locus-tag	class	description
WR47_00010	COG0592	DNA-directed DNA polymerase activity
WR47_00015	COG2501	S4 domain
WR47_00025	COG0187	DNA topoisomerase II activity
WR47_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR47_00065	COG0516	GMP reductase activity
WR47_00065	COG0517	IMP dehydrogenase activity
WR47_00070	COG1686	Belongs to the peptidase S11 family
WR47_00100	COG1428	Deoxynucleoside kinase
WR47_00105	COG1428	Deoxynucleoside kinase
WR47_00110	COG1335	isochorismatase
WR47_00120	COG0590	tRNA wobble adenosine to inosine editing
WR47_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WR47_00180	COG1982	Orn Lys Arg decarboxylase major
WR47_00190	COG0470	DNA polymerase III
WR47_00195	COG1774	PSP1 C-terminal conserved region
WR47_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WR47_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WR47_00220	COG2002	toxin-antitoxin pair type II binding
WR47_00230	COG0084	hydrolase, TatD family'
WR47_00250	COG4466	Protein conserved in bacteria
WR47_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WR47_00270	COG0251	oxidation-reduction process
WR47_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WR47_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WR47_00305	COG2002	toxin-antitoxin pair type II binding
WR47_00310	COG2244	polysaccharide biosynthetic process
WR47_00315	COG3956	TIGRFAM MazG family protein
WR47_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WR47_00340	COG1098	S1 RNA binding domain
WR47_00355	COG2208	phosphoserine phosphatase activity
WR47_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WR47_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR47_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WR47_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
WR47_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR47_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WR47_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WR47_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WR47_00420	COG1396	sequence-specific DNA binding
WR47_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR47_00515	COG3880	PFAM UvrB UvrC protein
WR47_00525	COG0542	response to heat
WR47_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WR47_00540	COG4956	integral membrane protein (PIN domain superfamily)
WR47_00560	COG1045	serine acetyltransferase
WR47_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR47_00580	COG3688	RNA-binding protein containing a PIN domain
WR47_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WR47_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR47_00600	COG0250	Participates in transcription elongation, termination and antitermination
WR47_00625	COG2813	Specifically methylates the guanine in position
WR47_00640	COG1358	cellular component organization or biogenesis
WR47_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WR47_00770	COG0201	protein transport
WR47_00780	COG0024	Methionine aminopeptidase
WR47_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WR47_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR47_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR47_00855	COG0489	protein tyrosine kinase activity
WR47_00865	COG2194	sulfuric ester hydrolase activity
WR47_00870	COG0726	polysaccharide deacetylase
WR47_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
WR47_00955	COG4856	YbbR-like protein
WR47_00995	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_01000	COG2011	ABC-type metal ion transport system permease component
WR47_01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WR47_01010	COG1464	Belongs to the NlpA lipoprotein family
WR47_01015	COG0604	alcohol dehydrogenase
WR47_01025	COG0277	FAD linked oxidase domain protein
WR47_01030	COG2271	Major facilitator Superfamily
WR47_01040	COG2814	Major facilitator Superfamily
WR47_01060	COG0601	transmembrane transport
WR47_01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR47_01070	COG0444	Belongs to the ABC transporter superfamily
WR47_01075	COG4608	Belongs to the ABC transporter superfamily
WR47_01080	COG4166	transmembrane transport
WR47_01095	COG4166	transmembrane transport
WR47_01100	COG4166	transmembrane transport
WR47_01105	COG0656	L-ascorbic acid biosynthetic process
WR47_01130	COG4149	molybdate abc transporter
WR47_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
WR47_01140	COG1910	domain protein
WR47_01160	COG0697	spore germination
WR47_01175	COG0204	Acyl-transferase
WR47_01185	COG1609	Transcriptional regulator
WR47_01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_01215	COG5298	Protein conserved in bacteria
WR47_01240	COG0488	(ABC) transporter
WR47_01250	COG0747	negative chemotaxis
WR47_01255	COG0601	transmembrane transport
WR47_01265	COG0444	Belongs to the ABC transporter superfamily
WR47_01270	COG4608	Belongs to the ABC transporter superfamily
WR47_01275	COG0561	phosphatase activity
WR47_01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
WR47_01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR47_01320	COG0531	amino acid
WR47_01325	COG2814	Major facilitator Superfamily
WR47_01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR47_01345	COG4294	response to UV
WR47_01350	COG0705	Rhomboid family
WR47_01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WR47_01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR47_01370	COG0864	Transcriptional regulator
WR47_01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
WR47_01380	COG2183	response to ionizing radiation
WR47_01480	COG0802	atpase or kinase
WR47_01485	COG1214	PFAM Peptidase M22, glycoprotease
WR47_01490	COG0456	acetyltransferase
WR47_01500	COG0488	(ABC) transporter
WR47_01515	COG1266	CAAX protease self-immunity
WR47_01545	COG2252	PERMEase
WR47_01555	COG5002	protein histidine kinase activity
WR47_01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR47_01630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR47_01650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_01655	COG0506	proline dehydrogenase activity
WR47_01700	COG2205	protein histidine kinase activity
WR47_01705	COG0745	RESPONSE REGULATOR receiver
WR47_01725	COG0697	spore germination
WR47_01755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WR47_01760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WR47_01765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WR47_01775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WR47_01790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WR47_01800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WR47_01810	COG0151	Belongs to the GarS family
WR47_01820	COG0583	DNA-binding transcription factor activity
WR47_01845	COG0210	DNA helicase
WR47_01855	COG4851	CamS sex pheromone cAM373 precursor
WR47_01870	COG1335	isochorismatase
WR47_01885	COG2011	ABC-type metal ion transport system permease component
WR47_01890	COG1464	Belongs to the NlpA lipoprotein family
WR47_01905	COG0003	Pfam Anion-transporting ATPase
WR47_01910	COG1846	Transcriptional regulator
WR47_01915	COG4682	membrane
WR47_01935	COG1597	lipid kinase activity
WR47_01945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WR47_01955	COG1012	belongs to the aldehyde dehydrogenase family
WR47_01960	COG2076	Multidrug Resistance protein
WR47_01965	COG2309	aminopeptidase activity
WR47_01980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_01990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR47_01995	COG4807	Protein conserved in bacteria
WR47_02025	COG1473	amidohydrolase
WR47_02045	COG0450	alkyl hydroperoxide reductase
WR47_02050	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
WR47_02060	COG0235	Class ii aldolase
WR47_02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_02075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_02100	COG0166	Belongs to the GPI family
WR47_02125	COG5002	protein histidine kinase activity
WR47_02145	COG3541	Predicted nucleotidyltransferase
WR47_02150	COG2814	Major facilitator Superfamily
WR47_02155	COG0723	plastoquinol--plastocyanin reductase activity
WR47_02155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR47_02165	COG0765	amino acid transport
WR47_02170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR47_02180	COG0840	transmembrane signaling receptor activity
WR47_02205	COG0549	Belongs to the carbamate kinase family
WR47_02210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR47_02220	COG0277	FAD linked oxidase domain protein
WR47_02225	COG0366	Alpha amylase catalytic
WR47_02230	COG1263	PTS System
WR47_02230	COG2190	(PTS) system
WR47_02230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR47_02260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WR47_02280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR47_02285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR47_02290	COG1116	anion transmembrane transporter activity
WR47_02295	COG0488	(ABC) transporter
WR47_02340	COG2270	Major facilitator Superfamily
WR47_02370	COG2310	stress, protein
WR47_02375	COG2310	stress, protein
WR47_02380	COG2310	stress, protein
WR47_02385	COG0861	Integral membrane protein TerC family
WR47_02395	COG3853	Toxic anion resistance protein (TelA)
WR47_02410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WR47_02420	COG1295	ribonuclease BN
WR47_02425	COG2217	Heavy metal translocating P-type atpase
WR47_02430	COG0697	spore germination
WR47_02450	COG0586	Pfam SNARE associated Golgi protein
WR47_02465	COG3871	stress protein (general stress protein 26)
WR47_02470	COG0387	Pfam Sodium calcium exchanger
WR47_02480	COG0535	radical SAM domain protein
WR47_02500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR47_02505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WR47_02520	COG3829	transcription factor binding
WR47_02530	COG0833	amino acid
WR47_02535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR47_02565	COG1263	PTS System
WR47_02565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR47_02570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_02585	COG1216	Glycosyl transferase, family 2
WR47_02595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WR47_02595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR47_02600	COG0463	Glycosyl transferase, family 2
WR47_02615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WR47_02635	COG1228	amidohydrolase
WR47_02640	COG1090	epimerase
WR47_02670	COG1988	membrane-bound metal-dependent
WR47_02675	COG1194	a g-specific adenine glycosylase
WR47_02700	COG1132	(ABC) transporter
WR47_02705	COG4129	membrane
WR47_02710	COG0070	glutamate synthase
WR47_02710	COG0067	glutamate synthase
WR47_02710	COG0069	glutamate synthase activity
WR47_02720	COG4555	ABC transporter
WR47_02740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WR47_02745	COG0735	belongs to the Fur family
WR47_02865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WR47_02890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WR47_02895	COG5001	Diguanylate cyclase
WR47_02895	COG1716	ATPase activity
WR47_02905	COG2766	serine protein kinase
WR47_02950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR47_02950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR47_02950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR47_02950	COG3321	synthase
WR47_02950	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_02980	COG2801	Transposase and inactivated derivatives
WR47_03005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR47_03015	COG1585	Membrane protein implicated in regulation of membrane protease activity
WR47_03020	COG2268	Band 7 protein
WR47_03030	COG3290	protein histidine kinase activity
WR47_03035	COG4565	transcriptional regulatory protein
WR47_03040	COG2851	Citrate transporter
WR47_03065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR47_03070	COG3842	ATPase activity
WR47_03075	COG1175	transmembrane transport
WR47_03080	COG0395	ABC-type sugar transport system, permease component
WR47_03090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WR47_03095	COG0745	RESPONSE REGULATOR receiver
WR47_03100	COG5002	protein histidine kinase activity
WR47_03110	COG4990	cell redox homeostasis
WR47_03120	COG3290	protein histidine kinase activity
WR47_03125	COG4565	transcriptional regulatory protein
WR47_03130	COG3493	citrate carrier protein
WR47_03135	COG0281	malic enzyme
WR47_03145	COG0697	spore germination
WR47_03150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_03160	COG5002	protein histidine kinase activity
WR47_03165	COG0745	RESPONSE REGULATOR receiver
WR47_03175	COG0454	-acetyltransferase
WR47_03175	COG0456	acetyltransferase
WR47_03180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR47_03185	COG3383	formate dehydrogenase (NAD+) activity
WR47_03190	COG2427	Protein of unknown function (DUF1641)
WR47_03205	COG0531	amino acid
WR47_03215	COG0640	Transcriptional regulator
WR47_03220	COG2217	Heavy metal translocating P-type atpase
WR47_03225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WR47_03235	COG3227	Zinc metalloprotease (Elastase)
WR47_03255	COG2720	vancomycin resistance protein
WR47_03260	COG1316	TRANSCRIPTIONal
WR47_03265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_03270	COG0346	lactoylglutathione lyase activity
WR47_03275	COG1253	flavin adenine dinucleotide binding
WR47_03280	COG1027	Aspartate ammonia-lyase
WR47_03285	COG1620	l-lactate permease
WR47_03300	COG3104	oligopeptide transport
WR47_03305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_03330	COG0156	8-amino-7-oxononanoate synthase activity
WR47_03335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR47_03340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WR47_03350	COG4548	von Willebrand factor, type A
WR47_03355	COG0714	Associated with various cellular activities
WR47_03375	COG0531	amino acid
WR47_03380	COG2188	Transcriptional regulator
WR47_03385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR47_03385	COG1263	PTS System
WR47_03390	COG0366	Alpha amylase catalytic
WR47_03405	COG0697	spore germination
WR47_03415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR47_03420	COG1115	amino acid carrier protein
WR47_03425	COG1126	abc transporter atp-binding protein
WR47_03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR47_03435	COG0765	amino acid transport
WR47_03440	COG0765	amino acid transport
WR47_03445	COG0833	amino acid
WR47_03460	COG1595	DNA-templated transcription, initiation
WR47_03470	COG2378	regulation of single-species biofilm formation
WR47_03475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WR47_03480	COG5002	protein histidine kinase activity
WR47_03505	COG0659	secondary active sulfate transmembrane transporter activity
WR47_03520	COG0747	negative chemotaxis
WR47_03530	COG0601	transmembrane transport
WR47_03535	COG4608	Belongs to the ABC transporter superfamily
WR47_03545	COG2271	Major facilitator Superfamily
WR47_03550	COG1846	Transcriptional regulator
WR47_03555	COG0477	Major facilitator Superfamily
WR47_03560	COG1609	Transcriptional regulator
WR47_03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WR47_03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR47_03585	COG1879	ABC-type sugar transport system periplasmic component
WR47_03590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WR47_03610	COG1063	alcohol dehydrogenase
WR47_03660	COG0840	transmembrane signaling receptor activity
WR47_03665	COG3584	3D domain protein
WR47_03665	COG3583	domain protein
WR47_03670	COG1476	TRANSCRIPTIONal
