locus-tag	class	description
WR51_00010	COG0592	DNA-directed DNA polymerase activity
WR51_00015	COG2501	S4 domain
WR51_00025	COG0187	DNA topoisomerase II activity
WR51_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR51_00065	COG0516	GMP reductase activity
WR51_00065	COG0517	IMP dehydrogenase activity
WR51_00070	COG1686	Belongs to the peptidase S11 family
WR51_00100	COG1428	Deoxynucleoside kinase
WR51_00105	COG1428	Deoxynucleoside kinase
WR51_00110	COG1335	isochorismatase
WR51_00120	COG0590	tRNA wobble adenosine to inosine editing
WR51_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WR51_00180	COG1982	Orn Lys Arg decarboxylase major
WR51_00190	COG0470	DNA polymerase III
WR51_00195	COG1774	PSP1 C-terminal conserved region
WR51_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WR51_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WR51_00220	COG2002	toxin-antitoxin pair type II binding
WR51_00230	COG0084	hydrolase, TatD family'
WR51_00250	COG4466	Protein conserved in bacteria
WR51_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WR51_00270	COG0251	oxidation-reduction process
WR51_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WR51_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WR51_00305	COG2002	toxin-antitoxin pair type II binding
WR51_00310	COG2244	polysaccharide biosynthetic process
WR51_00315	COG3956	TIGRFAM MazG family protein
WR51_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WR51_00340	COG1098	S1 RNA binding domain
WR51_00355	COG2208	phosphoserine phosphatase activity
WR51_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WR51_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WR51_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
WR51_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WR51_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WR51_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WR51_00420	COG1396	sequence-specific DNA binding
WR51_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR51_00515	COG3880	PFAM UvrB UvrC protein
WR51_00525	COG0542	response to heat
WR51_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WR51_00540	COG4956	integral membrane protein (PIN domain superfamily)
WR51_00560	COG1045	serine acetyltransferase
WR51_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR51_00580	COG3688	RNA-binding protein containing a PIN domain
WR51_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WR51_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR51_00600	COG0250	Participates in transcription elongation, termination and antitermination
WR51_00625	COG2813	Specifically methylates the guanine in position
WR51_00640	COG1358	cellular component organization or biogenesis
WR51_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WR51_00770	COG0201	protein transport
WR51_00780	COG0024	Methionine aminopeptidase
WR51_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WR51_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR51_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_00855	COG0489	protein tyrosine kinase activity
WR51_00865	COG2194	sulfuric ester hydrolase activity
WR51_00870	COG0726	polysaccharide deacetylase
WR51_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
WR51_00955	COG4856	YbbR-like protein
WR51_00995	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_01000	COG2011	ABC-type metal ion transport system permease component
WR51_01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WR51_01010	COG1464	Belongs to the NlpA lipoprotein family
WR51_01015	COG0604	alcohol dehydrogenase
WR51_01025	COG0277	FAD linked oxidase domain protein
WR51_01030	COG2271	Major facilitator Superfamily
WR51_01040	COG2814	Major facilitator Superfamily
WR51_01060	COG0601	transmembrane transport
WR51_01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_01070	COG0444	Belongs to the ABC transporter superfamily
WR51_01075	COG4608	Belongs to the ABC transporter superfamily
WR51_01080	COG4166	transmembrane transport
WR51_01095	COG4166	transmembrane transport
WR51_01100	COG4166	transmembrane transport
WR51_01105	COG0656	L-ascorbic acid biosynthetic process
WR51_01130	COG4149	molybdate abc transporter
WR51_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
WR51_01140	COG1910	domain protein
WR51_01160	COG0697	spore germination
WR51_01175	COG0204	Acyl-transferase
WR51_01185	COG1609	Transcriptional regulator
WR51_01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_01215	COG5298	Protein conserved in bacteria
WR51_01240	COG0488	(ABC) transporter
WR51_01250	COG0747	negative chemotaxis
WR51_01255	COG0601	transmembrane transport
WR51_01265	COG0444	Belongs to the ABC transporter superfamily
WR51_01270	COG4608	Belongs to the ABC transporter superfamily
WR51_01275	COG0561	phosphatase activity
WR51_01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
WR51_01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR51_01320	COG0531	amino acid
WR51_01325	COG2814	Major facilitator Superfamily
WR51_01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR51_01345	COG4294	response to UV
WR51_01350	COG0705	Rhomboid family
WR51_01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WR51_01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR51_01370	COG0864	Transcriptional regulator
WR51_01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
WR51_01380	COG2183	response to ionizing radiation
WR51_01480	COG0802	atpase or kinase
WR51_01485	COG1214	PFAM Peptidase M22, glycoprotease
WR51_01490	COG0456	acetyltransferase
WR51_01500	COG0488	(ABC) transporter
WR51_01515	COG1266	CAAX protease self-immunity
WR51_01545	COG2252	PERMEase
WR51_01555	COG5002	protein histidine kinase activity
WR51_01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR51_01600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_01605	COG0506	proline dehydrogenase activity
WR51_01650	COG2205	protein histidine kinase activity
WR51_01655	COG0745	RESPONSE REGULATOR receiver
WR51_01675	COG0697	spore germination
WR51_01705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WR51_01710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WR51_01715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WR51_01725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WR51_01740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WR51_01750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WR51_01760	COG0151	Belongs to the GarS family
WR51_01770	COG0583	DNA-binding transcription factor activity
WR51_01795	COG0210	DNA helicase
WR51_01805	COG4851	CamS sex pheromone cAM373 precursor
WR51_01820	COG1335	isochorismatase
WR51_01835	COG2011	ABC-type metal ion transport system permease component
WR51_01840	COG1464	Belongs to the NlpA lipoprotein family
WR51_01855	COG0003	Pfam Anion-transporting ATPase
WR51_01860	COG1846	Transcriptional regulator
WR51_01865	COG4682	membrane
WR51_01885	COG1597	lipid kinase activity
WR51_01895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WR51_01905	COG1012	belongs to the aldehyde dehydrogenase family
WR51_01910	COG2076	Multidrug Resistance protein
WR51_01915	COG2309	aminopeptidase activity
WR51_01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR51_01945	COG4807	Protein conserved in bacteria
WR51_01975	COG1473	amidohydrolase
WR51_01995	COG0450	alkyl hydroperoxide reductase
WR51_02000	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
WR51_02010	COG0235	Class ii aldolase
WR51_02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_02025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_02050	COG0166	Belongs to the GPI family
WR51_02075	COG5002	protein histidine kinase activity
WR51_02095	COG3541	Predicted nucleotidyltransferase
WR51_02100	COG2814	Major facilitator Superfamily
WR51_02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_02105	COG0723	plastoquinol--plastocyanin reductase activity
WR51_02115	COG0765	amino acid transport
WR51_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_02130	COG0840	transmembrane signaling receptor activity
WR51_02155	COG0549	Belongs to the carbamate kinase family
WR51_02160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_02170	COG0277	FAD linked oxidase domain protein
WR51_02175	COG0366	Alpha amylase catalytic
WR51_02180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_02180	COG2190	(PTS) system
WR51_02180	COG1263	PTS System
WR51_02210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WR51_02230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_02235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_02240	COG1116	anion transmembrane transporter activity
WR51_02245	COG0488	(ABC) transporter
WR51_02290	COG2270	Major facilitator Superfamily
WR51_02320	COG2310	stress, protein
WR51_02325	COG2310	stress, protein
WR51_02330	COG2310	stress, protein
WR51_02335	COG0861	Integral membrane protein TerC family
WR51_02345	COG3853	Toxic anion resistance protein (TelA)
WR51_02360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WR51_02370	COG1295	ribonuclease BN
WR51_02375	COG2217	Heavy metal translocating P-type atpase
WR51_02380	COG0697	spore germination
WR51_02400	COG0586	Pfam SNARE associated Golgi protein
WR51_02415	COG3871	stress protein (general stress protein 26)
WR51_02420	COG0387	Pfam Sodium calcium exchanger
WR51_02430	COG0535	radical SAM domain protein
WR51_02450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR51_02455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WR51_02470	COG3829	transcription factor binding
WR51_02480	COG0833	amino acid
WR51_02485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_02515	COG1263	PTS System
WR51_02520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_02535	COG1216	Glycosyl transferase, family 2
WR51_02545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WR51_02545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_02550	COG0463	Glycosyl transferase, family 2
WR51_02565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WR51_02585	COG1228	amidohydrolase
WR51_02590	COG1090	epimerase
WR51_02620	COG1988	membrane-bound metal-dependent
WR51_02625	COG1194	a g-specific adenine glycosylase
WR51_02650	COG1132	(ABC) transporter
WR51_02655	COG4129	membrane
WR51_02660	COG0067	glutamate synthase
WR51_02660	COG0069	glutamate synthase activity
WR51_02660	COG0070	glutamate synthase
WR51_02670	COG4555	ABC transporter
WR51_02690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WR51_02695	COG0735	belongs to the Fur family
WR51_02875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WR51_02900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WR51_02905	COG5001	Diguanylate cyclase
WR51_02905	COG1716	ATPase activity
WR51_02915	COG2766	serine protein kinase
WR51_02960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_02960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_02960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_02960	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_02960	COG3321	synthase
WR51_02990	COG2801	Transposase and inactivated derivatives
WR51_03015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_03025	COG1585	Membrane protein implicated in regulation of membrane protease activity
WR51_03030	COG2268	Band 7 protein
WR51_03040	COG3290	protein histidine kinase activity
WR51_03045	COG4565	transcriptional regulatory protein
WR51_03050	COG2851	Citrate transporter
WR51_03075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR51_03080	COG3842	ATPase activity
WR51_03085	COG1175	transmembrane transport
WR51_03090	COG0395	ABC-type sugar transport system, permease component
WR51_03100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WR51_03105	COG0745	RESPONSE REGULATOR receiver
WR51_03110	COG5002	protein histidine kinase activity
WR51_03120	COG4990	cell redox homeostasis
WR51_03130	COG3290	protein histidine kinase activity
WR51_03135	COG4565	transcriptional regulatory protein
WR51_03140	COG3493	citrate carrier protein
WR51_03145	COG0281	malic enzyme
WR51_03155	COG0697	spore germination
WR51_03160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_03170	COG5002	protein histidine kinase activity
WR51_03175	COG0745	RESPONSE REGULATOR receiver
WR51_03185	COG0454	-acetyltransferase
WR51_03185	COG0456	acetyltransferase
WR51_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR51_03195	COG3383	formate dehydrogenase (NAD+) activity
WR51_03200	COG2427	Protein of unknown function (DUF1641)
WR51_03215	COG0531	amino acid
WR51_03225	COG0640	Transcriptional regulator
WR51_03230	COG2217	Heavy metal translocating P-type atpase
WR51_03235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WR51_03245	COG3227	Zinc metalloprotease (Elastase)
WR51_03265	COG2720	vancomycin resistance protein
WR51_03270	COG1316	TRANSCRIPTIONal
WR51_03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_03280	COG0346	lactoylglutathione lyase activity
WR51_03285	COG1253	flavin adenine dinucleotide binding
WR51_03290	COG1027	Aspartate ammonia-lyase
WR51_03295	COG1620	l-lactate permease
WR51_03310	COG3104	oligopeptide transport
WR51_03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_03340	COG0156	8-amino-7-oxononanoate synthase activity
WR51_03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_03350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WR51_03360	COG4548	von Willebrand factor, type A
WR51_03365	COG0714	Associated with various cellular activities
WR51_03385	COG0531	amino acid
WR51_03390	COG2188	Transcriptional regulator
WR51_03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_03395	COG1263	PTS System
WR51_03400	COG0366	Alpha amylase catalytic
WR51_03415	COG0697	spore germination
WR51_03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_03430	COG1115	amino acid carrier protein
WR51_03435	COG1126	abc transporter atp-binding protein
WR51_03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_03445	COG0765	amino acid transport
WR51_03450	COG0765	amino acid transport
WR51_03455	COG0833	amino acid
WR51_03470	COG1595	DNA-templated transcription, initiation
WR51_03480	COG2378	regulation of single-species biofilm formation
WR51_03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WR51_03490	COG5002	protein histidine kinase activity
WR51_03515	COG0659	secondary active sulfate transmembrane transporter activity
WR51_03530	COG0747	negative chemotaxis
WR51_03540	COG0601	transmembrane transport
WR51_03545	COG4608	Belongs to the ABC transporter superfamily
WR51_03555	COG2271	Major facilitator Superfamily
WR51_03560	COG1846	Transcriptional regulator
WR51_03565	COG0477	Major facilitator Superfamily
WR51_03570	COG1609	Transcriptional regulator
WR51_03575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WR51_03590	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_03595	COG1879	ABC-type sugar transport system periplasmic component
WR51_03600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WR51_03620	COG1063	alcohol dehydrogenase
WR51_03670	COG0840	transmembrane signaling receptor activity
WR51_03675	COG3584	3D domain protein
WR51_03675	COG3583	domain protein
WR51_03680	COG1476	TRANSCRIPTIONal
WR51_03700	COG3104	oligopeptide transport
WR51_03705	COG1114	Component of the transport system for branched-chain amino acids
WR51_03720	COG1113	amino acid transport
WR51_03725	COG2252	PERMEase
WR51_03740	COG2153	protein acetylation
WR51_03750	COG0569	domain protein
WR51_03750	COG0475	glutathione-regulated potassium exporter activity
WR51_03760	COG1845	cytochrome c oxidase, subunit III
WR51_03765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WR51_03775	COG0833	amino acid
WR51_03780	COG4990	cell redox homeostasis
WR51_03795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_03800	COG0697	spore germination
WR51_03805	COG0531	amino acid
WR51_03820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_03825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_03830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_03830	COG1918	ferrous iron import across plasma membrane
WR51_03835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR51_03845	COG0581	inorganic phosphate transmembrane transporter activity
WR51_03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR51_03975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
WR51_04000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR51_04005	COG1116	anion transmembrane transporter activity
WR51_04010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_04015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_04020	COG0352	thiamine-phosphate diphosphorylase activity
WR51_04025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_04030	COG2104	thiamine diphosphate biosynthetic process
WR51_04040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_04045	COG0351	phosphomethylpyrimidine kinase
WR51_04085	COG2205	protein histidine kinase activity
WR51_04090	COG2814	Major facilitator Superfamily
WR51_04095	COG1846	Transcriptional regulator
WR51_04110	COG2801	Transposase and inactivated derivatives
WR51_04120	COG2252	PERMEase
WR51_04125	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_04185	COG0778	Nitroreductase
WR51_04190	COG2719	SpoVR family
WR51_04200	COG1414	Transcriptional regulator
WR51_04215	COG0446	pyridine nucleotide-disulphide oxidoreductase
WR51_04220	COG1937	Protein conserved in bacteria
WR51_04225	COG0425	Belongs to the sulfur carrier protein TusA family
WR51_04225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_04230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_04235	COG0425	Belongs to the sulfur carrier protein TusA family
WR51_04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_04250	COG2210	Belongs to the sulfur carrier protein TusA family
WR51_04255	COG0730	response to heat
WR51_04265	COG1316	TRANSCRIPTIONal
WR51_04270	COG0604	alcohol dehydrogenase
WR51_04275	COG1283	sodium-dependent phosphate transmembrane transporter activity
WR51_04290	COG3711	transcriptional antiterminator
WR51_04290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_04295	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_04300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_04320	COG3584	3D domain protein
WR51_04320	COG1388	LysM domain
WR51_04325	COG0577	efflux transmembrane transporter activity
WR51_04330	COG1136	(ABC) transporter
WR51_04340	COG5522	Integral membrane protein (intg_mem_TP0381)
WR51_04355	COG1114	Component of the transport system for branched-chain amino acids
WR51_04360	COG3546	catalase activity
WR51_04395	COG0586	Pfam SNARE associated Golgi protein
WR51_04430	COG0531	amino acid
WR51_04435	COG0475	glutathione-regulated potassium exporter activity
WR51_04445	COG1737	Transcriptional regulator
WR51_04455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_04455	COG1263	PTS System
WR51_04465	COG2259	Doxx family
WR51_04485	COG1522	sequence-specific DNA binding
WR51_04490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WR51_04490	COG0165	Argininosuccinate lyase
WR51_04495	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_04505	COG2076	Multidrug Resistance protein
WR51_04515	COG1309	transcriptional regulator
WR51_04520	COG2814	Major facilitator Superfamily
WR51_04525	COG1733	regulation of RNA biosynthetic process
WR51_04545	COG0693	protein deglycase activity
WR51_04560	COG0531	amino acid
WR51_04575	COG1012	belongs to the aldehyde dehydrogenase family
WR51_04585	COG1132	(ABC) transporter
WR51_04590	COG1132	(ABC) transporter
WR51_04595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_04600	COG0765	amino acid transport
WR51_04605	COG1126	abc transporter atp-binding protein
WR51_04620	COG0189	ligase activity
WR51_04640	COG4585	Histidine kinase
WR51_04645	COG2197	response regulator
WR51_04665	COG0028	Belongs to the TPP enzyme family
WR51_04670	COG3527	Alpha-acetolactate decarboxylase
WR51_04680	COG0561	phosphatase activity
WR51_04690	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_04690	COG3409	Peptidoglycan-binding domain 1 protein
WR51_04695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR51_04700	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_04715	COG0659	secondary active sulfate transmembrane transporter activity
WR51_04720	COG2244	polysaccharide biosynthetic process
WR51_04740	COG1024	Enoyl-CoA hydratase
WR51_04760	COG1363	Peptidase, m42
WR51_04800	COG0601	transmembrane transport
WR51_04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_04810	COG0444	Belongs to the ABC transporter superfamily
WR51_04815	COG4608	Belongs to the ABC transporter superfamily
WR51_04855	COG0477	Major facilitator Superfamily
WR51_04860	COG3290	protein histidine kinase activity
WR51_04865	COG4565	transcriptional regulatory protein
WR51_04870	COG3181	Tripartite tricarboxylate transporter family receptor
WR51_04935	COG0305	Participates in initiation and elongation during chromosome replication
WR51_04975	COG0477	Major facilitator Superfamily
WR51_04985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_05000	COG5504	Zn-dependent protease
WR51_05005	COG0789	Transcriptional regulator
WR51_05040	COG1329	Transcriptional regulator
WR51_05055	COG1278	Cold shock
WR51_05070	COG1131	(ABC) transporter
WR51_05100	COG2373	Large extracellular alpha-helical protein
WR51_05130	COG1073	alpha beta
WR51_05180	COG1183	phosphatidylcholine synthase activity
WR51_05195	COG2814	Major facilitator Superfamily
WR51_05200	COG0640	Transcriptional regulator
WR51_05210	COG2376	Dihydroxyacetone kinase
WR51_05220	COG2376	Dihydroxyacetone kinase
WR51_05255	COG0457	Tetratricopeptide repeat
WR51_05260	COG2373	Large extracellular alpha-helical protein
WR51_05300	COG3237	CsbD-like
WR51_05325	COG1191	sigma factor activity
WR51_05335	COG2208	phosphoserine phosphatase activity
WR51_05340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR51_05385	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
WR51_05405	COG0420	3'-5' exonuclease activity
WR51_05410	COG4717	serine-type aminopeptidase activity
WR51_05430	COG1280	lysine exporter protein (LysE YggA)
WR51_05435	COG0346	lactoylglutathione lyase activity
WR51_05440	COG0346	lactoylglutathione lyase activity
WR51_05450	COG0457	Tetratricopeptide repeat
WR51_05460	COG2267	carboxylic ester hydrolase activity
WR51_05475	COG2140	Oxalate decarboxylase
WR51_05480	COG3620	sequence-specific DNA binding
WR51_05490	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR51_05495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WR51_05505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WR51_05515	COG1595	DNA-templated transcription, initiation
WR51_05525	COG0772	Belongs to the SEDS family
WR51_05530	COG3973	AAA domain
WR51_05560	COG4980	gas vesicle protein
WR51_05565	COG0537	adenosine 5'-monophosphoramidase activity
WR51_05570	COG1131	(ABC) transporter
WR51_05575	COG4473	ABC transporter
WR51_05625	COG1309	transcriptional regulator
WR51_05635	COG3402	PFAM membrane-flanked domain
WR51_05640	COG3428	Bacterial PH domain
WR51_05685	COG0697	spore germination
WR51_05690	COG3402	PFAM membrane-flanked domain
WR51_05695	COG3428	Bacterial PH domain
WR51_05700	COG2329	Antibiotic biosynthesis monooxygenase
WR51_05705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_05755	COG1309	transcriptional regulator
WR51_05760	COG1511	domain protein
WR51_05780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_05785	COG1609	Transcriptional regulator
WR51_05795	COG1234	tRNA 3'-trailer cleavage
WR51_05800	COG0095	Lipoate-protein ligase
WR51_05810	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_05820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WR51_05830	COG4208	sulfate ABC transporter
WR51_05850	COG1408	metallophosphoesterase
WR51_05855	COG1078	dGTPase activity
WR51_05865	COG1595	DNA-templated transcription, initiation
WR51_05870	COG3708	Transcriptional regulator
WR51_05870	COG2207	Transcriptional regulator
WR51_05880	COG2205	protein histidine kinase activity
WR51_05885	COG0745	RESPONSE REGULATOR receiver
WR51_05905	COG0501	Belongs to the peptidase M48B family
WR51_05910	COG0840	transmembrane signaling receptor activity
WR51_05915	COG3693	PFAM glycoside hydrolase, family 10
WR51_05925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WR51_05930	COG2224	Isocitrate lyase
WR51_05945	COG1278	Cold shock
WR51_05965	COG0398	Pfam SNARE associated Golgi protein
WR51_05985	COG0202	RNA polymerase activity
WR51_06025	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR51_06050	COG0367	asparagine synthase
WR51_06060	COG0753	catalase activity
WR51_06065	COG0004	ammonium transporteR
WR51_06085	COG2996	Protein conserved in bacteria
WR51_06100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_06115	COG0561	phosphatase activity
WR51_06140	COG2267	carboxylic ester hydrolase activity
WR51_06155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_06160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WR51_06165	COG5504	Zn-dependent protease
WR51_06175	COG0180	Tryptophanyl-tRNA synthetase
WR51_06185	COG4166	transmembrane transport
WR51_06190	COG0601	transmembrane transport
WR51_06195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_06200	COG0444	Belongs to the ABC transporter superfamily
WR51_06205	COG4608	Belongs to the ABC transporter superfamily
WR51_06210	COG0534	Mate efflux family protein
WR51_06215	COG4166	transmembrane transport
WR51_06230	COG1393	Belongs to the ArsC family
WR51_06235	COG0861	Integral membrane protein TerC family
WR51_06245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_06255	COG1164	Oligoendopeptidase f
WR51_06270	COG2346	COG2346, Truncated hemoglobins
WR51_06275	COG4116	CYTH
WR51_06285	COG2357	RelA SpoT domain protein
WR51_06295	COG0564	pseudouridine synthase activity
WR51_06310	COG0772	Belongs to the SEDS family
WR51_06315	COG1216	Glycosyl transferase, family 2
WR51_06335	COG0463	Glycosyl transferase, family 2
WR51_06335	COG0457	Tetratricopeptide repeat
WR51_06355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WR51_06370	COG1091	dTDP-4-dehydrorhamnose reductase activity
WR51_06415	COG2153	protein acetylation
WR51_06425	COG2382	esterase
WR51_06455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_06470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WR51_06470	COG0512	Glutamine amidotransferase of anthranilate synthase
WR51_06515	COG1620	l-lactate permease
WR51_06525	COG5634	Uncharacterized conserved protein (DUF2278)
WR51_06575	COG2226	methyltransferase
WR51_06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_06605	COG1476	TRANSCRIPTIONal
WR51_06670	COG2226	methyltransferase
WR51_06680	COG1686	Belongs to the peptidase S11 family
WR51_06685	COG0681	Belongs to the peptidase S26 family
WR51_06720	COG1012	belongs to the aldehyde dehydrogenase family
WR51_06730	COG1176	ABC-type spermidine putrescine transport system, permease component I
WR51_06735	COG1177	transmembrane transport
WR51_06740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WR51_06750	COG2409	Drug exporters of the RND superfamily
WR51_06760	COG0564	pseudouridine synthase activity
WR51_06770	COG2340	Cysteine-rich secretory protein family
WR51_06775	COG0247	lactate metabolic process
WR51_06780	COG0277	FAD linked oxidase domain protein
WR51_06785	COG3835	regulator
WR51_06795	COG0745	RESPONSE REGULATOR receiver
WR51_06800	COG5002	protein histidine kinase activity
WR51_06805	COG2186	Transcriptional regulator
WR51_06825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WR51_06835	COG2116	formate transmembrane transporter activity
WR51_06840	COG0861	Integral membrane protein TerC family
WR51_06845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_06855	COG2030	dehydratase
WR51_06875	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_06880	COG3243	poly(R)-hydroxyalkanoic acid synthase
WR51_06890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_06905	COG1840	ABC-type Fe3 transport system, periplasmic component
WR51_06910	COG3842	ATPase activity
WR51_06935	COG1349	DNA-binding transcription factor activity
WR51_06950	COG0235	Class ii aldolase
WR51_06960	COG2861	carbohydrate metabolic process
WR51_06970	COG3852	Histidine kinase
WR51_06975	COG1846	Transcriptional regulator
WR51_06985	COG2318	DinB family
WR51_06995	COG5002	protein histidine kinase activity
WR51_07005	COG0720	synthase
WR51_07020	COG4873	Protein conserved in bacteria
WR51_07060	COG1780	Probably involved in ribonucleotide reductase function
WR51_07065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR51_07070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR51_07075	COG1725	Transcriptional regulator
WR51_07080	COG1131	(ABC) transporter
WR51_07090	COG1131	(ABC) transporter
WR51_07110	COG1522	sequence-specific DNA binding
WR51_07120	COG1335	isochorismatase
WR51_07130	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_07135	COG2070	2-Nitropropane dioxygenase
WR51_07140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR51_07150	COG1696	Membrane protein involved in D-alanine export
WR51_07175	COG0716	FMN binding
WR51_07230	COG1846	Transcriptional regulator
WR51_07240	COG1301	dicarboxylic acid transport
WR51_07245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_07250	COG4709	membrane
WR51_07255	COG3874	Sporulation protein YtfJ
WR51_07285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_07290	COG0028	Belongs to the TPP enzyme family
WR51_07295	COG0440	acetolactate synthase activity
WR51_07370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR51_07385	COG1183	phosphatidylcholine synthase activity
WR51_07390	COG1368	sulfuric ester hydrolase activity
WR51_07400	COG0019	diaminopimelate decarboxylase activity
WR51_07420	COG0529	Catalyzes the synthesis of activated sulfate
WR51_07425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR51_07445	COG1648	precorrin-2 dehydrogenase activity
WR51_07455	COG0733	neurotransmitter:sodium symporter activity
WR51_07475	COG1757	Na H antiporter
WR51_07490	COG4758	membrane
WR51_07495	COG4585	Histidine kinase
WR51_07500	COG2197	response regulator
WR51_07510	COG1114	Component of the transport system for branched-chain amino acids
WR51_07520	COG2226	methyltransferase
WR51_07565	COG0730	response to heat
WR51_07570	COG0306	phosphate transporter
WR51_07575	COG1392	Phosphate transport regulator
WR51_07580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_07595	COG3852	Histidine kinase
WR51_07600	COG1801	Protein of unknown function DUF72
WR51_07610	COG0582	viral genome integration into host DNA
WR51_07615	COG5002	protein histidine kinase activity
WR51_07630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WR51_07630	COG0392	lysyltransferase activity
WR51_07645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR51_07650	COG1686	Belongs to the peptidase S11 family
WR51_07655	COG2715	membrane protein required for spore maturation
WR51_07660	COG0700	Nucleoside recognition
WR51_07665	COG1187	pseudouridine synthase activity
WR51_07675	COG1333	cytochrome c biogenesis protein
WR51_07680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR51_07685	COG0745	RESPONSE REGULATOR receiver
WR51_07690	COG5002	protein histidine kinase activity
WR51_07695	COG2096	Adenosyltransferase
WR51_07710	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
WR51_07715	COG1141	Ferredoxin
WR51_07725	COG0514	ATP-dependent DNA helicase (RecQ)
WR51_07730	COG1266	CAAX protease self-immunity
WR51_07740	COG1408	metallophosphoesterase
WR51_07745	COG0789	Transcriptional regulator
WR51_07755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WR51_07775	COG0492	ferredoxin-NADP+ reductase activity
WR51_07780	COG0252	asparaginase activity
WR51_07850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_07865	COG0142	geranyltranstransferase activity
WR51_07875	COG0142	geranyltranstransferase activity
WR51_07900	COG0457	Tetratricopeptide repeat
WR51_07920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR51_07925	COG2010	Cytochrome c
WR51_07925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR51_07930	COG4347	Protein of unknown function (DUF1405)
WR51_07945	COG2738	Putative neutral zinc metallopeptidase
WR51_07955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_07960	COG1694	Mazg nucleotide pyrophosphohydrolase
WR51_07980	COG0438	transferase activity, transferring glycosyl groups
WR51_08020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WR51_08020	COG1199	ATP-dependent helicase activity
WR51_08040	COG3935	DnaD domain protein
WR51_08045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WR51_08055	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR51_08055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_08105	COG0116	Belongs to the methyltransferase superfamily
WR51_08115	COG1199	ATP-dependent helicase activity
WR51_08120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WR51_08130	COG0024	Methionine aminopeptidase
WR51_08140	COG2233	PERMEase
WR51_08150	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_08160	COG0456	acetyltransferase
WR51_08200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_08215	COG3944	biosynthesis protein
WR51_08225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR51_08240	COG1215	transferase activity, transferring glycosyl groups
WR51_08245	COG0438	transferase activity, transferring glycosyl groups
WR51_08280	COG0328	RNA-DNA hybrid ribonuclease activity
WR51_08315	COG3403	YqcI/YcgG family
WR51_08320	COG1280	lysine exporter protein (LysE YggA)
WR51_08340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_08345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_08355	COG0475	glutathione-regulated potassium exporter activity
WR51_08360	COG0789	Transcriptional regulator
WR51_08360	COG4978	Transcriptional regulator
WR51_08370	COG2323	membrane
WR51_08375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WR51_08385	COG2801	Transposase and inactivated derivatives
WR51_08445	COG1923	regulation of RNA biosynthetic process
WR51_08455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR51_08460	COG1360	Flagellar Motor Protein
WR51_08465	COG2201	protein-glutamate methylesterase activity
WR51_08470	COG2198	Histidine kinase
WR51_08470	COG0643	Histidine kinase
WR51_08475	COG1776	CheC inhibitor of MCP methylation
WR51_08475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_08490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR51_08510	COG1256	bacterial-type flagellum assembly
WR51_08515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR51_08535	COG1815	bacterial-type flagellum-dependent cell motility
WR51_08540	COG1558	bacterial-type flagellum-dependent cell motility
WR51_08545	COG1677	Flagellar hook-basal body complex protein FliE
WR51_08550	COG1766	The M ring may be actively involved in energy transduction
WR51_08555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_08565	COG1157	protein secretion by the type III secretion system
WR51_08585	COG1749	Flagellar hook protein flgE
WR51_08600	COG0835	chemotaxis
WR51_08600	COG0784	Response regulator, receiver
WR51_08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR51_08620	COG0741	lytic transglycosylase activity
WR51_08630	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_08635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_08635	COG1776	CheC inhibitor of MCP methylation
WR51_08645	COG1338	Plays a role in the flagellum-specific transport system
WR51_08650	COG1987	bacterial-type flagellum assembly
WR51_08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR51_08665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR51_08670	COG1419	protein localization to endoplasmic reticulum
WR51_08675	COG4786	Flagellar basal body rod
WR51_08685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR51_08720	COG2329	Antibiotic biosynthesis monooxygenase
WR51_08750	COG3842	ATPase activity
WR51_08760	COG1177	transmembrane transport
WR51_08790	COG0406	alpha-ribazole phosphatase activity
WR51_08820	COG0367	asparagine synthase
WR51_08850	COG1802	Transcriptional regulator
WR51_08855	COG0697	spore germination
WR51_08865	COG0523	cobalamin synthesis protein
WR51_08870	COG0701	Predicted permease
WR51_08885	COG1757	Na H antiporter
WR51_08890	COG0789	Transcriptional regulator
WR51_08925	COG0534	Mate efflux family protein
WR51_08930	COG3340	Belongs to the peptidase S51 family
WR51_08950	COG0785	Cytochrome C biogenesis protein
WR51_08955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_08965	COG0457	Tetratricopeptide repeat
WR51_08985	COG2733	membrane
WR51_09020	COG1131	(ABC) transporter
WR51_09035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_09040	COG0528	UMP kinase activity
WR51_09050	COG1027	Aspartate ammonia-lyase
WR51_09055	COG0281	malic enzyme
WR51_09060	COG4191	Histidine kinase
WR51_09065	COG0784	Response regulator, receiver
WR51_09070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_09130	COG2814	Major facilitator Superfamily
WR51_09150	COG1695	Transcriptional regulator
WR51_09160	COG0477	Major facilitator Superfamily
WR51_09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR51_09180	COG2223	nitrite transmembrane transporter activity
WR51_09185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_09205	COG0733	neurotransmitter:sodium symporter activity
WR51_09215	COG5566	PFAM Mor transcription activator
WR51_09220	COG2323	membrane
WR51_09240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_09250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_09255	COG0028	Belongs to the TPP enzyme family
WR51_09275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WR51_09300	COG2814	Major facilitator Superfamily
WR51_09305	COG3384	dioxygenase
WR51_09315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR51_09320	COG3279	Response regulator of the LytR AlgR family
WR51_09325	COG0427	acetyl-CoA hydrolase
WR51_09360	COG4166	transmembrane transport
WR51_09390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_09410	COG1914	H( )-stimulated, divalent metal cation uptake system
WR51_09425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR51_09435	COG0531	amino acid
WR51_09445	COG0083	homoserine kinase activity
WR51_09460	COG2309	aminopeptidase activity
WR51_09480	COG0456	acetyltransferase
WR51_09495	COG1309	transcriptional regulator
WR51_09500	COG2390	Transcriptional regulator
WR51_09510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_09515	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WR51_09525	COG4846	Membrane protein involved in cytochrome C biogenesis
WR51_09545	COG0583	DNA-binding transcription factor activity
WR51_09560	COG0006	proline dipeptidase activity
WR51_09570	COG2132	Multicopper oxidase
WR51_09600	COG1114	Component of the transport system for branched-chain amino acids
WR51_09610	COG2372	response to copper ion
WR51_09610	COG1276	copper resistance
WR51_09615	COG4549	nuclear export factor GLE1
WR51_09620	COG0697	spore germination
WR51_09625	COG0583	DNA-binding transcription factor activity
WR51_09630	COG1959	2 iron, 2 sulfur cluster binding
WR51_09635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR51_09640	COG0778	Nitroreductase
WR51_09655	COG0628	permease
WR51_09665	COG1231	oxidoreductase activity
WR51_09670	COG0523	cobalamin synthesis protein
WR51_09680	COG0411	ABC transporter
WR51_09700	COG0583	DNA-binding transcription factor activity
WR51_09710	COG1942	4-Oxalocrotonate Tautomerase
WR51_09730	COG1271	oxidase subunit
WR51_09735	COG1294	oxidase, subunit
WR51_09740	COG4988	ABC transporter
WR51_09745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WR51_09755	COG1216	Glycosyl transferase, family 2
WR51_09795	COG1686	Belongs to the peptidase S11 family
WR51_09810	COG0791	NLP P60 protein
WR51_09810	COG1388	LysM domain
WR51_09820	COG1132	(ABC) transporter
WR51_09825	COG0745	RESPONSE REGULATOR receiver
WR51_09830	COG5002	protein histidine kinase activity
WR51_09840	COG0300	oxidoreductase activity
WR51_09855	COG0726	polysaccharide deacetylase
WR51_09875	COG0460	homoserine dehydrogenase
WR51_09900	COG1316	TRANSCRIPTIONal
WR51_09910	COG0745	RESPONSE REGULATOR receiver
WR51_09915	COG5002	protein histidine kinase activity
WR51_09920	COG0726	polysaccharide deacetylase
WR51_09930	COG1285	pathogenesis
WR51_09935	COG1247	-acetyltransferase
WR51_09945	COG4264	IucA IucC family
WR51_09950	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_09965	COG1082	Xylose isomerase domain protein TIM barrel
WR51_09975	COG2814	Major facilitator Superfamily
WR51_09980	COG1279	arginine transmembrane transporter activity
WR51_09985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_09995	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR51_10030	COG0577	efflux transmembrane transporter activity
WR51_10035	COG2002	toxin-antitoxin pair type II binding
WR51_10040	COG1404	Belongs to the peptidase S8 family
WR51_10045	COG0640	Transcriptional regulator
WR51_10050	COG0667	Aldo Keto reductase
WR51_10080	COG0840	transmembrane signaling receptor activity
WR51_10100	COG3949	Membrane
WR51_10105	COG0783	Belongs to the Dps family
WR51_10120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_10130	COG1231	oxidoreductase activity
WR51_10135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_10140	COG4989	oxidoreductase activity
WR51_10145	COG0523	cobalamin synthesis protein
WR51_10150	COG0456	acetyltransferase
WR51_10155	COG0803	Belongs to the bacterial solute-binding protein 9 family
WR51_10165	COG0702	epimerase
WR51_10175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR51_10185	COG4166	transmembrane transport
WR51_10210	COG5337	Spore coat protein CotH
WR51_10215	COG1051	belongs to the nudix hydrolase family
WR51_10220	COG0586	Pfam SNARE associated Golgi protein
WR51_10225	COG2244	polysaccharide biosynthetic process
WR51_10235	COG0701	Predicted permease
WR51_10240	COG3689	TIGRFAM TIGR03943 family protein
WR51_10245	COG1607	acyl-coa hydrolase
WR51_10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_10265	COG0702	epimerase
WR51_10270	COG2839	Protein conserved in bacteria
WR51_10275	COG1253	flavin adenine dinucleotide binding
WR51_10290	COG1114	Component of the transport system for branched-chain amino acids
WR51_10295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR51_10315	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_10325	COG1876	peptidase activity
WR51_10340	COG2211	Major facilitator Superfamily
WR51_10345	COG2801	Transposase and inactivated derivatives
WR51_10365	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_10375	COG0561	phosphatase activity
WR51_10380	COG1846	Transcriptional regulator
WR51_10385	COG2814	Major facilitator Superfamily
WR51_10395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR51_10415	COG1819	glycosyl
WR51_10420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_10425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_10455	COG0456	acetyltransferase
WR51_10505	COG3874	Sporulation protein YtfJ
WR51_10530	COG2226	methyltransferase
WR51_10550	COG1082	Xylose isomerase domain protein TIM barrel
WR51_10555	COG0346	lactoylglutathione lyase activity
WR51_10565	COG0604	alcohol dehydrogenase
WR51_10570	COG1595	DNA-templated transcription, initiation
WR51_10585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR51_10585	COG0426	domain, Protein
WR51_10595	COG0386	Belongs to the glutathione peroxidase family
WR51_10600	COG1305	Transglutaminase-like
WR51_10605	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
WR51_10610	COG0714	Associated with various cellular activities
WR51_10615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WR51_10620	COG1140	nitrate reductase beta subunit
WR51_10625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WR51_10630	COG2181	nitrate reductase activity
WR51_10635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_10640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR51_10645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_10650	COG0303	'Molybdopterin
WR51_10655	COG0314	molybdopterin synthase activity
WR51_10665	COG2223	nitrite transmembrane transporter activity
WR51_10685	COG1648	precorrin-2 dehydrogenase activity
WR51_10695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WR51_10695	COG1587	Uroporphyrinogen-III synthase
WR51_10700	COG2146	nitrite reductase [NAD(P)H] activity
WR51_10705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR51_10710	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
WR51_10745	COG2359	stage V sporulation protein S
WR51_10765	COG1418	mRNA catabolic process
WR51_10770	COG0488	(ABC) transporter
WR51_10785	COG0629	single-stranded DNA binding
WR51_10800	COG1413	lyase activity
WR51_10815	COG2136	Putative SAM-dependent methyltransferase
WR51_10815	COG2521	methyltransferase
WR51_10820	COG0018	arginyl-trna synthetase
WR51_10860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR51_10865	COG0017	Asparaginyl-tRNA synthetase
WR51_10885	COG1674	ftsk spoiiie
WR51_10990	COG0733	neurotransmitter:sodium symporter activity
WR51_11015	COG2610	gluconate transmembrane transporter activity
WR51_11025	COG1794	racemase activity, acting on amino acids and derivatives
WR51_11035	COG0456	acetyltransferase
WR51_11045	COG3655	Transcriptional regulator
WR51_11050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WR51_11060	COG1131	(ABC) transporter
WR51_11065	COG4473	ABC transporter
WR51_11075	COG0546	phosphoglycolate phosphatase activity
WR51_11090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_11105	COG0768	penicillin binding
WR51_11115	COG0204	Acyl-transferase
WR51_11120	COG1272	protein, Hemolysin III
WR51_11130	COG0805	protein transport
WR51_11140	COG1307	EDD domain protein, DegV family
WR51_11150	COG1999	signal sequence binding
WR51_11155	COG0071	Belongs to the small heat shock protein (HSP20) family
WR51_11160	COG0367	asparagine synthase
WR51_11175	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_11185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_11205	COG1335	isochorismatase
WR51_11215	COG0668	transmembrane transport
WR51_11220	COG4585	Histidine kinase
WR51_11220	COG2203	Gaf domain
WR51_11225	COG2197	response regulator
WR51_11230	COG1737	Transcriptional regulator
WR51_11235	COG0384	phenazine biosynthesis protein PhzF
WR51_11240	COG1064	alcohol dehydrogenase
WR51_11265	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR51_11300	COG1125	glycine betaine transport
WR51_11300	COG0517	IMP dehydrogenase activity
WR51_11305	COG1174	glycine betaine transport
WR51_11340	COG1253	flavin adenine dinucleotide binding
WR51_11345	COG1012	belongs to the aldehyde dehydrogenase family
WR51_11350	COG5506	Protein of unknown function (DUF1694)
WR51_11365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_11370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WR51_11375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WR51_11380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_11385	COG0456	acetyltransferase
WR51_11390	COG3829	transcription factor binding
WR51_11395	COG1509	lysine 2,3-aminomutase activity
WR51_11430	COG3064	Membrane
WR51_11430	COG0515	serine threonine protein kinase
WR51_11430	COG4991	sh3 domain protein
WR51_11440	COG0671	phosphoesterase, PA-phosphatase related
WR51_11445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR51_11450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_11550	COG0300	oxidoreductase activity
WR51_11570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_11570	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR51_11580	COG2814	Major facilitator Superfamily
WR51_11585	COG4841	protein insertion into membrane
WR51_11590	COG0372	Belongs to the citrate synthase family
WR51_11595	COG2079	MmgE PrpD family protein
WR51_11600	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WR51_11605	COG1960	acyl-CoA dehydrogenase activity
WR51_11610	COG2084	Dehydrogenase
WR51_11620	COG1280	lysine exporter protein (LysE YggA)
WR51_11625	COG1024	Enoyl-CoA hydratase
WR51_11640	COG0420	3'-5' exonuclease activity
WR51_11645	COG0419	ATPase involved in DNA repair
WR51_11670	COG2223	nitrite transmembrane transporter activity
WR51_11675	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_11680	COG1169	isochorismate synthase
WR51_11685	COG1021	2,3-dihydroxybenzoate-AMP ligase
WR51_11690	COG3433	isochorismatase activity
WR51_11690	COG1535	isochorismatase
WR51_11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_11700	COG3251	PFAM MbtH domain protein
WR51_11705	COG2814	Major facilitator Superfamily
WR51_11720	COG0776	regulation of translation
WR51_11730	COG2318	DinB family
WR51_11740	COG1115	amino acid carrier protein
WR51_11760	COG1187	pseudouridine synthase activity
WR51_11765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR51_11770	COG1136	(ABC) transporter
WR51_11785	COG0028	Belongs to the TPP enzyme family
WR51_11820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_11835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_11860	COG2801	Transposase and inactivated derivatives
WR51_11880	COG1247	-acetyltransferase
WR51_11915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_11945	COG0583	DNA-binding transcription factor activity
WR51_11950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR51_11970	COG0583	DNA-binding transcription factor activity
WR51_11975	COG2258	MOSC domain
WR51_11990	COG1132	(ABC) transporter
WR51_11995	COG1132	(ABC) transporter
WR51_12015	COG0582	viral genome integration into host DNA
WR51_12035	COG1396	sequence-specific DNA binding
WR51_12075	COG2002	toxin-antitoxin pair type II binding
WR51_12115	COG0582	viral genome integration into host DNA
WR51_12155	COG4626	Terminase
WR51_12155	COG1802	Transcriptional regulator
WR51_12165	COG0740	serine-type endopeptidase activity
WR51_12235	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_12265	COG1396	sequence-specific DNA binding
WR51_12300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_12305	COG1595	DNA-templated transcription, initiation
WR51_12330	COG1649	PFAM Uncharacterised BCR, COG1649
WR51_12355	COG2971	BadF BadG BcrA BcrD
WR51_12365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WR51_12375	COG1846	Transcriptional regulator
WR51_12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_12410	COG1309	transcriptional regulator
WR51_12500	COG0500	methyltransferase
WR51_12500	COG3615	Tellurite resistance protein tehB
WR51_12510	COG2226	methyltransferase
WR51_12515	COG3961	Belongs to the TPP enzyme family
WR51_12520	COG1846	Transcriptional regulator
WR51_12570	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR51_12600	COG2002	toxin-antitoxin pair type II binding
WR51_12610	COG0730	response to heat
WR51_12615	COG0110	maltose O-acetyltransferase activity
WR51_12620	COG1686	Belongs to the peptidase S11 family
WR51_12635	COG2814	Major facilitator Superfamily
WR51_12670	COG1115	amino acid carrier protein
WR51_12675	COG2066	Belongs to the glutaminase family
WR51_12680	COG4191	Histidine kinase
WR51_12685	COG0784	Response regulator, receiver
WR51_12690	COG0697	spore germination
WR51_12695	COG0531	amino acid
WR51_12705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_12710	COG0531	amino acid
WR51_12715	COG0322	excinuclease ABC activity
WR51_12725	COG2207	Transcriptional regulator
WR51_12750	COG5002	protein histidine kinase activity
WR51_12795	COG0741	lytic transglycosylase activity
WR51_12800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_12815	COG1396	sequence-specific DNA binding
WR51_12830	COG0726	polysaccharide deacetylase
WR51_12835	COG1309	transcriptional regulator
WR51_12840	COG0367	asparagine synthase
WR51_12845	COG4585	Histidine kinase
WR51_12855	COG1404	Belongs to the peptidase S8 family
WR51_12900	COG0768	penicillin binding
WR51_12905	COG1595	DNA-templated transcription, initiation
WR51_12930	COG1408	metallophosphoesterase
WR51_12940	COG1131	(ABC) transporter
WR51_12950	COG1309	transcriptional regulator
WR51_12965	COG1960	acyl-CoA dehydrogenase activity
WR51_12970	COG0439	Biotin carboxylase
WR51_12975	COG0511	ligase activity, forming carbon-carbon bonds
WR51_12980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WR51_12985	COG1024	Enoyl-CoA hydratase
WR51_12990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WR51_12995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_13025	COG1686	Belongs to the peptidase S11 family
WR51_13050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR51_13065	COG3227	Zinc metalloprotease (Elastase)
WR51_13070	COG2207	Transcriptional regulator
WR51_13100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR51_13110	COG2814	Major facilitator Superfamily
WR51_13115	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_13120	COG1733	regulation of RNA biosynthetic process
WR51_13165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_13175	COG2368	4-hydroxyphenylacetate
WR51_13190	COG1063	alcohol dehydrogenase
WR51_13200	COG2323	membrane
WR51_13205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WR51_13210	COG0693	protein deglycase activity
WR51_13220	COG3386	PFAM SMP-30 Gluconolaconase
WR51_13230	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WR51_13235	COG3773	Cell wall hydrolase
WR51_13245	COG0745	RESPONSE REGULATOR receiver
WR51_13250	COG2205	protein histidine kinase activity
WR51_13275	COG1136	(ABC) transporter
WR51_13280	COG0577	efflux transmembrane transporter activity
WR51_13300	COG0460	homoserine dehydrogenase
WR51_13305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_13315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR51_13340	COG0582	viral genome integration into host DNA
WR51_13365	COG1396	sequence-specific DNA binding
WR51_13395	COG1484	DNA-dependent DNA replication
WR51_13415	COG2002	toxin-antitoxin pair type II binding
WR51_13495	COG0582	viral genome integration into host DNA
WR51_13525	COG5484	DNA packaging
WR51_13540	COG0740	serine-type endopeptidase activity
WR51_13660	COG2124	cytochrome p450
WR51_13695	COG0561	phosphatase activity
WR51_13700	COG5002	protein histidine kinase activity
WR51_13715	COG1819	glycosyl
WR51_13720	COG1794	racemase activity, acting on amino acids and derivatives
WR51_13740	COG2205	protein histidine kinase activity
WR51_13800	COG0604	alcohol dehydrogenase
WR51_13805	COG0671	phosphoesterase, PA-phosphatase related
WR51_13820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_13865	COG2814	Major facilitator Superfamily
WR51_13880	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_13905	COG0697	spore germination
WR51_13950	COG2223	nitrite transmembrane transporter activity
WR51_13965	COG0592	DNA-directed DNA polymerase activity
WR51_14000	COG3878	Protein conserved in bacteria
WR51_14025	COG4667	esterase of the alpha-beta hydrolase superfamily
WR51_14065	COG0322	excinuclease ABC activity
WR51_14105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_14135	COG0745	RESPONSE REGULATOR receiver
WR51_14140	COG5002	protein histidine kinase activity
WR51_14155	COG1522	sequence-specific DNA binding
WR51_14170	COG1136	(ABC) transporter
WR51_14175	COG0577	efflux transmembrane transporter activity
WR51_14190	COG0076	glutamate decarboxylase activity
WR51_14205	COG1523	belongs to the glycosyl hydrolase 13 family
WR51_14210	COG3227	Zinc metalloprotease (Elastase)
WR51_14215	COG0737	Belongs to the 5'-nucleotidase family
WR51_14230	COG0201	protein transport
WR51_14245	COG0697	spore germination
WR51_14250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_14260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR51_14290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_14305	COG2959	enzyme of heme biosynthesis
WR51_14310	COG3773	Cell wall hydrolase
WR51_14310	COG3409	Peptidoglycan-binding domain 1 protein
WR51_14345	COG1309	transcriptional regulator
WR51_14375	COG3284	Transcriptional regulator
WR51_14395	COG1349	DNA-binding transcription factor activity
WR51_14410	COG1959	2 iron, 2 sulfur cluster binding
WR51_14425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_14430	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_14435	COG0022	dehydrogenase e1 component
WR51_14440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_14450	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_14455	COG0456	acetyltransferase
WR51_14455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_14495	COG4176	ABC-type proline glycine betaine transport system permease component
WR51_14500	COG0517	IMP dehydrogenase activity
WR51_14500	COG4175	Glycine betaine
WR51_14510	COG0740	serine-type endopeptidase activity
WR51_14530	COG2153	protein acetylation
WR51_14535	COG3397	chitin binding
WR51_14540	COG1819	glycosyl
WR51_14565	COG2315	Protein conserved in bacteria
WR51_14610	COG0456	acetyltransferase
WR51_14615	COG3973	AAA domain
WR51_14630	COG0514	ATP-dependent DNA helicase (RecQ)
WR51_14655	COG2801	Transposase and inactivated derivatives
WR51_14670	COG4637	Psort location Cytoplasmic, score
WR51_14690	COG3397	chitin binding
WR51_14705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WR51_14710	COG1115	amino acid carrier protein
WR51_14715	COG1012	belongs to the aldehyde dehydrogenase family
WR51_14720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WR51_14730	COG3938	Belongs to the proline racemase family
WR51_14735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_14775	COG0586	Pfam SNARE associated Golgi protein
WR51_14785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR51_14790	COG4166	transmembrane transport
WR51_14800	COG4948	Mandelate Racemase Muconate Lactonizing
WR51_14815	COG0667	Aldo Keto reductase
WR51_14855	COG3850	Histidine kinase
WR51_14855	COG5002	protein histidine kinase activity
WR51_14860	COG0745	RESPONSE REGULATOR receiver
WR51_14900	COG1164	Oligoendopeptidase f
WR51_14905	COG1307	EDD domain protein, DegV family
WR51_14945	COG2814	Major facilitator Superfamily
WR51_14955	COG1664	Polymer-forming cytoskeletal
WR51_14960	COG0789	Transcriptional regulator
WR51_14965	COG4533	DNA binding
WR51_14970	COG0477	Major facilitator Superfamily
WR51_14970	COG2814	Major facilitator Superfamily
WR51_14995	COG2261	transglycosylase associated protein
WR51_15010	COG2226	methyltransferase
WR51_15050	COG0436	Aminotransferase
WR51_15055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WR51_15065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WR51_15080	COG1131	(ABC) transporter
WR51_15155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_15160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_15205	COG2746	aminoglycoside 3-N-acetyltransferase activity
WR51_15215	COG0697	spore germination
WR51_15240	COG4912	Dna alkylation repair
WR51_15245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_15250	COG0346	lactoylglutathione lyase activity
WR51_15255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_15265	COG0726	polysaccharide deacetylase
WR51_15270	COG3037	sugar-specific permease SgaT UlaA
WR51_15280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_15285	COG0861	Integral membrane protein TerC family
WR51_15290	COG1368	sulfuric ester hydrolase activity
WR51_15295	COG0488	(ABC) transporter
WR51_15300	COG1033	growth of symbiont in host cell
WR51_15300	COG2409	Drug exporters of the RND superfamily
WR51_15305	COG1309	transcriptional regulator
WR51_15310	COG1051	belongs to the nudix hydrolase family
WR51_15325	COG0287	Prephenate dehydrogenase
WR51_15340	COG1605	Chorismate mutase
WR51_15340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_15385	COG3584	3D domain protein
WR51_15385	COG1388	LysM domain
WR51_15395	COG0277	FAD linked oxidase domain protein
WR51_15420	COG1879	ABC-type sugar transport system periplasmic component
WR51_15425	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_15430	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_15440	COG2390	Transcriptional regulator
WR51_15445	COG1070	Carbohydrate kinase
WR51_15465	COG2329	Antibiotic biosynthesis monooxygenase
WR51_15480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_15495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_15500	COG4187	Peptidase family M20/M25/M40
WR51_15505	COG1414	Transcriptional regulator
WR51_15510	COG0833	amino acid
WR51_15525	COG3239	Fatty acid desaturase
WR51_15535	COG2720	vancomycin resistance protein
WR51_15540	COG1785	Belongs to the alkaline phosphatase family
WR51_15550	COG3655	Transcriptional regulator
WR51_15575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_15580	COG0346	lactoylglutathione lyase activity
WR51_15605	COG0714	Associated with various cellular activities
WR51_15625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WR51_15630	COG0753	catalase activity
WR51_15665	COG0778	Nitroreductase
WR51_15670	COG1846	Transcriptional regulator
WR51_15705	COG1725	Transcriptional regulator
WR51_15710	COG4282	regulation of fungal-type cell wall biogenesis
WR51_15735	COG0456	acetyltransferase
WR51_15750	COG0697	spore germination
WR51_15755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_15795	COG0730	response to heat
WR51_15805	COG0833	amino acid
WR51_15815	COG4335	DNA alkylation repair
WR51_15880	COG1984	allophanate hydrolase subunit 2
WR51_15885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WR51_15890	COG1414	Transcriptional regulator
WR51_15905	COG3142	Participates in the control of copper homeostasis
WR51_15910	COG0640	Transcriptional regulator
WR51_15920	COG1960	acyl-CoA dehydrogenase activity
WR51_15955	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
WR51_15980	COG3848	Pyruvate phosphate dikinase
WR51_15980	COG0574	Belongs to the PEP-utilizing enzyme family
WR51_15985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_16005	COG1063	alcohol dehydrogenase
WR51_16015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR51_16040	COG0737	Belongs to the 5'-nucleotidase family
WR51_16045	COG2267	carboxylic ester hydrolase activity
WR51_16050	COG1335	isochorismatase
WR51_16070	COG0583	DNA-binding transcription factor activity
WR51_16075	COG1846	Transcriptional regulator
WR51_16080	COG0598	Magnesium transport protein CorA
WR51_16120	COG0415	Belongs to the DNA photolyase family
WR51_16135	COG0288	reversible hydration of carbon dioxide
WR51_16145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR51_16150	COG5609	conserved protein (DUF2294)
WR51_16155	COG0726	polysaccharide deacetylase
WR51_16165	COG1575	Belongs to the MenA family. Type 1 subfamily
WR51_16185	COG0798	PFAM Bile acid sodium symporter
WR51_16190	COG0346	lactoylglutathione lyase activity
WR51_16195	COG0640	Transcriptional regulator
WR51_16215	COG2169	Transcriptional regulator
WR51_16235	COG2814	Major facilitator Superfamily
WR51_16240	COG1309	transcriptional regulator
WR51_16245	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_16250	COG1522	sequence-specific DNA binding
WR51_16265	COG0346	lactoylglutathione lyase activity
WR51_16295	COG0814	amino acid
WR51_16300	COG0583	DNA-binding transcription factor activity
WR51_16330	COG1131	(ABC) transporter
WR51_16335	COG1725	Transcriptional regulator
WR51_16380	COG0745	RESPONSE REGULATOR receiver
WR51_16385	COG3850	Histidine kinase
WR51_16385	COG5002	protein histidine kinase activity
WR51_16425	COG1136	(ABC) transporter
WR51_16460	COG2814	Major facilitator Superfamily
WR51_16485	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WR51_16495	COG1690	Belongs to the RtcB family
WR51_16505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
WR51_16525	COG0577	efflux transmembrane transporter activity
WR51_16545	COG3850	Histidine kinase
WR51_16545	COG5002	protein histidine kinase activity
WR51_16555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_16565	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_16585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WR51_16605	COG0662	Cupin 2, conserved barrel domain protein
WR51_16610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_16610	COG2207	Transcriptional regulator
WR51_16630	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_16630	COG3409	Peptidoglycan-binding domain 1 protein
WR51_16640	COG2814	Major facilitator Superfamily
WR51_16660	COG1876	peptidase activity
WR51_16665	COG2843	Capsule synthesis protein
WR51_16675	COG0477	Major facilitator Superfamily
WR51_16690	COG1846	Transcriptional regulator
WR51_16695	COG2814	Major facilitator Superfamily
WR51_16705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR51_16710	COG1131	(ABC) transporter
WR51_16730	COG2076	Multidrug Resistance protein
WR51_16735	COG1309	transcriptional regulator
WR51_16755	COG2031	fatty acid transporter
WR51_16765	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_16800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR51_16820	COG1288	antiporter activity
WR51_16825	COG2356	endonuclease I
WR51_16855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WR51_16875	COG1733	regulation of RNA biosynthetic process
WR51_16880	COG0778	Nitroreductase
WR51_16910	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_16920	COG1131	(ABC) transporter
WR51_16950	COG1011	Hydrolase
WR51_16985	COG0346	lactoylglutathione lyase activity
WR51_16990	COG1940	carbohydrate kinase activity
WR51_17000	COG0110	maltose O-acetyltransferase activity
WR51_17005	COG0180	Tryptophanyl-tRNA synthetase
WR51_17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_17030	COG0628	permease
WR51_17050	COG0500	methyltransferase
WR51_17060	COG0477	Major facilitator Superfamily
WR51_17100	COG1253	flavin adenine dinucleotide binding
WR51_17105	COG0789	Transcriptional regulator
WR51_17115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_17140	COG0697	spore germination
WR51_17150	COG1357	PFAM Pentapeptide repeats (8 copies)
WR51_17155	COG3813	Protein conserved in bacteria
WR51_17160	COG2706	6-phosphogluconolactonase activity
WR51_17165	COG1070	Carbohydrate kinase
WR51_17180	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR51_17185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WR51_17190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR51_17195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR51_17230	COG0814	amino acid
WR51_17260	COG2188	Transcriptional regulator
WR51_17265	COG0673	inositol 2-dehydrogenase activity
WR51_17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_17305	COG0384	phenazine biosynthesis protein PhzF
WR51_17320	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_17325	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_17330	COG1733	regulation of RNA biosynthetic process
WR51_17335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR51_17350	COG2801	Transposase and inactivated derivatives
WR51_17360	COG0726	polysaccharide deacetylase
WR51_17370	COG1191	sigma factor activity
WR51_17405	COG1280	lysine exporter protein (LysE YggA)
WR51_17450	COG1151	hydroxylamine reductase activity
WR51_17460	COG3757	hydrolase, family 25
WR51_17460	COG3409	Peptidoglycan-binding domain 1 protein
WR51_17495	COG2072	flavoprotein involved in K transport
WR51_17530	COG0604	alcohol dehydrogenase
WR51_17535	COG1113	amino acid transport
WR51_17540	COG2814	Major facilitator Superfamily
WR51_17570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
WR51_17575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_17590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_17595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_17600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_17605	COG3739	integral membrane protein
WR51_17625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_17640	COG0583	DNA-binding transcription factor activity
WR51_17675	COG2162	N-hydroxyarylamine O-acetyltransferase activity
WR51_17680	COG1164	Oligoendopeptidase f
WR51_17710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_17735	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_17780	COG0640	Transcriptional regulator
WR51_17785	COG0604	alcohol dehydrogenase
WR51_17795	COG0457	Tetratricopeptide repeat
WR51_17805	COG2808	Putative FMN-binding domain
WR51_17820	COG0277	FAD linked oxidase domain protein
WR51_17835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_17835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_17840	COG1252	NADH dehydrogenase
WR51_17855	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_17890	COG0823	Involved in the tonB-independent uptake of proteins
WR51_17895	COG3397	chitin binding
WR51_17905	COG0697	spore germination
WR51_17925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_17935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_17950	COG0457	Tetratricopeptide repeat
WR51_17975	COG1404	Belongs to the peptidase S8 family
WR51_18000	COG5001	Diguanylate cyclase
WR51_18000	COG3300	MHYT domain
WR51_18010	COG1309	transcriptional regulator
WR51_18025	COG1876	peptidase activity
WR51_18050	COG3852	Histidine kinase
WR51_18060	COG1285	pathogenesis
WR51_18070	COG2514	catechol 2,3-dioxygenase activity
WR51_18075	COG2720	vancomycin resistance protein
WR51_18105	COG1278	Cold shock
WR51_18115	COG0716	FMN binding
WR51_18125	COG1051	belongs to the nudix hydrolase family
WR51_18145	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_18155	COG0165	Argininosuccinate lyase
WR51_18170	COG4145	pantothenate transmembrane transporter activity
WR51_18180	COG1012	belongs to the aldehyde dehydrogenase family
WR51_18185	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_18195	COG1657	PFAM Prenyltransferase squalene oxidase
WR51_18200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
WR51_18205	COG2962	Rard protein
WR51_18210	COG3326	Membrane
WR51_18225	COG0489	protein tyrosine kinase activity
WR51_18235	COG0314	molybdopterin synthase activity
WR51_18240	COG0303	'Molybdopterin
WR51_18245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_18250	COG2116	formate transmembrane transporter activity
WR51_18260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR51_18265	COG5609	conserved protein (DUF2294)
WR51_18270	COG2427	Protein of unknown function (DUF1641)
WR51_18275	COG3383	formate dehydrogenase (NAD+) activity
WR51_18285	COG0697	spore germination
WR51_18300	COG0531	amino acid
WR51_18335	COG2226	methyltransferase
WR51_18340	COG4166	transmembrane transport
WR51_18350	COG2801	Transposase and inactivated derivatives
WR51_18355	COG4166	transmembrane transport
WR51_18360	COG4166	transmembrane transport
WR51_18365	COG1316	TRANSCRIPTIONal
WR51_18375	COG1595	DNA-templated transcription, initiation
WR51_18385	COG1131	(ABC) transporter
WR51_18405	COG0673	inositol 2-dehydrogenase activity
WR51_18410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR51_18415	COG0187	DNA topoisomerase II activity
WR51_18425	COG1832	CoA-binding protein
WR51_18430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_18435	COG0745	RESPONSE REGULATOR receiver
WR51_18455	COG4841	protein insertion into membrane
WR51_18460	COG0824	Thioesterase
WR51_18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_18495	COG2274	protein secretion by the type I secretion system
WR51_18500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WR51_18510	COG0726	polysaccharide deacetylase
WR51_18530	COG2211	Major facilitator Superfamily
WR51_18540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR51_18555	COG0183	Belongs to the thiolase family
WR51_18560	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_18565	COG1268	BioY protein
WR51_18570	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_18580	COG5002	protein histidine kinase activity
WR51_18595	COG1136	(ABC) transporter
WR51_18610	COG1131	(ABC) transporter
WR51_18700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_18710	COG5002	protein histidine kinase activity
WR51_18715	COG0400	carboxylic ester hydrolase activity
WR51_18720	COG0346	lactoylglutathione lyase activity
WR51_18725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_18730	COG0069	glutamate synthase activity
WR51_18735	COG1902	pentaerythritol trinitrate reductase activity
WR51_18740	COG1329	Transcriptional regulator
WR51_18745	COG0010	Belongs to the arginase family
WR51_18770	COG2226	methyltransferase
WR51_18800	COG4846	Membrane protein involved in cytochrome C biogenesis
WR51_18805	COG0785	Cytochrome C biogenesis protein
WR51_18825	COG1131	(ABC) transporter
WR51_18840	COG0583	DNA-binding transcription factor activity
WR51_18850	COG1346	cytolysis
WR51_18865	COG0730	response to heat
WR51_18890	COG1132	(ABC) transporter
WR51_18895	COG1132	(ABC) transporter
WR51_18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_18935	COG0737	Belongs to the 5'-nucleotidase family
WR51_18945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WR51_18965	COG1695	Transcriptional regulator
WR51_18975	COG1388	LysM domain
WR51_18975	COG3409	Peptidoglycan-binding domain 1 protein
WR51_18975	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_19015	COG0174	glutamine synthetase
WR51_19020	COG0789	Transcriptional regulator
WR51_19025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
WR51_19030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR51_19035	COG2860	membrane
WR51_19045	COG0464	growth
WR51_19075	COG3584	3D domain protein
WR51_19075	COG1388	LysM domain
WR51_19080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR51_19080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_19080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR51_19085	COG1105	Belongs to the carbohydrate kinase PfkB family
WR51_19090	COG1349	DNA-binding transcription factor activity
WR51_19095	COG1979	alcohol dehydrogenase
WR51_19100	COG2322	membrane
WR51_19115	COG1113	amino acid transport
WR51_19130	COG1408	metallophosphoesterase
WR51_19135	COG2116	formate transmembrane transporter activity
WR51_19150	COG2217	Heavy metal translocating P-type atpase
WR51_19155	COG2608	mercury ion transmembrane transporter activity
WR51_19160	COG2801	Transposase and inactivated derivatives
WR51_19170	COG1937	Protein conserved in bacteria
WR51_19180	COG2819	hydrolase of the alpha beta superfamily
WR51_19185	COG1120	ATPase activity
WR51_19190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_19195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_19200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_19205	COG0708	Exodeoxyribonuclease III
WR51_19210	COG2169	Transcriptional regulator
WR51_19215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR51_19220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR51_19230	COG2364	Membrane
WR51_19245	COG2267	carboxylic ester hydrolase activity
WR51_19250	COG3300	MHYT domain
WR51_19250	COG5001	Diguanylate cyclase
WR51_19270	COG1086	Polysaccharide biosynthesis protein
WR51_19290	COG1346	cytolysis
WR51_19300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_19310	COG2188	Transcriptional regulator
WR51_19315	COG2723	6-phospho-beta-galactosidase activity
WR51_19325	COG1404	Belongs to the peptidase S8 family
WR51_19330	COG3773	Cell wall hydrolase
WR51_19340	COG1368	sulfuric ester hydrolase activity
WR51_19345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_19370	COG4550	Control of competence regulator ComK, YlbF/YmcA
WR51_19380	COG1013	pyruvate-flavodoxin oxidoreductase activity
WR51_19385	COG0674	pyruvate-flavodoxin oxidoreductase activity
WR51_19385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WR51_19395	COG2359	stage V sporulation protein S
WR51_19400	COG1692	metallophosphoesterase
WR51_19425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WR51_19430	COG1426	Protein conserved in bacteria
WR51_19445	COG0300	oxidoreductase activity
WR51_19450	COG0612	Peptidase, M16
WR51_19455	COG0612	Peptidase, M16
WR51_19480	COG2188	Transcriptional regulator
WR51_19500	COG0740	serine-type endopeptidase activity
WR51_19505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_19515	COG0527	aspartate kinase activity
WR51_19520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR51_19525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR51_19540	COG5444	nuclease activity
WR51_19550	COG0582	viral genome integration into host DNA
WR51_19600	COG0305	Participates in initiation and elongation during chromosome replication
WR51_19660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR51_19665	COG1873	PFAM PRC-barrel domain
WR51_19670	COG0612	Peptidase, M16
WR51_19675	COG0726	polysaccharide deacetylase
WR51_19690	COG0196	riboflavin kinase activity
WR51_19705	COG1550	Protein conserved in bacteria
WR51_19715	COG1358	cellular component organization or biogenesis
WR51_19720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
WR51_19725	COG0195	Participates in both transcription termination and antitermination
WR51_19745	COG0750	zinc metalloprotease
WR51_19755	COG4589	Belongs to the CDS family
WR51_19800	COG4974	Belongs to the 'phage' integrase family
WR51_19810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WR51_19815	COG0758	DNA mediated transformation
WR51_19820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WR51_19860	COG1837	Belongs to the UPF0109 family
WR51_19870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WR51_19880	COG0552	protein localization to endoplasmic reticulum
WR51_19885	COG1196	nuclear chromosome segregation
WR51_19900	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_19905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WR51_19920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WR51_19925	COG1461	Dihydroxyacetone kinase
WR51_19930	COG1302	Protein conserved in bacteria
WR51_19945	COG1564	THIamine pyrophosphokinase
WR51_19950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WR51_19960	COG0515	serine threonine protein kinase
WR51_19960	COG2815	serine threonine protein kinase
WR51_19965	COG0631	protein serine/threonine phosphatase activity
WR51_19975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WR51_19975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WR51_19990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WR51_19995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR51_20015	COG1561	YicC-like family, N-terminal region
WR51_20020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WR51_20035	COG0006	proline dipeptidase activity
WR51_20055	COG3069	C4-dicarboxylate transmembrane transporter activity
WR51_20120	COG0564	pseudouridine synthase activity
WR51_20140	COG3599	regulation of cell shape
WR51_20145	COG2302	S4 RNA-binding domain
WR51_20150	COG0762	integral membrane protein
WR51_20160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WR51_20170	COG1873	PFAM PRC-barrel domain
WR51_20175	COG1191	sigma factor activity
WR51_20180	COG1191	sigma factor activity
WR51_20190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WR51_20195	COG0849	cell division
WR51_20210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WR51_20215	COG0772	Belongs to the SEDS family
WR51_20235	COG0768	penicillin binding
WR51_20260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR51_20280	COG1399	metal-binding, possibly nucleic acid-binding protein
WR51_20290	COG3480	Lon protease (S16) C-terminal proteolytic domain
WR51_20295	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR51_20300	COG3314	Sporulation integral membrane protein YlbJ
WR51_20310	COG0742	ribosomal rna small subunit methyltransferase
WR51_20325	COG3679	Belongs to the UPF0342 family
WR51_20330	COG0406	alpha-ribazole phosphatase activity
WR51_20345	COG2340	Cysteine-rich secretory protein family
WR51_20360	COG3336	cytochrome c oxidase
WR51_20395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
WR51_20400	COG0772	Belongs to the SEDS family
WR51_20410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WR51_20415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WR51_20425	COG4896	Protein conserved in bacteria
WR51_20450	COG0483	inositol monophosphate 1-phosphatase activity
WR51_20470	COG1982	Orn Lys Arg decarboxylase major
WR51_20520	COG0022	dehydrogenase e1 component
WR51_20525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_20540	COG0561	phosphatase activity
WR51_20550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_20555	COG0569	domain protein
WR51_20575	COG0583	DNA-binding transcription factor activity
WR51_20580	COG0517	IMP dehydrogenase activity
WR51_20590	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
WR51_20600	COG4703	Protein of unknown function (DUF1797)
WR51_20615	COG2200	EAL domain
WR51_20620	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_20625	COG1408	metallophosphoesterase
WR51_20670	COG2814	Major facilitator Superfamily
WR51_20695	COG3209	COG3209 Rhs family protein
WR51_20705	COG2205	protein histidine kinase activity
WR51_20715	COG0436	Aminotransferase
WR51_20720	COG1609	Transcriptional regulator
WR51_20725	COG3833	ABC-type maltose transport systems, permease component
WR51_20730	COG1175	transmembrane transport
WR51_20735	COG2182	Extracellular solute-binding protein
WR51_20745	COG0366	Alpha amylase catalytic
WR51_20750	COG3842	ATPase activity
WR51_20790	COG0183	Belongs to the thiolase family
WR51_20825	COG1695	Transcriptional regulator
WR51_20830	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_20850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WR51_20855	COG0436	Aminotransferase
WR51_20890	COG2084	Dehydrogenase
WR51_20900	COG2199	diguanylate cyclase activity
WR51_20900	COG2203	Gaf domain
WR51_20905	COG0778	Nitroreductase
WR51_20930	COG2190	(PTS) system
WR51_20930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_20930	COG1263	PTS System
WR51_20935	COG3711	transcriptional antiterminator
WR51_20955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WR51_20985	COG1547	Domain of unknown function (DUF309)
WR51_20990	COG0456	acetyltransferase
WR51_20995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WR51_21000	COG4086	secreted protein
WR51_21005	COG0561	phosphatase activity
WR51_21010	COG0697	spore germination
WR51_21025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_21050	COG0733	neurotransmitter:sodium symporter activity
WR51_21070	COG1686	Belongs to the peptidase S11 family
WR51_21075	COG1725	Transcriptional regulator
WR51_21080	COG1131	(ABC) transporter
WR51_21095	COG1846	Transcriptional regulator
WR51_21110	COG0598	Magnesium transport protein CorA
WR51_21135	COG4974	Belongs to the 'phage' integrase family
WR51_21145	COG0735	belongs to the Fur family
WR51_21150	COG1300	Membrane
WR51_21170	COG0667	Aldo Keto reductase
WR51_21175	COG0656	L-ascorbic acid biosynthetic process
WR51_21180	COG0456	acetyltransferase
WR51_21180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_21190	COG4085	toxin activity
WR51_21190	COG0737	Belongs to the 5'-nucleotidase family
WR51_21190	COG1525	nuclease
WR51_21200	COG0596	Alpha beta hydrolase
WR51_21205	COG2056	Na+-H+ antiporter family
WR51_21210	COG1609	Transcriptional regulator
WR51_21215	COG0456	acetyltransferase
WR51_21220	COG1073	alpha beta
WR51_21235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR51_21235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR51_21240	COG0307	riboflavin synthase, alpha
WR51_21270	COG1073	alpha beta
WR51_21270	COG2226	methyltransferase
WR51_21285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_21300	COG0737	Belongs to the 5'-nucleotidase family
WR51_21310	COG1522	sequence-specific DNA binding
WR51_21350	COG5444	nuclease activity
WR51_21385	COG0300	oxidoreductase activity
WR51_21390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_21395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_21400	COG1760	l-serine dehydratase
WR51_21405	COG1760	l-serine dehydratase
WR51_21440	COG1285	pathogenesis
WR51_21455	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR51_21460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_21475	COG1376	ErfK ybiS ycfS ynhG family protein
WR51_21480	COG4129	membrane
WR51_21485	COG1126	abc transporter atp-binding protein
WR51_21490	COG0765	amino acid transport
WR51_21495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_21520	COG2323	membrane
WR51_21525	COG0772	Belongs to the SEDS family
WR51_21535	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_21540	COG0022	dehydrogenase e1 component
WR51_21545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_21550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_21560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WR51_21565	COG0280	phosphate acetyltransferase
WR51_21575	COG3290	protein histidine kinase activity
WR51_21575	COG3829	transcription factor binding
WR51_21585	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_21590	COG3093	addiction module antidote protein HigA
WR51_21610	COG0750	zinc metalloprotease
WR51_21615	COG0497	DNA recombination
WR51_21625	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WR51_21635	COG0142	geranyltranstransferase activity
WR51_21660	COG1302	Protein conserved in bacteria
WR51_21665	COG0439	Biotin carboxylase
WR51_21670	COG0511	ligase activity, forming carbon-carbon bonds
WR51_21715	COG3854	ATPases associated with a variety of cellular activities
WR51_21740	COG0006	proline dipeptidase activity
WR51_21755	COG3872	metal-dependent enzyme
WR51_21765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WR51_21800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_21810	COG1609	Transcriptional regulator
WR51_21820	COG2076	Multidrug Resistance protein
WR51_21825	COG2076	Multidrug Resistance protein
WR51_21865	COG1725	Transcriptional regulator
WR51_21895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_21960	COG1459	type II secretion system
WR51_21965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WR51_22030	COG1410	methionine synthase
WR51_22030	COG0646	methionine synthase
WR51_22035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WR51_22035	COG0646	methionine synthase
WR51_22040	COG0626	cystathionine gamma-synthase activity
WR51_22045	COG0626	cystathionine gamma-synthase activity
WR51_22065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_22075	COG1940	carbohydrate kinase activity
WR51_22080	COG4483	Protein conserved in bacteria
WR51_22085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WR51_22095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_22100	COG0704	Plays a role in the regulation of phosphate uptake
WR51_22110	COG0573	inorganic phosphate transmembrane transporter activity
WR51_22115	COG0573	inorganic phosphate transmembrane transporter activity
WR51_22120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR51_22130	COG0477	Major facilitator Superfamily
WR51_22135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR51_22145	COG5521	maltodextrose utilization protein MalA
WR51_22160	COG0735	belongs to the Fur family
WR51_22165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WR51_22170	COG1121	(ABC) transporter
WR51_22175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_22205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WR51_22210	COG2384	SAM-dependent methyltransferase
WR51_22220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WR51_22225	COG0358	DNA primase activity
WR51_22240	COG0517	IMP dehydrogenase activity
WR51_22255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WR51_22260	COG0295	cytidine deaminase activity
WR51_22265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WR51_22275	COG1480	7TM receptor with intracellular HD hydrolase
WR51_22280	COG1702	phosphate starvation-inducible protein PhoH
WR51_22300	COG1610	YqeY-like protein
WR51_22310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WR51_22315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WR51_22345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR51_22350	COG1733	regulation of RNA biosynthetic process
WR51_22375	COG1466	dna polymerase III delta subunit
WR51_22385	COG2333	competence protein COMEC
WR51_22385	COG0658	competence protein
WR51_22390	COG2131	deaminase
WR51_22395	COG1596	polysaccharide export
WR51_22395	COG1555	photosystem II stabilization
WR51_22400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_22405	COG2226	methyltransferase
WR51_22410	COG0799	negative regulation of ribosome biogenesis
WR51_22415	COG1713	HD superfamily hydrolase involved in NAD metabolism
WR51_22425	COG1534	Rna-binding protein
WR51_22435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WR51_22440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
WR51_22455	COG1191	sigma factor activity
WR51_22465	COG1595	DNA-templated transcription, initiation
WR51_22475	COG0778	Nitroreductase
WR51_22480	COG2357	RelA SpoT domain protein
WR51_22490	COG1785	Belongs to the alkaline phosphatase family
WR51_22500	COG2267	carboxylic ester hydrolase activity
WR51_22540	COG3186	Phenylalanine-4-hydroxylase
WR51_22550	COG2514	catechol 2,3-dioxygenase activity
WR51_22555	COG2259	Doxx family
WR51_22595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_22605	COG1012	belongs to the aldehyde dehydrogenase family
WR51_22605	COG1454	alcohol dehydrogenase
WR51_22610	COG0626	cystathionine gamma-synthase activity
WR51_22615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_22640	COG0768	penicillin binding
WR51_22670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WR51_22700	COG0628	permease
WR51_22720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WR51_22735	COG1104	cysteine desulfurase activity
WR51_22740	COG1959	2 iron, 2 sulfur cluster binding
WR51_22745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WR51_22760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WR51_22785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WR51_22795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WR51_22795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
WR51_22800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR51_22805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR51_22805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR51_22815	COG2244	polysaccharide biosynthetic process
WR51_22820	COG2323	membrane
WR51_22830	COG1862	Preprotein translocase
WR51_22860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
WR51_22890	COG0157	Belongs to the NadC ModD family
WR51_22900	COG1104	cysteine desulfurase activity
WR51_22905	COG1827	regulation of RNA biosynthetic process
WR51_22910	COG2258	MOSC domain
WR51_22915	COG0077	Prephenate dehydratase
WR51_22920	COG0577	efflux transmembrane transporter activity
WR51_22925	COG0577	efflux transmembrane transporter activity
WR51_22930	COG1136	(ABC) transporter
WR51_22935	COG5002	protein histidine kinase activity
WR51_22940	COG0745	RESPONSE REGULATOR receiver
WR51_22950	COG3290	protein histidine kinase activity
WR51_22960	COG2868	ribosomal protein
WR51_22970	COG1530	ribonuclease E activity
WR51_22975	COG1994	Peptidase M50
WR51_22980	COG0739	heme binding
WR51_22985	COG2894	cell division
WR51_23000	COG1792	Involved in formation and maintenance of cell shape
WR51_23005	COG1077	Cell shape determining protein MreB Mrl
WR51_23025	COG0285	dihydrofolate synthase activity
WR51_23040	COG1388	LysM domain
WR51_23050	COG0113	porphobilinogen synthase activity
WR51_23055	COG1587	Uroporphyrinogen-III synthase
WR51_23065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR51_23075	COG1846	Transcriptional regulator
WR51_23080	COG1764	response to oxidative stress
WR51_23095	COG1067	ATP-dependent peptidase activity
WR51_23095	COG0470	DNA polymerase III
WR51_23145	COG0622	Phosphoesterase
WR51_23160	COG5401	PFAM Sporulation and spore germination
WR51_23180	COG1309	transcriptional regulator
WR51_23190	COG2197	response regulator
WR51_23195	COG2233	PERMEase
WR51_23200	COG0402	S-adenosylhomocysteine deaminase activity
WR51_23205	COG1983	PspC domain protein
WR51_23210	COG1396	sequence-specific DNA binding
WR51_23215	COG0697	spore germination
WR51_23225	COG1959	2 iron, 2 sulfur cluster binding
WR51_23230	COG1668	transmembrane transport
WR51_23235	COG4152	abc transporter atp-binding protein
WR51_23240	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
WR51_23245	COG1360	Flagellar Motor Protein
WR51_23250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR51_23255	COG1876	peptidase activity
WR51_23260	COG0824	Thioesterase
WR51_23265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WR51_23270	COG1053	succinate dehydrogenase
WR51_23275	COG2009	succinate dehydrogenase
WR51_23280	COG1719	4-vinyl reductase, 4VR
WR51_23290	COG3118	belongs to the thioredoxin family
WR51_23295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WR51_23300	COG2086	electron transfer activity
WR51_23305	COG1024	Enoyl-CoA hydratase
WR51_23310	COG1309	transcriptional regulator
WR51_23315	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_23340	COG2318	DinB family
WR51_23370	COG1131	(ABC) transporter
WR51_23375	COG2205	protein histidine kinase activity
WR51_23380	COG0745	RESPONSE REGULATOR receiver
WR51_23390	COG4895	conserved protein (DUF2196)
WR51_23395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WR51_23405	COG4509	Sortase family
WR51_23410	COG1120	ATPase activity
WR51_23425	COG5386	Cell surface protein
WR51_23435	COG5386	Cell surface protein
WR51_23440	COG1114	Component of the transport system for branched-chain amino acids
WR51_23445	COG1187	pseudouridine synthase activity
WR51_23460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR51_23460	COG1796	DNA polymerase
WR51_23465	COG1286	toxin biosynthetic process
WR51_23510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR51_23520	COG1418	mRNA catabolic process
WR51_23540	COG2814	Major facilitator Superfamily
WR51_23545	COG1566	PFAM secretion protein HlyD family protein
WR51_23550	COG1309	transcriptional regulator
WR51_23555	COG1363	Peptidase, m42
WR51_23580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR51_23595	COG1484	DNA-dependent DNA replication
WR51_23600	COG3611	Membrane attachment protein
WR51_23610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WR51_23615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR51_23620	COG0237	dephospho-CoA kinase activity
WR51_23625	COG1971	Probably functions as a manganese efflux pump
WR51_23635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_23635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_23640	COG5002	protein histidine kinase activity
WR51_23645	COG0745	RESPONSE REGULATOR receiver
WR51_23665	COG0538	isocitrate dehydrogenase activity
WR51_23670	COG0372	Belongs to the citrate synthase family
WR51_23685	COG0628	permease
WR51_23690	COG3030	protein affecting phage T7 exclusion by the F plasmid
WR51_23715	COG1725	Transcriptional regulator
WR51_23720	COG0281	malic enzyme
WR51_23725	COG0587	DNA-directed DNA polymerase activity
WR51_23740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WR51_23755	COG4109	DRTGG domain
WR51_23770	COG0006	proline dipeptidase activity
WR51_23805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_23810	COG0662	Cupin 2, conserved barrel domain protein
WR51_23825	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_23830	COG0589	response to stress
WR51_23870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_23895	COG0827	DNA restriction-modification system
WR51_23900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WR51_23905	COG3874	Sporulation protein YtfJ
WR51_23920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WR51_23930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_23945	COG1104	cysteine desulfurase activity
WR51_23965	COG1136	(ABC) transporter
WR51_23990	COG0583	DNA-binding transcription factor activity
WR51_23995	COG0697	spore germination
WR51_24000	COG1309	transcriptional regulator
WR51_24005	COG1956	GAF domain-containing protein
WR51_24010	COG0626	cystathionine gamma-synthase activity
WR51_24040	COG1595	DNA-templated transcription, initiation
WR51_24050	COG0110	maltose O-acetyltransferase activity
WR51_24055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_24060	COG0454	-acetyltransferase
WR51_24065	COG0517	IMP dehydrogenase activity
WR51_24070	COG0123	including yeast histone deacetylase and acetoin utilization protein
WR51_24075	COG2267	carboxylic ester hydrolase activity
WR51_24085	COG0745	RESPONSE REGULATOR receiver
WR51_24090	COG5002	protein histidine kinase activity
WR51_24095	COG0666	response to abiotic stimulus
WR51_24125	COG1609	Transcriptional regulator
WR51_24135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_24135	COG1605	Chorismate mutase
WR51_24140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_24140	COG1605	Chorismate mutase
WR51_24145	COG4851	CamS sex pheromone cAM373 precursor
WR51_24150	COG3118	belongs to the thioredoxin family
WR51_24160	COG2309	aminopeptidase activity
WR51_24180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_24185	COG0697	spore germination
WR51_24190	COG0789	Transcriptional regulator
WR51_24205	COG1674	ftsk spoiiie
WR51_24210	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_24220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR51_24230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_24235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
WR51_24240	COG1363	Peptidase, m42
WR51_24250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_24265	COG0510	thiamine kinase activity
WR51_24270	COG1523	belongs to the glycosyl hydrolase 13 family
WR51_24285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_24290	COG1349	DNA-binding transcription factor activity
WR51_24295	COG1187	pseudouridine synthase activity
WR51_24300	COG2244	polysaccharide biosynthetic process
WR51_24305	COG2081	HI0933 family
WR51_24310	COG2814	Major facilitator Superfamily
WR51_24320	COG3832	glyoxalase III activity
WR51_24340	COG1329	Transcriptional regulator
WR51_24365	COG0314	molybdopterin synthase activity
WR51_24370	COG1763	Mo-molybdopterin cofactor biosynthetic process
WR51_24375	COG0303	'Molybdopterin
WR51_24385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_24390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR51_24410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_24420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR51_24460	COG2814	Major facilitator Superfamily
WR51_24465	COG0475	glutathione-regulated potassium exporter activity
WR51_24470	COG0490	domain, Protein
WR51_24475	COG0582	viral genome integration into host DNA
WR51_24485	COG1136	(ABC) transporter
WR51_24505	COG1242	4 iron, 4 sulfur cluster binding
WR51_24510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
WR51_24525	COG1794	racemase activity, acting on amino acids and derivatives
WR51_24545	COG2267	carboxylic ester hydrolase activity
WR51_24550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WR51_24555	COG0671	phosphoesterase, PA-phosphatase related
WR51_24560	COG0438	transferase activity, transferring glycosyl groups
WR51_24650	COG5002	protein histidine kinase activity
WR51_24655	COG3852	Histidine kinase
WR51_24665	COG2267	carboxylic ester hydrolase activity
WR51_24670	COG1368	sulfuric ester hydrolase activity
WR51_24690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_24695	COG1116	anion transmembrane transporter activity
WR51_24700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_24715	COG0546	phosphoglycolate phosphatase activity
WR51_24725	COG0494	nUDIX hydrolase
WR51_24765	COG0288	reversible hydration of carbon dioxide
WR51_24770	COG1271	oxidase subunit
WR51_24775	COG1294	oxidase, subunit
WR51_24790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_24810	COG1842	Phage shock protein A
WR51_24835	COG3859	Proton-coupled thiamine transporter YuaJ
WR51_24840	COG5002	protein histidine kinase activity
WR51_24845	COG0745	RESPONSE REGULATOR receiver
WR51_24875	COG1597	lipid kinase activity
WR51_24905	COG0586	Pfam SNARE associated Golgi protein
WR51_24915	COG0577	efflux transmembrane transporter activity
WR51_24920	COG1136	(ABC) transporter
WR51_24925	COG3708	Transcriptional regulator
WR51_24925	COG2207	Transcriptional regulator
WR51_24935	COG5658	integral membrane protein
WR51_24940	COG0640	Transcriptional regulator
WR51_24945	COG0745	RESPONSE REGULATOR receiver
WR51_24950	COG2205	protein histidine kinase activity
WR51_24955	COG0577	efflux transmembrane transporter activity
WR51_24960	COG0577	efflux transmembrane transporter activity
WR51_24965	COG1136	(ABC) transporter
WR51_24970	COG0577	efflux transmembrane transporter activity
WR51_25015	COG3964	amidohydrolase
WR51_25035	COG4948	Mandelate Racemase Muconate Lactonizing
WR51_25045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WR51_25050	COG0596	Alpha beta hydrolase
WR51_25060	COG1169	isochorismate synthase
WR51_25065	COG1575	Belongs to the MenA family. Type 1 subfamily
WR51_25070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WR51_25075	COG1278	Cold shock
WR51_25105	COG0058	SHG alpha-glucan phosphorylase activity
WR51_25115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WR51_25135	COG1404	Belongs to the peptidase S8 family
WR51_25270	COG1285	pathogenesis
WR51_25275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR51_25295	COG2155	Conserved Protein
WR51_25300	COG1098	S1 RNA binding domain
WR51_25305	COG0436	Aminotransferase
WR51_25310	COG1522	sequence-specific DNA binding
WR51_25315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR51_25320	COG2267	carboxylic ester hydrolase activity
WR51_25330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WR51_25350	COG5018	Exonuclease
WR51_25355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_25370	COG0423	glycine-tRNA ligase activity
WR51_25375	COG2050	protein possibly involved in aromatic compounds catabolism
WR51_25385	COG1268	BioY protein
WR51_25395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR51_25400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WR51_25420	COG2076	Multidrug Resistance protein
WR51_25425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WR51_25435	COG3584	3D domain protein
WR51_25450	COG1252	NADH dehydrogenase
WR51_25460	COG3708	Transcriptional regulator
WR51_25475	COG1683	Conserved Protein
WR51_25500	COG0316	Belongs to the HesB IscA family
WR51_25515	COG1252	NADH dehydrogenase
WR51_25525	COG2274	protein secretion by the type I secretion system
WR51_25530	COG0390	transport system, permease component
WR51_25535	COG2824	Alkylphosphonate utilization operon protein PhnA
WR51_25560	COG4837	Protein of unknown function (DUF1462)
WR51_25565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WR51_25575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_25580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WR51_25600	COG1358	cellular component organization or biogenesis
WR51_25610	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_25615	COG0647	UMP catabolic process
WR51_25625	COG2445	Protein of unknown function DUF86
WR51_25630	COG1494	fructose-1,6-bisphosphatase
WR51_25655	COG4470	Protein conserved in bacteria
WR51_25665	COG0789	Transcriptional regulator
WR51_25670	COG4377	Putative membrane peptidase family (DUF2324)
WR51_25695	COG0739	heme binding
WR51_25705	COG3377	Domain of unknown function (DUF1805)
WR51_25710	COG0737	Belongs to the 5'-nucleotidase family
WR51_25715	COG0719	Fe-S assembly protein
WR51_25720	COG0822	iron-sulfur transferase activity
WR51_25725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WR51_25730	COG0719	Fe-S assembly protein
WR51_25735	COG0396	ATPase activity
WR51_25740	COG1464	Belongs to the NlpA lipoprotein family
WR51_25745	COG1464	Belongs to the NlpA lipoprotein family
WR51_25750	COG2011	ABC-type metal ion transport system permease component
WR51_25765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_25770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
WR51_25780	COG1393	Belongs to the ArsC family
WR51_25815	COG0039	L-malate dehydrogenase activity
WR51_25835	COG1309	transcriptional regulator
WR51_25840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_25845	COG1960	acyl-CoA dehydrogenase activity
WR51_25850	COG0183	Belongs to the thiolase family
WR51_25855	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR51_25855	COG1024	Enoyl-CoA hydratase
WR51_25865	COG1686	Belongs to the peptidase S11 family
WR51_25880	COG0011	TIGRFAM Protein of
WR51_25885	COG0840	transmembrane signaling receptor activity
WR51_25900	COG2814	Major facilitator Superfamily
WR51_25905	COG0531	amino acid
WR51_25930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_25965	COG0586	Pfam SNARE associated Golgi protein
WR51_25975	COG1376	ErfK ybiS ycfS ynhG family protein
WR51_25980	COG0745	RESPONSE REGULATOR receiver
WR51_25985	COG5002	protein histidine kinase activity
WR51_26015	COG0840	transmembrane signaling receptor activity
WR51_26020	COG2151	metal-sulfur cluster biosynthetic enzyme
WR51_26025	COG3227	Zinc metalloprotease (Elastase)
WR51_26045	COG0586	Pfam SNARE associated Golgi protein
WR51_26050	COG0475	glutathione-regulated potassium exporter activity
WR51_26055	COG0490	domain, Protein
WR51_26065	COG1115	amino acid carrier protein
WR51_26070	COG0783	Belongs to the Dps family
WR51_26080	COG2318	DinB family
WR51_26090	COG1611	Belongs to the LOG family
WR51_26100	COG1528	Iron-storage protein
WR51_26110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_26120	COG1115	amino acid carrier protein
WR51_26125	COG1115	amino acid carrier protein
WR51_26130	COG2910	NAD(P)H-binding
WR51_26145	COG0656	L-ascorbic acid biosynthetic process
WR51_26150	COG2814	Major facilitator Superfamily
WR51_26155	COG1733	regulation of RNA biosynthetic process
WR51_26165	COG1252	NADH dehydrogenase
WR51_26170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WR51_26215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_26220	COG3223	Belongs to the PsiE family
WR51_26230	COG1335	isochorismatase
WR51_26235	COG1522	sequence-specific DNA binding
WR51_26245	COG1522	sequence-specific DNA binding
WR51_26250	COG0288	reversible hydration of carbon dioxide
WR51_26255	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
WR51_26260	COG2233	PERMEase
WR51_26305	COG0557	exoribonuclease II activity
WR51_26310	COG1647	Serine aminopeptidase, S33
WR51_26315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR51_26320	COG1346	cytolysis
WR51_26355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR51_26370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WR51_26380	COG1668	transmembrane transport
WR51_26385	COG4152	abc transporter atp-binding protein
WR51_26390	COG4585	Histidine kinase
WR51_26455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_26470	COG2323	membrane
WR51_26480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_26490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WR51_26500	COG1051	belongs to the nudix hydrolase family
WR51_26510	COG0492	ferredoxin-NADP+ reductase activity
WR51_26515	COG0457	Tetratricopeptide repeat
WR51_26520	COG0110	maltose O-acetyltransferase activity
WR51_26540	COG1950	PFAM Membrane protein of
WR51_26545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR51_26565	COG0789	Transcriptional regulator
WR51_26585	COG0583	DNA-binding transcription factor activity
WR51_26595	COG0655	NAD(P)H dehydrogenase (quinone) activity
WR51_26600	COG0488	(ABC) transporter
WR51_26610	COG1132	(ABC) transporter
WR51_26615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_26620	COG3409	Peptidoglycan-binding domain 1 protein
WR51_26620	COG0793	Belongs to the peptidase S41A family
WR51_26625	COG2177	Part of the ABC transporter FtsEX involved in
WR51_26630	COG2884	Cell division ATP-binding protein ftsE
WR51_26645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WR51_26660	COG1131	(ABC) transporter
WR51_26690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WR51_26695	COG1278	Cold shock
WR51_26700	COG1040	competence protein
WR51_26705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
WR51_26710	COG1388	LysM domain
WR51_26710	COG0791	NLP P60 protein
WR51_26715	COG1733	regulation of RNA biosynthetic process
WR51_26720	COG1307	EDD domain protein, DegV family
WR51_26725	COG1739	Uncharacterized protein family UPF0029
WR51_26730	COG1316	TRANSCRIPTIONal
WR51_26735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WR51_26740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR51_26745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WR51_26755	COG3933	PFAM sigma-54 factor interaction domain-containing protein
WR51_26755	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WR51_26775	COG1486	melibiose metabolic process
WR51_26780	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_26785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_26795	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WR51_26805	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_26815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_26820	COG1301	dicarboxylic acid transport
WR51_26835	COG1511	domain protein
WR51_26840	COG0583	DNA-binding transcription factor activity
WR51_26845	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WR51_26855	COG1271	oxidase subunit
WR51_26860	COG1294	oxidase, subunit
WR51_26865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_26875	COG1620	l-lactate permease
WR51_26885	COG2389	metal-binding protein
WR51_26895	COG1368	sulfuric ester hydrolase activity
WR51_26905	COG0791	NLP P60 protein
WR51_26905	COG1388	LysM domain
WR51_26910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_26920	COG1215	transferase activity, transferring glycosyl groups
WR51_26930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_26935	COG3584	3D domain protein
WR51_26935	COG1388	LysM domain
WR51_26960	COG4715	Zinc finger, swim domain protein
WR51_26965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_26995	COG1191	sigma factor activity
WR51_27005	COG0577	efflux transmembrane transporter activity
WR51_27010	COG1136	(ABC) transporter
WR51_27035	COG5002	protein histidine kinase activity
WR51_27040	COG0745	RESPONSE REGULATOR receiver
WR51_27045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_27050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_27070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR51_27085	COG0438	transferase activity, transferring glycosyl groups
WR51_27090	COG1215	transferase activity, transferring glycosyl groups
WR51_27095	COG0438	transferase activity, transferring glycosyl groups
WR51_27110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR51_27115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR51_27120	COG1086	Polysaccharide biosynthesis protein
WR51_27125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR51_27130	COG4464	protein tyrosine phosphatase activity
WR51_27135	COG0489	protein tyrosine kinase activity
WR51_27140	COG3944	biosynthesis protein
WR51_27145	COG0489	protein tyrosine kinase activity
WR51_27160	COG1609	Transcriptional regulator
WR51_27170	COG0739	heme binding
WR51_27185	COG3279	Response regulator of the LytR AlgR family
WR51_27190	COG2385	sporulation resulting in formation of a cellular spore
WR51_27195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WR51_27205	COG4836	Membrane
WR51_27210	COG1007	ATP synthesis coupled electron transport
WR51_27215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR51_27220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR51_27230	COG0839	Belongs to the complex I subunit 6 family
WR51_27250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR51_27265	COG5001	Diguanylate cyclase
WR51_27265	COG3300	MHYT domain
WR51_27315	COG0356	it plays a direct role in the translocation of protons across the membrane
WR51_27350	COG0698	ribose 5-phosphate isomerase
WR51_27360	COG2190	(PTS) system
WR51_27365	COG2259	Doxx family
WR51_27370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR51_27390	COG0009	L-threonylcarbamoyladenylate synthase
WR51_27410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WR51_27425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WR51_27430	COG1494	fructose-1,6-bisphosphatase
WR51_27450	COG4821	SIS domain
WR51_27460	COG3343	RNA polymerase activity
WR51_27470	COG1960	acyl-CoA dehydrogenase activity
WR51_27475	COG1960	acyl-CoA dehydrogenase activity
WR51_27480	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR51_27485	COG0183	Belongs to the thiolase family
WR51_27490	COG2181	nitrate reductase activity
WR51_27490	COG0247	lactate metabolic process
WR51_27495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_27505	COG5001	Diguanylate cyclase
WR51_27505	COG3300	MHYT domain
WR51_27520	COG3227	Zinc metalloprotease (Elastase)
WR51_27525	COG2197	response regulator
WR51_27530	COG4585	Histidine kinase
WR51_27535	COG0842	Transport permease protein
WR51_27540	COG1131	(ABC) transporter
WR51_27545	COG0024	Methionine aminopeptidase
WR51_27555	COG2234	aminopeptidase activity
WR51_27575	COG1595	DNA-templated transcription, initiation
WR51_27585	COG4506	Protein conserved in bacteria
WR51_27590	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_27615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WR51_27620	COG2814	Major facilitator Superfamily
WR51_27625	COG0789	Transcriptional regulator
WR51_27630	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_27635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_27645	COG1994	Peptidase M50
WR51_27655	COG1078	dGTPase activity
WR51_27660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_27665	COG1120	ATPase activity
WR51_27670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_27675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_27695	COG0280	phosphate acetyltransferase
WR51_27710	COG3773	Cell wall hydrolase
WR51_27720	COG2363	Small membrane protein
WR51_27730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR51_27735	COG2233	PERMEase
WR51_27740	COG0561	phosphatase activity
WR51_27745	COG2814	Major facilitator Superfamily
WR51_27755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR51_27760	COG1131	(ABC) transporter
WR51_27765	COG2755	lipolytic protein G-D-S-L family
WR51_27770	COG1609	Transcriptional regulator
WR51_27780	COG0460	homoserine dehydrogenase
WR51_27800	COG1011	Hydrolase
WR51_27805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_27815	COG2197	response regulator
WR51_27820	COG2203	Gaf domain
WR51_27820	COG4585	Histidine kinase
WR51_27825	COG0351	phosphomethylpyrimidine kinase
WR51_27830	COG3706	GGDEF domain
WR51_27835	COG2879	small protein
WR51_27840	COG1966	Carbon starvation protein
WR51_27845	COG3279	Response regulator of the LytR AlgR family
WR51_27850	COG0477	Major facilitator Superfamily
WR51_27860	COG0438	transferase activity, transferring glycosyl groups
WR51_27875	COG0840	transmembrane signaling receptor activity
WR51_27885	COG1607	acyl-coa hydrolase
WR51_27890	COG1216	Glycosyl transferase, family 2
WR51_27900	COG1216	Glycosyl transferase, family 2
WR51_27910	COG4485	Bacterial membrane protein, YfhO
WR51_27915	COG0463	Glycosyl transferase, family 2
WR51_27925	COG1309	transcriptional regulator
WR51_27930	COG0488	(ABC) transporter
WR51_27935	COG1309	transcriptional regulator
WR51_27940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR51_27945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_27945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_27950	COG0628	permease
WR51_27970	COG3275	phosphorelay sensor kinase activity
WR51_27975	COG2814	Major facilitator Superfamily
WR51_27980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_27985	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
WR51_28010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_28015	COG1272	protein, Hemolysin III
WR51_28035	COG1164	Oligoendopeptidase f
WR51_28045	COG5002	protein histidine kinase activity
WR51_28060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_28065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WR51_28070	COG4853	Protein conserved in bacteria
WR51_28080	COG5002	protein histidine kinase activity
WR51_28085	COG0745	RESPONSE REGULATOR receiver
WR51_28115	COG0305	Participates in initiation and elongation during chromosome replication
WR51_28125	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
WR51_28130	COG4241	membrane
WR51_28140	COG0629	single-stranded DNA binding
WR51_28150	COG0012	GTP binding
WR51_28155	COG4481	Protein conserved in bacteria
WR51_28160	COG0668	transmembrane transport
WR51_28170	COG1475	DNA binding
WR51_28175	COG1192	Involved in chromosome partitioning
WR51_28200	COG1847	R3H domain protein
WR51_28230	COG1404	Belongs to the peptidase S8 family
WR51_28245	COG5549	protein import
WR51_28245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_28280	COG2259	Doxx family
WR51_28285	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_28310	COG2814	Major facilitator Superfamily
WR51_28340	COG4641	Protein conserved in bacteria
WR51_28355	COG2089	acid synthase
WR51_28370	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WR51_28375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR51_28380	COG1088	dTDP-glucose 4,6-dehydratase activity
WR51_28385	COG1086	Polysaccharide biosynthesis protein
WR51_28390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WR51_28395	COG0463	Glycosyl transferase, family 2
WR51_28400	COG0463	Glycosyl transferase, family 2
WR51_28410	COG0457	Tetratricopeptide repeat
WR51_28440	COG0494	nUDIX hydrolase
WR51_28450	COG4974	Belongs to the 'phage' integrase family
WR51_28485	COG0457	Tetratricopeptide repeat
WR51_28490	COG1923	regulation of RNA biosynthetic process
WR51_28495	COG2318	DinB family
WR51_28645	COG1475	DNA binding
WR51_28665	COG0738	Major facilitator superfamily
WR51_28670	COG0673	inositol 2-dehydrogenase activity
WR51_28675	COG0561	phosphatase activity
WR51_28680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR51_28685	COG1609	Transcriptional regulator
WR51_28720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_28725	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_28725	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_28725	COG3321	synthase
WR51_28725	COG0300	oxidoreductase activity
WR51_28725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_28740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_28745	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR51_28760	COG1960	acyl-CoA dehydrogenase activity
WR51_28780	COG3321	synthase
WR51_28780	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_28780	COG0300	oxidoreductase activity
WR51_28780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_28780	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_28780	COG3321	synthase
WR51_28780	COG0300	oxidoreductase activity
WR51_28780	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_28780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_28780	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_28805	COG0667	Aldo Keto reductase
WR51_28820	COG3391	amine dehydrogenase activity
WR51_28835	COG1396	sequence-specific DNA binding
WR51_28865	COG0210	DNA helicase
WR51_28870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WR51_28880	COG1204	response to ionizing radiation
WR51_28940	COG0210	DNA helicase
WR51_28975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR51_28985	COG0457	Tetratricopeptide repeat
WR51_28995	COG1846	Transcriptional regulator
WR51_28995	COG0456	acetyltransferase
WR51_29035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR51_29040	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_29040	COG3409	Peptidoglycan-binding domain 1 protein
WR51_29080	COG0367	asparagine synthase
WR51_29085	COG1309	transcriptional regulator
WR51_29105	COG0726	polysaccharide deacetylase
WR51_29115	COG1396	sequence-specific DNA binding
WR51_29140	COG2274	protein secretion by the type I secretion system
WR51_29215	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_29230	COG3409	Peptidoglycan-binding domain 1 protein
WR51_29230	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_29230	COG1388	LysM domain
WR51_29235	COG0739	heme binding
WR51_29240	COG0741	lytic transglycosylase activity
WR51_29270	COG5634	Uncharacterized conserved protein (DUF2278)
WR51_29275	COG2234	aminopeptidase activity
WR51_29315	COG0463	Glycosyl transferase, family 2
WR51_29350	COG0542	response to heat
WR51_29355	COG0494	nUDIX hydrolase
WR51_29390	COG0457	Tetratricopeptide repeat
WR51_29765	COG2211	Major facilitator Superfamily
WR51_29785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_29895	COG2311	Membrane
WR51_29905	COG0823	Involved in the tonB-independent uptake of proteins
WR51_29945	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
WR51_29950	COG0583	DNA-binding transcription factor activity
WR51_29970	COG0577	efflux transmembrane transporter activity
WR51_29975	COG1136	(ABC) transporter
WR51_29980	COG2205	protein histidine kinase activity
WR51_29985	COG0745	RESPONSE REGULATOR receiver
WR51_30015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR51_30040	COG1819	glycosyl
WR51_30055	COG2801	Transposase and inactivated derivatives
WR51_30090	COG0776	regulation of translation
WR51_30095	COG2002	toxin-antitoxin pair type II binding
WR51_30125	COG0697	spore germination
WR51_30130	COG1802	Transcriptional regulator
WR51_30135	COG0697	spore germination
WR51_30145	COG2211	Major facilitator Superfamily
WR51_30150	COG2366	antibiotic biosynthetic process
WR51_30190	COG2423	ornithine cyclodeaminase activity
WR51_30205	COG0776	regulation of translation
WR51_30215	COG2002	toxin-antitoxin pair type II binding
WR51_30220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_30225	COG0438	transferase activity, transferring glycosyl groups
WR51_30230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_30245	COG0438	transferase activity, transferring glycosyl groups
WR51_30250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_30255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR51_30260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR51_30265	COG3104	oligopeptide transport
WR51_30275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_30285	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_30305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_30415	COG5634	Uncharacterized conserved protein (DUF2278)
WR51_30425	COG1404	Belongs to the peptidase S8 family
WR51_30460	COG2304	oxidoreductase activity
WR51_30465	COG1309	transcriptional regulator
WR51_30470	COG2814	Major facilitator Superfamily
WR51_30475	COG1760	l-serine dehydratase
WR51_30480	COG1760	l-serine dehydratase
WR51_30485	COG0814	amino acid
WR51_30500	COG0840	transmembrane signaling receptor activity
WR51_30520	COG1309	transcriptional regulator
WR51_30530	COG0456	acetyltransferase
WR51_30540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR51_30545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_30550	COG0772	Belongs to the SEDS family
WR51_30555	COG2239	Acts as a magnesium transporter
WR51_30620	COG4974	Belongs to the 'phage' integrase family