locus-tag class description BCB4264_A0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCB4264_A0003 ENOG410848D S4 domain protein YaaA BCB4264_A0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCB4264_A0012 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCB4264_A0019 ENOG4105ZMH deoxynucleoside kinase BCB4264_A0021 ENOG4105GTG Isochorismatase BCB4264_A0022 ENOG4108Z6B deaminase BCB4264_A0024 ENOG4105C6E dna polymerase iii BCB4264_A0028 ENOG41067KS pro-sigma K processing BCB4264_A0034 ENOG4105CXN decarboxylase BCB4264_A0036 ENOG4105FA2 dna polymerase iii BCB4264_A0037 ENOG4105MA4 psp1 domain protein BCB4264_A0039 ENOG41060K3 Methyltransferase BCB4264_A0041 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCB4264_A0042 ENOG4105KRN Transcriptional regulator, abrb family BCB4264_A0043 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BCB4264_A0044 ENOG4105F8V Hydrolase, tatD family BCB4264_A0045 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCB4264_A0047 ENOG4105XFA sporulation peptidase YabG BCB4264_A0048 ENOG4105W42 Veg protein BCB4264_A0051 ENOG4105DFT pur operon repressor BCB4264_A0052 ENOG4105KME endoribonuclease L-psp BCB4264_A0055 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCB4264_A0056 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BCB4264_A0058 ENOG4108JA2 transcriptioN-repair coupling factor BCB4264_A0059 ENOG4108M14 stage v sporulation protein t BCB4264_A0061 ENOG4108IY2 MazG family BCB4264_A0062 ENOG41082I2 s4 domain protein BCB4264_A0063 ENOG4105VYY sporulation protein yabp BCB4264_A0066 ENOG41060GV RNA binding s1 domain protein BCB4264_A0070 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BCB4264_A0071 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCB4264_A0072 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCB4264_A0075 ENOG4105C6T cysteine synthase BCB4264_A0076 ENOG4105CRQ synthase (Component I) BCB4264_A0077 ENOG4105DDQ anthranilate synthase BCB4264_A0078 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCB4264_A0079 ENOG4105EEI dihydropteroate synthase BCB4264_A0080 ENOG4105KRF dihydroneopterin aldolase BCB4264_A0081 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCB4264_A0083 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCB4264_A0100 ENOG4108Z0C Uvrb UvrC protein BCB4264_A0103 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCB4264_A0105 ENOG4105CTP PilT protein domain protein BCB4264_A0106 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BCB4264_A0109 ENOG4105D7W serine acetyltransferase BCB4264_A0112 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCB4264_A0113 ENOG4105M0M Tetracycline resistance protein BCB4264_A0114 ENOG4105QIV RNA polymerase BCB4264_A0116 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCB4264_A0122 ENOG4107Y49 methyltransferase BCB4264_A0125 ENOG4105XPM ribosomal protein BCB4264_A0146 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCB4264_A0151 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCB4264_A0153 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCB4264_A0155 ENOG41067V7 50S ribosomal protein L36 BCB4264_A0160 ENOG4108JJB ABC transporter BCB4264_A0161 ENOG4108JJB ABC transporter BCB4264_A0162 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCB4264_A0163 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BCB4264_A0169 ENOG4105D1F ATP-binding protein BCB4264_A0172 ENOG4108NMV polysaccharide deacetylase BCB4264_A0187 ENOG4105C8B TIGR00159 family BCB4264_A0188 ENOG4107U5W ybbr family BCB4264_A0191 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BCB4264_A0196 ENOG4108PSK reductase BCB4264_A0197 ENOG4108UMI ABC transporter, permease BCB4264_A0198 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A0199 ENOG4105D01 (LipO)protein BCB4264_A0201 ENOG4105CB2 alcohol dehydrogenase BCB4264_A0203 ENOG4105IQ5 FAD linked oxidase domain protein BCB4264_A0206 ENOG4105C2C drug resistance transporter, Bcr CflA BCB4264_A0210 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCB4264_A0211 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCB4264_A0212 ENOG4105C3U ABC transporter BCB4264_A0213 ENOG4108JQ7 (ABC) transporter BCB4264_A0219 ENOG4108J59 Extracellular solute-binding protein, family 5 BCB4264_A0220 ENOG4108J59 Extracellular solute-binding protein, family 5 BCB4264_A0227 ENOG4105E0C molybdate abc transporter BCB4264_A0228 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCB4264_A0229 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCB4264_A0230 ENOG4105EGI Transcriptional regulator BCB4264_A0233 ENOG4105F6E Acyl-transferase BCB4264_A0235 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCB4264_A0239 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCB4264_A0243 ENOG4105C5H ABC transporter BCB4264_A0245 ENOG4105DEF Extracellular solute-binding protein, family 5 BCB4264_A0247 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCB4264_A0248 ENOG4105C3U ABC transporter BCB4264_A0249 ENOG4108JQ7 (ABC) transporter BCB4264_A0250 ENOG410667J hydrolase BCB4264_A0255 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCB4264_A0256 ENOG4105ERH Fumarylacetoacetate hydrolase BCB4264_A0258 ENOG4105CUB amino acid BCB4264_A0259 ENOG4108SC4 )-transporter BCB4264_A0260 ENOG4105CPF Cell wall formation (By similarity) BCB4264_A0261 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCB4264_A0266 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCB4264_A0267 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCB4264_A0269 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCB4264_A0289 ENOG4105K8N protein family UPF0079, ATPase BCB4264_A0290 ENOG41072GX Peptidase M22 Glycoprotease BCB4264_A0291 ENOG410801F ribosomal-protein-alanine acetyltransferase BCB4264_A0292 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCB4264_A0293 ENOG4105C5H ABC transporter BCB4264_A0296 ENOG4108TYN CAAX amino terminal protease family protein BCB4264_A0302 ENOG4105C7N Xanthine uracil vitamin C permease BCB4264_A0304 ENOG4105BZU Histidine kinase BCB4264_A0308 ENOG4107ZXU DSBA oxidoreductase BCB4264_A0315 ENOG4105BZU Histidine kinase BCB4264_A0316 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A0323 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BCB4264_A0328 ENOG4105SX7 Transporter BCB4264_A0334 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCB4264_A0335 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCB4264_A0336 ENOG4105C83 adenylosuccinate lyase BCB4264_A0338 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCB4264_A0343 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCB4264_A0345 ENOG4105C12 Phosphoribosylglycinamide synthetase BCB4264_A0351 ENOG4105C4R Atp-dependent dna helicase BCB4264_A0356 ENOG4108W2Y isochorismatase BCB4264_A0358 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A0359 ENOG4108UMI ABC transporter, permease BCB4264_A0360 ENOG4105D01 (LipO)protein BCB4264_A0364 ENOG410834F Transcriptional regulator BCB4264_A0369 ENOG4105CBD Diacylglycerol kinase BCB4264_A0371 ENOG4108JPW Aminotransferase BCB4264_A0373 ENOG4105C26 Dehydrogenase BCB4264_A0374 ENOG4105KPY Small multidrug resistance protein BCB4264_A0379 ENOG4105D9N nucleoside BCB4264_A0381 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCB4264_A0383 ENOG4108W15 Protein of unknown function (DUF1456) BCB4264_A0386 ENOG4105DTQ mandelate racemase muconate lactonizing BCB4264_A0388 ENOG4105DFD Na H antiporter BCB4264_A0392 ENOG4105D3R alkyl hydroperoxide reductase BCB4264_A0393 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BCB4264_A0394 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BCB4264_A0395 ENOG4107W7X Aldolase BCB4264_A0396 ENOG4105EHG Permease protein BCB4264_A0397 ENOG4105DQ5 transport system permease protein BCB4264_A0398 ENOG4108V5C ABC transporter BCB4264_A0399 ENOG4105CAY ferredoxin--nadp reductase BCB4264_A0403 ENOG4106UIA BCB4264_A0406 ENOG4105BZU Histidine kinase BCB4264_A0411 ENOG410756H nucleotidyltransferase BCB4264_A0412 ENOG4105D2S major facilitator superfamily BCB4264_A0415 ENOG4105E5Q amino acid AbC transporter BCB4264_A0416 ENOG4105EAB amino acid AbC transporter BCB4264_A0418 ENOG4105C8Q Methyl-accepting chemotaxis BCB4264_A0421 ENOG4105DBV ornithine carbamoyltransferase BCB4264_A0423 ENOG4105C5B carbamate kinase BCB4264_A0424 ENOG4108W63 CRP FNR family transcriptional regulator BCB4264_A0426 ENOG4105DNP FAD linked oxidase domain protein BCB4264_A0428 ENOG4105CI1 PTS System BCB4264_A0441 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCB4264_A0446 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component BCB4264_A0447 ENOG4105D2X ABC transporter substrate-binding protein BCB4264_A0449 ENOG4105C5H ABC transporter BCB4264_A0455 ENOG41062JF Transcriptional regulator BCB4264_A0458 ENOG4105DEU major facilitator superfamily BCB4264_A0461 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BCB4264_A0464 ENOG4108N0M stress protein BCB4264_A0465 ENOG4106FN3 tellurium resistance protein BCB4264_A0466 ENOG4106FN3 tellurium resistance protein BCB4264_A0467 ENOG4107TS3 membrane protein, TerC BCB4264_A0468 ENOG4108TTB tellurium resistance protein BCB4264_A0471 ENOG41068PA UPF0435 protein BCB4264_A0472 ENOG4105KJF protein tyrosine phosphatase BCB4264_A0474 ENOG4107U9T Pfam:Ribonuclease_BN BCB4264_A0475 ENOG4105C59 p-type ATPase BCB4264_A0476 ENOG4108IPJ Membrane BCB4264_A0478 ENOG4105C3F Signal peptidase i BCB4264_A0480 ENOG4107ZTW SNARE associated Golgi BCB4264_A0483 ENOG410606W general stress protein BCB4264_A0484 ENOG4105UPD Calcium Proton BCB4264_A0491 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCB4264_A0492 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BCB4264_A0494 ENOG4108JUB Transcriptional regulator BCB4264_A0496 ENOG4108IQI permease BCB4264_A0505 ENOG4108A04 Beta-lactamase BCB4264_A0508 ENOG4105CKK Glycosyl transferase, family 2 BCB4264_A0509 ENOG4107QQG Dehydrogenase BCB4264_A0510 ENOG4105C3I Nad-dependent epimerase dehydratase BCB4264_A0513 ENOG4105F1A Pyruvate formate-lyase BCB4264_A0517 ENOG4105CI2 imidazolone-5-propionate hydrolase BCB4264_A0518 ENOG4105ECP epimerase BCB4264_A0524 ENOG41067AE Membrane-bound metal-dependent hydrolase BCB4264_A0525 ENOG4105CEN a g-specific adenine glycosylase BCB4264_A0526 ENOG4106BXE BCB4264_A0532 ENOG4105BZ1 (ABC) transporter BCB4264_A0533 ENOG4107NBY Membrane BCB4264_A0535 ENOG4105CBC glutamate synthase BCB4264_A0537 ENOG4108IUW ABC transporter BCB4264_A0541 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCB4264_A0542 ENOG4105G5W regulator Fur family BCB4264_A0562 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCB4264_A0577 ENOG4105CDY transcriptional regulatory protein BCB4264_A0579 ENOG4108JQC penicillin-binding protein 1A BCB4264_A0580 ENOG4108R9S DSBA oxidoreductase BCB4264_A0582 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCB4264_A0584 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCB4264_A0585 ENOG4105BZU Histidine kinase BCB4264_A0586 ENOG4105CYN Serine protein kinase BCB4264_A0590 ENOG4105C94 Transporter BCB4264_A0593 ENOG4105DZ6 Band 7 protein BCB4264_A0595 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCB4264_A0596 ENOG4108V9W transcriptional regulatory protein BCB4264_A0597 ENOG4105D4T Citrate transporter BCB4264_A0602 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCB4264_A0603 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A0604 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCB4264_A0605 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCB4264_A0606 ENOG4105BZ7 extracellular solute-binding protein family 1 BCB4264_A0607 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCB4264_A0608 ENOG4108STX response regulator BCB4264_A0609 ENOG41062D9 Histidine kinase BCB4264_A0615 ENOG4108MRH transcriptional regulatory protein BCB4264_A0617 ENOG4105C6K Malic enzyme BCB4264_A0619 ENOG4108UZ3 Transporter BCB4264_A0620 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A0622 ENOG4105BZU Histidine kinase BCB4264_A0626 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCB4264_A0627 ENOG4108JB9 formate dehydrogenase BCB4264_A0631 ENOG4105CUB amino acid BCB4264_A0634 ENOG4105C59 p-type ATPase BCB4264_A0635 ENOG4105DAP Nicotinate phosphoribosyltransferase BCB4264_A0642 ENOG41073R8 VanW family BCB4264_A0643 ENOG4108KGH TRANSCRIPTIONal BCB4264_A0644 ENOG4105D9N nucleoside BCB4264_A0645 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCB4264_A0646 ENOG4105C37 (CBS) domain BCB4264_A0647 ENOG4108IJ0 Aspartate ammonia-lyase BCB4264_A0648 ENOG4105DAA L-lactate BCB4264_A0651 ENOG4105DUX Transporter BCB4264_A0652 ENOG4108MES Periplasmic binding protein BCB4264_A0653 ENOG4105DQ5 transport system permease protein BCB4264_A0654 ENOG4108IHU transport system permease protein BCB4264_A0655 ENOG4105E0A ABC, transporter BCB4264_A0656 ENOG4105DMQ Methyltransferase BCB4264_A0657 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BCB4264_A0658 ENOG4105EXW epimerase dehydratase BCB4264_A0660 ENOG4107T89 von Willebrand factor, type A BCB4264_A0661 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCB4264_A0662 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCB4264_A0664 ENOG4105BZU Histidine kinase BCB4264_A0665 ENOG4105D5Q Arginine ornithine antiporter BCB4264_A0666 ENOG4107414 GntR family transcriptional regulator BCB4264_A0667 ENOG4105C5Y PTS System BCB4264_A0668 ENOG4105CG3 alpha amylase, catalytic