganic phosphate transmembrane transporter activity
BC_0712	COG0581	inorganic phosphate transmembrane transporter activity
BC_0714	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC_0737	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BC_0742	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC_0743	COG1116	anion transmembrane transporter activity
BC_0744	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC_0745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC_0746	COG0352	thiamine-phosphate diphosphorylase activity
BC_0747	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC_0748	COG2104	thiamine diphosphate biosynthetic process
BC_0750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC_0751	COG0351	phosphomethylpyrimidine kinase
BC_0756	COG2205	protein histidine kinase activity
BC_0757	COG2814	Major facilitator Superfamily
BC_0758	COG1846	Transcriptional regulator
BC_0764	COG1136	(ABC) transporter
BC_0766	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC_0767	COG1129	ABC transporter
BC_0769	COG2252	PERMEase
BC_0770	COG1028	Short-chain dehydrogenase reductase Sdr
BC_0773	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC_0774	COG1621	beta-fructofuranosidase activity
BC_0775	COG1263	PTS System
BC_0775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_0776	COG1609	Transcriptional regulator
BC_0786	COG0778	Nitroreductase
BC_0787	COG2719	SpoVR family
BC_0789	COG3591	Belongs to the peptidase S1B family
BC_0791	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC_0792	COG1937	Protein conserved in bacteria
BC_0793	COG0425	Belongs to the sulfur carrier protein TusA family
BC_0793	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_0794	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_0794	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_0795	COG0425	Belongs to the sulfur carrier protein TusA family
BC_0796	COG0425	Belongs to the sulfur carrier protein TusA family
BC_0796	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_0797	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_0798	COG2210	Belongs to the sulfur carrier protein TusA family
BC_0799	COG0730	response to heat
BC_0801	COG1316	TRANSCRIPTIONal
BC_0802	COG0604	alcohol dehydrogenase
BC_0803	COG1283	sodium-dependent phosphate transmembrane transporter activity
BC_0806	COG3711	transcriptional antiterminator
BC_0806	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC_0807	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC_0808	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC_0813	COG1388	LysM domain
BC_0813	COG3584	3D domain protein
BC_0814	COG0577	efflux transmembrane transporter activity
BC_0815	COG1136	(ABC) transporter
BC_0817	COG5522	Integral membrane protein (intg_mem_TP0381)
BC_0820	COG1114	Component of the transport system for branched-chain amino acids
BC_0821	COG3546	catalase activity
BC_0828	COG0586	Pfam SNARE associated Golgi protein
BC_0838	COG0475	glutathione-regulated potassium exporter activity
BC_0840	COG1737	Transcriptional regulator
BC_0842	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_0842	COG1263	PTS System
BC_0844	COG2259	Doxx family
BC_0848	COG1522	sequence-specific DNA binding
BC_0849	COG0165	Argininosuccinate lyase
BC_0849	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BC_0850	COG1028	Short-chain dehydrogenase reductase Sdr
BC_0852	COG2076	Multidrug Resistance protein
BC_0854	COG1309	transcriptional regulator
BC_0855	COG2814	Major facilitator Superfamily
BC_0856	COG1733	regulation of RNA biosynthetic process
BC_0859	COG4533	DNA binding
BC_0860	COG2211	Major facilitator Superfamily
BC_0862	COG0693	protein deglycase activity
BC_0863	COG0753	catalase activity
BC_0863	COG0693	protein deglycase activity
BC_0865	COG0531	amino acid
BC_0866	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC_0868	COG1012	belongs to the aldehyde dehydrogenase family
BC_0870	COG1132	(ABC) transporter
BC_0871	COG1132	(ABC) transporter
BC_0872	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC_0873	COG0765	amino acid transport
BC_0874	COG1126	abc transporter atp-binding protein
BC_0877	COG0189	ligase activity
BC_0881	COG4585	Histidine kinase
BC_0882	COG2197	response regulator
BC_0883	COG0028	Belongs to the TPP enzyme family
BC_0884	COG3527	Alpha-acetolactate decarboxylase
BC_0886	COG0561	phosphatase activity
BC_0888	COG3409	Peptidoglycan-binding domain 1 protein
BC_0888	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC_0889	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC_0890	COG0318	PFAM AMP-dependent synthetase and ligase
BC_0893	COG0659	secondary active sulfate transmembrane transporter activity
BC_0894	COG2244	polysaccharide biosynthetic process
BC_0898	COG1024	Enoyl-CoA hydratase
BC_0901	COG1363	Peptidase, m42
BC_0908	COG0601	transmembrane transport
BC_0909	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC_0910	COG0444	Belongs to the ABC transporter superfamily
BC_0911	COG4608	Belongs to the ABC transporter superfamily
BC_0913	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_0935	COG0477	Major facilitator Superfamily
BC_0936	COG3290	protein histidine kinase activity
BC_0937	COG4565	transcriptional regulatory protein
BC_0938	COG3181	Tripartite tricarboxylate transporter family receptor
BC_0939	COG1401	restriction endodeoxyribonuclease activity
BC_0945	COG0582	viral genome integration into host DNA
BC_0953	COG0789	Transcriptional regulator
BC_0953	COG4978	Transcriptional regulator
BC_0956	COG0305	Participates in initiation and elongation during chromosome replication
BC_0962	COG0477	Major facilitator Superfamily
BC_0964	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_0968	COG1073	alpha beta
BC_0976	COG1183	phosphatidylcholine synthase activity
BC_0979	COG2376	Dihydroxyacetone kinase
BC_0981	COG2376	Dihydroxyacetone kinase
BC_0986	COG0457	Tetratricopeptide repeat
BC_0991	COG2373	Large extracellular alpha-helical protein
BC_0999	COG3237	CsbD-like
BC_1004	COG1191	sigma factor activity
BC_1006	COG2208	phosphoserine phosphatase activity
BC_1007	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC_1008	COG0784	Response regulator, receiver
BC_1008	COG5002	protein histidine kinase activity
BC_1008	COG2205	protein histidine kinase activity
BC_1012	COG0393	Putative heavy-metal-binding
BC_1015	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BC_1019	COG0420	3'-5' exonuclease activity
BC_1020	COG4717	serine-type aminopeptidase activity
BC_1023	COG1280	lysine exporter protein (LysE YggA)
BC_1024	COG0346	lactoylglutathione lyase activity
BC_1025	COG0346	lactoylglutathione lyase activity
BC_1026	COG0457	Tetratricopeptide repeat
BC_1027	COG2267	carboxylic ester hydrolase activity
BC_1031	COG2140	Oxalate decarboxylase
BC_1032	COG3620	sequence-specific DNA binding
BC_1033	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC_1034	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC_1036	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC_1037	COG1695	Transcriptional regulator
BC_1041	COG3973	AAA domain
BC_1048	COG4980	gas vesicle protein
BC_1049	COG0537	adenosine 5'-monophosphoramidase activity
BC_1050	COG1131	(ABC) transporter
BC_1051	COG4473	ABC transporter
BC_1055	COG3402	PFAM membrane-flanked domain
BC_1056	COG3428	Bacterial PH domain
BC_1063	COG0697	spore germination
BC_1064	COG3402	PFAM membrane-flanked domain
BC_1065	COG3428	Bacterial PH domain
BC_1066	COG2329	Antibiotic biosynthesis monooxygenase
BC_1067	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_1077	COG1309	transcriptional regulator
BC_1078	COG1511	domain protein
BC_1082	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_1083	COG1609	Transcriptional regulator
BC_1085	COG1234	tRNA 3'-trailer cleavage
BC_1086	COG0095	Lipoate-protein ligase
BC_1088	COG0318	PFAM AMP-dependent synthetase and ligase
BC_1090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BC_1091	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BC_1093	COG4208	sulfate ABC transporter
BC_1111	COG1408	metallophosphoesterase
BC_1112	COG1078	dGTPase activity
BC_1114	COG1595	DNA-templated transcription, initiation
BC_1115	COG3708	Transcriptional regulator
BC_1115	COG2207	Transcriptional regulator
BC_1118	COG2205	protein histidine kinase activity
BC_1119	COG0745	RESPONSE REGULATOR receiver
BC_1123	COG0501	Belongs to the peptidase M48B family
BC_1124	COG0840	transmembrane signaling receptor activity
BC_1125	COG3693	PFAM glycoside hydrolase, family 10
BC_1127	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC_1128	COG2224	Isocitrate lyase
BC_1131	COG1278	Cold shock
BC_1135	COG0398	Pfam SNARE associated Golgi protein
BC_1147	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC_1152	COG0367	asparagine synthase
BC_1153	COG0367	asparagine synthase
BC_1155	COG0753	catalase activity
BC_1156	COG0004	ammonium transporteR
BC_1160	COG2996	Protein conserved in bacteria
BC_1163	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_1165	COG0561	phosphatase activity
BC_1170	COG2267	carboxylic ester hydrolase activity
BC_1174	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC_1175	COG5504	Zn-dependent protease
BC_1179	COG4166	transmembrane transport
BC_1180	COG0601	transmembrane transport
BC_1181	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC_1182	COG0444	Belongs to the ABC transporter superfamily
BC_1183	COG4608	Belongs to the ABC transporter superfamily
BC_1184	COG0534	Mate efflux family protein
BC_1185	COG4166	transmembrane transport
BC_1188	COG1393	Belongs to the ArsC family
BC_1189	COG0861	Integral membrane protein TerC family
BC_1193	COG1164	Oligoendopeptidase f
BC_1195	COG2346	COG2346, Truncated hemoglobins
BC_1196	COG4116	CYTH
BC_1198	COG2357	RelA SpoT domain protein
BC_1200	COG0564	pseudouridine synthase activity
BC_1203	COG0772	Belongs to the SEDS family
BC_1204	COG1216	Glycosyl transferase, family 2
BC_1208	COG0457	Tetratricopeptide repeat
BC_1208	COG0463	Glycosyl transferase, family 2
BC_1212	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BC_1215	COG1091	dTDP-4-dehydrorhamnose reductase activity
BC_1224	COG2153	protein acetylation
BC_1226	COG2382	esterase
BC_1231	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC_1233	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC_1233	COG0512	Glutamine amidotransferase of anthranilate synthase
BC_1240	COG1620	l-lactate permease
BC_1241	COG5634	Uncharacterized conserved protein (DUF2278)
BC_1251	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC_1253	COG1476	TRANSCRIPTIONal
BC_1272	COG0582	viral genome integration into host DNA
BC_1277	COG1686	Belongs to the peptidase S11 family
BC_1278	COG0681	Belongs to the peptidase S26 family
BC_1285	COG1012	belongs to the aldehyde dehydrogenase family
BC_1287	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC_1288	COG1177	transmembrane transport
BC_1289	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BC_1291	COG2409	Drug exporters of the RND superfamily
BC_1293	COG0564	pseudouridine synthase activity
BC_1295	COG2340	Cysteine-rich secretory protein family
BC_1296	COG0247	lactate metabolic process
BC_1297	COG0277	FAD linked oxidase domain protein
BC_1298	COG3835	regulator
BC_1300	COG0745	RESPONSE REGULATOR receiver
BC_1301	COG5002	protein histidine kinase activity
BC_1302	COG2186	Transcriptional regulator
BC_1306	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BC_1308	COG2116	formate transmembrane transporter activity
BC_1309	COG0861	Integral membrane protein TerC family