WR47_03690	COG3104	oligopeptide transport
WR47_03695	COG1114	Component of the transport system for branched-chain amino acids
WR47_03710	COG1113	amino acid transport
WR47_03715	COG2252	PERMEase
WR47_03730	COG2153	protein acetylation
WR47_03740	COG0475	glutathione-regulated potassium exporter activity
WR47_03740	COG0569	domain protein
WR47_03750	COG1845	cytochrome c oxidase, subunit III
WR47_03755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WR47_03765	COG0833	amino acid
WR47_03770	COG4990	cell redox homeostasis
WR47_03785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR47_03790	COG0697	spore germination
WR47_03795	COG0531	amino acid
WR47_03810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR47_03815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR47_03820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR47_03820	COG1918	ferrous iron import across plasma membrane
WR47_03825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR47_03830	COG0573	inorganic phosphate transmembrane transporter activity
WR47_03835	COG0581	inorganic phosphate transmembrane transporter activity
WR47_03845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR47_03965	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
WR47_03990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR47_03995	COG1116	anion transmembrane transporter activity
WR47_04000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR47_04005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR47_04010	COG0352	thiamine-phosphate diphosphorylase activity
WR47_04015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR47_04020	COG2104	thiamine diphosphate biosynthetic process
WR47_04030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR47_04035	COG0351	phosphomethylpyrimidine kinase
WR47_04075	COG2205	protein histidine kinase activity
WR47_04080	COG2814	Major facilitator Superfamily
WR47_04085	COG1846	Transcriptional regulator
WR47_04100	COG2801	Transposase and inactivated derivatives
WR47_04110	COG2252	PERMEase
WR47_04115	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_04175	COG0778	Nitroreductase
WR47_04180	COG2719	SpoVR family
WR47_04190	COG1414	Transcriptional regulator
WR47_04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
WR47_04210	COG1937	Protein conserved in bacteria
WR47_04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_04215	COG0425	Belongs to the sulfur carrier protein TusA family
WR47_04220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_04225	COG0425	Belongs to the sulfur carrier protein TusA family
WR47_04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_04240	COG2210	Belongs to the sulfur carrier protein TusA family
WR47_04245	COG0730	response to heat
WR47_04255	COG1316	TRANSCRIPTIONal
WR47_04260	COG0604	alcohol dehydrogenase
WR47_04265	COG1283	sodium-dependent phosphate transmembrane transporter activity
WR47_04280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR47_04280	COG3711	transcriptional antiterminator
WR47_04285	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR47_04290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR47_04310	COG1388	LysM domain
WR47_04310	COG3584	3D domain protein
WR47_04315	COG0577	efflux transmembrane transporter activity
WR47_04320	COG1136	(ABC) transporter
WR47_04330	COG5522	Integral membrane protein (intg_mem_TP0381)
WR47_04345	COG1114	Component of the transport system for branched-chain amino acids
WR47_04350	COG3546	catalase activity
WR47_04385	COG0586	Pfam SNARE associated Golgi protein
WR47_04420	COG0531	amino acid
WR47_04425	COG0475	glutathione-regulated potassium exporter activity
WR47_04435	COG1737	Transcriptional regulator
WR47_04445	COG1263	PTS System
WR47_04445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR47_04455	COG2259	Doxx family
WR47_04475	COG1522	sequence-specific DNA binding
WR47_04480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WR47_04480	COG0165	Argininosuccinate lyase
WR47_04485	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_04495	COG2076	Multidrug Resistance protein
WR47_04505	COG1309	transcriptional regulator
WR47_04510	COG2814	Major facilitator Superfamily
WR47_04515	COG1733	regulation of RNA biosynthetic process
WR47_04535	COG0693	protein deglycase activity
WR47_04550	COG0531	amino acid
WR47_04565	COG1012	belongs to the aldehyde dehydrogenase family
WR47_04575	COG1132	(ABC) transporter
WR47_04580	COG1132	(ABC) transporter
WR47_04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR47_04590	COG0765	amino acid transport
WR47_04595	COG1126	abc transporter atp-binding protein
WR47_04610	COG0189	ligase activity
WR47_04630	COG4585	Histidine kinase
WR47_04635	COG2197	response regulator
WR47_04655	COG0028	Belongs to the TPP enzyme family
WR47_04660	COG3527	Alpha-acetolactate decarboxylase
WR47_04670	COG0561	phosphatase activity
WR47_04680	COG3409	Peptidoglycan-binding domain 1 protein
WR47_04680	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_04685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR47_04690	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_04705	COG0659	secondary active sulfate transmembrane transporter activity
WR47_04710	COG2244	polysaccharide biosynthetic process
WR47_04730	COG1024	Enoyl-CoA hydratase
WR47_04750	COG1363	Peptidase, m42
WR47_04790	COG0601	transmembrane transport
WR47_04795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR47_04800	COG0444	Belongs to the ABC transporter superfamily
WR47_04805	COG4608	Belongs to the ABC transporter superfamily
WR47_04845	COG0477	Major facilitator Superfamily
WR47_04850	COG3290	protein histidine kinase activity
WR47_04855	COG4565	transcriptional regulatory protein
WR47_04860	COG3181	Tripartite tricarboxylate transporter family receptor
WR47_04925	COG0305	Participates in initiation and elongation during chromosome replication
WR47_04965	COG0477	Major facilitator Superfamily
WR47_04975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_04990	COG5504	Zn-dependent protease
WR47_04995	COG0789	Transcriptional regulator
WR47_05030	COG1329	Transcriptional regulator
WR47_05045	COG1278	Cold shock
WR47_05060	COG1131	(ABC) transporter
WR47_05090	COG2373	Large extracellular alpha-helical protein
WR47_05120	COG1073	alpha beta
WR47_05170	COG1183	phosphatidylcholine synthase activity
WR47_05185	COG2814	Major facilitator Superfamily
WR47_05190	COG0640	Transcriptional regulator
WR47_05200	COG2376	Dihydroxyacetone kinase
WR47_05210	COG2376	Dihydroxyacetone kinase
WR47_05245	COG0457	Tetratricopeptide repeat
WR47_05250	COG2373	Large extracellular alpha-helical protein
WR47_05290	COG3237	CsbD-like
WR47_05315	COG1191	sigma factor activity
WR47_05325	COG2208	phosphoserine phosphatase activity
WR47_05330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR47_05375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
WR47_05395	COG0420	3'-5' exonuclease activity
WR47_05400	COG4717	serine-type aminopeptidase activity
WR47_05420	COG1280	lysine exporter protein (LysE YggA)
WR47_05425	COG0346	lactoylglutathione lyase activity
WR47_05430	COG0346	lactoylglutathione lyase activity
WR47_05440	COG0457	Tetratricopeptide repeat
WR47_05450	COG2267	carboxylic ester hydrolase activity
WR47_05465	COG2140	Oxalate decarboxylase
WR47_05470	COG3620	sequence-specific DNA binding
WR47_05480	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR47_05485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WR47_05495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WR47_05505	COG1595	DNA-templated transcription, initiation
WR47_05515	COG0772	Belongs to the SEDS family
WR47_05520	COG3973	AAA domain
WR47_05550	COG4980	gas vesicle protein
WR47_05555	COG0537	adenosine 5'-monophosphoramidase activity
WR47_05560	COG1131	(ABC) transporter
WR47_05565	COG4473	ABC transporter
WR47_05615	COG1309	transcriptional regulator
WR47_05625	COG3402	PFAM membrane-flanked domain
WR47_05630	COG3428	Bacterial PH domain
WR47_05675	COG0697	spore germination
WR47_05680	COG3402	PFAM membrane-flanked domain
WR47_05685	COG3428	Bacterial PH domain
WR47_05690	COG2329	Antibiotic biosynthesis monooxygenase
WR47_05695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR47_05745	COG1309	transcriptional regulator
WR47_05750	COG1511	domain protein
WR47_05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_05775	COG1609	Transcriptional regulator
WR47_05785	COG1234	tRNA 3'-trailer cleavage
WR47_05790	COG0095	Lipoate-protein ligase
WR47_05800	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_05810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WR47_05820	COG4208	sulfate ABC transporter
WR47_05840	COG1408	metallophosphoesterase
WR47_05845	COG1078	dGTPase activity
WR47_05855	COG1595	DNA-templated transcription, initiation
WR47_05860	COG3708	Transcriptional regulator
WR47_05860	COG2207	Transcriptional regulator
WR47_05870	COG2205	protein histidine kinase activity
WR47_05875	COG0745	RESPONSE REGULATOR receiver
WR47_05895	COG0501	Belongs to the peptidase M48B family
WR47_05900	COG0840	transmembrane signaling receptor activity
WR47_05905	COG3693	PFAM glycoside hydrolase, family 10
WR47_05915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WR47_05920	COG2224	Isocitrate lyase
WR47_05935	COG1278	Cold shock
WR47_05955	COG0398	Pfam SNARE associated Golgi protein
WR47_05975	COG0202	RNA polymerase activity
WR47_06015	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR47_06040	COG0367	asparagine synthase
WR47_06050	COG0753	catalase activity
WR47_06055	COG0004	ammonium transporteR
WR47_06075	COG2996	Protein conserved in bacteria
WR47_06090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_06105	COG0561	phosphatase activity
WR47_06130	COG2267	carboxylic ester hydrolase activity
WR47_06145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR47_06150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WR47_06155	COG5504	Zn-dependent protease
WR47_06165	COG0180	Tryptophanyl-tRNA synthetase
WR47_06175	COG4166	transmembrane transport
WR47_06180	COG0601	transmembrane transport
WR47_06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR47_06190	COG0444	Belongs to the ABC transporter superfamily
WR47_06195	COG4608	Belongs to the ABC transporter superfamily
WR47_06200	COG0534	Mate efflux family protein
WR47_06205	COG4166	transmembrane transport
WR47_06220	COG1393	Belongs to the ArsC family
WR47_06225	COG0861	Integral membrane protein TerC family
WR47_06235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR47_06245	COG1164	Oligoendopeptidase f
WR47_06260	COG2346	COG2346, Truncated hemoglobins
WR47_06265	COG4116	CYTH
WR47_06275	COG2357	RelA SpoT domain protein
WR47_06285	COG0564	pseudouridine synthase activity
WR47_06300	COG0772	Belongs to the SEDS family
WR47_06305	COG1216	Glycosyl transferase, family 2
WR47_06325	COG0463	Glycosyl transferase, family 2
WR47_06325	COG0457	Tetratricopeptide repeat
WR47_06345	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WR47_06360	COG1091	dTDP-4-dehydrorhamnose reductase activity
WR47_06405	COG2153	protein acetylation
WR47_06415	COG2382	esterase
WR47_06445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR47_06460	COG0512	Glutamine amidotransferase of anthranilate synthase
WR47_06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WR47_06505	COG1620	l-lactate permease
WR47_06515	COG5634	Uncharacterized conserved protein (DUF2278)
WR47_06565	COG2226	methyltransferase
WR47_06585	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR47_06595	COG1476	TRANSCRIPTIONal
WR47_06660	COG2226	methyltransferase
WR47_06670	COG1686	Belongs to the peptidase S11 family
WR47_06675	COG0681	Belongs to the peptidase S26 family
WR47_06710	COG1012	belongs to the aldehyde dehydrogenase family
WR47_06720	COG1176	ABC-type spermidine putrescine transport system, permease component I
WR47_06725	COG1177	transmembrane transport
WR47_06730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WR47_06740	COG2409	Drug exporters of the RND superfamily
WR47_06750	COG0564	pseudouridine synthase activity
WR47_06760	COG2340	Cysteine-rich secretory protein family
WR47_06765	COG0247	lactate metabolic process
WR47_06770	COG0277	FAD linked oxidase domain protein
WR47_06775	COG3835	regulator
WR47_06785	COG0745	RESPONSE REGULATOR receiver
WR47_06790	COG5002	protein histidine kinase activity
WR47_06795	COG2186	Transcriptional regulator
WR47_06815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WR47_06825	COG2116	formate transmembrane transporter activity
WR47_06830	COG0861	Integral membrane protein TerC family
WR47_06835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR47_06845	COG2030	dehydratase
WR47_06865	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_06870	COG3243	poly(R)-hydroxyalkanoic acid synthase
WR47_06880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR47_06895	COG1840	ABC-type Fe3 transport system, periplasmic component
WR47_06900	COG3842	ATPase activity
WR47_06925	COG1349	DNA-binding transcription factor activity
WR47_06940	COG0235	Class ii aldolase
WR47_06950	COG2861	carbohydrate metabolic process
WR47_06960	COG3852	Histidine kinase
WR47_06965	COG1846	Transcriptional regulator
WR47_06975	COG2318	DinB family
WR47_06985	COG5002	protein histidine kinase activity
WR47_06995	COG0720	synthase
WR47_07010	COG4873	Protein conserved in bacteria
WR47_07050	COG1780	Probably involved in ribonucleotide reductase function
WR47_07055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR47_07060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR47_07065	COG1725	Transcriptional regulator
WR47_07070	COG1131	(ABC) transporter
WR47_07080	COG1131	(ABC) transporter
WR47_07100	COG1522	sequence-specific DNA binding
WR47_07110	COG1335	isochorismatase
WR47_07120	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR47_07125	COG2070	2-Nitropropane dioxygenase
WR47_07130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR47_07140	COG1696	Membrane protein involved in D-alanine export
WR47_07165	COG0716	FMN binding
WR47_07220	COG1846	Transcriptional regulator
WR47_07230	COG1301	dicarboxylic acid transport
WR47_07235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR47_07240	COG4709	membrane
WR47_07245	COG3874	Sporulation protein YtfJ
WR47_07275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR47_07280	COG0028	Belongs to the TPP enzyme family
WR47_07285	COG0440	acetolactate synthase activity
WR47_07360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR47_07375	COG1183	phosphatidylcholine synthase activity
WR47_07380	COG1368	sulfuric ester hydrolase activity
WR47_07390	COG0019	diaminopimelate decarboxylase activity
WR47_07410	COG0529	Catalyzes the synthesis of activated sulfate
WR47_07415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR47_07435	COG1648	precorrin-2 dehydrogenase activity
WR47_07445	COG0733	neurotransmitter:sodium symporter activity
WR47_07465	COG1757	Na H antiporter
WR47_07480	COG4758	membrane
WR47_07485	COG4585	Histidine kinase
WR47_07490	COG2197	response regulator
WR47_07500	COG1114	Component of the transport system for branched-chain amino acids
WR47_07510	COG2226	methyltransferase
WR47_07555	COG0730	response to heat
WR47_07560	COG0306	phosphate transporter
WR47_07565	COG1392	Phosphate transport regulator
WR47_07570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR47_07585	COG3852	Histidine kinase
WR47_07590	COG1801	Protein of unknown function DUF72
WR47_07600	COG0582	viral genome integration into host DNA
