locus-tag class description CK938_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CK938_00015 ENOG410848D S4 domain protein YaaA CK938_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CK938_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CK938_00100 ENOG4105ZMH deoxynucleoside kinase CK938_00110 ENOG4105GTG Isochorismatase CK938_00120 ENOG4108Z6B deaminase CK938_00130 ENOG4105C6E dna polymerase iii CK938_00150 ENOG41067KS pro-sigma K processing CK938_00185 ENOG4105CXN decarboxylase CK938_00195 ENOG4105FA2 dna polymerase iii CK938_00200 ENOG4105MA4 psp1 domain protein CK938_00210 ENOG41060K3 Methyltransferase CK938_00220 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CK938_00225 ENOG4105KRN Transcriptional regulator, abrb family CK938_00235 ENOG4105F8V Hydrolase, tatD family CK938_00240 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) CK938_00250 ENOG4105XFA sporulation peptidase YabG CK938_00255 ENOG4105W42 Veg protein CK938_00270 ENOG4105DFT pur operon repressor CK938_00280 ENOG4105KME endoribonuclease L-psp CK938_00295 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CK938_00310 ENOG4108JA2 transcriptioN-repair coupling factor CK938_00315 ENOG4108M14 stage v sporulation protein t CK938_00325 ENOG4108IY2 MazG family CK938_00330 ENOG41082I2 s4 domain protein CK938_00335 ENOG4105VYY sporulation protein yabp CK938_00350 ENOG41060GV RNA binding s1 domain protein CK938_00375 ENOG4108UGV hypoxanthine phosphoribosyltransferase CK938_00380 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CK938_00395 ENOG4105C6T cysteine synthase CK938_00400 ENOG4105CRQ synthase (Component I) CK938_00405 ENOG4105DDQ anthranilate synthase CK938_00410 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 CK938_00415 ENOG4105EEI dihydropteroate synthase CK938_00420 ENOG4105KRF dihydroneopterin aldolase CK938_00425 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CK938_00435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CK938_00525 ENOG4108Z0C Uvrb UvrC protein CK938_00540 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CK938_00550 ENOG4105CTP PilT protein domain protein CK938_00570 ENOG4105D7W serine acetyltransferase CK938_00585 ENOG4105C2N RNA methyltransferase TrmH family group 3 CK938_00590 ENOG4105M0M Tetracycline resistance protein CK938_00595 ENOG4105QIV RNA polymerase CK938_00610 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CK938_00635 ENOG4107Y49 methyltransferase CK938_00650 ENOG4105XPM ribosomal protein CK938_00760 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) CK938_00785 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CK938_00795 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CK938_00805 ENOG41067V7 50S ribosomal protein L36 CK938_00835 ENOG4108JJB ABC transporter CK938_00840 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) CK938_00870 ENOG4105D1F ATP-binding protein CK938_00885 ENOG4108NMV polysaccharide deacetylase CK938_00970 ENOG4105C8B TIGR00159 family CK938_00975 ENOG4107U5W ybbr family CK938_00995 ENOG4108VQT Alpha beta hydrolase fold protein CK938_01005 ENOG4105CMG Carbohydrate kinase CK938_01015 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CK938_01040 ENOG4108PSK reductase CK938_01045 ENOG4108UMI ABC transporter, permease CK938_01055 ENOG4105D01 (LipO)protein CK938_01060 ENOG4105EE1 crotonyl-CoA reductase CK938_01070 ENOG4105IQ5 FAD linked oxidase domain protein CK938_01085 ENOG4105C2C drug resistance transporter, Bcr CflA CK938_01105 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CK938_01110 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CK938_01115 ENOG4105C3U ABC transporter CK938_01120 ENOG4108JQ7 (ABC) transporter CK938_01150 ENOG4108J59 Extracellular solute-binding protein, family 5 CK938_01155 ENOG4108J59 Extracellular solute-binding protein, family 5 CK938_01165 ENOG4105II7 pyrroline-5-carboxylate reductase CK938_01175 ENOG4105E0C molybdate abc transporter CK938_01180 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CK938_01185 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family CK938_01225 ENOG4105F6E Acyl-transferase CK938_01245 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) CK938_01260 ENOG4108RE7 deoxyribonuclease CK938_01270 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) CK938_01295 ENOG4105C5H ABC transporter CK938_01300 ENOG4105BZU Histidine kinase CK938_01305 ENOG4105WH1 Two component transcriptional regulator luxr family CK938_01310 ENOG4105CJ1 ABC, transporter CK938_01315 ENOG41090VJ ABC-2 type transporter CK938_01320 ENOG4108KYE ABC-2 type transporter CK938_01335 ENOG4105DEF Extracellular solute-binding protein, family 5 CK938_01345 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CK938_01350 ENOG4105C3U ABC transporter CK938_01355 ENOG4108JQ7 (ABC) transporter CK938_01360 ENOG410667J hydrolase CK938_01395 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase CK938_01400 ENOG4105ERH Fumarylacetoacetate hydrolase CK938_01415 ENOG4105CUB amino acid CK938_01420 ENOG4108SC4 )-transporter CK938_01425 ENOG4105CPF Cell wall formation (By similarity) CK938_01430 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) CK938_01455 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein CK938_01460 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CK938_01470 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) CK938_01570 ENOG4105K8N protein family UPF0079, ATPase CK938_01575 ENOG41072GX Peptidase M22 Glycoprotease CK938_01580 ENOG410801F ribosomal-protein-alanine acetyltransferase CK938_01590 ENOG4105C5H ABC transporter CK938_01605 ENOG4108TYN CAAX amino terminal protease family protein CK938_01625 ENOG4105C7N Xanthine uracil vitamin C permease CK938_01635 ENOG4105BZU Histidine kinase CK938_01660 ENOG4107ZXU DSBA oxidoreductase CK938_01690 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CK938_01710 ENOG4108SHN Glycosyl transferase, family 2 CK938_01750 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_01775 ENOG4105SX7 Transporter CK938_01800 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CK938_01805 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CK938_01810 ENOG4105C83 adenylosuccinate lyase CK938_01820 ENOG4105VR9 phosphoribosylformylglycinamidine synthase CK938_01845 ENOG4108V3E phosphoribosylglycinamide formyltransferase CK938_01855 ENOG4105C12 Phosphoribosylglycinamide synthetase CK938_01885 ENOG4105C4R Atp-dependent dna helicase CK938_01915 ENOG4108W2Y isochorismatase CK938_01920 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CK938_01925 ENOG4108UMI ABC transporter, permease CK938_01930 ENOG4105D01 (LipO)protein CK938_01950 ENOG410834F Transcriptional regulator CK938_01955 ENOG4107I77 yiaA/B two helix domain CK938_01975 ENOG4105CBD Diacylglycerol kinase CK938_01980 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CK938_01985 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CK938_01990 ENOG4108JPW Aminotransferase CK938_02000 ENOG4105C26 Dehydrogenase CK938_02005 ENOG4105KPY Small multidrug resistance protein CK938_02025 ENOG4105D9N nucleoside CK938_02030 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CK938_02045 ENOG4105BZU Histidine kinase CK938_02050 ENOG4108W15 Protein of unknown function (DUF1456) CK938_02065 ENOG4105DTQ mandelate racemase muconate lactonizing CK938_02075 ENOG4105DFD Na H antiporter CK938_02095 ENOG4105D3R alkyl hydroperoxide reductase CK938_02100 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) CK938_02110 ENOG4107W7X Aldolase CK938_02115 ENOG4105EHG Permease protein CK938_02120 ENOG4105DQ5 transport system permease protein CK938_02125 ENOG4108V5C ABC transporter CK938_02155 ENOG4106UIA CK938_02160 ENOG4106UIA CK938_02195 ENOG410756H nucleotidyltransferase CK938_02200 ENOG4105D2S major facilitator superfamily CK938_02215 ENOG4107QJZ Glycosyl transferase, family 2 CK938_02225 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase CK938_02230 ENOG4105E5Q amino acid AbC transporter CK938_02235 ENOG4105EAB amino acid AbC transporter CK938_02250 ENOG4105C8Q Methyl-accepting chemotaxis CK938_02255 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CK938_02265 ENOG4105CI1 PTS System CK938_02305 ENOG4105CVR type I restriction-modification system CK938_02310 ENOG4105EKX Restriction modification system DNA (Specificity CK938_02315 ENOG4105DZR Type I site-specific deoxyribonuclease CK938_02365 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CK938_02380 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component CK938_02400 ENOG4105C5H ABC transporter CK938_02430 ENOG41062JF Transcriptional regulator CK938_02450 ENOG4105DEU major facilitator superfamily CK938_02480 ENOG4108N0M stress protein CK938_02485 ENOG4106FN3 tellurium resistance protein CK938_02490 ENOG4106FN3 tellurium resistance protein CK938_02495 ENOG4107TS3 membrane protein, TerC CK938_02500 ENOG4108TTB tellurium resistance protein CK938_02520 ENOG4105KJF protein tyrosine phosphatase CK938_02530 ENOG4107U9T Pfam:Ribonuclease_BN CK938_02540 ENOG4105C59 p-type ATPase CK938_02545 ENOG4108IPJ Membrane CK938_02555 ENOG4105C3F Signal peptidase i CK938_02565 ENOG4107ZTW SNARE associated Golgi CK938_02580 ENOG410606W general stress protein CK938_02585 ENOG4105UPD Calcium Proton CK938_02635 ENOG4108JUB Transcriptional regulator CK938_02645 ENOG4108IQI permease CK938_02680 ENOG4105CSV Glutaminase CK938_02690 ENOG4108A04 Beta-lactamase CK938_02705 ENOG4105CKK Glycosyl transferase, family 2 CK938_02710 ENOG4107QQG Dehydrogenase CK938_02715 ENOG4105C3I Nad-dependent epimerase dehydratase CK938_02720 ENOG4105CKK Glycosyl transferase, family 2 CK938_02735 ENOG4105F1A Pyruvate formate-lyase CK938_02755 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) CK938_02760 ENOG4105ECP epimerase CK938_02790 ENOG41067AE Membrane-bound metal-dependent hydrolase CK938_02795 ENOG4105CEN a g-specific adenine glycosylase CK938_02800 ENOG4106BXE CK938_02820 ENOG4105BZ1 (ABC) transporter CK938_02825 ENOG4107NBY Membrane CK938_02830 ENOG4105CBC glutamate synthase CK938_02840 ENOG4108IUW ABC transporter CK938_02860 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CK938_02865 ENOG4105G5W regulator Fur family CK938_03015 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CK938_03045 ENOG4108JQC penicillin-binding protein 1A CK938_03050 ENOG4107ZQN disulfide bond CK938_03060 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CK938_03070 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CK938_03075 ENOG4105BZU Histidine kinase CK938_03085 ENOG4105CYN Serine protein kinase CK938_03110 ENOG4105C94 Transporter CK938_03125 ENOG4105DZ6 Band 7 protein CK938_03135 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism CK938_03140 ENOG4108V9W transcriptional regulatory protein CK938_03145 ENOG4105D4T Citrate transporter CK938_03170 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator CK938_03175 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CK938_03180 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CK938_03185 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component CK938_03190 ENOG4105BZ7 extracellular solute-binding protein family 1 CK938_03195 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) CK938_03200 ENOG4108STX response regulator CK938_03205 ENOG4105US7 Histidine kinase CK938_03225 ENOG4108UZ3 Transporter CK938_03230 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CK938_03240 ENOG4105BZU Histidine kinase CK938_03245 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_03255 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) CK938_03260 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) CK938_03265 ENOG4108JB9 formate dehydrogenase CK938_03285 ENOG4105CUB amino acid CK938_03295 ENOG4105C59 p-type ATPase CK938_03300 ENOG4105DAP Nicotinate phosphoribosyltransferase CK938_03330 ENOG41073R8 VanW family CK938_03335 ENOG4108KGH TRANSCRIPTIONal CK938_03340 ENOG4105D9N nucleoside CK938_03345 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CK938_03350 ENOG4105C37 (CBS) domain CK938_03355 ENOG4108IJ0 Aspartate ammonia-lyase CK938_03360 ENOG4105DAA L-lactate CK938_03375 ENOG4105DUX Transporter CK938_03380 ENOG4108MES Periplasmic binding protein CK938_03385 ENOG4105DQ5 transport system permease protein CK938_03390 ENOG4108IHU transport system permease protein CK938_03395 ENOG4105E0A ABC, transporter CK938_03400 ENOG4105DMQ Methyltransferase CK938_03410 ENOG4105EXW epimerase dehydratase CK938_03415 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) CK938_03425 ENOG4107T89 von Willebrand factor, type A CK938_03430 ENOG4105GMT ATPase associated with various cellular activities aaa_5 CK938_03435 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CK938_03450 ENOG4105BZU Histidine kinase CK938_03455 ENOG4105D5Q Arginine ornithine antiporter CK938_03460 ENOG4107414 GntR family transcriptional regulator CK938_03465 ENOG4105C5Y PTS System CK938_03470 ENOG4105CG3 alpha amylase, catalytic region CK938_03485 ENOG4105E1K spore germination protein CK938_03490 ENOG4108XG2 Histidine kinase CK938_03495 ENOG4105WH1 Two component transcriptional regulator luxr family CK938_03500 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin CK938_03515 ENOG4105CRN Aminoglycoside phosphotransferase CK938_03520 ENOG4105BZG amino acid carrier protein CK938_03525 ENOG4105CDA abc transporter atp-binding protein CK938_03530 ENOG4105CT1 (ABC) transporter CK938_03535 ENOG4105EAD ABC transporter CK938_03540 ENOG4105DRP amino acid AbC transporter CK938_03545 ENOG4108IQI permease CK938_03560 ENOG4105GFR rna polymerase sigma factor CK938_03570 ENOG4105D29 Helix-turn-helix type 11 domain protein CK938_03575 ENOG4105NAE bifunctional deaminase-reductase domain protein CK938_03580 ENOG4105BZU Histidine kinase CK938_03595 ENOG4105CHH sulfate transporter CK938_03600 ENOG41068KF Universal stress protein CK938_03610 ENOG4105DEF Extracellular solute-binding protein, family 5 CK938_03620 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CK938_03625 ENOG4108JQ7 (ABC) transporter CK938_03635 ENOG4105CXY transporter CK938_03640 ENOG41067TZ transcriptional regulator, MarR family CK938_03645 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_03650 ENOG4105ETE Transcriptional regulator (LacI family CK938_03655 ENOG4108RVA ribokinase CK938_03665 ENOG4105C2J ABC transporter CK938_03670 ENOG4105CNN ABC, transporter CK938_03675 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CK938_03680 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CK938_03725 ENOG4105D7V transposase CK938_03760 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CK938_03765 ENOG41069ER domain protein CK938_03770 ENOG4105VZ8 Transcriptional regulator CK938_03775 ENOG4107D63 CK938_03790 ENOG4105DUX Transporter CK938_03810 ENOG4105C85 amino acid CK938_03815 ENOG4105C7N Xanthine uracil vitamin C permease CK938_03830 ENOG4105MA6 gCN5-related N-acetyltransferase CK938_03855 ENOG4105BZ9 Cytochrome C oxidase, subunit I CK938_03860 ENOG4105E2S oxidase) subunit II CK938_03880 ENOG4106CAD Protein of unknown function (DUF3311) CK938_03885 ENOG4105E1V na solute symporter CK938_03900 ENOG4108NHD germination protein CK938_03910 ENOG4105CE1 Ferrous iron transport protein b CK938_03915 ENOG4105CE1 Ferrous iron transport protein b CK938_03920 ENOG4105CE1 Ferrous iron transport protein b CK938_03925 ENOG4105CVA phosphate CK938_03930 ENOG4105C8U phosphate abc transporter CK938_03935 ENOG4105E2Z phosphate ABC transporter (Permease CK938_04065 ENOG41080XQ Signal transduction protein with cbs domains CK938_04090 ENOG4105ETU transcriptional activator (TenA CK938_04100 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CK938_04110 ENOG4108VEU Thiamine monophosphate synthase CK938_04115 ENOG41080HI glycine oxidase CK938_04130 ENOG4105D06 uba thif-type nad fad binding protein CK938_04135 ENOG4105DWF phosphomethylpyrimidine kinase CK938_04190 ENOG4108INS Transcriptional regulator CK938_04205 ENOG4105C7N Xanthine uracil vitamin C permease CK938_04215 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CK938_04230 ENOG4105K63 Thioredoxin CK938_04250 ENOG4108B31 Spore germination protein CK938_04270 ENOG4107Y03 Nitroreductase CK938_04305 ENOG4107SCJ type I restriction enzyme EcoKI subunit R CK938_04315 ENOG4107XZC Restriction modification system DNA (Specificity CK938_04325 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CK938_04330 ENOG4107Y5K Resolvase CK938_04375 ENOG4105ED1 spovr family CK938_04395 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase CK938_04400 ENOG4105XTG Pfam:DUF156 CK938_04410 ENOG4107TPS domain protein CK938_04415 ENOG4105VFE sira family CK938_04420 ENOG4105VFE sira family CK938_04430 ENOG4105VFE sira family CK938_04440 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase CK938_04445 ENOG41087NI Sulfite exporter TauE/SafE CK938_04455 ENOG4108KGH TRANSCRIPTIONal CK938_04485 ENOG4105EMD TRANSCRIPTIONal CK938_04490 ENOG4105VCP PTS System CK938_04495 ENOG4105VZJ PTS System CK938_04520 ENOG41069ER domain protein CK938_04535 ENOG4105XSJ toxin secretion phage lysis holin CK938_04545 ENOG4105K4H Nlp p60 protein CK938_04550 ENOG41069ER domain protein CK938_04555 ENOG4107RBB ABC transporter, permease CK938_04560 ENOG4105C19 ABC transporter CK938_04590 ENOG4105WEF catalase CK938_04625 ENOG4107T5V SNARE associated Golgi CK938_04660 ENOG4105CUB amino acid CK938_04665 ENOG4107RWR Sodium hydrogen exchanger CK938_04675 ENOG4106KNT transcriptional regulator CK938_04715 ENOG4108YXU transcriptional regulator AsnC family CK938_04725 ENOG4105KPY Small multidrug resistance protein CK938_04730 ENOG4105KPY Small multidrug resistance protein CK938_04750 ENOG41082F9 transcriptional regulator CK938_04755 ENOG41061H0 Monooxygenase CK938_04760 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_04775 ENOG4106A3M Cytochrome p-450 CK938_04800 ENOG4105NF4 modulator of drug activity CK938_04810 ENOG4105E5W Transporter CK938_04820 ENOG4107RKG DJ-1/PfpI family CK938_04825 ENOG4105CH6 catalase CK938_04835 ENOG4105D5Q Arginine ornithine antiporter CK938_04840 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) CK938_04850 ENOG4105C26 Dehydrogenase CK938_04870 ENOG4105BZ1 (ABC) transporter CK938_04875 ENOG4105BZ1 (ABC) transporter CK938_04890 ENOG4105DRP amino acid AbC transporter CK938_04895 ENOG4105CDA abc transporter atp-binding protein CK938_04910 ENOG410839P CK938_04945 ENOG4107FQX Alpha-acetolactate decarboxylase CK938_04965 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase CK938_04975 ENOG4105D4P Coproporphyrinogen iii oxidase CK938_04995 ENOG4105CHH sulfate transporter CK938_05030 ENOG4106AKK s-layer domain-containing protein CK938_05040 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CK938_05045 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CK938_05060 ENOG4105CGU Enoyl-CoA hydratase CK938_05080 ENOG4105DER m42 family CK938_05095 ENOG4108ZJ4 polysaccharide deacetylase CK938_05100 ENOG41086D8 Transcriptional regulator CK938_05110 ENOG4105G7B Protein of unknown function (DUF2992) CK938_05125 ENOG4108FPN Integrase CK938_05170 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CK938_05180 ENOG4108JQ7 (ABC) transporter CK938_05190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_05195 ENOG4105BZU Histidine kinase CK938_05240 ENOG4105CSH Transporter CK938_05250 ENOG4108MRH transcriptional regulatory protein CK938_05270 ENOG4107SCJ type I restriction enzyme EcoKI subunit R CK938_05295 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CK938_05300 ENOG4107RRE RNA-directed DNA polymerase CK938_05310 ENOG4105CDU Replicative dna helicase CK938_05335 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_05415 ENOG4105CID antiterminator CK938_05420 ENOG4105C5Y PTS System CK938_05425 ENOG4105CS2 ec 3.2.1.21 CK938_05435 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase CK938_05455 ENOG4105CMT Dihydroxyacetone kinase CK938_05465 ENOG4105CMT Dihydroxyacetone kinase CK938_05495 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase CK938_05580 ENOG4105WN5 stage II sporulation protein CK938_05590 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_05600 ENOG4108MJI response regulator CK938_05605 ENOG4105BZU Histidine kinase CK938_05610 ENOG4105BZU Histidine kinase CK938_05635 ENOG4105K8R UPF0145 protein CK938_05665 ENOG4105EQ0 Major Facilitator superfamily CK938_05690 ENOG4107VRP DNA repair exonuclease CK938_05695 ENOG4106D4I domain protein CK938_05735 ENOG4108MUZ hydrolase CK938_05750 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator CK938_05765 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CK938_05775 ENOG4105EMN RNA polymerase sigma factor CK938_05785 ENOG4105CNI cell division protein FtsW CK938_05800 ENOG4105C57 major facilitator superfamily CK938_05805 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_05815 ENOG4105EEM helicase CK938_05825 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CK938_05855 ENOG4105K59 histidine triad (HIT) protein CK938_05945 ENOG410905X membrane-flanked domain protein CK938_05950 ENOG4105CKV Membrane CK938_05980 ENOG410905X membrane-flanked domain protein CK938_05985 ENOG4105CKV Membrane CK938_05995 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation CK938_06000 ENOG4105BZ4 penicillin-binding protein CK938_06010 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) CK938_06015 ENOG4105C1Q protoporphyrinogen oxidase CK938_06045 ENOG4105ECB domain protein CK938_06065 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) CK938_06075 ENOG4105D29 Helix-turn-helix type 11 domain protein CK938_06085 ENOG4106AXD CK938_06090 ENOG4108RQ5 Beta-lactamase domain-containing protein CK938_06095 ENOG4105DF9 Lipoate-protein, ligase CK938_06110 ENOG4105CEY Amp-dependent synthetase and ligase CK938_06185 ENOG4105ENX hydrolase CK938_06190 ENOG4107RN3 metallophosphoesterase CK938_06195 ENOG4107TVP HD domain protein CK938_06205 ENOG4108AEY RNA polymerase sigma factor CK938_06215 ENOG41086D8 Transcriptional regulator CK938_06235 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_06260 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 CK938_06280 ENOG4105ZU5 s-layer protein CK938_06285 ENOG4107QP3 malate synthase g CK938_06300 ENOG4105VEQ Cold shock protein CK938_06315 ENOG4105XVF Competence transcription factor CK938_06320 ENOG4105BZU Histidine kinase CK938_06400 ENOG4105ERH Fumarylacetoacetate hydrolase CK938_06425 ENOG4105CAQ asparagine synthetase CK938_06430 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) CK938_06435 ENOG4105CH6 catalase CK938_06440 ENOG4105BZU Histidine kinase CK938_06470 ENOG4105QNR S1 RNA binding domain protein CK938_06475 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CK938_06485 ENOG4107AYK membrAne CK938_06490 ENOG41073B9 CK938_06500 ENOG4108KP7 hydrolase CK938_06515 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CK938_06545 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CK938_06550 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CK938_06570 ENOG4105C31 Tryptophanyl-tRNA synthetase CK938_06590 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CK938_06595 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CK938_06605 ENOG4108JQ7 (ABC) transporter CK938_06610 ENOG4105UQX Mate efflux family protein CK938_06635 ENOG4108ZCF integral membrane protein CK938_06645 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CK938_06655 ENOG4105DPN Oligoendopeptidase f CK938_06670 ENOG4108Z18 K06886 hemoglobin CK938_06675 ENOG4105MIX Adenylate cyclase CK938_06680 ENOG4106EFP UPF0738 protein CK938_06695 ENOG4105EMS pseudouridine synthase CK938_06715 ENOG4105K64 Glycosyl transferase, family 2 CK938_06735 ENOG4107TVC Glycosyl transferase, family 2 CK938_06755 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CK938_06760 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase CK938_06770 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase CK938_06845 ENOG4105CK7 Sodium proline symporter CK938_06855 ENOG4105CRQ synthase (Component I) CK938_06860 ENOG4105DDQ anthranilate synthase CK938_06965 ENOG4105C7S Dehydrogenase CK938_06975 ENOG4105VZ8 Transcriptional regulator CK938_07015 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) CK938_07030 ENOG4105DZ1 carboxypeptidase CK938_07035 ENOG4105VFR signal peptidase CK938_07070 ENOG4105C26 Dehydrogenase CK938_07080 ENOG4105F38 ABC transporter, permease CK938_07085 ENOG4105D38 putrescine abc transporter CK938_07090 ENOG4107RUE extracellular solute-binding protein family 1 CK938_07100 ENOG4105EYF MMPL domain protein CK938_07110 ENOG4108YBP pseudouridine synthase CK938_07120 ENOG4105K4I Scp-like extracellular CK938_07125 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CK938_07130 ENOG4105CQB FAD linked oxidase domain protein CK938_07145 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_07150 ENOG4105BZU Histidine kinase CK938_07155 ENOG4105JXH GntR family transcriptional regulator CK938_07175 ENOG4106A3R peptidase CK938_07185 ENOG4108QTI )-transporter CK938_07190 ENOG4107TS3 membrane protein, TerC CK938_07195 ENOG4105CZN Potassium uptake protein CK938_07200 ENOG410681C small acid-soluble spore protein CK938_07205 ENOG4108Z7G MaoC domain protein dehydratase CK938_07225 ENOG4105CHR reductase CK938_07260 ENOG4105C4Y ABC transporter CK938_07265 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CK938_07270 ENOG4107RCV ABC transporter, permease CK938_07290 ENOG4105E98 transcriptional regulator DeoR family CK938_07305 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) CK938_07315 ENOG4105PXI polysaccharide deacetylase CK938_07325 ENOG4105BZU Histidine kinase CK938_07330 ENOG41090MY MarR family Transcriptional regulator CK938_07340 ENOG4106DF1 CK938_07350 ENOG4105BZU Histidine kinase CK938_07360 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CK938_07365 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CK938_07410 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) CK938_07425 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CK938_07430 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family CK938_07435 ENOG4105CZV ABC transporter CK938_07445 ENOG4105CJ1 ABC, transporter CK938_07485 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CK938_07490 ENOG4105EA8 2-Nitropropane dioxygenase CK938_07495 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD CK938_07505 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein CK938_07530 ENOG4105NQC Flavodoxin CK938_07605 ENOG4105CZN Potassium uptake protein CK938_07610 ENOG41063Y9 CK938_07615 ENOG4105KBJ sporulation protein ytfj CK938_07645 ENOG4105CM2 brancheD-chain amino acid aminotransferase CK938_07650 ENOG4105C7K acetolactate synthase CK938_07655 ENOG4108ZP8 Acetolactate synthase small subunit CK938_07730 ENOG4107RVV histidinol phosphate phosphatase, hisj family CK938_07745 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase CK938_07750 ENOG4105E0M Sulfatase CK938_07760 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CK938_07780 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CK938_07785 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) CK938_07795 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CK938_07800 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein CK938_07805 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein CK938_07815 ENOG4105C8J )-transporter CK938_07835 ENOG4105DFD Na H antiporter CK938_07855 ENOG4105ENE Histidine kinase CK938_07860 ENOG4105WH1 Two component transcriptional regulator luxr family CK938_07880 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) CK938_07930 ENOG4105CJ3 phosphate transporter CK938_07935 ENOG4107GRR phosphate transport regulator CK938_07940 ENOG4105BZ4 penicillin-binding protein CK938_07955 ENOG4105BZU Histidine kinase CK938_07960 ENOG4105I3N Conserved Protein CK938_07975 ENOG4105BZU Histidine kinase CK938_08005 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CK938_08010 ENOG4105DZ1 carboxypeptidase CK938_08015 ENOG4108JIC nucleoside recognition domain protein CK938_08025 ENOG4105FE9 pseudouridine synthase CK938_08035 ENOG4107TWT Cytochrome c biogenesis protein CK938_08040 ENOG4105CRE cytochrome C CK938_08045 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_08050 ENOG4105BZU Histidine kinase CK938_08055 ENOG4108WBT adenosyltransferase CK938_08060 ENOG41063SB peptidase CK938_08080 ENOG4108SAX Membrane CK938_08095 ENOG4105C9U ATP-dependent DNA helicase RecQ CK938_08100 ENOG4105I7S Abortive infection protein CK938_08110 ENOG4107RGJ metallophosphoesterase CK938_08115 ENOG4107X2D transcriptional regulator, merr family CK938_08120 ENOG4108S6Z Negative regulator of genetic competence CK938_08145 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase CK938_08150 ENOG4105HDK L-asparaginase CK938_08185 ENOG4105S2F CK938_08190 ENOG41065D1 CK938_08220 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) CK938_08235 ENOG4105XXQ heptaprenyl diphosphate synthase component I CK938_08245 ENOG4105EAH synthase CK938_08265 ENOG4105CIH Imidazole acetol-phosphate transaminase CK938_08270 ENOG41068YB TPR repeat-containing protein CK938_08285 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) CK938_08290 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) CK938_08330 ENOG4108JYZ YitT family CK938_08340 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase CK938_08355 ENOG4105FJR Lmbe family CK938_08360 ENOG4105CPK Glycosyl transferase (Group 1 CK938_08400 ENOG4105DVT helicase CK938_08405 ENOG4105YAC CK938_08425 ENOG4105CSM endonuclease III CK938_08435 ENOG4105BZ4 penicillin-binding protein CK938_08495 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) CK938_08505 ENOG4105DVT helicase CK938_08510 ENOG4105CTD carboxy-peptidase CK938_08520 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CK938_08530 ENOG4105C2W permease CK938_08535 ENOG4105DHF Membrane CK938_08545 ENOG410890F Dynamin family CK938_08555 ENOG4108W0I acetyltransferase CK938_08565 ENOG4105KHC sulfurtransferase CK938_08590 ENOG4106032 Glutathionylspermidine synthase CK938_08630 ENOG4108W2Y isochorismatase CK938_08695 ENOG4105DA5 (ABC) transporter CK938_08720 ENOG4107QHE Choloylglycine hydrolase CK938_08730 ENOG410890F Dynamin family CK938_08735 ENOG4105E0M Sulfatase CK938_08750 ENOG4105F0V Cell wall hydrolase CK938_08795 ENOG4105BZU Histidine kinase CK938_08825 ENOG4105D03 DNA-3-methyladenine glycosylase II CK938_08830 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CK938_08860 ENOG4105E0A ABC, transporter CK938_08865 ENOG4105NIV Esterase CK938_08885 ENOG4105PGM cation diffusion facilitator family transporter CK938_08895 ENOG4105VPX protein, conserved in bacteria CK938_08900 ENOG410681U heavy metal transport detoxification protein CK938_08905 ENOG4105C59 p-type ATPase CK938_08915 ENOG4105K70 DNA-binding protein CK938_08920 ENOG4105TMB Formate nitrite transporter CK938_08945 ENOG4105C85 amino acid CK938_08960 ENOG4108SJC Membrane CK938_08965 ENOG4107QW4 alcohol dehydrogenase CK938_08970 ENOG4105E98 transcriptional regulator DeoR family CK938_08975 ENOG4105DE4 1-phosphofructokinase CK938_08980 ENOG4105DM4 PTS System CK938_08985 ENOG41069ER domain protein CK938_09020 ENOG4106F1P AAA ATPase, central domain protein CK938_09025 ENOG4105EN6 Membrane CK938_09030 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CK938_09035 ENOG4105CXI aluminum resistance protein CK938_09040 ENOG4105KV4 Transcriptional regulator CK938_09045 ENOG4105C5F glutamine synthetase CK938_09050 ENOG4105HTX biosynthesis protein CK938_09055 ENOG4107YJ4 chain length determinant protein CK938_09065 ENOG4108PQP glycosyl transferase group 1 CK938_09070 ENOG4108KMV Glycosyl transferase (Group 1 CK938_09075 ENOG4107SJB teichoic acid biosynthesis CK938_09080 ENOG41068W6 Capsular polysaccharide biosynthesis protein CK938_09085 ENOG4108KMV Glycosyl transferase (Group 1 CK938_09095 ENOG4105CG5 Glycosyl transferase (Group 1 CK938_09125 ENOG4105D3Q Sugar transferase CK938_09130 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family CK938_09135 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CK938_09140 ENOG4105CAQ asparagine synthetase CK938_09165 ENOG4105BZ1 (ABC) transporter CK938_09170 ENOG4105K7K Transcriptional regulator CK938_09190 ENOG4108SVB resolvase CK938_09200 ENOG4105CGH 5'-nucleotidase CK938_09205 ENOG4108HW3 (ABC) transporter CK938_09210 ENOG4105D5T phosphonate abc transporter CK938_09245 ENOG4105BZ1 (ABC) transporter CK938_09250 ENOG4105BZ1 (ABC) transporter CK938_09270 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase CK938_09295 ENOG41067MG lrgb family CK938_09305 ENOG4107RSM transcriptional regulator CK938_09315 ENOG4105CJ1 ABC, transporter CK938_09325 ENOG4105CH2 amidohydrolase CK938_09340 ENOG4107QIV Cytochrome c biogenesis protein CK938_09390 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) CK938_09415 ENOG4108903 Formimidoylglutamase CK938_09420 ENOG4108VJ1 Transcriptional regulator (CarD family CK938_09425 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CK938_09430 ENOG4105CBC glutamate synthase CK938_09440 ENOG4105CK7 Sodium proline symporter CK938_09445 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase CK938_09450 ENOG4105FBA Phospholipase Carboxylesterase CK938_09455 ENOG4105BZU Histidine kinase CK938_09470 ENOG4107AYK membrAne CK938_09520 ENOG4108IMY Transcriptional regulator CK938_09535 ENOG4105CEY Amp-dependent synthetase and ligase CK938_09540 ENOG4107ZYJ bioY protein CK938_09545 ENOG4107F3J Amp-dependent synthetase and ligase CK938_09565 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CK938_09575 ENOG4105E5W Transporter CK938_09605 ENOG4108I0Z Aconitate hydratase CK938_09615 ENOG4108JJ8 (ABC) transporter CK938_09625 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CK938_09635 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) CK938_09660 ENOG4105W8X HesB YadR YfhF-family protein CK938_09670 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CK938_09680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_09685 ENOG4105C0H protease CK938_09690 ENOG4105K4P CoA-binding domain protein CK938_09700 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CK938_09720 ENOG4105D9R oxidoreductase CK938_09730 ENOG4105CIG ABC transporter CK938_09745 ENOG4105EMN RNA polymerase sigma factor CK938_09755 ENOG4108KGH TRANSCRIPTIONal CK938_09760 ENOG4107QJT sodium dicarboxylate symporter CK938_09825 ENOG4105E1K spore germination protein CK938_09835 ENOG4108JB9 formate dehydrogenase CK938_09845 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) CK938_09850 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) CK938_09865 ENOG4105TMB Formate nitrite transporter CK938_09870 ENOG4105D06 uba thif-type nad fad binding protein CK938_09875 ENOG4105CVM Molybdenum cofactor synthesis domain protein CK938_09880 ENOG4108ZAF Molybdopterin CK938_09890 ENOG4105D1F ATP-binding protein CK938_09905 ENOG410696E Membrane CK938_09910 ENOG4105FR1 rard protein CK938_09920 ENOG4105EWU Squalene--hopene cyclase CK938_09930 ENOG4105CHR reductase CK938_09935 ENOG4105C26 Dehydrogenase CK938_09945 ENOG4108IA2 Sodium pantothenate symporter CK938_09960 ENOG4106IQC argininosuccinate lyase CK938_09970 ENOG410904N short-chain dehydrogenase reductase CK938_09990 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) CK938_10010 ENOG4105VEQ Cold shock protein CK938_10030 ENOG4108R1P CK938_10040 ENOG41073R8 VanW family CK938_10045 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase CK938_10060 ENOG4105KT7 mgtC SapB transporter CK938_10095 ENOG4105CQB FAD linked oxidase domain protein CK938_10100 ENOG4105C09 Bile acid CK938_10110 ENOG4105RHY Pfam:UPF0157 CK938_10140 ENOG4105BZ1 (ABC) transporter CK938_10155 ENOG4107JM4 Tetratricopeptide repeat CK938_10165 ENOG4105CIS alcohol dehydrogenase CK938_10170 ENOG41082BM Transcriptional regulator, arsr family CK938_10190 ENOG4107VXM glycerophosphoryl diester phosphodiesterase CK938_10220 ENOG4108A04 Beta-lactamase CK938_10225 ENOG4105DPN Oligoendopeptidase f CK938_10230 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase CK938_10235 ENOG4105C98 muts2 protein CK938_10250 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CK938_10260 ENOG4107V2S Transcriptional regulator CK938_10270 ENOG4107CUJ Protein of unknown function (DUF2690) CK938_10295 ENOG4105NX3 Membrane CK938_10300 ENOG4105DQ5 transport system permease protein CK938_10305 ENOG4105EHG Permease protein CK938_10310 ENOG4108MES Periplasmic binding protein CK938_10325 ENOG4107R3E Citrate transporter CK938_10335 ENOG4108TN2 lmbE family CK938_10370 ENOG4105CIS alcohol dehydrogenase CK938_10375 ENOG4105K7K Transcriptional regulator CK938_10420 ENOG4105H3G oxidoreductase CK938_10440 ENOG410751J CK938_10465 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) CK938_10545 ENOG4108ZJ4 polysaccharide deacetylase CK938_10565 ENOG4105KVH Transcriptional regulator CK938_10570 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein CK938_10580 ENOG4105KNA -acetyltransferase CK938_10590 ENOG4105CHR reductase CK938_10600 ENOG4105JAB phenazine biosynthesis protein, phzf family CK938_10640 ENOG4105KVH Transcriptional regulator CK938_10645 ENOG4105KVH Transcriptional regulator CK938_10650 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CK938_10655 ENOG4105D9R oxidoreductase CK938_10660 ENOG4108TZY GntR Family Transcriptional Regulator CK938_10665 ENOG4105KVH Transcriptional regulator CK938_10700 ENOG4105C44 Serine transporter CK938_10705 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) CK938_10725 ENOG4105F27 Major Facilitator CK938_10730 ENOG4105CV8 reductase CK938_10750 ENOG4107EXU Short-chain dehydrogenase reductase Sdr CK938_10765 ENOG4107EXU Short-chain dehydrogenase reductase Sdr CK938_10780 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) CK938_10785 ENOG4105KVH Transcriptional regulator CK938_10790 ENOG4105EWI Short-chain dehydrogenase reductase Sdr CK938_10810 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone CK938_10815 ENOG4105CIS alcohol dehydrogenase CK938_10820 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CK938_10825 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CK938_10840 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CK938_10845 ENOG4105C6Z Gluconate CK938_10850 ENOG4105CMG Carbohydrate kinase CK938_10855 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) CK938_10865 ENOG4105XDF Protein of unknown function (DUF1272) CK938_10875 ENOG4105C5Q Transcriptional regulator CK938_10880 ENOG4105DDN Pentapeptide repeat-containing protein CK938_10910 ENOG4105FAW cDP-glucose 4,6-dehydratase CK938_10915 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase CK938_10930 ENOG4105C37 (CBS) domain CK938_10955 ENOG4105EV4 Multidrug resistance protein mdtH CK938_10965 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) CK938_10995 ENOG4105C31 Tryptophanyl-tRNA synthetase CK938_11000 ENOG4108UW5 maltose o-acetyltransferase CK938_11005 ENOG4105DKQ ROK family CK938_11010 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase CK938_11065 ENOG4105CJ1 ABC, transporter CK938_11075 ENOG4108PSK reductase CK938_11100 ENOG4108RCM Nitroreductase CK938_11120 ENOG4105KVH Transcriptional regulator CK938_11135 ENOG4108Z66 YbaK ebsC protein CK938_11160 ENOG4107TXC Transcriptional regulator CK938_11165 ENOG4108IND Tetr family transcriptional regulator CK938_11170 ENOG4105EQ0 Major Facilitator superfamily CK938_11200 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) CK938_11235 ENOG4105DYS nad(p)h dehydrogenase (quinone) CK938_11245 ENOG4105CRW Short chain fatty acid transporter CK938_11265 ENOG4105KBX Transcriptional regulator, TetR family CK938_11270 ENOG4105KPY Small multidrug resistance protein CK938_11275 ENOG4105RXJ CK938_11285 ENOG41069JR CK938_11290 ENOG4105DA5 (ABC) transporter CK938_11310 ENOG4105CZM Major Facilitator CK938_11315 ENOG4107MII Sugar-specific transcriptional regulator TrmB CK938_11330 ENOG4108ISG Major Facilitator CK938_11360 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase CK938_11385 ENOG410874W AraC family transcriptional regulator CK938_11395 ENOG41082W1 Cupin 2, conserved barrel domain protein CK938_11415 ENOG4108JQ1 Dehydrogenase CK938_11430 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A CK938_11445 ENOG4106P55 Transcriptional regulator CK938_11455 ENOG4107QR9 Iron-sulfur cluster binding protein CK938_11460 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) CK938_11465 ENOG4105DJB Major Facilitator Superfamily CK938_11470 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) CK938_11480 ENOG4105BZU Histidine kinase CK938_11505 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) CK938_11525 ENOG4105JQZ Methyltransferase CK938_11565 ENOG4105K6H D-cysteine desulfhydrase CK938_11615 ENOG4105IIP Membrane CK938_11635 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_11640 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) CK938_11675 ENOG4105ED2 Beta-lactamase CK938_11695 ENOG4105D7V transposase CK938_11710 ENOG4108YXU transcriptional regulator AsnC family CK938_11715 ENOG4105CHR reductase CK938_11750 ENOG4108JGH Tetr family transcriptional regulator CK938_11755 ENOG4105EQ0 Major Facilitator superfamily CK938_11770 ENOG4108IG5 Transcriptional regulator CK938_11775 ENOG4107P5I polyketide synthase CK938_11785 ENOG4105NAE bifunctional deaminase-reductase domain protein CK938_11800 ENOG41085FC arsR family transcriptional regulator CK938_11805 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase CK938_11810 ENOG4105D6J arsenicaL-resistance protein CK938_11820 ENOG4105ETE Transcriptional regulator (LacI family CK938_11825 ENOG4105NWF RbsD or FucU transport CK938_11835 ENOG4105CNN ABC, transporter CK938_11845 ENOG4107W7X Aldolase CK938_11850 ENOG4105DET Rhamnulokinase CK938_11870 ENOG4105Z7P Acetyltransferase (GNAT) family CK938_11895 ENOG4108NEV two component transcriptional regulator, LytTR family CK938_11910 ENOG4105C19 ABC transporter CK938_11920 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) CK938_11925 ENOG4105D7V transposase CK938_11930 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CK938_11940 ENOG4105E1K spore germination protein CK938_11960 ENOG4105GPN Uncharacterized conserved protein (DUF2294) CK938_11965 ENOG4108TWJ NADH dehydrogenase subunit 5 CK938_11980 ENOG4105CVP deoxyribo-dipyrimidine photolyase CK938_11985 ENOG4108606 TspO/MBR family CK938_12035 ENOG4105CH6 catalase CK938_12040 ENOG4105CGH 5'-nucleotidase CK938_12045 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CK938_12055 ENOG4105E2A Dehydrogenase CK938_12085 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CK938_12105 ENOG4105DWD nucleoside recognition domain protein CK938_12120 ENOG4105FDT acyl-CoA dehydrogenase CK938_12135 ENOG4108ZHR arsR family transcriptional regulator CK938_12140 ENOG4108ZRV stage ii sporulation protein p CK938_12145 ENOG4106N3A copper homeostasis protein cutc CK938_12155 ENOG4107258 Transcriptional regulator CK938_12160 ENOG4105P4J Allophanate hydrolase, subunit 1 CK938_12200 ENOG4107RF6 penicillin-binding protein CK938_12240 ENOG4105F1N DNA alkylation repair CK938_12250 ENOG4108IQI permease CK938_12255 ENOG4105KNA -acetyltransferase CK938_12260 ENOG410635A Membrane CK938_12325 ENOG4108XET gCN5-related N-acetyltransferase CK938_12330 ENOG4108DMH HTH_ARAC CK938_12355 ENOG4105C19 ABC transporter CK938_12370 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) CK938_12390 ENOG4105FS7 Transcriptional regulator CK938_12395 ENOG4108TVJ Nitroreductase CK938_12460 ENOG4105C8Y Acetylornithine aminotransferase CK938_12480 ENOG4105C7R Atpase associated with various cellular activities aaa_3 CK938_12505 ENOG4105KNA -acetyltransferase CK938_12525 ENOG4108WCX response regulator CK938_12535 ENOG41090T1 Membrane CK938_12550 ENOG4105VMP Transcriptional regulator CK938_12560 ENOG4105G6Z alkaline phosphatase CK938_12570 ENOG4105ECK Fatty Acid Desaturase CK938_12575 ENOG4105E0Y RtcB Protein CK938_12590 ENOG4107258 Transcriptional regulator CK938_12600 ENOG4105II7 pyrroline-5-carboxylate reductase CK938_12635 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) CK938_12650 ENOG41061GT Aldolase CK938_12660 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) CK938_12665 ENOG4105DKT Transcriptional regulator CK938_12685 ENOG4105D4B ABC, transporter CK938_12710 ENOG41069ER domain protein CK938_12755 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase CK938_12770 ENOG4105CIH Imidazole acetol-phosphate transaminase CK938_12790 ENOG41082JN Transcriptional regulator CK938_12795 ENOG4105EYF MMPL domain protein CK938_12810 ENOG4105C5H ABC transporter CK938_12820 ENOG4105E0M Sulfatase CK938_12825 ENOG4108ZCF integral membrane protein CK938_12830 ENOG4106ETB IIa component CK938_12840 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CK938_12850 ENOG4107VMI polysaccharide deacetylase CK938_12855 ENOG4107VC0 DNA alkylation repair enzyme CK938_12900 ENOG4108AQF aminoglycoside N(3)-acetyltransferase CK938_12945 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein CK938_12950 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CK938_12955 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) CK938_12970 ENOG4105C02 permease CK938_13025 ENOG4105DVE abc transporter atp-binding protein CK938_13040 ENOG4108ZMI UPF0477 protein CK938_13055 ENOG4105CHM Aminotransferase CK938_13095 ENOG41089UC methyltransferase, type 11 CK938_13110 ENOG4107BMA Transglycosylase associated protein CK938_13130 ENOG4106K7D Major facilitator family transporter CK938_13135 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) CK938_13200 ENOG4105EPR degv family CK938_13240 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_13245 ENOG4105BZU Histidine kinase CK938_13250 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CK938_13255 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) CK938_13310 ENOG4105DTQ mandelate racemase muconate lactonizing CK938_13325 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) CK938_13330 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD CK938_13345 ENOG4107T5V SNARE associated Golgi CK938_13350 ENOG4105DCI Phosphohydrolase CK938_13390 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein CK938_13400 ENOG41080HI glycine oxidase CK938_13405 ENOG4105CTU Proline racemase CK938_13410 ENOG4105CTU Proline racemase CK938_13415 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CK938_13420 ENOG4105C26 Dehydrogenase CK938_13425 ENOG4105BZG amino acid carrier protein CK938_13445 ENOG4108M1A Chitin-binding protein CK938_13500 ENOG4105C9U ATP-dependent DNA helicase RecQ CK938_13525 ENOG4105EEM helicase CK938_13545 ENOG4108Z7F N-acetyltransferase CK938_13570 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 CK938_13580 ENOG4105MSB protein, conserved in bacteria CK938_13585 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CK938_13610 ENOG41087PP glycosyltransferase MGT family CK938_13615 ENOG4108M1A Chitin-binding protein CK938_13620 ENOG41082BV acetyltransferase CK938_13625 ENOG4105E66 phosphoriboisomerase A CK938_13650 ENOG4108IJ7 Glycine betaine CK938_13655 ENOG4107SQ8 Glycine betaine CK938_13680 ENOG4108TIT dATP pyrophosphohydrolase CK938_13690 ENOG4105RHY Pfam:UPF0157 CK938_13695 ENOG4105E1F short-chain dehydrogenase reductase CK938_13705 ENOG4107RUY (E1 component), alpha subunit CK938_13715 ENOG4107QKR Dehydrogenase CK938_13740 ENOG4105E98 transcriptional regulator DeoR family CK938_13760 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family CK938_13795 ENOG4107Z3H Transcriptional regulator, TetR family CK938_13830 ENOG4105MSI germination protein ypeb CK938_13885 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CK938_13900 ENOG4108IUM Glycogen debranching enzyme CK938_13925 ENOG4105U0R haloacid dehalogenase-like hydrolase CK938_13950 ENOG4107VFR oxidoreductase CK938_13990 ENOG4105PKS Excinuclease abc c subunit domain protein CK938_14025 ENOG4105KWG Pfam:DUF1696 CK938_14030 ENOG4108NRW Phospholipase, patatin family CK938_14050 ENOG4108XI2 Domain of unknown function (DUF1963) CK938_14095 ENOG41086D8 Transcriptional regulator CK938_14115 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CK938_14120 ENOG4105E09 nadh pyrophosphatase CK938_14135 ENOG4105FCD Major Facilitator CK938_14160 ENOG4105EGD dinuclear metal center protein, YbgI family CK938_14170 ENOG4107Y9U Membrane CK938_14190 ENOG4107VXM glycerophosphoryl diester phosphodiesterase CK938_14230 ENOG4108WC5 Alpha Beta Hydrolase Fold protein CK938_14235 ENOG41087PP glycosyltransferase MGT family CK938_14240 ENOG4105CVK Glutamate decarboxylase CK938_14245 ENOG4108V4B ThiJ pfpI CK938_14290 ENOG4105CHR reductase CK938_14295 ENOG4108IG5 Transcriptional regulator CK938_14300 ENOG4105CJN penicillin-binding protein CK938_14305 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CK938_14310 ENOG4105CB2 alcohol dehydrogenase CK938_14315 ENOG4105RHY Pfam:UPF0157 CK938_14325 ENOG4108HGU Histidine kinase CK938_14360 ENOG4107RF6 penicillin-binding protein CK938_14365 ENOG4105BZU Histidine kinase CK938_14375 ENOG410667J hydrolase CK938_14510 ENOG4108TFU terminase (Small subunit) CK938_14515 ENOG4108TFU terminase (Small subunit) CK938_14580 ENOG4105ETU transcriptional activator (TenA CK938_14600 ENOG4105D6E homoserine dehydrogenase CK938_14615 ENOG4105DK7 lysyl-tRNA synthetase CK938_14635 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CK938_14640 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) CK938_14645 ENOG410900G Protein of unknown function (DUF421) CK938_14665 ENOG4105EFA 4-hydroxyphenylacetate CK938_14690 ENOG4105CUV Homoserine Kinase CK938_14705 ENOG41089UC methyltransferase, type 11 CK938_14715 ENOG4107Y80 Major Facilitator superfamily CK938_14725 ENOG4105FQP Beta-lactamase CK938_14770 ENOG4108RYK Nad-dependent epimerase dehydratase CK938_14775 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) CK938_14790 ENOG4105T9C HD domain CK938_14810 ENOG4105DBI uridine monophosphokinase CK938_14835 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CK938_14840 ENOG4107QX3 carboxylase CK938_14845 ENOG4105E39 Enoyl-CoA hydratase CK938_14850 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase CK938_14855 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit CK938_14860 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CK938_14865 ENOG4105C1G acyl-Coa dehydrogenase CK938_14885 ENOG4107Z3H Transcriptional regulator, TetR family CK938_14895 ENOG4105CJ1 ABC, transporter CK938_14905 ENOG4107RGJ metallophosphoesterase CK938_14915 ENOG4107RF6 penicillin-binding protein CK938_14920 ENOG4107RF6 penicillin-binding protein CK938_14950 ENOG4105CIN aminoacyl-histidine dipeptidase CK938_15010 ENOG4107RA9 decarboxylase CK938_15020 ENOG41088CC tellurite resistance protein tehB CK938_15040 ENOG4108RZE Tetr family transcriptional regulator CK938_15065 ENOG4105C1J atp-dependent rna helicase CK938_15080 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) CK938_15160 ENOG4105D9P serine threonine protein kinase CK938_15180 ENOG4105C7B Threonine dehydratase CK938_15195 ENOG4105RD7 BadF BadG BcrA BcrD CK938_15220 ENOG4105F32 YngK protein CK938_15250 ENOG4108KPJ rna polymerase sigma factor CK938_15295 ENOG4108JCI Transcriptional regulator CK938_15310 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) CK938_15315 ENOG4107STQ Multicopper oxidase CK938_15370 ENOG4105BZ1 (ABC) transporter CK938_15375 ENOG4105BZ1 (ABC) transporter CK938_15390 ENOG4108RPX mosc domain containing protein CK938_15395 ENOG4105DND Transcriptional regulator CK938_15410 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CK938_15415 ENOG4107V2S Transcriptional regulator CK938_15435 ENOG410667J hydrolase CK938_15455 ENOG4105VEQ Cold shock protein CK938_15465 ENOG41068WN CK938_15475 ENOG4105C1Q protoporphyrinogen oxidase CK938_15500 ENOG4105WCN acetyltransferase CK938_15520 ENOG4105EYF MMPL domain protein CK938_15530 ENOG4105C5X domain protein CK938_15545 ENOG41081I9 integral membrane protein CK938_15600 ENOG4105C19 ABC transporter CK938_15605 ENOG4105C22 threonyL-tRNA synthetase CK938_15610 ENOG4105FE9 pseudouridine synthase CK938_15645 ENOG4105BZG amino acid carrier protein CK938_15660 ENOG4105K70 DNA-binding protein CK938_15675 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_15680 ENOG4105WQT MbtH domain protein CK938_15685 ENOG4105CEY Amp-dependent synthetase and ligase CK938_15690 ENOG4105WQI isochorismatase CK938_15695 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CK938_15700 ENOG4105E4F Isochorismate synthase CK938_15705 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase CK938_15715 ENOG4105FCD Major Facilitator CK938_15750 ENOG4107RFY SbcCD D subunit CK938_15765 ENOG4105E39 Enoyl-CoA hydratase CK938_15770 ENOG4105N14 lysine exporter protein LysE YggA CK938_15780 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CK938_15785 ENOG4105C1G acyl-Coa dehydrogenase CK938_15790 ENOG4105CR4 methylisocitrate lyase CK938_15795 ENOG4105DXD 2-methylcitrate dehydratase CK938_15805 ENOG4105W8X HesB YadR YfhF-family protein CK938_15810 ENOG4105CZM Major Facilitator CK938_15820 ENOG4105BZ4 penicillin-binding protein CK938_15860 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) CK938_15900 ENOG4108AEY RNA polymerase sigma factor CK938_15940 ENOG4108TFU terminase (Small subunit) CK938_15955 ENOG4105SZ6 Thioredoxin CK938_15965 ENOG410841Q phosphoesterase PA-phosphatase related protein CK938_15970 ENOG4108N23 SpoOM-related protein CK938_16010 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CK938_16015 ENOG4108JUB Transcriptional regulator CK938_16020 ENOG4108TSC N-acetyltransferase CK938_16025 ENOG4107S4Y M20 DapE family protein YgeY CK938_16040 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CK938_16070 ENOG4105C37 (CBS) domain CK938_16105 ENOG4105E90 ABC transporter CK938_16110 ENOG4108IJ8 ABC transporter CK938_16140 ENOG4108YV3 Protein of unknown function (DUF2711) CK938_16185 ENOG4105WH1 Two component transcriptional regulator luxr family CK938_16190 ENOG4105BZU Histidine kinase CK938_16195 ENOG4105D8X mechanosensitive ion channel CK938_16200 ENOG4107Y70 Heat shock protein CK938_16225 ENOG4105F0I Aminotransferase CK938_16230 ENOG4108MES Periplasmic binding protein CK938_16250 ENOG4105CAQ asparagine synthetase CK938_16255 ENOG4107Y70 Heat shock protein CK938_16260 ENOG4108KF3 Electron transport protein SCO1 SenC CK938_16265 ENOG4105E8R UPF0173 metal-dependent hydrolase CK938_16270 ENOG4108RCR degv family CK938_16285 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CK938_16295 ENOG4108UT2 hemolysin iii CK938_16300 ENOG4105E9Q Acyl-transferase CK938_16305 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) CK938_16310 ENOG4107RVG penicillin-binding protein CK938_16330 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) CK938_16345 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 CK938_16370 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CK938_16375 ENOG4105KD7 acetyltransferase CK938_16390 ENOG4105C0A alcohol dehydrogenase CK938_16395 ENOG4105CY2 Citrate transporter CK938_16400 ENOG4107XGZ Hydrolase CK938_16420 ENOG4105C8J )-transporter CK938_16470 ENOG4105EC2 ftsk spoIIIe CK938_16490 ENOG4105C5S asparaginyl-tRNA synthetase CK938_16500 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) CK938_16520 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) CK938_16550 ENOG4107YX5 Pfam:DUF548 CK938_16580 ENOG4108UUM single-stranded DNA-binding protein CK938_16595 ENOG4105C5H ABC transporter CK938_16620 ENOG4105MCT stage V sporulation protein S CK938_16645 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) CK938_16650 ENOG4108IFG nitrite reductase, (NAD(P)H) CK938_16655 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit CK938_16660 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) CK938_16665 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein CK938_16670 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein CK938_16700 ENOG4108ZAF Molybdopterin CK938_16705 ENOG4105CVM Molybdenum cofactor synthesis domain protein CK938_16710 ENOG4105D06 uba thif-type nad fad binding protein CK938_16715 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CK938_16720 ENOG4107V6Q Cyclic nucleotide-binding domain CK938_16730 ENOG4105R3A Nitrate reductase CK938_16735 ENOG4108IUE nitrate reductase beta subunit CK938_16755 ENOG4105C7R Atpase associated with various cellular activities aaa_3 CK938_16770 ENOG4108V06 Glutathione peroxidase CK938_16780 ENOG4105CNW domain protein CK938_16795 ENOG4105EMN RNA polymerase sigma factor CK938_16800 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CK938_16810 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CK938_16815 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) CK938_16835 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) CK938_16860 ENOG4105KBJ sporulation protein ytfj CK938_16885 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) CK938_16915 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CK938_16920 ENOG4108JYZ YitT family CK938_16925 ENOG41087PP glycosyltransferase MGT family CK938_16940 ENOG4107RBS Methyltransferase CK938_16945 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CK938_16955 ENOG4108X4Q Hydrolase CK938_17035 ENOG41082YX Transcriptional regulator, arsr family CK938_17040 ENOG4105D6J arsenicaL-resistance protein CK938_17090 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) CK938_17100 ENOG4108VXD carboxy-peptidase CK938_17110 ENOG4108ZRV stage ii sporulation protein p CK938_17130 ENOG4108Z7R Chaperone CsaA CK938_17150 ENOG4105C37 (CBS) domain CK938_17155 ENOG4105SXS Protein of unknown function (DUF456) CK938_17175 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) CK938_17185 ENOG4108S4H thioesterase Superfamily protein CK938_17195 ENOG4108PJD permease CK938_17210 ENOG4107T5V SNARE associated Golgi CK938_17230 ENOG4105CVJ phosphoglycerate mutase CK938_17255 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CK938_17265 ENOG4105K4T epimerase CK938_17275 ENOG4105DSE periplasmic solute binding protein CK938_17280 ENOG4108IBT Inherit from COG: transposase CK938_17295 ENOG4105CKI cobalamin synthesis protein CK938_17300 ENOG4107QM2 Aldo Keto reductase CK938_17305 ENOG4105VMI -acetyltransferase CK938_17320 ENOG4105DEN Luciferase family CK938_17335 ENOG4108WPJ Ferritin-like domain CK938_17340 ENOG4108K88 Membrane CK938_17360 ENOG4105C8Q Methyl-accepting chemotaxis CK938_17390 ENOG4107XZQ multidrug resistance protein CK938_17395 ENOG4105CPC Aldo Keto reductase CK938_17400 ENOG4105YVS arsR family transcriptional regulator CK938_17410 ENOG4105KRN Transcriptional regulator, abrb family CK938_17465 ENOG4108ZUB Lysine exporter protein (Lyse ygga) CK938_17475 ENOG4105YWU small acid-soluble spore protein CK938_17485 ENOG4105VRR gCN5-related N-acetyltransferase CK938_17490 ENOG4105KT7 mgtC SapB transporter CK938_17500 ENOG4107VMI polysaccharide deacetylase CK938_17510 ENOG4108KGH TRANSCRIPTIONal CK938_17535 ENOG4105D6E homoserine dehydrogenase CK938_17555 ENOG4108ZJ4 polysaccharide deacetylase CK938_17560 ENOG41075D4 Aminoglycoside 6-adenylyltransferase CK938_17575 ENOG4105BZU Histidine kinase CK938_17580 ENOG4105EFI regulatoR CK938_17585 ENOG4105BZ1 (ABC) transporter CK938_17640 ENOG4108UT6 Transferase hexapeptide repeat containing protein CK938_17650 ENOG4105K64 Glycosyl transferase, family 2 CK938_17660 ENOG4108JJ8 (ABC) transporter CK938_17665 ENOG4108JJ9 ABC, transporter CK938_17670 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CK938_17675 ENOG4105C4M (Ubiquinol oxidase) subunit I CK938_17695 ENOG4105MDS 4-oxalocrotonate tautomerase CK938_17715 ENOG4105C32 Amino acid ABC transporter (Permease) CK938_17720 ENOG4108IV0 ABC, transporter CK938_17725 ENOG4105C0Z ABC transporter CK938_17735 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CK938_17740 ENOG4108Z7G MaoC domain protein dehydratase CK938_17755 ENOG4105CKI cobalamin synthesis protein CK938_17765 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CK938_17770 ENOG4106F5Q Membrane CK938_17785 ENOG4108TVJ Nitroreductase CK938_17790 ENOG4107ZXU DSBA oxidoreductase CK938_17795 ENOG4108Z40 Transcriptional regulator CK938_17800 ENOG4105GZI Transcriptional regulator CK938_17805 ENOG4107RT3 EamA-like transporter family CK938_17810 ENOG4105KTB nuclear export factor GLE1 CK938_17815 ENOG4108T5E Copper resistance protein CK938_17865 ENOG4107RAQ aminopeptidase CK938_17885 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) CK938_17890 ENOG4105D9N nucleoside CK938_17900 ENOG4107RHR regulatoR CK938_17930 ENOG4105C0X amino acid CK938_17935 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CK938_17945 ENOG4105C72 UPF0176 protein CK938_17950 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) CK938_17970 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_17975 ENOG41068WN CK938_18030 ENOG4105F6J Alpha beta hydrolase fold CK938_18050 ENOG4105CYC Transferase CK938_18055 ENOG4105DY9 regulatoR CK938_18065 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CK938_18070 ENOG4105C6X Major Facilitator CK938_18095 ENOG4105C7B Threonine dehydratase CK938_18105 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase CK938_18110 ENOG4108ZP8 Acetolactate synthase small subunit CK938_18115 ENOG4105C7K acetolactate synthase CK938_18120 ENOG4105CM2 brancheD-chain amino acid aminotransferase CK938_18125 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) CK938_18150 ENOG4105H67 Protein of unknown function (DUF421) CK938_18155 ENOG4105X5K response regulator receiver protein CK938_18165 ENOG4105C8J )-transporter CK938_18185 ENOG4105C6T cysteine synthase CK938_18190 ENOG4105EU0 Major facilitator Superfamily CK938_18200 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CK938_18215 ENOG4105DXI Major Facilitator superfamily CK938_18230 ENOG4105CSR polyphosphate kinase 2 CK938_18275 ENOG4105FVX CK938_18305 ENOG41067QW Transcriptional regulator CK938_18345 ENOG4105C6K Malic enzyme CK938_18350 ENOG4108IJ0 Aspartate ammonia-lyase CK938_18360 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) CK938_18380 ENOG4105CJ1 ABC, transporter CK938_18420 ENOG4106BRA Membrane CK938_18460 ENOG4105EC3 peptidase S51, dipeptidase E CK938_18470 ENOG4107QJQ Mate efflux family protein CK938_18490 ENOG4105C9Q fumarate hydratase class II CK938_18495 ENOG4105DFD Na H antiporter CK938_18505 ENOG4108UZ3 Transporter CK938_18510 ENOG4105DRR Transcriptional regulator, GntR family CK938_18520 ENOG4105PGM cation diffusion facilitator family transporter CK938_18540 ENOG4105CAQ asparagine synthetase CK938_18550 ENOG4105K56 Transcriptional regulator CK938_18570 ENOG4105CVJ phosphoglycerate mutase CK938_18595 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CK938_18615 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) CK938_18620 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component CK938_18625 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CK938_18630 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CK938_18635 ENOG4105DUM transcriptional regulator, lysR family CK938_18660 ENOG4105KAC Antibiotic biosynthesis monooxygenase CK938_18680 ENOG41062JF Transcriptional regulator CK938_18705 ENOG4105KTQ flagellar basal-body rod protein CK938_18710 ENOG4105FZW flagellar biosynthesis regulator FlhF CK938_18715 ENOG4105D7B Flagellar biosynthesis protein flha CK938_18720 ENOG4105D00 flagellar biosynthetic protein flhB CK938_18730 ENOG4105VS8 Flagellar biosynthetic protein fliq CK938_18735 ENOG4105CN7 Flagellar biosynthetic protein FliP CK938_18745 ENOG4105DD5 Flagellar motor switch protein CK938_18750 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CK938_18765 ENOG4105I03 Flagellin CK938_18785 ENOG4107R88 Chemotaxis protein (CheV) CK938_18800 ENOG4105BZE flagellar hook protein, FlgE CK938_18830 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CK938_18835 ENOG4107U2N Flagellar M-ring protein CK938_18840 ENOG41075Z6 flagellar hook-basal body complex protein fliE CK938_18845 ENOG4108ZC9 flagellar basal-body rod protein flgc CK938_18850 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CK938_18865 ENOG4105DTS flagellar hook-associated CK938_18870 ENOG4105DTJ flagellar hook-associated protein CK938_18875 ENOG4105E1Q flagellar hook-associated protein CK938_18895 ENOG4105BZU Histidine kinase CK938_18910 ENOG4105DD5 Flagellar motor switch protein CK938_18915 ENOG4105CBS Chea signal transduction histidine kinase CK938_18920 ENOG4107YTP response regulator receiver protein CK938_18925 ENOG4105ER2 Ompa motb domain protein CK938_18940 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) CK938_18970 ENOG4107Y80 Major Facilitator superfamily CK938_19000 ENOG41080C8 DUF218 domain CK938_19005 ENOG4105H67 Protein of unknown function (DUF421) CK938_19015 ENOG4108Z5V transcriptional regulator, merr family CK938_19020 ENOG4105CN5 Metallo-Beta-Lactamase CK938_19025 ENOG4107RWR Sodium hydrogen exchanger CK938_19040 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CK938_19105 ENOG41081VK Ribonuclease CK938_19125 ENOG4108SZE gCN5-related N-acetyltransferase CK938_19135 ENOG4108NHD germination protein CK938_19150 ENOG4108ZJ4 polysaccharide deacetylase CK938_19155 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CK938_19170 ENOG41090MY MarR family Transcriptional regulator CK938_19175 ENOG41086D8 Transcriptional regulator CK938_19190 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) CK938_19195 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_19205 ENOG4108ZHR arsR family transcriptional regulator CK938_19210 ENOG4105C4R Atp-dependent dna helicase CK938_19215 ENOG4105C4R Atp-dependent dna helicase CK938_19260 ENOG4105DQU oxidoreductase, subunit beta CK938_19265 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein CK938_19270 ENOG4108IGT Dipeptidase CK938_19275 ENOG4105MCT stage V sporulation protein S CK938_19280 ENOG4105D48 metallophosphoesterase CK938_19285 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) CK938_19305 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase CK938_19320 ENOG4105XZV Protein of unknown function (DUF3243) CK938_19325 ENOG4108RKS Short-chain dehydrogenase reductase Sdr CK938_19345 ENOG4105UIB (ABC) transporter CK938_19350 ENOG4108JQ9 ABC transporter CK938_19355 ENOG4105DIH basic membrane CK938_19360 ENOG4105FDP GntR family transcriptional regulator CK938_19370 ENOG4107QZI cell division protein FtsK CK938_19380 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit CK938_19390 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) CK938_19400 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CK938_19405 ENOG4108S0H Dipicolinic acid synthetase, b subunit CK938_19410 ENOG4105E35 Dipicolinate synthase subunit A CK938_19420 ENOG4105C1V Peptidase, M16 CK938_19440 ENOG4105DTN riboflavin biosynthesis protein ribF CK938_19455 ENOG4105W7A Protein of unknown function (DUF503) CK938_19465 ENOG4105VHM ribosomal protein CK938_19470 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination CK938_19475 ENOG4105CHV Transcription elongation factor NusA CK938_19485 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) CK938_19500 ENOG4105DZP Membrane-associated zinc metalloprotease CK938_19510 ENOG4105KNE Phosphatidate cytidylyltransferase CK938_19555 ENOG4108HE4 integrase family CK938_19565 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CK938_19570 ENOG4105C79 DNA protecting protein DprA CK938_19575 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CK938_19590 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) CK938_19615 ENOG4105VB6 UPF0109 protein CK938_19635 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CK938_19640 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) CK938_19655 ENOG4105CHR reductase CK938_19660 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CK938_19675 ENOG4105CB5 ATP-dependent DNA helicase recG CK938_19680 ENOG4105DP4 dak2 domain fusion protein ylov CK938_19685 ENOG4108ZAA Alkaline-shock protein CK938_19700 ENOG4105FJ0 thiamine CK938_19705 ENOG4105DJV ribulose-phosphate 3-epimerase CK938_19715 ENOG4105D9P serine threonine protein kinase CK938_19720 ENOG4108ZF3 Phosphatase CK938_19730 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B CK938_19740 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CK938_19745 ENOG4105C25 Primosomal protein n' CK938_19750 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CK938_19770 ENOG4105DSJ YicC domain protein CK938_19780 ENOG4105F23 Fibronectin-binding protein CK938_19790 ENOG4105DC7 peptidase M24 CK938_19880 ENOG4105C34 Pseudouridine synthase CK938_19905 ENOG4105DBK s4 domain protein CK938_19910 ENOG41067XK integral membrane protein CK938_19920 ENOG4105DFA alanine racemase domain protein CK938_19925 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CK938_19930 ENOG4105WR5 sporulation protein, YlmC YmxH family CK938_19940 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_19950 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CK938_19955 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CK938_19960 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) CK938_19975 ENOG4105CNI cell division protein FtsW CK938_19990 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CK938_19995 ENOG4105CJN penicillin-binding protein CK938_20000 ENOG4105CJN penicillin-binding protein CK938_20005 ENOG41068DC Essential cell division protein (By similarity) CK938_20040 ENOG4105KNH Nucleic acid-binding protein CK938_20050 ENOG41063PX domain protein CK938_20055 ENOG4105D78 K07001 NTE family protein CK938_20060 ENOG4105H20 Sporulation integral membrane protein YlbJ CK938_20070 ENOG4106H78 methyltransferase CK938_20090 ENOG4107TB6 phosphoglycerate mutase CK938_20105 ENOG4106UY4 Inherit from COG: Scp-like extracellular CK938_20120 ENOG4105EKQ RNA-directed DNA polymerase CK938_20165 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) CK938_20175 ENOG4105CNI cell division protein FtsW CK938_20190 ENOG4108IAB Phoh family CK938_20210 ENOG4105QA2 CK938_20215 ENOG4105CI3 gtp-binding protein typa CK938_20225 ENOG4105ECY inositol monophosphatase CK938_20245 ENOG4105CXN decarboxylase CK938_20295 ENOG4105CPP Dehydrogenase, E1 component CK938_20310 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) CK938_20315 ENOG4108X4Q Hydrolase CK938_20330 ENOG4105CN5 Metallo-Beta-Lactamase CK938_20335 ENOG4107ZYR domain protein CK938_20370 ENOG4108XRC Protein of unknown function (DUF458) CK938_20380 ENOG4107IN1 Protein of unknown function (DUF1797) CK938_20395 ENOG4105EPM Diguanylate phosphodiesterase CK938_20400 ENOG4105K6S Short-chain dehydrogenase reductase Sdr CK938_20420 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CK938_20430 ENOG4105UIN CK938_20465 ENOG4105D7V transposase CK938_20505 ENOG4108HGU Histidine kinase CK938_20515 ENOG4105CHM Aminotransferase CK938_20520 ENOG4105FKQ transcriptional regulator CK938_20525 ENOG4105EG2 ABC transporter, permease CK938_20535 ENOG4107FKK extracellular solute-binding protein family 1 CK938_20545 ENOG4105CG3 alpha amylase, catalytic region CK938_20590 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CK938_20595 ENOG4105CHU acetyl-coa acetyltransferase CK938_20630 ENOG4105K7K Transcriptional regulator CK938_20635 ENOG4105DTD Dehydrogenase CK938_20655 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase CK938_20695 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase CK938_20705 ENOG4106TD9 Diguanylate cyclase CK938_20725 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CK938_20740 ENOG4105CID antiterminator CK938_20750 ENOG4105FDP GntR family transcriptional regulator CK938_20760 ENOG4105CE4 GlcNAc 6-P deacetylase CK938_20805 ENOG4107ZE5 PPIases accelerate the folding of proteins CK938_20810 ENOG4105PTM secreted protein CK938_20815 ENOG4105J7I hydrolase CK938_20825 ENOG4105G6R Stage v sporulation protein ae CK938_20835 ENOG4105CZ3 stage V sporulation protein ad CK938_20840 ENOG41090VF Stage v sporulation protein ac CK938_20860 ENOG4105C8J )-transporter CK938_20865 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_20875 ENOG41082AN stage II sporulation protein CK938_20880 ENOG4105DZ1 carboxypeptidase CK938_20890 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family CK938_20895 ENOG4105DVE abc transporter atp-binding protein CK938_20935 ENOG4105D7N magnesium and cobalt transport protein CorA CK938_20960 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CK938_20970 ENOG4105I3K Ferric uptake regulator, Fur family CK938_20975 ENOG4105MZ9 stage II sporulation protein m CK938_20995 ENOG4105CPC Aldo Keto reductase CK938_21005 ENOG4105RHY Pfam:UPF0157 CK938_21025 ENOG4107SKW Inherit from COG: Alpha beta hydrolase CK938_21035 ENOG4105ETE Transcriptional regulator (LacI family CK938_21040 ENOG4108YM7 Gcn5-related n-acetyltransferase CK938_21060 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CK938_21065 ENOG4108R6K riboflavin synthase, subunit alpha CK938_21090 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CK938_21095 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CK938_21110 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) CK938_21125 ENOG4105DFD Na H antiporter CK938_21130 ENOG4105CGH 5'-nucleotidase CK938_21225 ENOG4108IXY short-chain dehydrogenase reductase CK938_21230 ENOG41069FQ Metallo-beta-lactamase superfamily CK938_21235 ENOG4105II7 pyrroline-5-carboxylate reductase CK938_21240 ENOG4105EJQ L-serine dehydratase CK938_21265 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CK938_21275 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) CK938_21285 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CK938_21290 ENOG4105D9U N-acetyltransferase CK938_21305 ENOG4108VZI ErfK ybiS ycfS ynhG family protein CK938_21310 ENOG4108QEG Membrane CK938_21315 ENOG4105CDA abc transporter atp-binding protein CK938_21320 ENOG4105E5Q amino acid AbC transporter CK938_21325 ENOG4108HW3 (ABC) transporter CK938_21345 ENOG4108QY0 Membrane CK938_21360 ENOG4105C7S Dehydrogenase CK938_21365 ENOG4105CPP Dehydrogenase, E1 component CK938_21385 ENOG4107RDP Dehydrogenase CK938_21400 ENOG4108JUB Transcriptional regulator CK938_21410 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CK938_21420 ENOG4107QQR Sporulation CK938_21430 ENOG4105S1Z Stage IV sporulation protein B CK938_21435 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CK938_21445 ENOG4105DX0 Hemolysin A CK938_21455 ENOG4105CTB Polyprenyl synthetase CK938_21480 ENOG4108ZSR alkaline shock protein CK938_21485 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CK938_21510 ENOG410644B Stage III sporulation protein af CK938_21520 ENOG4105KQ4 Stage iii sporulation protein ad CK938_21525 ENOG4108CQH stage III sporulation protein AC CK938_21530 ENOG4105KR5 Stage iii sporulation protein CK938_21535 ENOG4105CD2 stage iii sporulation protein aa CK938_21560 ENOG4105DC7 peptidase M24 CK938_21575 ENOG4105CBJ Metal-dependent enzyme CK938_21585 ENOG4107YBY Hydrolase CK938_21620 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) CK938_21625 ENOG4105WZW rhodanese family CK938_21650 ENOG41080TC multidrug resistance protein CK938_21690 ENOG4105CJ1 ABC, transporter CK938_21695 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family CK938_21725 ENOG4105C0D helicase CK938_21855 ENOG4105C3R Methionine synthase CK938_21865 ENOG4105C28 cystathionine CK938_21870 ENOG4105C28 cystathionine CK938_21890 ENOG4105C5X domain protein CK938_21900 ENOG4105DKQ ROK family CK938_21910 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CK938_21925 ENOG4108UTW Plays a role in the regulation of phosphate uptake CK938_21930 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) CK938_21935 ENOG4105E2Z phosphate ABC transporter (Permease CK938_21940 ENOG4105C8U phosphate abc transporter CK938_21945 ENOG4105PWN phosphate abc transporter CK938_21950 ENOG4107RF6 penicillin-binding protein CK938_21960 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CK938_21985 ENOG4105N80 Ferric uptake regulator, Fur family CK938_21995 ENOG4105FDK ABC transporter CK938_22000 ENOG4108JYZ YitT family CK938_22005 ENOG41069ZM Protein of unknown function (DUF2624) CK938_22030 ENOG4105EGD dinuclear metal center protein, YbgI family CK938_22045 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_22050 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CK938_22090 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) CK938_22095 ENOG4105KG3 cytidine deaminase CK938_22100 ENOG4107YR5 Diacylglycerol kinase CK938_22110 ENOG4105CTJ Metal Dependent Phosphohydrolase CK938_22115 ENOG4105C9A Phoh family CK938_22130 ENOG41068P3 sporulation protein YqfC CK938_22135 ENOG4105KTH gatB Yqey CK938_22145 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) CK938_22150 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CK938_22180 ENOG4105CSA Coproporphyrinogen iii oxidase CK938_22185 ENOG4105KVH Transcriptional regulator CK938_22210 ENOG4105TQK DNA polymerase iii, delta' subunit CK938_22220 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 CK938_22225 ENOG4108UK2 deaminase CK938_22230 ENOG4105KQC Competence protein CK938_22240 ENOG4105DXX methyltransferase CK938_22250 ENOG4108WF2 Metal Dependent Phosphohydrolase CK938_22260 ENOG410812S Rna-binding protein CK938_22270 ENOG4105CQW ribosome biogenesis GTPase YqeH CK938_22275 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase CK938_22290 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_22310 ENOG4108TVJ Nitroreductase CK938_22325 ENOG4105G6Z alkaline phosphatase CK938_22330 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CK938_22335 ENOG4108MUZ hydrolase CK938_22370 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin CK938_22375 ENOG4105MIR Phenylalanine 4-monooxygenase CK938_22385 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase CK938_22425 ENOG4105S6R Iron-hydroxamate transporter permease subunit CK938_22430 ENOG4108HUF Transporter CK938_22445 ENOG4108EKI Dehydrogenase CK938_22450 ENOG4105C28 cystathionine CK938_22480 ENOG4107XRG penicillin-binding protein CK938_22495 ENOG4105CFP Peptidase U32 CK938_22500 ENOG4105XYU peptidase (U32 family) CK938_22505 ENOG4108VQJ O-methyltransferase CK938_22510 ENOG4105HHA aminodeoxychorismate lyase CK938_22540 ENOG4105C02 permease CK938_22555 ENOG41060CR CK938_22560 ENOG4105C7H Helicase, RecD TraA family CK938_22575 ENOG4105C3J Cysteine desulfurase CK938_22585 ENOG4105D1H recombination factor protein RarA CK938_22590 ENOG4108VCI transcription factor, rsfa family CK938_22600 ENOG4105CUZ uba thif-type nad fad binding protein CK938_22630 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CK938_22640 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CK938_22645 ENOG41076HS cation diffusion facilitator family transporter CK938_22650 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CK938_22660 ENOG4105CKP Polysaccharide Biosynthesis Protein CK938_22665 ENOG4108QG2 Membrane CK938_22675 ENOG4105VIE preprotein translocase, subunit YajC CK938_22690 ENOG41061AI Protein of unknown function (DUF2905) CK938_22705 ENOG4108HUF Transporter CK938_22715 ENOG4108IPJ Membrane CK938_22720 ENOG41082BM Transcriptional regulator, arsr family CK938_22745 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CK938_22750 ENOG4108IYU L-aspartate oxidase CK938_22765 ENOG4108RPX mosc domain containing protein CK938_22770 ENOG4105CQC Prephenate dehydratase CK938_22790 ENOG4105EWM Histidine kinase CK938_22815 ENOG4105X36 (ribosomal) protein CK938_22825 ENOG4105C03 ribonuclease CK938_22840 ENOG4107QMS site-determining protein CK938_22855 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CK938_22860 ENOG4105DFF Rod shape-determining protein mreb CK938_22885 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CK938_22900 ENOG41068KH stage VI sporulation protein D CK938_22910 ENOG4105D52 delta-aminolevulinic acid dehydratase CK938_22935 ENOG4105K56 Transcriptional regulator CK938_22955 ENOG4108IUQ atp-dependent protease CK938_22985 ENOG4108QCI YvbH-like oligomerisation region CK938_23005 ENOG4105M59 Phosphodiesterase, mj0936 family CK938_23010 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CK938_23020 ENOG4108XJQ germination protein CK938_23030 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_23040 ENOG4105KBX Transcriptional regulator, TetR family CK938_23050 ENOG4105PFC Transcriptional regulator CK938_23065 ENOG4105DZC cytosine deaminase CK938_23070 ENOG4105DZC cytosine deaminase CK938_23075 ENOG4105DEF Extracellular solute-binding protein, family 5 CK938_23080 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CK938_23095 ENOG4108JQ7 (ABC) transporter CK938_23100 ENOG4108HRK Histidine kinase CK938_23105 ENOG4105DY9 regulatoR CK938_23115 ENOG41067S9 phage shock protein C, PspC CK938_23120 ENOG4108JCI Transcriptional regulator CK938_23130 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CK938_23135 ENOG4108Z40 Transcriptional regulator CK938_23140 ENOG4105RHA ABC transporter, permease CK938_23145 ENOG4108IUX (ABC) transporter CK938_23150 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family CK938_23155 ENOG4105ER2 Ompa motb domain protein CK938_23160 ENOG4105E14 MotA TolQ exbB proton channel CK938_23165 ENOG4108VXD carboxy-peptidase CK938_23175 ENOG4105E33 succinate dehydrogenase CK938_23185 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit CK938_23200 ENOG4105K63 Thioredoxin CK938_23205 ENOG4105C10 Electron transfer flavoprotein CK938_23210 ENOG4105BZJ Electron transfer flavoprotein CK938_23215 ENOG41060WC Enoyl-CoA hydratase CK938_23220 ENOG4107Z3H Transcriptional regulator, TetR family CK938_23225 ENOG4105CEY Amp-dependent synthetase and ligase CK938_23280 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_23295 ENOG4105DR4 Methyltransferase CK938_23310 ENOG4105KFN sortase, SrtB family CK938_23315 ENOG4105E0A ABC, transporter CK938_23330 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) CK938_23335 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) CK938_23345 ENOG4105FE9 pseudouridine synthase CK938_23360 ENOG4105DCG PHP domain protein CK938_23410 ENOG4108RWN rrna methyltransferase CK938_23430 ENOG4105C0R drug resistance transporter emrb qaca subfamily CK938_23435 ENOG4105CW7 secretion protein, HlyD family CK938_23440 ENOG4108JGH Tetr family transcriptional regulator CK938_23445 ENOG4105CN9 Peptidase m42 family protein CK938_23465 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) CK938_23470 ENOG4105C22 threonyL-tRNA synthetase CK938_23475 ENOG4108TDW sporulation protein YtxC CK938_23495 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) CK938_23505 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase CK938_23510 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CK938_23525 ENOG4105C2M dna polymerase I CK938_23530 ENOG4105BZU Histidine kinase CK938_23535 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_23560 ENOG4108HMX isocitrate dehydrogenase (NADP) CK938_23565 ENOG4105BZN citrate synthase CK938_23580 ENOG4108REF Sporulation integral membrane protein ytvi CK938_23585 ENOG4105FS0 cytoplasmic membrane protein CK938_23610 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family CK938_23615 ENOG4105C6K Malic enzyme CK938_23620 ENOG4105C0B DNA polymerase III (alpha subunit) CK938_23625 ENOG4105VV2 CK938_23640 ENOG4105SFS phosphoesterase RecJ domain protein CK938_23685 ENOG4105DC7 peptidase M24 CK938_23720 ENOG4105Z7P Acetyltransferase (GNAT) family CK938_23725 ENOG41082W1 Cupin 2, conserved barrel domain protein CK938_23770 ENOG4107YZX Universal stress protein CK938_23820 ENOG4108JYZ YitT family CK938_23850 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CK938_23855 ENOG4105KBJ sporulation protein ytfj CK938_23870 ENOG4105EFZ amidohydrolase CK938_23880 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) CK938_23905 ENOG4105C5Q Transcriptional regulator CK938_23915 ENOG4105U5Y Transcriptional regulator CK938_23925 ENOG4105C28 cystathionine CK938_23960 ENOG4105EMN RNA polymerase sigma factor CK938_23980 ENOG4105F1V Acetoin utilization protein CK938_23985 ENOG4105W87 Cbs domain CK938_23990 ENOG4105DGU Histone deacetylase CK938_24005 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CK938_24015 ENOG4107SNB ankyrin repeat protein YahD CK938_24020 ENOG4105D7V transposase CK938_24025 ENOG4105EP9 oxidoreductase CK938_24055 ENOG4105ETE Transcriptional regulator (LacI family CK938_24080 ENOG4105C88 aminopeptidase CK938_24105 ENOG4108IPJ Membrane CK938_24115 ENOG4105K7K Transcriptional regulator CK938_24145 ENOG4108VDD TRNA binding domain protein CK938_24175 ENOG4105C8F Beta-lactamase domain protein CK938_24190 ENOG4108V15 phosphotransferase enzyme family CK938_24195 ENOG4108IUM Glycogen debranching enzyme CK938_24210 ENOG4107QSE Dipeptidase CK938_24215 ENOG4105YW5 deoR family transcriptional regulator CK938_24230 ENOG4105CBX hi0933 family CK938_24275 ENOG4108VJ1 Transcriptional regulator (CarD family CK938_24280 ENOG4107EXU Short-chain dehydrogenase reductase Sdr CK938_24300 ENOG4108ZAF Molybdopterin CK938_24305 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein CK938_24310 ENOG4105CVM Molybdenum cofactor synthesis domain protein CK938_24320 ENOG4105D06 uba thif-type nad fad binding protein CK938_24325 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CK938_24345 ENOG41085GJ domain protein CK938_24355 ENOG4105DWV Homoserine O-trans-acetylase CK938_24365 ENOG4108B31 Spore germination protein CK938_24395 ENOG410605W Major Facilitator CK938_24400 ENOG4107S91 Sodium hydrogen exchanger CK938_24405 ENOG4105NCW Trka-c domain protein CK938_24425 ENOG4105C19 ABC transporter CK938_24445 ENOG4105N5T Radical SAM Protein CK938_24455 ENOG4105CIG ABC transporter CK938_24490 ENOG4105E8V Alpha Beta Hydrolase Fold protein CK938_24495 ENOG4108Z0R Transferase CK938_24500 ENOG4105YVM Phosphoesterase, PA-phosphatase related CK938_24505 ENOG4105BZF Glycosyl transferase (Group 1 CK938_24515 ENOG4108RIR Molybdenum cofactor biosynthesis protein CK938_24580 ENOG4105EGD dinuclear metal center protein, YbgI family CK938_24585 ENOG4105BZU Histidine kinase CK938_24590 ENOG4105BZU Histidine kinase CK938_24595 ENOG4107S9D Alpha beta hydrolase CK938_24600 ENOG4107T7U Sulfatase CK938_24620 ENOG4105D2X ABC transporter substrate-binding protein CK938_24630 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component CK938_24680 ENOG4108V2W Carbonate dehydratase CK938_24685 ENOG4105C4M (Ubiquinol oxidase) subunit I CK938_24690 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CK938_24775 ENOG4105BZU Histidine kinase CK938_24780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_24805 ENOG4108UGV hypoxanthine phosphoribosyltransferase CK938_24810 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) CK938_24830 ENOG4105C19 ABC transporter CK938_24855 ENOG4107ZTW SNARE associated Golgi CK938_24880 ENOG4105C19 ABC transporter CK938_24885 ENOG41086D8 Transcriptional regulator CK938_24895 ENOG41082BM Transcriptional regulator, arsr family CK938_24935 ENOG4105C6Z Gluconate CK938_24940 ENOG4105D7V transposase CK938_24945 ENOG4105FDP GntR family transcriptional regulator CK938_24965 ENOG41069H0 dihydroorotase EC 3.5.2.3 CK938_24985 ENOG4105DTQ mandelate racemase muconate lactonizing CK938_24995 ENOG4108IPT Naphthoate synthase CK938_25000 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) CK938_25010 ENOG4105E4F Isochorismate synthase CK938_25015 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CK938_25025 ENOG4105VEQ Cold shock protein CK938_25075 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin CK938_25085 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) CK938_25185 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation CK938_25225 ENOG4105KT7 mgtC SapB transporter CK938_25230 ENOG4107PBV potassium channel CK938_25250 ENOG4105WG9 Conserved Protein CK938_25260 ENOG4105CHM Aminotransferase CK938_25265 ENOG4108ZB6 transcriptional regulator AsnC family CK938_25270 ENOG4105C5I Dehydrogenase CK938_25275 ENOG4108MUZ hydrolase CK938_25285 ENOG4105C87 Aminotransferase class I and II CK938_25295 ENOG4105Y38 Kinase-associated protein B CK938_25305 ENOG4107R3E Citrate transporter CK938_25325 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) CK938_25330 ENOG4105KA0 thioesterase Superfamily protein CK938_25345 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CK938_25365 ENOG41069ER domain protein CK938_25380 ENOG4105CEP NADH dehydrogenase CK938_25415 ENOG4105EWC Purine nucleoside phosphorylase CK938_25435 ENOG4108YX9 iron--sulfur cluster insertion protein erpA CK938_25460 ENOG4108JJA ABC, transporter CK938_25465 ENOG4105C4B ABC transporter, permease CK938_25470 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CK938_25515 ENOG41083MR nifu domain-containing protein CK938_25530 ENOG4108W5N phosphatidylglycerophosphatase a CK938_25540 ENOG4105DYS nad(p)h dehydrogenase (quinone) CK938_25550 ENOG4105D4U had-superfamily hydrolase, subfamily iia CK938_25565 ENOG4105CBT Fructose-1,6-bisphosphatase CK938_25585 ENOG4105MMD transcriptional regulator CK938_25590 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CK938_25595 ENOG4107TXC Transcriptional regulator CK938_25600 ENOG41090T1 Membrane CK938_25625 ENOG4105FAA peptidase M23 CK938_25635 ENOG4105KZD Domain of unknown function (DUF1805) CK938_25640 ENOG4107R8B 5'-nucleotidase CK938_25650 ENOG4105DIW FeS assembly protein SUFB CK938_25655 ENOG4108UNV SUF system FeS assembly protein, NifU family CK938_25660 ENOG4105C9B Cysteine desulfurase CK938_25665 ENOG4105JRK feS assembly protein SufD CK938_25670 ENOG4105C3K feS assembly ATPase SufC CK938_25675 ENOG4105D01 (LipO)protein CK938_25680 ENOG4105D01 (LipO)protein CK938_25685 ENOG4108UMI ABC transporter, permease CK938_25715 ENOG41080E8 Transcriptional regulator, Spx MgsR family CK938_25795 ENOG4108W8B Beta-lactamase domain protein CK938_25800 ENOG4105C1G acyl-Coa dehydrogenase CK938_25805 ENOG4105CHU acetyl-coa acetyltransferase CK938_25825 ENOG4105DZ1 carboxypeptidase CK938_25860 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CK938_25880 ENOG4108SUT Major Facilitator Superfamily CK938_25885 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) CK938_25895 ENOG4107R7I amino acid CK938_25910 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CK938_25920 ENOG4107AYK membrAne CK938_25960 ENOG4107ZTW SNARE associated Golgi CK938_25970 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CK938_25975 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_25980 ENOG4105BZU Histidine kinase CK938_26000 ENOG4105C8Q Methyl-accepting chemotaxis CK938_26005 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer CK938_26010 ENOG4105VG1 fes assembly suf system protein CK938_26015 ENOG4105D4Y metalloprotease CK938_26035 ENOG4107S91 Sodium hydrogen exchanger CK938_26040 ENOG4105NCW Trka-c domain protein CK938_26055 ENOG4108RMU ferritin dps family protein CK938_26075 ENOG4108URH decarboxylase CK938_26095 ENOG4105D9N nucleoside CK938_26100 ENOG4105D9N nucleoside CK938_26115 ENOG4108RYK Nad-dependent epimerase dehydratase CK938_26135 ENOG4105CV8 reductase CK938_26140 ENOG4105F27 Major Facilitator CK938_26145 ENOG4105KVH Transcriptional regulator CK938_26160 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) CK938_26175 ENOG4105C8Q Methyl-accepting chemotaxis CK938_26185 ENOG4105WMR Protein CrcB homolog CK938_26200 ENOG4108MK9 spermidine N(1)-acetyltransferase CK938_26205 ENOG4108VY7 phosphate-starvation-inducible protein PsiE CK938_26220 ENOG4108IPW abc transporter atp-binding protein CK938_26225 ENOG4105CM4 permease protein CK938_26245 ENOG4105EWM Histidine kinase CK938_26250 ENOG4105CJZ response regulator CK938_26255 ENOG4105C19 ABC transporter CK938_26275 ENOG4105C19 ABC transporter CK938_26315 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CK938_26325 ENOG4105XZU Preprotein translocase, subunit SecG CK938_26330 ENOG41067MG lrgb family CK938_26380 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_26400 ENOG41090VF Stage v sporulation protein ac CK938_26405 ENOG4105CZ3 stage V sporulation protein ad CK938_26420 ENOG4108QY0 Membrane CK938_26425 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) CK938_26430 ENOG4105KRI phosphocarrier protein (HPr CK938_26440 ENOG4105CHW UPF0052 protein CK938_26450 ENOG4108Z4K mutator MutT protein CK938_26460 ENOG4105C3M thioredoxin reductase CK938_26470 ENOG4108S4C acetyltransferase CK938_26490 ENOG41086DT Membrane protein of unknown function CK938_26500 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CK938_26515 ENOG4107TXC Transcriptional regulator CK938_26550 ENOG4105DUM transcriptional regulator, lysR family CK938_26560 ENOG4108WS4 fmn reductase CK938_26575 ENOG4105BZ1 (ABC) transporter CK938_26590 ENOG4105CN1 protease CK938_26595 ENOG4105CRP Part of the ABC transporter FtsEX involved in CK938_26600 ENOG4105CAK Cell division ATP-binding protein ftsE CK938_26610 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) CK938_26630 ENOG4105MS2 ribosomal subunit Interface protein CK938_26635 ENOG4105VEQ Cold shock protein CK938_26640 ENOG41081UC Inherit from COG: Competence protein CK938_26650 ENOG4105K4H Nlp p60 protein CK938_26655 ENOG4105KVH Transcriptional regulator CK938_26670 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CK938_26675 ENOG4108KGH TRANSCRIPTIONal CK938_26680 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CK938_26685 ENOG4105C6Y Udp-glucose 6-dehydrogenase CK938_26690 ENOG4105ESV Glycosyl transferase, family 4 CK938_26700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CK938_26720 ENOG4105F8D glycoside hydrolase family 4 CK938_26725 ENOG4105VCP PTS System CK938_26730 ENOG4105CK1 PTS System CK938_26740 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) CK938_26755 ENOG4105VCP PTS System CK938_26765 ENOG4105VZJ PTS System CK938_26785 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase CK938_26790 ENOG4105ECB domain protein CK938_26795 ENOG4107RSM transcriptional regulator CK938_26830 ENOG4105DAA L-lactate CK938_26840 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) CK938_26855 ENOG4105E0M Sulfatase CK938_26885 ENOG4107R8N Glycosyl transferase, family 2 CK938_26895 ENOG4105C94 Transporter CK938_26905 ENOG41069ER domain protein CK938_26915 ENOG4105KBK Zinc finger, swim domain protein CK938_26920 ENOG4105C0D helicase CK938_26950 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CK938_26965 ENOG4107RBB ABC transporter, permease CK938_26970 ENOG4105C19 ABC transporter CK938_26990 ENOG4105CXY transporter CK938_27005 ENOG4105BZU Histidine kinase CK938_27010 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_27015 ENOG4105CMR udp-glucose 4-epimerase CK938_27025 ENOG4108KGH TRANSCRIPTIONal CK938_27030 ENOG4105CMR udp-glucose 4-epimerase CK938_27035 ENOG4105C6Y Udp-glucose 6-dehydrogenase CK938_27060 ENOG4105K64 Glycosyl transferase, family 2 CK938_27080 ENOG4105D3Q Sugar transferase CK938_27085 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CK938_27090 ENOG4108RB3 Capsular polysaccharide biosynthesis protein CK938_27095 ENOG4107YJ4 chain length determinant protein CK938_27100 ENOG4105HTX biosynthesis protein CK938_27105 ENOG4107YJ4 chain length determinant protein CK938_27120 ENOG4105K7W phage-related replication protein CK938_27150 ENOG4105MT0 Sporulation transcriptional regulator spoiiid CK938_27160 ENOG4105FRN stage II sporulation protein CK938_27175 ENOG4105DY9 regulatoR CK938_27195 ENOG4106778 Protein of unknown function (DUF1146) CK938_27200 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CK938_27205 ENOG4105C8S subunit m CK938_27210 ENOG4105D65 subunit l CK938_27235 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CK938_27240 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain CK938_27250 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain CK938_27255 ENOG4105BZU Histidine kinase CK938_27310 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) CK938_27315 ENOG41062M3 atp synthase CK938_27335 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) CK938_27345 ENOG4108YZG isomerase CK938_27365 ENOG4108VGI doxx family CK938_27370 ENOG4107XC4 flavin reductase domain protein, FMN-binding CK938_27390 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) CK938_27400 ENOG4108ZXQ stage ii sporulation protein r CK938_27405 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CK938_27410 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) CK938_27430 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) CK938_27440 ENOG4105CBT Fructose-1,6-bisphosphatase CK938_27450 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) CK938_27485 ENOG4105C1G acyl-Coa dehydrogenase CK938_27490 ENOG4105C1G acyl-Coa dehydrogenase CK938_27495 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase CK938_27505 ENOG4105DF6 Fe-S oxidoreductase CK938_27520 ENOG4105BZU Histidine kinase CK938_27550 ENOG4105BZU Histidine kinase CK938_27555 ENOG4105KCT ABC transporter CK938_27560 ENOG4108M15 ABC transporter CK938_27565 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) CK938_27575 ENOG4105IIU Aminopeptidase CK938_27610 ENOG4105EMN RNA polymerase sigma factor CK938_27625 ENOG410684U Domain of unknown function (DUF1934) CK938_27650 ENOG4105CYW agmatinase CK938_27660 ENOG4105DXB Major Facilitator superfamily CK938_27665 ENOG4107SWG transcriptional regulator MERR family CK938_27670 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CK938_27675 ENOG4105BZ4 penicillin-binding protein CK938_27680 ENOG4108XFG YwhD family CK938_27685 ENOG4108Z4T Peptidase M50 CK938_27690 ENOG41069HH 4-oxalocrotonate tautomerase CK938_27695 ENOG4105DCI Phosphohydrolase CK938_27700 ENOG4108MES Periplasmic binding protein CK938_27705 ENOG4105E0A ABC, transporter CK938_27710 ENOG4105EHG Permease protein CK938_27715 ENOG4105DQ5 transport system permease protein CK938_27725 ENOG4108VCI transcription factor, rsfa family CK938_27740 ENOG4108IJ2 phosphate acetyltransferase CK938_27755 ENOG4108VKI Cell wall hydrolase CK938_27775 ENOG4107SVH Potassium channel protein CK938_27785 ENOG410667J hydrolase CK938_27790 ENOG4105VCH membrane CK938_27800 ENOG4108TU7 Inherit from COG: (ABC) transporter CK938_27805 ENOG4105CJ1 ABC, transporter CK938_27810 ENOG41090WU lipolytic protein G-D-S-L family CK938_27825 ENOG4105D6E homoserine dehydrogenase CK938_27845 ENOG4108Y4K DNA-binding transcriptional activator CK938_27855 ENOG4105WH1 Two component transcriptional regulator luxr family CK938_27860 ENOG4105BZU Histidine kinase CK938_27865 ENOG4105DWF phosphomethylpyrimidine kinase CK938_27870 ENOG4105BZU Histidine kinase CK938_27875 ENOG4105VCD cytoplasmic protein CK938_27880 ENOG4105D22 carbon starvation protein CK938_27885 ENOG4105DY9 regulatoR CK938_27890 ENOG41079KZ Major Facilitator Superfamily CK938_27905 ENOG4105CG5 Glycosyl transferase (Group 1 CK938_27915 ENOG4105EN6 Membrane CK938_27920 ENOG4106YBV Methyl-accepting chemotaxis CK938_27930 ENOG4108S4H thioesterase Superfamily protein CK938_27935 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) CK938_27950 ENOG4105K64 Glycosyl transferase, family 2 CK938_27965 ENOG4105C5H ABC transporter CK938_27970 ENOG41067SE Tetr family transcriptional regulator CK938_27980 ENOG4105E0X reductase CK938_27990 ENOG4106F5Q Membrane CK938_28005 ENOG4105DY9 regulatoR CK938_28010 ENOG4108HRK Histidine kinase CK938_28015 ENOG4107RGD Major Facilitator superfamily CK938_28035 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CK938_28045 ENOG4105IW1 AmiS UreI transporter CK938_28055 ENOG4105CMR udp-glucose 4-epimerase CK938_28060 ENOG4108UT2 hemolysin iii CK938_28070 ENOG4105C1J atp-dependent rna helicase CK938_28080 ENOG4105DPN Oligoendopeptidase f CK938_28100 ENOG4105C0H protease CK938_28105 ENOG4105Q2H domain protein CK938_28120 ENOG4105BZU Histidine kinase CK938_28125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CK938_28155 ENOG4105CDU Replicative dna helicase CK938_28165 ENOG4105BZR domain protein CK938_28170 ENOG4108XMW Membrane CK938_28180 ENOG4108UUM single-stranded DNA-binding protein CK938_28190 ENOG4105C3G gtp-binding protein CK938_28195 ENOG4105VDK protein, conserved in bacteria CK938_28200 ENOG4105D8X mechanosensitive ion channel CK938_28205 ENOG4108ZDA Sporulation protein YyaC CK938_28210 ENOG4105FA0 parb-like partition protein CK938_28215 ENOG4107QJE Chromosome Partitioning Protein CK938_28245 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CK938_28300 ENOG4105VN1 Heat shock protein CK938_28310 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein CK938_28345 ENOG4105VN1 Heat shock protein CK938_28370 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)