locus-tag	class	description
CK938_00010	COG0592	DNA-directed DNA polymerase activity
CK938_00015	COG2501	S4 domain
CK938_00025	COG0187	DNA topoisomerase II activity
CK938_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK938_00065	COG0516	GMP reductase activity
CK938_00065	COG0517	IMP dehydrogenase activity
CK938_00070	COG1686	Belongs to the peptidase S11 family
CK938_00100	COG1428	Deoxynucleoside kinase
CK938_00105	COG1428	Deoxynucleoside kinase
CK938_00110	COG1335	isochorismatase
CK938_00120	COG0590	tRNA wobble adenosine to inosine editing
CK938_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CK938_00185	COG1982	Orn Lys Arg decarboxylase major
CK938_00195	COG0470	DNA polymerase III
CK938_00200	COG1774	PSP1 C-terminal conserved region
CK938_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CK938_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CK938_00225	COG2002	toxin-antitoxin pair type II binding
CK938_00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK938_00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK938_00235	COG0084	hydrolase, TatD family'
CK938_00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CK938_00255	COG4466	Protein conserved in bacteria
CK938_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CK938_00280	COG0251	oxidation-reduction process
CK938_00295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK938_00310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK938_00315	COG2002	toxin-antitoxin pair type II binding
CK938_00320	COG2244	polysaccharide biosynthetic process
CK938_00325	COG3956	TIGRFAM MazG family protein
CK938_00330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK938_00350	COG1098	S1 RNA binding domain
CK938_00365	COG2208	phosphoserine phosphatase activity
CK938_00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK938_00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK938_00400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK938_00405	COG0512	Glutamine amidotransferase of anthranilate synthase
CK938_00410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK938_00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK938_00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CK938_00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK938_00430	COG1396	sequence-specific DNA binding
CK938_00435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK938_00525	COG3880	PFAM UvrB UvrC protein
CK938_00535	COG0542	response to heat
CK938_00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CK938_00550	COG4956	integral membrane protein (PIN domain superfamily)
CK938_00570	COG1045	serine acetyltransferase
CK938_00585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK938_00590	COG3688	RNA-binding protein containing a PIN domain
CK938_00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CK938_00605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK938_00610	COG0250	Participates in transcription elongation, termination and antitermination
CK938_00635	COG2813	Specifically methylates the guanine in position
CK938_00650	COG1358	cellular component organization or biogenesis
CK938_00760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CK938_00785	COG0201	protein transport
CK938_00795	COG0024	Methionine aminopeptidase
CK938_00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK938_00835	COG1122	ATPase activity
CK938_00840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CK938_00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK938_00870	COG0489	protein tyrosine kinase activity
CK938_00880	COG2194	sulfuric ester hydrolase activity
CK938_00885	COG0726	polysaccharide deacetylase
CK938_00970	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CK938_00975	COG4856	YbbR-like protein
CK938_00995	COG0596	Alpha beta hydrolase
CK938_01015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CK938_01040	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_01045	COG2011	ABC-type metal ion transport system permease component
CK938_01055	COG1464	Belongs to the NlpA lipoprotein family
CK938_01070	COG0277	FAD linked oxidase domain protein
CK938_01075	COG2271	Major facilitator Superfamily
CK938_01085	COG2814	Major facilitator Superfamily
CK938_01105	COG0601	transmembrane transport
CK938_01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK938_01115	COG0444	Belongs to the ABC transporter superfamily
CK938_01120	COG4608	Belongs to the ABC transporter superfamily
CK938_01125	COG4166	transmembrane transport
CK938_01135	COG2207	Transcriptional regulator
CK938_01150	COG4166	transmembrane transport
CK938_01155	COG4166	transmembrane transport
CK938_01160	COG0656	L-ascorbic acid biosynthetic process
CK938_01165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK938_01175	COG4149	molybdate abc transporter
CK938_01180	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK938_01185	COG1910	domain protein
CK938_01205	COG0697	spore germination
CK938_01225	COG0204	Acyl-transferase
CK938_01235	COG1609	Transcriptional regulator
CK938_01245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_01260	COG0084	hydrolase, TatD family'
CK938_01270	COG5298	Protein conserved in bacteria
CK938_01295	COG0488	(ABC) transporter
CK938_01300	COG4585	Histidine kinase
CK938_01305	COG2197	response regulator
CK938_01310	COG1131	(ABC) transporter
CK938_01315	COG0842	Transport permease protein
CK938_01315	COG1511	domain protein
CK938_01320	COG0842	Transport permease protein
CK938_01335	COG0747	negative chemotaxis
CK938_01340	COG0601	transmembrane transport
CK938_01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK938_01350	COG0444	Belongs to the ABC transporter superfamily
CK938_01355	COG4608	Belongs to the ABC transporter superfamily
CK938_01360	COG0561	phosphatase activity
CK938_01395	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CK938_01400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK938_01415	COG0531	amino acid
CK938_01420	COG2814	Major facilitator Superfamily
CK938_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK938_01440	COG4294	response to UV
CK938_01445	COG0705	Rhomboid family
CK938_01455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK938_01460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK938_01465	COG0864	Transcriptional regulator
CK938_01470	COG2337	Toxic component of a toxin-antitoxin (TA) module
CK938_01475	COG2183	response to ionizing radiation
CK938_01570	COG0802	atpase or kinase
CK938_01575	COG1214	PFAM Peptidase M22, glycoprotease
CK938_01580	COG0456	acetyltransferase
CK938_01590	COG0488	(ABC) transporter
CK938_01605	COG1266	CAAX protease self-immunity
CK938_01625	COG2252	PERMEase
CK938_01635	COG5002	protein histidine kinase activity
CK938_01660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK938_01690	COG2226	methyltransferase
CK938_01710	COG1215	transferase activity, transferring glycosyl groups
CK938_01745	COG2205	protein histidine kinase activity
CK938_01750	COG0745	RESPONSE REGULATOR receiver
CK938_01775	COG0697	spore germination
CK938_01800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CK938_01805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK938_01810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK938_01820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CK938_01835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CK938_01845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK938_01855	COG0151	Belongs to the GarS family
CK938_01885	COG0210	DNA helicase
CK938_01895	COG4851	CamS sex pheromone cAM373 precursor
CK938_01915	COG1335	isochorismatase
CK938_01920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK938_01925	COG2011	ABC-type metal ion transport system permease component
CK938_01930	COG1464	Belongs to the NlpA lipoprotein family
CK938_01945	COG0003	Pfam Anion-transporting ATPase
CK938_01950	COG1846	Transcriptional regulator
CK938_01955	COG4682	membrane
CK938_01975	COG1597	lipid kinase activity
CK938_01980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CK938_01985	COG0546	phosphoglycolate phosphatase activity
CK938_01990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK938_02000	COG1012	belongs to the aldehyde dehydrogenase family
CK938_02005	COG2076	Multidrug Resistance protein
CK938_02010	COG2309	aminopeptidase activity
CK938_02025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_02030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK938_02035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK938_02045	COG5002	protein histidine kinase activity
CK938_02050	COG4807	Protein conserved in bacteria
CK938_02080	COG1473	amidohydrolase
CK938_02095	COG0450	alkyl hydroperoxide reductase
CK938_02100	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CK938_02110	COG0235	Class ii aldolase
CK938_02115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_02125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_02150	COG0166	Belongs to the GPI family
CK938_02195	COG3541	Predicted nucleotidyltransferase
CK938_02200	COG2814	Major facilitator Superfamily
CK938_02205	COG0723	plastoquinol--plastocyanin reductase activity
CK938_02205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK938_02230	COG0765	amino acid transport
CK938_02235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK938_02250	COG0840	transmembrane signaling receptor activity
CK938_02255	COG0840	transmembrane signaling receptor activity
CK938_02260	COG0366	Alpha amylase catalytic
CK938_02265	COG1263	PTS System
CK938_02265	COG2190	(PTS) system
CK938_02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK938_02305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CK938_02310	COG0732	type I restriction modification DNA specificity domain
CK938_02315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CK938_02365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK938_02380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK938_02390	COG1116	anion transmembrane transporter activity
CK938_02400	COG0488	(ABC) transporter
CK938_02450	COG2270	Major facilitator Superfamily
CK938_02480	COG2310	stress, protein
CK938_02485	COG2310	stress, protein
CK938_02490	COG2310	stress, protein
CK938_02495	COG0861	Integral membrane protein TerC family
CK938_02505	COG3853	Toxic anion resistance protein (TelA)
CK938_02520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK938_02530	COG1295	ribonuclease BN
CK938_02540	COG2217	Heavy metal translocating P-type atpase
CK938_02545	COG0697	spore germination
CK938_02555	COG0681	Belongs to the peptidase S26 family
CK938_02565	COG0586	Pfam SNARE associated Golgi protein
CK938_02580	COG3871	stress protein (general stress protein 26)
CK938_02585	COG0387	Pfam Sodium calcium exchanger
CK938_02595	COG0535	radical SAM domain protein
CK938_02615	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CK938_02635	COG3829	transcription factor binding
CK938_02645	COG0833	amino acid
CK938_02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK938_02680	COG2066	Belongs to the glutaminase family
CK938_02685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK938_02685	COG1263	PTS System
CK938_02690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK938_02705	COG0463	Glycosyl transferase, family 2
CK938_02715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK938_02715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK938_02720	COG0463	Glycosyl transferase, family 2
CK938_02735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK938_02755	COG0402	S-adenosylhomocysteine deaminase activity
CK938_02760	COG1090	epimerase
CK938_02790	COG1988	membrane-bound metal-dependent
CK938_02795	COG1194	a g-specific adenine glycosylase
CK938_02820	COG1132	(ABC) transporter
CK938_02825	COG4129	membrane
CK938_02830	COG0070	glutamate synthase
CK938_02830	COG0069	glutamate synthase activity
CK938_02830	COG0067	glutamate synthase
CK938_02840	COG4555	ABC transporter
CK938_02860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK938_02865	COG0735	belongs to the Fur family
CK938_03015	COG4974	Belongs to the 'phage' integrase family
CK938_03045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CK938_03050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK938_03060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK938_03070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK938_03085	COG2766	serine protein kinase
CK938_03110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK938_03120	COG1585	Membrane protein implicated in regulation of membrane protease activity
CK938_03125	COG2268	Band 7 protein
CK938_03135	COG3290	protein histidine kinase activity
CK938_03140	COG4565	transcriptional regulatory protein
CK938_03145	COG2851	Citrate transporter
CK938_03170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CK938_03175	COG3842	ATPase activity
CK938_03180	COG1175	transmembrane transport
CK938_03185	COG0395	ABC-type sugar transport system, permease component
CK938_03195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CK938_03200	COG0745	RESPONSE REGULATOR receiver
CK938_03205	COG5002	protein histidine kinase activity
CK938_03215	COG4990	cell redox homeostasis
CK938_03225	COG0697	spore germination
CK938_03230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_03240	COG5002	protein histidine kinase activity
CK938_03245	COG0745	RESPONSE REGULATOR receiver
CK938_03255	COG0456	acetyltransferase
CK938_03255	COG0454	-acetyltransferase
CK938_03260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK938_03265	COG3383	formate dehydrogenase (NAD+) activity
CK938_03270	COG2427	Protein of unknown function (DUF1641)
CK938_03285	COG0531	amino acid
CK938_03290	COG0640	Transcriptional regulator
CK938_03295	COG2217	Heavy metal translocating P-type atpase
CK938_03300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CK938_03310	COG3227	Zinc metalloprotease (Elastase)
CK938_03330	COG2720	vancomycin resistance protein
CK938_03335	COG1316	TRANSCRIPTIONal
CK938_03340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_03345	COG0346	lactoylglutathione lyase activity
CK938_03350	COG1253	flavin adenine dinucleotide binding
CK938_03355	COG1027	Aspartate ammonia-lyase
CK938_03360	COG1620	l-lactate permease
CK938_03375	COG3104	oligopeptide transport
CK938_03380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_03385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_03400	COG2226	methyltransferase
CK938_03405	COG0156	8-amino-7-oxononanoate synthase activity
CK938_03410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK938_03415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CK938_03425	COG4548	von Willebrand factor, type A
CK938_03430	COG0714	Associated with various cellular activities
CK938_03435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK938_03455	COG0531	amino acid
CK938_03460	COG2188	Transcriptional regulator
CK938_03465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK938_03465	COG1263	PTS System
CK938_03470	COG0366	Alpha amylase catalytic
CK938_03485	COG0697	spore germination
CK938_03490	COG4585	Histidine kinase
CK938_03495	COG2197	response regulator
CK938_03500	COG1404	Belongs to the peptidase S8 family
CK938_03515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK938_03520	COG1115	amino acid carrier protein
CK938_03525	COG1126	abc transporter atp-binding protein
CK938_03530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK938_03535	COG0765	amino acid transport
CK938_03540	COG0765	amino acid transport
CK938_03545	COG0833	amino acid
CK938_03560	COG1595	DNA-templated transcription, initiation
CK938_03570	COG2378	regulation of single-species biofilm formation
CK938_03575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK938_03580	COG5002	protein histidine kinase activity
CK938_03595	COG0659	secondary active sulfate transmembrane transporter activity
CK938_03610	COG0747	negative chemotaxis
CK938_03620	COG0601	transmembrane transport
CK938_03625	COG4608	Belongs to the ABC transporter superfamily
CK938_03635	COG2271	Major facilitator Superfamily
CK938_03640	COG1846	Transcriptional regulator
CK938_03645	COG0477	Major facilitator Superfamily
CK938_03650	COG1609	Transcriptional regulator
CK938_03655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK938_03665	COG1129	ABC transporter
CK938_03670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK938_03675	COG1879	ABC-type sugar transport system periplasmic component
CK938_03680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CK938_03705	COG1063	alcohol dehydrogenase
CK938_03730	COG3568	Endonuclease Exonuclease Phosphatase
CK938_03760	COG0840	transmembrane signaling receptor activity
CK938_03765	COG3584	3D domain protein
CK938_03765	COG3583	domain protein
CK938_03770	COG1476	TRANSCRIPTIONal
CK938_03790	COG3104	oligopeptide transport
CK938_03795	COG1114	Component of the transport system for branched-chain amino acids
CK938_03810	COG1113	amino acid transport
CK938_03815	COG2252	PERMEase
CK938_03830	COG2153	protein acetylation
CK938_03840	COG0475	glutathione-regulated potassium exporter activity
CK938_03840	COG0569	domain protein
CK938_03855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK938_03860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK938_03865	COG0833	amino acid
CK938_03870	COG4990	cell redox homeostasis
CK938_03885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK938_03890	COG0697	spore germination
CK938_03895	COG0531	amino acid
CK938_03910	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CK938_03915	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CK938_03920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CK938_03920	COG1918	ferrous iron import across plasma membrane
CK938_03925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK938_03930	COG0573	inorganic phosphate transmembrane transporter activity
CK938_03935	COG0581	inorganic phosphate transmembrane transporter activity
CK938_03945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK938_04065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CK938_04090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK938_04095	COG1116	anion transmembrane transporter activity
CK938_04100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK938_04105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK938_04110	COG0352	thiamine-phosphate diphosphorylase activity
CK938_04115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK938_04120	COG2104	thiamine diphosphate biosynthetic process
CK938_04130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK938_04135	COG0351	phosphomethylpyrimidine kinase
CK938_04180	COG2205	protein histidine kinase activity
CK938_04185	COG2814	Major facilitator Superfamily
CK938_04190	COG1846	Transcriptional regulator
CK938_04205	COG2252	PERMEase
CK938_04210	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_04235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CK938_04270	COG0778	Nitroreductase
CK938_04305	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CK938_04315	COG0732	type I restriction modification DNA specificity domain
CK938_04325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK938_04325	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CK938_04330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK938_04375	COG2719	SpoVR family
CK938_04395	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK938_04400	COG1937	Protein conserved in bacteria
CK938_04410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK938_04410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_04415	COG0425	Belongs to the sulfur carrier protein TusA family
CK938_04420	COG0425	Belongs to the sulfur carrier protein TusA family
CK938_04430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK938_04430	COG0425	Belongs to the sulfur carrier protein TusA family
CK938_04440	COG2210	Belongs to the sulfur carrier protein TusA family
CK938_04445	COG0730	response to heat
CK938_04455	COG1316	TRANSCRIPTIONal
CK938_04460	COG0604	alcohol dehydrogenase
CK938_04465	COG1283	sodium-dependent phosphate transmembrane transporter activity
CK938_04470	COG2814	Major facilitator Superfamily
CK938_04485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK938_04485	COG3711	transcriptional antiterminator
CK938_04490	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK938_04495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK938_04520	COG1388	LysM domain
CK938_04520	COG3584	3D domain protein
CK938_04525	COG1396	sequence-specific DNA binding
CK938_04535	COG4824	toxin secretion phage lysis holin
CK938_04545	COG0791	NLP P60 protein
CK938_04545	COG1388	LysM domain
CK938_04550	COG3584	3D domain protein
CK938_04550	COG3583	domain protein
CK938_04555	COG0577	efflux transmembrane transporter activity
CK938_04560	COG1136	(ABC) transporter
CK938_04570	COG5522	Integral membrane protein (intg_mem_TP0381)
CK938_04585	COG1114	Component of the transport system for branched-chain amino acids
CK938_04590	COG3546	catalase activity
CK938_04625	COG0586	Pfam SNARE associated Golgi protein
CK938_04660	COG0531	amino acid
CK938_04665	COG0475	glutathione-regulated potassium exporter activity
CK938_04675	COG1737	Transcriptional regulator
CK938_04685	COG1263	PTS System
CK938_04685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK938_04695	COG2259	Doxx family
CK938_04715	COG1522	sequence-specific DNA binding
CK938_04725	COG2076	Multidrug Resistance protein
CK938_04730	COG2076	Multidrug Resistance protein
CK938_04735	COG1309	transcriptional regulator
CK938_04740	COG2814	Major facilitator Superfamily
CK938_04745	COG1733	regulation of RNA biosynthetic process
CK938_04750	COG1846	Transcriptional regulator
CK938_04755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK938_04760	COG0477	Major facilitator Superfamily
CK938_04775	COG2124	cytochrome p450
CK938_04785	COG1063	alcohol dehydrogenase
CK938_04790	COG1733	regulation of RNA biosynthetic process
CK938_04800	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK938_04810	COG2211	Major facilitator Superfamily
CK938_04820	COG0693	protein deglycase activity
CK938_04835	COG0531	amino acid
CK938_04840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK938_04850	COG1012	belongs to the aldehyde dehydrogenase family
CK938_04870	COG1132	(ABC) transporter
CK938_04875	COG1132	(ABC) transporter
CK938_04885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK938_04890	COG0765	amino acid transport
CK938_04895	COG1126	abc transporter atp-binding protein
CK938_04910	COG0189	ligase activity
CK938_04940	COG0028	Belongs to the TPP enzyme family
CK938_04945	COG3527	Alpha-acetolactate decarboxylase
CK938_04955	COG0561	phosphatase activity
CK938_04965	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK938_04965	COG3409	Peptidoglycan-binding domain 1 protein
CK938_04975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK938_04995	COG0659	secondary active sulfate transmembrane transporter activity
CK938_05010	COG0653	protein targeting
CK938_05015	COG2244	polysaccharide biosynthetic process
CK938_05030	COG4196	transglutaminase domain protein
CK938_05045	COG1696	Membrane protein involved in D-alanine export
CK938_05060	COG1024	Enoyl-CoA hydratase
CK938_05080	COG1363	Peptidase, m42
CK938_05095	COG0726	polysaccharide deacetylase
CK938_05100	COG3708	Transcriptional regulator
CK938_05100	COG2207	Transcriptional regulator
CK938_05120	COG4974	Belongs to the 'phage' integrase family
CK938_05165	COG0601	transmembrane transport
CK938_05170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK938_05175	COG0444	Belongs to the ABC transporter superfamily
CK938_05180	COG4608	Belongs to the ABC transporter superfamily
CK938_05190	COG0745	RESPONSE REGULATOR receiver
CK938_05195	COG5002	protein histidine kinase activity
CK938_05240	COG0477	Major facilitator Superfamily
CK938_05245	COG3290	protein histidine kinase activity
CK938_05250	COG4565	transcriptional regulatory protein
CK938_05255	COG3181	Tripartite tricarboxylate transporter family receptor
CK938_05270	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CK938_05295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK938_05310	COG0305	Participates in initiation and elongation during chromosome replication
CK938_05335	COG0477	Major facilitator Superfamily
CK938_05415	COG3711	transcriptional antiterminator
CK938_05420	COG1263	PTS System
CK938_05420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK938_05420	COG2190	(PTS) system
CK938_05425	COG2723	6-phospho-beta-galactosidase activity
CK938_05435	COG1183	phosphatidylcholine synthase activity
CK938_05455	COG2376	Dihydroxyacetone kinase
CK938_05465	COG2376	Dihydroxyacetone kinase
CK938_05565	COG3237	CsbD-like
CK938_05590	COG1191	sigma factor activity
CK938_05600	COG2208	phosphoserine phosphatase activity
CK938_05605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK938_05610	COG5002	protein histidine kinase activity
CK938_05610	COG0784	Response regulator, receiver
CK938_05610	COG2205	protein histidine kinase activity
CK938_05635	COG0393	Putative heavy-metal-binding
CK938_05665	COG2814	Major facilitator Superfamily
CK938_05690	COG0420	3'-5' exonuclease activity
CK938_05695	COG4717	serine-type aminopeptidase activity
CK938_05710	COG0346	lactoylglutathione lyase activity
CK938_05715	COG0346	lactoylglutathione lyase activity
CK938_05720	COG0457	Tetratricopeptide repeat
CK938_05735	COG2267	carboxylic ester hydrolase activity
CK938_05750	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CK938_05755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK938_05765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CK938_05785	COG0772	Belongs to the SEDS family
CK938_05800	COG0477	Major facilitator Superfamily
CK938_05805	COG0477	Major facilitator Superfamily
CK938_05815	COG3973	AAA domain
CK938_05825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK938_05850	COG4980	gas vesicle protein
CK938_05855	COG0537	adenosine 5'-monophosphoramidase activity
CK938_05865	COG1131	(ABC) transporter
CK938_05870	COG4473	ABC transporter
CK938_05935	COG1309	transcriptional regulator
CK938_05945	COG3402	PFAM membrane-flanked domain
CK938_05950	COG3428	Bacterial PH domain
CK938_05980	COG3402	PFAM membrane-flanked domain
CK938_05985	COG3428	Bacterial PH domain
CK938_05995	COG2329	Antibiotic biosynthesis monooxygenase
CK938_06000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK938_06040	COG1309	transcriptional regulator
CK938_06045	COG1511	domain protein
CK938_06065	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CK938_06075	COG2378	regulation of single-species biofilm formation
CK938_06080	COG1609	Transcriptional regulator
CK938_06090	COG1234	tRNA 3'-trailer cleavage
CK938_06095	COG0095	Lipoate-protein ligase
CK938_06110	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_06185	COG1073	alpha beta
CK938_06190	COG1408	metallophosphoesterase
CK938_06195	COG1078	dGTPase activity
CK938_06205	COG1595	DNA-templated transcription, initiation
CK938_06215	COG2207	Transcriptional regulator
CK938_06215	COG3708	Transcriptional regulator
CK938_06230	COG2205	protein histidine kinase activity
CK938_06235	COG0745	RESPONSE REGULATOR receiver
CK938_06260	COG0501	Belongs to the peptidase M48B family
CK938_06265	COG0697	spore germination
CK938_06280	COG0497	DNA recombination
CK938_06285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK938_06290	COG2224	Isocitrate lyase
CK938_06300	COG1278	Cold shock
CK938_06315	COG4903	ComK protein
CK938_06320	COG4585	Histidine kinase
CK938_06325	COG2197	response regulator
CK938_06340	COG0398	Pfam SNARE associated Golgi protein
CK938_06400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK938_06425	COG0367	asparagine synthase
CK938_06435	COG0753	catalase activity
CK938_06440	COG0004	ammonium transporteR
CK938_06470	COG2996	Protein conserved in bacteria
CK938_06475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK938_06485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_06500	COG0561	phosphatase activity
CK938_06515	COG0542	response to heat
CK938_06525	COG2267	carboxylic ester hydrolase activity
CK938_06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK938_06550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK938_06555	COG5504	Zn-dependent protease
CK938_06570	COG0180	Tryptophanyl-tRNA synthetase
CK938_06585	COG4166	transmembrane transport
CK938_06590	COG0601	transmembrane transport
CK938_06595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK938_06600	COG0444	Belongs to the ABC transporter superfamily
CK938_06605	COG4608	Belongs to the ABC transporter superfamily
CK938_06610	COG0534	Mate efflux family protein
CK938_06615	COG4166	transmembrane transport
CK938_06630	COG1393	Belongs to the ArsC family
CK938_06635	COG0861	Integral membrane protein TerC family
CK938_06640	COG4862	establishment of competence for transformation
CK938_06645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK938_06655	COG1164	Oligoendopeptidase f
CK938_06670	COG2346	COG2346, Truncated hemoglobins
CK938_06675	COG4116	CYTH
CK938_06685	COG2357	RelA SpoT domain protein
CK938_06695	COG0564	pseudouridine synthase activity
CK938_06710	COG0772	Belongs to the SEDS family
CK938_06715	COG1216	Glycosyl transferase, family 2
CK938_06735	COG0463	Glycosyl transferase, family 2
CK938_06735	COG0457	Tetratricopeptide repeat
CK938_06755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CK938_06770	COG1091	dTDP-4-dehydrorhamnose reductase activity
CK938_06815	COG2153	protein acetylation
CK938_06825	COG2382	esterase
CK938_06840	COG5492	domain, Protein
CK938_06845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK938_06860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK938_06860	COG0512	Glutamine amidotransferase of anthranilate synthase
CK938_06895	COG1620	l-lactate permease
CK938_06900	COG5634	Uncharacterized conserved protein (DUF2278)
CK938_06965	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK938_06975	COG1476	TRANSCRIPTIONal
CK938_07015	COG2226	methyltransferase
CK938_07030	COG1686	Belongs to the peptidase S11 family
CK938_07035	COG0681	Belongs to the peptidase S26 family
CK938_07070	COG1012	belongs to the aldehyde dehydrogenase family
CK938_07080	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK938_07085	COG1177	transmembrane transport
CK938_07090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK938_07100	COG2409	Drug exporters of the RND superfamily
CK938_07110	COG0564	pseudouridine synthase activity
CK938_07120	COG2340	Cysteine-rich secretory protein family
CK938_07125	COG0247	lactate metabolic process
CK938_07130	COG0277	FAD linked oxidase domain protein
CK938_07135	COG3835	regulator
CK938_07145	COG0745	RESPONSE REGULATOR receiver
CK938_07150	COG5002	protein histidine kinase activity
CK938_07155	COG2186	Transcriptional regulator
CK938_07175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CK938_07185	COG2116	formate transmembrane transporter activity
CK938_07190	COG0861	Integral membrane protein TerC family
CK938_07195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK938_07205	COG2030	dehydratase
CK938_07225	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_07230	COG3243	poly(R)-hydroxyalkanoic acid synthase
CK938_07240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK938_07260	COG1840	ABC-type Fe3 transport system, periplasmic component
CK938_07265	COG3842	ATPase activity
CK938_07290	COG1349	DNA-binding transcription factor activity
CK938_07305	COG0235	Class ii aldolase
CK938_07315	COG2861	carbohydrate metabolic process
CK938_07325	COG3852	Histidine kinase
CK938_07330	COG1846	Transcriptional regulator
CK938_07340	COG2318	DinB family
CK938_07350	COG5002	protein histidine kinase activity
CK938_07360	COG0720	synthase
CK938_07375	COG4873	Protein conserved in bacteria
CK938_07410	COG1780	Probably involved in ribonucleotide reductase function
CK938_07425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK938_07430	COG1725	Transcriptional regulator
CK938_07435	COG1131	(ABC) transporter
CK938_07445	COG1131	(ABC) transporter
CK938_07450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK938_07455	COG1266	CAAX protease self-immunity
CK938_07465	COG1522	sequence-specific DNA binding
CK938_07475	COG1335	isochorismatase
CK938_07485	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK938_07490	COG2070	2-Nitropropane dioxygenase
CK938_07495	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CK938_07505	COG1696	Membrane protein involved in D-alanine export
CK938_07530	COG0716	FMN binding
CK938_07545	COG3173	Aminoglycoside phosphotransferase
CK938_07590	COG1846	Transcriptional regulator
CK938_07600	COG1301	dicarboxylic acid transport
CK938_07605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK938_07610	COG4709	membrane
CK938_07615	COG3874	Sporulation protein YtfJ
CK938_07645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK938_07650	COG0028	Belongs to the TPP enzyme family
CK938_07655	COG0440	acetolactate synthase activity
CK938_07730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK938_07745	COG1183	phosphatidylcholine synthase activity
CK938_07750	COG1368	sulfuric ester hydrolase activity
CK938_07760	COG0019	diaminopimelate decarboxylase activity
CK938_07780	COG0529	Catalyzes the synthesis of activated sulfate
CK938_07785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK938_07805	COG1648	precorrin-2 dehydrogenase activity
CK938_07815	COG0733	neurotransmitter:sodium symporter activity
CK938_07835	COG1757	Na H antiporter
CK938_07850	COG4758	membrane
CK938_07855	COG4585	Histidine kinase
CK938_07860	COG2197	response regulator
CK938_07870	COG1114	Component of the transport system for branched-chain amino acids
CK938_07880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK938_07925	COG0730	response to heat
CK938_07930	COG0306	phosphate transporter
CK938_07935	COG1392	Phosphate transport regulator
CK938_07940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK938_07955	COG3852	Histidine kinase
CK938_07960	COG1801	Protein of unknown function DUF72
CK938_07970	COG0582	viral genome integration into host DNA
CK938_07975	COG5002	protein histidine kinase activity
CK938_07990	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CK938_07990	COG0392	lysyltransferase activity
CK938_08005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK938_08010	COG1686	Belongs to the peptidase S11 family
CK938_08015	COG2715	membrane protein required for spore maturation
CK938_08020	COG0700	Nucleoside recognition
CK938_08025	COG1187	pseudouridine synthase activity
CK938_08035	COG1333	cytochrome c biogenesis protein
CK938_08040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK938_08045	COG0745	RESPONSE REGULATOR receiver
CK938_08050	COG5002	protein histidine kinase activity
CK938_08055	COG2096	Adenosyltransferase
CK938_08060	COG4942	peptidase
CK938_08080	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CK938_08085	COG1141	Ferredoxin
CK938_08095	COG0514	ATP-dependent DNA helicase (RecQ)
CK938_08100	COG1266	CAAX protease self-immunity
CK938_08110	COG1408	metallophosphoesterase
CK938_08120	COG4862	establishment of competence for transformation
CK938_08125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK938_08145	COG0492	ferredoxin-NADP+ reductase activity
CK938_08220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK938_08235	COG0142	geranyltranstransferase activity
CK938_08245	COG0142	geranyltranstransferase activity
CK938_08250	COG0105	UTP biosynthetic process
CK938_08265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CK938_08270	COG0457	Tetratricopeptide repeat
CK938_08290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK938_08295	COG2010	Cytochrome c
CK938_08295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK938_08305	COG4347	Protein of unknown function (DUF1405)
CK938_08320	COG2738	Putative neutral zinc metallopeptidase
CK938_08330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_08340	COG1694	Mazg nucleotide pyrophosphohydrolase
CK938_08355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CK938_08360	COG0438	transferase activity, transferring glycosyl groups
CK938_08400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK938_08400	COG1199	ATP-dependent helicase activity
CK938_08420	COG3935	DnaD domain protein
CK938_08425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK938_08435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK938_08435	COG4499	WXG100 protein secretion system (Wss), protein YukC
CK938_08495	COG0116	Belongs to the methyltransferase superfamily
CK938_08505	COG1199	ATP-dependent helicase activity
CK938_08510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CK938_08520	COG0024	Methionine aminopeptidase
CK938_08530	COG2233	PERMEase
CK938_08535	COG2311	Membrane
CK938_08545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK938_08555	COG0456	acetyltransferase
CK938_08590	COG0754	glutathionylspermidine amidase activity
CK938_08605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK938_08630	COG1335	isochorismatase
CK938_08720	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CK938_08730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CK938_08735	COG1368	sulfuric ester hydrolase activity
CK938_08750	COG3773	Cell wall hydrolase
CK938_08755	COG1404	Belongs to the peptidase S8 family
CK938_08770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_08795	COG5001	Diguanylate cyclase
CK938_08795	COG3300	MHYT domain
CK938_08815	COG2364	Membrane
CK938_08825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CK938_08830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK938_08835	COG2169	Transcriptional regulator
CK938_08845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_08850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_08855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_08860	COG1120	ATPase activity
CK938_08865	COG2819	hydrolase of the alpha beta superfamily
CK938_08885	COG1230	cation diffusion facilitator family transporter
CK938_08895	COG1937	Protein conserved in bacteria
CK938_08900	COG2608	mercury ion transmembrane transporter activity
CK938_08905	COG2217	Heavy metal translocating P-type atpase
CK938_08920	COG2116	formate transmembrane transporter activity
CK938_08925	COG1408	metallophosphoesterase
CK938_08945	COG1113	amino acid transport
CK938_08960	COG2322	membrane
CK938_08965	COG1979	alcohol dehydrogenase
CK938_08970	COG1349	DNA-binding transcription factor activity
CK938_08975	COG1105	Belongs to the carbohydrate kinase PfkB family
CK938_08980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK938_08980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK938_08980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK938_08985	COG3584	3D domain protein
CK938_08985	COG1388	LysM domain
CK938_09020	COG0464	growth
CK938_09025	COG2860	membrane
CK938_09030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK938_09035	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CK938_09040	COG0789	Transcriptional regulator
CK938_09045	COG0174	glutamine synthetase
CK938_09050	COG3944	biosynthesis protein
CK938_09055	COG0489	protein tyrosine kinase activity
CK938_09060	COG1086	Polysaccharide biosynthesis protein
CK938_09065	COG0438	transferase activity, transferring glycosyl groups
CK938_09070	COG0438	transferase activity, transferring glycosyl groups
CK938_09075	COG0463	Glycosyl transferase, family 2
CK938_09075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CK938_09085	COG0438	transferase activity, transferring glycosyl groups
CK938_09095	COG0438	transferase activity, transferring glycosyl groups
CK938_09110	COG1216	Glycosyl transferase, family 2
CK938_09110	COG1442	glycosyl transferase family 8
CK938_09120	COG5434	Belongs to the glycosyl hydrolase 28 family
CK938_09120	COG3420	alginic acid biosynthetic process
CK938_09125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK938_09130	COG0110	maltose O-acetyltransferase activity
CK938_09135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK938_09140	COG0367	asparagine synthase
CK938_09165	COG1132	(ABC) transporter
CK938_09170	COG1695	Transcriptional regulator
CK938_09190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK938_09200	COG0737	Belongs to the 5'-nucleotidase family
CK938_09205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK938_09210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CK938_09215	COG3639	organic phosphonate transmembrane transporter activity
CK938_09245	COG1132	(ABC) transporter
CK938_09250	COG1132	(ABC) transporter
CK938_09270	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK938_09270	COG3409	Peptidoglycan-binding domain 1 protein
CK938_09280	COG0730	response to heat
CK938_09295	COG1346	cytolysis
CK938_09305	COG0583	DNA-binding transcription factor activity
CK938_09315	COG1131	(ABC) transporter
CK938_09340	COG0785	Cytochrome C biogenesis protein
CK938_09345	COG4846	Membrane protein involved in cytochrome C biogenesis
CK938_09390	COG2226	methyltransferase
CK938_09415	COG0010	Belongs to the arginase family
CK938_09420	COG1329	Transcriptional regulator
CK938_09425	COG1902	pentaerythritol trinitrate reductase activity
CK938_09430	COG0069	glutamate synthase activity
CK938_09440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK938_09445	COG0346	lactoylglutathione lyase activity
CK938_09450	COG0400	carboxylic ester hydrolase activity
CK938_09455	COG5002	protein histidine kinase activity
CK938_09470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_09520	COG1396	sequence-specific DNA binding
CK938_09535	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_09540	COG1268	BioY protein
CK938_09545	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_09550	COG0183	Belongs to the thiolase family
CK938_09565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CK938_09575	COG2211	Major facilitator Superfamily
CK938_09595	COG0726	polysaccharide deacetylase
CK938_09605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK938_09615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK938_09625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK938_09655	COG0824	Thioesterase
CK938_09660	COG4841	protein insertion into membrane
CK938_09680	COG0745	RESPONSE REGULATOR receiver
CK938_09685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK938_09690	COG1832	CoA-binding protein
CK938_09700	COG0187	DNA topoisomerase II activity
CK938_09705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK938_09720	COG0673	inositol 2-dehydrogenase activity
CK938_09730	COG1131	(ABC) transporter
CK938_09745	COG1595	DNA-templated transcription, initiation
CK938_09755	COG1316	TRANSCRIPTIONal
CK938_09760	COG1301	dicarboxylic acid transport
CK938_09765	COG4166	transmembrane transport
CK938_09770	COG4166	transmembrane transport
CK938_09775	COG4166	transmembrane transport
CK938_09780	COG2226	methyltransferase
CK938_09825	COG0697	spore germination
CK938_09835	COG3383	formate dehydrogenase (NAD+) activity
CK938_09840	COG2427	Protein of unknown function (DUF1641)
CK938_09845	COG5609	conserved protein (DUF2294)
CK938_09850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK938_09865	COG2116	formate transmembrane transporter activity
CK938_09870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK938_09875	COG0303	'Molybdopterin
CK938_09880	COG0314	molybdopterin synthase activity
CK938_09890	COG0489	protein tyrosine kinase activity
CK938_09905	COG3326	Membrane
CK938_09910	COG2962	Rard protein
CK938_09915	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CK938_09920	COG1657	PFAM Prenyltransferase squalene oxidase
CK938_09930	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_09935	COG1012	belongs to the aldehyde dehydrogenase family
CK938_09945	COG4145	pantothenate transmembrane transporter activity
CK938_09960	COG0165	Argininosuccinate lyase
CK938_09970	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_09990	COG0494	nUDIX hydrolase
CK938_10000	COG0716	FMN binding
CK938_10010	COG1278	Cold shock
CK938_10040	COG2720	vancomycin resistance protein
CK938_10045	COG2514	catechol 2,3-dioxygenase activity
CK938_10060	COG1285	pathogenesis
CK938_10095	COG0277	FAD linked oxidase domain protein
CK938_10100	COG0385	Bile acid
CK938_10110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK938_10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_10140	COG1132	(ABC) transporter
CK938_10145	COG2808	Putative FMN-binding domain
CK938_10155	COG0457	Tetratricopeptide repeat
CK938_10165	COG0604	alcohol dehydrogenase
CK938_10170	COG0640	Transcriptional regulator
CK938_10190	COG0584	glycerophosphoryl diester phosphodiesterase
CK938_10220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK938_10225	COG1164	Oligoendopeptidase f
CK938_10230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CK938_10235	COG1193	negative regulation of DNA recombination
CK938_10250	COG2890	protein-(glutamine-N5) methyltransferase activity
CK938_10260	COG0583	DNA-binding transcription factor activity
CK938_10295	COG3739	integral membrane protein
CK938_10300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_10305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_10310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_10325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK938_10330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CK938_10360	COG2814	Major facilitator Superfamily
CK938_10365	COG1113	amino acid transport
CK938_10375	COG1695	Transcriptional regulator
CK938_10420	COG2072	flavoprotein involved in K transport
CK938_10450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_10465	COG1151	hydroxylamine reductase activity
CK938_10510	COG1309	transcriptional regulator
CK938_10535	COG1191	sigma factor activity
CK938_10545	COG0726	polysaccharide deacetylase
CK938_10565	COG1733	regulation of RNA biosynthetic process
CK938_10570	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK938_10575	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_10590	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_10600	COG0384	phenazine biosynthesis protein PhzF
CK938_10620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_10640	COG1733	regulation of RNA biosynthetic process
CK938_10645	COG1733	regulation of RNA biosynthetic process
CK938_10650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CK938_10655	COG0673	inositol 2-dehydrogenase activity
CK938_10660	COG2188	Transcriptional regulator
CK938_10665	COG1733	regulation of RNA biosynthetic process
CK938_10675	COG1393	Belongs to the ArsC family
CK938_10700	COG0814	amino acid
CK938_10705	COG0346	lactoylglutathione lyase activity
CK938_10725	COG2814	Major facilitator Superfamily
CK938_10730	COG0656	L-ascorbic acid biosynthetic process
CK938_10780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK938_10785	COG1733	regulation of RNA biosynthetic process
CK938_10790	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_10810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK938_10815	COG0604	alcohol dehydrogenase
CK938_10820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CK938_10825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CK938_10835	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CK938_10840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CK938_10850	COG1070	Carbohydrate kinase
CK938_10855	COG2706	6-phosphogluconolactonase activity
CK938_10865	COG3813	Protein conserved in bacteria
CK938_10870	COG1335	isochorismatase
CK938_10875	COG0583	DNA-binding transcription factor activity
CK938_10880	COG1357	PFAM Pentapeptide repeats (8 copies)
CK938_10885	COG0697	spore germination
CK938_10915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK938_10925	COG0789	Transcriptional regulator
CK938_10930	COG1253	flavin adenine dinucleotide binding
CK938_10955	COG0477	Major facilitator Superfamily
CK938_10965	COG0500	methyltransferase
CK938_10985	COG0628	permease
CK938_10995	COG0180	Tryptophanyl-tRNA synthetase
CK938_11000	COG0110	maltose O-acetyltransferase activity
CK938_11005	COG1940	carbohydrate kinase activity
CK938_11010	COG0346	lactoylglutathione lyase activity
CK938_11040	COG1011	Hydrolase
CK938_11065	COG1131	(ABC) transporter
CK938_11075	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_11100	COG0778	Nitroreductase
CK938_11120	COG1733	regulation of RNA biosynthetic process
CK938_11135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK938_11160	COG0789	Transcriptional regulator
CK938_11165	COG1309	transcriptional regulator
CK938_11170	COG2814	Major facilitator Superfamily
CK938_11180	COG1288	antiporter activity
CK938_11185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK938_11200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CK938_11235	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK938_11245	COG2031	fatty acid transporter
CK938_11265	COG1309	transcriptional regulator
CK938_11270	COG2076	Multidrug Resistance protein
CK938_11290	COG1131	(ABC) transporter
CK938_11295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK938_11310	COG2814	Major facilitator Superfamily
CK938_11315	COG1846	Transcriptional regulator
CK938_11330	COG0477	Major facilitator Superfamily
CK938_11360	COG3409	Peptidoglycan-binding domain 1 protein
CK938_11360	COG5632	N-Acetylmuramoyl-L-alanine amidase
CK938_11385	COG2207	Transcriptional regulator
CK938_11385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_11395	COG0662	Cupin 2, conserved barrel domain protein
CK938_11415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK938_11430	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK938_11445	COG0583	DNA-binding transcription factor activity
CK938_11455	COG1139	Iron-sulfur cluster binding protein
CK938_11460	COG1556	Lactate utilization protein
CK938_11465	COG2271	Major facilitator Superfamily
CK938_11470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_11480	COG5002	protein histidine kinase activity
CK938_11480	COG3850	Histidine kinase
CK938_11505	COG0577	efflux transmembrane transporter activity
CK938_11525	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CK938_11565	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CK938_11625	COG4895	conserved protein (DUF2196)
CK938_11635	COG2814	Major facilitator Superfamily
CK938_11675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK938_11685	COG0346	lactoylglutathione lyase activity
CK938_11710	COG1522	sequence-specific DNA binding
CK938_11715	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_11750	COG1309	transcriptional regulator
CK938_11755	COG2814	Major facilitator Superfamily
CK938_11775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK938_11775	COG3320	Male sterility
CK938_11785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK938_11800	COG0640	Transcriptional regulator
CK938_11805	COG0346	lactoylglutathione lyase activity
CK938_11810	COG0798	PFAM Bile acid sodium symporter
CK938_11825	COG4154	Belongs to the RbsD FucU family
CK938_11835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK938_11845	COG0235	Class ii aldolase
CK938_11850	COG1070	Carbohydrate kinase
CK938_11860	COG3347	Dehydrogenase
CK938_11860	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_11870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_11905	COG0577	efflux transmembrane transporter activity
CK938_11910	COG1136	(ABC) transporter
CK938_11915	COG4641	Protein conserved in bacteria
CK938_11920	COG2267	carboxylic ester hydrolase activity
CK938_11930	COG1575	Belongs to the MenA family. Type 1 subfamily
CK938_11940	COG0697	spore germination
CK938_11960	COG5609	conserved protein (DUF2294)
CK938_11965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK938_11975	COG0288	reversible hydration of carbon dioxide
CK938_11980	COG0415	Belongs to the DNA photolyase family
CK938_12030	COG0598	Magnesium transport protein CorA
CK938_12035	COG0753	catalase activity
CK938_12040	COG0737	Belongs to the 5'-nucleotidase family
CK938_12045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK938_12055	COG1063	alcohol dehydrogenase
CK938_12075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_12085	COG0574	Belongs to the PEP-utilizing enzyme family
CK938_12085	COG3848	Pyruvate phosphate dikinase
CK938_12120	COG1960	acyl-CoA dehydrogenase activity
CK938_12135	COG0640	Transcriptional regulator
CK938_12140	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK938_12155	COG1414	Transcriptional regulator
CK938_12160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CK938_12165	COG1984	allophanate hydrolase subunit 2
CK938_12240	COG4335	DNA alkylation repair
CK938_12250	COG0833	amino acid
CK938_12260	COG0730	response to heat
CK938_12305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_12325	COG0456	acetyltransferase
CK938_12355	COG1136	(ABC) transporter
CK938_12390	COG1846	Transcriptional regulator
CK938_12395	COG0778	Nitroreductase
CK938_12430	COG3403	YqcI/YcgG family
CK938_12435	COG1280	lysine exporter protein (LysE YggA)
CK938_12445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CK938_12460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK938_12480	COG0714	Associated with various cellular activities
CK938_12500	COG0346	lactoylglutathione lyase activity
CK938_12525	COG3279	Response regulator of the LytR AlgR family
CK938_12535	COG4377	Putative membrane peptidase family (DUF2324)
CK938_12550	COG3655	Transcriptional regulator
CK938_12560	COG1785	Belongs to the alkaline phosphatase family
CK938_12570	COG3239	Fatty acid desaturase
CK938_12575	COG1690	Belongs to the RtcB family
CK938_12580	COG0833	amino acid
CK938_12590	COG1414	Transcriptional regulator
CK938_12595	COG4187	Peptidase family M20/M25/M40
CK938_12600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK938_12620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_12635	COG2329	Antibiotic biosynthesis monooxygenase
CK938_12660	COG1070	Carbohydrate kinase
CK938_12665	COG2390	Transcriptional regulator
CK938_12710	COG1388	LysM domain
CK938_12710	COG3584	3D domain protein
CK938_12755	COG1605	Chorismate mutase
CK938_12755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CK938_12770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CK938_12775	COG0287	Prephenate dehydrogenase
CK938_12790	COG1309	transcriptional regulator
CK938_12795	COG1033	growth of symbiont in host cell
CK938_12795	COG2409	Drug exporters of the RND superfamily
CK938_12810	COG0488	(ABC) transporter
CK938_12820	COG1368	sulfuric ester hydrolase activity
CK938_12825	COG0861	Integral membrane protein TerC family
CK938_12830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK938_12840	COG3037	sugar-specific permease SgaT UlaA
CK938_12850	COG0726	polysaccharide deacetylase
CK938_12855	COG4912	Dna alkylation repair
CK938_12880	COG0697	spore germination
CK938_12900	COG2746	aminoglycoside 3-N-acetyltransferase activity
CK938_12945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK938_12950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK938_12955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK938_12970	COG0628	permease
CK938_13025	COG1131	(ABC) transporter
CK938_13040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CK938_13050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK938_13055	COG0436	Aminotransferase
CK938_13095	COG2226	methyltransferase
CK938_13110	COG2261	transglycosylase associated protein
CK938_13130	COG0477	Major facilitator Superfamily
CK938_13130	COG2814	Major facilitator Superfamily
CK938_13135	COG4533	DNA binding
CK938_13140	COG0789	Transcriptional regulator
CK938_13145	COG1664	Polymer-forming cytoskeletal
CK938_13155	COG2814	Major facilitator Superfamily
CK938_13200	COG1307	EDD domain protein, DegV family
CK938_13240	COG0745	RESPONSE REGULATOR receiver
CK938_13245	COG5002	protein histidine kinase activity
CK938_13310	COG4948	Mandelate Racemase Muconate Lactonizing
CK938_13320	COG4166	transmembrane transport
CK938_13325	COG0519	Catalyzes the synthesis of GMP from XMP
CK938_13330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CK938_13345	COG0586	Pfam SNARE associated Golgi protein
CK938_13350	COG1078	dGTPase activity
CK938_13400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK938_13405	COG3938	Belongs to the proline racemase family
CK938_13415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK938_13420	COG1012	belongs to the aldehyde dehydrogenase family
CK938_13425	COG1115	amino acid carrier protein
CK938_13430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK938_13445	COG3397	chitin binding
CK938_13465	COG4637	Psort location Cytoplasmic, score
CK938_13500	COG0514	ATP-dependent DNA helicase (RecQ)
CK938_13505	COG2105	PFAM AIG2 family protein
CK938_13525	COG3973	AAA domain
CK938_13570	COG2333	competence protein COMEC
CK938_13570	COG0658	competence protein
CK938_13580	COG2315	Protein conserved in bacteria
CK938_13585	COG2226	methyltransferase
CK938_13590	COG2205	protein histidine kinase activity
CK938_13610	COG1819	glycosyl
CK938_13615	COG3397	chitin binding
CK938_13620	COG2153	protein acetylation
CK938_13625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CK938_13640	COG0740	serine-type endopeptidase activity
CK938_13650	COG4175	Glycine betaine
CK938_13650	COG0517	IMP dehydrogenase activity
CK938_13655	COG4176	ABC-type proline glycine betaine transport system permease component
CK938_13680	COG0494	nUDIX hydrolase
CK938_13690	COG0456	acetyltransferase
CK938_13690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK938_13695	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_13705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK938_13710	COG0022	dehydrogenase e1 component
CK938_13715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK938_13720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK938_13740	COG1349	DNA-binding transcription factor activity
CK938_13760	COG3284	Transcriptional regulator
CK938_13795	COG1309	transcriptional regulator
CK938_13825	COG3409	Peptidoglycan-binding domain 1 protein
CK938_13825	COG3773	Cell wall hydrolase
CK938_13830	COG2959	enzyme of heme biosynthesis
CK938_13845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_13885	COG0201	protein transport
CK938_13895	COG3227	Zinc metalloprotease (Elastase)
CK938_13900	COG1523	belongs to the glycosyl hydrolase 13 family
CK938_13950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK938_13990	COG0322	excinuclease ABC activity
CK938_14030	COG4667	esterase of the alpha-beta hydrolase superfamily
CK938_14050	COG3878	Protein conserved in bacteria
CK938_14095	COG2207	Transcriptional regulator
CK938_14095	COG3708	Transcriptional regulator
CK938_14115	COG0592	DNA-directed DNA polymerase activity
CK938_14120	COG2816	NAD+ diphosphatase activity
CK938_14135	COG2223	nitrite transmembrane transporter activity
CK938_14160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK938_14170	COG0697	spore germination
CK938_14175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_14190	COG0584	glycerophosphoryl diester phosphodiesterase
CK938_14230	COG0596	Alpha beta hydrolase
CK938_14235	COG1819	glycosyl
CK938_14240	COG0076	glutamate decarboxylase activity
CK938_14245	COG0693	protein deglycase activity
CK938_14290	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_14305	COG0671	phosphoesterase, PA-phosphatase related
CK938_14310	COG0604	alcohol dehydrogenase
CK938_14315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK938_14325	COG2205	protein histidine kinase activity
CK938_14350	COG1794	racemase activity, acting on amino acids and derivatives
CK938_14355	COG1819	glycosyl
CK938_14365	COG5002	protein histidine kinase activity
CK938_14375	COG0561	phosphatase activity
CK938_14410	COG2124	cytochrome p450
CK938_14510	COG3728	DNA packaging
CK938_14510	COG5484	DNA packaging
CK938_14515	COG3728	DNA packaging
CK938_14515	COG5484	DNA packaging
CK938_14580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK938_14595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_14600	COG0460	homoserine dehydrogenase
CK938_14615	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CK938_14635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK938_14640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK938_14645	COG2323	membrane
CK938_14665	COG2368	4-hydroxyphenylacetate
CK938_14675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_14690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK938_14705	COG2226	methyltransferase
CK938_14715	COG2814	Major facilitator Superfamily
CK938_14725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK938_14750	COG3227	Zinc metalloprotease (Elastase)
CK938_14770	COG2910	NAD(P)H-binding
CK938_14775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK938_14805	COG1686	Belongs to the peptidase S11 family
CK938_14810	COG0572	uridine kinase
CK938_14835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK938_14840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK938_14845	COG1024	Enoyl-CoA hydratase
CK938_14850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK938_14855	COG0511	ligase activity, forming carbon-carbon bonds
CK938_14860	COG0439	Biotin carboxylase
CK938_14865	COG1960	acyl-CoA dehydrogenase activity
CK938_14885	COG1309	transcriptional regulator
CK938_14895	COG1131	(ABC) transporter
CK938_14905	COG1408	metallophosphoesterase
CK938_14910	COG2367	Beta-lactamase
CK938_14930	COG1595	DNA-templated transcription, initiation
CK938_14950	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK938_15010	COG3961	Belongs to the TPP enzyme family
CK938_15020	COG0500	methyltransferase
CK938_15020	COG3615	Tellurite resistance protein tehB
CK938_15025	COG0577	efflux transmembrane transporter activity
CK938_15025	COG1136	(ABC) transporter
CK938_15040	COG1309	transcriptional regulator
CK938_15080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_15125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CK938_15195	COG2971	BadF BadG BcrA BcrD
CK938_15220	COG1649	PFAM Uncharacterised BCR, COG1649
CK938_15250	COG1595	DNA-templated transcription, initiation
CK938_15295	COG1396	sequence-specific DNA binding
CK938_15310	COG2226	methyltransferase
CK938_15315	COG2132	Multicopper oxidase
CK938_15330	COG0582	viral genome integration into host DNA
CK938_15370	COG1132	(ABC) transporter
CK938_15375	COG1132	(ABC) transporter
CK938_15390	COG2258	MOSC domain
CK938_15395	COG0583	DNA-binding transcription factor activity
CK938_15410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK938_15415	COG0583	DNA-binding transcription factor activity
CK938_15420	COG2814	Major facilitator Superfamily
CK938_15425	COG1846	Transcriptional regulator
CK938_15435	COG0561	phosphatase activity
CK938_15440	COG0010	Belongs to the arginase family
CK938_15455	COG1278	Cold shock
CK938_15465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_15480	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CK938_15500	COG1247	-acetyltransferase
CK938_15530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_15570	COG0028	Belongs to the TPP enzyme family
CK938_15585	COG2814	Major facilitator Superfamily
CK938_15600	COG1136	(ABC) transporter
CK938_15605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CK938_15610	COG1187	pseudouridine synthase activity
CK938_15615	COG2329	Antibiotic biosynthesis monooxygenase
CK938_15645	COG1115	amino acid carrier protein
CK938_15650	COG2318	DinB family
CK938_15660	COG0776	regulation of translation
CK938_15675	COG2814	Major facilitator Superfamily
CK938_15680	COG3251	PFAM MbtH domain protein
CK938_15685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK938_15690	COG3433	isochorismatase activity
CK938_15690	COG1535	isochorismatase
CK938_15695	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK938_15700	COG1169	isochorismate synthase
CK938_15705	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_15715	COG2223	nitrite transmembrane transporter activity
CK938_15750	COG0420	3'-5' exonuclease activity
CK938_15765	COG1024	Enoyl-CoA hydratase
CK938_15770	COG1280	lysine exporter protein (LysE YggA)
CK938_15780	COG2084	Dehydrogenase
CK938_15785	COG1960	acyl-CoA dehydrogenase activity
CK938_15790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CK938_15795	COG2079	MmgE PrpD family protein
CK938_15800	COG0372	Belongs to the citrate synthase family
CK938_15805	COG4841	protein insertion into membrane
CK938_15810	COG2814	Major facilitator Superfamily
CK938_15820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK938_15820	COG4499	WXG100 protein secretion system (Wss), protein YukC
CK938_15860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK938_15900	COG1595	DNA-templated transcription, initiation
CK938_15940	COG3728	DNA packaging
CK938_15940	COG5484	DNA packaging
CK938_15955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK938_15960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK938_15965	COG0671	phosphoesterase, PA-phosphatase related
CK938_15970	COG4326	sporulation control protein
CK938_15975	COG0515	serine threonine protein kinase
CK938_15975	COG3064	Membrane
CK938_15975	COG4991	sh3 domain protein
CK938_16010	COG1509	lysine 2,3-aminomutase activity
CK938_16015	COG3829	transcription factor binding
CK938_16020	COG0456	acetyltransferase
CK938_16025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK938_16030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK938_16035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK938_16040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK938_16060	COG5506	Protein of unknown function (DUF1694)
CK938_16065	COG1012	belongs to the aldehyde dehydrogenase family
CK938_16070	COG1253	flavin adenine dinucleotide binding
CK938_16105	COG1174	glycine betaine transport
CK938_16110	COG0517	IMP dehydrogenase activity
CK938_16110	COG1125	glycine betaine transport
CK938_16145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CK938_16170	COG1064	alcohol dehydrogenase
CK938_16185	COG2197	response regulator
CK938_16190	COG4585	Histidine kinase
CK938_16190	COG2203	Gaf domain
CK938_16195	COG0668	transmembrane transport
CK938_16200	COG0071	Belongs to the small heat shock protein (HSP20) family
CK938_16205	COG1051	belongs to the nudix hydrolase family
CK938_16210	COG1335	isochorismatase
CK938_16225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK938_16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_16250	COG0367	asparagine synthase
CK938_16255	COG0071	Belongs to the small heat shock protein (HSP20) family
CK938_16260	COG1999	signal sequence binding
CK938_16265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CK938_16270	COG1307	EDD domain protein, DegV family
CK938_16285	COG0805	protein transport
CK938_16295	COG1272	protein, Hemolysin III
CK938_16300	COG0204	Acyl-transferase
CK938_16310	COG0768	penicillin binding
CK938_16330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK938_16345	COG0546	phosphoglycolate phosphatase activity
CK938_16355	COG4473	ABC transporter
CK938_16360	COG1131	(ABC) transporter
CK938_16370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK938_16375	COG0456	acetyltransferase
CK938_16385	COG1794	racemase activity, acting on amino acids and derivatives
CK938_16390	COG1454	alcohol dehydrogenase
CK938_16395	COG2610	gluconate transmembrane transporter activity
CK938_16420	COG0733	neurotransmitter:sodium symporter activity
CK938_16470	COG1674	ftsk spoiiie
CK938_16490	COG0017	Asparaginyl-tRNA synthetase
CK938_16500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK938_16520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CK938_16550	COG2521	methyltransferase
CK938_16550	COG2136	Putative SAM-dependent methyltransferase
CK938_16565	COG1413	lyase activity
CK938_16580	COG0629	single-stranded DNA binding
CK938_16595	COG0488	(ABC) transporter
CK938_16600	COG1418	mRNA catabolic process
CK938_16620	COG2359	stage V sporulation protein S
CK938_16645	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CK938_16650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK938_16655	COG2146	nitrite reductase [NAD(P)H] activity
CK938_16660	COG1587	Uroporphyrinogen-III synthase
CK938_16660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK938_16670	COG1648	precorrin-2 dehydrogenase activity
CK938_16690	COG2223	nitrite transmembrane transporter activity
CK938_16700	COG0314	molybdopterin synthase activity
CK938_16705	COG0303	'Molybdopterin
CK938_16710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK938_16715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK938_16720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK938_16725	COG2181	nitrate reductase activity
CK938_16730	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CK938_16735	COG1140	nitrate reductase beta subunit
CK938_16740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CK938_16755	COG0714	Associated with various cellular activities
CK938_16760	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CK938_16765	COG1305	Transglutaminase-like
CK938_16770	COG0386	Belongs to the glutathione peroxidase family
CK938_16780	COG0426	domain, Protein
CK938_16780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK938_16795	COG1595	DNA-templated transcription, initiation
CK938_16800	COG0604	alcohol dehydrogenase
CK938_16810	COG0346	lactoylglutathione lyase activity
CK938_16815	COG1082	Xylose isomerase domain protein TIM barrel
CK938_16835	COG2226	methyltransferase
CK938_16860	COG3874	Sporulation protein YtfJ
CK938_16885	COG0456	acetyltransferase
CK938_16915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK938_16920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_16925	COG1819	glycosyl
CK938_16945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK938_16955	COG0561	phosphatase activity
CK938_17035	COG0640	Transcriptional regulator
CK938_17040	COG0798	PFAM Bile acid sodium symporter
CK938_17085	COG2211	Major facilitator Superfamily
CK938_17090	COG0154	amidase activity
CK938_17100	COG1876	peptidase activity
CK938_17110	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK938_17130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK938_17135	COG1114	Component of the transport system for branched-chain amino acids
CK938_17150	COG1253	flavin adenine dinucleotide binding
CK938_17155	COG2839	Protein conserved in bacteria
CK938_17160	COG0702	epimerase
CK938_17175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK938_17185	COG1607	acyl-coa hydrolase
CK938_17190	COG3689	TIGRFAM TIGR03943 family protein
CK938_17195	COG0701	Predicted permease
CK938_17205	COG2244	polysaccharide biosynthetic process
CK938_17210	COG0586	Pfam SNARE associated Golgi protein
CK938_17215	COG1051	belongs to the nudix hydrolase family
CK938_17220	COG5337	Spore coat protein CotH
CK938_17230	COG0406	alpha-ribazole phosphatase activity
CK938_17245	COG4166	transmembrane transport
CK938_17255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK938_17265	COG0702	epimerase
CK938_17275	COG3443	Belongs to the bacterial solute-binding protein 9 family
CK938_17275	COG0803	Belongs to the bacterial solute-binding protein 9 family
CK938_17290	COG0456	acetyltransferase
CK938_17295	COG0523	cobalamin synthesis protein
CK938_17300	COG4989	oxidoreductase activity
CK938_17305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_17310	COG1231	oxidoreductase activity
CK938_17320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK938_17335	COG0783	Belongs to the Dps family
CK938_17340	COG3949	Membrane
CK938_17360	COG0840	transmembrane signaling receptor activity
CK938_17390	COG2814	Major facilitator Superfamily
CK938_17395	COG0667	Aldo Keto reductase
CK938_17400	COG0640	Transcriptional regulator
CK938_17405	COG1404	Belongs to the peptidase S8 family
CK938_17410	COG2002	toxin-antitoxin pair type II binding
CK938_17415	COG0577	efflux transmembrane transporter activity
CK938_17450	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK938_17465	COG1279	arginine transmembrane transporter activity
CK938_17470	COG2814	Major facilitator Superfamily
CK938_17485	COG1247	-acetyltransferase
CK938_17490	COG1285	pathogenesis
CK938_17500	COG0726	polysaccharide deacetylase
CK938_17510	COG1316	TRANSCRIPTIONal
CK938_17535	COG0460	homoserine dehydrogenase
CK938_17555	COG0726	polysaccharide deacetylase
CK938_17565	COG0300	oxidoreductase activity
CK938_17575	COG5002	protein histidine kinase activity
CK938_17580	COG0745	RESPONSE REGULATOR receiver
CK938_17585	COG1132	(ABC) transporter
CK938_17595	COG0791	NLP P60 protein
CK938_17595	COG1388	LysM domain
CK938_17610	COG1686	Belongs to the peptidase S11 family
CK938_17650	COG1216	Glycosyl transferase, family 2
CK938_17660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK938_17665	COG4988	ABC transporter
CK938_17670	COG1294	oxidase, subunit
CK938_17675	COG1271	oxidase subunit
CK938_17695	COG1942	4-Oxalocrotonate Tautomerase
CK938_17725	COG0411	ABC transporter
CK938_17735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK938_17740	COG2030	dehydratase
CK938_17745	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_17755	COG0523	cobalamin synthesis protein
CK938_17760	COG1231	oxidoreductase activity
CK938_17770	COG0628	permease
CK938_17785	COG0778	Nitroreductase
CK938_17790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK938_17795	COG1959	2 iron, 2 sulfur cluster binding
CK938_17800	COG0583	DNA-binding transcription factor activity
CK938_17805	COG0697	spore germination
CK938_17810	COG4549	nuclear export factor GLE1
CK938_17815	COG2372	response to copper ion
CK938_17815	COG1276	copper resistance
CK938_17825	COG1114	Component of the transport system for branched-chain amino acids
CK938_17865	COG0006	proline dipeptidase activity
CK938_17875	COG4846	Membrane protein involved in cytochrome C biogenesis
CK938_17885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CK938_17890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_17900	COG2390	Transcriptional regulator
CK938_17930	COG0531	amino acid
CK938_17935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK938_17950	COG1914	H( )-stimulated, divalent metal cation uptake system
CK938_17970	COG0745	RESPONSE REGULATOR receiver
CK938_17975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_18020	COG4166	transmembrane transport
CK938_18025	COG1131	(ABC) transporter
CK938_18030	COG1073	alpha beta
CK938_18050	COG0427	acetyl-CoA hydrolase
CK938_18055	COG3279	Response regulator of the LytR AlgR family
CK938_18065	COG3384	dioxygenase
CK938_18070	COG2814	Major facilitator Superfamily
CK938_18095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK938_18105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CK938_18110	COG0440	acetolactate synthase activity
CK938_18115	COG0028	Belongs to the TPP enzyme family
CK938_18120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK938_18125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK938_18150	COG2323	membrane
CK938_18155	COG5566	PFAM Mor transcription activator
CK938_18165	COG0733	neurotransmitter:sodium symporter activity
CK938_18170	COG2244	polysaccharide biosynthetic process
CK938_18185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK938_18190	COG2223	nitrite transmembrane transporter activity
CK938_18195	COG4166	transmembrane transport
CK938_18200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK938_18210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK938_18215	COG0477	Major facilitator Superfamily
CK938_18265	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK938_18270	COG1051	belongs to the nudix hydrolase family
CK938_18305	COG3620	sequence-specific DNA binding
CK938_18330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK938_18335	COG0784	Response regulator, receiver
CK938_18340	COG4191	Histidine kinase
CK938_18345	COG0281	malic enzyme
CK938_18350	COG1027	Aspartate ammonia-lyase
CK938_18360	COG0528	UMP kinase activity
CK938_18365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK938_18380	COG1131	(ABC) transporter
CK938_18420	COG2733	membrane
CK938_18460	COG3340	Belongs to the peptidase S51 family
CK938_18470	COG0534	Mate efflux family protein
CK938_18490	COG0114	fumarate hydratase activity
CK938_18495	COG1757	Na H antiporter
CK938_18500	COG1216	Glycosyl transferase, family 2
CK938_18500	COG0438	transferase activity, transferring glycosyl groups
CK938_18505	COG0697	spore germination
CK938_18510	COG1802	Transcriptional regulator
CK938_18540	COG0367	asparagine synthase
CK938_18550	COG1846	Transcriptional regulator
CK938_18570	COG0406	alpha-ribazole phosphatase activity
CK938_18580	COG1686	Belongs to the peptidase S11 family
CK938_18595	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_18615	COG1234	tRNA 3'-trailer cleavage
CK938_18620	COG1177	transmembrane transport
CK938_18625	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK938_18630	COG3842	ATPase activity
CK938_18660	COG2329	Antibiotic biosynthesis monooxygenase
CK938_18705	COG4786	Flagellar basal body rod
CK938_18710	COG1419	protein localization to endoplasmic reticulum
CK938_18715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK938_18720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK938_18730	COG1987	bacterial-type flagellum assembly
CK938_18735	COG1338	Plays a role in the flagellum-specific transport system
CK938_18745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK938_18745	COG1776	CheC inhibitor of MCP methylation
CK938_18750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK938_18765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK938_18785	COG0835	chemotaxis
CK938_18785	COG0784	Response regulator, receiver
CK938_18820	COG1157	protein secretion by the type III secretion system
CK938_18830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK938_18835	COG1766	The M ring may be actively involved in energy transduction
CK938_18840	COG1677	Flagellar hook-basal body complex protein FliE
CK938_18845	COG1558	bacterial-type flagellum-dependent cell motility
CK938_18850	COG1815	bacterial-type flagellum-dependent cell motility
CK938_18870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK938_18875	COG1256	bacterial-type flagellum assembly
CK938_18895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK938_18910	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK938_18910	COG1776	CheC inhibitor of MCP methylation
CK938_18915	COG0643	Histidine kinase
CK938_18915	COG2198	Histidine kinase
CK938_18920	COG2201	protein-glutamate methylesterase activity
CK938_18925	COG1360	Flagellar Motor Protein
CK938_18940	COG1923	regulation of RNA biosynthetic process
CK938_18970	COG2814	Major facilitator Superfamily
CK938_19000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK938_19005	COG2323	membrane
CK938_19015	COG4978	Transcriptional regulator
CK938_19015	COG0789	Transcriptional regulator
CK938_19020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CK938_19025	COG0475	glutathione-regulated potassium exporter activity
CK938_19040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK938_19045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK938_19050	COG3162	membrane
CK938_19065	COG1280	lysine exporter protein (LysE YggA)
CK938_19070	COG3403	YqcI/YcgG family
CK938_19105	COG0328	RNA-DNA hybrid ribonuclease activity
CK938_19125	COG0454	-acetyltransferase
CK938_19150	COG0726	polysaccharide deacetylase
CK938_19155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK938_19155	COG1017	nitric oxide dioxygenase activity
CK938_19170	COG1846	Transcriptional regulator
CK938_19175	COG2207	Transcriptional regulator
CK938_19175	COG3708	Transcriptional regulator
CK938_19190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK938_19205	COG0640	Transcriptional regulator
CK938_19210	COG0210	DNA helicase
CK938_19215	COG0210	DNA helicase
CK938_19250	COG4550	Control of competence regulator ComK, YlbF/YmcA
CK938_19260	COG1013	pyruvate-flavodoxin oxidoreductase activity
CK938_19265	COG0674	pyruvate-flavodoxin oxidoreductase activity
CK938_19265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CK938_19275	COG2359	stage V sporulation protein S
CK938_19280	COG1692	metallophosphoesterase
CK938_19305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK938_19310	COG1426	Protein conserved in bacteria
CK938_19325	COG0300	oxidoreductase activity
CK938_19330	COG0612	Peptidase, M16
CK938_19335	COG0612	Peptidase, M16
CK938_19360	COG2188	Transcriptional regulator
CK938_19370	COG1674	ftsk spoiiie
CK938_19380	COG0740	serine-type endopeptidase activity
CK938_19385	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CK938_19395	COG0527	aspartate kinase activity
CK938_19400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK938_19405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK938_19410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK938_19415	COG1873	PFAM PRC-barrel domain
CK938_19420	COG0612	Peptidase, M16
CK938_19425	COG0726	polysaccharide deacetylase
CK938_19440	COG0196	riboflavin kinase activity
CK938_19455	COG1550	Protein conserved in bacteria
CK938_19465	COG1358	cellular component organization or biogenesis
CK938_19470	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CK938_19475	COG0195	Participates in both transcription termination and antitermination
CK938_19500	COG0750	zinc metalloprotease
CK938_19510	COG4589	Belongs to the CDS family
CK938_19525	COG0528	UMP kinase activity
CK938_19555	COG4974	Belongs to the 'phage' integrase family
CK938_19565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK938_19570	COG0758	DNA mediated transformation
CK938_19575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CK938_19615	COG1837	Belongs to the UPF0109 family
CK938_19625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK938_19635	COG0552	protein localization to endoplasmic reticulum
CK938_19640	COG1196	nuclear chromosome segregation
CK938_19655	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_19660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CK938_19675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK938_19680	COG1461	Dihydroxyacetone kinase
CK938_19685	COG1302	Protein conserved in bacteria
CK938_19700	COG1564	THIamine pyrophosphokinase
CK938_19705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK938_19715	COG0515	serine threonine protein kinase
CK938_19715	COG2815	serine threonine protein kinase
CK938_19720	COG0631	protein serine/threonine phosphatase activity
CK938_19730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK938_19730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK938_19740	COG0242	peptide deformylase activity
CK938_19745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK938_19750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK938_19760	COG0194	GDP metabolic process
CK938_19770	COG1561	YicC-like family, N-terminal region
CK938_19775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CK938_19790	COG0006	proline dipeptidase activity
CK938_19815	COG3069	C4-dicarboxylate transmembrane transporter activity
CK938_19880	COG0564	pseudouridine synthase activity
CK938_19900	COG3599	regulation of cell shape
CK938_19905	COG2302	S4 RNA-binding domain
CK938_19910	COG0762	integral membrane protein
CK938_19920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CK938_19930	COG1873	PFAM PRC-barrel domain
CK938_19935	COG1191	sigma factor activity
CK938_19940	COG1191	sigma factor activity
CK938_19950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK938_19955	COG0849	cell division
CK938_19960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK938_19975	COG0772	Belongs to the SEDS family
CK938_19990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK938_19995	COG0768	penicillin binding
CK938_20005	COG4839	cell division protein FtsL
CK938_20020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK938_20040	COG1399	metal-binding, possibly nucleic acid-binding protein
CK938_20050	COG3480	Lon protease (S16) C-terminal proteolytic domain
CK938_20055	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK938_20060	COG3314	Sporulation integral membrane protein YlbJ
CK938_20070	COG0742	ribosomal rna small subunit methyltransferase
CK938_20085	COG3679	Belongs to the UPF0342 family
CK938_20090	COG0406	alpha-ribazole phosphatase activity
CK938_20105	COG2340	Cysteine-rich secretory protein family
CK938_20120	COG3344	reverse transcriptase
CK938_20130	COG3336	cytochrome c oxidase
CK938_20165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CK938_20175	COG0772	Belongs to the SEDS family
CK938_20185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CK938_20190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CK938_20200	COG4896	Protein conserved in bacteria
CK938_20225	COG0483	inositol monophosphate 1-phosphatase activity
CK938_20245	COG1982	Orn Lys Arg decarboxylase major
CK938_20295	COG0022	dehydrogenase e1 component
CK938_20300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK938_20310	COG0242	peptide deformylase activity
CK938_20315	COG0561	phosphatase activity
CK938_20330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CK938_20335	COG0569	domain protein
CK938_20355	COG0583	DNA-binding transcription factor activity
CK938_20360	COG0517	IMP dehydrogenase activity
CK938_20370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CK938_20380	COG4703	Protein of unknown function (DUF1797)
CK938_20395	COG2200	EAL domain
CK938_20400	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_20405	COG1408	metallophosphoesterase
CK938_20420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CK938_20460	COG2814	Major facilitator Superfamily
CK938_20490	COG3209	COG3209 Rhs family protein
CK938_20505	COG2205	protein histidine kinase activity
CK938_20515	COG0436	Aminotransferase
CK938_20520	COG1609	Transcriptional regulator
CK938_20525	COG3833	ABC-type maltose transport systems, permease component
CK938_20530	COG1175	transmembrane transport
CK938_20535	COG2182	Extracellular solute-binding protein
CK938_20545	COG0366	Alpha amylase catalytic
CK938_20550	COG3842	ATPase activity
CK938_20590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK938_20595	COG0183	Belongs to the thiolase family
CK938_20630	COG1695	Transcriptional regulator
CK938_20635	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_20655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK938_20660	COG0436	Aminotransferase
CK938_20695	COG2084	Dehydrogenase
CK938_20705	COG3706	GGDEF domain
CK938_20710	COG0778	Nitroreductase
CK938_20740	COG3711	transcriptional antiterminator
CK938_20760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK938_20790	COG1547	Domain of unknown function (DUF309)
CK938_20795	COG0456	acetyltransferase
CK938_20805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK938_20810	COG4086	secreted protein
CK938_20815	COG0561	phosphatase activity
CK938_20820	COG0697	spore germination
CK938_20835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK938_20860	COG0733	neurotransmitter:sodium symporter activity
CK938_20880	COG1686	Belongs to the peptidase S11 family
CK938_20890	COG1725	Transcriptional regulator
CK938_20895	COG1131	(ABC) transporter
CK938_20920	COG1846	Transcriptional regulator
CK938_20935	COG0598	Magnesium transport protein CorA
CK938_20960	COG4974	Belongs to the 'phage' integrase family
CK938_20970	COG0735	belongs to the Fur family
CK938_20975	COG1300	Membrane
CK938_20995	COG0667	Aldo Keto reductase
CK938_21000	COG0656	L-ascorbic acid biosynthetic process
CK938_21005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK938_21005	COG0456	acetyltransferase
CK938_21015	COG4085	toxin activity
CK938_21015	COG0737	Belongs to the 5'-nucleotidase family
CK938_21015	COG1525	nuclease
CK938_21025	COG0596	Alpha beta hydrolase
CK938_21030	COG2056	Na+-H+ antiporter family
CK938_21035	COG1609	Transcriptional regulator
CK938_21040	COG0456	acetyltransferase
CK938_21045	COG1073	alpha beta
CK938_21060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK938_21060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK938_21065	COG0307	riboflavin synthase, alpha
CK938_21090	COG4106	trans-aconitate 2-methyltransferase activity
CK938_21095	COG2226	methyltransferase
CK938_21095	COG1073	alpha beta
CK938_21110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK938_21130	COG0737	Belongs to the 5'-nucleotidase family
CK938_21140	COG1522	sequence-specific DNA binding
CK938_21185	COG5444	nuclease activity
CK938_21195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK938_21225	COG0300	oxidoreductase activity
CK938_21230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_21235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK938_21240	COG1760	l-serine dehydratase
CK938_21245	COG1760	l-serine dehydratase
CK938_21270	COG1285	pathogenesis
CK938_21275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK938_21285	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK938_21290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_21305	COG1376	ErfK ybiS ycfS ynhG family protein
CK938_21310	COG4129	membrane
CK938_21315	COG1126	abc transporter atp-binding protein
CK938_21320	COG0765	amino acid transport
CK938_21325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK938_21345	COG2323	membrane
CK938_21350	COG0772	Belongs to the SEDS family
CK938_21360	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK938_21365	COG0022	dehydrogenase e1 component
CK938_21370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK938_21375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK938_21385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK938_21390	COG0280	phosphate acetyltransferase
CK938_21400	COG3290	protein histidine kinase activity
CK938_21400	COG3829	transcription factor binding
CK938_21410	COG0584	glycerophosphoryl diester phosphodiesterase
CK938_21415	COG3093	addiction module antidote protein HigA
CK938_21420	COG0745	RESPONSE REGULATOR receiver
CK938_21430	COG0750	zinc metalloprotease
CK938_21435	COG0497	DNA recombination
CK938_21445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CK938_21455	COG0142	geranyltranstransferase activity
CK938_21480	COG1302	Protein conserved in bacteria
CK938_21485	COG0439	Biotin carboxylase
CK938_21490	COG0511	ligase activity, forming carbon-carbon bonds
CK938_21535	COG3854	ATPases associated with a variety of cellular activities
CK938_21560	COG0006	proline dipeptidase activity
CK938_21575	COG3872	metal-dependent enzyme
CK938_21585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK938_21620	COG0095	Lipoate-protein ligase
CK938_21625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK938_21635	COG1609	Transcriptional regulator
CK938_21645	COG2076	Multidrug Resistance protein
CK938_21650	COG2076	Multidrug Resistance protein
CK938_21690	COG1131	(ABC) transporter
CK938_21695	COG1725	Transcriptional regulator
CK938_21725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK938_21785	COG4970	Tfp pilus assembly protein FimT
CK938_21795	COG1459	type II secretion system
CK938_21800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK938_21855	COG0646	methionine synthase
CK938_21855	COG1410	methionine synthase
CK938_21860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK938_21860	COG0646	methionine synthase
CK938_21865	COG0626	cystathionine gamma-synthase activity
CK938_21870	COG0626	cystathionine gamma-synthase activity
CK938_21890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_21900	COG1940	carbohydrate kinase activity
CK938_21905	COG4483	Protein conserved in bacteria
CK938_21910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK938_21920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK938_21925	COG0704	Plays a role in the regulation of phosphate uptake
CK938_21930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK938_21935	COG0581	inorganic phosphate transmembrane transporter activity
CK938_21940	COG0573	inorganic phosphate transmembrane transporter activity
CK938_21945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK938_21955	COG0477	Major facilitator Superfamily
CK938_21960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK938_21985	COG0735	belongs to the Fur family
CK938_21990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK938_21995	COG1121	(ABC) transporter
CK938_22000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_22030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK938_22035	COG2384	SAM-dependent methyltransferase
CK938_22045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK938_22050	COG0358	DNA primase activity
CK938_22075	COG0517	IMP dehydrogenase activity
CK938_22090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CK938_22095	COG0295	cytidine deaminase activity
CK938_22100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK938_22110	COG1480	7TM receptor with intracellular HD hydrolase
CK938_22115	COG1702	phosphate starvation-inducible protein PhoH
CK938_22135	COG1610	YqeY-like protein
CK938_22145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK938_22150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK938_22180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK938_22185	COG1733	regulation of RNA biosynthetic process
CK938_22210	COG1466	dna polymerase III delta subunit
CK938_22220	COG2333	competence protein COMEC
CK938_22220	COG0658	competence protein
CK938_22225	COG2131	deaminase
CK938_22230	COG1596	polysaccharide export
CK938_22230	COG1555	photosystem II stabilization
CK938_22235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK938_22240	COG2226	methyltransferase
CK938_22245	COG0799	negative regulation of ribosome biogenesis
CK938_22250	COG1713	HD superfamily hydrolase involved in NAD metabolism
CK938_22260	COG1534	Rna-binding protein
CK938_22270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK938_22275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CK938_22290	COG1191	sigma factor activity
CK938_22310	COG0778	Nitroreductase
CK938_22315	COG2357	RelA SpoT domain protein
CK938_22325	COG1785	Belongs to the alkaline phosphatase family
CK938_22335	COG2267	carboxylic ester hydrolase activity
CK938_22370	COG1404	Belongs to the peptidase S8 family
CK938_22375	COG3186	Phenylalanine-4-hydroxylase
CK938_22385	COG2514	catechol 2,3-dioxygenase activity
CK938_22390	COG2259	Doxx family
CK938_22430	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CK938_22445	COG1454	alcohol dehydrogenase
CK938_22445	COG1012	belongs to the aldehyde dehydrogenase family
CK938_22450	COG0626	cystathionine gamma-synthase activity
CK938_22455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK938_22480	COG0768	penicillin binding
CK938_22510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK938_22540	COG0628	permease
CK938_22560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK938_22575	COG1104	cysteine desulfurase activity
CK938_22580	COG1959	2 iron, 2 sulfur cluster binding
CK938_22585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK938_22600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK938_22630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK938_22640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK938_22640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CK938_22645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK938_22650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK938_22650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK938_22660	COG2244	polysaccharide biosynthetic process
CK938_22665	COG2323	membrane
CK938_22675	COG1862	Preprotein translocase
CK938_22705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CK938_22715	COG0697	spore germination
CK938_22720	COG0640	Transcriptional regulator
CK938_22745	COG0157	Belongs to the NadC ModD family
CK938_22750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CK938_22755	COG1104	cysteine desulfurase activity
CK938_22760	COG1827	regulation of RNA biosynthetic process
CK938_22765	COG2258	MOSC domain
CK938_22770	COG0077	Prephenate dehydratase
CK938_22775	COG0577	efflux transmembrane transporter activity
CK938_22780	COG0577	efflux transmembrane transporter activity
CK938_22785	COG1136	(ABC) transporter
CK938_22790	COG5002	protein histidine kinase activity
CK938_22795	COG0745	RESPONSE REGULATOR receiver
CK938_22805	COG3290	protein histidine kinase activity
CK938_22815	COG2868	ribosomal protein
CK938_22825	COG1530	ribonuclease E activity
CK938_22830	COG1994	Peptidase M50
CK938_22835	COG0739	heme binding
CK938_22840	COG2894	cell division
CK938_22855	COG1792	Involved in formation and maintenance of cell shape
CK938_22860	COG1077	Cell shape determining protein MreB Mrl
CK938_22885	COG0285	dihydrofolate synthase activity
CK938_22900	COG1388	LysM domain
CK938_22910	COG0113	porphobilinogen synthase activity
CK938_22915	COG1587	Uroporphyrinogen-III synthase
CK938_22925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK938_22935	COG1846	Transcriptional regulator
CK938_22940	COG1764	response to oxidative stress
CK938_22955	COG1067	ATP-dependent peptidase activity
CK938_22955	COG0470	DNA polymerase III
CK938_23005	COG0622	Phosphoesterase
CK938_23020	COG5401	PFAM Sporulation and spore germination
CK938_23030	COG2814	Major facilitator Superfamily
CK938_23040	COG1309	transcriptional regulator
CK938_23050	COG2197	response regulator
CK938_23055	COG2233	PERMEase
CK938_23065	COG0402	S-adenosylhomocysteine deaminase activity
CK938_23070	COG0402	S-adenosylhomocysteine deaminase activity
CK938_23090	COG0444	Belongs to the ABC transporter superfamily
CK938_23095	COG4608	Belongs to the ABC transporter superfamily
CK938_23100	COG3275	phosphorelay sensor kinase activity
CK938_23105	COG3279	Response regulator of the LytR AlgR family
CK938_23115	COG1983	PspC domain protein
CK938_23120	COG1396	sequence-specific DNA binding
CK938_23125	COG0697	spore germination
CK938_23135	COG1959	2 iron, 2 sulfur cluster binding
CK938_23140	COG1668	transmembrane transport
CK938_23145	COG4152	abc transporter atp-binding protein
CK938_23150	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CK938_23155	COG1360	Flagellar Motor Protein
CK938_23160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK938_23165	COG1876	peptidase activity
CK938_23170	COG0824	Thioesterase
CK938_23175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK938_23180	COG1053	succinate dehydrogenase
CK938_23185	COG2009	succinate dehydrogenase
CK938_23190	COG1719	4-vinyl reductase, 4VR
CK938_23200	COG3118	belongs to the thioredoxin family
CK938_23205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CK938_23210	COG2086	electron transfer activity
CK938_23215	COG1024	Enoyl-CoA hydratase
CK938_23220	COG1309	transcriptional regulator
CK938_23225	COG0318	PFAM AMP-dependent synthetase and ligase
CK938_23245	COG2318	DinB family
CK938_23270	COG1131	(ABC) transporter
CK938_23275	COG2205	protein histidine kinase activity
CK938_23280	COG0745	RESPONSE REGULATOR receiver
CK938_23290	COG4895	conserved protein (DUF2196)
CK938_23295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK938_23310	COG4509	Sortase family
CK938_23315	COG1120	ATPase activity
CK938_23330	COG5386	Cell surface protein
CK938_23335	COG5386	Cell surface protein
CK938_23340	COG1114	Component of the transport system for branched-chain amino acids
CK938_23345	COG1187	pseudouridine synthase activity
CK938_23360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK938_23360	COG1796	DNA polymerase
CK938_23365	COG1286	toxin biosynthetic process
CK938_23410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK938_23420	COG1418	mRNA catabolic process
CK938_23430	COG2814	Major facilitator Superfamily
CK938_23435	COG1566	PFAM secretion protein HlyD family protein
CK938_23440	COG1309	transcriptional regulator
CK938_23445	COG1363	Peptidase, m42
CK938_23465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CK938_23470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CK938_23480	COG1484	DNA-dependent DNA replication
CK938_23485	COG3611	Membrane attachment protein
CK938_23495	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CK938_23505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK938_23510	COG0237	dephospho-CoA kinase activity
CK938_23515	COG1971	Probably functions as a manganese efflux pump
CK938_23525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK938_23525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK938_23530	COG5002	protein histidine kinase activity
CK938_23535	COG0745	RESPONSE REGULATOR receiver
CK938_23560	COG0538	isocitrate dehydrogenase activity
CK938_23565	COG0372	Belongs to the citrate synthase family
CK938_23580	COG0628	permease
CK938_23585	COG3030	protein affecting phage T7 exclusion by the F plasmid
CK938_23610	COG1725	Transcriptional regulator
CK938_23615	COG0281	malic enzyme
CK938_23620	COG0587	DNA-directed DNA polymerase activity
CK938_23640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CK938_23660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK938_23670	COG4109	DRTGG domain
CK938_23685	COG0006	proline dipeptidase activity
CK938_23720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_23725	COG0662	Cupin 2, conserved barrel domain protein
CK938_23765	COG1028	Short-chain dehydrogenase reductase Sdr
CK938_23770	COG0589	response to stress
CK938_23820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_23845	COG0827	DNA restriction-modification system
CK938_23850	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CK938_23855	COG3874	Sporulation protein YtfJ
CK938_23865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK938_23870	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CK938_23880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK938_23895	COG1104	cysteine desulfurase activity
CK938_23905	COG0583	DNA-binding transcription factor activity
CK938_23910	COG0697	spore germination
CK938_23915	COG1309	transcriptional regulator
CK938_23920	COG1956	GAF domain-containing protein
CK938_23925	COG0626	cystathionine gamma-synthase activity
CK938_23960	COG1595	DNA-templated transcription, initiation
CK938_23975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK938_23980	COG0454	-acetyltransferase
CK938_23985	COG0517	IMP dehydrogenase activity
CK938_23990	COG0123	including yeast histone deacetylase and acetoin utilization protein
CK938_24005	COG0745	RESPONSE REGULATOR receiver
CK938_24015	COG0666	response to abiotic stimulus
CK938_24055	COG1609	Transcriptional regulator
CK938_24065	COG4851	CamS sex pheromone cAM373 precursor
CK938_24070	COG3118	belongs to the thioredoxin family
CK938_24080	COG2309	aminopeptidase activity
CK938_24100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_24105	COG0697	spore germination
CK938_24110	COG0789	Transcriptional regulator
CK938_24115	COG1695	Transcriptional regulator
CK938_24135	COG1674	ftsk spoiiie
CK938_24145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK938_24155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK938_24160	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CK938_24165	COG1363	Peptidase, m42
CK938_24175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_24190	COG0510	thiamine kinase activity
CK938_24195	COG1523	belongs to the glycosyl hydrolase 13 family
CK938_24210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK938_24215	COG1349	DNA-binding transcription factor activity
CK938_24220	COG1187	pseudouridine synthase activity
CK938_24225	COG2244	polysaccharide biosynthetic process
CK938_24230	COG2081	HI0933 family
CK938_24240	COG2814	Major facilitator Superfamily
CK938_24250	COG3832	glyoxalase III activity
CK938_24275	COG1329	Transcriptional regulator
CK938_24300	COG0314	molybdopterin synthase activity
CK938_24305	COG1763	Mo-molybdopterin cofactor biosynthetic process
CK938_24310	COG0303	'Molybdopterin
CK938_24320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK938_24325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK938_24345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK938_24355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK938_24395	COG2814	Major facilitator Superfamily
CK938_24400	COG0475	glutathione-regulated potassium exporter activity
CK938_24405	COG0490	domain, Protein
CK938_24410	COG0582	viral genome integration into host DNA
CK938_24425	COG1136	(ABC) transporter
CK938_24445	COG1242	4 iron, 4 sulfur cluster binding
CK938_24450	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CK938_24465	COG1794	racemase activity, acting on amino acids and derivatives
CK938_24490	COG2267	carboxylic ester hydrolase activity
CK938_24495	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK938_24500	COG0671	phosphoesterase, PA-phosphatase related
CK938_24505	COG0438	transferase activity, transferring glycosyl groups
CK938_24515	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK938_24580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK938_24585	COG5002	protein histidine kinase activity
CK938_24590	COG4191	Histidine kinase
CK938_24595	COG2267	carboxylic ester hydrolase activity
CK938_24600	COG1368	sulfuric ester hydrolase activity
CK938_24620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK938_24625	COG1116	anion transmembrane transporter activity
CK938_24630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK938_24650	COG0494	nUDIX hydrolase
CK938_24680	COG0288	reversible hydration of carbon dioxide
CK938_24685	COG1271	oxidase subunit
CK938_24690	COG1294	oxidase, subunit
CK938_24715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_24740	COG1842	Phage shock protein A
CK938_24775	COG5002	protein histidine kinase activity
CK938_24780	COG0745	RESPONSE REGULATOR receiver
CK938_24810	COG1597	lipid kinase activity
CK938_24825	COG0577	efflux transmembrane transporter activity
CK938_24830	COG1136	(ABC) transporter
CK938_24855	COG0586	Pfam SNARE associated Golgi protein
CK938_24875	COG0577	efflux transmembrane transporter activity
CK938_24880	COG1136	(ABC) transporter
CK938_24885	COG3708	Transcriptional regulator
CK938_24885	COG2207	Transcriptional regulator
CK938_24890	COG5658	integral membrane protein
CK938_24895	COG0640	Transcriptional regulator
CK938_24900	COG0745	RESPONSE REGULATOR receiver
CK938_24905	COG2205	protein histidine kinase activity
CK938_24910	COG0577	efflux transmembrane transporter activity
CK938_24915	COG0577	efflux transmembrane transporter activity
CK938_24920	COG1136	(ABC) transporter
CK938_24925	COG0577	efflux transmembrane transporter activity
CK938_24965	COG3964	amidohydrolase
CK938_24985	COG4948	Mandelate Racemase Muconate Lactonizing
CK938_24995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CK938_25000	COG0596	Alpha beta hydrolase
CK938_25010	COG1169	isochorismate synthase
CK938_25015	COG1575	Belongs to the MenA family. Type 1 subfamily
CK938_25020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK938_25025	COG1278	Cold shock
CK938_25045	COG0058	SHG alpha-glucan phosphorylase activity
CK938_25075	COG1404	Belongs to the peptidase S8 family
CK938_25085	COG0039	L-malate dehydrogenase activity
CK938_25185	COG0544	peptidyl-prolyl cis-trans isomerase activity
CK938_25225	COG1285	pathogenesis
CK938_25230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK938_25250	COG2155	Conserved Protein
CK938_25255	COG1098	S1 RNA binding domain
CK938_25260	COG0436	Aminotransferase
CK938_25265	COG1522	sequence-specific DNA binding
CK938_25270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK938_25275	COG2267	carboxylic ester hydrolase activity
CK938_25285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CK938_25300	COG5018	Exonuclease
CK938_25305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK938_25325	COG0423	glycine-tRNA ligase activity
CK938_25330	COG2050	protein possibly involved in aromatic compounds catabolism
CK938_25340	COG1268	BioY protein
CK938_25345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK938_25350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK938_25365	COG3584	3D domain protein
CK938_25380	COG1252	NADH dehydrogenase
CK938_25390	COG3708	Transcriptional regulator
CK938_25415	COG1683	Conserved Protein
CK938_25435	COG0316	Belongs to the HesB IscA family
CK938_25450	COG1252	NADH dehydrogenase
CK938_25460	COG2274	protein secretion by the type I secretion system
CK938_25465	COG0390	transport system, permease component
CK938_25470	COG2824	Alkylphosphonate utilization operon protein PhnA
CK938_25510	COG4837	Protein of unknown function (DUF1462)
CK938_25515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CK938_25525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK938_25530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK938_25540	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK938_25550	COG0647	UMP catabolic process
CK938_25560	COG2445	Protein of unknown function DUF86
CK938_25565	COG1494	fructose-1,6-bisphosphatase
CK938_25585	COG4470	Protein conserved in bacteria
CK938_25595	COG0789	Transcriptional regulator
CK938_25600	COG4377	Putative membrane peptidase family (DUF2324)
CK938_25625	COG0739	heme binding
CK938_25635	COG3377	Domain of unknown function (DUF1805)
CK938_25640	COG0737	Belongs to the 5'-nucleotidase family
CK938_25650	COG0719	Fe-S assembly protein
CK938_25655	COG0822	iron-sulfur transferase activity
CK938_25660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK938_25665	COG0719	Fe-S assembly protein
CK938_25670	COG0396	ATPase activity
CK938_25675	COG1464	Belongs to the NlpA lipoprotein family
CK938_25680	COG1464	Belongs to the NlpA lipoprotein family
CK938_25685	COG2011	ABC-type metal ion transport system permease component
CK938_25700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK938_25705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CK938_25715	COG1393	Belongs to the ArsC family
CK938_25790	COG1309	transcriptional regulator
CK938_25795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK938_25800	COG1960	acyl-CoA dehydrogenase activity
CK938_25805	COG0183	Belongs to the thiolase family
CK938_25810	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK938_25810	COG1024	Enoyl-CoA hydratase
CK938_25825	COG1686	Belongs to the peptidase S11 family
CK938_25855	COG0011	TIGRFAM Protein of
CK938_25860	COG0840	transmembrane signaling receptor activity
CK938_25880	COG2814	Major facilitator Superfamily
CK938_25885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CK938_25895	COG0531	amino acid
CK938_25920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CK938_25960	COG0586	Pfam SNARE associated Golgi protein
CK938_25970	COG1376	ErfK ybiS ycfS ynhG family protein
CK938_25975	COG0745	RESPONSE REGULATOR receiver
CK938_25980	COG5002	protein histidine kinase activity
CK938_26005	COG0840	transmembrane signaling receptor activity
CK938_26010	COG2151	metal-sulfur cluster biosynthetic enzyme
CK938_26015	COG3227	Zinc metalloprotease (Elastase)
CK938_26020	COG1741	Belongs to the pirin family
CK938_26035	COG0475	glutathione-regulated potassium exporter activity
CK938_26040	COG0490	domain, Protein
CK938_26050	COG1115	amino acid carrier protein
CK938_26055	COG0783	Belongs to the Dps family
CK938_26075	COG1611	Belongs to the LOG family
CK938_26095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_26100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_26105	COG1115	amino acid carrier protein
CK938_26110	COG1115	amino acid carrier protein
CK938_26115	COG2910	NAD(P)H-binding
CK938_26135	COG0656	L-ascorbic acid biosynthetic process
CK938_26140	COG2814	Major facilitator Superfamily
CK938_26145	COG1733	regulation of RNA biosynthetic process
CK938_26155	COG1252	NADH dehydrogenase
CK938_26160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK938_26175	COG0840	transmembrane signaling receptor activity
CK938_26175	COG3290	protein histidine kinase activity
CK938_26185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CK938_26200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK938_26205	COG3223	Belongs to the PsiE family
CK938_26245	COG5002	protein histidine kinase activity
CK938_26250	COG0745	RESPONSE REGULATOR receiver
CK938_26255	COG1136	(ABC) transporter
CK938_26275	COG1136	(ABC) transporter
CK938_26315	COG0557	exoribonuclease II activity
CK938_26320	COG1647	Serine aminopeptidase, S33
CK938_26325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK938_26330	COG1346	cytolysis
CK938_26365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK938_26380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CK938_26405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK938_26420	COG2323	membrane
CK938_26430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK938_26440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CK938_26450	COG1051	belongs to the nudix hydrolase family
CK938_26460	COG0492	ferredoxin-NADP+ reductase activity
CK938_26465	COG0457	Tetratricopeptide repeat
CK938_26470	COG0110	maltose O-acetyltransferase activity
CK938_26490	COG1950	PFAM Membrane protein of
CK938_26500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK938_26515	COG0789	Transcriptional regulator
CK938_26550	COG0583	DNA-binding transcription factor activity
CK938_26560	COG0655	NAD(P)H dehydrogenase (quinone) activity
CK938_26575	COG1132	(ABC) transporter
CK938_26585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK938_26590	COG0793	Belongs to the peptidase S41A family
CK938_26590	COG3409	Peptidoglycan-binding domain 1 protein
CK938_26595	COG2177	Part of the ABC transporter FtsEX involved in
CK938_26600	COG2884	Cell division ATP-binding protein ftsE
CK938_26610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CK938_26630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK938_26635	COG1278	Cold shock
CK938_26640	COG1040	competence protein
CK938_26645	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CK938_26650	COG0791	NLP P60 protein
CK938_26655	COG1733	regulation of RNA biosynthetic process
CK938_26665	COG1307	EDD domain protein, DegV family
CK938_26670	COG1739	Uncharacterized protein family UPF0029
CK938_26675	COG1316	TRANSCRIPTIONal
CK938_26680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CK938_26685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CK938_26690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CK938_26700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CK938_26700	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CK938_26720	COG1486	melibiose metabolic process
CK938_26725	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK938_26730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK938_26740	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CK938_26755	COG1447	Phosphotransferase system cellobiose-specific component IIA
CK938_26765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CK938_26770	COG1301	dicarboxylic acid transport
CK938_26785	COG0346	lactoylglutathione lyase activity
CK938_26790	COG1511	domain protein
CK938_26795	COG0583	DNA-binding transcription factor activity
CK938_26800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CK938_26810	COG1271	oxidase subunit
CK938_26815	COG1294	oxidase, subunit
CK938_26820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK938_26830	COG1620	l-lactate permease
CK938_26840	COG2389	metal-binding protein
CK938_26855	COG1368	sulfuric ester hydrolase activity
CK938_26870	COG0791	NLP P60 protein
CK938_26870	COG1388	LysM domain
CK938_26875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK938_26885	COG1215	transferase activity, transferring glycosyl groups
CK938_26895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK938_26905	COG3584	3D domain protein
CK938_26905	COG1388	LysM domain
CK938_26915	COG4715	Zinc finger, swim domain protein
CK938_26920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK938_26950	COG1191	sigma factor activity
CK938_26965	COG0577	efflux transmembrane transporter activity
CK938_26970	COG1136	(ABC) transporter
CK938_27005	COG5002	protein histidine kinase activity
CK938_27010	COG0745	RESPONSE REGULATOR receiver
CK938_27015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK938_27030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK938_27035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CK938_27040	COG1215	transferase activity, transferring glycosyl groups
CK938_27050	COG1216	Glycosyl transferase, family 2
CK938_27050	COG1442	glycosyl transferase family 8
CK938_27060	COG1215	transferase activity, transferring glycosyl groups
CK938_27085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK938_27090	COG4464	protein tyrosine phosphatase activity
CK938_27095	COG0489	protein tyrosine kinase activity
CK938_27100	COG3944	biosynthesis protein
CK938_27105	COG0489	protein tyrosine kinase activity
CK938_27120	COG4195	phage-related replication protein
CK938_27150	COG1609	Transcriptional regulator
CK938_27160	COG0739	heme binding
CK938_27175	COG3279	Response regulator of the LytR AlgR family
CK938_27180	COG2385	sporulation resulting in formation of a cellular spore
CK938_27195	COG4836	Membrane
CK938_27200	COG1007	ATP synthesis coupled electron transport
CK938_27205	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK938_27210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK938_27220	COG0839	Belongs to the complex I subunit 6 family
CK938_27240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK938_27250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK938_27255	COG5001	Diguanylate cyclase
CK938_27255	COG3300	MHYT domain
CK938_27310	COG0356	it plays a direct role in the translocation of protons across the membrane
CK938_27345	COG0698	ribose 5-phosphate isomerase
CK938_27360	COG2190	(PTS) system
CK938_27365	COG2259	Doxx family
CK938_27370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK938_27390	COG0009	L-threonylcarbamoyladenylate synthase
CK938_27405	COG2890	protein-(glutamine-N5) methyltransferase activity
CK938_27410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CK938_27430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CK938_27440	COG1494	fructose-1,6-bisphosphatase
CK938_27450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK938_27465	COG4821	SIS domain
CK938_27485	COG1960	acyl-CoA dehydrogenase activity
CK938_27490	COG1960	acyl-CoA dehydrogenase activity
CK938_27495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK938_27500	COG0183	Belongs to the thiolase family
CK938_27505	COG0247	lactate metabolic process
CK938_27505	COG2181	nitrate reductase activity
CK938_27510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK938_27520	COG3300	MHYT domain
CK938_27520	COG5001	Diguanylate cyclase
CK938_27545	COG2197	response regulator
CK938_27550	COG4585	Histidine kinase
CK938_27555	COG0842	Transport permease protein
CK938_27560	COG1131	(ABC) transporter
CK938_27565	COG0024	Methionine aminopeptidase
CK938_27575	COG2234	aminopeptidase activity
CK938_27610	COG1595	DNA-templated transcription, initiation
CK938_27625	COG4506	Protein conserved in bacteria
CK938_27630	COG1619	proteins homologs of microcin C7 resistance protein MccF
CK938_27655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CK938_27660	COG2814	Major facilitator Superfamily
CK938_27665	COG0789	Transcriptional regulator
CK938_27670	COG0584	glycerophosphoryl diester phosphodiesterase
CK938_27675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK938_27685	COG1994	Peptidase M50
CK938_27695	COG1078	dGTPase activity
CK938_27700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK938_27705	COG1120	ATPase activity
CK938_27710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_27715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK938_27735	COG0095	Lipoate-protein ligase
CK938_27740	COG0280	phosphate acetyltransferase
CK938_27755	COG3773	Cell wall hydrolase
CK938_27765	COG2363	Small membrane protein
CK938_27775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK938_27780	COG2233	PERMEase
CK938_27785	COG0561	phosphatase activity
CK938_27790	COG2814	Major facilitator Superfamily
CK938_27800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CK938_27805	COG1131	(ABC) transporter
CK938_27810	COG2755	lipolytic protein G-D-S-L family
CK938_27815	COG1609	Transcriptional regulator
CK938_27825	COG0460	homoserine dehydrogenase
CK938_27840	COG1011	Hydrolase
CK938_27845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK938_27855	COG2197	response regulator
CK938_27860	COG4585	Histidine kinase
CK938_27860	COG2203	Gaf domain
CK938_27865	COG0351	phosphomethylpyrimidine kinase
CK938_27870	COG3706	GGDEF domain
CK938_27875	COG2879	small protein
CK938_27880	COG1966	Carbon starvation protein
CK938_27885	COG3279	Response regulator of the LytR AlgR family
CK938_27890	COG0477	Major facilitator Superfamily
CK938_27905	COG0438	transferase activity, transferring glycosyl groups
CK938_27920	COG0840	transmembrane signaling receptor activity
CK938_27930	COG1607	acyl-coa hydrolase
CK938_27935	COG1216	Glycosyl transferase, family 2
CK938_27950	COG1216	Glycosyl transferase, family 2
CK938_27965	COG0488	(ABC) transporter
CK938_27970	COG1309	transcriptional regulator
CK938_27975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK938_27980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK938_27980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK938_27990	COG0628	permease
CK938_28005	COG3279	Response regulator of the LytR AlgR family
CK938_28010	COG3275	phosphorelay sensor kinase activity
CK938_28015	COG2814	Major facilitator Superfamily
CK938_28020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK938_28025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CK938_28035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK938_28055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK938_28060	COG1272	protein, Hemolysin III
CK938_28080	COG1164	Oligoendopeptidase f
CK938_28100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK938_28105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CK938_28110	COG4853	Protein conserved in bacteria
CK938_28115	COG4863	YycH protein
CK938_28120	COG5002	protein histidine kinase activity
CK938_28125	COG0745	RESPONSE REGULATOR receiver
CK938_28155	COG0305	Participates in initiation and elongation during chromosome replication
CK938_28165	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CK938_28170	COG4241	membrane
CK938_28190	COG0012	GTP binding
CK938_28195	COG4481	Protein conserved in bacteria
CK938_28200	COG0668	transmembrane transport
CK938_28210	COG1475	DNA binding
CK938_28215	COG1192	Involved in chromosome partitioning
CK938_28240	COG1847	R3H domain protein
CK938_28245	COG0706	membrane insertase activity
CK938_28300	COG0071	Belongs to the small heat shock protein (HSP20) family
CK938_28310	COG0662	Cupin 2, conserved barrel domain protein
CK938_28345	COG0071	Belongs to the small heat shock protein (HSP20) family
CK938_28370	COG0346	lactoylglutathione lyase activity