WR47_07605	COG5002	protein histidine kinase activity
WR47_07620	COG0392	lysyltransferase activity
WR47_07620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WR47_07635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR47_07640	COG1686	Belongs to the peptidase S11 family
WR47_07645	COG2715	membrane protein required for spore maturation
WR47_07650	COG0700	Nucleoside recognition
WR47_07655	COG1187	pseudouridine synthase activity
WR47_07665	COG1333	cytochrome c biogenesis protein
WR47_07670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR47_07675	COG0745	RESPONSE REGULATOR receiver
WR47_07680	COG5002	protein histidine kinase activity
WR47_07685	COG2096	Adenosyltransferase
WR47_07700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
WR47_07705	COG1141	Ferredoxin
WR47_07715	COG0514	ATP-dependent DNA helicase (RecQ)
WR47_07720	COG1266	CAAX protease self-immunity
WR47_07730	COG1408	metallophosphoesterase
WR47_07735	COG0789	Transcriptional regulator
WR47_07745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WR47_07765	COG0492	ferredoxin-NADP+ reductase activity
WR47_07770	COG0252	asparaginase activity
WR47_07840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR47_07855	COG0142	geranyltranstransferase activity
WR47_07865	COG0142	geranyltranstransferase activity
WR47_07890	COG0457	Tetratricopeptide repeat
WR47_07910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR47_07915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR47_07915	COG2010	Cytochrome c
WR47_07920	COG4347	Protein of unknown function (DUF1405)
WR47_07935	COG2738	Putative neutral zinc metallopeptidase
WR47_07945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_07950	COG1694	Mazg nucleotide pyrophosphohydrolase
WR47_07970	COG0438	transferase activity, transferring glycosyl groups
WR47_08010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WR47_08010	COG1199	ATP-dependent helicase activity
WR47_08030	COG3935	DnaD domain protein
WR47_08035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WR47_08045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR47_08045	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR47_08095	COG0116	Belongs to the methyltransferase superfamily
WR47_08105	COG1199	ATP-dependent helicase activity
WR47_08110	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WR47_08120	COG0024	Methionine aminopeptidase
WR47_08130	COG2233	PERMEase
WR47_08140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR47_08150	COG0456	acetyltransferase
WR47_08190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR47_08205	COG3944	biosynthesis protein
WR47_08215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR47_08230	COG1215	transferase activity, transferring glycosyl groups
WR47_08235	COG0438	transferase activity, transferring glycosyl groups
WR47_08270	COG0328	RNA-DNA hybrid ribonuclease activity
WR47_08305	COG3403	YqcI/YcgG family
WR47_08310	COG1280	lysine exporter protein (LysE YggA)
WR47_08330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR47_08335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR47_08345	COG0475	glutathione-regulated potassium exporter activity
WR47_08350	COG4978	Transcriptional regulator
WR47_08350	COG0789	Transcriptional regulator
WR47_08360	COG2323	membrane
WR47_08365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WR47_08375	COG2801	Transposase and inactivated derivatives
WR47_08435	COG1923	regulation of RNA biosynthetic process
WR47_08445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR47_08450	COG1360	Flagellar Motor Protein
WR47_08455	COG2201	protein-glutamate methylesterase activity
WR47_08460	COG2198	Histidine kinase
WR47_08460	COG0643	Histidine kinase
WR47_08465	COG1776	CheC inhibitor of MCP methylation
WR47_08465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR47_08480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR47_08500	COG1256	bacterial-type flagellum assembly
WR47_08505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR47_08525	COG1815	bacterial-type flagellum-dependent cell motility
WR47_08530	COG1558	bacterial-type flagellum-dependent cell motility
WR47_08535	COG1677	Flagellar hook-basal body complex protein FliE
WR47_08540	COG1766	The M ring may be actively involved in energy transduction
WR47_08545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR47_08555	COG1157	protein secretion by the type III secretion system
WR47_08575	COG1749	Flagellar hook protein flgE
WR47_08590	COG0835	chemotaxis
WR47_08590	COG0784	Response regulator, receiver
WR47_08605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR47_08610	COG0741	lytic transglycosylase activity
WR47_08620	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR47_08625	COG1776	CheC inhibitor of MCP methylation
WR47_08625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR47_08635	COG1338	Plays a role in the flagellum-specific transport system
WR47_08640	COG1987	bacterial-type flagellum assembly
WR47_08650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR47_08655	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR47_08660	COG1419	protein localization to endoplasmic reticulum
WR47_08665	COG4786	Flagellar basal body rod
WR47_08675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR47_08710	COG2329	Antibiotic biosynthesis monooxygenase
WR47_08740	COG3842	ATPase activity
WR47_08750	COG1177	transmembrane transport
WR47_08780	COG0406	alpha-ribazole phosphatase activity
WR47_08810	COG0367	asparagine synthase
WR47_08840	COG1802	Transcriptional regulator
WR47_08845	COG0697	spore germination
WR47_08855	COG0523	cobalamin synthesis protein
WR47_08860	COG0701	Predicted permease
WR47_08875	COG1757	Na H antiporter
WR47_08880	COG0789	Transcriptional regulator
WR47_08915	COG0534	Mate efflux family protein
WR47_08920	COG3340	Belongs to the peptidase S51 family
WR47_08940	COG0785	Cytochrome C biogenesis protein
WR47_08945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR47_08955	COG0457	Tetratricopeptide repeat
WR47_08975	COG2733	membrane
WR47_09010	COG1131	(ABC) transporter
WR47_09025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR47_09030	COG0528	UMP kinase activity
WR47_09040	COG1027	Aspartate ammonia-lyase
WR47_09045	COG0281	malic enzyme
WR47_09050	COG4191	Histidine kinase
WR47_09055	COG0784	Response regulator, receiver
WR47_09060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR47_09120	COG2814	Major facilitator Superfamily
WR47_09140	COG1695	Transcriptional regulator
WR47_09150	COG0477	Major facilitator Superfamily
WR47_09165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR47_09170	COG2223	nitrite transmembrane transporter activity
WR47_09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR47_09195	COG0733	neurotransmitter:sodium symporter activity
WR47_09205	COG5566	PFAM Mor transcription activator
WR47_09210	COG2323	membrane
WR47_09230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR47_09240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR47_09245	COG0028	Belongs to the TPP enzyme family
WR47_09265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WR47_09290	COG2814	Major facilitator Superfamily
WR47_09295	COG3384	dioxygenase
WR47_09305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR47_09310	COG3279	Response regulator of the LytR AlgR family
WR47_09315	COG0427	acetyl-CoA hydrolase
WR47_09350	COG4166	transmembrane transport
WR47_09380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_09400	COG1914	H( )-stimulated, divalent metal cation uptake system
WR47_09415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR47_09425	COG0531	amino acid
WR47_09435	COG0083	homoserine kinase activity
WR47_09450	COG2309	aminopeptidase activity
WR47_09470	COG0456	acetyltransferase
WR47_09485	COG1309	transcriptional regulator
WR47_09490	COG2390	Transcriptional regulator
WR47_09500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_09505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WR47_09515	COG4846	Membrane protein involved in cytochrome C biogenesis
WR47_09535	COG0583	DNA-binding transcription factor activity
WR47_09550	COG0006	proline dipeptidase activity
WR47_09560	COG2132	Multicopper oxidase
WR47_09590	COG1114	Component of the transport system for branched-chain amino acids
WR47_09600	COG1276	copper resistance
WR47_09600	COG2372	response to copper ion
WR47_09605	COG4549	nuclear export factor GLE1
WR47_09610	COG0697	spore germination
WR47_09615	COG0583	DNA-binding transcription factor activity
WR47_09620	COG1959	2 iron, 2 sulfur cluster binding
WR47_09625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR47_09630	COG0778	Nitroreductase
WR47_09645	COG0628	permease
WR47_09655	COG1231	oxidoreductase activity
WR47_09660	COG0523	cobalamin synthesis protein
WR47_09670	COG0411	ABC transporter
WR47_09690	COG0583	DNA-binding transcription factor activity
WR47_09700	COG1942	4-Oxalocrotonate Tautomerase
WR47_09720	COG1271	oxidase subunit
WR47_09725	COG1294	oxidase, subunit
WR47_09730	COG4988	ABC transporter
WR47_09735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WR47_09745	COG1216	Glycosyl transferase, family 2
WR47_09785	COG1686	Belongs to the peptidase S11 family
WR47_09800	COG1388	LysM domain
WR47_09800	COG0791	NLP P60 protein
WR47_09810	COG1132	(ABC) transporter
WR47_09815	COG0745	RESPONSE REGULATOR receiver
WR47_09820	COG5002	protein histidine kinase activity
WR47_09830	COG0300	oxidoreductase activity
WR47_09845	COG0726	polysaccharide deacetylase
WR47_09865	COG0460	homoserine dehydrogenase
WR47_09890	COG1316	TRANSCRIPTIONal
WR47_09900	COG0745	RESPONSE REGULATOR receiver
WR47_09905	COG5002	protein histidine kinase activity
WR47_09910	COG0726	polysaccharide deacetylase
WR47_09920	COG1285	pathogenesis
WR47_09925	COG1247	-acetyltransferase
WR47_09935	COG4264	IucA IucC family
WR47_09940	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_09955	COG1082	Xylose isomerase domain protein TIM barrel
WR47_09965	COG2814	Major facilitator Superfamily
WR47_09970	COG1279	arginine transmembrane transporter activity
WR47_09975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_09985	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR47_10020	COG0577	efflux transmembrane transporter activity
WR47_10025	COG2002	toxin-antitoxin pair type II binding
WR47_10030	COG1404	Belongs to the peptidase S8 family
WR47_10035	COG0640	Transcriptional regulator
WR47_10040	COG0667	Aldo Keto reductase
WR47_10070	COG0840	transmembrane signaling receptor activity
WR47_10090	COG3949	Membrane
WR47_10095	COG0783	Belongs to the Dps family
WR47_10110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR47_10120	COG1231	oxidoreductase activity
WR47_10125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_10130	COG4989	oxidoreductase activity
WR47_10135	COG0523	cobalamin synthesis protein
WR47_10140	COG0456	acetyltransferase
WR47_10145	COG0803	Belongs to the bacterial solute-binding protein 9 family
WR47_10155	COG0702	epimerase
WR47_10165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR47_10175	COG4166	transmembrane transport
WR47_10200	COG5337	Spore coat protein CotH
WR47_10205	COG1051	belongs to the nudix hydrolase family
WR47_10210	COG0586	Pfam SNARE associated Golgi protein
WR47_10215	COG2244	polysaccharide biosynthetic process
WR47_10225	COG0701	Predicted permease
WR47_10230	COG3689	TIGRFAM TIGR03943 family protein
WR47_10235	COG1607	acyl-coa hydrolase
WR47_10240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR47_10255	COG0702	epimerase
WR47_10260	COG2839	Protein conserved in bacteria
WR47_10265	COG1253	flavin adenine dinucleotide binding
WR47_10280	COG1114	Component of the transport system for branched-chain amino acids
WR47_10285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR47_10305	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR47_10315	COG1876	peptidase activity
WR47_10330	COG2211	Major facilitator Superfamily
WR47_10335	COG2801	Transposase and inactivated derivatives
WR47_10355	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR47_10365	COG0561	phosphatase activity
WR47_10370	COG1846	Transcriptional regulator
WR47_10375	COG2814	Major facilitator Superfamily
WR47_10385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR47_10405	COG1819	glycosyl
WR47_10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_10415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_10445	COG0456	acetyltransferase
WR47_10495	COG3874	Sporulation protein YtfJ
WR47_10520	COG2226	methyltransferase
WR47_10540	COG1082	Xylose isomerase domain protein TIM barrel
WR47_10545	COG0346	lactoylglutathione lyase activity
WR47_10555	COG0604	alcohol dehydrogenase
WR47_10560	COG1595	DNA-templated transcription, initiation
WR47_10575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR47_10575	COG0426	domain, Protein
WR47_10585	COG0386	Belongs to the glutathione peroxidase family
WR47_10590	COG1305	Transglutaminase-like
WR47_10595	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
WR47_10600	COG0714	Associated with various cellular activities
WR47_10605	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WR47_10610	COG1140	nitrate reductase beta subunit
WR47_10615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WR47_10620	COG2181	nitrate reductase activity
WR47_10625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR47_10630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR47_10635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR47_10640	COG0303	'Molybdopterin
WR47_10645	COG0314	molybdopterin synthase activity
WR47_10655	COG2223	nitrite transmembrane transporter activity
WR47_10675	COG1648	precorrin-2 dehydrogenase activity
WR47_10685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WR47_10685	COG1587	Uroporphyrinogen-III synthase
WR47_10690	COG2146	nitrite reductase [NAD(P)H] activity
WR47_10695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR47_10700	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
WR47_10735	COG2359	stage V sporulation protein S
WR47_10755	COG1418	mRNA catabolic process
WR47_10760	COG0488	(ABC) transporter
WR47_10775	COG0629	single-stranded DNA binding
WR47_10790	COG1413	lyase activity
WR47_10805	COG2136	Putative SAM-dependent methyltransferase
WR47_10805	COG2521	methyltransferase
WR47_10810	COG0018	arginyl-trna synthetase
WR47_10850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR47_10855	COG0017	Asparaginyl-tRNA synthetase
WR47_10875	COG1674	ftsk spoiiie
WR47_10980	COG0733	neurotransmitter:sodium symporter activity
WR47_11005	COG2610	gluconate transmembrane transporter activity
WR47_11015	COG1794	racemase activity, acting on amino acids and derivatives
WR47_11025	COG0456	acetyltransferase
WR47_11035	COG3655	Transcriptional regulator
WR47_11040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WR47_11050	COG1131	(ABC) transporter
WR47_11055	COG4473	ABC transporter
WR47_11065	COG0546	phosphoglycolate phosphatase activity
WR47_11080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_11095	COG0768	penicillin binding
WR47_11105	COG0204	Acyl-transferase
WR47_11110	COG1272	protein, Hemolysin III
WR47_11120	COG0805	protein transport
WR47_11130	COG1307	EDD domain protein, DegV family
WR47_11140	COG1999	signal sequence binding
WR47_11145	COG0071	Belongs to the small heat shock protein (HSP20) family
WR47_11150	COG0367	asparagine synthase
WR47_11165	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR47_11170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_11175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR47_11195	COG1335	isochorismatase
WR47_11205	COG0668	transmembrane transport
WR47_11210	COG2203	Gaf domain
WR47_11210	COG4585	Histidine kinase
WR47_11215	COG2197	response regulator
WR47_11220	COG1737	Transcriptional regulator
WR47_11225	COG0384	phenazine biosynthesis protein PhzF
WR47_11230	COG1064	alcohol dehydrogenase
WR47_11255	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR47_11290	COG1125	glycine betaine transport
WR47_11290	COG0517	IMP dehydrogenase activity
WR47_11295	COG1174	glycine betaine transport
WR47_11330	COG1253	flavin adenine dinucleotide binding
WR47_11335	COG1012	belongs to the aldehyde dehydrogenase family
WR47_11340	COG5506	Protein of unknown function (DUF1694)
WR47_11355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR47_11360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WR47_11365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WR47_11370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR47_11375	COG0456	acetyltransferase
WR47_11380	COG3829	transcription factor binding
WR47_11385	COG1509	lysine 2,3-aminomutase activity
WR47_11420	COG3064	Membrane
WR47_11420	COG0515	serine threonine protein kinase
WR47_11420	COG4991	sh3 domain protein
WR47_11430	COG0671	phosphoesterase, PA-phosphatase related
WR47_11435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR47_11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR47_11540	COG0300	oxidoreductase activity
WR47_11560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR47_11560	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR47_11570	COG2814	Major facilitator Superfamily
WR47_11575	COG4841	protein insertion into membrane
WR47_11580	COG0372	Belongs to the citrate synthase family
WR47_11585	COG2079	MmgE PrpD family protein
WR47_11590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WR47_11595	COG1960	acyl-CoA dehydrogenase activity
WR47_11600	COG2084	Dehydrogenase
WR47_11610	COG1280	lysine exporter protein (LysE YggA)
WR47_11615	COG1024	Enoyl-CoA hydratase
WR47_11630	COG0420	3'-5' exonuclease activity
WR47_11635	COG0419	ATPase involved in DNA repair
WR47_11660	COG2223	nitrite transmembrane transporter activity
WR47_11665	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_11670	COG1169	isochorismate synthase
WR47_11675	COG1021	2,3-dihydroxybenzoate-AMP ligase
WR47_11680	COG1535	isochorismatase
WR47_11680	COG3433	isochorismatase activity
WR47_11685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR47_11690	COG3251	PFAM MbtH domain protein
WR47_11695	COG2814	Major facilitator Superfamily
WR47_11710	COG0776	regulation of translation
WR47_11720	COG2318	DinB family
WR47_11730	COG1115	amino acid carrier protein
WR47_11750	COG1187	pseudouridine synthase activity
WR47_11755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR47_11760	COG1136	(ABC) transporter
WR47_11775	COG0028	Belongs to the TPP enzyme family
WR47_11810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR47_11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_11850	COG2801	Transposase and inactivated derivatives
WR47_11870	COG1247	-acetyltransferase
WR47_11905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_11935	COG0583	DNA-binding transcription factor activity
WR47_11940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR47_11960	COG0583	DNA-binding transcription factor activity
WR47_11965	COG2258	MOSC domain
WR47_11980	COG1132	(ABC) transporter
WR47_11985	COG1132	(ABC) transporter
WR47_12005	COG0582	viral genome integration into host DNA
WR47_12025	COG1396	sequence-specific DNA binding
WR47_12065	COG2002	toxin-antitoxin pair type II binding
WR47_12105	COG0582	viral genome integration into host DNA
WR47_12145	COG1802	Transcriptional regulator
WR47_12145	COG4626	Terminase
WR47_12155	COG0740	serine-type endopeptidase activity
WR47_12225	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_12255	COG1396	sequence-specific DNA binding
WR47_12290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR47_12295	COG1595	DNA-templated transcription, initiation
WR47_12320	COG1649	PFAM Uncharacterised BCR, COG1649
WR47_12345	COG2971	BadF BadG BcrA BcrD
WR47_12355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WR47_12365	COG1846	Transcriptional regulator
WR47_12380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_12400	COG1309	transcriptional regulator
WR47_12495	COG0500	methyltransferase
WR47_12495	COG3615	Tellurite resistance protein tehB
WR47_12505	COG2226	methyltransferase
WR47_12510	COG3961	Belongs to the TPP enzyme family
WR47_12515	COG1846	Transcriptional regulator
WR47_12565	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR47_12595	COG2002	toxin-antitoxin pair type II binding
WR47_12605	COG0730	response to heat
WR47_12610	COG0110	maltose O-acetyltransferase activity
WR47_12615	COG1686	Belongs to the peptidase S11 family
WR47_12630	COG2814	Major facilitator Superfamily
WR47_12665	COG1115	amino acid carrier protein
WR47_12670	COG2066	Belongs to the glutaminase family
WR47_12675	COG4191	Histidine kinase
WR47_12680	COG0784	Response regulator, receiver
WR47_12685	COG0697	spore germination
WR47_12690	COG0531	amino acid
WR47_12700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR47_12705	COG0531	amino acid
WR47_12710	COG0322	excinuclease ABC activity
WR47_12720	COG2207	Transcriptional regulator
WR47_12745	COG5002	protein histidine kinase activity
WR47_12790	COG0741	lytic transglycosylase activity
WR47_12795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_12810	COG1396	sequence-specific DNA binding
WR47_12825	COG0726	polysaccharide deacetylase
WR47_12830	COG1309	transcriptional regulator
WR47_12835	COG0367	asparagine synthase
WR47_12840	COG4585	Histidine kinase
WR47_12850	COG1404	Belongs to the peptidase S8 family
WR47_12895	COG0768	penicillin binding
WR47_12900	COG1595	DNA-templated transcription, initiation
WR47_12925	COG1408	metallophosphoesterase
WR47_12935	COG1131	(ABC) transporter
WR47_12945	COG1309	transcriptional regulator
WR47_12960	COG1960	acyl-CoA dehydrogenase activity
WR47_12965	COG0439	Biotin carboxylase
WR47_12970	COG0511	ligase activity, forming carbon-carbon bonds
WR47_12975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WR47_12980	COG1024	Enoyl-CoA hydratase
WR47_12985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WR47_12990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR47_13020	COG1686	Belongs to the peptidase S11 family
WR47_13045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR47_13060	COG3227	Zinc metalloprotease (Elastase)
WR47_13065	COG2207	Transcriptional regulator
WR47_13095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR47_13105	COG2814	Major facilitator Superfamily
WR47_13110	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_13115	COG1733	regulation of RNA biosynthetic process
WR47_13160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_13170	COG2368	4-hydroxyphenylacetate
WR47_13185	COG1063	alcohol dehydrogenase
WR47_13195	COG2323	membrane
WR47_13200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WR47_13205	COG0693	protein deglycase activity
WR47_13215	COG3386	PFAM SMP-30 Gluconolaconase
WR47_13225	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WR47_13230	COG3773	Cell wall hydrolase
WR47_13240	COG0745	RESPONSE REGULATOR receiver
WR47_13245	COG2205	protein histidine kinase activity
WR47_13270	COG1136	(ABC) transporter
WR47_13275	COG0577	efflux transmembrane transporter activity
WR47_13295	COG0460	homoserine dehydrogenase
WR47_13300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_13310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR47_13335	COG0582	viral genome integration into host DNA
WR47_13360	COG1396	sequence-specific DNA binding
WR47_13390	COG1484	DNA-dependent DNA replication
WR47_13410	COG2002	toxin-antitoxin pair type II binding
WR47_13490	COG0582	viral genome integration into host DNA
WR47_13520	COG5484	DNA packaging
WR47_13535	COG0740	serine-type endopeptidase activity
WR47_13655	COG2124	cytochrome p450
WR47_13690	COG0561	phosphatase activity
WR47_13695	COG5002	protein histidine kinase activity
WR47_13710	COG1819	glycosyl
WR47_13715	COG1794	racemase activity, acting on amino acids and derivatives
WR47_13735	COG2205	protein histidine kinase activity
WR47_13800	COG0604	alcohol dehydrogenase
WR47_13805	COG0671	phosphoesterase, PA-phosphatase related
WR47_13820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_13865	COG2814	Major facilitator Superfamily
WR47_13880	COG0584	glycerophosphoryl diester phosphodiesterase
WR47_13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_13905	COG0697	spore germination
WR47_13950	COG2223	nitrite transmembrane transporter activity
WR47_13965	COG0592	DNA-directed DNA polymerase activity
WR47_14000	COG3878	Protein conserved in bacteria
WR47_14025	COG4667	esterase of the alpha-beta hydrolase superfamily
WR47_14065	COG0322	excinuclease ABC activity
WR47_14105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR47_14135	COG0745	RESPONSE REGULATOR receiver
WR47_14140	COG5002	protein histidine kinase activity
WR47_14150	COG3813	Protein conserved in bacteria
WR47_14155	COG1522	sequence-specific DNA binding
WR47_14170	COG1136	(ABC) transporter
WR47_14175	COG0577	efflux transmembrane transporter activity
WR47_14190	COG0076	glutamate decarboxylase activity
WR47_14205	COG1523	belongs to the glycosyl hydrolase 13 family
WR47_14210	COG3227	Zinc metalloprotease (Elastase)
WR47_14215	COG0737	Belongs to the 5'-nucleotidase family
WR47_14230	COG0201	protein transport
WR47_14245	COG0697	spore germination
WR47_14250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_14260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR47_14290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_14305	COG2959	enzyme of heme biosynthesis
WR47_14310	COG3409	Peptidoglycan-binding domain 1 protein
WR47_14310	COG3773	Cell wall hydrolase
WR47_14345	COG1309	transcriptional regulator
WR47_14375	COG3284	Transcriptional regulator
WR47_14395	COG1349	DNA-binding transcription factor activity
WR47_14410	COG1959	2 iron, 2 sulfur cluster binding
WR47_14425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR47_14430	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR47_14435	COG0022	dehydrogenase e1 component
WR47_14440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR47_14450	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_14455	COG0456	acetyltransferase
WR47_14455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR47_14495	COG4176	ABC-type proline glycine betaine transport system permease component
WR47_14500	COG4175	Glycine betaine
WR47_14500	COG0517	IMP dehydrogenase activity
WR47_14510	COG0740	serine-type endopeptidase activity
WR47_14530	COG2153	protein acetylation
WR47_14535	COG3397	chitin binding
WR47_14540	COG1819	glycosyl
WR47_14565	COG2315	Protein conserved in bacteria
WR47_14610	COG0456	acetyltransferase
WR47_14615	COG3973	AAA domain
WR47_14630	COG0514	ATP-dependent DNA helicase (RecQ)
WR47_14655	COG2801	Transposase and inactivated derivatives
WR47_14670	COG4637	Psort location Cytoplasmic, score
WR47_14690	COG3397	chitin binding
WR47_14705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WR47_14710	COG1115	amino acid carrier protein
WR47_14715	COG1012	belongs to the aldehyde dehydrogenase family
WR47_14720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WR47_14730	COG3938	Belongs to the proline racemase family
WR47_14735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR47_14775	COG0586	Pfam SNARE associated Golgi protein
WR47_14785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR47_14790	COG4166	transmembrane transport
WR47_14800	COG4948	Mandelate Racemase Muconate Lactonizing
WR47_14815	COG0667	Aldo Keto reductase
WR47_14855	COG3850	Histidine kinase
WR47_14855	COG5002	protein histidine kinase activity
WR47_14860	COG0745	RESPONSE REGULATOR receiver
WR47_14900	COG1164	Oligoendopeptidase f
WR47_14905	COG1307	EDD domain protein, DegV family
WR47_14945	COG2814	Major facilitator Superfamily
WR47_14955	COG1664	Polymer-forming cytoskeletal
WR47_14960	COG0789	Transcriptional regulator
WR47_14965	COG4533	DNA binding
WR47_14970	COG0477	Major facilitator Superfamily
WR47_14970	COG2814	Major facilitator Superfamily
WR47_14995	COG2261	transglycosylase associated protein
WR47_15010	COG2226	methyltransferase
WR47_15050	COG0436	Aminotransferase
WR47_15055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WR47_15065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WR47_15080	COG1131	(ABC) transporter
WR47_15140	COG0628	permease
WR47_15155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR47_15160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR47_15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR47_15205	COG2746	aminoglycoside 3-N-acetyltransferase activity
WR47_15215	COG0697	spore germination
WR47_15240	COG4912	Dna alkylation repair
WR47_15245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR47_15250	COG0346	lactoylglutathione lyase activity
WR47_15255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_15265	COG0726	polysaccharide deacetylase
WR47_15270	COG3037	sugar-specific permease SgaT UlaA
WR47_15280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR47_15285	COG0861	Integral membrane protein TerC family
WR47_15290	COG1368	sulfuric ester hydrolase activity
WR47_15295	COG0488	(ABC) transporter
WR47_15300	COG2409	Drug exporters of the RND superfamily
WR47_15300	COG1033	growth of symbiont in host cell
WR47_15305	COG1309	transcriptional regulator
WR47_15310	COG1051	belongs to the nudix hydrolase family
WR47_15325	COG0287	Prephenate dehydrogenase
WR47_15340	COG1605	Chorismate mutase
WR47_15340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR47_15385	COG1388	LysM domain
WR47_15385	COG3584	3D domain protein
WR47_15395	COG0277	FAD linked oxidase domain protein
WR47_15420	COG1879	ABC-type sugar transport system periplasmic component
WR47_15425	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR47_15430	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR47_15440	COG2390	Transcriptional regulator
WR47_15445	COG1070	Carbohydrate kinase
WR47_15465	COG2329	Antibiotic biosynthesis monooxygenase
WR47_15480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_15495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR47_15500	COG4187	Peptidase family M20/M25/M40
WR47_15505	COG1414	Transcriptional regulator
WR47_15510	COG0833	amino acid
WR47_15525	COG3239	Fatty acid desaturase
WR47_15535	COG2720	vancomycin resistance protein
WR47_15540	COG1785	Belongs to the alkaline phosphatase family
WR47_15550	COG3655	Transcriptional regulator
WR47_15575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_15580	COG0346	lactoylglutathione lyase activity
WR47_15605	COG0714	Associated with various cellular activities
WR47_15625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WR47_15630	COG0753	catalase activity
WR47_15665	COG0778	Nitroreductase
WR47_15670	COG1846	Transcriptional regulator
WR47_15705	COG1725	Transcriptional regulator
WR47_15710	COG4282	regulation of fungal-type cell wall biogenesis
WR47_15735	COG0456	acetyltransferase
WR47_15750	COG0697	spore germination
WR47_15755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_15795	COG0730	response to heat
WR47_15805	COG0833	amino acid
WR47_15815	COG4335	DNA alkylation repair
WR47_15880	COG1984	allophanate hydrolase subunit 2
WR47_15885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WR47_15890	COG1414	Transcriptional regulator
WR47_15905	COG3142	Participates in the control of copper homeostasis
WR47_15910	COG0640	Transcriptional regulator
WR47_15920	COG1960	acyl-CoA dehydrogenase activity
WR47_15955	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
WR47_15980	COG0574	Belongs to the PEP-utilizing enzyme family
WR47_15980	COG3848	Pyruvate phosphate dikinase
WR47_15985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_16005	COG1063	alcohol dehydrogenase
WR47_16015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR47_16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR47_16040	COG0737	Belongs to the 5'-nucleotidase family
WR47_16045	COG2267	carboxylic ester hydrolase activity
WR47_16050	COG1335	isochorismatase
WR47_16070	COG0583	DNA-binding transcription factor activity
WR47_16075	COG1846	Transcriptional regulator
WR47_16080	COG0598	Magnesium transport protein CorA
WR47_16120	COG0415	Belongs to the DNA photolyase family
WR47_16135	COG0288	reversible hydration of carbon dioxide
WR47_16145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR47_16150	COG5609	conserved protein (DUF2294)
WR47_16155	COG0726	polysaccharide deacetylase
WR47_16165	COG1575	Belongs to the MenA family. Type 1 subfamily
WR47_16185	COG0798	PFAM Bile acid sodium symporter
WR47_16190	COG0346	lactoylglutathione lyase activity
WR47_16195	COG0640	Transcriptional regulator
WR47_16215	COG2169	Transcriptional regulator
WR47_16235	COG2814	Major facilitator Superfamily
WR47_16240	COG1309	transcriptional regulator
WR47_16245	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_16250	COG1522	sequence-specific DNA binding
WR47_16265	COG0346	lactoylglutathione lyase activity
WR47_16295	COG0814	amino acid
WR47_16300	COG0583	DNA-binding transcription factor activity
WR47_16330	COG1131	(ABC) transporter
WR47_16335	COG1725	Transcriptional regulator
WR47_16380	COG0745	RESPONSE REGULATOR receiver
WR47_16385	COG5002	protein histidine kinase activity
WR47_16385	COG3850	Histidine kinase
WR47_16425	COG1136	(ABC) transporter
WR47_16460	COG2814	Major facilitator Superfamily
WR47_16485	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WR47_16495	COG1690	Belongs to the RtcB family
WR47_16505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
WR47_16525	COG0577	efflux transmembrane transporter activity
WR47_16545	COG5002	protein histidine kinase activity
WR47_16545	COG3850	Histidine kinase
WR47_16555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_16565	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR47_16585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WR47_16605	COG0662	Cupin 2, conserved barrel domain protein
WR47_16610	COG2207	Transcriptional regulator
WR47_16610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_16630	COG3409	Peptidoglycan-binding domain 1 protein
WR47_16630	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_16640	COG2814	Major facilitator Superfamily
WR47_16660	COG1876	peptidase activity
WR47_16665	COG2843	Capsule synthesis protein
WR47_16675	COG0477	Major facilitator Superfamily
WR47_16690	COG1846	Transcriptional regulator
WR47_16695	COG2814	Major facilitator Superfamily
WR47_16705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR47_16710	COG1131	(ABC) transporter
WR47_16730	COG2076	Multidrug Resistance protein
WR47_16735	COG1309	transcriptional regulator
WR47_16755	COG2031	fatty acid transporter
WR47_16765	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR47_16800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR47_16820	COG1288	antiporter activity
WR47_16825	COG2356	endonuclease I
WR47_16855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WR47_16875	COG1733	regulation of RNA biosynthetic process
WR47_16880	COG0778	Nitroreductase
WR47_16910	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_16920	COG1131	(ABC) transporter
WR47_16950	COG1011	Hydrolase
WR47_16985	COG0346	lactoylglutathione lyase activity
WR47_16990	COG1940	carbohydrate kinase activity
WR47_17000	COG0110	maltose O-acetyltransferase activity
WR47_17005	COG0180	Tryptophanyl-tRNA synthetase
WR47_17015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_17030	COG0628	permease
WR47_17050	COG0500	methyltransferase
WR47_17060	COG0477	Major facilitator Superfamily
WR47_17100	COG1253	flavin adenine dinucleotide binding
WR47_17105	COG0789	Transcriptional regulator
WR47_17115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR47_17140	COG0697	spore germination
WR47_17150	COG1357	PFAM Pentapeptide repeats (8 copies)
WR47_17155	COG3813	Protein conserved in bacteria
WR47_17160	COG2706	6-phosphogluconolactonase activity
WR47_17165	COG1070	Carbohydrate kinase
WR47_17180	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR47_17185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WR47_17190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR47_17195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR47_17230	COG0814	amino acid
WR47_17260	COG2188	Transcriptional regulator
WR47_17265	COG0673	inositol 2-dehydrogenase activity
WR47_17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_17305	COG0384	phenazine biosynthesis protein PhzF
WR47_17320	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_17325	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR47_17330	COG1733	regulation of RNA biosynthetic process
WR47_17335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR47_17350	COG2801	Transposase and inactivated derivatives
WR47_17360	COG0726	polysaccharide deacetylase
WR47_17370	COG1191	sigma factor activity
WR47_17405	COG1280	lysine exporter protein (LysE YggA)
WR47_17450	COG1151	hydroxylamine reductase activity
WR47_17460	COG3757	hydrolase, family 25
WR47_17460	COG3409	Peptidoglycan-binding domain 1 protein
WR47_17495	COG2072	flavoprotein involved in K transport
WR47_17530	COG0604	alcohol dehydrogenase
WR47_17535	COG1113	amino acid transport
WR47_17540	COG2814	Major facilitator Superfamily
WR47_17570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
WR47_17575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR47_17590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_17595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_17600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_17605	COG3739	integral membrane protein
WR47_17625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_17640	COG0583	DNA-binding transcription factor activity
WR47_17675	COG2162	N-hydroxyarylamine O-acetyltransferase activity
WR47_17680	COG1164	Oligoendopeptidase f
WR47_17710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_17735	COG0584	glycerophosphoryl diester phosphodiesterase
WR47_17780	COG0640	Transcriptional regulator
WR47_17785	COG0604	alcohol dehydrogenase
WR47_17795	COG0457	Tetratricopeptide repeat
WR47_17805	COG2808	Putative FMN-binding domain
WR47_17820	COG0277	FAD linked oxidase domain protein
WR47_17835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_17835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_17840	COG1252	NADH dehydrogenase
WR47_17855	COG0584	glycerophosphoryl diester phosphodiesterase
WR47_17890	COG0823	Involved in the tonB-independent uptake of proteins
WR47_17895	COG3397	chitin binding
WR47_17905	COG0697	spore germination
WR47_17925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR47_17935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR47_17950	COG0457	Tetratricopeptide repeat
WR47_17975	COG1404	Belongs to the peptidase S8 family
WR47_18000	COG5001	Diguanylate cyclase
WR47_18000	COG3300	MHYT domain
WR47_18010	COG1309	transcriptional regulator
WR47_18025	COG1876	peptidase activity
WR47_18050	COG3852	Histidine kinase
WR47_18060	COG1285	pathogenesis
WR47_18070	COG2514	catechol 2,3-dioxygenase activity
WR47_18075	COG2720	vancomycin resistance protein
WR47_18105	COG1278	Cold shock
WR47_18115	COG0716	FMN binding
WR47_18125	COG1051	belongs to the nudix hydrolase family
WR47_18145	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_18155	COG0165	Argininosuccinate lyase
WR47_18170	COG4145	pantothenate transmembrane transporter activity
WR47_18180	COG1012	belongs to the aldehyde dehydrogenase family
WR47_18185	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_18195	COG1657	PFAM Prenyltransferase squalene oxidase
WR47_18200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
WR47_18205	COG2962	Rard protein
WR47_18210	COG3326	Membrane
WR47_18225	COG0489	protein tyrosine kinase activity
WR47_18235	COG0314	molybdopterin synthase activity
WR47_18240	COG0303	'Molybdopterin
WR47_18245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR47_18250	COG2116	formate transmembrane transporter activity
WR47_18260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR47_18265	COG5609	conserved protein (DUF2294)
WR47_18270	COG2427	Protein of unknown function (DUF1641)
WR47_18275	COG3383	formate dehydrogenase (NAD+) activity
WR47_18285	COG0697	spore germination
WR47_18300	COG0531	amino acid
WR47_18335	COG2226	methyltransferase
WR47_18340	COG4166	transmembrane transport
WR47_18350	COG2801	Transposase and inactivated derivatives
WR47_18355	COG4166	transmembrane transport
WR47_18360	COG4166	transmembrane transport
WR47_18365	COG1316	TRANSCRIPTIONal
WR47_18375	COG1595	DNA-templated transcription, initiation
WR47_18385	COG1131	(ABC) transporter
WR47_18405	COG0673	inositol 2-dehydrogenase activity
WR47_18410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR47_18415	COG0187	DNA topoisomerase II activity
WR47_18425	COG1832	CoA-binding protein
WR47_18430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR47_18435	COG0745	RESPONSE REGULATOR receiver
WR47_18455	COG4841	protein insertion into membrane
WR47_18460	COG0824	Thioesterase
WR47_18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR47_18495	COG2274	protein secretion by the type I secretion system
WR47_18500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WR47_18510	COG0726	polysaccharide deacetylase
WR47_18530	COG2211	Major facilitator Superfamily
WR47_18540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR47_18555	COG0183	Belongs to the thiolase family
WR47_18560	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_18565	COG1268	BioY protein
WR47_18570	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_18580	COG5002	protein histidine kinase activity
WR47_18595	COG1136	(ABC) transporter
WR47_18610	COG1131	(ABC) transporter
WR47_18700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_18710	COG5002	protein histidine kinase activity
WR47_18715	COG0400	carboxylic ester hydrolase activity
WR47_18720	COG0346	lactoylglutathione lyase activity
WR47_18725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR47_18730	COG0069	glutamate synthase activity
WR47_18735	COG1902	pentaerythritol trinitrate reductase activity
WR47_18740	COG1329	Transcriptional regulator
WR47_18745	COG0010	Belongs to the arginase family
WR47_18770	COG2226	methyltransferase
WR47_18800	COG4846	Membrane protein involved in cytochrome C biogenesis
WR47_18805	COG0785	Cytochrome C biogenesis protein
WR47_18825	COG1131	(ABC) transporter
WR47_18840	COG0583	DNA-binding transcription factor activity
WR47_18850	COG1346	cytolysis
WR47_18865	COG0730	response to heat
WR47_18890	COG1132	(ABC) transporter
WR47_18895	COG1132	(ABC) transporter
WR47_18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR47_18935	COG0737	Belongs to the 5'-nucleotidase family
WR47_18945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WR47_18965	COG1695	Transcriptional regulator
WR47_18975	COG3409	Peptidoglycan-binding domain 1 protein
WR47_18975	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_18975	COG1388	LysM domain
WR47_19015	COG0174	glutamine synthetase
WR47_19020	COG0789	Transcriptional regulator
WR47_19025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
WR47_19030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR47_19035	COG2860	membrane
WR47_19045	COG0464	growth
WR47_19075	COG3584	3D domain protein
WR47_19075	COG1388	LysM domain
WR47_19080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR47_19080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR47_19080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR47_19085	COG1105	Belongs to the carbohydrate kinase PfkB family
WR47_19090	COG1349	DNA-binding transcription factor activity
WR47_19095	COG1979	alcohol dehydrogenase
WR47_19100	COG2322	membrane
WR47_19115	COG1113	amino acid transport
WR47_19130	COG1408	metallophosphoesterase
WR47_19135	COG2116	formate transmembrane transporter activity
WR47_19150	COG2217	Heavy metal translocating P-type atpase
WR47_19155	COG2608	mercury ion transmembrane transporter activity
WR47_19160	COG2801	Transposase and inactivated derivatives
WR47_19170	COG1937	Protein conserved in bacteria
WR47_19180	COG2819	hydrolase of the alpha beta superfamily
WR47_19185	COG1120	ATPase activity
WR47_19190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_19195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_19200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_19205	COG0708	Exodeoxyribonuclease III
WR47_19210	COG2169	Transcriptional regulator
WR47_19215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR47_19220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR47_19230	COG2364	Membrane
WR47_19245	COG2267	carboxylic ester hydrolase activity
WR47_19250	COG5001	Diguanylate cyclase
WR47_19250	COG3300	MHYT domain
WR47_19270	COG1086	Polysaccharide biosynthesis protein
WR47_19290	COG1346	cytolysis
WR47_19300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_19310	COG2188	Transcriptional regulator
WR47_19315	COG2723	6-phospho-beta-galactosidase activity
WR47_19325	COG1404	Belongs to the peptidase S8 family
WR47_19330	COG3773	Cell wall hydrolase
WR47_19340	COG1368	sulfuric ester hydrolase activity
WR47_19345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR47_19370	COG4550	Control of competence regulator ComK, YlbF/YmcA
WR47_19380	COG1013	pyruvate-flavodoxin oxidoreductase activity
WR47_19385	COG0674	pyruvate-flavodoxin oxidoreductase activity
WR47_19385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WR47_19395	COG2359	stage V sporulation protein S
WR47_19400	COG1692	metallophosphoesterase
WR47_19425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WR47_19430	COG1426	Protein conserved in bacteria
WR47_19445	COG0300	oxidoreductase activity
WR47_19450	COG0612	Peptidase, M16
WR47_19455	COG0612	Peptidase, M16
WR47_19480	COG2188	Transcriptional regulator
WR47_19500	COG0740	serine-type endopeptidase activity
WR47_19505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR47_19515	COG0527	aspartate kinase activity
WR47_19520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR47_19525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR47_19540	COG5444	nuclease activity
WR47_19550	COG0582	viral genome integration into host DNA
WR47_19600	COG0305	Participates in initiation and elongation during chromosome replication
WR47_19660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR47_19665	COG1873	PFAM PRC-barrel domain
WR47_19670	COG0612	Peptidase, M16
WR47_19675	COG0726	polysaccharide deacetylase
WR47_19690	COG0196	riboflavin kinase activity
WR47_19705	COG1550	Protein conserved in bacteria
WR47_19715	COG1358	cellular component organization or biogenesis
WR47_19720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
WR47_19725	COG0195	Participates in both transcription termination and antitermination
WR47_19745	COG0750	zinc metalloprotease
WR47_19755	COG4589	Belongs to the CDS family
WR47_19800	COG4974	Belongs to the 'phage' integrase family
WR47_19810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WR47_19815	COG0758	DNA mediated transformation
WR47_19820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WR47_19860	COG1837	Belongs to the UPF0109 family
WR47_19870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WR47_19880	COG0552	protein localization to endoplasmic reticulum
WR47_19885	COG1196	nuclear chromosome segregation
WR47_19900	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_19905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WR47_19920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WR47_19925	COG1461	Dihydroxyacetone kinase
WR47_19930	COG1302	Protein conserved in bacteria
WR47_19945	COG1564	THIamine pyrophosphokinase
WR47_19950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WR47_19960	COG0515	serine threonine protein kinase
WR47_19960	COG2815	serine threonine protein kinase
WR47_19965	COG0631	protein serine/threonine phosphatase activity
WR47_19975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WR47_19975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WR47_19990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WR47_19995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR47_20015	COG1561	YicC-like family, N-terminal region
WR47_20020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WR47_20035	COG0006	proline dipeptidase activity
WR47_20055	COG3069	C4-dicarboxylate transmembrane transporter activity
WR47_20120	COG0564	pseudouridine synthase activity
WR47_20140	COG3599	regulation of cell shape
WR47_20145	COG2302	S4 RNA-binding domain
WR47_20150	COG0762	integral membrane protein
WR47_20160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WR47_20170	COG1873	PFAM PRC-barrel domain
WR47_20175	COG1191	sigma factor activity
WR47_20180	COG1191	sigma factor activity
WR47_20190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WR47_20195	COG0849	cell division
WR47_20210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WR47_20215	COG0772	Belongs to the SEDS family
WR47_20235	COG0768	penicillin binding
WR47_20260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR47_20280	COG1399	metal-binding, possibly nucleic acid-binding protein
WR47_20290	COG3480	Lon protease (S16) C-terminal proteolytic domain
WR47_20295	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR47_20300	COG3314	Sporulation integral membrane protein YlbJ
WR47_20310	COG0742	ribosomal rna small subunit methyltransferase
WR47_20325	COG3679	Belongs to the UPF0342 family
WR47_20330	COG0406	alpha-ribazole phosphatase activity
WR47_20345	COG2340	Cysteine-rich secretory protein family
WR47_20360	COG3336	cytochrome c oxidase
WR47_20395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
WR47_20400	COG0772	Belongs to the SEDS family
WR47_20410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WR47_20415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WR47_20425	COG4896	Protein conserved in bacteria
WR47_20450	COG0483	inositol monophosphate 1-phosphatase activity
WR47_20470	COG1982	Orn Lys Arg decarboxylase major
WR47_20520	COG0022	dehydrogenase e1 component
WR47_20525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR47_20540	COG0561	phosphatase activity
WR47_20550	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR47_20555	COG0569	domain protein
WR47_20575	COG0583	DNA-binding transcription factor activity
WR47_20580	COG0517	IMP dehydrogenase activity
WR47_20590	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
WR47_20600	COG4703	Protein of unknown function (DUF1797)
WR47_20615	COG2200	EAL domain
WR47_20620	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_20625	COG1408	metallophosphoesterase
WR47_20670	COG2814	Major facilitator Superfamily
WR47_20695	COG3209	COG3209 Rhs family protein
WR47_20705	COG2205	protein histidine kinase activity
WR47_20715	COG0436	Aminotransferase
WR47_20720	COG1609	Transcriptional regulator
WR47_20725	COG3833	ABC-type maltose transport systems, permease component
WR47_20730	COG1175	transmembrane transport
WR47_20735	COG2182	Extracellular solute-binding protein
WR47_20745	COG0366	Alpha amylase catalytic
WR47_20750	COG3842	ATPase activity
WR47_20790	COG0183	Belongs to the thiolase family
WR47_20825	COG1695	Transcriptional regulator
WR47_20830	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_20850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WR47_20855	COG0436	Aminotransferase
WR47_20890	COG2084	Dehydrogenase
WR47_20900	COG2199	diguanylate cyclase activity
WR47_20900	COG2203	Gaf domain
WR47_20905	COG0778	Nitroreductase
WR47_20930	COG2190	(PTS) system
WR47_20930	COG1263	PTS System
WR47_20930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR47_20935	COG3711	transcriptional antiterminator
WR47_20955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WR47_20985	COG1547	Domain of unknown function (DUF309)
WR47_20990	COG0456	acetyltransferase
WR47_20995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WR47_21000	COG4086	secreted protein
WR47_21005	COG0561	phosphatase activity
WR47_21010	COG0697	spore germination
WR47_21025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR47_21050	COG0733	neurotransmitter:sodium symporter activity
WR47_21070	COG1686	Belongs to the peptidase S11 family
WR47_21075	COG1725	Transcriptional regulator
WR47_21080	COG1131	(ABC) transporter
WR47_21095	COG1846	Transcriptional regulator
WR47_21110	COG0598	Magnesium transport protein CorA
WR47_21135	COG4974	Belongs to the 'phage' integrase family
WR47_21145	COG0735	belongs to the Fur family
WR47_21150	COG1300	Membrane
WR47_21170	COG0667	Aldo Keto reductase
WR47_21175	COG0656	L-ascorbic acid biosynthetic process
WR47_21180	COG0456	acetyltransferase
WR47_21180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR47_21190	COG4085	toxin activity
WR47_21190	COG1525	nuclease
WR47_21190	COG0737	Belongs to the 5'-nucleotidase family
WR47_21200	COG0596	Alpha beta hydrolase
WR47_21205	COG2056	Na+-H+ antiporter family
WR47_21210	COG1609	Transcriptional regulator
WR47_21215	COG0456	acetyltransferase
WR47_21220	COG1073	alpha beta
WR47_21235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR47_21235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR47_21240	COG0307	riboflavin synthase, alpha
WR47_21270	COG2226	methyltransferase
WR47_21270	COG1073	alpha beta
WR47_21285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR47_21300	COG0737	Belongs to the 5'-nucleotidase family
WR47_21310	COG1522	sequence-specific DNA binding
WR47_21350	COG5444	nuclease activity
WR47_21385	COG0300	oxidoreductase activity
WR47_21390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_21395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR47_21400	COG1760	l-serine dehydratase
WR47_21405	COG1760	l-serine dehydratase
WR47_21440	COG1285	pathogenesis
WR47_21455	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR47_21460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_21475	COG1376	ErfK ybiS ycfS ynhG family protein
WR47_21480	COG4129	membrane
WR47_21485	COG1126	abc transporter atp-binding protein
WR47_21490	COG0765	amino acid transport
WR47_21495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR47_21520	COG2323	membrane
WR47_21525	COG0772	Belongs to the SEDS family
WR47_21535	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR47_21540	COG0022	dehydrogenase e1 component
WR47_21545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR47_21550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR47_21560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WR47_21565	COG0280	phosphate acetyltransferase
WR47_21575	COG3290	protein histidine kinase activity
WR47_21575	COG3829	transcription factor binding
WR47_21585	COG0584	glycerophosphoryl diester phosphodiesterase
WR47_21590	COG3093	addiction module antidote protein HigA
WR47_21610	COG0750	zinc metalloprotease
WR47_21615	COG0497	DNA recombination
WR47_21625	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WR47_21635	COG0142	geranyltranstransferase activity
WR47_21660	COG1302	Protein conserved in bacteria
WR47_21665	COG0439	Biotin carboxylase
WR47_21670	COG0511	ligase activity, forming carbon-carbon bonds
WR47_21715	COG3854	ATPases associated with a variety of cellular activities
WR47_21740	COG0006	proline dipeptidase activity
WR47_21755	COG3872	metal-dependent enzyme
WR47_21765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WR47_21800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_21810	COG1609	Transcriptional regulator
WR47_21820	COG2076	Multidrug Resistance protein
WR47_21825	COG2076	Multidrug Resistance protein
WR47_21865	COG1725	Transcriptional regulator
WR47_21895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR47_21960	COG1459	type II secretion system
WR47_21965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WR47_22030	COG0646	methionine synthase
WR47_22030	COG1410	methionine synthase
WR47_22035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WR47_22035	COG0646	methionine synthase
WR47_22040	COG0626	cystathionine gamma-synthase activity
WR47_22045	COG0626	cystathionine gamma-synthase activity
WR47_22065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_22075	COG1940	carbohydrate kinase activity
WR47_22080	COG4483	Protein conserved in bacteria
WR47_22085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WR47_22095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR47_22100	COG0704	Plays a role in the regulation of phosphate uptake
WR47_22110	COG0573	inorganic phosphate transmembrane transporter activity
WR47_22115	COG0573	inorganic phosphate transmembrane transporter activity
WR47_22120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR47_22130	COG0477	Major facilitator Superfamily
WR47_22135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR47_22145	COG5521	maltodextrose utilization protein MalA
WR47_22160	COG0735	belongs to the Fur family
WR47_22165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WR47_22170	COG1121	(ABC) transporter
WR47_22175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_22205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WR47_22210	COG2384	SAM-dependent methyltransferase
WR47_22220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WR47_22225	COG0358	DNA primase activity
WR47_22240	COG0517	IMP dehydrogenase activity
WR47_22255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WR47_22260	COG0295	cytidine deaminase activity
WR47_22265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WR47_22275	COG1480	7TM receptor with intracellular HD hydrolase
WR47_22280	COG1702	phosphate starvation-inducible protein PhoH
WR47_22300	COG1610	YqeY-like protein
WR47_22310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WR47_22315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WR47_22345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR47_22350	COG1733	regulation of RNA biosynthetic process
WR47_22375	COG1466	dna polymerase III delta subunit
WR47_22385	COG2333	competence protein COMEC
WR47_22385	COG0658	competence protein
WR47_22390	COG2131	deaminase
WR47_22395	COG1555	photosystem II stabilization
WR47_22395	COG1596	polysaccharide export
WR47_22400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR47_22405	COG2226	methyltransferase
WR47_22410	COG0799	negative regulation of ribosome biogenesis
WR47_22415	COG1713	HD superfamily hydrolase involved in NAD metabolism
WR47_22425	COG1534	Rna-binding protein
WR47_22435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WR47_22440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
WR47_22455	COG1191	sigma factor activity
WR47_22465	COG1595	DNA-templated transcription, initiation
WR47_22475	COG0778	Nitroreductase
WR47_22480	COG2357	RelA SpoT domain protein
WR47_22490	COG1785	Belongs to the alkaline phosphatase family
WR47_22500	COG2267	carboxylic ester hydrolase activity
WR47_22540	COG3186	Phenylalanine-4-hydroxylase
WR47_22550	COG2514	catechol 2,3-dioxygenase activity
WR47_22555	COG2259	Doxx family
WR47_22595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_22605	COG1454	alcohol dehydrogenase
WR47_22605	COG1012	belongs to the aldehyde dehydrogenase family
WR47_22610	COG0626	cystathionine gamma-synthase activity
WR47_22615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR47_22640	COG0768	penicillin binding
WR47_22670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WR47_22700	COG0628	permease
WR47_22720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WR47_22735	COG1104	cysteine desulfurase activity
WR47_22740	COG1959	2 iron, 2 sulfur cluster binding
WR47_22745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WR47_22760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WR47_22785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WR47_22795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WR47_22795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
WR47_22800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR47_22805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR47_22805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR47_22815	COG2244	polysaccharide biosynthetic process
WR47_22820	COG2323	membrane
WR47_22830	COG1862	Preprotein translocase
WR47_22860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
WR47_22890	COG0157	Belongs to the NadC ModD family
WR47_22900	COG1104	cysteine desulfurase activity
WR47_22905	COG1827	regulation of RNA biosynthetic process
WR47_22910	COG2258	MOSC domain
WR47_22915	COG0077	Prephenate dehydratase
WR47_22920	COG0577	efflux transmembrane transporter activity
WR47_22925	COG0577	efflux transmembrane transporter activity
WR47_22930	COG1136	(ABC) transporter
WR47_22935	COG5002	protein histidine kinase activity
WR47_22940	COG0745	RESPONSE REGULATOR receiver
WR47_22950	COG3290	protein histidine kinase activity
WR47_22960	COG2868	ribosomal protein
WR47_22970	COG1530	ribonuclease E activity
WR47_22975	COG1994	Peptidase M50
WR47_22980	COG0739	heme binding
WR47_22985	COG2894	cell division
WR47_23000	COG1792	Involved in formation and maintenance of cell shape
WR47_23005	COG1077	Cell shape determining protein MreB Mrl
WR47_23025	COG0285	dihydrofolate synthase activity
WR47_23040	COG1388	LysM domain
WR47_23050	COG0113	porphobilinogen synthase activity
WR47_23055	COG1587	Uroporphyrinogen-III synthase
WR47_23065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR47_23075	COG1846	Transcriptional regulator
WR47_23080	COG1764	response to oxidative stress
WR47_23095	COG0470	DNA polymerase III
WR47_23095	COG1067	ATP-dependent peptidase activity
WR47_23145	COG0622	Phosphoesterase
WR47_23160	COG5401	PFAM Sporulation and spore germination
WR47_23180	COG1309	transcriptional regulator
WR47_23190	COG2197	response regulator
WR47_23195	COG2233	PERMEase
WR47_23200	COG0402	S-adenosylhomocysteine deaminase activity
WR47_23205	COG1983	PspC domain protein
WR47_23210	COG1396	sequence-specific DNA binding
WR47_23215	COG0697	spore germination
WR47_23225	COG1959	2 iron, 2 sulfur cluster binding
WR47_23230	COG1668	transmembrane transport
WR47_23235	COG4152	abc transporter atp-binding protein
WR47_23240	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
WR47_23245	COG1360	Flagellar Motor Protein
WR47_23250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR47_23255	COG1876	peptidase activity
WR47_23260	COG0824	Thioesterase
WR47_23265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WR47_23270	COG1053	succinate dehydrogenase
WR47_23275	COG2009	succinate dehydrogenase
WR47_23280	COG1719	4-vinyl reductase, 4VR
WR47_23290	COG3118	belongs to the thioredoxin family
WR47_23295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WR47_23300	COG2086	electron transfer activity
WR47_23305	COG1024	Enoyl-CoA hydratase
WR47_23310	COG1309	transcriptional regulator
WR47_23315	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_23340	COG2318	DinB family
WR47_23370	COG1131	(ABC) transporter
WR47_23375	COG2205	protein histidine kinase activity
WR47_23380	COG0745	RESPONSE REGULATOR receiver
WR47_23390	COG4895	conserved protein (DUF2196)
WR47_23395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WR47_23405	COG4509	Sortase family
WR47_23410	COG1120	ATPase activity
WR47_23425	COG5386	Cell surface protein
WR47_23435	COG5386	Cell surface protein
WR47_23440	COG1114	Component of the transport system for branched-chain amino acids
WR47_23445	COG1187	pseudouridine synthase activity
WR47_23460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR47_23460	COG1796	DNA polymerase
WR47_23465	COG1286	toxin biosynthetic process
WR47_23510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR47_23520	COG1418	mRNA catabolic process
WR47_23540	COG2814	Major facilitator Superfamily
WR47_23545	COG1566	PFAM secretion protein HlyD family protein
WR47_23550	COG1309	transcriptional regulator
WR47_23555	COG1363	Peptidase, m42
WR47_23580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR47_23595	COG1484	DNA-dependent DNA replication
WR47_23600	COG3611	Membrane attachment protein
WR47_23610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WR47_23615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR47_23620	COG0237	dephospho-CoA kinase activity
WR47_23625	COG1971	Probably functions as a manganese efflux pump
WR47_23635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR47_23635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR47_23640	COG5002	protein histidine kinase activity
WR47_23645	COG0745	RESPONSE REGULATOR receiver
WR47_23665	COG0538	isocitrate dehydrogenase activity
WR47_23670	COG0372	Belongs to the citrate synthase family
WR47_23685	COG0628	permease
WR47_23690	COG3030	protein affecting phage T7 exclusion by the F plasmid
WR47_23715	COG1725	Transcriptional regulator
WR47_23720	COG0281	malic enzyme
WR47_23725	COG0587	DNA-directed DNA polymerase activity
WR47_23740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WR47_23755	COG4109	DRTGG domain
WR47_23770	COG0006	proline dipeptidase activity
WR47_23805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_23810	COG0662	Cupin 2, conserved barrel domain protein
WR47_23825	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_23830	COG0589	response to stress
WR47_23870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_23895	COG0827	DNA restriction-modification system
WR47_23900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WR47_23905	COG3874	Sporulation protein YtfJ
WR47_23920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WR47_23930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR47_23945	COG1104	cysteine desulfurase activity
WR47_23965	COG1136	(ABC) transporter
WR47_23990	COG0583	DNA-binding transcription factor activity
WR47_23995	COG0697	spore germination
WR47_24000	COG1309	transcriptional regulator
WR47_24005	COG1956	GAF domain-containing protein
WR47_24010	COG0626	cystathionine gamma-synthase activity
WR47_24040	COG1595	DNA-templated transcription, initiation
WR47_24050	COG0110	maltose O-acetyltransferase activity
WR47_24055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR47_24060	COG0454	-acetyltransferase
WR47_24065	COG0517	IMP dehydrogenase activity
WR47_24070	COG0123	including yeast histone deacetylase and acetoin utilization protein
WR47_24075	COG2267	carboxylic ester hydrolase activity
WR47_24085	COG0745	RESPONSE REGULATOR receiver
WR47_24090	COG5002	protein histidine kinase activity
WR47_24095	COG0666	response to abiotic stimulus
WR47_24125	COG1609	Transcriptional regulator
WR47_24135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR47_24135	COG1605	Chorismate mutase
WR47_24140	COG1605	Chorismate mutase
WR47_24140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR47_24145	COG4851	CamS sex pheromone cAM373 precursor
WR47_24150	COG3118	belongs to the thioredoxin family
WR47_24160	COG2309	aminopeptidase activity
WR47_24180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_24185	COG0697	spore germination
WR47_24190	COG0789	Transcriptional regulator
WR47_24205	COG1674	ftsk spoiiie
WR47_24210	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR47_24220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR47_24230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR47_24235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
WR47_24240	COG1363	Peptidase, m42
WR47_24250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_24265	COG0510	thiamine kinase activity
WR47_24270	COG1523	belongs to the glycosyl hydrolase 13 family
WR47_24285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR47_24290	COG1349	DNA-binding transcription factor activity
WR47_24295	COG1187	pseudouridine synthase activity
WR47_24300	COG2244	polysaccharide biosynthetic process
WR47_24305	COG2081	HI0933 family
WR47_24310	COG2814	Major facilitator Superfamily
WR47_24320	COG3832	glyoxalase III activity
WR47_24340	COG1329	Transcriptional regulator
WR47_24365	COG0314	molybdopterin synthase activity
WR47_24370	COG1763	Mo-molybdopterin cofactor biosynthetic process
WR47_24375	COG0303	'Molybdopterin
WR47_24385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR47_24390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR47_24410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR47_24420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR47_24460	COG2814	Major facilitator Superfamily
WR47_24465	COG0475	glutathione-regulated potassium exporter activity
WR47_24470	COG0490	domain, Protein
WR47_24475	COG0582	viral genome integration into host DNA
WR47_24485	COG1136	(ABC) transporter
WR47_24505	COG1242	4 iron, 4 sulfur cluster binding
WR47_24510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
WR47_24525	COG1794	racemase activity, acting on amino acids and derivatives
WR47_24545	COG2267	carboxylic ester hydrolase activity
WR47_24550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WR47_24555	COG0671	phosphoesterase, PA-phosphatase related
WR47_24560	COG0438	transferase activity, transferring glycosyl groups
WR47_24650	COG5002	protein histidine kinase activity
WR47_24655	COG3852	Histidine kinase
WR47_24665	COG2267	carboxylic ester hydrolase activity
WR47_24670	COG1368	sulfuric ester hydrolase activity
WR47_24690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR47_24695	COG1116	anion transmembrane transporter activity
WR47_24700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR47_24715	COG0546	phosphoglycolate phosphatase activity
WR47_24725	COG0494	nUDIX hydrolase
WR47_24765	COG0288	reversible hydration of carbon dioxide
WR47_24770	COG1271	oxidase subunit
WR47_24775	COG1294	oxidase, subunit
WR47_24790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_24810	COG1842	Phage shock protein A
WR47_24835	COG3859	Proton-coupled thiamine transporter YuaJ
WR47_24840	COG5002	protein histidine kinase activity
WR47_24845	COG0745	RESPONSE REGULATOR receiver
WR47_24875	COG1597	lipid kinase activity
WR47_24905	COG0586	Pfam SNARE associated Golgi protein
WR47_24915	COG0577	efflux transmembrane transporter activity
WR47_24920	COG1136	(ABC) transporter
WR47_24925	COG3708	Transcriptional regulator
WR47_24925	COG2207	Transcriptional regulator
WR47_24935	COG5658	integral membrane protein
WR47_24940	COG0640	Transcriptional regulator
WR47_24945	COG0745	RESPONSE REGULATOR receiver
WR47_24950	COG2205	protein histidine kinase activity
WR47_24955	COG0577	efflux transmembrane transporter activity
WR47_24960	COG0577	efflux transmembrane transporter activity
WR47_24965	COG1136	(ABC) transporter
WR47_24970	COG0577	efflux transmembrane transporter activity
WR47_25015	COG3964	amidohydrolase
WR47_25035	COG4948	Mandelate Racemase Muconate Lactonizing
WR47_25045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WR47_25050	COG0596	Alpha beta hydrolase
WR47_25060	COG1169	isochorismate synthase
WR47_25065	COG1575	Belongs to the MenA family. Type 1 subfamily
WR47_25070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WR47_25075	COG1278	Cold shock
WR47_25105	COG0058	SHG alpha-glucan phosphorylase activity
WR47_25115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WR47_25135	COG1404	Belongs to the peptidase S8 family
WR47_25270	COG1285	pathogenesis
WR47_25275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR47_25295	COG2155	Conserved Protein
WR47_25300	COG1098	S1 RNA binding domain
WR47_25305	COG0436	Aminotransferase
WR47_25310	COG1522	sequence-specific DNA binding
WR47_25315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR47_25320	COG2267	carboxylic ester hydrolase activity
WR47_25330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WR47_25350	COG5018	Exonuclease
WR47_25355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR47_25370	COG0423	glycine-tRNA ligase activity
WR47_25375	COG2050	protein possibly involved in aromatic compounds catabolism
WR47_25385	COG1268	BioY protein
WR47_25395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR47_25400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WR47_25420	COG2076	Multidrug Resistance protein
WR47_25425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WR47_25435	COG3584	3D domain protein
WR47_25450	COG1252	NADH dehydrogenase
WR47_25460	COG3708	Transcriptional regulator
WR47_25475	COG1683	Conserved Protein
WR47_25500	COG0316	Belongs to the HesB IscA family
WR47_25515	COG1252	NADH dehydrogenase
WR47_25525	COG2274	protein secretion by the type I secretion system
WR47_25530	COG0390	transport system, permease component
WR47_25535	COG2824	Alkylphosphonate utilization operon protein PhnA
WR47_25560	COG4837	Protein of unknown function (DUF1462)
WR47_25565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WR47_25575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR47_25580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WR47_25600	COG1358	cellular component organization or biogenesis
WR47_25610	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR47_25615	COG0647	UMP catabolic process
WR47_25625	COG2445	Protein of unknown function DUF86
WR47_25630	COG1494	fructose-1,6-bisphosphatase
WR47_25655	COG4470	Protein conserved in bacteria
WR47_25665	COG0789	Transcriptional regulator
WR47_25670	COG4377	Putative membrane peptidase family (DUF2324)
WR47_25695	COG0739	heme binding
WR47_25705	COG3377	Domain of unknown function (DUF1805)
WR47_25710	COG0737	Belongs to the 5'-nucleotidase family
WR47_25715	COG0719	Fe-S assembly protein
WR47_25720	COG0822	iron-sulfur transferase activity
WR47_25725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WR47_25730	COG0719	Fe-S assembly protein
WR47_25735	COG0396	ATPase activity
WR47_25740	COG1464	Belongs to the NlpA lipoprotein family
WR47_25745	COG1464	Belongs to the NlpA lipoprotein family
WR47_25750	COG2011	ABC-type metal ion transport system permease component
WR47_25765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR47_25770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
WR47_25780	COG1393	Belongs to the ArsC family
WR47_25815	COG0039	L-malate dehydrogenase activity
WR47_25835	COG1309	transcriptional regulator
WR47_25840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR47_25845	COG1960	acyl-CoA dehydrogenase activity
WR47_25850	COG0183	Belongs to the thiolase family
WR47_25855	COG1024	Enoyl-CoA hydratase
WR47_25855	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR47_25865	COG1686	Belongs to the peptidase S11 family
WR47_25880	COG0011	TIGRFAM Protein of
WR47_25885	COG0840	transmembrane signaling receptor activity
WR47_25900	COG2814	Major facilitator Superfamily
WR47_25905	COG0531	amino acid
WR47_25930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR47_25965	COG0586	Pfam SNARE associated Golgi protein
WR47_25975	COG1376	ErfK ybiS ycfS ynhG family protein
WR47_25980	COG0745	RESPONSE REGULATOR receiver
WR47_25985	COG5002	protein histidine kinase activity
WR47_26015	COG0840	transmembrane signaling receptor activity
WR47_26020	COG2151	metal-sulfur cluster biosynthetic enzyme
WR47_26025	COG3227	Zinc metalloprotease (Elastase)
WR47_26045	COG0586	Pfam SNARE associated Golgi protein
WR47_26050	COG0475	glutathione-regulated potassium exporter activity
WR47_26055	COG0490	domain, Protein
WR47_26065	COG1115	amino acid carrier protein
WR47_26070	COG0783	Belongs to the Dps family
WR47_26080	COG2318	DinB family
WR47_26090	COG1611	Belongs to the LOG family
WR47_26100	COG1528	Iron-storage protein
WR47_26110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_26115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_26120	COG1115	amino acid carrier protein
WR47_26125	COG1115	amino acid carrier protein
WR47_26130	COG2910	NAD(P)H-binding
WR47_26145	COG0656	L-ascorbic acid biosynthetic process
WR47_26150	COG2814	Major facilitator Superfamily
WR47_26155	COG1733	regulation of RNA biosynthetic process
WR47_26165	COG1252	NADH dehydrogenase
WR47_26170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WR47_26215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_26220	COG3223	Belongs to the PsiE family
WR47_26230	COG1335	isochorismatase
WR47_26235	COG1522	sequence-specific DNA binding
WR47_26245	COG1522	sequence-specific DNA binding
WR47_26250	COG0288	reversible hydration of carbon dioxide
WR47_26255	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
WR47_26260	COG2233	PERMEase
WR47_26305	COG0557	exoribonuclease II activity
WR47_26310	COG1647	Serine aminopeptidase, S33
WR47_26315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR47_26320	COG1346	cytolysis
WR47_26355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR47_26370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WR47_26380	COG1668	transmembrane transport
WR47_26385	COG4152	abc transporter atp-binding protein
WR47_26390	COG4585	Histidine kinase
WR47_26455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR47_26470	COG2323	membrane
WR47_26480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR47_26490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WR47_26500	COG1051	belongs to the nudix hydrolase family
WR47_26510	COG0492	ferredoxin-NADP+ reductase activity
WR47_26515	COG0457	Tetratricopeptide repeat
WR47_26520	COG0110	maltose O-acetyltransferase activity
WR47_26540	COG1950	PFAM Membrane protein of
WR47_26545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR47_26565	COG0789	Transcriptional regulator
WR47_26585	COG0583	DNA-binding transcription factor activity
WR47_26595	COG0655	NAD(P)H dehydrogenase (quinone) activity
WR47_26600	COG0488	(ABC) transporter
WR47_26610	COG1132	(ABC) transporter
WR47_26615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR47_26620	COG0793	Belongs to the peptidase S41A family
WR47_26620	COG3409	Peptidoglycan-binding domain 1 protein
WR47_26625	COG2177	Part of the ABC transporter FtsEX involved in
WR47_26630	COG2884	Cell division ATP-binding protein ftsE
WR47_26645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WR47_26660	COG1131	(ABC) transporter
WR47_26690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WR47_26695	COG1278	Cold shock
WR47_26700	COG1040	competence protein
WR47_26705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
WR47_26710	COG1388	LysM domain
WR47_26710	COG0791	NLP P60 protein
WR47_26715	COG1733	regulation of RNA biosynthetic process
WR47_26720	COG1307	EDD domain protein, DegV family
WR47_26725	COG1739	Uncharacterized protein family UPF0029
WR47_26730	COG1316	TRANSCRIPTIONal
WR47_26735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WR47_26740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR47_26745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WR47_26755	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WR47_26755	COG3933	PFAM sigma-54 factor interaction domain-containing protein
WR47_26775	COG1486	melibiose metabolic process
WR47_26780	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR47_26785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR47_26795	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WR47_26805	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR47_26815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR47_26820	COG1301	dicarboxylic acid transport
WR47_26835	COG1511	domain protein
WR47_26840	COG0583	DNA-binding transcription factor activity
WR47_26845	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WR47_26855	COG1271	oxidase subunit
WR47_26860	COG1294	oxidase, subunit
WR47_26865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR47_26875	COG1620	l-lactate permease
WR47_26885	COG2389	metal-binding protein
WR47_26895	COG1368	sulfuric ester hydrolase activity
WR47_26905	COG1388	LysM domain
WR47_26905	COG0791	NLP P60 protein
WR47_26910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR47_26920	COG1215	transferase activity, transferring glycosyl groups
WR47_26930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR47_26935	COG1388	LysM domain
WR47_26935	COG3584	3D domain protein
WR47_26960	COG4715	Zinc finger, swim domain protein
WR47_26965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR47_26995	COG1191	sigma factor activity
WR47_27005	COG0577	efflux transmembrane transporter activity
WR47_27010	COG1136	(ABC) transporter
WR47_27035	COG5002	protein histidine kinase activity
WR47_27040	COG0745	RESPONSE REGULATOR receiver
WR47_27045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR47_27050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR47_27070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR47_27085	COG0438	transferase activity, transferring glycosyl groups
WR47_27090	COG1215	transferase activity, transferring glycosyl groups
WR47_27095	COG0438	transferase activity, transferring glycosyl groups
WR47_27110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR47_27115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR47_27120	COG1086	Polysaccharide biosynthesis protein
WR47_27125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR47_27130	COG4464	protein tyrosine phosphatase activity
WR47_27135	COG0489	protein tyrosine kinase activity
WR47_27140	COG3944	biosynthesis protein
WR47_27145	COG0489	protein tyrosine kinase activity
WR47_27160	COG1609	Transcriptional regulator
WR47_27170	COG0739	heme binding
WR47_27185	COG3279	Response regulator of the LytR AlgR family
WR47_27190	COG2385	sporulation resulting in formation of a cellular spore
WR47_27195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WR47_27205	COG4836	Membrane
WR47_27210	COG1007	ATP synthesis coupled electron transport
WR47_27215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR47_27220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR47_27230	COG0839	Belongs to the complex I subunit 6 family
WR47_27250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR47_27265	COG3300	MHYT domain
WR47_27265	COG5001	Diguanylate cyclase
WR47_27315	COG0356	it plays a direct role in the translocation of protons across the membrane
WR47_27350	COG0698	ribose 5-phosphate isomerase
WR47_27360	COG2190	(PTS) system
WR47_27365	COG2259	Doxx family
WR47_27370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR47_27390	COG0009	L-threonylcarbamoyladenylate synthase
WR47_27410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WR47_27425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WR47_27430	COG1494	fructose-1,6-bisphosphatase
WR47_27450	COG4821	SIS domain
WR47_27460	COG3343	RNA polymerase activity
WR47_27470	COG1960	acyl-CoA dehydrogenase activity
WR47_27475	COG1960	acyl-CoA dehydrogenase activity
WR47_27480	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR47_27485	COG0183	Belongs to the thiolase family
WR47_27490	COG2181	nitrate reductase activity
WR47_27490	COG0247	lactate metabolic process
WR47_27495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR47_27505	COG3300	MHYT domain
WR47_27505	COG5001	Diguanylate cyclase
WR47_27520	COG3227	Zinc metalloprotease (Elastase)
WR47_27525	COG2197	response regulator
WR47_27530	COG4585	Histidine kinase
WR47_27535	COG0842	Transport permease protein
WR47_27540	COG1131	(ABC) transporter
WR47_27545	COG0024	Methionine aminopeptidase
WR47_27555	COG2234	aminopeptidase activity
WR47_27575	COG1595	DNA-templated transcription, initiation
WR47_27585	COG4506	Protein conserved in bacteria
WR47_27590	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR47_27615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WR47_27620	COG2814	Major facilitator Superfamily
WR47_27625	COG0789	Transcriptional regulator
WR47_27630	COG0584	glycerophosphoryl diester phosphodiesterase
WR47_27635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR47_27645	COG1994	Peptidase M50
WR47_27655	COG1078	dGTPase activity
WR47_27660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR47_27665	COG1120	ATPase activity
WR47_27670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_27675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR47_27695	COG0280	phosphate acetyltransferase
WR47_27710	COG3773	Cell wall hydrolase
WR47_27720	COG2363	Small membrane protein
WR47_27730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR47_27735	COG2233	PERMEase
WR47_27740	COG0561	phosphatase activity
WR47_27745	COG2814	Major facilitator Superfamily
WR47_27755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR47_27760	COG1131	(ABC) transporter
WR47_27765	COG2755	lipolytic protein G-D-S-L family
WR47_27770	COG1609	Transcriptional regulator
WR47_27780	COG0460	homoserine dehydrogenase
WR47_27800	COG1011	Hydrolase
WR47_27805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR47_27815	COG2197	response regulator
WR47_27820	COG4585	Histidine kinase
WR47_27820	COG2203	Gaf domain
WR47_27825	COG0351	phosphomethylpyrimidine kinase
WR47_27830	COG3706	GGDEF domain
WR47_27835	COG2879	small protein
WR47_27840	COG1966	Carbon starvation protein
WR47_27845	COG3279	Response regulator of the LytR AlgR family
WR47_27850	COG0477	Major facilitator Superfamily
WR47_27860	COG0438	transferase activity, transferring glycosyl groups
WR47_27875	COG0840	transmembrane signaling receptor activity
WR47_27885	COG1607	acyl-coa hydrolase
WR47_27890	COG1216	Glycosyl transferase, family 2
WR47_27900	COG1216	Glycosyl transferase, family 2
WR47_27910	COG4485	Bacterial membrane protein, YfhO
WR47_27915	COG0463	Glycosyl transferase, family 2
WR47_27925	COG1309	transcriptional regulator
WR47_27930	COG0488	(ABC) transporter
WR47_27935	COG1309	transcriptional regulator
WR47_27940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR47_27945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR47_27945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR47_27950	COG0628	permease
WR47_27970	COG3275	phosphorelay sensor kinase activity
WR47_27975	COG2814	Major facilitator Superfamily
WR47_27980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR47_27985	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
WR47_28010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR47_28015	COG1272	protein, Hemolysin III
WR47_28035	COG1164	Oligoendopeptidase f
WR47_28045	COG5002	protein histidine kinase activity
WR47_28060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR47_28065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WR47_28070	COG4853	Protein conserved in bacteria
WR47_28080	COG5002	protein histidine kinase activity
WR47_28085	COG0745	RESPONSE REGULATOR receiver
WR47_28115	COG0305	Participates in initiation and elongation during chromosome replication
WR47_28125	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
WR47_28130	COG4241	membrane
WR47_28140	COG0629	single-stranded DNA binding
WR47_28150	COG0012	GTP binding
WR47_28155	COG4481	Protein conserved in bacteria
WR47_28160	COG0668	transmembrane transport
WR47_28170	COG1475	DNA binding
WR47_28175	COG1192	Involved in chromosome partitioning
WR47_28200	COG1847	R3H domain protein
WR47_28245	COG1404	Belongs to the peptidase S8 family
WR47_28255	COG5634	Uncharacterized conserved protein (DUF2278)
WR47_28365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_28385	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_28395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR47_28405	COG3104	oligopeptide transport
WR47_28410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR47_28415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR47_28420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR47_28425	COG0438	transferase activity, transferring glycosyl groups
WR47_28440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR47_28445	COG0438	transferase activity, transferring glycosyl groups
WR47_28450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR47_28455	COG2002	toxin-antitoxin pair type II binding
WR47_28465	COG0776	regulation of translation
WR47_28480	COG2423	ornithine cyclodeaminase activity
WR47_28520	COG2366	antibiotic biosynthetic process
WR47_28525	COG2211	Major facilitator Superfamily
WR47_28535	COG0697	spore germination
WR47_28540	COG1802	Transcriptional regulator
WR47_28545	COG0697	spore germination
WR47_28575	COG2002	toxin-antitoxin pair type II binding
WR47_28580	COG0776	regulation of translation
WR47_28615	COG2801	Transposase and inactivated derivatives
WR47_28630	COG1819	glycosyl
WR47_28655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR47_28685	COG0745	RESPONSE REGULATOR receiver
WR47_28690	COG2205	protein histidine kinase activity
WR47_28695	COG1136	(ABC) transporter
WR47_28700	COG0577	efflux transmembrane transporter activity
WR47_28720	COG0583	DNA-binding transcription factor activity
WR47_28725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
WR47_28765	COG0823	Involved in the tonB-independent uptake of proteins
WR47_28775	COG2311	Membrane
WR47_28885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR47_28905	COG2211	Major facilitator Superfamily
WR47_29275	COG0457	Tetratricopeptide repeat
WR47_29310	COG0494	nUDIX hydrolase
WR47_29315	COG0542	response to heat
WR47_29350	COG0463	Glycosyl transferase, family 2
WR47_29390	COG2234	aminopeptidase activity
WR47_29395	COG5634	Uncharacterized conserved protein (DUF2278)
WR47_29425	COG0741	lytic transglycosylase activity
WR47_29430	COG0739	heme binding
WR47_29435	COG3409	Peptidoglycan-binding domain 1 protein
WR47_29435	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_29435	COG1388	LysM domain
WR47_29450	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_29525	COG2274	protein secretion by the type I secretion system
WR47_29550	COG1396	sequence-specific DNA binding
WR47_29560	COG0726	polysaccharide deacetylase
WR47_29580	COG1309	transcriptional regulator
WR47_29585	COG0367	asparagine synthase
WR47_29625	COG3409	Peptidoglycan-binding domain 1 protein
WR47_29625	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR47_29630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR47_29670	COG1846	Transcriptional regulator
WR47_29670	COG0456	acetyltransferase
WR47_29680	COG0457	Tetratricopeptide repeat
WR47_29690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR47_29725	COG0210	DNA helicase
WR47_29785	COG1204	response to ionizing radiation
WR47_29795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WR47_29800	COG0210	DNA helicase
WR47_29830	COG1396	sequence-specific DNA binding
WR47_29845	COG3391	amine dehydrogenase activity
WR47_29860	COG0667	Aldo Keto reductase
WR47_29885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR47_29885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR47_29885	COG0300	oxidoreductase activity
WR47_29885	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_29885	COG3321	synthase
WR47_29885	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_29885	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_29885	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_29885	COG3321	synthase
WR47_29885	COG0300	oxidoreductase activity
WR47_29905	COG1960	acyl-CoA dehydrogenase activity
WR47_29920	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR47_29925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR47_29940	COG3321	synthase
WR47_29940	COG0300	oxidoreductase activity
WR47_29940	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_29940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR47_29940	COG1028	Short-chain dehydrogenase reductase Sdr
WR47_29945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR47_29980	COG1609	Transcriptional regulator
WR47_29985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR47_29990	COG0561	phosphatase activity
WR47_29995	COG0673	inositol 2-dehydrogenase activity
WR47_30000	COG0738	Major facilitator superfamily
WR47_30020	COG1475	DNA binding
WR47_30170	COG2318	DinB family
WR47_30175	COG1923	regulation of RNA biosynthetic process
WR47_30180	COG0457	Tetratricopeptide repeat
WR47_30215	COG4974	Belongs to the 'phage' integrase family
WR47_30225	COG0494	nUDIX hydrolase
WR47_30255	COG0457	Tetratricopeptide repeat
WR47_30265	COG0463	Glycosyl transferase, family 2
WR47_30270	COG0463	Glycosyl transferase, family 2
WR47_30275	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
WR47_30280	COG1086	Polysaccharide biosynthesis protein
WR47_30285	COG1088	dTDP-glucose 4,6-dehydratase activity
WR47_30290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR47_30295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WR47_30310	COG2089	acid synthase
WR47_30325	COG4641	Protein conserved in bacteria
WR47_30355	COG2814	Major facilitator Superfamily
WR47_30380	COG0318	PFAM AMP-dependent synthetase and ligase
WR47_30385	COG2259	Doxx family
WR47_30420	COG5549	protein import
WR47_30420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR47_30430	COG1404	Belongs to the peptidase S8 family
WR47_30440	COG4974	Belongs to the 'phage' integrase family
WR47_30505	COG2239	Acts as a magnesium transporter
WR47_30510	COG0772	Belongs to the SEDS family
WR47_30515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR47_30520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR47_30530	COG0456	acetyltransferase
WR47_30540	COG1309	transcriptional regulator
WR47_30560	COG0840	transmembrane signaling receptor activity
WR47_30575	COG0814	amino acid
WR47_30580	COG1760	l-serine dehydratase
WR47_30585	COG1760	l-serine dehydratase
WR47_30590	COG2814	Major facilitator Superfamily
WR47_30595	COG1309	transcriptional regulator
WR47_30600	COG2304	oxidoreductase activity