BC_1310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC_1312	COG2030	dehydratase
BC_1317	COG1028	Short-chain dehydrogenase reductase Sdr
BC_1318	COG3243	poly(R)-hydroxyalkanoic acid synthase
BC_1320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC_1323	COG1840	ABC-type Fe3 transport system, periplasmic component
BC_1324	COG3842	ATPase activity
BC_1329	COG1349	DNA-binding transcription factor activity
BC_1334	COG2861	carbohydrate metabolic process
BC_1336	COG3852	Histidine kinase
BC_1337	COG1846	Transcriptional regulator
BC_1339	COG2318	DinB family
BC_1340	COG5002	protein histidine kinase activity
BC_1342	COG0720	synthase
BC_1345	COG4873	Protein conserved in bacteria
BC_1353	COG1780	Probably involved in ribonucleotide reductase function
BC_1354	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC_1355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC_1356	COG1725	Transcriptional regulator
BC_1357	COG1131	(ABC) transporter
BC_1359	COG1131	(ABC) transporter
BC_1361	COG1266	CAAX protease self-immunity
BC_1363	COG1522	sequence-specific DNA binding
BC_1365	COG1335	isochorismatase
BC_1367	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC_1368	COG2070	2-Nitropropane dioxygenase
BC_1369	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BC_1371	COG1696	Membrane protein involved in D-alanine export
BC_1376	COG0716	FMN binding
BC_1387	COG1846	Transcriptional regulator
BC_1389	COG1301	dicarboxylic acid transport
BC_1390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC_1391	COG4709	membrane
BC_1392	COG3874	Sporulation protein YtfJ
BC_1396	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC_1398	COG0440	acetolactate synthase activity
BC_1413	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC_1416	COG1183	phosphatidylcholine synthase activity
BC_1417	COG1368	sulfuric ester hydrolase activity
BC_1419	COG0019	diaminopimelate decarboxylase activity
BC_1423	COG0529	Catalyzes the synthesis of activated sulfate
BC_1424	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC_1428	COG1648	precorrin-2 dehydrogenase activity
BC_1430	COG0733	neurotransmitter:sodium symporter activity
BC_1434	COG1757	Na H antiporter
BC_1437	COG4758	membrane
BC_1438	COG4585	Histidine kinase
BC_1439	COG2197	response regulator
BC_1441	COG1114	Component of the transport system for branched-chain amino acids
BC_1452	COG0730	response to heat
BC_1453	COG0306	phosphate transporter
BC_1454	COG1392	Phosphate transport regulator
BC_1455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_1458	COG3852	Histidine kinase
BC_1459	COG1801	Protein of unknown function DUF72
BC_1461	COG0582	viral genome integration into host DNA
BC_1465	COG0392	lysyltransferase activity
BC_1465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BC_1468	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BC_1469	COG1686	Belongs to the peptidase S11 family
BC_1470	COG2715	membrane protein required for spore maturation
BC_1471	COG0700	Nucleoside recognition
BC_1472	COG1187	pseudouridine synthase activity
BC_1474	COG1333	cytochrome c biogenesis protein
BC_1475	COG1333	cytochrome c biogenesis protein
BC_1476	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC_1477	COG0745	RESPONSE REGULATOR receiver
BC_1478	COG5002	protein histidine kinase activity
BC_1479	COG2096	Adenosyltransferase
BC_1482	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BC_1483	COG1141	Ferredoxin
BC_1485	COG0514	ATP-dependent DNA helicase (RecQ)
BC_1486	COG1266	CAAX protease self-immunity
BC_1488	COG1408	metallophosphoesterase
BC_1489	COG0789	Transcriptional regulator
BC_1491	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC_1495	COG0492	ferredoxin-NADP+ reductase activity
BC_1496	COG0252	asparaginase activity
BC_1509	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC_1512	COG0142	geranyltranstransferase activity
BC_1514	COG0142	geranyltranstransferase activity
BC_1519	COG0457	Tetratricopeptide repeat
BC_1523	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC_1524	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC_1524	COG2010	Cytochrome c
BC_1525	COG4347	Protein of unknown function (DUF1405)
BC_1528	COG2738	Putative neutral zinc metallopeptidase
BC_1530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_1531	COG1694	Mazg nucleotide pyrophosphohydrolase
BC_1535	COG0438	transferase activity, transferring glycosyl groups
BC_1547	COG3935	DnaD domain protein
BC_1548	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC_1550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_1550	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC_1553	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC_1553	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_1563	COG0116	Belongs to the methyltransferase superfamily
BC_1565	COG1199	ATP-dependent helicase activity
BC_1566	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BC_1568	COG0024	Methionine aminopeptidase
BC_1570	COG2233	PERMEase
BC_1571	COG2311	Membrane
BC_1572	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC_1574	COG0456	acetyltransferase
BC_1582	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC_1584	COG3944	biosynthesis protein
BC_1586	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC_1589	COG1215	transferase activity, transferring glycosyl groups
BC_1590	COG0438	transferase activity, transferring glycosyl groups
BC_1593	COG0454	-acetyltransferase
BC_1597	COG0328	RNA-DNA hybrid ribonuclease activity
BC_1604	COG3403	YqcI/YcgG family
BC_1605	COG1280	lysine exporter protein (LysE YggA)
BC_1609	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC_1610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC_1612	COG0475	glutathione-regulated potassium exporter activity
BC_1613	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC_1614	COG4978	Transcriptional regulator
BC_1614	COG0789	Transcriptional regulator
BC_1616	COG2323	membrane
BC_1617	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BC_1623	COG1923	regulation of RNA biosynthetic process
BC_1625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC_1626	COG1360	Flagellar Motor Protein
BC_1627	COG2201	protein-glutamate methylesterase activity
BC_1628	COG2198	Histidine kinase
BC_1628	COG0643	Histidine kinase
BC_1629	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC_1629	COG1776	CheC inhibitor of MCP methylation
BC_1632	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC_1636	COG1256	bacterial-type flagellum assembly
BC_1637	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC_1638	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC_1641	COG1815	bacterial-type flagellum-dependent cell motility
BC_1642	COG1558	bacterial-type flagellum-dependent cell motility
BC_1643	COG1677	Flagellar hook-basal body complex protein FliE
BC_1644	COG1766	The M ring may be actively involved in energy transduction
BC_1645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC_1647	COG1157	protein secretion by the type III secretion system
BC_1654	COG0835	chemotaxis
BC_1654	COG0784	Response regulator, receiver
BC_1656	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC_1657	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC_1658	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC_1659	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC_1660	COG0741	lytic transglycosylase activity
BC_1662	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC_1663	COG1776	CheC inhibitor of MCP methylation
BC_1663	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC_1665	COG1338	Plays a role in the flagellum-specific transport system
BC_1666	COG1987	bacterial-type flagellum assembly
BC_1668	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC_1671	COG4786	Flagellar basal body rod
BC_1672	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC_1678	COG2329	Antibiotic biosynthesis monooxygenase
BC_1691	COG0406	alpha-ribazole phosphatase activity
BC_1697	COG0367	asparagine synthase
BC_1703	COG1802	Transcriptional regulator
BC_1704	COG0697	spore germination
BC_1705	COG0523	cobalamin synthesis protein
BC_1706	COG0701	Predicted permease
BC_1709	COG1757	Na H antiporter
BC_1710	COG0789	Transcriptional regulator
BC_1716	COG0534	Mate efflux family protein
BC_1717	COG3340	Belongs to the peptidase S51 family
BC_1721	COG0785	Cytochrome C biogenesis protein
BC_1726	COG2733	membrane
BC_1734	COG1131	(ABC) transporter
BC_1737	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC_1738	COG0528	UMP kinase activity
BC_1740	COG1027	Aspartate ammonia-lyase
BC_1741	COG0281	malic enzyme
BC_1742	COG4191	Histidine kinase
BC_1743	COG0784	Response regulator, receiver
BC_1744	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC_1753	COG2814	Major facilitator Superfamily
BC_1756	COG1695	Transcriptional regulator
BC_1759	COG0477	Major facilitator Superfamily
BC_1761	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC_1762	COG2223	nitrite transmembrane transporter activity
BC_1763	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC_1767	COG0733	neurotransmitter:sodium symporter activity
BC_1769	COG5566	PFAM Mor transcription activator
BC_1770	COG2323	membrane
BC_1774	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC_1776	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC_1777	COG0028	Belongs to the TPP enzyme family
BC_1781	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC_1786	COG2814	Major facilitator Superfamily
BC_1787	COG3384	dioxygenase
BC_1789	COG3279	Response regulator of the LytR AlgR family
BC_1790	COG0427	acetyl-CoA hydrolase
BC_1794	COG4166	transmembrane transport
BC_1799	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_1800	COG0745	RESPONSE REGULATOR receiver
BC_1803	COG1914	H( )-stimulated, divalent metal cation uptake system
BC_1806	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC_1807	COG0531	amino acid
BC_1812	COG2309	aminopeptidase activity
BC_1815	COG0456	acetyltransferase
BC_1818	COG1309	transcriptional regulator
BC_1819	COG2390	Transcriptional regulator
BC_1821	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_1822	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BC_1823	COG0295	cytidine deaminase activity
BC_1824	COG2963	transposase activity
BC_1825	COG2801	Transposase and inactivated derivatives
BC_1826	COG4846	Membrane protein involved in cytochrome C biogenesis
BC_1828	COG0006	proline dipeptidase activity
BC_1830	COG2132	Multicopper oxidase
BC_1836	COG1114	Component of the transport system for branched-chain amino acids
BC_1838	COG1276	copper resistance
BC_1838	COG2372	response to copper ion
BC_1839	COG4549	nuclear export factor GLE1
BC_1840	COG0697	spore germination
BC_1841	COG0583	DNA-binding transcription factor activity
BC_1842	COG1959	2 iron, 2 sulfur cluster binding
BC_1843	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC_1844	COG0778	Nitroreductase
BC_1846	COG0154	amidase activity
BC_1847	COG1396	sequence-specific DNA binding
BC_1864	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC_1864	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC_1884	COG2002	toxin-antitoxin pair type II binding
BC_1922	COG0154	amidase activity
BC_1923	COG0628	permease
BC_1925	COG1231	oxidoreductase activity
BC_1926	COG0523	cobalamin synthesis protein
BC_1928	COG0411	ABC transporter
BC_1932	COG0583	DNA-binding transcription factor activity
BC_1938	COG1271	oxidase subunit
BC_1939	COG1294	oxidase, subunit
BC_1940	COG4988	ABC transporter
BC_1941	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BC_1943	COG1216	Glycosyl transferase, family 2