region BCB4264_A0671 ENOG4105E1K spore germination protein BCB4264_A0672 ENOG4105CRN Aminoglycoside phosphotransferase BCB4264_A0673 ENOG4105BZG amino acid carrier protein BCB4264_A0675 ENOG4105CDA abc transporter atp-binding protein BCB4264_A0676 ENOG4105CT1 (ABC) transporter BCB4264_A0677 ENOG4105EAD ABC transporter BCB4264_A0678 ENOG4105DRP amino acid AbC transporter BCB4264_A0679 ENOG4108IQI permease BCB4264_A0684 ENOG4105D29 Helix-turn-helix type 11 domain protein BCB4264_A0685 ENOG4105NAE bifunctional deaminase-reductase domain protein BCB4264_A0686 ENOG4105BZU Histidine kinase BCB4264_A0689 ENOG4105CHH sulfate transporter BCB4264_A0690 ENOG41068KF Universal stress protein BCB4264_A0692 ENOG4105CXY transporter BCB4264_A0694 ENOG41067TZ transcriptional regulator, MarR family BCB4264_A0695 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCB4264_A0696 ENOG4105ETE Transcriptional regulator (LacI family BCB4264_A0697 ENOG4108RVA ribokinase BCB4264_A0699 ENOG4105C2J ABC transporter BCB4264_A0700 ENOG4105CNN ABC, transporter BCB4264_A0701 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCB4264_A0702 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCB4264_A0708 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BCB4264_A0714 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BCB4264_A0715 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCB4264_A0716 ENOG41069ER domain protein BCB4264_A0717 ENOG4105VZ8 Transcriptional regulator BCB4264_A0718 ENOG4107D63 BCB4264_A0721 ENOG4105DUX Transporter BCB4264_A0725 ENOG4105C85 amino acid BCB4264_A0726 ENOG4105C7N Xanthine uracil vitamin C permease BCB4264_A0728 ENOG4105D7V transposase BCB4264_A0731 ENOG4105MA6 gCN5-related N-acetyltransferase BCB4264_A0736 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCB4264_A0737 ENOG4105E2S oxidase) subunit II BCB4264_A0741 ENOG4106CAD Protein of unknown function (DUF3311) BCB4264_A0742 ENOG4105E1V na solute symporter BCB4264_A0745 ENOG4108NHD germination protein BCB4264_A0748 ENOG4105CE1 Ferrous iron transport protein b BCB4264_A0749 ENOG4105CE1 Ferrous iron transport protein b BCB4264_A0750 ENOG4105CVA phosphate BCB4264_A0751 ENOG4105C8U phosphate abc transporter BCB4264_A0752 ENOG4105E2Z phosphate ABC transporter (Permease BCB4264_A0776 ENOG41080XQ Signal transduction protein with cbs domains BCB4264_A0782 ENOG4105ETU transcriptional activator (TenA BCB4264_A0784 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCB4264_A0786 ENOG4108VEU Thiamine monophosphate synthase BCB4264_A0787 ENOG41080HI glycine oxidase BCB4264_A0790 ENOG4105D06 uba thif-type nad fad binding protein BCB4264_A0791 ENOG4105DWF phosphomethylpyrimidine kinase BCB4264_A0802 ENOG4108INS Transcriptional regulator BCB4264_A0804 ENOG4105C7N Xanthine uracil vitamin C permease BCB4264_A0806 ENOG4108PXI ErfK YbiS YcfS YnhG BCB4264_A0810 ENOG4105C5Y PTS System BCB4264_A0813 ENOG4105K63 Thioredoxin BCB4264_A0817 ENOG4108B31 Spore germination protein BCB4264_A0821 ENOG4107Y03 Nitroreductase BCB4264_A0822 ENOG4105ED1 spovr family BCB4264_A0828 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BCB4264_A0829 ENOG4105XTG Pfam:DUF156 BCB4264_A0830 ENOG4105VFE sira family BCB4264_A0831 ENOG4107TPS domain protein BCB4264_A0832 ENOG4105VFE sira family BCB4264_A0833 ENOG4105VFE sira family BCB4264_A0835 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCB4264_A0836 ENOG41087NI Sulfite exporter TauE/SafE BCB4264_A0838 ENOG4108KGH TRANSCRIPTIONal BCB4264_A0843 ENOG4105EMD TRANSCRIPTIONal BCB4264_A0844 ENOG4105VCP PTS System BCB4264_A0845 ENOG4105VZJ PTS System BCB4264_A0849 ENOG41069ER domain protein BCB4264_A0850 ENOG4107RBB ABC transporter, permease BCB4264_A0851 ENOG4105C19 ABC transporter BCB4264_A0857 ENOG4105WEF catalase BCB4264_A0865 ENOG4107T5V SNARE associated Golgi BCB4264_A0872 ENOG4105CUB amino acid BCB4264_A0873 ENOG4107RWR Sodium hydrogen exchanger BCB4264_A0875 ENOG4106KNT transcriptional regulator BCB4264_A0883 ENOG4108YXU transcriptional regulator AsnC family BCB4264_A0885 ENOG4108IXY short-chain dehydrogenase reductase BCB4264_A0887 ENOG4105KPY Small multidrug resistance protein BCB4264_A0895 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCB4264_A0896 ENOG4105E5W Transporter BCB4264_A0898 ENOG4107RKG DJ-1/PfpI family BCB4264_A0899 ENOG4105CH6 catalase BCB4264_A0901 ENOG4105D5Q Arginine ornithine antiporter BCB4264_A0903 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BCB4264_A0905 ENOG4105C26 Dehydrogenase BCB4264_A0906 ENOG4105BZ1 (ABC) transporter BCB4264_A0907 ENOG4105BZ1 (ABC) transporter BCB4264_A0909 ENOG4105DRP amino acid AbC transporter BCB4264_A0910 ENOG4105CDA abc transporter atp-binding protein BCB4264_A0913 ENOG410839P BCB4264_A0921 ENOG4107FQX Alpha-acetolactate decarboxylase BCB4264_A0925 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCB4264_A0926 ENOG4105D4P Coproporphyrinogen iii oxidase BCB4264_A0930 ENOG4105CHH sulfate transporter BCB4264_A0935 ENOG4105CGU Enoyl-CoA hydratase BCB4264_A0939 ENOG4105DER m42 family BCB4264_A0943 ENOG4105CTU Proline racemase BCB4264_A0944 ENOG4105CIF Ornithine Cyclodeaminase BCB4264_A0947 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCB4264_A0949 ENOG4108JQ7 (ABC) transporter BCB4264_A0952 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCB4264_A0962 ENOG4108IBT Inherit from COG: transposase BCB4264_A0964 ENOG4105CSH Transporter BCB4264_A0966 ENOG4108MRH transcriptional regulatory protein BCB4264_A0972 ENOG4107QMH DNA methylase BCB4264_A0983 ENOG4105CDU Replicative dna helicase BCB4264_A0988 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCB4264_A0992 ENOG4105D9U N-acetyltransferase BCB4264_A0994 ENOG4105F6J Alpha beta hydrolase fold BCB4264_A1002 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCB4264_A1006 ENOG4105CMT Dihydroxyacetone kinase BCB4264_A1008 ENOG4105CMT Dihydroxyacetone kinase BCB4264_A1015 ENOG41069ER domain protein BCB4264_A1018 ENOG4105DQ6 Transposase BCB4264_A1031 ENOG4105WN5 stage II sporulation protein BCB4264_A1033 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A1035 ENOG4108MJI response regulator BCB4264_A1036 ENOG4105BZU Histidine kinase BCB4264_A1037 ENOG4105BZU Histidine kinase BCB4264_A1042 ENOG4105K8R UPF0145 protein BCB4264_A1046 ENOG4107QHE Choloylglycine hydrolase BCB4264_A1050 ENOG4107VRP DNA repair exonuclease BCB4264_A1051 ENOG4106D4I domain protein BCB4264_A1055 ENOG4107JM4 Tetratricopeptide repeat BCB4264_A1057 ENOG4108MUZ hydrolase BCB4264_A1062 ENOG4105F0F Oxalate decarboxylase BCB4264_A1063 ENOG41067QW Transcriptional regulator BCB4264_A1064 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCB4264_A1067 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCB4264_A1075 ENOG4105EEM helicase BCB4264_A1077 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCB4264_A1083 ENOG4105K59 histidine triad (HIT) protein BCB4264_A1090 ENOG410905X membrane-flanked domain protein BCB4264_A1091 ENOG4105CKV Membrane BCB4264_A1099 ENOG410905X membrane-flanked domain protein BCB4264_A1100 ENOG4105CKV Membrane BCB4264_A1101 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCB4264_A1102 ENOG4105BZ4 penicillin-binding protein BCB4264_A1104 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCB4264_A1105 ENOG4105C1Q protoporphyrinogen oxidase BCB4264_A1110 ENOG4105NA0 Transcriptional regulator BCB4264_A1113 ENOG4105ECB domain protein BCB4264_A1113 ENOG4105ECB domain protein BCB4264_A1119 ENOG4106AXD BCB4264_A1120 ENOG4108RQ5 Beta-lactamase domain-containing protein BCB4264_A1121 ENOG4105DF9 Lipoate-protein, ligase BCB4264_A1123 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A1125 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BCB4264_A1126 ENOG4108I5D sulfate abc transporter BCB4264_A1127 ENOG4105ECW sulfate abc transporter BCB4264_A1128 ENOG4108IJ6 ABC transporter BCB4264_A1130 ENOG4105CNA YD repeat protein BCB4264_A1132 ENOG4105CNA YD repeat protein BCB4264_A1163 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BCB4264_A1165 ENOG4105ENX hydrolase BCB4264_A1166 ENOG4107RN3 metallophosphoesterase BCB4264_A1167 ENOG4107TVP HD domain protein BCB4264_A1169 ENOG4108AEY RNA polymerase sigma factor BCB4264_A1170 ENOG41086D8 Transcriptional regulator BCB4264_A1173 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A1177 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCB4264_A1178 ENOG4105C8Q Methyl-accepting chemotaxis BCB4264_A1179 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BCB4264_A1181 ENOG4107QP3 malate synthase g BCB4264_A1185 ENOG4105VEQ Cold shock protein BCB4264_A1194 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BCB4264_A1202 ENOG4105ERH Fumarylacetoacetate hydrolase BCB4264_A1204 ENOG4105C8Y Acetylornithine aminotransferase BCB4264_A1205 ENOG4106BKT UPF0344 protein BCB4264_A1207 ENOG4105CAQ asparagine synthetase BCB4264_A1208 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCB4264_A1209 ENOG4105CH6 catalase BCB4264_A1210 ENOG4105BZU Histidine kinase BCB4264_A1213 ENOG4108VPT UPF0234 protein BCB4264_A1214 ENOG4105QNR S1 RNA binding domain protein BCB4264_A1215 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCB4264_A1217 ENOG4107AYK membrAne BCB4264_A1218 ENOG41073B9 BCB4264_A1220 ENOG4108KP7 hydrolase BCB4264_A1223 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BCB4264_A1228 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCB4264_A1229 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCB4264_A1232 ENOG4105C31 Tryptophanyl-tRNA synthetase BCB4264_A1235 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCB4264_A1236 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCB4264_A1238 ENOG4108JQ7 (ABC) transporter BCB4264_A1239 ENOG4105UQX Mate efflux family protein BCB4264_A1243 ENOG4108ZCF integral membrane protein BCB4264_A1245 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCB4264_A1247 ENOG4105DPN Oligoendopeptidase f BCB4264_A1250 ENOG4108Z18 K06886 hemoglobin BCB4264_A1251 ENOG4105MIX Adenylate cyclase BCB4264_A1252 ENOG4106EFP UPF0738 protein BCB4264_A1254 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BCB4264_A1255 ENOG4105EMS pseudouridine synthase BCB4264_A1259 ENOG4105K64 Glycosyl transferase, family 2 BCB4264_A1263 ENOG4107TVC Glycosyl transferase, family 2 BCB4264_A1267 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCB4264_A1268 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCB4264_A1270 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCB4264_A1280 ENOG4105DQ6 Transposase BCB4264_A1283 ENOG4108ZMI UPF0477 protein BCB4264_A1289 ENOG4105CK7 Sodium proline symporter BCB4264_A1291 ENOG4105CRQ synthase (Component I) BCB4264_A1292 ENOG4105DDQ anthranilate synthase BCB4264_A1313 ENOG4105C7S Dehydrogenase BCB4264_A1315 ENOG4105VZ8 Transcriptional regulator BCB4264_A1328 ENOG4105DZ1 carboxypeptidase BCB4264_A1329 ENOG4105VFR signal peptidase BCB4264_A1336 ENOG4105C26 Dehydrogenase BCB4264_A1337 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A1338 ENOG4105F38 ABC transporter, permease BCB4264_A1339 ENOG4105D38 putrescine abc transporter BCB4264_A1340 ENOG4107RUE extracellular solute-binding protein family 1 BCB4264_A1342 ENOG4105EYF MMPL domain protein BCB4264_A1344 ENOG4108YBP pseudouridine synthase BCB4264_A1346 ENOG4105K4I Scp-like extracellular BCB4264_A1347 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCB4264_A1348 ENOG4105CQB FAD linked oxidase domain protein BCB4264_A1351 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A1352 ENOG4105BZU Histidine kinase BCB4264_A1353 ENOG4105JXH GntR family transcriptional regulator BCB4264_A1357 ENOG4106A3R peptidase BCB4264_A1359 ENOG4108QTI )-transporter BCB4264_A1360 ENOG4107TS3 membrane protein, TerC BCB4264_A1362 ENOG4105CZN Potassium uptake protein BCB4264_A1363 ENOG410681C small acid-soluble spore protein BCB4264_A1364 ENOG4108Z7G MaoC domain protein dehydratase BCB4264_A1368 ENOG4105CHR reductase BCB4264_A1374 ENOG4105C4Y ABC transporter BCB4264_A1376 ENOG4107RCV ABC transporter, permease BCB4264_A1380 ENOG4105E98 transcriptional regulator DeoR family BCB4264_A1383 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCB4264_A1385 ENOG4105PXI polysaccharide deacetylase BCB4264_A1387 ENOG4105BZU Histidine kinase BCB4264_A1388 ENOG41090MY MarR family Transcriptional regulator BCB4264_A1390 ENOG4106DF1 BCB4264_A1392 ENOG4105BZU Histidine kinase BCB4264_A1395 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCB4264_A1396 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCB4264_A1404 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCB4264_A1405 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCB4264_A1406 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCB4264_A1407 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A1408 ENOG4105CZV ABC transporter BCB4264_A1410 ENOG4105CJ1 ABC, transporter BCB4264_A1418 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCB4264_A1419 ENOG4105EA8 2-Nitropropane dioxygenase BCB4264_A1421 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCB4264_A1423 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCB4264_A1428 ENOG4105NQC Flavodoxin BCB4264_A1436 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BCB4264_A1442 ENOG4105CZN Potassium uptake protein BCB4264_A1443 ENOG41063Y9 BCB4264_A1444 ENOG4105KBJ sporulation protein ytfj BCB4264_A1449 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCB4264_A1450 ENOG4105C7K acetolactate synthase BCB4264_A1451 ENOG4108ZP8 Acetolactate synthase small subunit BCB4264_A1452 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BCB4264_A1459 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BCB4264_A1466 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCB4264_A1469 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCB4264_A1470 ENOG4105E0M Sulfatase BCB4264_A1473 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCB4264_A1478 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCB4264_A1479 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCB4264_A1481 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCB4264_A1482 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCB4264_A1483 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCB4264_A1484 ENOG4105C8J )-transporter BCB4264_A1490 ENOG4105DFD Na H antiporter BCB4264_A1494 ENOG4105ENE Histidine kinase BCB4264_A1495 ENOG4105WH1 Two component transcriptional regulator luxr family BCB4264_A1499 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCB4264_A1504 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BCB4264_A1508 ENOG4105CJ3 phosphate transporter BCB4264_A1509 ENOG4107GRR phosphate transport regulator BCB4264_A1510 ENOG4105BZ4 penicillin-binding protein BCB4264_A1513 ENOG4105BZU Histidine kinase BCB4264_A1514 ENOG4105I3N Conserved Protein BCB4264_A1517 ENOG4105BZU Histidine kinase BCB4264_A1523 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCB4264_A1524 ENOG4105DZ1 carboxypeptidase BCB4264_A1525 ENOG4108JIC nucleoside recognition domain protein BCB4264_A1527 ENOG4105FE9 pseudouridine synthase BCB4264_A1528 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCB4264_A1529 ENOG4107TWT Cytochrome c biogenesis protein BCB4264_A1530 ENOG4105CRE cytochrome C BCB4264_A1531 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A1532 ENOG4105BZU Histidine kinase BCB4264_A1533 ENOG4108WBT adenosyltransferase BCB4264_A1537 ENOG4108SAX Membrane BCB4264_A1540 ENOG4105C9U ATP-dependent DNA helicase RecQ BCB4264_A1541 ENOG4105I7S Abortive infection protein BCB4264_A1543 ENOG4107RGJ metallophosphoesterase BCB4264_A1544 ENOG4108XDN Transcriptional regulator BCB4264_A1545 ENOG4108S6Z Negative regulator of genetic competence BCB4264_A1550 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCB4264_A1551 ENOG4107RB3 L-asparaginase BCB4264_A1557 ENOG4105S2F BCB4264_A1558 ENOG41065D1 BCB4264_A1565 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCB4264_A1568 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCB4264_A1570 ENOG4105EAH synthase BCB4264_A1571 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BCB4264_A1572 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BCB4264_A1575 ENOG41068YB TPR repeat-containing protein BCB4264_A1578 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCB4264_A1579 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCB4264_A1586 ENOG4108JYZ YitT family BCB4264_A1587 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCB4264_A1590 ENOG4105FJR Lmbe family BCB4264_A1591 ENOG4105CPK Glycosyl transferase (Group 1 BCB4264_A1598 ENOG4105DVT helicase BCB4264_A1599 ENOG4105YAC BCB4264_A1603 ENOG4105CSM endonuclease III BCB4264_A1605 ENOG4105BZ4 penicillin-binding protein BCB4264_A1617 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCB4264_A1619 ENOG4105DVT helicase BCB4264_A1620 ENOG4105CTD carboxy-peptidase BCB4264_A1623 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCB4264_A1627 ENOG4105C2W permease BCB4264_A1628 ENOG4105DHF Membrane BCB4264_A1630 ENOG410890F Dynamin family BCB4264_A1632 ENOG4108W0I acetyltransferase BCB4264_A1634 ENOG4105KHC sulfurtransferase BCB4264_A1639 ENOG4106032 Glutathionylspermidine synthase BCB4264_A1646 ENOG4105HTX biosynthesis protein BCB4264_A1652 ENOG4105CPK Glycosyl transferase (Group 1 BCB4264_A1655 ENOG4108SZE gCN5-related N-acetyltransferase BCB4264_A1659 ENOG41081VK Ribonuclease BCB4264_A1673 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCB4264_A1675 ENOG4107RWR Sodium hydrogen exchanger BCB4264_A1676 ENOG4105CN5 Metallo-Beta-Lactamase BCB4264_A1677 ENOG4108Z5V transcriptional regulator, merr family BCB4264_A1679 ENOG4105H67 Protein of unknown function (DUF421) BCB4264_A1680 ENOG41080C8 DUF218 domain BCB4264_A1691 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCB4264_A1693 ENOG4107R0U MotA TolQ exbB proton channel BCB4264_A1694 ENOG4105ER2 Ompa motb domain protein BCB4264_A1695 ENOG4107YTP response regulator receiver protein BCB4264_A1696 ENOG4105CBS Chea signal transduction histidine kinase BCB4264_A1697 ENOG4105DD5 Flagellar motor switch protein BCB4264_A1700 ENOG4105BZU Histidine kinase BCB4264_A1704 ENOG4105E1Q flagellar hook-associated protein BCB4264_A1705 ENOG4105DTJ flagellar hook-associated protein BCB4264_A1709 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCB4264_A1710 ENOG4108ZC9 flagellar basal-body rod protein flgc BCB4264_A1711 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCB4264_A1712 ENOG4107U2N Flagellar M-ring protein BCB4264_A1714 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCB4264_A1720 ENOG4105BZE flagellar hook protein, FlgE BCB4264_A1723 ENOG4107R88 Chemotaxis protein (CheV) BCB4264_A1725 ENOG4105I03 Flagellin BCB4264_A1726 ENOG4105I03 Flagellin BCB4264_A1727 ENOG4105E4C Lytic transglycosylase catalytic BCB4264_A1729 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCB4264_A1730 ENOG4105DD5 Flagellar motor switch protein BCB4264_A1732 ENOG4105CN7 Flagellar biosynthetic protein FliP BCB4264_A1733 ENOG4105VS8 Flagellar biosynthetic protein fliq BCB4264_A1735 ENOG4105D00 flagellar biosynthetic protein flhB BCB4264_A1736 ENOG4105D7B Flagellar biosynthesis protein flha BCB4264_A1737 ENOG4105FZW flagellar biosynthesis regulator FlhF BCB4264_A1738 ENOG4105KTQ flagellar basal-body rod protein BCB4264_A1739 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCB4264_A1746 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCB4264_A1751 ENOG4105DUM transcriptional regulator, lysR family BCB4264_A1754 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCB4264_A1761 ENOG4105CVJ phosphoglycerate mutase BCB4264_A1763 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BCB4264_A1767 ENOG4105CAQ asparagine synthetase BCB4264_A1771 ENOG4105PGM cation diffusion facilitator family transporter BCB4264_A1773 ENOG4105DRR Transcriptional regulator, GntR family BCB4264_A1774 ENOG4108UZ3 Transporter BCB4264_A1776 ENOG4105CKI cobalamin synthesis protein BCB4264_A1777 ENOG4108PJD permease BCB4264_A1780 ENOG4105DFD Na H antiporter BCB4264_A1781 ENOG4105VUF Transcriptional regulator BCB4264_A1783 ENOG4105C9Q fumarate hydratase class II BCB4264_A1787 ENOG4107QJQ Mate efflux family protein BCB4264_A1788 ENOG4105EC3 peptidase S51, dipeptidase E BCB4264_A1792 ENOG4107QIV Cytochrome c biogenesis protein BCB4264_A1793 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCB4264_A1797 ENOG4106BRA Membrane BCB4264_A1804 ENOG4105CJ1 ABC, transporter BCB4264_A1808 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCB4264_A1811 ENOG4108IJ0 Aspartate ammonia-lyase BCB4264_A1812 ENOG4105C6K Malic enzyme BCB4264_A1825 ENOG4105FVX BCB4264_A1826 ENOG4105E09 nadh pyrophosphatase BCB4264_A1829 ENOG4105CSR polyphosphate kinase 2 BCB4264_A1832 ENOG4105DXI Major Facilitator superfamily BCB4264_A1835 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCB4264_A1836 ENOG4105EU0 Major facilitator Superfamily BCB4264_A1837 ENOG4105C6T cysteine synthase BCB4264_A1841 ENOG4105C8J )-transporter BCB4264_A1843 ENOG4105X5K response regulator receiver protein BCB4264_A1844 ENOG4105H67 Protein of unknown function (DUF421) BCB4264_A1848 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCB4264_A1849 ENOG4105CHR reductase BCB4264_A1850 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCB4264_A1851 ENOG4105C7K acetolactate synthase BCB4264_A1853 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BCB4264_A1855 ENOG4105C7B Threonine dehydratase BCB4264_A1859 ENOG4105C6X Major Facilitator BCB4264_A1860 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCB4264_A1862 ENOG4105DY9 regulatoR BCB4264_A1863 ENOG4105CYC Transferase BCB4264_A1864 ENOG4105K5X acetyltransferase BCB4264_A1868 ENOG41068WN BCB4264_A1874 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCB4264_A1875 ENOG4105C72 UPF0176 protein BCB4264_A1877 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCB4264_A1880 ENOG4105C0X amino acid BCB4264_A1890 ENOG410849A acetyltransferase, (GNAT) family BCB4264_A1894 ENOG4107RHR regulatoR BCB4264_A1896 ENOG4105D9N nucleoside BCB4264_A1897 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCB4264_A1903 ENOG410811B TRANSCRIPTIONal BCB4264_A1906 ENOG4107RAQ aminopeptidase BCB4264_A1908 ENOG4107R16 Multicopper oxidase BCB4264_A1917 ENOG4108T5E Copper resistance protein BCB4264_A1918 ENOG4105KTB nuclear export factor GLE1 BCB4264_A1919 ENOG4107RT3 EamA-like transporter family BCB4264_A1920 ENOG4105GZI Transcriptional regulator BCB4264_A1921 ENOG4108Z40 Transcriptional regulator BCB4264_A1922 ENOG4107ZXU DSBA oxidoreductase BCB4264_A1923 ENOG4108TVJ Nitroreductase BCB4264_A1925 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCB4264_A1926 ENOG4106F5Q Membrane BCB4264_A1927 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCB4264_A1930 ENOG4105CKI cobalamin synthesis protein BCB4264_A1932 ENOG4105C0Z ABC transporter BCB4264_A1933 ENOG4108IV0 ABC, transporter BCB4264_A1934 ENOG4105C32 Amino acid ABC transporter (Permease) BCB4264_A1936 ENOG4105EGI Transcriptional regulator BCB4264_A1943 ENOG4105C4M (Ubiquinol oxidase) subunit I BCB4264_A1944 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCB4264_A1945 ENOG4108JJ9 ABC, transporter BCB4264_A1946 ENOG4108JJ8 (ABC) transporter BCB4264_A1948 ENOG4105K64 Glycosyl transferase, family 2 BCB4264_A1950 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCB4264_A1961 ENOG4105BZ1 (ABC) transporter BCB4264_A1962 ENOG4105EFI regulatoR BCB4264_A1963 ENOG4105BZU Histidine kinase BCB4264_A1965 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCB4264_A1966 ENOG4108ZJ4 polysaccharide deacetylase BCB4264_A1970 ENOG4105D6E homoserine dehydrogenase BCB4264_A1975 ENOG4108KGH TRANSCRIPTIONal BCB4264_A1977 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A1978 ENOG4105BZU Histidine kinase BCB4264_A1979 ENOG4107VMI polysaccharide deacetylase BCB4264_A1981 ENOG4105KT7 mgtC SapB transporter BCB4264_A1982 ENOG4105VRR gCN5-related N-acetyltransferase BCB4264_A1984 ENOG4105DUU IucA IucC family protein BCB4264_A1985 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A1988 ENOG4108WBH protein TIM barrel BCB4264_A1989 ENOG4105YWU small acid-soluble spore protein BCB4264_A1991 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCB4264_A1992 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A2002 ENOG4105KRN Transcriptional regulator, abrb family BCB4264_A2004 ENOG4105YVS arsR family transcriptional regulator BCB4264_A2005 ENOG4105CPC Aldo Keto reductase BCB4264_A2006 ENOG4107XZQ multidrug resistance protein BCB4264_A2011 ENOG4105C8Q Methyl-accepting chemotaxis BCB4264_A2014 ENOG4108K88 Membrane BCB4264_A2015 ENOG4108WPJ Ferritin-like domain BCB4264_A2018 ENOG4105DEN Luciferase family BCB4264_A2021 ENOG4105VMI -acetyltransferase BCB4264_A2022 ENOG4107QM2 Aldo Keto reductase BCB4264_A2023 ENOG4105CKI cobalamin synthesis protein BCB4264_A2025 ENOG4105DSE periplasmic solute binding protein BCB4264_A2027 ENOG4105K4T epimerase BCB4264_A2029 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCB4264_A2038 ENOG4107T5V SNARE associated Golgi BCB4264_A2041 ENOG4108PJD permease BCB4264_A2043 ENOG4108S4H thioesterase Superfamily protein BCB4264_A2045 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCB4264_A2049 ENOG4105SXS Protein of unknown function (DUF456) BCB4264_A2050 ENOG4105C37 (CBS) domain BCB4264_A2054 ENOG4108Z7R Chaperone CsaA BCB4264_A2057 ENOG4108ZRV stage ii sporulation protein p BCB4264_A2059 ENOG4108VXD carboxy-peptidase BCB4264_A2061 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCB4264_A2065 ENOG4108ZRV stage ii sporulation protein p BCB4264_A2067 ENOG4108X4Q Hydrolase BCB4264_A2070 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCB4264_A2073 ENOG41087PP glycosyltransferase MGT family BCB4264_A2074 ENOG4108JYZ YitT family BCB4264_A2075 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A2081 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCB4264_A2085 ENOG4106PAW secretion accessory protein EsaA YueB BCB4264_A2087 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BCB4264_A2088 ENOG4108MGT Required for secretion of EsxA and EsxB BCB4264_A2111 ENOG4105KBJ sporulation protein ytfj BCB4264_A2116 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCB4264_A2120 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BCB4264_A2121 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCB4264_A2123 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCB4264_A2124 ENOG4105EMN RNA polymerase sigma factor BCB4264_A2127 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BCB4264_A2129 ENOG4105CNW domain protein BCB4264_A2131 ENOG4108V06 Glutathione peroxidase BCB4264_A2134 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCB4264_A2136 ENOG4108IUE nitrate reductase beta subunit BCB4264_A2137 ENOG4105R3A Nitrate reductase BCB4264_A2139 ENOG4107V6Q Cyclic nucleotide-binding domain BCB4264_A2140 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCB4264_A2141 ENOG4105D06 uba thif-type nad fad binding protein BCB4264_A2142 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCB4264_A2143 ENOG4108ZAF Molybdopterin BCB4264_A2148 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCB4264_A2149 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCB4264_A2150 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCB4264_A2151 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BCB4264_A2152 ENOG4108IFG nitrite reductase, (NAD(P)H) BCB4264_A2153 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BCB4264_A2160 ENOG4105MCT stage V sporulation protein S BCB4264_A2163 ENOG4105DQ6 Transposase BCB4264_A2164 ENOG4105DQ6 Transposase BCB4264_A2173 ENOG4105C5H ABC transporter BCB4264_A2176 ENOG4108UUM single-stranded DNA-binding protein BCB4264_A2180 ENOG4107YX5 Pfam:DUF548 BCB4264_A2181 ENOG4105C75 arginyL-tRNA synthetase BCB4264_A2186 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BCB4264_A2191 ENOG4105C5S asparaginyl-tRNA synthetase BCB4264_A2192 ENOG4105BZW Glycerate kinase BCB4264_A2194 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A2195 ENOG41062D9 Histidine kinase BCB4264_A2198 ENOG4105C8J )-transporter BCB4264_A2202 ENOG4107XGZ Hydrolase BCB4264_A2203 ENOG4105CY2 Citrate transporter BCB4264_A2207 ENOG4105KD7 acetyltransferase BCB4264_A2209 ENOG4105VMP Transcriptional regulator BCB4264_A2210 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCB4264_A2215 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCB4264_A2218 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCB4264_A2219 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BCB4264_A2221 ENOG4107RVG penicillin-binding protein BCB4264_A2222 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BCB4264_A2223 ENOG4105E9Q Acyl-transferase BCB4264_A2224 ENOG4108UT2 hemolysin iii BCB4264_A2226 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCB4264_A2228 ENOG4108RCR degv family BCB4264_A2231 ENOG4108KF3 Electron transport protein SCO1 SenC BCB4264_A2232 ENOG4107Y70 Heat shock protein BCB4264_A2233 ENOG4105CAQ asparagine synthetase BCB4264_A2236 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BCB4264_A2237 ENOG4108MES Periplasmic binding protein BCB4264_A2238 ENOG4105F0I Aminotransferase BCB4264_A2243 ENOG4105D8X mechanosensitive ion channel BCB4264_A2244 ENOG4105BZU Histidine kinase BCB4264_A2245 ENOG4105WH1 Two component transcriptional regulator luxr family BCB4264_A2246 ENOG4106KNT transcriptional regulator BCB4264_A2247 ENOG4107ZY0 Phenazine biosynthesis-like protein BCB4264_A2250 ENOG4105DQ6 Transposase BCB4264_A2253 ENOG4105CMG Carbohydrate kinase BCB4264_A2254 ENOG4105C6Z Gluconate BCB4264_A2256 ENOG4108YV3 Protein of unknown function (DUF2711) BCB4264_A2262 ENOG4108IJ8 ABC transporter BCB4264_A2263 ENOG4105E90 ABC transporter BCB4264_A2270 ENOG4105C37 (CBS) domain BCB4264_A2275 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCB4264_A2278 ENOG4107S4Y M20 DapE family protein YgeY BCB4264_A2279 ENOG4108TSC N-acetyltransferase BCB4264_A2280 ENOG4108JUB Transcriptional regulator BCB4264_A2281 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCB4264_A2290 ENOG410841Q phosphoesterase PA-phosphatase related protein BCB4264_A2293 ENOG4105SZ6 Thioredoxin BCB4264_A2301 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCB4264_A2312 ENOG4105BZ4 penicillin-binding protein BCB4264_A2313 ENOG4105CZM Major Facilitator BCB4264_A2314 ENOG4105W8X HesB YadR YfhF-family protein BCB4264_A2316 ENOG4105DXD 2-methylcitrate dehydratase BCB4264_A2317 ENOG4105CR4 methylisocitrate lyase BCB4264_A2318 ENOG4105C1G acyl-Coa dehydrogenase BCB4264_A2319 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCB4264_A2321 ENOG4105N14 lysine exporter protein LysE YggA BCB4264_A2322 ENOG4105E39 Enoyl-CoA hydratase BCB4264_A2325 ENOG4107RFY SbcCD D subunit BCB4264_A2326 ENOG4105EYH Exonuclease BCB4264_A2332 ENOG4105FCD Major Facilitator BCB4264_A2333 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCB4264_A2334 ENOG4105E4F Isochorismate synthase BCB4264_A2335 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCB4264_A2336 ENOG4105WQI isochorismatase BCB4264_A2337 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A2338 ENOG4105WQT MbtH domain protein BCB4264_A2339 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCB4264_A2342 ENOG4105K70 DNA-binding protein BCB4264_A2346 ENOG4105BZG amino acid carrier protein BCB4264_A2353 ENOG4105FE9 pseudouridine synthase BCB4264_A2354 ENOG4105C22 threonyL-tRNA synthetase BCB4264_A2355 ENOG4105C19 ABC transporter BCB4264_A2366 ENOG41081I9 integral membrane protein BCB4264_A2368 ENOG4108Y4K DNA-binding transcriptional activator BCB4264_A2370 ENOG4107RCM Releases the N-terminal proline from various substrates (By similarity) BCB4264_A2372 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCB4264_A2374 ENOG4105EYF MMPL domain protein BCB4264_A2378 ENOG4105WCN acetyltransferase BCB4264_A2383 ENOG4105C1Q protoporphyrinogen oxidase BCB4264_A2385 ENOG41068WN BCB4264_A2391 ENOG4107V2S Transcriptional regulator BCB4264_A2392 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCB4264_A2396 ENOG4105DND Transcriptional regulator BCB4264_A2397 ENOG4108RPX mosc domain containing protein BCB4264_A2400 ENOG4105BZ1 (ABC) transporter BCB4264_A2401 ENOG4105BZ1 (ABC) transporter BCB4264_A2410 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BCB4264_A2411 ENOG4108KPJ rna polymerase sigma factor BCB4264_A2416 ENOG4105F32 YngK protein BCB4264_A2421 ENOG4105RD7 BadF BadG BcrA BcrD BCB4264_A2422 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BCB4264_A2424 ENOG4105C7B Threonine dehydratase BCB4264_A2425 ENOG4108INS Transcriptional regulator BCB4264_A2428 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCB4264_A2430 ENOG4105C1J atp-dependent rna helicase BCB4264_A2434 ENOG4108IG5 Transcriptional regulator BCB4264_A2437 ENOG41088CC tellurite resistance protein tehB BCB4264_A2439 ENOG4108I0C methyltransferase BCB4264_A2440 ENOG4107RA9 decarboxylase BCB4264_A2441 ENOG41090HR transcriptional regulator BCB4264_A2447 ENOG4105CIN aminoacyl-histidine dipeptidase BCB4264_A2453 ENOG4105KRN Transcriptional regulator, abrb family BCB4264_A2455 ENOG4105EJ9 Membrane BCB4264_A2456 ENOG4105EQK -acetyltransferase BCB4264_A2464 ENOG4105W8Z 4'-phosphopantetheinyl transferase BCB4264_A2483 ENOG4105EJQ L-serine dehydratase BCB4264_A2484 ENOG4105C44 Serine transporter BCB4264_A2489 ENOG4105F6S Spore photoproduct lyase BCB4264_A2490 ENOG4108NHD germination protein BCB4264_A2491 ENOG4108NHD germination protein BCB4264_A2492 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCB4264_A2493 ENOG4105CNI cell division protein FtsW BCB4264_A2496 ENOG4105CJW magnesium transporter BCB4264_A2498 ENOG4107RVG penicillin-binding protein BCB4264_A2501 ENOG4107RF6 penicillin-binding protein BCB4264_A2502 ENOG4107RF6 penicillin-binding protein BCB4264_A2504 ENOG4105DIN metallophosphoesterase BCB4264_A2506 ENOG4105CJ1 ABC, transporter BCB4264_A2508 ENOG4107Z3H Transcriptional regulator, TetR family BCB4264_A2511 ENOG4105C1G acyl-Coa dehydrogenase BCB4264_A2512 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCB4264_A2513 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCB4264_A2514 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCB4264_A2515 ENOG4105E39 Enoyl-CoA hydratase BCB4264_A2516 ENOG4107QX3 carboxylase BCB4264_A2517 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCB4264_A2521 ENOG4105DBI uridine monophosphokinase BCB4264_A2523 ENOG4105DZ1 carboxypeptidase BCB4264_A2527 ENOG4105T9C HD domain BCB4264_A2529 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCB4264_A2533 ENOG4105DQ6 Transposase BCB4264_A2535 ENOG41075H3 AraC family transcriptional regulator BCB4264_A2541 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCB4264_A2546 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BCB4264_A2547 ENOG4105KVH Transcriptional regulator BCB4264_A2558 ENOG4105EFA 4-hydroxyphenylacetate BCB4264_A2561 ENOG4105CPQ Dehydrogenase BCB4264_A2563 ENOG410900G Protein of unknown function (DUF421) BCB4264_A2566 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BCB4264_A2567 ENOG4105DK7 lysyl-tRNA synthetase BCB4264_A2580 ENOG4105D6E homoserine dehydrogenase BCB4264_A2582 ENOG4105CPF Cell wall formation (By similarity) BCB4264_A2584 ENOG4105ETU transcriptional activator (TenA BCB4264_A2589 ENOG4105VTR Integrase BCB4264_A2600 ENOG4105KRN Transcriptional regulator, abrb family BCB4264_A2607 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BCB4264_A2621 ENOG4105CAR Terminase, large subunit BCB4264_A2623 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCB4264_A2637 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BCB4264_A2639 ENOG4108QY0 Membrane BCB4264_A2658 ENOG410667J hydrolase BCB4264_A2659 ENOG4105BZU Histidine kinase BCB4264_A2660 ENOG4107RF6 penicillin-binding protein BCB4264_A2666 ENOG4108JJB ABC transporter BCB4264_A2669 ENOG4108HGU Histidine kinase BCB4264_A2673 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A2674 ENOG4105GR3 Histidine kinase BCB4264_A2675 ENOG4105CB2 alcohol dehydrogenase BCB4264_A2676 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCB4264_A2677 ENOG4105CJN penicillin-binding protein BCB4264_A2685 ENOG4107TXC Transcriptional regulator BCB4264_A2686 ENOG4107Y80 Major Facilitator superfamily BCB4264_A2689 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCB4264_A2694 ENOG4107Y9U Membrane BCB4264_A2698 ENOG4105EGD dinuclear metal center protein, YbgI family BCB4264_A2703 ENOG4105FCD Major Facilitator BCB4264_A2705 ENOG4105E09 nadh pyrophosphatase BCB4264_A2706 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCB4264_A2710 ENOG4105KME endoribonuclease L-psp BCB4264_A2711 ENOG4108XI2 Domain of unknown function (DUF1963) BCB4264_A2716 ENOG4108NRW Phospholipase, patatin family BCB4264_A2717 ENOG4105KWG Pfam:DUF1696 BCB4264_A2719 ENOG4108YYS metal-dependent hydrolase (By similarity) BCB4264_A2722 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BCB4264_A2724 ENOG4105PKS Excinuclease abc c subunit domain protein BCB4264_A2732 ENOG4107VFR oxidoreductase BCB4264_A2738 ENOG4105PAD Hydrolase BCB4264_A2741 ENOG4108IUM Glycogen debranching enzyme BCB4264_A2743 ENOG4105CGH 5'-nucleotidase BCB4264_A2746 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCB4264_A2747 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCB4264_A2748 ENOG4105FDR Membrane BCB4264_A2749 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A2759 ENOG4105MSI germination protein ypeb BCB4264_A2765 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BCB4264_A2766 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BCB4264_A2767 ENOG4107Z3H Transcriptional regulator, TetR family BCB4264_A2772 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCB4264_A2776 ENOG4105E98 transcriptional regulator DeoR family BCB4264_A2779 ENOG41062ES Transcriptional regulator BCB4264_A2783 ENOG4107QKR Dehydrogenase BCB4264_A2785 ENOG4107RUY (E1 component), alpha subunit BCB4264_A2787 ENOG4105E1F short-chain dehydrogenase reductase BCB4264_A2788 ENOG4105RHY Pfam:UPF0157 BCB4264_A2795 ENOG4107SQ8 Glycine betaine BCB4264_A2796 ENOG4108IJ7 Glycine betaine BCB4264_A2798 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCB4264_A2801 ENOG4105E66 phosphoriboisomerase A BCB4264_A2802 ENOG41082BV acetyltransferase BCB4264_A2803 ENOG4108M1A Chitin-binding protein BCB4264_A2809 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCB4264_A2810 ENOG4105MSB protein, conserved in bacteria BCB4264_A2820 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BCB4264_A2823 ENOG4105EEM helicase BCB4264_A2826 ENOG4105C9U ATP-dependent DNA helicase RecQ BCB4264_A2838 ENOG4108M1A Chitin-binding protein BCB4264_A2842 ENOG4105BZG amino acid carrier protein BCB4264_A2843 ENOG4105C26 Dehydrogenase BCB4264_A2844 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCB4264_A2845 ENOG4105CTU Proline racemase BCB4264_A2846 ENOG4105CTU Proline racemase BCB4264_A2849 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCB4264_A2856 ENOG4105DCI Phosphohydrolase BCB4264_A2857 ENOG4107T5V SNARE associated Golgi BCB4264_A2859 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCB4264_A2863 ENOG4105DTQ mandelate racemase muconate lactonizing BCB4264_A2866 ENOG4107SET aldo keto reductase BCB4264_A2873 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCB4264_A2875 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCB4264_A2876 ENOG4105BZU Histidine kinase BCB4264_A2877 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A2882 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BCB4264_A2886 ENOG4105EPR degv family BCB4264_A2898 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCB4264_A2899 ENOG4106K7D Major facilitator family transporter BCB4264_A2903 ENOG4107BMA Transglycosylase associated protein BCB4264_A2906 ENOG41089UC methyltransferase, type 11 BCB4264_A2916 ENOG4105CHM Aminotransferase BCB4264_A2919 ENOG4108ZMI UPF0477 protein BCB4264_A2927 ENOG4105C02 permease BCB4264_A2929 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCB4264_A2930 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCB4264_A2931 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCB4264_A2932 ENOG4105D7T ABC transporter BCB4264_A2939 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCB4264_A2946 ENOG4107VC0 DNA alkylation repair enzyme BCB4264_A2947 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BCB4264_A2948 ENOG4107VMI polysaccharide deacetylase BCB4264_A2950 ENOG4108ZCF integral membrane protein BCB4264_A2951 ENOG4105E0M Sulfatase BCB4264_A2952 ENOG4105C5H ABC transporter BCB4264_A2953 ENOG4105EYF MMPL domain protein BCB4264_A2954 ENOG41082JN Transcriptional regulator BCB4264_A2958 ENOG4105CIH Imidazole acetol-phosphate transaminase BCB4264_A2959 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BCB4264_A2960 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCB4264_A2968 ENOG41069ER domain protein BCB4264_A2970 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCB4264_A2971 ENOG4105DNP FAD linked oxidase domain protein BCB4264_A2977 ENOG4105F5R ABC transporter BCB4264_A2978 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCB4264_A2980 ENOG4105DKT Transcriptional regulator BCB4264_A2981 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BCB4264_A2983 ENOG41061GT Aldolase BCB4264_A2988 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCB4264_A2995 ENOG4105II7 pyrroline-5-carboxylate reductase BCB4264_A2997 ENOG4107258 Transcriptional regulator BCB4264_A3000 ENOG4105ECK Fatty Acid Desaturase BCB4264_A3002 ENOG4107RBI VanW family BCB4264_A3003 ENOG4105G6Z alkaline phosphatase BCB4264_A3005 ENOG4105VMP Transcriptional regulator BCB4264_A3009 ENOG41068WN BCB4264_A3015 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCB4264_A3019 ENOG4105CKK Glycosyl transferase, family 2 BCB4264_A3025 ENOG4105C8Y Acetylornithine aminotransferase BCB4264_A3034 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCB4264_A3038 ENOG4108IBT Inherit from COG: transposase BCB4264_A3041 ENOG4105DQ6 Transposase BCB4264_A3044 ENOG4108TVJ Nitroreductase BCB4264_A3045 ENOG4105FS7 Transcriptional regulator BCB4264_A3048 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCB4264_A3049 ENOG4105WEC Molybdate metabolism regulator BCB4264_A3050 ENOG4105CMR udp-glucose 4-epimerase BCB4264_A3053 ENOG4108DMH HTH_ARAC BCB4264_A3054 ENOG4108XET gCN5-related N-acetyltransferase BCB4264_A3061 ENOG4107XJU UPF0178 protein BCB4264_A3067 ENOG410635A Membrane BCB4264_A3071 ENOG4108IQI permease BCB4264_A3073 ENOG4105F1N DNA alkylation repair BCB4264_A3080 ENOG4107RF6 penicillin-binding protein BCB4264_A3082 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BCB4264_A3088 ENOG4105P4J Allophanate hydrolase, subunit 1 BCB4264_A3089 ENOG4107258 Transcriptional regulator BCB4264_A3091 ENOG4106N3A copper homeostasis protein cutc BCB4264_A3092 ENOG4108ZHR arsR family transcriptional regulator BCB4264_A3094 ENOG4105FDT acyl-CoA dehydrogenase BCB4264_A3099 ENOG4105DWD nucleoside recognition domain protein BCB4264_A3108 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCB4264_A3114 ENOG4105E2A Dehydrogenase BCB4264_A3115 ENOG4108IJ0 Aspartate ammonia-lyase BCB4264_A3116 ENOG4105HDK L-asparaginase BCB4264_A3117 ENOG4108IMY Transcriptional regulator BCB4264_A3120 ENOG4108B31 Spore germination protein BCB4264_A3122 ENOG4105BZU Histidine kinase BCB4264_A3127 ENOG41075H3 AraC family transcriptional regulator BCB4264_A3129 ENOG4105YWU small acid-soluble spore protein BCB4264_A3130 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCB4264_A3131 ENOG4105CUB amino acid BCB4264_A3132 ENOG4105II7 pyrroline-5-carboxylate reductase BCB4264_A3134 ENOG4105C6K Malic enzyme BCB4264_A3136 ENOG4108NHD germination protein BCB4264_A3137 ENOG4108Q8B Spore germination protein BCB4264_A3142 ENOG4105CSV Glutaminase BCB4264_A3146 ENOG4106A3M Cytochrome p-450 BCB4264_A3149 ENOG4105CGH 5'-nucleotidase BCB4264_A3151 ENOG4105CHJ isochorismatase hydrolase BCB4264_A3161 ENOG4105F6J Alpha beta hydrolase fold BCB4264_A3164 ENOG4108606 TspO/MBR family BCB4264_A3165 ENOG4105CVP deoxyribo-dipyrimidine photolyase BCB4264_A3167 ENOG4108US0 Transcription regulator that can specifically activate or repress expression of target genes (By similarity) BCB4264_A3173 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BCB4264_A3176 ENOG4108TWJ NADH dehydrogenase subunit 5 BCB4264_A3177 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCB4264_A3178 ENOG4107VMI polysaccharide deacetylase BCB4264_A3179 ENOG4105KY5 gCN5-related N-acetyltransferase BCB4264_A3180 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCB4264_A3185 ENOG4105Z7P Acetyltransferase (GNAT) family BCB4264_A3186 ENOG4108SY2 LMWPc BCB4264_A3187 ENOG4105D6J arsenicaL-resistance protein BCB4264_A3188 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCB4264_A3189 ENOG41085FC arsR family transcriptional regulator BCB4264_A3191 ENOG4105NAE bifunctional deaminase-reductase domain protein BCB4264_A3193 ENOG4107P5I polyketide synthase BCB4264_A3194 ENOG4108IG5 Transcriptional regulator BCB4264_A3195 ENOG4105CHR reductase BCB4264_A3196 ENOG4108YXU transcriptional regulator AsnC family BCB4264_A3207 ENOG4105C44 Serine transporter BCB4264_A3210 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCB4264_A3211 ENOG4105DUM transcriptional regulator, lysR family BCB4264_A3212 ENOG4105DWP Membrane BCB4264_A3213 ENOG4105N0V mono-oxygenase ydhR BCB4264_A3221 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A3222 ENOG41062D9 Histidine kinase BCB4264_A3228 ENOG4105WH1 Two component transcriptional regulator luxr family BCB4264_A3231 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCB4264_A3232 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCB4264_A3235 ENOG4105K6H D-cysteine desulfhydrase BCB4264_A3237 ENOG4105E0Y RtcB Protein BCB4264_A3239 ENOG4105JQZ Methyltransferase BCB4264_A3240 ENOG4105JQZ Methyltransferase BCB4264_A3244 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCB4264_A3248 ENOG4105BZU Histidine kinase BCB4264_A3251 ENOG4108U05 Transcriptional regulator BCB4264_A3252 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BCB4264_A3254 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCB4264_A3260 ENOG4108JQ1 Dehydrogenase BCB4264_A3261 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BCB4264_A3268 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCB4264_A3298 ENOG4108VXD carboxy-peptidase BCB4264_A3299 ENOG4105PNM synthesis protein BCB4264_A3301 ENOG4108ISG Major Facilitator BCB4264_A3304 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCB4264_A3305 ENOG4105CZM Major Facilitator BCB4264_A3308 ENOG4105CRW Short chain fatty acid transporter BCB4264_A3310 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCB4264_A3323 ENOG4108K8S endonuclease I BCB4264_A3326 ENOG41067QW Transcriptional regulator BCB4264_A3328 ENOG4108Z66 YbaK ebsC protein BCB4264_A3329 ENOG4105CUT histidyl-tRNA synthetase BCB4264_A3332 ENOG4105KVH Transcriptional regulator BCB4264_A3333 ENOG4108RCM Nitroreductase BCB4264_A3339 ENOG4108PSK reductase BCB4264_A3353 ENOG4105C31 Tryptophanyl-tRNA synthetase BCB4264_A3354 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BCB4264_A3362 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BCB4264_A3364 ENOG4105EV4 Multidrug resistance protein mdtH BCB4264_A3370 ENOG4105C37 (CBS) domain BCB4264_A3373 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCB4264_A3374 ENOG4105FAW cDP-glucose 4,6-dehydratase BCB4264_A3381 ENOG4105DDN Pentapeptide repeat-containing protein BCB4264_A3382 ENOG4105XDF Protein of unknown function (DUF1272) BCB4264_A3383 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCB4264_A3384 ENOG4105CMG Carbohydrate kinase BCB4264_A3385 ENOG4105C6Z Gluconate BCB4264_A3386 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCB4264_A3389 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCB4264_A3390 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCB4264_A3394 ENOG4105C8Q Methyl-accepting chemotaxis BCB4264_A3396 ENOG4108UX3 '-nucleotidase BCB4264_A3397 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCB4264_A3398 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BCB4264_A3399 ENOG4105KVH Transcriptional regulator BCB4264_A3403 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCB4264_A3404 ENOG4105CHH sulfate transporter BCB4264_A3407 ENOG4105C44 Serine transporter BCB4264_A3412 ENOG4108TZY GntR Family Transcriptional Regulator BCB4264_A3413 ENOG4105D9R oxidoreductase BCB4264_A3421 ENOG4105JAB phenazine biosynthesis protein, phzf family BCB4264_A3423 ENOG4105CHR reductase BCB4264_A3425 ENOG4105KNA -acetyltransferase BCB4264_A3427 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCB4264_A3428 ENOG4105KVH Transcriptional regulator BCB4264_A3431 ENOG4108ZJ4 polysaccharide deacetylase BCB4264_A3442 ENOG4105DQ6 Transposase BCB4264_A3445 ENOG4105CNA YD repeat protein BCB4264_A3446 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCB4264_A3452 ENOG4105H3G oxidoreductase BCB4264_A3467 ENOG4108TN2 lmbE family BCB4264_A3469 ENOG4107R3E Citrate transporter BCB4264_A3472 ENOG4108MES Periplasmic binding protein BCB4264_A3473 ENOG4105EHG Permease protein BCB4264_A3474 ENOG4105DQ5 transport system permease protein BCB4264_A3475 ENOG4105NX3 Membrane BCB4264_A3479 ENOG4107CUJ Protein of unknown function (DUF2690) BCB4264_A3482 ENOG4107V2S Transcriptional regulator BCB4264_A3486 ENOG4105C98 muts2 protein BCB4264_A3487 ENOG4105E5K Alpha-amylase BCB4264_A3488 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCB4264_A3489 ENOG4105DPN Oligoendopeptidase f BCB4264_A3491 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BCB4264_A3495 ENOG4105FFC UPF0187 protein BCB4264_A3498 ENOG4108A04 Beta-lactamase BCB4264_A3503 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCB4264_A3506 ENOG41082BM Transcriptional regulator, arsr family BCB4264_A3507 ENOG4105CIS alcohol dehydrogenase BCB4264_A3515 ENOG4105CQB FAD linked oxidase domain protein BCB4264_A3520 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCB4264_A3523 ENOG4107TPS domain protein BCB4264_A3524 ENOG4105CEP NADH dehydrogenase BCB4264_A3526 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCB4264_A3528 ENOG4108IAJ Nad-dependent epimerase dehydratase BCB4264_A3529 ENOG4105FAW cDP-glucose 4,6-dehydratase BCB4264_A3604 ENOG4105GR3 Histidine kinase BCB4264_A3605 ENOG4105BZU Histidine kinase BCB4264_A3608 ENOG41069ER domain protein BCB4264_A3617 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BCB4264_A3621 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BCB4264_A3630 ENOG4105BZU Histidine kinase BCB4264_A3635 ENOG4105BZU Histidine kinase BCB4264_A3637 ENOG4105KT7 mgtC SapB transporter BCB4264_A3639 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCB4264_A3641 ENOG41073R8 VanW family BCB4264_A3643 ENOG4108R1P BCB4264_A3647 ENOG4105VEQ Cold shock protein BCB4264_A3651 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCB4264_A3655 ENOG410904N short-chain dehydrogenase reductase BCB4264_A3657 ENOG4106IQC argininosuccinate lyase BCB4264_A3660 ENOG4108IA2 Sodium pantothenate symporter BCB4264_A3662 ENOG4105C26 Dehydrogenase BCB4264_A3663 ENOG4105CHR reductase BCB4264_A3665 ENOG4105EWU Squalene--hopene cyclase BCB4264_A3667 ENOG4105FR1 rard protein BCB4264_A3668 ENOG410696E Membrane BCB4264_A3671 ENOG4105D1F ATP-binding protein BCB4264_A3673 ENOG4108ZAF Molybdopterin BCB4264_A3674 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCB4264_A3675 ENOG4105D06 uba thif-type nad fad binding protein BCB4264_A3676 ENOG4105TMB Formate nitrite transporter BCB4264_A3678 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCB4264_A3679 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCB4264_A3681 ENOG4108JB9 formate dehydrogenase BCB4264_A3682 ENOG4105E1K spore germination protein BCB4264_A3685 ENOG4105CUB amino acid BCB4264_A3697 ENOG4107QJT sodium dicarboxylate symporter BCB4264_A3698 ENOG4108KGH TRANSCRIPTIONal BCB4264_A3700 ENOG4105EMN RNA polymerase sigma factor BCB4264_A3702 ENOG4105CIG ABC transporter BCB4264_A3704 ENOG4105D9R oxidoreductase BCB4264_A3706 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCB4264_A3707 ENOG4105K4P CoA-binding domain protein BCB4264_A3708 ENOG4105C0H protease BCB4264_A3709 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A3711 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCB4264_A3712 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BCB4264_A3713 ENOG4105W8X HesB YadR YfhF-family protein BCB4264_A3719 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCB4264_A3720 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCB4264_A3723 ENOG4108JJA ABC, transporter BCB4264_A3724 ENOG4108I0Z Aconitate hydratase BCB4264_A3730 ENOG4105E5W Transporter BCB4264_A3732 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCB4264_A3736 ENOG4107F3J Amp-dependent synthetase and ligase BCB4264_A3737 ENOG4107ZYJ bioY protein BCB4264_A3738 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A3747 ENOG4107AYK membrAne BCB4264_A3749 ENOG4105BZU Histidine kinase BCB4264_A3750 ENOG4105FBA Phospholipase Carboxylesterase BCB4264_A3751 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCB4264_A3752 ENOG4105CK7 Sodium proline symporter BCB4264_A3754 ENOG4105CBC glutamate synthase BCB4264_A3755 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCB4264_A3756 ENOG4108VJ1 Transcriptional regulator (CarD family BCB4264_A3757 ENOG4108903 Formimidoylglutamase BCB4264_A3768 ENOG4107QIV Cytochrome c biogenesis protein BCB4264_A3771 ENOG4105CH2 amidohydrolase BCB4264_A3773 ENOG4105CJ1 ABC, transporter BCB4264_A3776 ENOG4107RSM transcriptional regulator BCB4264_A3777 ENOG4105VAW lrga family BCB4264_A3778 ENOG41067MG lrgb family BCB4264_A3779 ENOG4108Z4K mutator MutT protein BCB4264_A3786 ENOG4105BZ1 (ABC) transporter BCB4264_A3787 ENOG4105BZ1 (ABC) transporter BCB4264_A3795 ENOG4108HW3 (ABC) transporter BCB4264_A3796 ENOG4105CGH 5'-nucleotidase BCB4264_A3798 ENOG4108SVB resolvase BCB4264_A3802 ENOG4105K7K Transcriptional regulator BCB4264_A3803 ENOG4105C5F glutamine synthetase BCB4264_A3804 ENOG4105KV4 Transcriptional regulator BCB4264_A3805 ENOG4105CXI aluminum resistance protein BCB4264_A3806 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCB4264_A3807 ENOG4105EN6 Membrane BCB4264_A3809 ENOG4106F1P AAA ATPase, central domain protein BCB4264_A3815 ENOG41069ER domain protein BCB4264_A3816 ENOG4105DM4 PTS System BCB4264_A3817 ENOG4105DE4 1-phosphofructokinase BCB4264_A3818 ENOG4105E98 transcriptional regulator DeoR family BCB4264_A3819 ENOG4107QW4 alcohol dehydrogenase BCB4264_A3820 ENOG4108SJC Membrane BCB4264_A3823 ENOG4105C85 amino acid BCB4264_A3826 ENOG4105TMB Formate nitrite transporter BCB4264_A3827 ENOG4105K70 DNA-binding protein BCB4264_A3829 ENOG4105C59 p-type ATPase BCB4264_A3830 ENOG410681U heavy metal transport detoxification protein BCB4264_A3831 ENOG4105VPX protein, conserved in bacteria BCB4264_A3833 ENOG4105NIV Esterase BCB4264_A3834 ENOG4105E0A ABC, transporter BCB4264_A3839 ENOG4105CGK Exodeoxyribonuclease III BCB4264_A3841 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCB4264_A3842 ENOG4105D03 DNA-3-methyladenine glycosylase II BCB4264_A3847 ENOG4105BZU Histidine kinase BCB4264_A3855 ENOG41067MG lrgb family BCB4264_A3857 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BCB4264_A3858 ENOG4107YEI lmbE family BCB4264_A3862 ENOG4105F0V Cell wall hydrolase BCB4264_A3864 ENOG4105E0M Sulfatase BCB4264_A3865 ENOG410890F Dynamin family BCB4264_A3872 ENOG4105DQU oxidoreductase, subunit beta BCB4264_A3873 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCB4264_A3874 ENOG4108IGT Dipeptidase BCB4264_A3875 ENOG4105MCT stage V sporulation protein S BCB4264_A3876 ENOG4105D48 metallophosphoesterase BCB4264_A3880 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCB4264_A3883 ENOG4105XZV Protein of unknown function (DUF3243) BCB4264_A3884 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCB4264_A3888 ENOG4105UIB (ABC) transporter BCB4264_A3889 ENOG4108JQ9 ABC transporter BCB4264_A3890 ENOG4105DIH basic membrane BCB4264_A3891 ENOG4105FDP GntR family transcriptional regulator BCB4264_A3893 ENOG4105CNU cell division protein FtsK BCB4264_A3895 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCB4264_A3897 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCB4264_A3899 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCB4264_A3900 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCB4264_A3901 ENOG4105E35 Dipicolinate synthase subunit A BCB4264_A3903 ENOG4105C1V Peptidase, M16 BCB4264_A3907 ENOG4105DTN riboflavin biosynthesis protein ribF BCB4264_A3910 ENOG4105W7A Protein of unknown function (DUF503) BCB4264_A3912 ENOG4105VHM ribosomal protein BCB4264_A3913 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCB4264_A3914 ENOG4105CHV Transcription elongation factor NusA BCB4264_A3916 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCB4264_A3918 ENOG4105DZP Membrane-associated zinc metalloprotease BCB4264_A3919 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BCB4264_A3920 ENOG4105KNE Phosphatidate cytidylyltransferase BCB4264_A3921 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BCB4264_A3923 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCB4264_A3929 ENOG4108HE4 integrase family BCB4264_A3931 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCB4264_A3932 ENOG4105C79 DNA protecting protein DprA BCB4264_A3933 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCB4264_A3936 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCB4264_A3942 ENOG4105VB6 UPF0109 protein BCB4264_A3946 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCB4264_A3947 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCB4264_A3950 ENOG4105CHR reductase BCB4264_A3951 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCB4264_A3954 ENOG4105CB5 ATP-dependent DNA helicase recG BCB4264_A3955 ENOG4105DP4 dak2 domain fusion protein ylov BCB4264_A3956 ENOG4108ZAA Alkaline-shock protein BCB4264_A3958 ENOG4105FJ0 thiamine BCB4264_A3959 ENOG4105DJV ribulose-phosphate 3-epimerase BCB4264_A3960 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BCB4264_A3961 ENOG4105D9P serine threonine protein kinase BCB4264_A3962 ENOG4108ZF3 Phosphatase BCB4264_A3964 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCB4264_A3967 ENOG4105C25 Primosomal protein n' BCB4264_A3968 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCB4264_A3972 ENOG4105DSJ YicC domain protein BCB4264_A3974 ENOG4105F23 Fibronectin-binding protein BCB4264_A3975 ENOG4105DC7 peptidase M24 BCB4264_A3993 ENOG4105C34 Pseudouridine synthase BCB4264_A3996 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BCB4264_A3998 ENOG4105DBK s4 domain protein BCB4264_A3999 ENOG41067XK integral membrane protein BCB4264_A4001 ENOG4105DFA alanine racemase domain protein BCB4264_A4002 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCB4264_A4003 ENOG4105WR5 sporulation protein, YlmC YmxH family BCB4264_A4005 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A4007 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCB4264_A4008 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCB4264_A4010 ENOG4105D4A Cell wall formation (By similarity) BCB4264_A4011 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BCB4264_A4012 ENOG4105CNI cell division protein FtsW BCB4264_A4015 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCB4264_A4016 ENOG4105CJN penicillin-binding protein BCB4264_A4017 ENOG4105CJN penicillin-binding protein BCB4264_A4025 ENOG4105KNH Nucleic acid-binding protein BCB4264_A4027 ENOG41063PX domain protein BCB4264_A4028 ENOG4105D78 K07001 NTE family protein BCB4264_A4029 ENOG4105H20 Sporulation integral membrane protein YlbJ BCB4264_A4031 ENOG4106H78 methyltransferase BCB4264_A4036 ENOG4107TB6 phosphoglycerate mutase BCB4264_A4039 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCB4264_A4050 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCB4264_A4051 ENOG4105CNI cell division protein FtsW BCB4264_A4054 ENOG4108IAB Phoh family BCB4264_A4058 ENOG4105QA2 BCB4264_A4059 ENOG4105CI3 gtp-binding protein typa BCB4264_A4061 ENOG4105ECY inositol monophosphatase BCB4264_A4065 ENOG4105CXN decarboxylase BCB4264_A4074 ENOG4105CPP Dehydrogenase, E1 component BCB4264_A4077 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCB4264_A4078 ENOG4108X4Q Hydrolase BCB4264_A4080 ENOG4105CN5 Metallo-Beta-Lactamase BCB4264_A4081 ENOG4107ZYR domain protein BCB4264_A4088 ENOG4108XRC Protein of unknown function (DUF458) BCB4264_A4090 ENOG4107IN1 Protein of unknown function (DUF1797) BCB4264_A4094 ENOG4105EPM Diguanylate phosphodiesterase BCB4264_A4095 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCB4264_A4098 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCB4264_A4100 ENOG4105UIN BCB4264_A4112 ENOG4108HGU Histidine kinase BCB4264_A4115 ENOG4105CHM Aminotransferase BCB4264_A4116 ENOG4105FKQ transcriptional regulator BCB4264_A4117 ENOG4105EG2 ABC transporter, permease BCB4264_A4119 ENOG4107FKK extracellular solute-binding protein family 1 BCB4264_A4121 ENOG4105CG3 alpha amylase, catalytic region BCB4264_A4129 ENOG4105CHU acetyl-coa acetyltransferase BCB4264_A4136 ENOG4105K7K Transcriptional regulator BCB4264_A4137 ENOG4105DTD Dehydrogenase BCB4264_A4142 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCB4264_A4148 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BCB4264_A4151 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCB4264_A4153 ENOG4105BZU Histidine kinase BCB4264_A4157 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCB4264_A4160 ENOG4105CID antiterminator BCB4264_A4162 ENOG4105FDP GntR family transcriptional regulator BCB4264_A4164 ENOG4105CE4 GlcNAc 6-P deacetylase BCB4264_A4170 ENOG4107ZE5 PPIases accelerate the folding of proteins BCB4264_A4171 ENOG4105PTM secreted protein BCB4264_A4172 ENOG4105J7I hydrolase BCB4264_A4174 ENOG4105G6R Stage v sporulation protein ae BCB4264_A4176 ENOG4105CZ3 stage V sporulation protein ad BCB4264_A4177 ENOG41090VF Stage v sporulation protein ac BCB4264_A4181 ENOG4105C8J )-transporter BCB4264_A4182 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A4184 ENOG41082AN stage II sporulation protein BCB4264_A4185 ENOG4105DZ1 carboxypeptidase BCB4264_A4186 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A4187 ENOG4105DVE abc transporter atp-binding protein BCB4264_A4194 ENOG4105D7N magnesium and cobalt transport protein CorA BCB4264_A4199 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCB4264_A4201 ENOG4105I3K Ferric uptake regulator, Fur family BCB4264_A4202 ENOG4105MZ9 stage II sporulation protein m BCB4264_A4206 ENOG4105CPC Aldo Keto reductase BCB4264_A4208 ENOG4105RHY Pfam:UPF0157 BCB4264_A4212 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCB4264_A4214 ENOG4105ETE Transcriptional regulator (LacI family BCB4264_A4215 ENOG4108YM7 Gcn5-related n-acetyltransferase BCB4264_A4220 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCB4264_A4221 ENOG4108R6K riboflavin synthase, subunit alpha BCB4264_A4226 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCB4264_A4227 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCB4264_A4230 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCB4264_A4232 ENOG4105DFD Na H antiporter BCB4264_A4233 ENOG4105CGH 5'-nucleotidase BCB4264_A4238 ENOG4105DBV ornithine carbamoyltransferase BCB4264_A4241 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BCB4264_A4244 ENOG4108IXY short-chain dehydrogenase reductase BCB4264_A4245 ENOG41069FQ Metallo-beta-lactamase superfamily BCB4264_A4246 ENOG4105II7 pyrroline-5-carboxylate reductase BCB4264_A4247 ENOG4105EJQ L-serine dehydratase BCB4264_A4254 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BCB4264_A4257 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCB4264_A4258 ENOG4105D9U N-acetyltransferase BCB4264_A4260 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCB4264_A4261 ENOG4108QEG Membrane BCB4264_A4262 ENOG4105CDA abc transporter atp-binding protein BCB4264_A4263 ENOG4105E5Q amino acid AbC transporter BCB4264_A4264 ENOG4108HW3 (ABC) transporter BCB4264_A4266 ENOG4105G7B Protein of unknown function (DUF2992) BCB4264_A4267 ENOG4105E09 nadh pyrophosphatase BCB4264_A4268 ENOG4108QY0 Membrane BCB4264_A4270 ENOG4105C7S Dehydrogenase BCB4264_A4271 ENOG4105CPP Dehydrogenase, E1 component BCB4264_A4275 ENOG4107RDP Dehydrogenase BCB4264_A4277 ENOG4108JUB Transcriptional regulator BCB4264_A4279 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCB4264_A4282 ENOG4107QQR Sporulation BCB4264_A4283 ENOG4105S1Z Stage IV sporulation protein B BCB4264_A4284 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCB4264_A4285 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BCB4264_A4286 ENOG4105DX0 Hemolysin A BCB4264_A4288 ENOG4105CTB Polyprenyl synthetase BCB4264_A4293 ENOG4108ZSR alkaline shock protein BCB4264_A4294 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCB4264_A4298 ENOG410644B Stage III sporulation protein af BCB4264_A4300 ENOG4105KQ4 Stage iii sporulation protein ad BCB4264_A4301 ENOG4108CQH stage III sporulation protein AC BCB4264_A4302 ENOG4105KR5 Stage iii sporulation protein BCB4264_A4303 ENOG4105CD2 stage iii sporulation protein aa BCB4264_A4308 ENOG4105DC7 peptidase M24 BCB4264_A4311 ENOG4105CBJ Metal-dependent enzyme BCB4264_A4313 ENOG4107YBY Hydrolase BCB4264_A4316 ENOG4105K7K Transcriptional regulator BCB4264_A4319 ENOG41082GG biotin lipoate A B protein ligase BCB4264_A4320 ENOG4105WZW rhodanese family BCB4264_A4325 ENOG41080TC multidrug resistance protein BCB4264_A4332 ENOG4105CJ1 ABC, transporter BCB4264_A4333 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A4336 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BCB4264_A4340 ENOG4105C0D helicase BCB4264_A4358 ENOG4107R6U sodium dicarboxylate symporter BCB4264_A4365 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BCB4264_A4366 ENOG4105C3R Methionine synthase BCB4264_A4370 ENOG4105C28 cystathionine BCB4264_A4371 ENOG4105C28 cystathionine BCB4264_A4375 ENOG4105C5X domain protein BCB4264_A4377 ENOG4105DKQ ROK family BCB4264_A4379 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCB4264_A4383 ENOG4105DQ6 Transposase BCB4264_A4384 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCB4264_A4385 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A4386 ENOG4105C8U phosphate abc transporter BCB4264_A4387 ENOG4105C8U phosphate abc transporter BCB4264_A4388 ENOG4105EXS phosphate abc transporter BCB4264_A4389 ENOG4107RF6 penicillin-binding protein BCB4264_A4391 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCB4264_A4397 ENOG4105N80 Ferric uptake regulator, Fur family BCB4264_A4399 ENOG4105FDK ABC transporter BCB4264_A4400 ENOG4108JYZ YitT family BCB4264_A4401 ENOG41069ZM Protein of unknown function (DUF2624) BCB4264_A4406 ENOG4105EGD dinuclear metal center protein, YbgI family BCB4264_A4409 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A4410 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCB4264_A4417 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCB4264_A4418 ENOG4105KG3 cytidine deaminase BCB4264_A4419 ENOG4107YR5 Diacylglycerol kinase BCB4264_A4421 ENOG4105CTJ Metal Dependent Phosphohydrolase BCB4264_A4422 ENOG4105C9A Phoh family BCB4264_A4424 ENOG41068P3 sporulation protein YqfC BCB4264_A4426 ENOG4105KTH gatB Yqey BCB4264_A4429 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCB4264_A4430 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCB4264_A4436 ENOG4105CSA Coproporphyrinogen iii oxidase BCB4264_A4437 ENOG4105KVH Transcriptional regulator BCB4264_A4442 ENOG4105TQK DNA polymerase iii, delta' subunit BCB4264_A4445 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCB4264_A4446 ENOG4108UK2 deaminase BCB4264_A4447 ENOG4105KQC Competence protein BCB4264_A4449 ENOG4105DXX methyltransferase BCB4264_A4451 ENOG4108WF2 Metal Dependent Phosphohydrolase BCB4264_A4453 ENOG410812S Rna-binding protein BCB4264_A4455 ENOG4105CQW ribosome biogenesis GTPase YqeH BCB4264_A4456 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCB4264_A4459 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A4463 ENOG4108TVJ Nitroreductase BCB4264_A4466 ENOG4105G6Z alkaline phosphatase BCB4264_A4467 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BCB4264_A4468 ENOG4108MUZ hydrolase BCB4264_A4475 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCB4264_A4477 ENOG4105MIR Phenylalanine 4-monooxygenase BCB4264_A4479 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCB4264_A4487 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCB4264_A4488 ENOG4108V5C ABC transporter BCB4264_A4490 ENOG4108EKI Dehydrogenase BCB4264_A4491 ENOG4105C28 cystathionine BCB4264_A4497 ENOG4107XRG penicillin-binding protein BCB4264_A4499 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BCB4264_A4501 ENOG4105CFP Peptidase U32 BCB4264_A4502 ENOG4105XYU peptidase (U32 family) BCB4264_A4503 ENOG4108VQJ O-methyltransferase BCB4264_A4504 ENOG4105HHA aminodeoxychorismate lyase BCB4264_A4508 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCB4264_A4510 ENOG4105C02 permease BCB4264_A4513 ENOG41060CR BCB4264_A4514 ENOG4105C7H Helicase, RecD TraA family BCB4264_A4516 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BCB4264_A4517 ENOG4105C3J Cysteine desulfurase BCB4264_A4519 ENOG4105D1H recombination factor protein RarA BCB4264_A4520 ENOG4108VCI transcription factor, rsfa family BCB4264_A4521 ENOG4105CUZ uba thif-type nad fad binding protein BCB4264_A4523 ENOG4105CUT histidyl-tRNA synthetase BCB4264_A4526 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCB4264_A4528 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCB4264_A4529 ENOG41076HS cation diffusion facilitator family transporter BCB4264_A4530 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCB4264_A4532 ENOG4105CKP Polysaccharide Biosynthesis Protein BCB4264_A4533 ENOG4108QG2 Membrane BCB4264_A4535 ENOG4105VIE preprotein translocase, subunit YajC BCB4264_A4538 ENOG41061AI Protein of unknown function (DUF2905) BCB4264_A4541 ENOG4108HUF Transporter BCB4264_A4547 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCB4264_A4548 ENOG4108IYU L-aspartate oxidase BCB4264_A4551 ENOG4108RPX mosc domain containing protein BCB4264_A4552 ENOG4105CQC Prephenate dehydratase BCB4264_A4555 ENOG4105C19 ABC transporter BCB4264_A4556 ENOG4105EWM Histidine kinase BCB4264_A4561 ENOG4105X36 (ribosomal) protein BCB4264_A4564 ENOG4105C03 ribonuclease BCB4264_A4567 ENOG4107QMS site-determining protein BCB4264_A4570 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCB4264_A4571 ENOG4105DFF Rod shape-determining protein mreb BCB4264_A4575 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCB4264_A4576 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BCB4264_A4578 ENOG41068KH stage VI sporulation protein D BCB4264_A4580 ENOG4105D52 delta-aminolevulinic acid dehydratase BCB4264_A4585 ENOG4105K56 Transcriptional regulator BCB4264_A4589 ENOG4108IUQ atp-dependent protease BCB4264_A4595 ENOG4108QCI YvbH-like oligomerisation region BCB4264_A4599 ENOG4105M59 Phosphodiesterase, mj0936 family BCB4264_A4600 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BCB4264_A4602 ENOG4108XJQ germination protein BCB4264_A4605 ENOG4108PCX Major Facilitator BCB4264_A4607 ENOG4105KBX Transcriptional regulator, TetR family BCB4264_A4609 ENOG4105PFC Transcriptional regulator BCB4264_A4611 ENOG4105DZC cytosine deaminase BCB4264_A4612 ENOG41067S9 phage shock protein C, PspC BCB4264_A4613 ENOG4108JCI Transcriptional regulator BCB4264_A4615 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCB4264_A4616 ENOG4108Z40 Transcriptional regulator BCB4264_A4617 ENOG4105RHA ABC transporter, permease BCB4264_A4618 ENOG4108IUX (ABC) transporter BCB4264_A4619 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCB4264_A4620 ENOG4105ER2 Ompa motb domain protein BCB4264_A4621 ENOG4105E14 MotA TolQ exbB proton channel BCB4264_A4622 ENOG4108VXD carboxy-peptidase BCB4264_A4624 ENOG4105E33 succinate dehydrogenase BCB4264_A4626 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCB4264_A4629 ENOG4105K63 Thioredoxin BCB4264_A4630 ENOG4105C10 Electron transfer flavoprotein BCB4264_A4631 ENOG4105BZJ Electron transfer flavoprotein BCB4264_A4632 ENOG41060WC Enoyl-CoA hydratase BCB4264_A4633 ENOG4107Z3H Transcriptional regulator, TetR family BCB4264_A4634 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A4636 ENOG4105J76 Periplasmic binding protein BCB4264_A4637 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCB4264_A4647 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A4650 ENOG4105DR4 Methyltransferase BCB4264_A4652 ENOG4105KFN sortase, SrtB family BCB4264_A4653 ENOG4105E0A ABC, transporter BCB4264_A4656 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCB4264_A4658 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCB4264_A4661 ENOG4105FE9 pseudouridine synthase BCB4264_A4663 ENOG4105DCG PHP domain protein BCB4264_A4670 ENOG4105C5S asparaginyl-tRNA synthetase BCB4264_A4671 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BCB4264_A4673 ENOG4108RWN rrna methyltransferase BCB4264_A4676 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCB4264_A4677 ENOG4105CW7 secretion protein, HlyD family BCB4264_A4678 ENOG4108JGH Tetr family transcriptional regulator BCB4264_A4679 ENOG4105CN9 Peptidase m42 family protein BCB4264_A4683 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCB4264_A4685 ENOG4105C22 threonyL-tRNA synthetase BCB4264_A4686 ENOG4108TDW sporulation protein YtxC BCB4264_A4691 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCB4264_A4693 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCB4264_A4694 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BCB4264_A4696 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BCB4264_A4697 ENOG4105C2M dna polymerase I BCB4264_A4698 ENOG4105BZU Histidine kinase BCB4264_A4699 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A4703 ENOG4108HMX isocitrate dehydrogenase (NADP) BCB4264_A4704 ENOG4105BZN citrate synthase BCB4264_A4706 ENOG4108REF Sporulation integral membrane protein ytvi BCB4264_A4707 ENOG4105FS0 cytoplasmic membrane protein BCB4264_A4712 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCB4264_A4713 ENOG4105C6K Malic enzyme BCB4264_A4714 ENOG4105C0B DNA polymerase III (alpha subunit) BCB4264_A4715 ENOG4105VV2 BCB4264_A4717 ENOG4105SFS phosphoesterase RecJ domain protein BCB4264_A4723 ENOG4105DC7 peptidase M24 BCB4264_A4728 ENOG4105Z7P Acetyltransferase (GNAT) family BCB4264_A4729 ENOG41082W1 Cupin 2, conserved barrel domain protein BCB4264_A4733 ENOG4107YZX Universal stress protein BCB4264_A4742 ENOG4108JYZ YitT family BCB4264_A4746 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BCB4264_A4748 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCB4264_A4749 ENOG4105KBJ sporulation protein ytfj BCB4264_A4752 ENOG4105EFZ amidohydrolase BCB4264_A4754 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCB4264_A4759 ENOG4105RQF LysR family Transcriptional regulator BCB4264_A4761 ENOG4105U5Y Transcriptional regulator BCB4264_A4763 ENOG4105C28 cystathionine BCB4264_A4772 ENOG4105EMN RNA polymerase sigma factor BCB4264_A4774 ENOG4108UW5 maltose o-acetyltransferase BCB4264_A4776 ENOG4105F1V Acetoin utilization protein BCB4264_A4777 ENOG4105W87 Cbs domain BCB4264_A4778 ENOG4105DGU Histone deacetylase BCB4264_A4781 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCB4264_A4783 ENOG4107SNB ankyrin repeat protein YahD BCB4264_A4784 ENOG4105EP9 oxidoreductase BCB4264_A4790 ENOG4105ETE Transcriptional regulator (LacI family BCB4264_A4791 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCB4264_A4795 ENOG4105C88 aminopeptidase BCB4264_A4802 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BCB4264_A4804 ENOG4108VDD TRNA binding domain protein BCB4264_A4810 ENOG4105C8F Beta-lactamase domain protein BCB4264_A4813 ENOG4108V15 phosphotransferase enzyme family BCB4264_A4814 ENOG4108IUM Glycogen debranching enzyme BCB4264_A4816 ENOG4107QSE Dipeptidase BCB4264_A4817 ENOG4105YW5 deoR family transcriptional regulator BCB4264_A4820 ENOG4105CBX hi0933 family BCB4264_A4827 ENOG4108VJ1 Transcriptional regulator (CarD family BCB4264_A4828 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCB4264_A4829 ENOG4105CSC Glucose uptake protein BCB4264_A4832 ENOG4108ZAF Molybdopterin BCB4264_A4833 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCB4264_A4834 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCB4264_A4836 ENOG4105D06 uba thif-type nad fad binding protein BCB4264_A4837 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCB4264_A4841 ENOG41085GJ domain protein BCB4264_A4843 ENOG4105DWV Homoserine O-trans-acetylase BCB4264_A4845 ENOG4108B31 Spore germination protein BCB4264_A4852 ENOG410605W Major Facilitator BCB4264_A4853 ENOG4107S91 Sodium hydrogen exchanger BCB4264_A4854 ENOG4105NCW Trka-c domain protein BCB4264_A4857 ENOG4105C19 ABC transporter BCB4264_A4861 ENOG4105N5T Radical SAM Protein BCB4264_A4863 ENOG4105CIG ABC transporter BCB4264_A4869 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCB4264_A4870 ENOG4108Z0R Transferase BCB4264_A4871 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCB4264_A4872 ENOG4105BZF Glycosyl transferase (Group 1 BCB4264_A4874 ENOG4105EPU Molybdenum cofactor synthesis domain protein BCB4264_A4893 ENOG4105BZU Histidine kinase BCB4264_A4894 ENOG4105BZU Histidine kinase BCB4264_A4895 ENOG4105CH6 catalase BCB4264_A4897 ENOG4107S9D Alpha beta hydrolase BCB4264_A4898 ENOG4107T7U Sulfatase BCB4264_A4901 ENOG4105D2X ABC transporter substrate-binding protein BCB4264_A4903 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCB4264_A4913 ENOG41080TC multidrug resistance protein BCB4264_A4914 ENOG4105KPY Small multidrug resistance protein BCB4264_A4919 ENOG4108V2W Carbonate dehydratase BCB4264_A4920 ENOG4105C4M (Ubiquinol oxidase) subunit I BCB4264_A4921 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCB4264_A4929 ENOG41087YS Phage shock protein A BCB4264_A4935 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BCB4264_A4936 ENOG4105BZU Histidine kinase BCB4264_A4937 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A4942 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCB4264_A4943 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCB4264_A4950 ENOG4105C19 ABC transporter BCB4264_A4953 ENOG4107ZTW SNARE associated Golgi BCB4264_A4956 ENOG4105C19 ABC transporter BCB4264_A4957 ENOG41086D8 Transcriptional regulator BCB4264_A4960 ENOG41082BM Transcriptional regulator, arsr family BCB4264_A4970 ENOG4105C6Z Gluconate BCB4264_A4971 ENOG4105FDP GntR family transcriptional regulator BCB4264_A4975 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCB4264_A4981 ENOG4105DTQ mandelate racemase muconate lactonizing BCB4264_A4982 ENOG4105CEY Amp-dependent synthetase and ligase BCB4264_A4984 ENOG4108IPT Naphthoate synthase BCB4264_A4985 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCB4264_A4986 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BCB4264_A4987 ENOG4105E4F Isochorismate synthase BCB4264_A4988 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCB4264_A4990 ENOG4105VEQ Cold shock protein BCB4264_A4998 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BCB4264_A5001 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCB4264_A5002 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCB4264_A5027 ENOG4105KT7 mgtC SapB transporter BCB4264_A5028 ENOG4107PBV potassium channel BCB4264_A5031 ENOG4105WG9 Conserved Protein BCB4264_A5033 ENOG4105CHM Aminotransferase BCB4264_A5034 ENOG4108ZB6 transcriptional regulator AsnC family BCB4264_A5035 ENOG4105C5I Dehydrogenase BCB4264_A5036 ENOG4108MUZ hydrolase BCB4264_A5038 ENOG4105C87 Aminotransferase class I and II BCB4264_A5041 ENOG4105Y38 Kinase-associated protein B BCB4264_A5043 ENOG4107R3E Citrate transporter BCB4264_A5046 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCB4264_A5047 ENOG4105KA0 thioesterase Superfamily protein BCB4264_A5050 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCB4264_A5055 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BCB4264_A5056 ENOG4106YN8 Prenyltransferase BCB4264_A5060 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BCB4264_A5061 ENOG4106YN8 Prenyltransferase BCB4264_A5062 ENOG41069ER domain protein BCB4264_A5065 ENOG4105CEP NADH dehydrogenase BCB4264_A5071 ENOG4105EWC Purine nucleoside phosphorylase BCB4264_A5075 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCB4264_A5080 ENOG4108JJA ABC, transporter BCB4264_A5081 ENOG4105C4B ABC transporter, permease BCB4264_A5082 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCB4264_A5092 ENOG41083MR nifu domain-containing protein BCB4264_A5095 ENOG4108W5N phosphatidylglycerophosphatase a BCB4264_A5099 ENOG4105DAX Pfam:DUF2983 BCB4264_A5101 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCB4264_A5102 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCB4264_A5105 ENOG4105CBT Fructose-1,6-bisphosphatase BCB4264_A5109 ENOG4105MMD transcriptional regulator BCB4264_A5110 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCB4264_A5111 ENOG4107TXC Transcriptional regulator BCB4264_A5112 ENOG41090T1 Membrane BCB4264_A5117 ENOG4105FAA peptidase M23 BCB4264_A5118 ENOG4108YTE sporulation protein YunB BCB4264_A5119 ENOG4105KZD Domain of unknown function (DUF1805) BCB4264_A5121 ENOG4105DIW FeS assembly protein SUFB BCB4264_A5122 ENOG4108UNV SUF system FeS assembly protein, NifU family BCB4264_A5123 ENOG4105C9B Cysteine desulfurase BCB4264_A5124 ENOG4105JRK feS assembly protein SufD BCB4264_A5125 ENOG4105C3K feS assembly ATPase SufC BCB4264_A5126 ENOG4105D01 (LipO)protein BCB4264_A5127 ENOG4105D01 (LipO)protein BCB4264_A5128 ENOG4108UMI ABC transporter, permease BCB4264_A5129 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCB4264_A5136 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCB4264_A5140 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCB4264_A5146 ENOG4108W8B Beta-lactamase domain protein BCB4264_A5147 ENOG4105C1G acyl-Coa dehydrogenase BCB4264_A5149 ENOG4105CHU acetyl-coa acetyltransferase BCB4264_A5152 ENOG4105DZ1 carboxypeptidase BCB4264_A5156 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCB4264_A5160 ENOG4108SUT Major Facilitator Superfamily BCB4264_A5161 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BCB4264_A5163 ENOG4107R7I amino acid BCB4264_A5166 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCB4264_A5168 ENOG4107AYK membrAne BCB4264_A5176 ENOG4107ZTW SNARE associated Golgi BCB4264_A5178 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCB4264_A5179 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A5180 ENOG4105BZU Histidine kinase BCB4264_A5186 ENOG4105C8Q Methyl-accepting chemotaxis BCB4264_A5187 ENOG4105VG1 fes assembly suf system protein BCB4264_A5188 ENOG4105D4Y metalloprotease BCB4264_A5192 ENOG4107T5V SNARE associated Golgi BCB4264_A5193 ENOG4107S91 Sodium hydrogen exchanger BCB4264_A5194 ENOG4105NCW Trka-c domain protein BCB4264_A5196 ENOG4108RMU ferritin dps family protein BCB4264_A5199 ENOG4108URH decarboxylase BCB4264_A5201 ENOG41090A1 ferritin BCB4264_A5203 ENOG4105D9N nucleoside BCB4264_A5204 ENOG4105D9N nucleoside BCB4264_A5207 ENOG4108RYK Nad-dependent epimerase dehydratase BCB4264_A5210 ENOG4105CV8 reductase BCB4264_A5211 ENOG4105F27 Major Facilitator BCB4264_A5212 ENOG4105KVH Transcriptional regulator BCB4264_A5215 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCB4264_A5216 ENOG4105D4A Cell wall formation (By similarity) BCB4264_A5220 ENOG4105WMR Protein CrcB homolog BCB4264_A5221 ENOG4105WMR Protein CrcB homolog BCB4264_A5224 ENOG4108MK9 spermidine N(1)-acetyltransferase BCB4264_A5225 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BCB4264_A5231 ENOG4108IPW abc transporter atp-binding protein BCB4264_A5232 ENOG4105CM4 permease protein BCB4264_A5238 ENOG4105D29 Helix-turn-helix type 11 domain protein BCB4264_A5243 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCB4264_A5245 ENOG4105XZU Preprotein translocase, subunit SecG BCB4264_A5246 ENOG41067MG lrgb family BCB4264_A5250 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BCB4264_A5256 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A5257 ENOG4105RHA ABC transporter, permease BCB4264_A5258 ENOG4108IUX (ABC) transporter BCB4264_A5260 ENOG4105BZU Histidine kinase BCB4264_A5261 ENOG4108W5X Transcriptional Regulator, LuxR family BCB4264_A5265 ENOG41090VF Stage v sporulation protein ac BCB4264_A5266 ENOG4105CZ3 stage V sporulation protein ad BCB4264_A5269 ENOG4108QY0 Membrane BCB4264_A5270 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCB4264_A5271 ENOG4105KRI phosphocarrier protein (HPr BCB4264_A5273 ENOG4105CHW UPF0052 protein BCB4264_A5274 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BCB4264_A5275 ENOG4108Z4K mutator MutT protein BCB4264_A5277 ENOG4105C3M thioredoxin reductase BCB4264_A5279 ENOG4108S4C acetyltransferase BCB4264_A5283 ENOG41086DT Membrane protein of unknown function BCB4264_A5285 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCB4264_A5286 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BCB4264_A5289 ENOG4107TXC Transcriptional regulator BCB4264_A5293 ENOG4105DUM transcriptional regulator, lysR family BCB4264_A5295 ENOG4108WS4 fmn reductase BCB4264_A5298 ENOG4105BZ1 (ABC) transporter BCB4264_A5300 ENOG4105CN1 protease BCB4264_A5301 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCB4264_A5302 ENOG4105CAK Cell division ATP-binding protein ftsE BCB4264_A5308 ENOG4105MS2 ribosomal subunit Interface protein BCB4264_A5310 ENOG4105VEQ Cold shock protein BCB4264_A5311 ENOG41081UC Inherit from COG: Competence protein BCB4264_A5315 ENOG4105KVH Transcriptional regulator BCB4264_A5318 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCB4264_A5319 ENOG4108KGH TRANSCRIPTIONal BCB4264_A5320 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCB4264_A5321 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCB4264_A5322 ENOG4105ESV Glycosyl transferase, family 4 BCB4264_A5324 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCB4264_A5328 ENOG4105F8D glycoside hydrolase family 4 BCB4264_A5329 ENOG4105VCP PTS System BCB4264_A5330 ENOG4105CK1 PTS System BCB4264_A5332 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BCB4264_A5333 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCB4264_A5334 ENOG4105VCP PTS System BCB4264_A5336 ENOG4105VZJ PTS System BCB4264_A5340 ENOG4105ECB domain protein BCB4264_A5341 ENOG4107RSM transcriptional regulator BCB4264_A5349 ENOG4105DAA L-lactate BCB4264_A5351 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCB4264_A5353 ENOG4105E0M Sulfatase BCB4264_A5361 ENOG4107R8N Glycosyl transferase, family 2 BCB4264_A5363 ENOG4105C94 Transporter BCB4264_A5364 ENOG41069ER domain protein BCB4264_A5369 ENOG4105KBK Zinc finger, swim domain protein BCB4264_A5370 ENOG4105C0D helicase BCB4264_A5376 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCB4264_A5378 ENOG4107RBB ABC transporter, permease BCB4264_A5379 ENOG4105C19 ABC transporter BCB4264_A5381 ENOG4105CXY transporter BCB4264_A5384 ENOG4105BZU Histidine kinase BCB4264_A5385 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A5387 ENOG4108KGH TRANSCRIPTIONal BCB4264_A5388 ENOG4105CMR udp-glucose 4-epimerase BCB4264_A5390 ENOG4108PQP glycosyl transferase group 1 BCB4264_A5392 ENOG4108KMV Glycosyl transferase (Group 1 BCB4264_A5395 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BCB4264_A5396 ENOG4107YJ4 chain length determinant protein BCB4264_A5397 ENOG4105HTX biosynthesis protein BCB4264_A5398 ENOG4107YJ4 chain length determinant protein BCB4264_A5401 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCB4264_A5403 ENOG4105FRN stage II sporulation protein BCB4264_A5406 ENOG4105DY9 regulatoR BCB4264_A5410 ENOG4106778 Protein of unknown function (DUF1146) BCB4264_A5411 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCB4264_A5412 ENOG4105C8S subunit m BCB4264_A5413 ENOG4105D65 subunit l BCB4264_A5418 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCB4264_A5419 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCB4264_A5421 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCB4264_A5422 ENOG4105BZU Histidine kinase BCB4264_A5433 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCB4264_A5434 ENOG41062M3 atp synthase BCB4264_A5439 ENOG4108UIC UPF0340 protein BCB4264_A5440 ENOG4108YZG isomerase BCB4264_A5443 ENOG4108VGI doxx family BCB4264_A5444 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCB4264_A5448 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCB4264_A5450 ENOG4108ZXQ stage ii sporulation protein r BCB4264_A5451 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCB4264_A5452 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCB4264_A5455 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCB4264_A5456 ENOG4105CBT Fructose-1,6-bisphosphatase BCB4264_A5457 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCB4264_A5464 ENOG4105C1G acyl-Coa dehydrogenase BCB4264_A5465 ENOG4105C1G acyl-Coa dehydrogenase BCB4264_A5466 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCB4264_A5468 ENOG4105DF6 Fe-S oxidoreductase BCB4264_A5471 ENOG4105BZU Histidine kinase BCB4264_A5474 ENOG4105D4Y metalloprotease BCB4264_A5476 ENOG4105BZU Histidine kinase BCB4264_A5477 ENOG4105KCT ABC transporter BCB4264_A5478 ENOG4108M15 ABC transporter BCB4264_A5479 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCB4264_A5481 ENOG4105IIU Aminopeptidase BCB4264_A5484 ENOG4105DU6 RNA polymerase BCB4264_A5486 ENOG410684U Domain of unknown function (DUF1934) BCB4264_A5491 ENOG4105CYW agmatinase BCB4264_A5493 ENOG4105DXB Major Facilitator superfamily BCB4264_A5494 ENOG4107SWG transcriptional regulator MERR family BCB4264_A5496 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCB4264_A5497 ENOG4105BZ4 penicillin-binding protein BCB4264_A5498 ENOG4108XFG YwhD family BCB4264_A5499 ENOG4108Z4T Peptidase M50 BCB4264_A5500 ENOG41069HH 4-oxalocrotonate tautomerase BCB4264_A5502 ENOG4105DCI Phosphohydrolase BCB4264_A5503 ENOG4108MES Periplasmic binding protein BCB4264_A5504 ENOG4105E0A ABC, transporter BCB4264_A5505 ENOG4105EHG Permease protein BCB4264_A5506 ENOG4105DQ5 transport system permease protein BCB4264_A5508 ENOG4108VCI transcription factor, rsfa family BCB4264_A5509 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BCB4264_A5510 ENOG4108IJ2 phosphate acetyltransferase BCB4264_A5511 ENOG4107UEZ chlorite dismutase BCB4264_A5513 ENOG4108VKI Cell wall hydrolase BCB4264_A5517 ENOG4107SVH Potassium channel protein BCB4264_A5519 ENOG410667J hydrolase BCB4264_A5520 ENOG4105VCH membrane BCB4264_A5522 ENOG4108TU7 Inherit from COG: (ABC) transporter BCB4264_A5523 ENOG4105CJ1 ABC, transporter BCB4264_A5524 ENOG41090WU lipolytic protein G-D-S-L family BCB4264_A5527 ENOG4105D6E homoserine dehydrogenase BCB4264_A5533 ENOG4108Y4K DNA-binding transcriptional activator BCB4264_A5535 ENOG4105WH1 Two component transcriptional regulator luxr family BCB4264_A5536 ENOG4105BZU Histidine kinase BCB4264_A5537 ENOG4105DWF phosphomethylpyrimidine kinase BCB4264_A5538 ENOG4105BZU Histidine kinase BCB4264_A5539 ENOG4105VCD cytoplasmic protein BCB4264_A5540 ENOG4105D22 carbon starvation protein BCB4264_A5541 ENOG4105DY9 regulatoR BCB4264_A5543 ENOG41079KZ Major Facilitator Superfamily BCB4264_A5545 ENOG4105CG5 Glycosyl transferase (Group 1 BCB4264_A5547 ENOG4105EN6 Membrane BCB4264_A5548 ENOG4106YBV Methyl-accepting chemotaxis BCB4264_A5550 ENOG4108S4H thioesterase Superfamily protein BCB4264_A5552 ENOG4105K64 Glycosyl transferase, family 2 BCB4264_A5555 ENOG4105CKK Glycosyl transferase, family 2 BCB4264_A5556 ENOG4105C5H ABC transporter BCB4264_A5557 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCB4264_A5559 ENOG41067SE Tetr family transcriptional regulator BCB4264_A5561 ENOG4105E0X reductase BCB4264_A5562 ENOG4106F5Q Membrane BCB4264_A5565 ENOG4108NEV two component transcriptional regulator, LytTR family BCB4264_A5566 ENOG4108HRK Histidine kinase BCB4264_A5568 ENOG4107RGD Major Facilitator superfamily BCB4264_A5571 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCB4264_A5573 ENOG4105IW1 AmiS UreI transporter BCB4264_A5574 ENOG4105CMR udp-glucose 4-epimerase BCB4264_A5575 ENOG4108UT2 hemolysin iii BCB4264_A5577 ENOG4105C1J atp-dependent rna helicase BCB4264_A5578 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BCB4264_A5579 ENOG4105DPN Oligoendopeptidase f BCB4264_A5581 ENOG4105BZU Histidine kinase BCB4264_A5584 ENOG4105C0H protease BCB4264_A5585 ENOG4105Q2H domain protein BCB4264_A5588 ENOG4105BZU Histidine kinase BCB4264_A5589 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCB4264_A5594 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BCB4264_A5595 ENOG4105CDU Replicative dna helicase BCB4264_A5597 ENOG4105BZR domain protein BCB4264_A5598 ENOG4108XMW Membrane BCB4264_A5600 ENOG4108UUM single-stranded DNA-binding protein BCB4264_A5602 ENOG4105C3G gtp-binding protein BCB4264_A5603 ENOG4105VDK protein, conserved in bacteria BCB4264_A5604 ENOG4105D8X mechanosensitive ion channel BCB4264_A5605 ENOG4108ZDA Sporulation protein YyaC BCB4264_A5606 ENOG4105FA0 parb-like partition protein BCB4264_A5607 ENOG4107QJE Chromosome Partitioning Protein BCB4264_A5610 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BCB4264_A5611 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BCB4264_A5613 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins