locus-tag	class	description
J8Y18_00010	COG0592	DNA-directed DNA polymerase activity
J8Y18_00015	COG2501	S4 domain
J8Y18_00025	COG0187	DNA topoisomerase II activity
J8Y18_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J8Y18_00065	COG0516	GMP reductase activity
J8Y18_00065	COG0517	IMP dehydrogenase activity
J8Y18_00070	COG1686	Belongs to the peptidase S11 family
J8Y18_00100	COG1428	Deoxynucleoside kinase
J8Y18_00105	COG1428	Deoxynucleoside kinase
J8Y18_00110	COG1335	isochorismatase
J8Y18_00115	COG0590	tRNA wobble adenosine to inosine editing
J8Y18_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J8Y18_00180	COG1982	Orn Lys Arg decarboxylase major
J8Y18_00190	COG0470	DNA polymerase III
J8Y18_00195	COG1774	PSP1 C-terminal conserved region
J8Y18_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J8Y18_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J8Y18_00220	COG2002	toxin-antitoxin pair type II binding
J8Y18_00230	COG0084	hydrolase, TatD family'
J8Y18_00250	COG4466	Protein conserved in bacteria
J8Y18_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J8Y18_00270	COG0251	oxidation-reduction process
J8Y18_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J8Y18_00305	COG2002	toxin-antitoxin pair type II binding
J8Y18_00310	COG2244	polysaccharide biosynthetic process
J8Y18_00315	COG3956	TIGRFAM MazG family protein
J8Y18_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J8Y18_00340	COG1098	S1 RNA binding domain
J8Y18_00355	COG2208	phosphoserine phosphatase activity
J8Y18_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J8Y18_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J8Y18_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y18_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J8Y18_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Y18_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y18_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J8Y18_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J8Y18_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J8Y18_00420	COG1396	sequence-specific DNA binding
J8Y18_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Y18_00515	COG3880	PFAM UvrB UvrC protein
J8Y18_00525	COG0542	response to heat
J8Y18_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J8Y18_00540	COG4956	integral membrane protein (PIN domain superfamily)
J8Y18_00560	COG1045	serine acetyltransferase
J8Y18_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Y18_00580	COG3688	RNA-binding protein containing a PIN domain
J8Y18_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Y18_00600	COG0250	Participates in transcription elongation, termination and antitermination
J8Y18_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J8Y18_00625	COG2813	Specifically methylates the guanine in position
J8Y18_00640	COG1358	cellular component organization or biogenesis
J8Y18_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J8Y18_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
J8Y18_00770	COG0201	protein transport
J8Y18_00780	COG0024	Methionine aminopeptidase
J8Y18_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J8Y18_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J8Y18_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y18_00855	COG0489	protein tyrosine kinase activity
J8Y18_00865	COG2194	sulfuric ester hydrolase activity
J8Y18_00870	COG0726	polysaccharide deacetylase
J8Y18_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J8Y18_00955	COG4856	YbbR-like protein
J8Y18_01005	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_01010	COG2011	ABC-type metal ion transport system permease component
J8Y18_01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J8Y18_01020	COG1464	Belongs to the NlpA lipoprotein family
J8Y18_01025	COG0604	alcohol dehydrogenase
J8Y18_01035	COG0277	FAD linked oxidase domain protein
J8Y18_01040	COG2271	Major facilitator Superfamily
J8Y18_01050	COG2814	Major facilitator Superfamily
J8Y18_01070	COG2207	Transcriptional regulator
J8Y18_01085	COG4166	transmembrane transport
J8Y18_01090	COG4166	transmembrane transport
J8Y18_01095	COG0656	L-ascorbic acid biosynthetic process
J8Y18_01115	COG4149	molybdate abc transporter
J8Y18_01120	COG0725	ABC transporter, periplasmic molybdate-binding protein
J8Y18_01125	COG1910	domain protein
J8Y18_01140	COG0697	spore germination
J8Y18_01155	COG0204	Acyl-transferase
J8Y18_01165	COG1609	Transcriptional regulator
J8Y18_01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_01190	COG5298	Protein conserved in bacteria
J8Y18_01210	COG0488	(ABC) transporter
J8Y18_01220	COG0747	negative chemotaxis
J8Y18_01225	COG0601	transmembrane transport
J8Y18_01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y18_01235	COG0444	Belongs to the ABC transporter superfamily
J8Y18_01240	COG4608	Belongs to the ABC transporter superfamily
J8Y18_01245	COG0561	phosphatase activity
J8Y18_01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J8Y18_01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
J8Y18_01290	COG0531	amino acid
J8Y18_01295	COG2814	Major facilitator Superfamily
J8Y18_01305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J8Y18_01315	COG4294	response to UV
J8Y18_01320	COG0705	Rhomboid family
J8Y18_01330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J8Y18_01335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Y18_01340	COG0864	Transcriptional regulator
J8Y18_01345	COG2337	Toxic component of a toxin-antitoxin (TA) module
J8Y18_01350	COG2183	response to ionizing radiation
J8Y18_01450	COG0802	atpase or kinase
J8Y18_01455	COG1214	PFAM Peptidase M22, glycoprotease
J8Y18_01460	COG0456	acetyltransferase
J8Y18_01470	COG0488	(ABC) transporter
J8Y18_01485	COG1266	CAAX protease self-immunity
J8Y18_01505	COG2252	PERMEase
J8Y18_01515	COG5002	protein histidine kinase activity
J8Y18_01540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J8Y18_01580	COG2205	protein histidine kinase activity
J8Y18_01585	COG0745	RESPONSE REGULATOR receiver
J8Y18_01615	COG2226	methyltransferase
J8Y18_01625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y18_01635	COG1215	transferase activity, transferring glycosyl groups
J8Y18_01655	COG0697	spore germination
J8Y18_01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J8Y18_01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J8Y18_01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J8Y18_01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J8Y18_01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J8Y18_01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J8Y18_01735	COG0151	Belongs to the GarS family
J8Y18_01760	COG0210	DNA helicase
J8Y18_01770	COG4851	CamS sex pheromone cAM373 precursor
J8Y18_01785	COG1335	isochorismatase
J8Y18_01795	COG2011	ABC-type metal ion transport system permease component
J8Y18_01800	COG1464	Belongs to the NlpA lipoprotein family
J8Y18_01815	COG0003	Pfam Anion-transporting ATPase
J8Y18_01820	COG1846	Transcriptional regulator
J8Y18_01825	COG4682	membrane
J8Y18_01845	COG1597	lipid kinase activity
J8Y18_01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J8Y18_01865	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_01870	COG2076	Multidrug Resistance protein
J8Y18_01880	COG2309	aminopeptidase activity
J8Y18_01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Y18_01915	COG4807	Protein conserved in bacteria
J8Y18_01940	COG1757	Na H antiporter
J8Y18_01945	COG1473	amidohydrolase
J8Y18_01965	COG0450	alkyl hydroperoxide reductase
J8Y18_01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_02000	COG0492	ferredoxin-NADP+ reductase activity
J8Y18_02010	COG0166	Belongs to the GPI family
J8Y18_02035	COG5002	protein histidine kinase activity
J8Y18_02055	COG3541	Predicted nucleotidyltransferase
J8Y18_02060	COG2814	Major facilitator Superfamily
J8Y18_02065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y18_02065	COG0723	plastoquinol--plastocyanin reductase activity
J8Y18_02075	COG0765	amino acid transport
J8Y18_02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y18_02085	COG1126	abc transporter atp-binding protein
J8Y18_02090	COG0840	transmembrane signaling receptor activity
J8Y18_02115	COG0549	Belongs to the carbamate kinase family
J8Y18_02120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Y18_02130	COG0277	FAD linked oxidase domain protein
J8Y18_02135	COG0366	Alpha amylase catalytic
J8Y18_02140	COG2190	(PTS) system
J8Y18_02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_02140	COG1263	PTS System
J8Y18_02170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J8Y18_02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y18_02195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y18_02200	COG1116	anion transmembrane transporter activity
J8Y18_02205	COG0488	(ABC) transporter
J8Y18_02250	COG2270	Major facilitator Superfamily
J8Y18_02280	COG2310	stress, protein
J8Y18_02285	COG2310	stress, protein
J8Y18_02290	COG2310	stress, protein
J8Y18_02295	COG0861	Integral membrane protein TerC family
J8Y18_02305	COG3853	Toxic anion resistance protein (TelA)
J8Y18_02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8Y18_02330	COG1295	ribonuclease BN
J8Y18_02335	COG2217	Heavy metal translocating P-type atpase
J8Y18_02340	COG0697	spore germination
J8Y18_02350	COG0681	Belongs to the peptidase S26 family
J8Y18_02360	COG0586	Pfam SNARE associated Golgi protein
J8Y18_02375	COG3871	stress protein (general stress protein 26)
J8Y18_02380	COG0387	Pfam Sodium calcium exchanger
J8Y18_02390	COG0535	radical SAM domain protein
J8Y18_02410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J8Y18_02415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J8Y18_02430	COG3829	transcription factor binding
J8Y18_02440	COG0833	amino acid
J8Y18_02445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y18_02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_02475	COG1263	PTS System
J8Y18_02480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y18_02495	COG0463	Glycosyl transferase, family 2
J8Y18_02505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y18_02505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J8Y18_02525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J8Y18_02545	COG1228	amidohydrolase
J8Y18_02550	COG1090	epimerase
J8Y18_02580	COG1988	membrane-bound metal-dependent
J8Y18_02585	COG1194	a g-specific adenine glycosylase
J8Y18_02610	COG1132	(ABC) transporter
J8Y18_02615	COG4129	membrane
J8Y18_02620	COG0067	glutamate synthase
J8Y18_02620	COG0069	glutamate synthase activity
J8Y18_02620	COG0070	glutamate synthase
J8Y18_02630	COG4555	ABC transporter
J8Y18_02650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J8Y18_02655	COG0735	belongs to the Fur family
J8Y18_02775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J8Y18_02800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J8Y18_02810	COG2766	serine protein kinase
J8Y18_02830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y18_02840	COG1585	Membrane protein implicated in regulation of membrane protease activity
J8Y18_02845	COG2268	Band 7 protein
J8Y18_02855	COG3290	protein histidine kinase activity
J8Y18_02860	COG4565	transcriptional regulatory protein
J8Y18_02865	COG2851	Citrate transporter
J8Y18_02890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J8Y18_02895	COG3842	ATPase activity
J8Y18_02900	COG1175	transmembrane transport
J8Y18_02905	COG0395	ABC-type sugar transport system, permease component
J8Y18_02915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J8Y18_02920	COG0745	RESPONSE REGULATOR receiver
J8Y18_02925	COG5002	protein histidine kinase activity
J8Y18_02935	COG4990	cell redox homeostasis
J8Y18_02945	COG3290	protein histidine kinase activity
J8Y18_02950	COG4565	transcriptional regulatory protein
J8Y18_02955	COG3493	citrate carrier protein
J8Y18_02960	COG0281	malic enzyme
J8Y18_02970	COG0697	spore germination
J8Y18_02975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_02985	COG5002	protein histidine kinase activity
J8Y18_03000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J8Y18_03005	COG3383	formate dehydrogenase (NAD+) activity
J8Y18_03010	COG2427	Protein of unknown function (DUF1641)
J8Y18_03025	COG0531	amino acid
J8Y18_03035	COG0640	Transcriptional regulator
J8Y18_03040	COG2217	Heavy metal translocating P-type atpase
J8Y18_03045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J8Y18_03060	COG3227	Zinc metalloprotease (Elastase)
J8Y18_03080	COG2720	vancomycin resistance protein
J8Y18_03085	COG1316	TRANSCRIPTIONal
J8Y18_03090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_03095	COG0346	lactoylglutathione lyase activity
J8Y18_03100	COG1253	flavin adenine dinucleotide binding
J8Y18_03105	COG1027	Aspartate ammonia-lyase
J8Y18_03110	COG1620	l-lactate permease
J8Y18_03125	COG3104	oligopeptide transport
J8Y18_03130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_03160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y18_03170	COG4548	von Willebrand factor, type A
J8Y18_03175	COG0714	Associated with various cellular activities
J8Y18_03195	COG0531	amino acid
J8Y18_03200	COG2188	Transcriptional regulator
J8Y18_03205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_03205	COG1263	PTS System
J8Y18_03210	COG0366	Alpha amylase catalytic
J8Y18_03225	COG0697	spore germination
J8Y18_03230	COG4585	Histidine kinase
J8Y18_03235	COG2197	response regulator
J8Y18_03240	COG1404	Belongs to the peptidase S8 family
J8Y18_03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8Y18_03255	COG1115	amino acid carrier protein
J8Y18_03260	COG1126	abc transporter atp-binding protein
J8Y18_03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y18_03270	COG0765	amino acid transport
J8Y18_03275	COG0765	amino acid transport
J8Y18_03280	COG0833	amino acid
J8Y18_03305	COG2378	regulation of single-species biofilm formation
J8Y18_03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J8Y18_03315	COG5002	protein histidine kinase activity
J8Y18_03330	COG0659	secondary active sulfate transmembrane transporter activity
J8Y18_03345	COG2271	Major facilitator Superfamily
J8Y18_03350	COG1846	Transcriptional regulator
J8Y18_03355	COG0477	Major facilitator Superfamily
J8Y18_03360	COG1609	Transcriptional regulator
J8Y18_03365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Y18_03380	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Y18_03385	COG1879	ABC-type sugar transport system periplasmic component
J8Y18_03405	COG1063	alcohol dehydrogenase
J8Y18_03455	COG0840	transmembrane signaling receptor activity
J8Y18_03460	COG1388	LysM domain
J8Y18_03460	COG3584	3D domain protein
J8Y18_03465	COG1476	TRANSCRIPTIONal
J8Y18_03485	COG3104	oligopeptide transport
J8Y18_03490	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_03505	COG1113	amino acid transport
J8Y18_03510	COG2252	PERMEase
J8Y18_03535	COG2153	protein acetylation
J8Y18_03545	COG0569	domain protein
J8Y18_03545	COG0475	glutathione-regulated potassium exporter activity
J8Y18_03560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J8Y18_03570	COG0833	amino acid
J8Y18_03575	COG4990	cell redox homeostasis
J8Y18_03590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y18_03595	COG0697	spore germination
J8Y18_03600	COG0531	amino acid
J8Y18_03615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y18_03620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y18_03625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y18_03625	COG1918	ferrous iron import across plasma membrane
J8Y18_03630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8Y18_03635	COG0573	inorganic phosphate transmembrane transporter activity
J8Y18_03640	COG0581	inorganic phosphate transmembrane transporter activity
J8Y18_03650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Y18_03770	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J8Y18_03790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J8Y18_03795	COG1116	anion transmembrane transporter activity
J8Y18_03800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y18_03805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y18_03810	COG0352	thiamine-phosphate diphosphorylase activity
J8Y18_03815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y18_03820	COG2104	thiamine diphosphate biosynthetic process
J8Y18_03830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y18_03835	COG0351	phosphomethylpyrimidine kinase
J8Y18_03875	COG2205	protein histidine kinase activity
J8Y18_03880	COG2814	Major facilitator Superfamily
J8Y18_03885	COG1846	Transcriptional regulator
J8Y18_03895	COG2252	PERMEase
J8Y18_03900	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_03915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Y18_03920	COG1621	beta-fructofuranosidase activity
J8Y18_03925	COG1263	PTS System
J8Y18_03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_03930	COG1609	Transcriptional regulator
J8Y18_03980	COG0778	Nitroreductase
J8Y18_03985	COG2719	SpoVR family
J8Y18_03995	COG1414	Transcriptional regulator
J8Y18_04010	COG0446	pyridine nucleotide-disulphide oxidoreductase
J8Y18_04015	COG1937	Protein conserved in bacteria
J8Y18_04020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_04020	COG0425	Belongs to the sulfur carrier protein TusA family
J8Y18_04025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_04030	COG0425	Belongs to the sulfur carrier protein TusA family
J8Y18_04035	COG0425	Belongs to the sulfur carrier protein TusA family
J8Y18_04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_04045	COG2210	Belongs to the sulfur carrier protein TusA family
J8Y18_04050	COG0730	response to heat
J8Y18_04060	COG1316	TRANSCRIPTIONal
J8Y18_04065	COG0604	alcohol dehydrogenase
J8Y18_04070	COG1283	sodium-dependent phosphate transmembrane transporter activity
J8Y18_04085	COG3711	transcriptional antiterminator
J8Y18_04085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y18_04090	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y18_04095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y18_04120	COG3584	3D domain protein
J8Y18_04120	COG1388	LysM domain
J8Y18_04125	COG0577	efflux transmembrane transporter activity
J8Y18_04130	COG1136	(ABC) transporter
J8Y18_04140	COG5522	Integral membrane protein (intg_mem_TP0381)
J8Y18_04155	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_04160	COG3546	catalase activity
J8Y18_04195	COG0586	Pfam SNARE associated Golgi protein
J8Y18_04230	COG0531	amino acid
J8Y18_04235	COG0475	glutathione-regulated potassium exporter activity
J8Y18_04245	COG1737	Transcriptional regulator
J8Y18_04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_04255	COG1263	PTS System
J8Y18_04265	COG2259	Doxx family
J8Y18_04285	COG1522	sequence-specific DNA binding
J8Y18_04290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J8Y18_04290	COG0165	Argininosuccinate lyase
J8Y18_04295	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_04315	COG1309	transcriptional regulator
J8Y18_04320	COG2814	Major facilitator Superfamily
J8Y18_04325	COG1733	regulation of RNA biosynthetic process
J8Y18_04335	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y18_04345	COG4533	DNA binding
J8Y18_04350	COG2211	Major facilitator Superfamily
J8Y18_04365	COG0693	protein deglycase activity
J8Y18_04370	COG4473	ABC transporter
J8Y18_04375	COG0531	amino acid
J8Y18_04390	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_04395	COG1132	(ABC) transporter
J8Y18_04400	COG1132	(ABC) transporter
J8Y18_04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y18_04410	COG0765	amino acid transport
J8Y18_04415	COG1126	abc transporter atp-binding protein
J8Y18_04430	COG0189	ligase activity
J8Y18_04460	COG0028	Belongs to the TPP enzyme family
J8Y18_04465	COG3527	Alpha-acetolactate decarboxylase
J8Y18_04475	COG0561	phosphatase activity
J8Y18_04485	COG3409	Peptidoglycan-binding domain 1 protein
J8Y18_04485	COG5632	N-Acetylmuramoyl-L-alanine amidase
J8Y18_04490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Y18_04495	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_04510	COG0659	secondary active sulfate transmembrane transporter activity
J8Y18_04515	COG2244	polysaccharide biosynthetic process
J8Y18_04535	COG1024	Enoyl-CoA hydratase
J8Y18_04555	COG1363	Peptidase, m42
J8Y18_04590	COG0601	transmembrane transport
J8Y18_04595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y18_04600	COG0444	Belongs to the ABC transporter superfamily
J8Y18_04605	COG4608	Belongs to the ABC transporter superfamily
J8Y18_04630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_04650	COG0457	Tetratricopeptide repeat
J8Y18_04770	COG0477	Major facilitator Superfamily
J8Y18_04775	COG3290	protein histidine kinase activity
J8Y18_04780	COG4565	transcriptional regulatory protein
J8Y18_04785	COG3181	Tripartite tricarboxylate transporter family receptor
J8Y18_04830	COG0305	Participates in initiation and elongation during chromosome replication
J8Y18_04860	COG0477	Major facilitator Superfamily
J8Y18_04875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_04905	COG1073	alpha beta
J8Y18_04945	COG1183	phosphatidylcholine synthase activity
J8Y18_04960	COG2376	Dihydroxyacetone kinase
J8Y18_04970	COG2376	Dihydroxyacetone kinase
J8Y18_05005	COG1388	LysM domain
J8Y18_05005	COG3584	3D domain protein
J8Y18_05010	COG0791	NLP P60 protein
J8Y18_05010	COG1388	LysM domain
J8Y18_05015	COG2373	Large extracellular alpha-helical protein
J8Y18_05035	COG0596	Alpha beta hydrolase
J8Y18_05080	COG3237	CsbD-like
J8Y18_05105	COG1191	sigma factor activity
J8Y18_05115	COG2208	phosphoserine phosphatase activity
J8Y18_05120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Y18_05125	COG5002	protein histidine kinase activity
J8Y18_05125	COG2205	protein histidine kinase activity
J8Y18_05125	COG0784	Response regulator, receiver
J8Y18_05170	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J8Y18_05190	COG0420	3'-5' exonuclease activity
J8Y18_05195	COG4717	serine-type aminopeptidase activity
J8Y18_05205	COG0346	lactoylglutathione lyase activity
J8Y18_05210	COG0346	lactoylglutathione lyase activity
J8Y18_05215	COG0457	Tetratricopeptide repeat
J8Y18_05225	COG2267	carboxylic ester hydrolase activity
J8Y18_05250	COG2140	Oxalate decarboxylase
J8Y18_05255	COG3620	sequence-specific DNA binding
J8Y18_05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J8Y18_05265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J8Y18_05275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J8Y18_05335	COG1136	(ABC) transporter
J8Y18_05345	COG1695	Transcriptional regulator
J8Y18_05380	COG3973	AAA domain
J8Y18_05410	COG4980	gas vesicle protein
J8Y18_05415	COG0537	adenosine 5'-monophosphoramidase activity
J8Y18_05420	COG1131	(ABC) transporter
J8Y18_05425	COG4473	ABC transporter
J8Y18_05450	COG3402	PFAM membrane-flanked domain
J8Y18_05455	COG3428	Bacterial PH domain
J8Y18_05490	COG0697	spore germination
J8Y18_05495	COG3402	PFAM membrane-flanked domain
J8Y18_05500	COG3428	Bacterial PH domain
J8Y18_05505	COG2329	Antibiotic biosynthesis monooxygenase
J8Y18_05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y18_05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J8Y18_05560	COG1309	transcriptional regulator
J8Y18_05565	COG1511	domain protein
J8Y18_05580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_05585	COG1609	Transcriptional regulator
J8Y18_05595	COG1234	tRNA 3'-trailer cleavage
J8Y18_05600	COG0095	Lipoate-protein ligase
J8Y18_05610	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_05620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J8Y18_05630	COG4208	sulfate ABC transporter
J8Y18_05715	COG1073	alpha beta
J8Y18_05720	COG1408	metallophosphoesterase
J8Y18_05725	COG1078	dGTPase activity
J8Y18_05735	COG1595	DNA-templated transcription, initiation
J8Y18_05740	COG2207	Transcriptional regulator
J8Y18_05740	COG3708	Transcriptional regulator
J8Y18_05755	COG2205	protein histidine kinase activity
J8Y18_05760	COG0745	RESPONSE REGULATOR receiver
J8Y18_05780	COG0501	Belongs to the peptidase M48B family
J8Y18_05785	COG0840	transmembrane signaling receptor activity
J8Y18_05790	COG3693	PFAM glycoside hydrolase, family 10
J8Y18_05800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J8Y18_05805	COG2224	Isocitrate lyase
J8Y18_05845	COG0398	Pfam SNARE associated Golgi protein
J8Y18_05905	COG0179	Fumarylacetoacetate (FAA) hydrolase
J8Y18_05930	COG0367	asparagine synthase
J8Y18_05940	COG0753	catalase activity
J8Y18_05945	COG0004	ammonium transporteR
J8Y18_05965	COG2996	Protein conserved in bacteria
J8Y18_05990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_06005	COG0561	phosphatase activity
J8Y18_06025	COG2267	carboxylic ester hydrolase activity
J8Y18_06045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J8Y18_06050	COG5504	Zn-dependent protease
J8Y18_06065	COG0180	Tryptophanyl-tRNA synthetase
J8Y18_06075	COG4166	transmembrane transport
J8Y18_06080	COG0601	transmembrane transport
J8Y18_06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y18_06090	COG0444	Belongs to the ABC transporter superfamily
J8Y18_06095	COG4608	Belongs to the ABC transporter superfamily
J8Y18_06100	COG0534	Mate efflux family protein
J8Y18_06105	COG4166	transmembrane transport
J8Y18_06120	COG0861	Integral membrane protein TerC family
J8Y18_06140	COG1164	Oligoendopeptidase f
J8Y18_06155	COG2346	COG2346, Truncated hemoglobins
J8Y18_06160	COG4116	CYTH
J8Y18_06170	COG2357	RelA SpoT domain protein
J8Y18_06180	COG0564	pseudouridine synthase activity
J8Y18_06195	COG0772	Belongs to the SEDS family
J8Y18_06200	COG1216	Glycosyl transferase, family 2
J8Y18_06220	COG0457	Tetratricopeptide repeat
J8Y18_06220	COG0463	Glycosyl transferase, family 2
J8Y18_06240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J8Y18_06255	COG1091	dTDP-4-dehydrorhamnose reductase activity
J8Y18_06300	COG2153	protein acetylation
J8Y18_06310	COG2382	esterase
J8Y18_06330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y18_06340	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Y18_06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8Y18_06375	COG1620	l-lactate permease
J8Y18_06380	COG5634	Uncharacterized conserved protein (DUF2278)
J8Y18_06435	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y18_06490	COG1686	Belongs to the peptidase S11 family
J8Y18_06495	COG0681	Belongs to the peptidase S26 family
J8Y18_06530	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_06540	COG1176	ABC-type spermidine putrescine transport system, permease component I
J8Y18_06545	COG1177	transmembrane transport
J8Y18_06560	COG2409	Drug exporters of the RND superfamily
J8Y18_06570	COG0564	pseudouridine synthase activity
J8Y18_06580	COG2340	Cysteine-rich secretory protein family
J8Y18_06585	COG0247	lactate metabolic process
J8Y18_06590	COG0277	FAD linked oxidase domain protein
J8Y18_06595	COG3835	regulator
J8Y18_06605	COG0745	RESPONSE REGULATOR receiver
J8Y18_06610	COG5002	protein histidine kinase activity
J8Y18_06615	COG2186	Transcriptional regulator
J8Y18_06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J8Y18_06645	COG2116	formate transmembrane transporter activity
J8Y18_06650	COG0861	Integral membrane protein TerC family
J8Y18_06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y18_06665	COG2030	dehydratase
J8Y18_06685	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_06690	COG3243	poly(R)-hydroxyalkanoic acid synthase
J8Y18_06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y18_06715	COG1840	ABC-type Fe3 transport system, periplasmic component
J8Y18_06720	COG3842	ATPase activity
J8Y18_06745	COG1349	DNA-binding transcription factor activity
J8Y18_06755	COG0235	Class ii aldolase
J8Y18_06765	COG2861	carbohydrate metabolic process
J8Y18_06775	COG3852	Histidine kinase
J8Y18_06780	COG1846	Transcriptional regulator
J8Y18_06790	COG2318	DinB family
J8Y18_06795	COG5002	protein histidine kinase activity
J8Y18_06805	COG0720	synthase
J8Y18_06820	COG4873	Protein conserved in bacteria
J8Y18_06850	COG1780	Probably involved in ribonucleotide reductase function
J8Y18_06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J8Y18_06880	COG1725	Transcriptional regulator
J8Y18_06885	COG1131	(ABC) transporter
J8Y18_06895	COG1131	(ABC) transporter
J8Y18_06905	COG1266	CAAX protease self-immunity
J8Y18_06915	COG1522	sequence-specific DNA binding
J8Y18_06925	COG1335	isochorismatase
J8Y18_06935	COG1619	proteins homologs of microcin C7 resistance protein MccF
J8Y18_06940	COG2070	2-Nitropropane dioxygenase
J8Y18_06945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J8Y18_06955	COG1696	Membrane protein involved in D-alanine export
J8Y18_06980	COG0716	FMN binding
J8Y18_06995	COG3173	Aminoglycoside phosphotransferase
J8Y18_07035	COG1846	Transcriptional regulator
J8Y18_07045	COG1301	dicarboxylic acid transport
J8Y18_07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y18_07055	COG4709	membrane
J8Y18_07060	COG3874	Sporulation protein YtfJ
J8Y18_07080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y18_07085	COG0028	Belongs to the TPP enzyme family
J8Y18_07090	COG0440	acetolactate synthase activity
J8Y18_07165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Y18_07180	COG1183	phosphatidylcholine synthase activity
J8Y18_07185	COG1368	sulfuric ester hydrolase activity
J8Y18_07195	COG0019	diaminopimelate decarboxylase activity
J8Y18_07215	COG0529	Catalyzes the synthesis of activated sulfate
J8Y18_07220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Y18_07240	COG1648	precorrin-2 dehydrogenase activity
J8Y18_07245	COG0733	neurotransmitter:sodium symporter activity
J8Y18_07270	COG1757	Na H antiporter
J8Y18_07285	COG4758	membrane
J8Y18_07290	COG4585	Histidine kinase
J8Y18_07295	COG2197	response regulator
J8Y18_07305	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_07355	COG0730	response to heat
J8Y18_07360	COG0306	phosphate transporter
J8Y18_07365	COG1392	Phosphate transport regulator
J8Y18_07370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y18_07385	COG3852	Histidine kinase
J8Y18_07390	COG1801	Protein of unknown function DUF72
J8Y18_07400	COG0582	viral genome integration into host DNA
J8Y18_07405	COG5002	protein histidine kinase activity
J8Y18_07420	COG0392	lysyltransferase activity
J8Y18_07420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J8Y18_07435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Y18_07440	COG1686	Belongs to the peptidase S11 family
J8Y18_07445	COG2715	membrane protein required for spore maturation
J8Y18_07450	COG0700	Nucleoside recognition
J8Y18_07455	COG1187	pseudouridine synthase activity
J8Y18_07465	COG1333	cytochrome c biogenesis protein
J8Y18_07470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Y18_07475	COG0745	RESPONSE REGULATOR receiver
J8Y18_07480	COG5002	protein histidine kinase activity
J8Y18_07485	COG2096	Adenosyltransferase
J8Y18_07500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J8Y18_07505	COG1141	Ferredoxin
J8Y18_07515	COG0514	ATP-dependent DNA helicase (RecQ)
J8Y18_07520	COG1266	CAAX protease self-immunity
J8Y18_07530	COG1408	metallophosphoesterase
J8Y18_07535	COG0789	Transcriptional regulator
J8Y18_07545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J8Y18_07565	COG0492	ferredoxin-NADP+ reductase activity
J8Y18_07570	COG0252	asparaginase activity
J8Y18_07640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y18_07655	COG0142	geranyltranstransferase activity
J8Y18_07665	COG0142	geranyltranstransferase activity
J8Y18_07690	COG0457	Tetratricopeptide repeat
J8Y18_07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J8Y18_07715	COG2010	Cytochrome c
J8Y18_07715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J8Y18_07720	COG4347	Protein of unknown function (DUF1405)
J8Y18_07735	COG2738	Putative neutral zinc metallopeptidase
J8Y18_07745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_07750	COG1694	Mazg nucleotide pyrophosphohydrolase
J8Y18_07770	COG0438	transferase activity, transferring glycosyl groups
J8Y18_07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J8Y18_07805	COG1199	ATP-dependent helicase activity
J8Y18_07825	COG3935	DnaD domain protein
J8Y18_07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J8Y18_07840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y18_07840	COG4499	WXG100 protein secretion system (Wss), protein YukC
J8Y18_07895	COG0116	Belongs to the methyltransferase superfamily
J8Y18_07905	COG1199	ATP-dependent helicase activity
J8Y18_07910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J8Y18_07920	COG0024	Methionine aminopeptidase
J8Y18_07930	COG2233	PERMEase
J8Y18_07935	COG2311	Membrane
J8Y18_07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y18_07955	COG0456	acetyltransferase
J8Y18_07990	COG0754	glutathionylspermidine amidase activity
J8Y18_08005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y18_08020	COG3944	biosynthesis protein
J8Y18_08030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8Y18_08045	COG1215	transferase activity, transferring glycosyl groups
J8Y18_08050	COG0438	transferase activity, transferring glycosyl groups
J8Y18_08065	COG0454	-acetyltransferase
J8Y18_08085	COG0328	RNA-DNA hybrid ribonuclease activity
J8Y18_08120	COG3403	YqcI/YcgG family
J8Y18_08125	COG1280	lysine exporter protein (LysE YggA)
J8Y18_08145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y18_08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y18_08160	COG0475	glutathione-regulated potassium exporter activity
J8Y18_08165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y18_08170	COG0789	Transcriptional regulator
J8Y18_08170	COG4978	Transcriptional regulator
J8Y18_08180	COG2323	membrane
J8Y18_08185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J8Y18_08220	COG1923	regulation of RNA biosynthetic process
J8Y18_08230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Y18_08235	COG1360	Flagellar Motor Protein
J8Y18_08240	COG2201	protein-glutamate methylesterase activity
J8Y18_08245	COG2198	Histidine kinase
J8Y18_08245	COG0643	Histidine kinase
J8Y18_08250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y18_08250	COG1776	CheC inhibitor of MCP methylation
J8Y18_08265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Y18_08285	COG1256	bacterial-type flagellum assembly
J8Y18_08290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y18_08310	COG1815	bacterial-type flagellum-dependent cell motility
J8Y18_08315	COG1558	bacterial-type flagellum-dependent cell motility
J8Y18_08325	COG1766	The M ring may be actively involved in energy transduction
J8Y18_08330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y18_08340	COG1157	protein secretion by the type III secretion system
J8Y18_08360	COG1749	Flagellar hook protein flgE
J8Y18_08375	COG0835	chemotaxis
J8Y18_08375	COG0784	Response regulator, receiver
J8Y18_08385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y18_08390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y18_08395	COG0741	lytic transglycosylase activity
J8Y18_08405	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y18_08410	COG1776	CheC inhibitor of MCP methylation
J8Y18_08410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y18_08420	COG1338	Plays a role in the flagellum-specific transport system
J8Y18_08425	COG1987	bacterial-type flagellum assembly
J8Y18_08435	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J8Y18_08440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J8Y18_08445	COG1419	protein localization to endoplasmic reticulum
J8Y18_08450	COG4786	Flagellar basal body rod
J8Y18_08455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8Y18_08490	COG2329	Antibiotic biosynthesis monooxygenase
J8Y18_08515	COG0583	DNA-binding transcription factor activity
J8Y18_08535	COG1234	tRNA 3'-trailer cleavage
J8Y18_08565	COG0406	alpha-ribazole phosphatase activity
J8Y18_08595	COG0367	asparagine synthase
J8Y18_08625	COG1802	Transcriptional regulator
J8Y18_08630	COG0697	spore germination
J8Y18_08640	COG0523	cobalamin synthesis protein
J8Y18_08645	COG0701	Predicted permease
J8Y18_08660	COG1757	Na H antiporter
J8Y18_08665	COG0789	Transcriptional regulator
J8Y18_08695	COG0534	Mate efflux family protein
J8Y18_08700	COG3340	Belongs to the peptidase S51 family
J8Y18_08720	COG0785	Cytochrome C biogenesis protein
J8Y18_08725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y18_08745	COG2733	membrane
J8Y18_08780	COG1131	(ABC) transporter
J8Y18_08795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y18_08800	COG0528	UMP kinase activity
J8Y18_08810	COG1027	Aspartate ammonia-lyase
J8Y18_08815	COG0281	malic enzyme
J8Y18_08820	COG4191	Histidine kinase
J8Y18_08825	COG0784	Response regulator, receiver
J8Y18_08830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y18_08885	COG1695	Transcriptional regulator
J8Y18_08895	COG0477	Major facilitator Superfamily
J8Y18_08905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J8Y18_08910	COG2223	nitrite transmembrane transporter activity
J8Y18_08915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y18_08935	COG0733	neurotransmitter:sodium symporter activity
J8Y18_08945	COG5566	PFAM Mor transcription activator
J8Y18_08950	COG2323	membrane
J8Y18_08970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y18_08980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y18_08985	COG0028	Belongs to the TPP enzyme family
J8Y18_09005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J8Y18_09030	COG2814	Major facilitator Superfamily
J8Y18_09035	COG3384	dioxygenase
J8Y18_09045	COG3279	Response regulator of the LytR AlgR family
J8Y18_09050	COG0427	acetyl-CoA hydrolase
J8Y18_09070	COG4166	transmembrane transport
J8Y18_09075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_09080	COG1914	H( )-stimulated, divalent metal cation uptake system
J8Y18_09095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J8Y18_09100	COG0531	amino acid
J8Y18_09120	COG2309	aminopeptidase activity
J8Y18_09135	COG0456	acetyltransferase
J8Y18_09150	COG1309	transcriptional regulator
J8Y18_09155	COG2390	Transcriptional regulator
J8Y18_09165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_09170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J8Y18_09180	COG4846	Membrane protein involved in cytochrome C biogenesis
J8Y18_09200	COG0583	DNA-binding transcription factor activity
J8Y18_09215	COG0006	proline dipeptidase activity
J8Y18_09225	COG2132	Multicopper oxidase
J8Y18_09235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Y18_09255	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_09265	COG1276	copper resistance
J8Y18_09265	COG2372	response to copper ion
J8Y18_09270	COG4549	nuclear export factor GLE1
J8Y18_09275	COG0697	spore germination
J8Y18_09280	COG0583	DNA-binding transcription factor activity
J8Y18_09285	COG1959	2 iron, 2 sulfur cluster binding
J8Y18_09290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J8Y18_09295	COG0778	Nitroreductase
J8Y18_09305	COG0628	permease
J8Y18_09315	COG1231	oxidoreductase activity
J8Y18_09320	COG0523	cobalamin synthesis protein
J8Y18_09330	COG0411	ABC transporter
J8Y18_09350	COG0583	DNA-binding transcription factor activity
J8Y18_09380	COG1271	oxidase subunit
J8Y18_09385	COG1294	oxidase, subunit
J8Y18_09390	COG4988	ABC transporter
J8Y18_09395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J8Y18_09405	COG1216	Glycosyl transferase, family 2
J8Y18_09445	COG1686	Belongs to the peptidase S11 family
J8Y18_09460	COG1388	LysM domain
J8Y18_09460	COG0791	NLP P60 protein
J8Y18_09470	COG1132	(ABC) transporter
J8Y18_09475	COG0745	RESPONSE REGULATOR receiver
J8Y18_09480	COG5002	protein histidine kinase activity
J8Y18_09490	COG0300	oxidoreductase activity
J8Y18_09520	COG0460	homoserine dehydrogenase
J8Y18_09545	COG1316	TRANSCRIPTIONal
J8Y18_09555	COG0745	RESPONSE REGULATOR receiver
J8Y18_09560	COG5002	protein histidine kinase activity
J8Y18_09575	COG1285	pathogenesis
J8Y18_09580	COG1247	-acetyltransferase
J8Y18_09600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y18_09610	COG1082	Xylose isomerase domain protein TIM barrel
J8Y18_09620	COG2814	Major facilitator Superfamily
J8Y18_09625	COG1279	arginine transmembrane transporter activity
J8Y18_09630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_09640	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8Y18_09675	COG0577	efflux transmembrane transporter activity
J8Y18_09680	COG2002	toxin-antitoxin pair type II binding
J8Y18_09685	COG1404	Belongs to the peptidase S8 family
J8Y18_09690	COG0640	Transcriptional regulator
J8Y18_09695	COG0667	Aldo Keto reductase
J8Y18_09700	COG2814	Major facilitator Superfamily
J8Y18_09705	COG3152	Membrane
J8Y18_09730	COG0840	transmembrane signaling receptor activity
J8Y18_09745	COG3949	Membrane
J8Y18_09750	COG0783	Belongs to the Dps family
J8Y18_09765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8Y18_09775	COG1231	oxidoreductase activity
J8Y18_09780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_09785	COG4989	oxidoreductase activity
J8Y18_09790	COG0523	cobalamin synthesis protein
J8Y18_09795	COG0456	acetyltransferase
J8Y18_09800	COG0803	Belongs to the bacterial solute-binding protein 9 family
J8Y18_09810	COG0702	epimerase
J8Y18_09820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J8Y18_09830	COG4166	transmembrane transport
J8Y18_09855	COG5337	Spore coat protein CotH
J8Y18_09860	COG1051	belongs to the nudix hydrolase family
J8Y18_09865	COG0586	Pfam SNARE associated Golgi protein
J8Y18_09870	COG2244	polysaccharide biosynthetic process
J8Y18_09880	COG0701	Predicted permease
J8Y18_09885	COG3689	TIGRFAM TIGR03943 family protein
J8Y18_09890	COG1607	acyl-coa hydrolase
J8Y18_09900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y18_09915	COG0702	epimerase
J8Y18_09920	COG2839	Protein conserved in bacteria
J8Y18_09925	COG1253	flavin adenine dinucleotide binding
J8Y18_09940	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_09945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y18_09965	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y18_09975	COG1876	peptidase activity
J8Y18_09985	COG0154	amidase activity
J8Y18_09990	COG2211	Major facilitator Superfamily
J8Y18_10005	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y18_10015	COG0561	phosphatase activity
J8Y18_10030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Y18_10045	COG1819	glycosyl
J8Y18_10050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_10055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_10085	COG0456	acetyltransferase
J8Y18_10120	COG4499	WXG100 protein secretion system (Wss), protein YukC
J8Y18_10275	COG4974	Belongs to the 'phage' integrase family
J8Y18_10285	COG3874	Sporulation protein YtfJ
J8Y18_10310	COG2226	methyltransferase
J8Y18_10330	COG1082	Xylose isomerase domain protein TIM barrel
J8Y18_10335	COG0346	lactoylglutathione lyase activity
J8Y18_10345	COG0604	alcohol dehydrogenase
J8Y18_10350	COG1595	DNA-templated transcription, initiation
J8Y18_10365	COG0426	domain, Protein
J8Y18_10365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8Y18_10375	COG0386	Belongs to the glutathione peroxidase family
J8Y18_10380	COG1305	Transglutaminase-like
J8Y18_10385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J8Y18_10390	COG0714	Associated with various cellular activities
J8Y18_10415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J8Y18_10430	COG2359	stage V sporulation protein S
J8Y18_10440	COG1418	mRNA catabolic process
J8Y18_10445	COG0488	(ABC) transporter
J8Y18_10470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J8Y18_10515	COG1413	lyase activity
J8Y18_10530	COG2136	Putative SAM-dependent methyltransferase
J8Y18_10530	COG2521	methyltransferase
J8Y18_10535	COG0018	arginyl-trna synthetase
J8Y18_10585	COG0017	Asparaginyl-tRNA synthetase
J8Y18_10590	COG0733	neurotransmitter:sodium symporter activity
J8Y18_10615	COG2610	gluconate transmembrane transporter activity
J8Y18_10625	COG1794	racemase activity, acting on amino acids and derivatives
J8Y18_10635	COG0456	acetyltransferase
J8Y18_10645	COG3655	Transcriptional regulator
J8Y18_10650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J8Y18_10660	COG1131	(ABC) transporter
J8Y18_10665	COG4473	ABC transporter
J8Y18_10675	COG0546	phosphoglycolate phosphatase activity
J8Y18_10690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y18_10705	COG0768	penicillin binding
J8Y18_10715	COG0204	Acyl-transferase
J8Y18_10720	COG1272	protein, Hemolysin III
J8Y18_10730	COG0805	protein transport
J8Y18_10740	COG1307	EDD domain protein, DegV family
J8Y18_10750	COG1999	signal sequence binding
J8Y18_10755	COG0071	Belongs to the small heat shock protein (HSP20) family
J8Y18_10760	COG0367	asparagine synthase
J8Y18_10775	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y18_10780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_10785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y18_10805	COG1335	isochorismatase
J8Y18_10815	COG0668	transmembrane transport
J8Y18_10820	COG2203	Gaf domain
J8Y18_10820	COG4585	Histidine kinase
J8Y18_10825	COG2197	response regulator
J8Y18_10830	COG1737	Transcriptional regulator
J8Y18_10835	COG0384	phenazine biosynthesis protein PhzF
J8Y18_10840	COG1064	alcohol dehydrogenase
J8Y18_10865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J8Y18_10900	COG0517	IMP dehydrogenase activity
J8Y18_10900	COG1125	glycine betaine transport
J8Y18_10905	COG1174	glycine betaine transport
J8Y18_10940	COG1253	flavin adenine dinucleotide binding
J8Y18_10945	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_10950	COG5506	Protein of unknown function (DUF1694)
J8Y18_10965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y18_10970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J8Y18_10975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J8Y18_10980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y18_10985	COG0456	acetyltransferase
J8Y18_10990	COG3829	transcription factor binding
J8Y18_10995	COG1509	lysine 2,3-aminomutase activity
J8Y18_11030	COG0515	serine threonine protein kinase
J8Y18_11030	COG3064	Membrane
J8Y18_11030	COG4991	sh3 domain protein
J8Y18_11040	COG0671	phosphoesterase, PA-phosphatase related
J8Y18_11045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8Y18_11050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y18_11135	COG0300	oxidoreductase activity
J8Y18_11155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y18_11155	COG4499	WXG100 protein secretion system (Wss), protein YukC
J8Y18_11165	COG2814	Major facilitator Superfamily
J8Y18_11170	COG4841	protein insertion into membrane
J8Y18_11175	COG0372	Belongs to the citrate synthase family
J8Y18_11180	COG2079	MmgE PrpD family protein
J8Y18_11185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J8Y18_11190	COG1960	acyl-CoA dehydrogenase activity
J8Y18_11195	COG2084	Dehydrogenase
J8Y18_11205	COG1280	lysine exporter protein (LysE YggA)
J8Y18_11210	COG1024	Enoyl-CoA hydratase
J8Y18_11225	COG0420	3'-5' exonuclease activity
J8Y18_11230	COG0419	ATPase involved in DNA repair
J8Y18_11235	COG0582	viral genome integration into host DNA
J8Y18_11265	COG1484	DNA-dependent DNA replication
J8Y18_11325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y18_11325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y18_11390	COG0270	DNA (cytosine-5-)-methyltransferase activity
J8Y18_11465	COG0582	viral genome integration into host DNA
J8Y18_11625	COG2223	nitrite transmembrane transporter activity
J8Y18_11630	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_11635	COG1169	isochorismate synthase
J8Y18_11640	COG1021	2,3-dihydroxybenzoate-AMP ligase
J8Y18_11645	COG3433	isochorismatase activity
J8Y18_11645	COG1535	isochorismatase
J8Y18_11650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J8Y18_11655	COG3251	PFAM MbtH domain protein
J8Y18_11660	COG2814	Major facilitator Superfamily
J8Y18_11675	COG0776	regulation of translation
J8Y18_11685	COG2318	DinB family
J8Y18_11695	COG1115	amino acid carrier protein
J8Y18_11715	COG1187	pseudouridine synthase activity
J8Y18_11720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8Y18_11725	COG1136	(ABC) transporter
J8Y18_11750	COG0028	Belongs to the TPP enzyme family
J8Y18_11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Y18_11805	COG1846	Transcriptional regulator
J8Y18_11845	COG1247	-acetyltransferase
J8Y18_11870	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J8Y18_11880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_11910	COG0583	DNA-binding transcription factor activity
J8Y18_11915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Y18_11935	COG0583	DNA-binding transcription factor activity
J8Y18_11940	COG2258	MOSC domain
J8Y18_11955	COG1132	(ABC) transporter
J8Y18_11960	COG1132	(ABC) transporter
J8Y18_11985	COG1396	sequence-specific DNA binding
J8Y18_12020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Y18_12025	COG1595	DNA-templated transcription, initiation
J8Y18_12050	COG1649	PFAM Uncharacterised BCR, COG1649
J8Y18_12075	COG2971	BadF BadG BcrA BcrD
J8Y18_12085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J8Y18_12095	COG1846	Transcriptional regulator
J8Y18_12110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_12130	COG1309	transcriptional regulator
J8Y18_12150	COG0500	methyltransferase
J8Y18_12150	COG3615	Tellurite resistance protein tehB
J8Y18_12160	COG2226	methyltransferase
J8Y18_12165	COG3961	Belongs to the TPP enzyme family
J8Y18_12170	COG1846	Transcriptional regulator
J8Y18_12200	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Y18_12230	COG2002	toxin-antitoxin pair type II binding
J8Y18_12240	COG0730	response to heat
J8Y18_12245	COG0110	maltose O-acetyltransferase activity
J8Y18_12250	COG1686	Belongs to the peptidase S11 family
J8Y18_12265	COG2814	Major facilitator Superfamily
J8Y18_12300	COG2312	Erythromycin esterase
J8Y18_12305	COG0741	lytic transglycosylase activity
J8Y18_12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_12345	COG1760	l-serine dehydratase
J8Y18_12350	COG1760	l-serine dehydratase
J8Y18_12355	COG0814	amino acid
J8Y18_12370	COG1309	transcriptional regulator
J8Y18_12375	COG2814	Major facilitator Superfamily
J8Y18_12390	COG0076	glutamate decarboxylase activity
J8Y18_12405	COG1280	lysine exporter protein (LysE YggA)
J8Y18_12420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y18_12425	COG0772	Belongs to the SEDS family
J8Y18_12430	COG2239	Acts as a magnesium transporter
J8Y18_12440	COG0768	penicillin binding
J8Y18_12445	COG1595	DNA-templated transcription, initiation
J8Y18_12455	COG0768	penicillin binding
J8Y18_12460	COG0768	penicillin binding
J8Y18_12470	COG1408	metallophosphoesterase
J8Y18_12480	COG1131	(ABC) transporter
J8Y18_12505	COG1960	acyl-CoA dehydrogenase activity
J8Y18_12510	COG0439	Biotin carboxylase
J8Y18_12515	COG0511	ligase activity, forming carbon-carbon bonds
J8Y18_12520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J8Y18_12525	COG1024	Enoyl-CoA hydratase
J8Y18_12530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J8Y18_12535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y18_12565	COG0572	uridine kinase
J8Y18_12585	COG1686	Belongs to the peptidase S11 family
J8Y18_12610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J8Y18_12630	COG3227	Zinc metalloprotease (Elastase)
J8Y18_12635	COG2207	Transcriptional regulator
J8Y18_12665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J8Y18_12675	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_12680	COG1733	regulation of RNA biosynthetic process
J8Y18_12725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_12730	COG2368	4-hydroxyphenylacetate
J8Y18_12745	COG1063	alcohol dehydrogenase
J8Y18_12755	COG2323	membrane
J8Y18_12760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8Y18_12770	COG3386	PFAM SMP-30 Gluconolaconase
J8Y18_12780	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J8Y18_12785	COG3773	Cell wall hydrolase
J8Y18_12795	COG0745	RESPONSE REGULATOR receiver
J8Y18_12800	COG2205	protein histidine kinase activity
J8Y18_12810	COG0488	(ABC) transporter
J8Y18_12820	COG1136	(ABC) transporter
J8Y18_12825	COG0577	efflux transmembrane transporter activity
J8Y18_12845	COG0460	homoserine dehydrogenase
J8Y18_12850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_12860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J8Y18_12920	COG2124	cytochrome p450
J8Y18_12955	COG0561	phosphatase activity
J8Y18_12960	COG5002	protein histidine kinase activity
J8Y18_12965	COG0768	penicillin binding
J8Y18_12975	COG1819	glycosyl
J8Y18_12980	COG1794	racemase activity, acting on amino acids and derivatives
J8Y18_13005	COG2205	protein histidine kinase activity
J8Y18_13075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y18_13080	COG0604	alcohol dehydrogenase
J8Y18_13085	COG0671	phosphoesterase, PA-phosphatase related
J8Y18_13090	COG0768	penicillin binding
J8Y18_13135	COG0693	protein deglycase activity
J8Y18_13145	COG2814	Major facilitator Superfamily
J8Y18_13160	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y18_13185	COG0697	spore germination
J8Y18_13220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y18_13230	COG2223	nitrite transmembrane transporter activity
J8Y18_13245	COG0592	DNA-directed DNA polymerase activity
J8Y18_13265	COG0251	oxidation-reduction process
J8Y18_13270	COG3878	Protein conserved in bacteria
J8Y18_13290	COG4667	esterase of the alpha-beta hydrolase superfamily
J8Y18_13330	COG0322	excinuclease ABC activity
J8Y18_13370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y18_13400	COG1011	Hydrolase
J8Y18_13405	COG0745	RESPONSE REGULATOR receiver
J8Y18_13410	COG5002	protein histidine kinase activity
J8Y18_13425	COG1136	(ABC) transporter
J8Y18_13430	COG0577	efflux transmembrane transporter activity
J8Y18_13435	COG1073	alpha beta
J8Y18_13445	COG1523	belongs to the glycosyl hydrolase 13 family
J8Y18_13450	COG3227	Zinc metalloprotease (Elastase)
J8Y18_13455	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_13470	COG0201	protein transport
J8Y18_13475	COG0697	spore germination
J8Y18_13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_13490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8Y18_13520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_13535	COG2959	enzyme of heme biosynthesis
J8Y18_13575	COG1309	transcriptional regulator
J8Y18_13595	COG3284	Transcriptional regulator
J8Y18_13610	COG1349	DNA-binding transcription factor activity
J8Y18_13625	COG1959	2 iron, 2 sulfur cluster binding
J8Y18_13640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Y18_13645	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y18_13650	COG0022	dehydrogenase e1 component
J8Y18_13655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y18_13670	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_13675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y18_13675	COG0456	acetyltransferase
J8Y18_13715	COG4176	ABC-type proline glycine betaine transport system permease component
J8Y18_13720	COG4175	Glycine betaine
J8Y18_13720	COG0517	IMP dehydrogenase activity
J8Y18_13750	COG2153	protein acetylation
J8Y18_13755	COG3397	chitin binding
J8Y18_13760	COG1819	glycosyl
J8Y18_13780	COG2205	protein histidine kinase activity
J8Y18_13785	COG2226	methyltransferase
J8Y18_13790	COG2315	Protein conserved in bacteria
J8Y18_13835	COG0456	acetyltransferase
J8Y18_13840	COG3973	AAA domain
J8Y18_13855	COG0514	ATP-dependent DNA helicase (RecQ)
J8Y18_13895	COG4637	Psort location Cytoplasmic, score
J8Y18_13910	COG3397	chitin binding
J8Y18_13925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J8Y18_13930	COG1115	amino acid carrier protein
J8Y18_13935	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_13940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J8Y18_13950	COG3938	Belongs to the proline racemase family
J8Y18_13955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y18_13995	COG0586	Pfam SNARE associated Golgi protein
J8Y18_14005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J8Y18_14015	COG4166	transmembrane transport
J8Y18_14025	COG4948	Mandelate Racemase Muconate Lactonizing
J8Y18_14040	COG0667	Aldo Keto reductase
J8Y18_14085	COG5002	protein histidine kinase activity
J8Y18_14085	COG3850	Histidine kinase
J8Y18_14090	COG0745	RESPONSE REGULATOR receiver
J8Y18_14130	COG1164	Oligoendopeptidase f
J8Y18_14135	COG1307	EDD domain protein, DegV family
J8Y18_14175	COG2814	Major facilitator Superfamily
J8Y18_14185	COG1664	Polymer-forming cytoskeletal
J8Y18_14190	COG0789	Transcriptional regulator
J8Y18_14195	COG4533	DNA binding
J8Y18_14200	COG0477	Major facilitator Superfamily
J8Y18_14200	COG2814	Major facilitator Superfamily
J8Y18_14220	COG2261	transglycosylase associated protein
J8Y18_14235	COG2226	methyltransferase
J8Y18_14270	COG0436	Aminotransferase
J8Y18_14275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J8Y18_14300	COG1131	(ABC) transporter
J8Y18_14350	COG0628	permease
J8Y18_14360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8Y18_14365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y18_14370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y18_14410	COG2746	aminoglycoside 3-N-acetyltransferase activity
J8Y18_14420	COG0697	spore germination
J8Y18_14445	COG4912	Dna alkylation repair
J8Y18_14450	COG0346	lactoylglutathione lyase activity
J8Y18_14455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_14470	COG0861	Integral membrane protein TerC family
J8Y18_14475	COG1368	sulfuric ester hydrolase activity
J8Y18_14480	COG0488	(ABC) transporter
J8Y18_14490	COG1033	growth of symbiont in host cell
J8Y18_14490	COG2409	Drug exporters of the RND superfamily
J8Y18_14495	COG1309	transcriptional regulator
J8Y18_14510	COG0287	Prephenate dehydrogenase
J8Y18_14525	COG1605	Chorismate mutase
J8Y18_14525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J8Y18_14570	COG3584	3D domain protein
J8Y18_14570	COG1388	LysM domain
J8Y18_14580	COG0346	lactoylglutathione lyase activity
J8Y18_14610	COG1879	ABC-type sugar transport system periplasmic component
J8Y18_14615	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Y18_14620	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Y18_14630	COG2390	Transcriptional regulator
J8Y18_14635	COG1070	Carbohydrate kinase
J8Y18_14655	COG2329	Antibiotic biosynthesis monooxygenase
J8Y18_14675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_14690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y18_14695	COG4187	Peptidase family M20/M25/M40
J8Y18_14700	COG1414	Transcriptional regulator
J8Y18_14705	COG0833	amino acid
J8Y18_14715	COG3239	Fatty acid desaturase
J8Y18_14725	COG2720	vancomycin resistance protein
J8Y18_14730	COG1785	Belongs to the alkaline phosphatase family
J8Y18_14740	COG3655	Transcriptional regulator
J8Y18_14760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_14765	COG0346	lactoylglutathione lyase activity
J8Y18_14790	COG0714	Associated with various cellular activities
J8Y18_14815	COG0463	Glycosyl transferase, family 2
J8Y18_14845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8Y18_14850	COG0753	catalase activity
J8Y18_14890	COG0714	Associated with various cellular activities
J8Y18_14995	COG0778	Nitroreductase
J8Y18_15000	COG1846	Transcriptional regulator
J8Y18_15020	COG0179	Fumarylacetoacetate (FAA) hydrolase
J8Y18_15030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8Y18_15040	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_15045	COG0183	Belongs to the thiolase family
J8Y18_15050	COG1024	Enoyl-CoA hydratase
J8Y18_15055	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8Y18_15060	COG2723	6-phospho-beta-galactosidase activity
J8Y18_15065	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y18_15070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y18_15085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y18_15095	COG2508	Transcriptional regulator
J8Y18_15100	COG2814	Major facilitator Superfamily
J8Y18_15145	COG0456	acetyltransferase
J8Y18_15165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_15220	COG0730	response to heat
J8Y18_15230	COG0833	amino acid
J8Y18_15240	COG4335	DNA alkylation repair
J8Y18_15270	COG0768	penicillin binding
J8Y18_15300	COG1984	allophanate hydrolase subunit 2
J8Y18_15305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J8Y18_15310	COG1414	Transcriptional regulator
J8Y18_15325	COG0640	Transcriptional regulator
J8Y18_15335	COG1960	acyl-CoA dehydrogenase activity
J8Y18_15350	COG3314	Sporulation integral membrane protein YlbJ
J8Y18_15370	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
J8Y18_15395	COG0574	Belongs to the PEP-utilizing enzyme family
J8Y18_15395	COG3848	Pyruvate phosphate dikinase
J8Y18_15400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_15420	COG1063	alcohol dehydrogenase
J8Y18_15425	COG1027	Aspartate ammonia-lyase
J8Y18_15430	COG0252	asparaginase activity
J8Y18_15435	COG1396	sequence-specific DNA binding
J8Y18_15470	COG5002	protein histidine kinase activity
J8Y18_15495	COG2207	Transcriptional regulator
J8Y18_15510	COG0322	excinuclease ABC activity
J8Y18_15515	COG0531	amino acid
J8Y18_15520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y18_15530	COG0531	amino acid
J8Y18_15535	COG0697	spore germination
J8Y18_15540	COG0784	Response regulator, receiver
J8Y18_15545	COG4191	Histidine kinase
J8Y18_15555	COG1115	amino acid carrier protein
J8Y18_15565	COG2124	cytochrome p450
J8Y18_15580	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_15585	COG2267	carboxylic ester hydrolase activity
J8Y18_15590	COG1335	isochorismatase
J8Y18_15610	COG0583	DNA-binding transcription factor activity
J8Y18_15615	COG1846	Transcriptional regulator
J8Y18_15620	COG0598	Magnesium transport protein CorA
J8Y18_15640	COG1073	alpha beta
J8Y18_15660	COG0415	Belongs to the DNA photolyase family
J8Y18_15675	COG0288	reversible hydration of carbon dioxide
J8Y18_15685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J8Y18_15690	COG5609	conserved protein (DUF2294)
J8Y18_15705	COG0697	spore germination
J8Y18_15715	COG0456	acetyltransferase
J8Y18_15720	COG1575	Belongs to the MenA family. Type 1 subfamily
J8Y18_15730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_15740	COG0798	PFAM Bile acid sodium symporter
J8Y18_15745	COG0346	lactoylglutathione lyase activity
J8Y18_15750	COG0640	Transcriptional regulator
J8Y18_15760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J8Y18_15765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y18_15765	COG3320	Male sterility
J8Y18_15770	COG1309	transcriptional regulator
J8Y18_15775	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_15780	COG1522	sequence-specific DNA binding
J8Y18_15795	COG0346	lactoylglutathione lyase activity
J8Y18_15825	COG1309	transcriptional regulator
J8Y18_15880	COG0745	RESPONSE REGULATOR receiver
J8Y18_15885	COG3850	Histidine kinase
J8Y18_15885	COG5002	protein histidine kinase activity
J8Y18_15925	COG1136	(ABC) transporter
J8Y18_15960	COG2814	Major facilitator Superfamily
J8Y18_15970	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J8Y18_15980	COG1690	Belongs to the RtcB family
J8Y18_15990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J8Y18_16010	COG0577	efflux transmembrane transporter activity
J8Y18_16030	COG3850	Histidine kinase
J8Y18_16030	COG5002	protein histidine kinase activity
J8Y18_16040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_16070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J8Y18_16090	COG0662	Cupin 2, conserved barrel domain protein
J8Y18_16095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_16095	COG2207	Transcriptional regulator
J8Y18_16110	COG5632	N-Acetylmuramoyl-L-alanine amidase
J8Y18_16110	COG3409	Peptidoglycan-binding domain 1 protein
J8Y18_16205	COG1876	peptidase activity
J8Y18_16210	COG2843	Capsule synthesis protein
J8Y18_16220	COG0477	Major facilitator Superfamily
J8Y18_16235	COG1846	Transcriptional regulator
J8Y18_16240	COG2814	Major facilitator Superfamily
J8Y18_16250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J8Y18_16255	COG1131	(ABC) transporter
J8Y18_16270	COG2031	fatty acid transporter
J8Y18_16280	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y18_16335	COG1288	antiporter activity
J8Y18_16340	COG2356	endonuclease I
J8Y18_16360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J8Y18_16380	COG1733	regulation of RNA biosynthetic process
J8Y18_16385	COG0778	Nitroreductase
J8Y18_16415	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_16425	COG1131	(ABC) transporter
J8Y18_16450	COG1011	Hydrolase
J8Y18_16455	COG2365	Tyrosine phosphatase family
J8Y18_16490	COG0628	permease
J8Y18_16520	COG0500	methyltransferase
J8Y18_16530	COG0477	Major facilitator Superfamily
J8Y18_16560	COG1253	flavin adenine dinucleotide binding
J8Y18_16565	COG0789	Transcriptional regulator
J8Y18_16575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J8Y18_16605	COG0697	spore germination
J8Y18_16615	COG1357	PFAM Pentapeptide repeats (8 copies)
J8Y18_16620	COG3813	Protein conserved in bacteria
J8Y18_16625	COG2706	6-phosphogluconolactonase activity
J8Y18_16630	COG1070	Carbohydrate kinase
J8Y18_16645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J8Y18_16650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J8Y18_16655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J8Y18_16665	COG0604	alcohol dehydrogenase
J8Y18_16670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8Y18_16680	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_16695	COG0840	transmembrane signaling receptor activity
J8Y18_16705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y18_16705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y18_16710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J8Y18_16710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J8Y18_16715	COG1733	regulation of RNA biosynthetic process
J8Y18_16730	COG0656	L-ascorbic acid biosynthetic process
J8Y18_16735	COG2814	Major facilitator Superfamily
J8Y18_16760	COG2824	Alkylphosphonate utilization operon protein PhnA
J8Y18_16765	COG0659	secondary active sulfate transmembrane transporter activity
J8Y18_16780	COG0814	amino acid
J8Y18_16815	COG1733	regulation of RNA biosynthetic process
J8Y18_16820	COG2188	Transcriptional regulator
J8Y18_16825	COG0673	inositol 2-dehydrogenase activity
J8Y18_16830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J8Y18_16835	COG1733	regulation of RNA biosynthetic process
J8Y18_16840	COG1733	regulation of RNA biosynthetic process
J8Y18_16865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_16885	COG0384	phenazine biosynthesis protein PhzF
J8Y18_16895	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_16900	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y18_16905	COG1733	regulation of RNA biosynthetic process
J8Y18_16920	COG0726	polysaccharide deacetylase
J8Y18_16930	COG1191	sigma factor activity
J8Y18_16980	COG1151	hydroxylamine reductase activity
J8Y18_16990	COG3409	Peptidoglycan-binding domain 1 protein
J8Y18_16990	COG3757	hydrolase, family 25
J8Y18_17025	COG2072	flavoprotein involved in K transport
J8Y18_17060	COG1113	amino acid transport
J8Y18_17065	COG0456	acetyltransferase
J8Y18_17075	COG2814	Major facilitator Superfamily
J8Y18_17105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J8Y18_17110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y18_17125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_17135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_17140	COG3739	integral membrane protein
J8Y18_17160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_17175	COG0583	DNA-binding transcription factor activity
J8Y18_17195	COG1193	negative regulation of DNA recombination
J8Y18_17205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J8Y18_17210	COG1164	Oligoendopeptidase f
J8Y18_17235	COG3781	membrane
J8Y18_17250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y18_17275	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y18_17285	COG0640	Transcriptional regulator
J8Y18_17290	COG0604	alcohol dehydrogenase
J8Y18_17300	COG0457	Tetratricopeptide repeat
J8Y18_17315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y18_17330	COG0277	FAD linked oxidase domain protein
J8Y18_17355	COG1183	phosphatidylcholine synthase activity
J8Y18_17360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_17360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_17365	COG1252	NADH dehydrogenase
J8Y18_17375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J8Y18_17385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y18_17395	COG0457	Tetratricopeptide repeat
J8Y18_17450	COG0488	(ABC) transporter
J8Y18_17480	COG3852	Histidine kinase
J8Y18_17490	COG1285	pathogenesis
J8Y18_17500	COG2514	catechol 2,3-dioxygenase activity
J8Y18_17505	COG2720	vancomycin resistance protein
J8Y18_17540	COG0716	FMN binding
J8Y18_17550	COG0494	nUDIX hydrolase
J8Y18_17570	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_17580	COG0165	Argininosuccinate lyase
J8Y18_17595	COG4145	pantothenate transmembrane transporter activity
J8Y18_17605	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_17610	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_17620	COG1657	PFAM Prenyltransferase squalene oxidase
J8Y18_17625	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J8Y18_17630	COG2962	Rard protein
J8Y18_17635	COG3326	Membrane
J8Y18_17650	COG0489	protein tyrosine kinase activity
J8Y18_17660	COG0314	molybdopterin synthase activity
J8Y18_17665	COG0303	'Molybdopterin
J8Y18_17670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y18_17675	COG2116	formate transmembrane transporter activity
J8Y18_17685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J8Y18_17690	COG5609	conserved protein (DUF2294)
J8Y18_17695	COG2427	Protein of unknown function (DUF1641)
J8Y18_17700	COG3383	formate dehydrogenase (NAD+) activity
J8Y18_17705	COG0697	spore germination
J8Y18_17720	COG0531	amino acid
J8Y18_17755	COG2226	methyltransferase
J8Y18_17760	COG4166	transmembrane transport
J8Y18_17765	COG4166	transmembrane transport
J8Y18_17770	COG4166	transmembrane transport
J8Y18_17775	COG1301	dicarboxylic acid transport
J8Y18_17780	COG1316	TRANSCRIPTIONal
J8Y18_17790	COG1595	DNA-templated transcription, initiation
J8Y18_17800	COG1131	(ABC) transporter
J8Y18_17810	COG0673	inositol 2-dehydrogenase activity
J8Y18_17815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J8Y18_17820	COG0187	DNA topoisomerase II activity
J8Y18_17825	COG1832	CoA-binding protein
J8Y18_17830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y18_17835	COG0745	RESPONSE REGULATOR receiver
J8Y18_17855	COG4841	protein insertion into membrane
J8Y18_17860	COG0824	Thioesterase
J8Y18_17890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y18_17905	COG1132	(ABC) transporter
J8Y18_17910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J8Y18_17940	COG2211	Major facilitator Superfamily
J8Y18_17950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8Y18_17965	COG0183	Belongs to the thiolase family
J8Y18_17970	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_17975	COG1268	BioY protein
J8Y18_17980	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_18025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_18035	COG5002	protein histidine kinase activity
J8Y18_18040	COG0400	carboxylic ester hydrolase activity
J8Y18_18045	COG0346	lactoylglutathione lyase activity
J8Y18_18050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y18_18055	COG0069	glutamate synthase activity
J8Y18_18060	COG1902	pentaerythritol trinitrate reductase activity
J8Y18_18065	COG1329	Transcriptional regulator
J8Y18_18070	COG0010	Belongs to the arginase family
J8Y18_18120	COG4846	Membrane protein involved in cytochrome C biogenesis
J8Y18_18125	COG0785	Cytochrome C biogenesis protein
J8Y18_18135	COG1473	amidohydrolase
J8Y18_18145	COG1131	(ABC) transporter
J8Y18_18160	COG0583	DNA-binding transcription factor activity
J8Y18_18170	COG1346	cytolysis
J8Y18_18185	COG0730	response to heat
J8Y18_18210	COG1132	(ABC) transporter
J8Y18_18215	COG1132	(ABC) transporter
J8Y18_18240	COG3639	organic phosphonate transmembrane transporter activity
J8Y18_18250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y18_18255	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_18265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J8Y18_18285	COG1695	Transcriptional regulator
J8Y18_18290	COG0174	glutamine synthetase
J8Y18_18295	COG0789	Transcriptional regulator
J8Y18_18300	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J8Y18_18305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J8Y18_18310	COG2860	membrane
J8Y18_18320	COG0464	growth
J8Y18_18350	COG3584	3D domain protein
J8Y18_18350	COG1388	LysM domain
J8Y18_18355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y18_18355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Y18_18355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Y18_18360	COG1105	Belongs to the carbohydrate kinase PfkB family
J8Y18_18365	COG1349	DNA-binding transcription factor activity
J8Y18_18370	COG1979	alcohol dehydrogenase
J8Y18_18375	COG2322	membrane
J8Y18_18385	COG1113	amino acid transport
J8Y18_18395	COG1408	metallophosphoesterase
J8Y18_18400	COG2116	formate transmembrane transporter activity
J8Y18_18415	COG2217	Heavy metal translocating P-type atpase
J8Y18_18420	COG2608	mercury ion transmembrane transporter activity
J8Y18_18425	COG1937	Protein conserved in bacteria
J8Y18_18435	COG2819	hydrolase of the alpha beta superfamily
J8Y18_18440	COG1120	ATPase activity
J8Y18_18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_18455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_18460	COG0708	Exodeoxyribonuclease III
J8Y18_18465	COG2169	Transcriptional regulator
J8Y18_18470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J8Y18_18475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J8Y18_18495	COG2267	carboxylic ester hydrolase activity
J8Y18_18500	COG5001	Diguanylate cyclase
J8Y18_18500	COG3300	MHYT domain
J8Y18_18520	COG1086	Polysaccharide biosynthesis protein
J8Y18_18540	COG1346	cytolysis
J8Y18_18550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y18_18560	COG2188	Transcriptional regulator
J8Y18_18565	COG2723	6-phospho-beta-galactosidase activity
J8Y18_18575	COG1404	Belongs to the peptidase S8 family
J8Y18_18580	COG3773	Cell wall hydrolase
J8Y18_18590	COG1368	sulfuric ester hydrolase activity
J8Y18_18595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y18_18620	COG4550	Control of competence regulator ComK, YlbF/YmcA
J8Y18_18630	COG1013	pyruvate-flavodoxin oxidoreductase activity
J8Y18_18635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J8Y18_18635	COG0674	pyruvate-flavodoxin oxidoreductase activity
J8Y18_18645	COG2359	stage V sporulation protein S
J8Y18_18650	COG1692	metallophosphoesterase
J8Y18_18670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J8Y18_18675	COG1426	Protein conserved in bacteria
J8Y18_18690	COG0300	oxidoreductase activity
J8Y18_18695	COG0612	Peptidase, M16
J8Y18_18700	COG0612	Peptidase, M16
J8Y18_18705	COG1079	Belongs to the binding-protein-dependent transport system permease family
J8Y18_18710	COG4603	Belongs to the binding-protein-dependent transport system permease family
J8Y18_18715	COG3845	ABC transporter
J8Y18_18720	COG1744	ABC transporter substrate-binding protein PnrA-like
J8Y18_18725	COG2188	Transcriptional regulator
J8Y18_18740	COG0740	serine-type endopeptidase activity
J8Y18_18745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y18_18755	COG0527	aspartate kinase activity
J8Y18_18760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Y18_18765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J8Y18_18770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Y18_18775	COG1873	PFAM PRC-barrel domain
J8Y18_18780	COG0612	Peptidase, M16
J8Y18_18785	COG0726	polysaccharide deacetylase
J8Y18_18800	COG0196	riboflavin kinase activity
J8Y18_18810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J8Y18_18815	COG1550	Protein conserved in bacteria
J8Y18_18825	COG1358	cellular component organization or biogenesis
J8Y18_18830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J8Y18_18835	COG0195	Participates in both transcription termination and antitermination
J8Y18_18855	COG0750	zinc metalloprotease
J8Y18_18865	COG4589	Belongs to the CDS family
J8Y18_18910	COG4974	Belongs to the 'phage' integrase family
J8Y18_18920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Y18_18925	COG0758	DNA mediated transformation
J8Y18_18930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J8Y18_18970	COG1837	Belongs to the UPF0109 family
J8Y18_18980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J8Y18_18990	COG0552	protein localization to endoplasmic reticulum
J8Y18_18995	COG1196	nuclear chromosome segregation
J8Y18_19005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y18_19010	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_19015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J8Y18_19030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J8Y18_19035	COG1461	Dihydroxyacetone kinase
J8Y18_19040	COG1302	Protein conserved in bacteria
J8Y18_19055	COG1564	THIamine pyrophosphokinase
J8Y18_19060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J8Y18_19070	COG0515	serine threonine protein kinase
J8Y18_19070	COG2815	serine threonine protein kinase
J8Y18_19075	COG0631	protein serine/threonine phosphatase activity
J8Y18_19085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8Y18_19085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8Y18_19100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J8Y18_19105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J8Y18_19125	COG1561	YicC-like family, N-terminal region
J8Y18_19130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J8Y18_19140	COG0006	proline dipeptidase activity
J8Y18_19150	COG3069	C4-dicarboxylate transmembrane transporter activity
J8Y18_19160	COG0546	phosphoglycolate phosphatase activity
J8Y18_19215	COG0564	pseudouridine synthase activity
J8Y18_19235	COG3599	regulation of cell shape
J8Y18_19240	COG2302	S4 RNA-binding domain
J8Y18_19245	COG0762	integral membrane protein
J8Y18_19255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J8Y18_19265	COG1873	PFAM PRC-barrel domain
J8Y18_19270	COG1191	sigma factor activity
J8Y18_19275	COG1191	sigma factor activity
J8Y18_19285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J8Y18_19290	COG0849	cell division
J8Y18_19310	COG0772	Belongs to the SEDS family
J8Y18_19330	COG0768	penicillin binding
J8Y18_19335	COG0768	penicillin binding
J8Y18_19355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J8Y18_19370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J8Y18_19375	COG1399	metal-binding, possibly nucleic acid-binding protein
J8Y18_19385	COG3480	Lon protease (S16) C-terminal proteolytic domain
J8Y18_19390	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8Y18_19395	COG3314	Sporulation integral membrane protein YlbJ
J8Y18_19405	COG0742	ribosomal rna small subunit methyltransferase
J8Y18_19420	COG3679	Belongs to the UPF0342 family
J8Y18_19425	COG0406	alpha-ribazole phosphatase activity
J8Y18_19440	COG2340	Cysteine-rich secretory protein family
J8Y18_19455	COG3336	cytochrome c oxidase
J8Y18_19490	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J8Y18_19495	COG0772	Belongs to the SEDS family
J8Y18_19505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J8Y18_19510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J8Y18_19520	COG4896	Protein conserved in bacteria
J8Y18_19535	COG1217	gtp-binding protein TYPA
J8Y18_19545	COG0483	inositol monophosphate 1-phosphatase activity
J8Y18_19565	COG1982	Orn Lys Arg decarboxylase major
J8Y18_19615	COG0022	dehydrogenase e1 component
J8Y18_19620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y18_19635	COG0561	phosphatase activity
J8Y18_19645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y18_19650	COG0569	domain protein
J8Y18_19670	COG0583	DNA-binding transcription factor activity
J8Y18_19675	COG0517	IMP dehydrogenase activity
J8Y18_19685	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J8Y18_19695	COG4703	Protein of unknown function (DUF1797)
J8Y18_19710	COG2200	EAL domain
J8Y18_19715	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_19720	COG1408	metallophosphoesterase
J8Y18_19765	COG2814	Major facilitator Superfamily
J8Y18_19785	COG3209	COG3209 Rhs family protein
J8Y18_19795	COG2205	protein histidine kinase activity
J8Y18_19805	COG0436	Aminotransferase
J8Y18_19810	COG1609	Transcriptional regulator
J8Y18_19815	COG3833	ABC-type maltose transport systems, permease component
J8Y18_19820	COG1175	transmembrane transport
J8Y18_19825	COG2182	Extracellular solute-binding protein
J8Y18_19835	COG0366	Alpha amylase catalytic
J8Y18_19840	COG3842	ATPase activity
J8Y18_19880	COG0183	Belongs to the thiolase family
J8Y18_19910	COG1695	Transcriptional regulator
J8Y18_19915	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_19935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8Y18_19940	COG0436	Aminotransferase
J8Y18_19975	COG2084	Dehydrogenase
J8Y18_19985	COG2199	diguanylate cyclase activity
J8Y18_19990	COG0778	Nitroreductase
J8Y18_20015	COG2190	(PTS) system
J8Y18_20015	COG1263	PTS System
J8Y18_20015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y18_20020	COG3711	transcriptional antiterminator
J8Y18_20030	COG2188	Transcriptional regulator
J8Y18_20040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J8Y18_20065	COG1547	Domain of unknown function (DUF309)
J8Y18_20070	COG0456	acetyltransferase
J8Y18_20075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J8Y18_20080	COG4086	secreted protein
J8Y18_20085	COG0561	phosphatase activity
J8Y18_20090	COG0697	spore germination
J8Y18_20105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y18_20130	COG0733	neurotransmitter:sodium symporter activity
J8Y18_20150	COG1686	Belongs to the peptidase S11 family
J8Y18_20155	COG1725	Transcriptional regulator
J8Y18_20160	COG1131	(ABC) transporter
J8Y18_20180	COG1846	Transcriptional regulator
J8Y18_20195	COG0598	Magnesium transport protein CorA
J8Y18_20220	COG4974	Belongs to the 'phage' integrase family
J8Y18_20230	COG0735	belongs to the Fur family
J8Y18_20235	COG1300	Membrane
J8Y18_20255	COG0667	Aldo Keto reductase
J8Y18_20260	COG0656	L-ascorbic acid biosynthetic process
J8Y18_20265	COG0456	acetyltransferase
J8Y18_20265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y18_20275	COG4085	toxin activity
J8Y18_20275	COG1525	nuclease
J8Y18_20275	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_20285	COG0596	Alpha beta hydrolase
J8Y18_20290	COG2056	Na+-H+ antiporter family
J8Y18_20295	COG1609	Transcriptional regulator
J8Y18_20300	COG0456	acetyltransferase
J8Y18_20305	COG1073	alpha beta
J8Y18_20320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y18_20320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y18_20325	COG0307	riboflavin synthase, alpha
J8Y18_20355	COG1073	alpha beta
J8Y18_20355	COG2226	methyltransferase
J8Y18_20370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y18_20380	COG1757	Na H antiporter
J8Y18_20385	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_20395	COG1522	sequence-specific DNA binding
J8Y18_20440	COG0300	oxidoreductase activity
J8Y18_20445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_20450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y18_20455	COG1760	l-serine dehydratase
J8Y18_20460	COG1760	l-serine dehydratase
J8Y18_20490	COG1285	pathogenesis
J8Y18_20500	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Y18_20505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_20520	COG1376	ErfK ybiS ycfS ynhG family protein
J8Y18_20525	COG4129	membrane
J8Y18_20530	COG1126	abc transporter atp-binding protein
J8Y18_20535	COG0765	amino acid transport
J8Y18_20540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y18_20560	COG2323	membrane
J8Y18_20565	COG0772	Belongs to the SEDS family
J8Y18_20570	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y18_20575	COG0022	dehydrogenase e1 component
J8Y18_20580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y18_20585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Y18_20600	COG0280	phosphate acetyltransferase
J8Y18_20605	COG3290	protein histidine kinase activity
J8Y18_20605	COG3829	transcription factor binding
J8Y18_20615	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y18_20620	COG3093	addiction module antidote protein HigA
J8Y18_20635	COG0750	zinc metalloprotease
J8Y18_20640	COG0497	DNA recombination
J8Y18_20650	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J8Y18_20660	COG0142	geranyltranstransferase activity
J8Y18_20685	COG1302	Protein conserved in bacteria
J8Y18_20690	COG0439	Biotin carboxylase
J8Y18_20695	COG0511	ligase activity, forming carbon-carbon bonds
J8Y18_20740	COG3854	ATPases associated with a variety of cellular activities
J8Y18_20765	COG0006	proline dipeptidase activity
J8Y18_20780	COG3872	metal-dependent enzyme
J8Y18_20790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J8Y18_20825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_20835	COG1609	Transcriptional regulator
J8Y18_20845	COG2076	Multidrug Resistance protein
J8Y18_20850	COG2076	Multidrug Resistance protein
J8Y18_20885	COG1131	(ABC) transporter
J8Y18_20890	COG1725	Transcriptional regulator
J8Y18_20920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y18_20985	COG1459	type II secretion system
J8Y18_20990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8Y18_21045	COG0646	methionine synthase
J8Y18_21045	COG1410	methionine synthase
J8Y18_21050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J8Y18_21050	COG0646	methionine synthase
J8Y18_21055	COG0626	cystathionine gamma-synthase activity
J8Y18_21060	COG0626	cystathionine gamma-synthase activity
J8Y18_21080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_21090	COG1940	carbohydrate kinase activity
J8Y18_21095	COG4483	Protein conserved in bacteria
J8Y18_21100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J8Y18_21105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J8Y18_21110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J8Y18_21115	COG0704	Plays a role in the regulation of phosphate uptake
J8Y18_21125	COG0573	inorganic phosphate transmembrane transporter activity
J8Y18_21130	COG0573	inorganic phosphate transmembrane transporter activity
J8Y18_21135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8Y18_21140	COG0768	penicillin binding
J8Y18_21145	COG0477	Major facilitator Superfamily
J8Y18_21150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Y18_21160	COG5521	maltodextrose utilization protein MalA
J8Y18_21175	COG0735	belongs to the Fur family
J8Y18_21180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J8Y18_21185	COG1121	(ABC) transporter
J8Y18_21190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_21220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J8Y18_21225	COG2384	SAM-dependent methyltransferase
J8Y18_21235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J8Y18_21240	COG0358	DNA primase activity
J8Y18_21255	COG0517	IMP dehydrogenase activity
J8Y18_21270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J8Y18_21275	COG0295	cytidine deaminase activity
J8Y18_21280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J8Y18_21290	COG1480	7TM receptor with intracellular HD hydrolase
J8Y18_21295	COG1702	phosphate starvation-inducible protein PhoH
J8Y18_21310	COG1610	YqeY-like protein
J8Y18_21315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J8Y18_21320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J8Y18_21325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J8Y18_21355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Y18_21360	COG1733	regulation of RNA biosynthetic process
J8Y18_21385	COG1466	dna polymerase III delta subunit
J8Y18_21395	COG0658	competence protein
J8Y18_21395	COG2333	competence protein COMEC
J8Y18_21400	COG2131	deaminase
J8Y18_21405	COG1555	photosystem II stabilization
J8Y18_21405	COG1596	polysaccharide export
J8Y18_21410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y18_21415	COG2226	methyltransferase
J8Y18_21420	COG0799	negative regulation of ribosome biogenesis
J8Y18_21425	COG1713	HD superfamily hydrolase involved in NAD metabolism
J8Y18_21435	COG1534	Rna-binding protein
J8Y18_21445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J8Y18_21450	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J8Y18_21485	COG0778	Nitroreductase
J8Y18_21490	COG2357	RelA SpoT domain protein
J8Y18_21500	COG1785	Belongs to the alkaline phosphatase family
J8Y18_21510	COG2267	carboxylic ester hydrolase activity
J8Y18_21550	COG1404	Belongs to the peptidase S8 family
J8Y18_21555	COG3186	Phenylalanine-4-hydroxylase
J8Y18_21565	COG2514	catechol 2,3-dioxygenase activity
J8Y18_21570	COG2259	Doxx family
J8Y18_21610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_21620	COG1012	belongs to the aldehyde dehydrogenase family
J8Y18_21620	COG1454	alcohol dehydrogenase
J8Y18_21625	COG0626	cystathionine gamma-synthase activity
J8Y18_21630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y18_21655	COG0768	penicillin binding
J8Y18_21675	COG0826	peptidase U32
J8Y18_21680	COG0826	peptidase U32
J8Y18_21685	COG4122	O-methyltransferase activity
J8Y18_21690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J8Y18_21720	COG0628	permease
J8Y18_21740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J8Y18_21755	COG1104	cysteine desulfurase activity
J8Y18_21760	COG1959	2 iron, 2 sulfur cluster binding
J8Y18_21765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J8Y18_21775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J8Y18_21800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8Y18_21810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J8Y18_21810	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J8Y18_21815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8Y18_21820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Y18_21820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Y18_21830	COG2244	polysaccharide biosynthetic process
J8Y18_21835	COG2323	membrane
J8Y18_21845	COG1862	Preprotein translocase
J8Y18_21875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J8Y18_21905	COG0157	Belongs to the NadC ModD family
J8Y18_21910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J8Y18_21915	COG1104	cysteine desulfurase activity
J8Y18_21920	COG1827	regulation of RNA biosynthetic process
J8Y18_21925	COG2258	MOSC domain
J8Y18_21930	COG0077	Prephenate dehydratase
J8Y18_21935	COG0577	efflux transmembrane transporter activity
J8Y18_21940	COG0577	efflux transmembrane transporter activity
J8Y18_21945	COG1136	(ABC) transporter
J8Y18_21950	COG5002	protein histidine kinase activity
J8Y18_21955	COG0745	RESPONSE REGULATOR receiver
J8Y18_21965	COG3290	protein histidine kinase activity
J8Y18_21975	COG2868	ribosomal protein
J8Y18_21985	COG1530	ribonuclease E activity
J8Y18_21990	COG1994	Peptidase M50
J8Y18_21995	COG0739	heme binding
J8Y18_22000	COG2894	cell division
J8Y18_22020	COG1077	Cell shape determining protein MreB Mrl
J8Y18_22040	COG0285	dihydrofolate synthase activity
J8Y18_22055	COG1388	LysM domain
J8Y18_22065	COG0113	porphobilinogen synthase activity
J8Y18_22070	COG1587	Uroporphyrinogen-III synthase
J8Y18_22080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Y18_22090	COG1846	Transcriptional regulator
J8Y18_22095	COG1764	response to oxidative stress
J8Y18_22110	COG1067	ATP-dependent peptidase activity
J8Y18_22110	COG0470	DNA polymerase III
J8Y18_22145	COG0457	Tetratricopeptide repeat
J8Y18_22210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J8Y18_22250	COG0622	Phosphoesterase
J8Y18_22265	COG5401	PFAM Sporulation and spore germination
J8Y18_22285	COG1309	transcriptional regulator
J8Y18_22295	COG2197	response regulator
J8Y18_22300	COG2233	PERMEase
J8Y18_22305	COG0402	S-adenosylhomocysteine deaminase activity
J8Y18_22310	COG1983	PspC domain protein
J8Y18_22315	COG1396	sequence-specific DNA binding
J8Y18_22320	COG0697	spore germination
J8Y18_22330	COG1959	2 iron, 2 sulfur cluster binding
J8Y18_22335	COG1668	transmembrane transport
J8Y18_22340	COG4152	abc transporter atp-binding protein
J8Y18_22345	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J8Y18_22350	COG1360	Flagellar Motor Protein
J8Y18_22355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Y18_22360	COG1876	peptidase activity
J8Y18_22365	COG0824	Thioesterase
J8Y18_22370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J8Y18_22375	COG1053	succinate dehydrogenase
J8Y18_22380	COG2009	succinate dehydrogenase
J8Y18_22385	COG1719	4-vinyl reductase, 4VR
J8Y18_22395	COG3118	belongs to the thioredoxin family
J8Y18_22400	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J8Y18_22405	COG2086	electron transfer activity
J8Y18_22410	COG1024	Enoyl-CoA hydratase
J8Y18_22415	COG1309	transcriptional regulator
J8Y18_22420	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y18_22445	COG2318	DinB family
J8Y18_22470	COG1131	(ABC) transporter
J8Y18_22475	COG2205	protein histidine kinase activity
J8Y18_22480	COG0745	RESPONSE REGULATOR receiver
J8Y18_22490	COG4895	conserved protein (DUF2196)
J8Y18_22495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8Y18_22505	COG4509	Sortase family
J8Y18_22510	COG1120	ATPase activity
J8Y18_22525	COG5386	Cell surface protein
J8Y18_22535	COG5386	Cell surface protein
J8Y18_22540	COG1114	Component of the transport system for branched-chain amino acids
J8Y18_22545	COG1187	pseudouridine synthase activity
J8Y18_22555	COG1796	DNA polymerase
J8Y18_22555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Y18_22560	COG1286	toxin biosynthetic process
J8Y18_22605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Y18_22615	COG1418	mRNA catabolic process
J8Y18_22635	COG2814	Major facilitator Superfamily
J8Y18_22640	COG1566	PFAM secretion protein HlyD family protein
J8Y18_22645	COG1309	transcriptional regulator
J8Y18_22650	COG1363	Peptidase, m42
J8Y18_22675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8Y18_22690	COG1484	DNA-dependent DNA replication
J8Y18_22695	COG3611	Membrane attachment protein
J8Y18_22705	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J8Y18_22710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Y18_22720	COG1971	Probably functions as a manganese efflux pump
J8Y18_22730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y18_22730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y18_22735	COG5002	protein histidine kinase activity
J8Y18_22740	COG0745	RESPONSE REGULATOR receiver
J8Y18_22760	COG0538	isocitrate dehydrogenase activity
J8Y18_22765	COG0372	Belongs to the citrate synthase family
J8Y18_22775	COG0628	permease
J8Y18_22780	COG3030	protein affecting phage T7 exclusion by the F plasmid
J8Y18_22805	COG1725	Transcriptional regulator
J8Y18_22810	COG0281	malic enzyme
J8Y18_22815	COG0587	DNA-directed DNA polymerase activity
J8Y18_22830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J8Y18_22845	COG4109	DRTGG domain
J8Y18_22860	COG0006	proline dipeptidase activity
J8Y18_22895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_22900	COG0662	Cupin 2, conserved barrel domain protein
J8Y18_22915	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y18_22920	COG0589	response to stress
J8Y18_22960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_22985	COG0827	DNA restriction-modification system
J8Y18_22990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J8Y18_22995	COG3874	Sporulation protein YtfJ
J8Y18_23010	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J8Y18_23020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y18_23035	COG1104	cysteine desulfurase activity
J8Y18_23045	COG0583	DNA-binding transcription factor activity
J8Y18_23050	COG0697	spore germination
J8Y18_23055	COG1309	transcriptional regulator
J8Y18_23060	COG1956	GAF domain-containing protein
J8Y18_23065	COG0626	cystathionine gamma-synthase activity
J8Y18_23090	COG0110	maltose O-acetyltransferase activity
J8Y18_23095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y18_23100	COG0454	-acetyltransferase
J8Y18_23105	COG0517	IMP dehydrogenase activity
J8Y18_23110	COG0123	including yeast histone deacetylase and acetoin utilization protein
J8Y18_23125	COG0745	RESPONSE REGULATOR receiver
J8Y18_23135	COG0666	response to abiotic stimulus
J8Y18_23170	COG1609	Transcriptional regulator
J8Y18_23175	COG1605	Chorismate mutase
J8Y18_23175	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J8Y18_23180	COG4851	CamS sex pheromone cAM373 precursor
J8Y18_23185	COG3118	belongs to the thioredoxin family
J8Y18_23195	COG2309	aminopeptidase activity
J8Y18_23210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_23215	COG0697	spore germination
J8Y18_23220	COG0789	Transcriptional regulator
J8Y18_23235	COG1674	ftsk spoiiie
J8Y18_23240	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y18_23240	COG1388	LysM domain
J8Y18_23250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y18_23260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y18_23265	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J8Y18_23270	COG1363	Peptidase, m42
J8Y18_23280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_23295	COG0510	thiamine kinase activity
J8Y18_23300	COG1523	belongs to the glycosyl hydrolase 13 family
J8Y18_23310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y18_23315	COG1349	DNA-binding transcription factor activity
J8Y18_23320	COG1187	pseudouridine synthase activity
J8Y18_23325	COG2244	polysaccharide biosynthetic process
J8Y18_23330	COG2081	HI0933 family
J8Y18_23335	COG2814	Major facilitator Superfamily
J8Y18_23345	COG3832	glyoxalase III activity
J8Y18_23365	COG1329	Transcriptional regulator
J8Y18_23390	COG0314	molybdopterin synthase activity
J8Y18_23395	COG1763	Mo-molybdopterin cofactor biosynthetic process
J8Y18_23400	COG0303	'Molybdopterin
J8Y18_23410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y18_23415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8Y18_23435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y18_23445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8Y18_23485	COG2814	Major facilitator Superfamily
J8Y18_23490	COG0475	glutathione-regulated potassium exporter activity
J8Y18_23495	COG0490	domain, Protein
J8Y18_23500	COG0582	viral genome integration into host DNA
J8Y18_23510	COG1136	(ABC) transporter
J8Y18_23530	COG1242	4 iron, 4 sulfur cluster binding
J8Y18_23535	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J8Y18_23540	COG1794	racemase activity, acting on amino acids and derivatives
J8Y18_23555	COG2267	carboxylic ester hydrolase activity
J8Y18_23560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J8Y18_23565	COG0671	phosphoesterase, PA-phosphatase related
J8Y18_23570	COG0438	transferase activity, transferring glycosyl groups
J8Y18_23590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_23640	COG5002	protein histidine kinase activity
J8Y18_23645	COG3852	Histidine kinase
J8Y18_23650	COG0753	catalase activity
J8Y18_23660	COG2267	carboxylic ester hydrolase activity
J8Y18_23665	COG1368	sulfuric ester hydrolase activity
J8Y18_23680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y18_23685	COG1116	anion transmembrane transporter activity
J8Y18_23690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y18_23715	COG0494	nUDIX hydrolase
J8Y18_23745	COG1854	S-ribosylhomocysteine lyase activity
J8Y18_23755	COG0288	reversible hydration of carbon dioxide
J8Y18_23765	COG1271	oxidase subunit
J8Y18_23770	COG1294	oxidase, subunit
J8Y18_23785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_23805	COG1842	Phage shock protein A
J8Y18_23835	COG5002	protein histidine kinase activity
J8Y18_23840	COG0745	RESPONSE REGULATOR receiver
J8Y18_23865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J8Y18_23870	COG1597	lipid kinase activity
J8Y18_23910	COG0586	Pfam SNARE associated Golgi protein
J8Y18_23920	COG0577	efflux transmembrane transporter activity
J8Y18_23925	COG1136	(ABC) transporter
J8Y18_23930	COG2207	Transcriptional regulator
J8Y18_23930	COG3708	Transcriptional regulator
J8Y18_23940	COG5658	integral membrane protein
J8Y18_23945	COG0640	Transcriptional regulator
J8Y18_23950	COG0745	RESPONSE REGULATOR receiver
J8Y18_23955	COG2205	protein histidine kinase activity
J8Y18_23960	COG0577	efflux transmembrane transporter activity
J8Y18_23965	COG0577	efflux transmembrane transporter activity
J8Y18_23970	COG1136	(ABC) transporter
J8Y18_23975	COG0577	efflux transmembrane transporter activity
J8Y18_24000	COG2188	Transcriptional regulator
J8Y18_24020	COG3964	amidohydrolase
J8Y18_24050	COG0745	RESPONSE REGULATOR receiver
J8Y18_24055	COG1136	(ABC) transporter
J8Y18_24060	COG0577	efflux transmembrane transporter activity
J8Y18_24065	COG4948	Mandelate Racemase Muconate Lactonizing
J8Y18_24075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J8Y18_24080	COG0596	Alpha beta hydrolase
J8Y18_24090	COG1169	isochorismate synthase
J8Y18_24095	COG1575	Belongs to the MenA family. Type 1 subfamily
J8Y18_24100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J8Y18_24125	COG0058	SHG alpha-glucan phosphorylase activity
J8Y18_24135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J8Y18_24155	COG1404	Belongs to the peptidase S8 family
J8Y18_24255	COG0544	peptidyl-prolyl cis-trans isomerase activity
J8Y18_24290	COG1285	pathogenesis
J8Y18_24295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Y18_24310	COG2155	Conserved Protein
J8Y18_24315	COG1098	S1 RNA binding domain
J8Y18_24320	COG0436	Aminotransferase
J8Y18_24325	COG1522	sequence-specific DNA binding
J8Y18_24330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Y18_24335	COG2267	carboxylic ester hydrolase activity
J8Y18_24345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J8Y18_24365	COG5018	Exonuclease
J8Y18_24370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y18_24390	COG2050	protein possibly involved in aromatic compounds catabolism
J8Y18_24400	COG1268	BioY protein
J8Y18_24410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J8Y18_24415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8Y18_24435	COG2076	Multidrug Resistance protein
J8Y18_24440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J8Y18_24450	COG3584	3D domain protein
J8Y18_24465	COG1252	NADH dehydrogenase
J8Y18_24480	COG3708	Transcriptional regulator
J8Y18_24495	COG1683	Conserved Protein
J8Y18_24525	COG0316	Belongs to the HesB IscA family
J8Y18_24540	COG1252	NADH dehydrogenase
J8Y18_24550	COG2274	protein secretion by the type I secretion system
J8Y18_24555	COG0390	transport system, permease component
J8Y18_24560	COG2824	Alkylphosphonate utilization operon protein PhnA
J8Y18_24605	COG4837	Protein of unknown function (DUF1462)
J8Y18_24610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J8Y18_24620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8Y18_24625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J8Y18_24645	COG1358	cellular component organization or biogenesis
J8Y18_24660	COG0577	efflux transmembrane transporter activity
J8Y18_24660	COG1136	(ABC) transporter
J8Y18_24665	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y18_24670	COG0647	UMP catabolic process
J8Y18_24680	COG2445	Protein of unknown function DUF86
J8Y18_24685	COG1494	fructose-1,6-bisphosphatase
J8Y18_24700	COG4470	Protein conserved in bacteria
J8Y18_24710	COG0789	Transcriptional regulator
J8Y18_24715	COG4377	Putative membrane peptidase family (DUF2324)
J8Y18_24740	COG0739	heme binding
J8Y18_24750	COG3377	Domain of unknown function (DUF1805)
J8Y18_24755	COG0737	Belongs to the 5'-nucleotidase family
J8Y18_24760	COG0719	Fe-S assembly protein
J8Y18_24765	COG0822	iron-sulfur transferase activity
J8Y18_24770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J8Y18_24775	COG0719	Fe-S assembly protein
J8Y18_24780	COG0396	ATPase activity
J8Y18_24785	COG1464	Belongs to the NlpA lipoprotein family
J8Y18_24790	COG1464	Belongs to the NlpA lipoprotein family
J8Y18_24795	COG2011	ABC-type metal ion transport system permease component
J8Y18_24810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y18_24815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J8Y18_24825	COG1393	Belongs to the ArsC family
J8Y18_24865	COG1309	transcriptional regulator
J8Y18_24870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y18_24875	COG1960	acyl-CoA dehydrogenase activity
J8Y18_24880	COG0183	Belongs to the thiolase family
J8Y18_24885	COG1024	Enoyl-CoA hydratase
J8Y18_24885	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8Y18_24895	COG1686	Belongs to the peptidase S11 family
J8Y18_24910	COG0011	TIGRFAM Protein of
J8Y18_24915	COG0840	transmembrane signaling receptor activity
J8Y18_24935	COG2814	Major facilitator Superfamily
J8Y18_24940	COG0531	amino acid
J8Y18_24965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y18_25000	COG0586	Pfam SNARE associated Golgi protein
J8Y18_25010	COG1376	ErfK ybiS ycfS ynhG family protein
J8Y18_25015	COG0745	RESPONSE REGULATOR receiver
J8Y18_25020	COG5002	protein histidine kinase activity
J8Y18_25050	COG0840	transmembrane signaling receptor activity
J8Y18_25055	COG2151	metal-sulfur cluster biosynthetic enzyme
J8Y18_25060	COG3227	Zinc metalloprotease (Elastase)
J8Y18_25080	COG0586	Pfam SNARE associated Golgi protein
J8Y18_25085	COG0475	glutathione-regulated potassium exporter activity
J8Y18_25090	COG0490	domain, Protein
J8Y18_25095	COG1115	amino acid carrier protein
J8Y18_25100	COG0783	Belongs to the Dps family
J8Y18_25120	COG1611	Belongs to the LOG family
J8Y18_25130	COG1528	Iron-storage protein
J8Y18_25140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_25145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_25150	COG1115	amino acid carrier protein
J8Y18_25155	COG1115	amino acid carrier protein
J8Y18_25160	COG2910	NAD(P)H-binding
J8Y18_25175	COG0656	L-ascorbic acid biosynthetic process
J8Y18_25180	COG2814	Major facilitator Superfamily
J8Y18_25185	COG1733	regulation of RNA biosynthetic process
J8Y18_25195	COG1252	NADH dehydrogenase
J8Y18_25200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J8Y18_25215	COG3290	protein histidine kinase activity
J8Y18_25215	COG0840	transmembrane signaling receptor activity
J8Y18_25250	COG0488	(ABC) transporter
J8Y18_25255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y18_25335	COG1309	transcriptional regulator
J8Y18_25350	COG0557	exoribonuclease II activity
J8Y18_25355	COG1647	Serine aminopeptidase, S33
J8Y18_25360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Y18_25365	COG1346	cytolysis
J8Y18_25400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Y18_25415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J8Y18_25425	COG1668	transmembrane transport
J8Y18_25430	COG4152	abc transporter atp-binding protein
J8Y18_25435	COG4585	Histidine kinase
J8Y18_25465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y18_25480	COG2323	membrane
J8Y18_25490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y18_25500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J8Y18_25510	COG1051	belongs to the nudix hydrolase family
J8Y18_25520	COG0492	ferredoxin-NADP+ reductase activity
J8Y18_25525	COG0457	Tetratricopeptide repeat
J8Y18_25530	COG0110	maltose O-acetyltransferase activity
J8Y18_25550	COG1950	PFAM Membrane protein of
J8Y18_25560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J8Y18_25565	COG0556	nucleotide-excision repair
J8Y18_25580	COG0789	Transcriptional regulator
J8Y18_25610	COG0583	DNA-binding transcription factor activity
J8Y18_25620	COG0655	NAD(P)H dehydrogenase (quinone) activity
J8Y18_25625	COG0488	(ABC) transporter
J8Y18_25635	COG1132	(ABC) transporter
J8Y18_25640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y18_25645	COG3409	Peptidoglycan-binding domain 1 protein
J8Y18_25645	COG0793	Belongs to the peptidase S41A family
J8Y18_25650	COG2177	Part of the ABC transporter FtsEX involved in
J8Y18_25655	COG2884	Cell division ATP-binding protein ftsE
J8Y18_25675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J8Y18_25680	COG1278	Cold shock
J8Y18_25685	COG1040	competence protein
J8Y18_25690	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J8Y18_25695	COG0791	NLP P60 protein
J8Y18_25700	COG1733	regulation of RNA biosynthetic process
J8Y18_25705	COG1307	EDD domain protein, DegV family
J8Y18_25710	COG1739	Uncharacterized protein family UPF0029
J8Y18_25715	COG1316	TRANSCRIPTIONal
J8Y18_25720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J8Y18_25725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J8Y18_25730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J8Y18_25740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J8Y18_25740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J8Y18_25760	COG1486	melibiose metabolic process
J8Y18_25765	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y18_25770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y18_25780	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y18_25790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y18_25795	COG1301	dicarboxylic acid transport
J8Y18_25810	COG1511	domain protein
J8Y18_25815	COG0583	DNA-binding transcription factor activity
J8Y18_25820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J8Y18_25830	COG1271	oxidase subunit
J8Y18_25835	COG1294	oxidase, subunit
J8Y18_25840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y18_25850	COG1620	l-lactate permease
J8Y18_25860	COG2389	metal-binding protein
J8Y18_25870	COG1368	sulfuric ester hydrolase activity
J8Y18_25880	COG0791	NLP P60 protein
J8Y18_25880	COG1388	LysM domain
J8Y18_25885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y18_25895	COG1215	transferase activity, transferring glycosyl groups
J8Y18_25900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y18_25905	COG3584	3D domain protein
J8Y18_25905	COG1388	LysM domain
J8Y18_25930	COG4715	Zinc finger, swim domain protein
J8Y18_25935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y18_25975	COG0577	efflux transmembrane transporter activity
J8Y18_25980	COG1136	(ABC) transporter
J8Y18_26000	COG2271	Major facilitator Superfamily
J8Y18_26015	COG5002	protein histidine kinase activity
J8Y18_26020	COG0745	RESPONSE REGULATOR receiver
J8Y18_26030	COG2244	polysaccharide biosynthetic process
J8Y18_26040	COG1316	TRANSCRIPTIONal
J8Y18_26050	COG1091	dTDP-4-dehydrorhamnose reductase activity
J8Y18_26065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J8Y18_26085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8Y18_26090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J8Y18_26095	COG4464	protein tyrosine phosphatase activity
J8Y18_26100	COG0489	protein tyrosine kinase activity
J8Y18_26105	COG3944	biosynthesis protein
J8Y18_26110	COG0489	protein tyrosine kinase activity
J8Y18_26125	COG1609	Transcriptional regulator
J8Y18_26135	COG0739	heme binding
J8Y18_26150	COG3279	Response regulator of the LytR AlgR family
J8Y18_26155	COG2385	sporulation resulting in formation of a cellular spore
J8Y18_26170	COG4836	Membrane
J8Y18_26175	COG1007	ATP synthesis coupled electron transport
J8Y18_26180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8Y18_26185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J8Y18_26195	COG0839	Belongs to the complex I subunit 6 family
J8Y18_26215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8Y18_26230	COG3300	MHYT domain
J8Y18_26230	COG5001	Diguanylate cyclase
J8Y18_26280	COG0356	it plays a direct role in the translocation of protons across the membrane
J8Y18_26315	COG0698	ribose 5-phosphate isomerase
J8Y18_26330	COG2259	Doxx family
J8Y18_26335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8Y18_26350	COG0009	L-threonylcarbamoyladenylate synthase
J8Y18_26385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J8Y18_26390	COG1494	fructose-1,6-bisphosphatase
J8Y18_26410	COG4821	SIS domain
J8Y18_26420	COG3343	RNA polymerase activity
J8Y18_26430	COG1960	acyl-CoA dehydrogenase activity
J8Y18_26435	COG1960	acyl-CoA dehydrogenase activity
J8Y18_26440	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8Y18_26445	COG0183	Belongs to the thiolase family
J8Y18_26450	COG0247	lactate metabolic process
J8Y18_26450	COG2181	nitrate reductase activity
J8Y18_26455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y18_26465	COG5001	Diguanylate cyclase
J8Y18_26465	COG3300	MHYT domain
J8Y18_26480	COG3227	Zinc metalloprotease (Elastase)
J8Y18_26485	COG2197	response regulator
J8Y18_26490	COG4585	Histidine kinase
J8Y18_26495	COG0842	Transport permease protein
J8Y18_26500	COG1131	(ABC) transporter
J8Y18_26505	COG0024	Methionine aminopeptidase
J8Y18_26515	COG2234	aminopeptidase activity
J8Y18_26535	COG1595	DNA-templated transcription, initiation
J8Y18_26545	COG4506	Protein conserved in bacteria
J8Y18_26550	COG1619	proteins homologs of microcin C7 resistance protein MccF
J8Y18_26575	COG2814	Major facilitator Superfamily
J8Y18_26580	COG0789	Transcriptional regulator
J8Y18_26585	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y18_26590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y18_26600	COG1994	Peptidase M50
J8Y18_26610	COG1078	dGTPase activity
J8Y18_26615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y18_26620	COG1120	ATPase activity
J8Y18_26625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_26630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y18_26650	COG0280	phosphate acetyltransferase
J8Y18_26665	COG3773	Cell wall hydrolase
J8Y18_26675	COG2363	Small membrane protein
J8Y18_26685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Y18_26690	COG2233	PERMEase
J8Y18_26695	COG0561	phosphatase activity
J8Y18_26700	COG2814	Major facilitator Superfamily
J8Y18_26710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J8Y18_26715	COG1131	(ABC) transporter
J8Y18_26720	COG2755	lipolytic protein G-D-S-L family
J8Y18_26725	COG1609	Transcriptional regulator
J8Y18_26735	COG0460	homoserine dehydrogenase
J8Y18_26745	COG2873	o-acetylhomoserine
J8Y18_26755	COG1011	Hydrolase
J8Y18_26760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Y18_26770	COG2197	response regulator
J8Y18_26775	COG2203	Gaf domain
J8Y18_26775	COG4585	Histidine kinase
J8Y18_26780	COG0351	phosphomethylpyrimidine kinase
J8Y18_26785	COG3706	GGDEF domain
J8Y18_26790	COG2879	small protein
J8Y18_26795	COG1966	Carbon starvation protein
J8Y18_26800	COG3279	Response regulator of the LytR AlgR family
J8Y18_26805	COG0477	Major facilitator Superfamily
J8Y18_26815	COG0438	transferase activity, transferring glycosyl groups
J8Y18_26830	COG0840	transmembrane signaling receptor activity
J8Y18_26840	COG1607	acyl-coa hydrolase
J8Y18_26845	COG1216	Glycosyl transferase, family 2
J8Y18_26855	COG1216	Glycosyl transferase, family 2
J8Y18_26865	COG4485	Bacterial membrane protein, YfhO
J8Y18_26870	COG0463	Glycosyl transferase, family 2
J8Y18_26875	COG0488	(ABC) transporter
J8Y18_26880	COG1309	transcriptional regulator
J8Y18_26885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Y18_26890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y18_26890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y18_26895	COG0628	permease
J8Y18_26915	COG3275	phosphorelay sensor kinase activity
J8Y18_26920	COG2814	Major facilitator Superfamily
J8Y18_26925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y18_26930	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J8Y18_26950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8Y18_26955	COG1272	protein, Hemolysin III
J8Y18_26975	COG1164	Oligoendopeptidase f
J8Y18_26985	COG5002	protein histidine kinase activity
J8Y18_27000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y18_27005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J8Y18_27010	COG4853	Protein conserved in bacteria
J8Y18_27020	COG5002	protein histidine kinase activity
J8Y18_27025	COG0745	RESPONSE REGULATOR receiver
J8Y18_27055	COG0305	Participates in initiation and elongation during chromosome replication
J8Y18_27065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J8Y18_27070	COG4241	membrane
J8Y18_27090	COG0012	GTP binding
J8Y18_27095	COG4481	Protein conserved in bacteria
J8Y18_27100	COG0668	transmembrane transport
J8Y18_27110	COG1475	DNA binding
J8Y18_27115	COG1192	Involved in chromosome partitioning
J8Y18_27140	COG1847	R3H domain protein
J8Y18_27145	COG0706	membrane insertase activity
J8Y18_27155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J8Y18_27160	COG0741	lytic transglycosylase activity
J8Y18_27160	COG0791	NLP P60 protein
J8Y18_27260	COG0551	DNA topoisomerase type I activity
J8Y18_27260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Y18_27310	COG4974	Belongs to the 'phage' integrase family
J8Y18_27340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J8Y18_27360	COG0270	DNA (cytosine-5-)-methyltransferase activity
J8Y18_27370	COG4166	transmembrane transport
J8Y18_27400	COG1192	Involved in chromosome partitioning
J8Y18_27660	COG1192	Involved in chromosome partitioning
J8Y18_27695	COG1396	sequence-specific DNA binding
J8Y18_27740	COG0305	Participates in initiation and elongation during chromosome replication
J8Y18_27790	COG0756	dUTP diphosphatase activity
J8Y18_27805	COG0270	DNA (cytosine-5-)-methyltransferase activity
J8Y18_27830	COG3728	DNA packaging
J8Y18_27830	COG5484	DNA packaging