BC_1951	COG1686	Belongs to the peptidase S11 family
BC_1953	COG0791	NLP P60 protein
BC_1953	COG1388	LysM domain
BC_1955	COG1132	(ABC) transporter
BC_1956	COG0745	RESPONSE REGULATOR receiver
BC_1957	COG5002	protein histidine kinase activity
BC_1958	COG0300	oxidoreductase activity
BC_1960	COG0726	polysaccharide deacetylase
BC_1964	COG0460	homoserine dehydrogenase
BC_1969	COG1316	TRANSCRIPTIONal
BC_1972	COG0745	RESPONSE REGULATOR receiver
BC_1973	COG5002	protein histidine kinase activity
BC_1974	COG0726	polysaccharide deacetylase
BC_1976	COG1285	pathogenesis
BC_1977	COG1247	-acetyltransferase
BC_1979	COG4264	IucA IucC family
BC_1980	COG0318	PFAM AMP-dependent synthetase and ligase
BC_1983	COG1082	Xylose isomerase domain protein TIM barrel
BC_1986	COG1279	arginine transmembrane transporter activity
BC_1987	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_1989	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC_1995	COG0577	efflux transmembrane transporter activity
BC_1996	COG2002	toxin-antitoxin pair type II binding
BC_1997	COG1404	Belongs to the peptidase S8 family
BC_1998	COG0640	Transcriptional regulator
BC_1999	COG0667	Aldo Keto reductase
BC_2001	COG3152	Membrane
BC_2006	COG0840	transmembrane signaling receptor activity
BC_2010	COG3949	Membrane
BC_2011	COG0783	Belongs to the Dps family
BC_2014	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC_2016	COG1231	oxidoreductase activity
BC_2017	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2018	COG4989	oxidoreductase activity
BC_2019	COG0523	cobalamin synthesis protein
BC_2020	COG0456	acetyltransferase
BC_2021	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC_2022	COG0702	epimerase
BC_2024	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC_2026	COG4166	transmembrane transport
BC_2031	COG5337	Spore coat protein CotH
BC_2032	COG1051	belongs to the nudix hydrolase family
BC_2033	COG0586	Pfam SNARE associated Golgi protein
BC_2034	COG2244	polysaccharide biosynthetic process
BC_2036	COG0701	Predicted permease
BC_2037	COG3689	TIGRFAM TIGR03943 family protein
BC_2038	COG1607	acyl-coa hydrolase
BC_2039	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC_2042	COG0702	epimerase
BC_2043	COG2839	Protein conserved in bacteria
BC_2044	COG1253	flavin adenine dinucleotide binding
BC_2047	COG1114	Component of the transport system for branched-chain amino acids
BC_2048	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC_2050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC_2052	COG1876	peptidase activity
BC_2054	COG0154	amidase activity
BC_2055	COG2211	Major facilitator Superfamily
BC_2058	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC_2060	COG0561	phosphatase activity
BC_2063	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC_2066	COG1819	glycosyl
BC_2067	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_2068	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_2074	COG0456	acetyltransferase
BC_2080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC_2095	COG3874	Sporulation protein YtfJ
BC_2100	COG2226	methyltransferase
BC_2104	COG1082	Xylose isomerase domain protein TIM barrel
BC_2105	COG0346	lactoylglutathione lyase activity
BC_2107	COG0604	alcohol dehydrogenase
BC_2108	COG1595	DNA-templated transcription, initiation
BC_2110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC_2114	COG0386	Belongs to the glutathione peroxidase family
BC_2115	COG1305	Transglutaminase-like
BC_2117	COG0714	Associated with various cellular activities
BC_2118	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BC_2119	COG1140	nitrate reductase beta subunit
BC_2120	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BC_2121	COG2181	nitrate reductase activity
BC_2122	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC_2123	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC_2124	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC_2125	COG0303	'Molybdopterin
BC_2126	COG0314	molybdopterin synthase activity
BC_2128	COG2223	nitrite transmembrane transporter activity
BC_2132	COG1648	precorrin-2 dehydrogenase activity
BC_2134	COG1587	Uroporphyrinogen-III synthase
BC_2134	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC_2135	COG2146	nitrite reductase [NAD(P)H] activity
BC_2136	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC_2137	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BC_2142	COG2359	stage V sporulation protein S
BC_2147	COG0457	Tetratricopeptide repeat
BC_2150	COG1418	mRNA catabolic process
BC_2151	COG0488	(ABC) transporter
BC_2154	COG0629	single-stranded DNA binding
BC_2155	COG1413	lyase activity
BC_2158	COG2136	Putative SAM-dependent methyltransferase
BC_2158	COG2521	methyltransferase
BC_2169	COG0017	Asparaginyl-tRNA synthetase
BC_2170	COG0733	neurotransmitter:sodium symporter activity
BC_2175	COG2610	gluconate transmembrane transporter activity
BC_2177	COG1794	racemase activity, acting on amino acids and derivatives
BC_2179	COG0456	acetyltransferase
BC_2181	COG3655	Transcriptional regulator
BC_2182	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC_2184	COG1131	(ABC) transporter
BC_2185	COG4473	ABC transporter
BC_2187	COG0546	phosphoglycolate phosphatase activity
BC_2190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC_2193	COG0768	penicillin binding
BC_2195	COG0204	Acyl-transferase
BC_2196	COG1272	protein, Hemolysin III
BC_2198	COG0805	protein transport
BC_2200	COG1307	EDD domain protein, DegV family
BC_2202	COG1999	signal sequence binding
BC_2203	COG0071	Belongs to the small heat shock protein (HSP20) family
BC_2204	COG0367	asparagine synthase
BC_2207	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC_2208	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_2209	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC_2213	COG1335	isochorismatase
BC_2215	COG0668	transmembrane transport
BC_2216	COG4585	Histidine kinase
BC_2216	COG2203	Gaf domain
BC_2217	COG2197	response regulator
BC_2218	COG1737	Transcriptional regulator
BC_2219	COG0384	phenazine biosynthesis protein PhzF
BC_2220	COG1064	alcohol dehydrogenase
BC_2225	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC_2232	COG0517	IMP dehydrogenase activity
BC_2232	COG1125	glycine betaine transport
BC_2233	COG1174	glycine betaine transport
BC_2240	COG1253	flavin adenine dinucleotide binding
BC_2241	COG1012	belongs to the aldehyde dehydrogenase family
BC_2242	COG5506	Protein of unknown function (DUF1694)
BC_2245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC_2246	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BC_2247	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC_2248	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC_2249	COG0456	acetyltransferase
BC_2250	COG3829	transcription factor binding
BC_2251	COG1509	lysine 2,3-aminomutase activity
BC_2258	COG4991	sh3 domain protein
BC_2258	COG0515	serine threonine protein kinase
BC_2258	COG3064	Membrane
BC_2260	COG0671	phosphoesterase, PA-phosphatase related
BC_2261	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC_2262	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC_2278	COG0300	oxidoreductase activity
BC_2281	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_2281	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC_2283	COG2814	Major facilitator Superfamily
BC_2284	COG4841	protein insertion into membrane
BC_2285	COG0372	Belongs to the citrate synthase family
BC_2286	COG2079	MmgE PrpD family protein
BC_2287	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC_2288	COG1960	acyl-CoA dehydrogenase activity
BC_2289	COG2084	Dehydrogenase
BC_2291	COG1280	lysine exporter protein (LysE YggA)
BC_2292	COG1024	Enoyl-CoA hydratase
BC_2295	COG0420	3'-5' exonuclease activity
BC_2296	COG0419	ATPase involved in DNA repair
BC_2300	COG2223	nitrite transmembrane transporter activity
BC_2302	COG1028	Short-chain dehydrogenase reductase Sdr
BC_2303	COG1169	isochorismate synthase
BC_2304	COG1021	2,3-dihydroxybenzoate-AMP ligase
BC_2305	COG1535	isochorismatase
BC_2305	COG3433	isochorismatase activity
BC_2306	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC_2307	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC_2308	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC_2309	COG3251	PFAM MbtH domain protein
BC_2310	COG2814	Major facilitator Superfamily
BC_2313	COG0776	regulation of translation
BC_2315	COG2318	DinB family
BC_2317	COG1115	amino acid carrier protein
BC_2321	COG1187	pseudouridine synthase activity
BC_2322	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC_2323	COG1136	(ABC) transporter
BC_2325	COG2814	Major facilitator Superfamily
BC_2328	COG0028	Belongs to the TPP enzyme family
BC_2335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC_2339	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_2342	COG2801	Transposase and inactivated derivatives
BC_2343	COG2963	transposase activity
BC_2349	COG1247	-acetyltransferase
BC_2356	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2362	COG0583	DNA-binding transcription factor activity
BC_2363	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC_2367	COG0583	DNA-binding transcription factor activity
BC_2368	COG2258	MOSC domain
BC_2371	COG1132	(ABC) transporter
BC_2372	COG1132	(ABC) transporter
BC_2379	COG1396	sequence-specific DNA binding
BC_2385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC_2386	COG1595	DNA-templated transcription, initiation
BC_2392	COG1649	PFAM Uncharacterised BCR, COG1649
BC_2397	COG2971	BadF BadG BcrA BcrD
BC_2399	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC_2401	COG1846	Transcriptional regulator
BC_2406	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_2410	COG1309	transcriptional regulator
BC_2421	COG0582	viral genome integration into host DNA
BC_2430	COG0500	methyltransferase
BC_2430	COG3615	Tellurite resistance protein tehB
BC_2432	COG2226	methyltransferase
BC_2433	COG3961	Belongs to the TPP enzyme family
BC_2434	COG1846	Transcriptional regulator
BC_2439	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC_2444	COG2002	toxin-antitoxin pair type II binding
BC_2446	COG0730	response to heat
BC_2447	COG0110	maltose O-acetyltransferase activity
BC_2448	COG1686	Belongs to the peptidase S11 family
BC_2450	COG2814	Major facilitator Superfamily
BC_2451	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC_2460	COG2312	Erythromycin esterase
BC_2461	COG0741	lytic transglycosylase activity
BC_2462	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2467	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC_2468	COG0768	penicillin binding
BC_2469	COG1595	DNA-templated transcription, initiation
BC_2471	COG0768	penicillin binding
BC_2474	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2476	COG1408	metallophosphoesterase
BC_2478	COG1131	(ABC) transporter
BC_2480	COG1309	transcriptional regulator
BC_2484	COG0439	Biotin carboxylase
BC_2485	COG0511	ligase activity, forming carbon-carbon bonds
BC_2486	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC_2487	COG1024	Enoyl-CoA hydratase
BC_2488	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC_2489	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC_2490	COG2963	transposase activity
BC_2491	COG2801	Transposase and inactivated derivatives
BC_2496	COG1686	Belongs to the peptidase S11 family
BC_2503	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC_2506	COG3227	Zinc metalloprotease (Elastase)
BC_2507	COG2207	Transcriptional regulator
BC_2513	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC_2515	COG2814	Major facilitator Superfamily
BC_2516	COG1028	Short-chain dehydrogenase reductase Sdr
BC_2517	COG1733	regulation of RNA biosynthetic process
BC_2526	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_2529	COG1063	alcohol dehydrogenase
BC_2531	COG2323	membrane
BC_2532	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BC_2534	COG3386	PFAM SMP-30 Gluconolaconase
BC_2535	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BC_2536	COG3773	Cell wall hydrolase
BC_2538	COG0745	RESPONSE REGULATOR receiver
BC_2539	COG2205	protein histidine kinase activity
BC_2543	COG1136	(ABC) transporter
BC_2544	COG0577	efflux transmembrane transporter activity
BC_2548	COG0460	homoserine dehydrogenase
BC_2549	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_2551	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC_2556	COG0582	viral genome integration into host DNA
BC_2575	COG0582	viral genome integration into host DNA
BC_2599	COG4824	toxin secretion phage lysis holin
BC_2609	COG2124	cytochrome p450
BC_2613	COG2124	cytochrome p450
BC_2618	COG0561	phosphatase activity
BC_2619	COG5002	protein histidine kinase activity
BC_2622	COG1819	glycosyl
BC_2623	COG1794	racemase activity, acting on amino acids and derivatives
BC_2629	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC_2632	COG2207	Transcriptional regulator
BC_2632	COG3708	Transcriptional regulator
BC_2640	COG1335	isochorismatase
BC_2643	COG0546	phosphoglycolate phosphatase activity
BC_2645	COG0519	Catalyzes the synthesis of GMP from XMP
BC_2646	COG3344	reverse transcriptase
BC_2660	COG0604	alcohol dehydrogenase
BC_2661	COG0671	phosphoesterase, PA-phosphatase related
BC_2671	COG0693	protein deglycase activity
BC_2673	COG2814	Major facilitator Superfamily
BC_2676	COG0584	glycerophosphoryl diester phosphodiesterase
BC_2680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_2681	COG0697	spore germination
BC_2689	COG2223	nitrite transmembrane transporter activity
BC_2693	COG0592	DNA-directed DNA polymerase activity
BC_2697	COG0251	oxidation-reduction process
BC_2698	COG3878	Protein conserved in bacteria
BC_2704	COG4667	esterase of the alpha-beta hydrolase superfamily
BC_2713	COG0322	excinuclease ABC activity
BC_2719	COG1131	(ABC) transporter
BC_2723	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC_2733	COG1073	alpha beta
BC_2734	COG1523	belongs to the glycosyl hydrolase 13 family
BC_2735	COG3227	Zinc metalloprotease (Elastase)
BC_2740	COG0201	protein transport
BC_2741	COG0697	spore germination
BC_2742	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_2743	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC_2749	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2752	COG2959	enzyme of heme biosynthesis
BC_2753	COG3773	Cell wall hydrolase
BC_2753	COG3409	Peptidoglycan-binding domain 1 protein
BC_2760	COG1309	transcriptional regulator
BC_2766	COG3284	Transcriptional regulator
BC_2770	COG1349	DNA-binding transcription factor activity
BC_2773	COG1959	2 iron, 2 sulfur cluster binding
BC_2776	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC_2777	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC_2778	COG0022	dehydrogenase e1 component
BC_2779	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC_2781	COG1028	Short-chain dehydrogenase reductase Sdr
BC_2782	COG0456	acetyltransferase
BC_2782	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC_2790	COG4176	ABC-type proline glycine betaine transport system permease component
BC_2791	COG0517	IMP dehydrogenase activity
BC_2791	COG4175	Glycine betaine
BC_2797	COG2153	protein acetylation
BC_2798	COG3397	chitin binding
BC_2799	COG1819	glycosyl
BC_2802	COG2205	protein histidine kinase activity
BC_2803	COG2226	methyltransferase
BC_2804	COG2315	Protein conserved in bacteria
BC_2815	COG0514	ATP-dependent DNA helicase (RecQ)
BC_2821	COG2801	Transposase and inactivated derivatives
BC_2824	COG4637	Psort location Cytoplasmic, score
BC_2827	COG3397	chitin binding
BC_2830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC_2831	COG1115	amino acid carrier protein
BC_2832	COG1012	belongs to the aldehyde dehydrogenase family
BC_2833	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC_2835	COG3938	Belongs to the proline racemase family
BC_2836	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC_2846	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BC_2848	COG4166	transmembrane transport
BC_2850	COG4948	Mandelate Racemase Muconate Lactonizing
BC_2853	COG0667	Aldo Keto reductase
BC_2863	COG3850	Histidine kinase
BC_2863	COG5002	protein histidine kinase activity
BC_2864	COG0745	RESPONSE REGULATOR receiver
BC_2870	COG1164	Oligoendopeptidase f
BC_2871	COG1307	EDD domain protein, DegV family
BC_2880	COG2814	Major facilitator Superfamily
BC_2882	COG1664	Polymer-forming cytoskeletal
BC_2883	COG0789	Transcriptional regulator
BC_2884	COG4533	DNA binding
BC_2885	COG0477	Major facilitator Superfamily
BC_2885	COG2814	Major facilitator Superfamily
BC_2888	COG2261	transglycosylase associated protein
BC_2891	COG2226	methyltransferase
BC_2896	COG0436	Aminotransferase
BC_2897	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BC_2902	COG1131	(ABC) transporter
BC_2907	COG0628	permease
BC_2909	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC_2910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC_2911	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC_2919	COG2746	aminoglycoside 3-N-acetyltransferase activity
BC_2921	COG0697	spore germination
BC_2922	COG2318	DinB family
BC_2926	COG4912	Dna alkylation repair
BC_2927	COG0346	lactoylglutathione lyase activity
BC_2928	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_2929	COG0726	polysaccharide deacetylase
BC_2931	COG0861	Integral membrane protein TerC family
BC_2932	COG1368	sulfuric ester hydrolase activity
BC_2933	COG0488	(ABC) transporter
BC_2936	COG1309	transcriptional regulator
BC_2939	COG0287	Prephenate dehydrogenase
BC_2942	COG1605	Chorismate mutase
BC_2942	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC_2952	COG3584	3D domain protein
BC_2952	COG1388	LysM domain
BC_2954	COG0346	lactoylglutathione lyase activity
BC_2960	COG1879	ABC-type sugar transport system periplasmic component
BC_2961	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC_2962	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC_2964	COG2390	Transcriptional regulator
BC_2965	COG1070	Carbohydrate kinase
BC_2969	COG2329	Antibiotic biosynthesis monooxygenase
BC_2973	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_2977	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC_2978	COG4187	Peptidase family M20/M25/M40
BC_2979	COG1414	Transcriptional regulator
BC_2980	COG0833	amino acid
BC_2983	COG3239	Fatty acid desaturase
BC_2985	COG2720	vancomycin resistance protein
BC_2986	COG1785	Belongs to the alkaline phosphatase family
BC_2988	COG3655	Transcriptional regulator
BC_2992	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_2993	COG0346	lactoylglutathione lyase activity
BC_2997	COG0714	Associated with various cellular activities
BC_3001	COG0463	Glycosyl transferase, family 2
BC_3007	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC_3008	COG0753	catalase activity
BC_3018	COG0714	Associated with various cellular activities
BC_3024	COG0778	Nitroreductase
BC_3025	COG1846	Transcriptional regulator
BC_3034	COG0037	tRNA processing
BC_3034	COG0590	tRNA wobble adenosine to inosine editing
BC_3035	COG0456	acetyltransferase
BC_3039	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_3042	COG0642	Histidine kinase
BC_3043	COG0745	RESPONSE REGULATOR receiver
BC_3044	COG0596	Alpha beta hydrolase
BC_3050	COG0730	response to heat
BC_3052	COG0833	amino acid
BC_3054	COG4335	DNA alkylation repair
BC_3067	COG1984	allophanate hydrolase subunit 2
BC_3068	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC_3069	COG1414	Transcriptional regulator
BC_3071	COG3142	Participates in the control of copper homeostasis
BC_3072	COG0640	Transcriptional regulator
BC_3081	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BC_3087	COG0574	Belongs to the PEP-utilizing enzyme family
BC_3087	COG3848	Pyruvate phosphate dikinase
BC_3088	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_3092	COG1063	alcohol dehydrogenase
BC_3093	COG1027	Aspartate ammonia-lyase
BC_3094	COG0252	asparaginase activity
BC_3095	COG1396	sequence-specific DNA binding
BC_3100	COG5002	protein histidine kinase activity
BC_3105	COG2207	Transcriptional regulator
BC_3107	COG0322	excinuclease ABC activity
BC_3108	COG0531	amino acid
BC_3109	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC_3111	COG0531	amino acid
BC_3113	COG0784	Response regulator, receiver
BC_3114	COG4191	Histidine kinase
BC_3116	COG1115	amino acid carrier protein
BC_3118	COG2124	cytochrome p450
BC_3121	COG0737	Belongs to the 5'-nucleotidase family
BC_3122	COG2267	carboxylic ester hydrolase activity
BC_3123	COG1335	isochorismatase
BC_3127	COG0583	DNA-binding transcription factor activity
BC_3128	COG1846	Transcriptional regulator
BC_3129	COG0598	Magnesium transport protein CorA
BC_3133	COG1073	alpha beta
BC_3137	COG0415	Belongs to the DNA photolyase family
BC_3140	COG0288	reversible hydration of carbon dioxide
BC_3142	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC_3143	COG5609	conserved protein (DUF2294)
BC_3144	COG5609	conserved protein (DUF2294)
BC_3149	COG1575	Belongs to the MenA family. Type 1 subfamily
BC_3151	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_3153	COG0798	PFAM Bile acid sodium symporter
BC_3154	COG0346	lactoylglutathione lyase activity
BC_3155	COG0640	Transcriptional regulator
BC_3158	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC_3159	COG3320	Male sterility
BC_3159	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC_3162	COG2814	Major facilitator Superfamily
BC_3163	COG1309	transcriptional regulator
BC_3164	COG2068	MobA-Related Protein
BC_3165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BC_3174	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3175	COG1522	sequence-specific DNA binding
BC_3178	COG0346	lactoylglutathione lyase activity
BC_3189	COG0814	amino acid
BC_3190	COG0583	DNA-binding transcription factor activity
BC_3191	COG0697	spore germination
BC_3200	COG0745	RESPONSE REGULATOR receiver
BC_3201	COG5002	protein histidine kinase activity
BC_3201	COG3850	Histidine kinase
BC_3212	COG2814	Major facilitator Superfamily
BC_3216	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC_3219	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC_3223	COG0577	efflux transmembrane transporter activity
BC_3227	COG5002	protein histidine kinase activity
BC_3227	COG3850	Histidine kinase
BC_3229	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_3231	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC_3233	COG0738	Major facilitator superfamily
BC_3235	COG0738	Major facilitator superfamily
BC_3241	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BC_3243	COG1335	isochorismatase
BC_3244	COG1522	sequence-specific DNA binding
BC_3245	COG0531	amino acid
BC_3248	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC_3252	COG0662	Cupin 2, conserved barrel domain protein
BC_3253	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_3253	COG2207	Transcriptional regulator
BC_3257	COG3409	Peptidoglycan-binding domain 1 protein
BC_3257	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC_3294	COG5444	nuclease activity
BC_3307	COG1876	peptidase activity
BC_3308	COG2843	Capsule synthesis protein
BC_3310	COG0477	Major facilitator Superfamily
BC_3313	COG1846	Transcriptional regulator
BC_3314	COG2814	Major facilitator Superfamily
BC_3316	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BC_3320	COG1733	regulation of RNA biosynthetic process
BC_3321	COG0778	Nitroreductase
BC_3327	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3329	COG1131	(ABC) transporter
BC_3334	COG1011	Hydrolase
BC_3340	COG0180	Tryptophanyl-tRNA synthetase
BC_3342	COG0628	permease
BC_3347	COG0500	methyltransferase
BC_3349	COG0477	Major facilitator Superfamily
BC_3355	COG1253	flavin adenine dinucleotide binding
BC_3356	COG0789	Transcriptional regulator
BC_3358	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC_3364	COG0697	spore germination
BC_3366	COG1357	PFAM Pentapeptide repeats (8 copies)
BC_3367	COG3813	Protein conserved in bacteria
BC_3368	COG2706	6-phosphogluconolactonase activity
BC_3369	COG1070	Carbohydrate kinase
BC_3372	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC_3377	COG0604	alcohol dehydrogenase
BC_3378	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC_3382	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3385	COG0840	transmembrane signaling receptor activity
BC_3387	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC_3387	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC_3388	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC_3388	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC_3389	COG1733	regulation of RNA biosynthetic process
BC_3392	COG0656	L-ascorbic acid biosynthetic process
BC_3393	COG2814	Major facilitator Superfamily
BC_3398	COG0814	amino acid
BC_3404	COG1733	regulation of RNA biosynthetic process
BC_3405	COG2188	Transcriptional regulator
BC_3406	COG0673	inositol 2-dehydrogenase activity
BC_3407	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC_3408	COG1733	regulation of RNA biosynthetic process
BC_3409	COG1733	regulation of RNA biosynthetic process
BC_3414	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_3418	COG0384	phenazine biosynthesis protein PhzF
BC_3419	COG0318	PFAM AMP-dependent synthetase and ligase
BC_3420	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC_3421	COG1733	regulation of RNA biosynthetic process
BC_3426	COG1191	sigma factor activity
BC_3428	COG1280	lysine exporter protein (LysE YggA)
BC_3439	COG1151	hydroxylamine reductase activity
BC_3441	COG3757	hydrolase, family 25
BC_3441	COG3409	Peptidoglycan-binding domain 1 protein
BC_3447	COG2072	flavoprotein involved in K transport
BC_3455	COG1113	amino acid transport
BC_3456	COG2814	Major facilitator Superfamily
BC_3462	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC_3463	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC_3465	COG1247	-acetyltransferase
BC_3466	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_3467	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_3468	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_3469	COG3739	integral membrane protein
BC_3473	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_3476	COG0583	DNA-binding transcription factor activity
BC_3483	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BC_3484	COG1164	Oligoendopeptidase f
BC_3490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC_3495	COG0584	glycerophosphoryl diester phosphodiesterase
BC_3497	COG0640	Transcriptional regulator
BC_3498	COG0604	alcohol dehydrogenase
BC_3501	COG0457	Tetratricopeptide repeat
BC_3504	COG0277	FAD linked oxidase domain protein
BC_3509	COG1183	phosphatidylcholine synthase activity
BC_3511	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_3511	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_3512	COG1252	NADH dehydrogenase
BC_3514	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC_3516	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC_3518	COG0457	Tetratricopeptide repeat
BC_3522	COG1309	transcriptional regulator
BC_3528	COG3852	Histidine kinase
BC_3530	COG1285	pathogenesis
BC_3532	COG2514	catechol 2,3-dioxygenase activity
BC_3533	COG2720	vancomycin resistance protein
BC_3539	COG1278	Cold shock
BC_3541	COG0716	FMN binding
BC_3543	COG0494	nUDIX hydrolase
BC_3548	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3550	COG0165	Argininosuccinate lyase
BC_3553	COG4145	pantothenate transmembrane transporter activity
BC_3555	COG1012	belongs to the aldehyde dehydrogenase family
BC_3556	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3557	COG1657	PFAM Prenyltransferase squalene oxidase
BC_3558	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BC_3559	COG2962	Rard protein
BC_3560	COG3326	Membrane
BC_3563	COG0489	protein tyrosine kinase activity
BC_3565	COG0314	molybdopterin synthase activity
BC_3566	COG0303	'Molybdopterin
BC_3568	COG2116	formate transmembrane transporter activity
BC_3570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC_3571	COG5609	conserved protein (DUF2294)
BC_3572	COG2427	Protein of unknown function (DUF1641)
BC_3573	COG3383	formate dehydrogenase (NAD+) activity
BC_3574	COG0697	spore germination
BC_3577	COG0531	amino acid
BC_3583	COG2226	methyltransferase
BC_3584	COG4166	transmembrane transport
BC_3585	COG4166	transmembrane transport
BC_3586	COG4166	transmembrane transport
BC_3587	COG1316	TRANSCRIPTIONal
BC_3589	COG1595	DNA-templated transcription, initiation
BC_3591	COG1131	(ABC) transporter
BC_3595	COG0673	inositol 2-dehydrogenase activity
BC_3596	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC_3597	COG0187	DNA topoisomerase II activity
BC_3599	COG1832	CoA-binding protein
BC_3600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC_3601	COG0745	RESPONSE REGULATOR receiver
BC_3605	COG4841	protein insertion into membrane
BC_3606	COG0824	Thioesterase
BC_3612	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC_3616	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC_3618	COG0726	polysaccharide deacetylase
BC_3622	COG2211	Major facilitator Superfamily
BC_3627	COG0183	Belongs to the thiolase family
BC_3628	COG0318	PFAM AMP-dependent synthetase and ligase
BC_3629	COG1268	BioY protein
BC_3630	COG0318	PFAM AMP-dependent synthetase and ligase
BC_3631	COG0318	PFAM AMP-dependent synthetase and ligase
BC_3639	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_3641	COG5002	protein histidine kinase activity
BC_3642	COG0400	carboxylic ester hydrolase activity
BC_3643	COG0346	lactoylglutathione lyase activity
BC_3644	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC_3646	COG0069	glutamate synthase activity
BC_3647	COG1902	pentaerythritol trinitrate reductase activity
BC_3648	COG1329	Transcriptional regulator
BC_3661	COG4846	Membrane protein involved in cytochrome C biogenesis
BC_3662	COG0785	Cytochrome C biogenesis protein
BC_3666	COG1131	(ABC) transporter
BC_3668	COG0583	DNA-binding transcription factor activity
BC_3670	COG1346	cytolysis
BC_3673	COG0730	response to heat
BC_3678	COG1132	(ABC) transporter
BC_3679	COG1132	(ABC) transporter
BC_3684	COG3639	organic phosphonate transmembrane transporter activity
BC_3686	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC_3687	COG0737	Belongs to the 5'-nucleotidase family
BC_3689	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC_3693	COG1695	Transcriptional regulator
BC_3694	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC_3698	COG0739	heme binding
BC_3698	COG0741	lytic transglycosylase activity
BC_3698	COG1196	nuclear chromosome segregation
BC_3699	COG0741	lytic transglycosylase activity
BC_3706	COG0789	Transcriptional regulator
BC_3707	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BC_3708	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC_3709	COG2860	membrane
BC_3718	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC_3718	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC_3718	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC_3719	COG1105	Belongs to the carbohydrate kinase PfkB family
BC_3720	COG1349	DNA-binding transcription factor activity
BC_3721	COG1979	alcohol dehydrogenase
BC_3722	COG2322	membrane
BC_3724	COG1113	amino acid transport
BC_3726	COG1408	metallophosphoesterase
BC_3727	COG2116	formate transmembrane transporter activity
BC_3730	COG2217	Heavy metal translocating P-type atpase
BC_3731	COG2608	mercury ion transmembrane transporter activity
BC_3732	COG1937	Protein conserved in bacteria
BC_3734	COG2819	hydrolase of the alpha beta superfamily
BC_3735	COG1120	ATPase activity
BC_3736	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_3737	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_3738	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_3739	COG0708	Exodeoxyribonuclease III
BC_3740	COG2169	Transcriptional regulator
BC_3741	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC_3742	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BC_3746	COG2267	carboxylic ester hydrolase activity
BC_3747	COG5001	Diguanylate cyclase
BC_3747	COG3300	MHYT domain
BC_3750	COG1086	Polysaccharide biosynthesis protein
BC_3754	COG1346	cytolysis
BC_3756	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC_3759	COG2723	6-phospho-beta-galactosidase activity
BC_3760	COG2723	6-phospho-beta-galactosidase activity
BC_3762	COG1404	Belongs to the peptidase S8 family
BC_3765	COG1368	sulfuric ester hydrolase activity
BC_3766	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC_3771	COG4550	Control of competence regulator ComK, YlbF/YmcA
BC_3773	COG1013	pyruvate-flavodoxin oxidoreductase activity
BC_3774	COG0674	pyruvate-flavodoxin oxidoreductase activity
BC_3774	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BC_3776	COG2359	stage V sporulation protein S
BC_3777	COG1692	metallophosphoesterase
BC_3781	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC_3782	COG1426	Protein conserved in bacteria
BC_3785	COG0300	oxidoreductase activity
BC_3786	COG0612	Peptidase, M16
BC_3787	COG0612	Peptidase, M16
BC_3792	COG2188	Transcriptional regulator
BC_3795	COG0740	serine-type endopeptidase activity
BC_3796	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC_3798	COG0527	aspartate kinase activity
BC_3799	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC_3800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC_3801	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC_3802	COG1873	PFAM PRC-barrel domain
BC_3803	COG0612	Peptidase, M16
BC_3804	COG0726	polysaccharide deacetylase
BC_3807	COG0196	riboflavin kinase activity
BC_3810	COG1550	Protein conserved in bacteria
BC_3812	COG1358	cellular component organization or biogenesis
BC_3813	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BC_3814	COG0195	Participates in both transcription termination and antitermination
BC_3820	COG4589	Belongs to the CDS family
BC_3829	COG4974	Belongs to the 'phage' integrase family
BC_3831	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC_3832	COG0758	DNA mediated transformation
BC_3833	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC_3841	COG1837	Belongs to the UPF0109 family
BC_3843	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC_3845	COG0552	protein localization to endoplasmic reticulum
BC_3846	COG1196	nuclear chromosome segregation
BC_3849	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BC_3853	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC_3854	COG1461	Dihydroxyacetone kinase
BC_3855	COG1302	Protein conserved in bacteria
BC_3857	COG1564	THIamine pyrophosphokinase
BC_3858	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC_3860	COG0515	serine threonine protein kinase
BC_3860	COG2815	serine threonine protein kinase
BC_3861	COG0631	protein serine/threonine phosphatase activity
BC_3863	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC_3863	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC_3866	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC_3867	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC_3871	COG1561	YicC-like family, N-terminal region
BC_3875	COG0006	proline dipeptidase activity
BC_3879	COG3069	C4-dicarboxylate transmembrane transporter activity
BC_3892	COG0564	pseudouridine synthase activity
BC_3896	COG3599	regulation of cell shape
BC_3897	COG2302	S4 RNA-binding domain
BC_3898	COG0762	integral membrane protein
BC_3900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC_3902	COG1873	PFAM PRC-barrel domain
BC_3903	COG1191	sigma factor activity
BC_3904	COG1191	sigma factor activity
BC_3906	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC_3907	COG0849	cell division
BC_3911	COG0772	Belongs to the SEDS family
BC_3915	COG0768	penicillin binding
BC_3920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC_3924	COG1399	metal-binding, possibly nucleic acid-binding protein
BC_3926	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC_3927	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC_3928	COG3314	Sporulation integral membrane protein YlbJ
BC_3930	COG0742	ribosomal rna small subunit methyltransferase
BC_3933	COG3679	Belongs to the UPF0342 family
BC_3934	COG0406	alpha-ribazole phosphatase activity
BC_3937	COG2340	Cysteine-rich secretory protein family
BC_3940	COG3336	cytochrome c oxidase
BC_3947	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC_3948	COG0772	Belongs to the SEDS family
BC_3950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC_3951	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC_3953	COG4896	Protein conserved in bacteria
BC_3958	COG0483	inositol monophosphate 1-phosphatase activity
BC_3972	COG0022	dehydrogenase e1 component
BC_3973	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC_3975	COG0561	phosphatase activity
BC_3977	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC_3978	COG0569	domain protein
BC_3982	COG0583	DNA-binding transcription factor activity
BC_3983	COG0517	IMP dehydrogenase activity
BC_3985	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BC_3986	COG4703	Protein of unknown function (DUF1797)
BC_3989	COG2200	EAL domain
BC_3990	COG1028	Short-chain dehydrogenase reductase Sdr
BC_3991	COG1408	metallophosphoesterase
BC_4000	COG2814	Major facilitator Superfamily
BC_4005	COG3209	COG3209 Rhs family protein
BC_4007	COG2205	protein histidine kinase activity
BC_4009	COG0436	Aminotransferase
BC_4010	COG1609	Transcriptional regulator
BC_4011	COG3833	ABC-type maltose transport systems, permease component
BC_4012	COG1175	transmembrane transport
BC_4015	COG0366	Alpha amylase catalytic
BC_4016	COG3842	ATPase activity
BC_4023	COG0183	Belongs to the thiolase family
BC_4029	COG1695	Transcriptional regulator
BC_4030	COG1028	Short-chain dehydrogenase reductase Sdr
BC_4034	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC_4035	COG0436	Aminotransferase
BC_4042	COG2084	Dehydrogenase
BC_4044	COG2199	diguanylate cyclase activity
BC_4044	COG2203	Gaf domain
BC_4045	COG0778	Nitroreductase
BC_4050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC_4050	COG1263	PTS System
BC_4050	COG2190	(PTS) system
BC_4051	COG3711	transcriptional antiterminator
BC_4055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC_4059	COG1547	Domain of unknown function (DUF309)
BC_4060	COG0456	acetyltransferase
BC_4061	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC_4062	COG4086	secreted protein
BC_4063	COG0561	phosphatase activity
BC_4064	COG0697	spore germination
BC_4067	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC_4071	COG0733	neurotransmitter:sodium symporter activity
BC_4075	COG1686	Belongs to the peptidase S11 family
BC_4076	COG1725	Transcriptional regulator
BC_4077	COG1131	(ABC) transporter
BC_4081	COG1846	Transcriptional regulator
BC_4084	COG0598	Magnesium transport protein CorA
BC_4089	COG4974	Belongs to the 'phage' integrase family
BC_4091	COG0735	belongs to the Fur family
BC_4092	COG1300	Membrane
BC_4096	COG0667	Aldo Keto reductase
BC_4097	COG0656	L-ascorbic acid biosynthetic process
BC_4098	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC_4098	COG0456	acetyltransferase
BC_4100	COG4085	toxin activity
BC_4100	COG0737	Belongs to the 5'-nucleotidase family
BC_4100	COG1525	nuclease
BC_4102	COG0596	Alpha beta hydrolase
BC_4103	COG2056	Na+-H+ antiporter family
BC_4104	COG1609	Transcriptional regulator
BC_4105	COG0456	acetyltransferase
BC_4106	COG1073	alpha beta
BC_4109	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC_4109	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC_4110	COG0307	riboflavin synthase, alpha
BC_4116	COG2226	methyltransferase
BC_4116	COG1073	alpha beta
BC_4119	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC_4124	COG1522	sequence-specific DNA binding
BC_4133	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_4134	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC_4135	COG1760	l-serine dehydratase
BC_4136	COG1760	l-serine dehydratase
BC_4141	COG1285	pathogenesis
BC_4143	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC_4144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_4146	COG1376	ErfK ybiS ycfS ynhG family protein
BC_4147	COG4129	membrane
BC_4148	COG1126	abc transporter atp-binding protein
BC_4149	COG0765	amino acid transport
BC_4150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC_4153	COG2816	NAD+ diphosphatase activity
BC_4154	COG2323	membrane
BC_4155	COG0772	Belongs to the SEDS family
BC_4157	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC_4158	COG0022	dehydrogenase e1 component
BC_4159	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC_4160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC_4162	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC_4163	COG0280	phosphate acetyltransferase
BC_4165	COG3290	protein histidine kinase activity
BC_4165	COG3829	transcription factor binding
BC_4167	COG0584	glycerophosphoryl diester phosphodiesterase
BC_4168	COG3093	addiction module antidote protein HigA
BC_4172	COG0750	zinc metalloprotease
BC_4175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BC_4177	COG0142	geranyltranstransferase activity
BC_4182	COG1302	Protein conserved in bacteria
BC_4183	COG0439	Biotin carboxylase
BC_4184	COG0511	ligase activity, forming carbon-carbon bonds
BC_4193	COG3854	ATPases associated with a variety of cellular activities
BC_4198	COG0006	proline dipeptidase activity
BC_4201	COG3872	metal-dependent enzyme
BC_4203	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC_4210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_4211	COG1609	Transcriptional regulator
BC_4213	COG2076	Multidrug Resistance protein
BC_4214	COG2076	Multidrug Resistance protein
BC_4221	COG1131	(ABC) transporter
BC_4222	COG1725	Transcriptional regulator
BC_4227	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC_4238	COG1459	type II secretion system
BC_4239	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC_4250	COG0646	methionine synthase
BC_4250	COG1410	methionine synthase
BC_4251	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC_4251	COG0646	methionine synthase
BC_4253	COG0626	cystathionine gamma-synthase activity
BC_4254	COG0626	cystathionine gamma-synthase activity
BC_4258	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_4260	COG1940	carbohydrate kinase activity
BC_4261	COG4483	Protein conserved in bacteria
BC_4262	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC_4264	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC_4265	COG0704	Plays a role in the regulation of phosphate uptake
BC_4267	COG0573	inorganic phosphate transmembrane transporter activity
BC_4268	COG0573	inorganic phosphate transmembrane transporter activity
BC_4269	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC_4271	COG0477	Major facilitator Superfamily
BC_4274	COG5521	maltodextrose utilization protein MalA
BC_4277	COG0735	belongs to the Fur family
BC_4278	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC_4279	COG1121	(ABC) transporter
BC_4280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_4286	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC_4287	COG2384	SAM-dependent methyltransferase
BC_4289	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC_4290	COG0358	DNA primase activity
BC_4294	COG0517	IMP dehydrogenase activity
BC_4297	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC_4298	COG0295	cytidine deaminase activity
BC_4299	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BC_4301	COG1480	7TM receptor with intracellular HD hydrolase
BC_4302	COG1702	phosphate starvation-inducible protein PhoH
BC_4306	COG1610	YqeY-like protein
BC_4308	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC_4309	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC_4315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC_4316	COG1733	regulation of RNA biosynthetic process
BC_4321	COG1466	dna polymerase III delta subunit
BC_4322	COG2333	competence protein COMEC
BC_4322	COG0658	competence protein
BC_4323	COG2131	deaminase
BC_4324	COG1555	photosystem II stabilization
BC_4324	COG1596	polysaccharide export
BC_4325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC_4326	COG2226	methyltransferase
BC_4327	COG0799	negative regulation of ribosome biogenesis
BC_4328	COG1713	HD superfamily hydrolase involved in NAD metabolism
BC_4330	COG1534	Rna-binding protein
BC_4332	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BC_4333	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BC_4336	COG1191	sigma factor activity
BC_4340	COG0778	Nitroreductase
BC_4341	COG2357	RelA SpoT domain protein
BC_4343	COG1785	Belongs to the alkaline phosphatase family
BC_4345	COG2267	carboxylic ester hydrolase activity
BC_4351	COG1404	Belongs to the peptidase S8 family
BC_4352	COG3186	Phenylalanine-4-hydroxylase
BC_4354	COG2514	catechol 2,3-dioxygenase activity
BC_4355	COG2259	Doxx family
BC_4363	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BC_4365	COG1454	alcohol dehydrogenase
BC_4365	COG1012	belongs to the aldehyde dehydrogenase family
BC_4366	COG0626	cystathionine gamma-synthase activity
BC_4367	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC_4372	COG0768	penicillin binding
BC_4379	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC_4385	COG0628	permease
BC_4389	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC_4392	COG1104	cysteine desulfurase activity
BC_4393	COG1959	2 iron, 2 sulfur cluster binding
BC_4394	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC_4396	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC_4401	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC_4403	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BC_4403	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BC_4404	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC_4405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC_4405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC_4407	COG2244	polysaccharide biosynthetic process
BC_4408	COG2323	membrane
BC_4410	COG1862	Preprotein translocase
BC_4416	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BC_4422	COG0157	Belongs to the NadC ModD family
BC_4423	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC_4424	COG1104	cysteine desulfurase activity
BC_4425	COG1827	regulation of RNA biosynthetic process
BC_4426	COG2258	MOSC domain
BC_4427	COG0077	Prephenate dehydratase
BC_4428	COG0577	efflux transmembrane transporter activity
BC_4430	COG0577	efflux transmembrane transporter activity
BC_4431	COG1136	(ABC) transporter
BC_4432	COG5002	protein histidine kinase activity
BC_4433	COG0745	RESPONSE REGULATOR receiver
BC_4435	COG3290	protein histidine kinase activity
BC_4437	COG2868	ribosomal protein
BC_4439	COG1530	ribonuclease E activity
BC_4440	COG1994	Peptidase M50
BC_4441	COG0739	heme binding
BC_4442	COG2894	cell division
BC_4445	COG1792	Involved in formation and maintenance of cell shape
BC_4446	COG1077	Cell shape determining protein MreB Mrl
BC_4456	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC_4457	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC_4464	COG0285	dihydrofolate synthase activity
BC_4467	COG1388	LysM domain
BC_4469	COG0113	porphobilinogen synthase activity
BC_4470	COG1587	Uroporphyrinogen-III synthase
BC_4472	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC_4474	COG1846	Transcriptional regulator
BC_4475	COG1764	response to oxidative stress
BC_4478	COG1067	ATP-dependent peptidase activity
BC_4478	COG0470	DNA polymerase III
BC_4487	COG0210	DNA helicase
BC_4492	COG0622	Phosphoesterase
BC_4495	COG5401	PFAM Sporulation and spore germination
BC_4499	COG1309	transcriptional regulator
BC_4501	COG2197	response regulator
BC_4502	COG2233	PERMEase
BC_4503	COG0402	S-adenosylhomocysteine deaminase activity
BC_4504	COG1983	PspC domain protein
BC_4505	COG1396	sequence-specific DNA binding
BC_4508	COG1959	2 iron, 2 sulfur cluster binding
BC_4509	COG1668	transmembrane transport
BC_4510	COG4152	abc transporter atp-binding protein
BC_4511	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BC_4512	COG1360	Flagellar Motor Protein
BC_4513	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC_4514	COG1876	peptidase activity
BC_4515	COG0824	Thioesterase
BC_4516	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC_4517	COG1053	succinate dehydrogenase
BC_4518	COG2009	succinate dehydrogenase
BC_4519	COG1719	4-vinyl reductase, 4VR
BC_4521	COG3118	belongs to the thioredoxin family
BC_4523	COG2086	electron transfer activity
BC_4524	COG1024	Enoyl-CoA hydratase
BC_4525	COG1309	transcriptional regulator
BC_4526	COG0318	PFAM AMP-dependent synthetase and ligase
BC_4531	COG2318	DinB family
BC_4537	COG1131	(ABC) transporter
BC_4538	COG2205	protein histidine kinase activity
BC_4539	COG0745	RESPONSE REGULATOR receiver
BC_4540	COG4895	conserved protein (DUF2196)
BC_4541	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BC_4543	COG4509	Sortase family
BC_4544	COG1120	ATPase activity
BC_4547	COG5386	Cell surface protein
BC_4549	COG5386	Cell surface protein
BC_4550	COG1114	Component of the transport system for branched-chain amino acids
BC_4551	COG1187	pseudouridine synthase activity
BC_4553	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC_4553	COG1796	DNA polymerase
BC_4554	COG1286	toxin biosynthetic process
BC_4562	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC_4564	COG1418	mRNA catabolic process
BC_4568	COG2814	Major facilitator Superfamily
BC_4569	COG1566	PFAM secretion protein HlyD family protein
BC_4570	COG1309	transcriptional regulator
BC_4571	COG1363	Peptidase, m42
BC_4576	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC_4579	COG1484	DNA-dependent DNA replication
BC_4580	COG3611	Membrane attachment protein
BC_4582	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BC_4583	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC_4585	COG1971	Probably functions as a manganese efflux pump
BC_4587	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC_4587	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC_4588	COG5002	protein histidine kinase activity
BC_4589	COG0745	RESPONSE REGULATOR receiver
BC_4593	COG0538	isocitrate dehydrogenase activity
BC_4594	COG0372	Belongs to the citrate synthase family
BC_4597	COG0628	permease
BC_4598	COG3030	protein affecting phage T7 exclusion by the F plasmid
BC_4603	COG1725	Transcriptional regulator
BC_4604	COG0281	malic enzyme
BC_4605	COG0587	DNA-directed DNA polymerase activity
BC_4608	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC_4611	COG4109	DRTGG domain
BC_4614	COG0006	proline dipeptidase activity
BC_4620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_4621	COG0662	Cupin 2, conserved barrel domain protein
BC_4624	COG1028	Short-chain dehydrogenase reductase Sdr
BC_4625	COG0589	response to stress
BC_4633	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_4638	COG0827	DNA restriction-modification system
BC_4639	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC_4640	COG3874	Sporulation protein YtfJ
BC_4643	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BC_4645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC_4648	COG1104	cysteine desulfurase activity
BC_4650	COG0583	DNA-binding transcription factor activity
BC_4651	COG0697	spore germination
BC_4652	COG1309	transcriptional regulator
BC_4653	COG1956	GAF domain-containing protein
BC_4654	COG0626	cystathionine gamma-synthase activity
BC_4658	COG0110	maltose O-acetyltransferase activity
BC_4659	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC_4660	COG0454	-acetyltransferase
BC_4661	COG0517	IMP dehydrogenase activity
BC_4662	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC_4665	COG0745	RESPONSE REGULATOR receiver
BC_4667	COG0666	response to abiotic stimulus
BC_4672	COG1609	Transcriptional regulator
BC_4674	COG1605	Chorismate mutase
BC_4674	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC_4675	COG4851	CamS sex pheromone cAM373 precursor
BC_4676	COG3118	belongs to the thioredoxin family
BC_4678	COG2309	aminopeptidase activity
BC_4683	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_4686	COG1674	ftsk spoiiie
BC_4687	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC_4687	COG1388	LysM domain
BC_4689	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC_4691	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC_4692	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BC_4693	COG1363	Peptidase, m42
BC_4695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_4698	COG0510	thiamine kinase activity
BC_4702	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC_4703	COG1349	DNA-binding transcription factor activity
BC_4704	COG1187	pseudouridine synthase activity
BC_4705	COG2244	polysaccharide biosynthetic process
BC_4706	COG2081	HI0933 family
BC_4707	COG2814	Major facilitator Superfamily
BC_4709	COG3832	glyoxalase III activity
BC_4714	COG1329	Transcriptional regulator
BC_4719	COG0314	molybdopterin synthase activity
BC_4720	COG1763	Mo-molybdopterin cofactor biosynthetic process
BC_4721	COG0303	'Molybdopterin
BC_4723	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC_4724	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC_4728	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC_4730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC_4738	COG2814	Major facilitator Superfamily
BC_4739	COG0475	glutathione-regulated potassium exporter activity
BC_4740	COG0490	domain, Protein
BC_4741	COG0582	viral genome integration into host DNA
BC_4743	COG1136	(ABC) transporter
BC_4746	COG1242	4 iron, 4 sulfur cluster binding
BC_4747	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BC_4750	COG1794	racemase activity, acting on amino acids and derivatives
BC_4753	COG2267	carboxylic ester hydrolase activity
BC_4754	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BC_4755	COG0671	phosphoesterase, PA-phosphatase related
BC_4756	COG0438	transferase activity, transferring glycosyl groups
BC_4760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_4770	COG5002	protein histidine kinase activity
BC_4771	COG3852	Histidine kinase
BC_4774	COG2267	carboxylic ester hydrolase activity
BC_4775	COG1368	sulfuric ester hydrolase activity
BC_4778	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC_4779	COG1116	anion transmembrane transporter activity
BC_4780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC_4785	COG0494	nUDIX hydrolase
BC_4791	COG0288	reversible hydration of carbon dioxide
BC_4792	COG1271	oxidase subunit
BC_4793	COG1294	oxidase, subunit
BC_4796	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_4801	COG1842	Phage shock protein A
BC_4803	COG2801	Transposase and inactivated derivatives
BC_4809	COG5002	protein histidine kinase activity
BC_4810	COG0745	RESPONSE REGULATOR receiver
BC_4816	COG1597	lipid kinase activity
BC_4823	COG0577	efflux transmembrane transporter activity
BC_4824	COG1136	(ABC) transporter
BC_4825	COG1136	(ABC) transporter
BC_4828	COG0586	Pfam SNARE associated Golgi protein
BC_4829	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC_4830	COG0577	efflux transmembrane transporter activity
BC_4831	COG1136	(ABC) transporter
BC_4832	COG2207	Transcriptional regulator
BC_4832	COG3708	Transcriptional regulator
BC_4833	COG5658	integral membrane protein
BC_4834	COG0640	Transcriptional regulator
BC_4835	COG0745	RESPONSE REGULATOR receiver
BC_4836	COG2205	protein histidine kinase activity
BC_4837	COG0577	efflux transmembrane transporter activity
BC_4838	COG0577	efflux transmembrane transporter activity
BC_4839	COG1136	(ABC) transporter
BC_4840	COG0577	efflux transmembrane transporter activity
BC_4846	COG3964	amidohydrolase
BC_4853	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC_4854	COG0596	Alpha beta hydrolase
BC_4856	COG1169	isochorismate synthase
BC_4857	COG1575	Belongs to the MenA family. Type 1 subfamily
BC_4858	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC_4859	COG1278	Cold shock
BC_4863	COG0058	SHG alpha-glucan phosphorylase activity
BC_4869	COG1404	Belongs to the peptidase S8 family
BC_4889	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC_4895	COG1285	pathogenesis
BC_4899	COG2155	Conserved Protein
BC_4900	COG1098	S1 RNA binding domain
BC_4901	COG0436	Aminotransferase
BC_4902	COG1522	sequence-specific DNA binding
BC_4903	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC_4904	COG2267	carboxylic ester hydrolase activity
BC_4906	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC_4910	COG5018	Exonuclease
BC_4911	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC_4915	COG2050	protein possibly involved in aromatic compounds catabolism
BC_4917	COG1268	BioY protein
BC_4918	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC_4919	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC_4922	COG3584	3D domain protein
BC_4925	COG1252	NADH dehydrogenase
BC_4928	COG3708	Transcriptional regulator
BC_4931	COG1683	Conserved Protein
BC_4935	COG0316	Belongs to the HesB IscA family
BC_4938	COG1252	NADH dehydrogenase
BC_4941	COG0390	transport system, permease component
BC_4942	COG2824	Alkylphosphonate utilization operon protein PhnA
BC_4951	COG4837	Protein of unknown function (DUF1462)
BC_4952	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BC_4954	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC_4955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC_4958	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC_4959	COG0647	UMP catabolic process
BC_4961	COG2445	Protein of unknown function DUF86
BC_4962	COG1494	fructose-1,6-bisphosphatase
BC_4966	COG4470	Protein conserved in bacteria
BC_4968	COG0789	Transcriptional regulator
BC_4969	COG4377	Putative membrane peptidase family (DUF2324)
BC_4974	COG0739	heme binding
BC_4976	COG3377	Domain of unknown function (DUF1805)
BC_4977	COG0737	Belongs to the 5'-nucleotidase family
BC_4979	COG0719	Fe-S assembly protein
BC_4980	COG0822	iron-sulfur transferase activity
BC_4981	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC_4982	COG0719	Fe-S assembly protein
BC_4983	COG0396	ATPase activity
BC_4984	COG1464	Belongs to the NlpA lipoprotein family
BC_4985	COG1464	Belongs to the NlpA lipoprotein family
BC_4986	COG2011	ABC-type metal ion transport system permease component
BC_4989	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC_4990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BC_4992	COG1393	Belongs to the ArsC family
BC_5000	COG1309	transcriptional regulator
BC_5001	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC_5002	COG1960	acyl-CoA dehydrogenase activity
BC_5003	COG0183	Belongs to the thiolase family
BC_5004	COG1024	Enoyl-CoA hydratase
BC_5004	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC_5005	COG1686	Belongs to the peptidase S11 family
BC_5008	COG0011	TIGRFAM Protein of
BC_5009	COG0840	transmembrane signaling receptor activity
BC_5012	COG2814	Major facilitator Superfamily
BC_5013	COG0531	amino acid
BC_5018	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC_5025	COG0586	Pfam SNARE associated Golgi protein
BC_5027	COG1376	ErfK ybiS ycfS ynhG family protein
BC_5028	COG0745	RESPONSE REGULATOR receiver
BC_5029	COG5002	protein histidine kinase activity
BC_5034	COG0840	transmembrane signaling receptor activity
BC_5035	COG2151	metal-sulfur cluster biosynthetic enzyme
BC_5036	COG3227	Zinc metalloprotease (Elastase)
BC_5037	COG1741	Belongs to the pirin family
BC_5040	COG0586	Pfam SNARE associated Golgi protein
BC_5041	COG0475	glutathione-regulated potassium exporter activity
BC_5042	COG0490	domain, Protein
BC_5043	COG1115	amino acid carrier protein
BC_5044	COG0783	Belongs to the Dps family
BC_5046	COG1611	Belongs to the LOG family
BC_5048	COG1528	Iron-storage protein
BC_5050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_5051	COG1115	amino acid carrier protein
BC_5054	COG2910	NAD(P)H-binding
BC_5057	COG0656	L-ascorbic acid biosynthetic process
BC_5058	COG2814	Major facilitator Superfamily
BC_5059	COG1733	regulation of RNA biosynthetic process
BC_5061	COG1252	NADH dehydrogenase
BC_5065	COG0840	transmembrane signaling receptor activity
BC_5065	COG3290	protein histidine kinase activity
BC_5072	COG0488	(ABC) transporter
BC_5073	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC_5076	COG4221	oxidoreductase activity
BC_5079	COG1028	Short-chain dehydrogenase reductase Sdr
BC_5097	COG1522	sequence-specific DNA binding
BC_5126	COG3316	Transposase and inactivated derivatives
BC_5129	COG0557	exoribonuclease II activity
BC_5130	COG1647	Serine aminopeptidase, S33
BC_5131	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC_5132	COG1346	cytolysis
BC_5140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC_5143	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC_5148	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC_5151	COG2323	membrane
BC_5153	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC_5155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC_5157	COG1051	belongs to the nudix hydrolase family
BC_5159	COG0492	ferredoxin-NADP+ reductase activity
BC_5160	COG0457	Tetratricopeptide repeat
BC_5161	COG0110	maltose O-acetyltransferase activity
BC_5165	COG1950	PFAM Membrane protein of
BC_5167	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC_5171	COG0789	Transcriptional regulator
BC_5175	COG0583	DNA-binding transcription factor activity
BC_5177	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC_5179	COG2963	transposase activity
BC_5180	COG2801	Transposase and inactivated derivatives
BC_5182	COG1132	(ABC) transporter
BC_5183	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC_5184	COG0793	Belongs to the peptidase S41A family
BC_5184	COG3409	Peptidoglycan-binding domain 1 protein
BC_5185	COG2177	Part of the ABC transporter FtsEX involved in
BC_5186	COG2884	Cell division ATP-binding protein ftsE
BC_5188	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC_5190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC_5191	COG1278	Cold shock
BC_5192	COG1040	competence protein
BC_5193	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BC_5196	COG1388	LysM domain
BC_5196	COG0791	NLP P60 protein
BC_5197	COG1733	regulation of RNA biosynthetic process
BC_5198	COG1307	EDD domain protein, DegV family
BC_5199	COG1739	Uncharacterized protein family UPF0029
BC_5200	COG1316	TRANSCRIPTIONal
BC_5201	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BC_5202	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC_5203	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC_5205	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BC_5205	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BC_5209	COG1486	melibiose metabolic process
BC_5210	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC_5211	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC_5215	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC_5217	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC_5218	COG1301	dicarboxylic acid transport
BC_5221	COG1511	domain protein
BC_5222	COG0583	DNA-binding transcription factor activity
BC_5223	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BC_5224	COG1271	oxidase subunit
BC_5225	COG1294	oxidase, subunit
BC_5226	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC_5228	COG1620	l-lactate permease
BC_5230	COG2389	metal-binding protein
BC_5232	COG1368	sulfuric ester hydrolase activity
BC_5234	COG0791	NLP P60 protein
BC_5234	COG1388	LysM domain
BC_5235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC_5237	COG1215	transferase activity, transferring glycosyl groups
BC_5238	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC_5239	COG1388	LysM domain
BC_5239	COG3584	3D domain protein
BC_5244	COG4715	Zinc finger, swim domain protein
BC_5245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC_5251	COG1191	sigma factor activity
BC_5253	COG0577	efflux transmembrane transporter activity
BC_5254	COG1136	(ABC) transporter
BC_5261	COG5002	protein histidine kinase activity
BC_5262	COG0745	RESPONSE REGULATOR receiver
BC_5263	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC_5267	COG1442	glycosyl transferase family 8
BC_5267	COG1216	Glycosyl transferase, family 2
BC_5270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC_5272	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC_5273	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC_5274	COG1086	Polysaccharide biosynthesis protein
BC_5275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC_5276	COG4464	protein tyrosine phosphatase activity
BC_5277	COG0489	protein tyrosine kinase activity
BC_5278	COG3944	biosynthesis protein
BC_5279	COG0489	protein tyrosine kinase activity
BC_5282	COG1609	Transcriptional regulator
BC_5283	COG0739	heme binding
BC_5286	COG3279	Response regulator of the LytR AlgR family
BC_5287	COG2385	sporulation resulting in formation of a cellular spore
BC_5290	COG4836	Membrane
BC_5291	COG1007	ATP synthesis coupled electron transport
BC_5292	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC_5293	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC_5295	COG0839	Belongs to the complex I subunit 6 family
BC_5299	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC_5302	COG3300	MHYT domain
BC_5302	COG5001	Diguanylate cyclase
BC_5312	COG0356	it plays a direct role in the translocation of protons across the membrane
BC_5318	COG0698	ribose 5-phosphate isomerase
BC_5321	COG2259	Doxx family
BC_5322	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC_5325	COG0009	L-threonylcarbamoyladenylate synthase
BC_5332	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC_5333	COG1494	fructose-1,6-bisphosphatase
BC_5337	COG4821	SIS domain
BC_5341	COG1960	acyl-CoA dehydrogenase activity
BC_5342	COG1960	acyl-CoA dehydrogenase activity
BC_5343	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC_5344	COG0183	Belongs to the thiolase family
BC_5345	COG2181	nitrate reductase activity
BC_5345	COG0247	lactate metabolic process
BC_5346	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC_5351	COG3227	Zinc metalloprotease (Elastase)
BC_5352	COG2197	response regulator
BC_5353	COG4585	Histidine kinase
BC_5354	COG0842	Transport permease protein
BC_5355	COG1131	(ABC) transporter
BC_5356	COG0024	Methionine aminopeptidase
BC_5359	COG2234	aminopeptidase activity
BC_5363	COG1595	DNA-templated transcription, initiation
BC_5365	COG4506	Protein conserved in bacteria
BC_5366	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC_5372	COG2814	Major facilitator Superfamily
BC_5373	COG0789	Transcriptional regulator
BC_5374	COG0584	glycerophosphoryl diester phosphodiesterase
BC_5375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC_5377	COG1994	Peptidase M50
BC_5379	COG1078	dGTPase activity
BC_5380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC_5381	COG1120	ATPase activity
BC_5382	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_5383	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC_5387	COG0280	phosphate acetyltransferase
BC_5390	COG3773	Cell wall hydrolase
BC_5392	COG2363	Small membrane protein
BC_5394	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC_5395	COG2233	PERMEase
BC_5396	COG0561	phosphatase activity
BC_5397	COG2814	Major facilitator Superfamily
BC_5399	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BC_5400	COG1131	(ABC) transporter
BC_5401	COG2755	lipolytic protein G-D-S-L family
BC_5402	COG1609	Transcriptional regulator
BC_5404	COG0460	homoserine dehydrogenase
BC_5408	COG1011	Hydrolase
BC_5409	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC_5411	COG2197	response regulator
BC_5412	COG4585	Histidine kinase
BC_5412	COG2203	Gaf domain
BC_5413	COG0351	phosphomethylpyrimidine kinase
BC_5414	COG3706	GGDEF domain
BC_5415	COG2879	small protein
BC_5416	COG1966	Carbon starvation protein
BC_5417	COG3279	Response regulator of the LytR AlgR family
BC_5418	COG0477	Major facilitator Superfamily
BC_5420	COG0438	transferase activity, transferring glycosyl groups
BC_5424	COG0840	transmembrane signaling receptor activity
BC_5426	COG1607	acyl-coa hydrolase
BC_5427	COG1216	Glycosyl transferase, family 2
BC_5429	COG1216	Glycosyl transferase, family 2
BC_5432	COG0463	Glycosyl transferase, family 2
BC_5433	COG0488	(ABC) transporter
BC_5434	COG1309	transcriptional regulator
BC_5435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC_5436	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC_5436	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC_5437	COG0628	permease
BC_5442	COG2814	Major facilitator Superfamily
BC_5443	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC_5444	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BC_5448	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC_5449	COG1272	protein, Hemolysin III
BC_5453	COG1164	Oligoendopeptidase f
BC_5455	COG5002	protein histidine kinase activity
BC_5458	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC_5460	COG4853	Protein conserved in bacteria
BC_5462	COG5002	protein histidine kinase activity
BC_5463	COG0745	RESPONSE REGULATOR receiver
BC_5472	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BC_5473	COG4241	membrane
BC_5477	COG0012	GTP binding
BC_5478	COG4481	Protein conserved in bacteria
BC_5479	COG0668	transmembrane transport
BC_5481	COG1475	DNA binding
BC_5482	COG1192	Involved in chromosome partitioning
BC_5487	COG1847	R3H domain protein
BC_p0006	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair