locus-tag class description BCE33L0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCE33L0003 ENOG410848D S4 domain protein YaaA BCE33L0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCE33L0009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCE33L0015 ENOG4105ZMH deoxynucleoside kinase BCE33L0017 ENOG4105GTG Isochorismatase BCE33L0018 ENOG4108Z6B deaminase BCE33L0019 ENOG4105C6E dna polymerase iii BCE33L0023 ENOG41067KS pro-sigma K processing BCE33L0025 ENOG4105CXN decarboxylase BCE33L0027 ENOG4105FA2 dna polymerase iii BCE33L0028 ENOG4105MA4 psp1 domain protein BCE33L0030 ENOG41060K3 Methyltransferase BCE33L0032 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCE33L0033 ENOG4105KRN Transcriptional regulator, abrb family BCE33L0035 ENOG4105F8V Hydrolase, tatD family BCE33L0036 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCE33L0038 ENOG4105XFA sporulation peptidase YabG BCE33L0039 ENOG4105W42 Veg protein BCE33L0041 ENOG4105DFT pur operon repressor BCE33L0042 ENOG4105KME endoribonuclease L-psp BCE33L0045 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCE33L0048 ENOG4108JA2 transcriptioN-repair coupling factor BCE33L0049 ENOG4108M14 stage v sporulation protein t BCE33L0051 ENOG4108IY2 MazG family BCE33L0052 ENOG41082I2 s4 domain protein BCE33L0053 ENOG4105VYY sporulation protein yabp BCE33L0056 ENOG41060GV RNA binding s1 domain protein BCE33L0059 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCE33L0060 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCE33L0063 ENOG4105C6T cysteine synthase BCE33L0064 ENOG4105CRQ synthase (Component I) BCE33L0065 ENOG4105DDQ anthranilate synthase BCE33L0066 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCE33L0067 ENOG4105EEI dihydropteroate synthase BCE33L0068 ENOG4105KRF dihydroneopterin aldolase BCE33L0069 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCE33L0071 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCE33L0075 ENOG4108Z0C Uvrb UvrC protein BCE33L0078 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCE33L0080 ENOG4105CTP PilT protein domain protein BCE33L0084 ENOG4105D7W serine acetyltransferase BCE33L0087 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCE33L0088 ENOG4105M0M Tetracycline resistance protein BCE33L0089 ENOG4105QIV RNA polymerase BCE33L0090 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCE33L0095 ENOG4107Y49 methyltransferase BCE33L0098 ENOG4105XPM ribosomal protein BCE33L0119 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCE33L0124 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCE33L0126 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCE33L0134 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCE33L0135 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BCE33L0140 ENOG4105D1F ATP-binding protein BCE33L0143 ENOG4108NMV polysaccharide deacetylase BCE33L0148 ENOG4105C8B TIGR00159 family BCE33L0149 ENOG4107U5W ybbr family BCE33L0153 ENOG4108VQT Alpha beta hydrolase fold protein BCE33L0155 ENOG4105CMG Carbohydrate kinase BCE33L0157 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BCE33L0158 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BCE33L0164 ENOG4108PSK reductase BCE33L0165 ENOG4108UMI ABC transporter, permease BCE33L0167 ENOG4105D01 (LipO)protein BCE33L0168 ENOG4105EE1 crotonyl-CoA reductase BCE33L0170 ENOG4105IQ5 FAD linked oxidase domain protein BCE33L0173 ENOG4105C2C drug resistance transporter, Bcr CflA BCE33L0176 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE33L0177 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE33L0178 ENOG4105C3U ABC transporter BCE33L0179 ENOG4108JQ7 (ABC) transporter BCE33L0183 ENOG4105U5Y Transcriptional regulator BCE33L0185 ENOG4108J59 Extracellular solute-binding protein, family 5 BCE33L0186 ENOG4108J59 Extracellular solute-binding protein, family 5 BCE33L0188 ENOG4105II7 pyrroline-5-carboxylate reductase BCE33L0189 ENOG4107XDY Nicotinamide Mononucleotide Transporter BCE33L0192 ENOG4105E0C molybdate abc transporter BCE33L0193 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCE33L0194 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCE33L0197 ENOG4105F6E Acyl-transferase BCE33L0200 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCE33L0202 ENOG4108RE7 deoxyribonuclease BCE33L0204 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCE33L0208 ENOG4105C5H ABC transporter BCE33L0209 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCE33L0211 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE33L0212 ENOG4105C3U ABC transporter BCE33L0213 ENOG4108JQ7 (ABC) transporter BCE33L0214 ENOG410667J hydrolase BCE33L0215 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCE33L0216 ENOG4105ERH Fumarylacetoacetate hydrolase BCE33L0219 ENOG4105CPF Cell wall formation (By similarity) BCE33L0220 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCE33L0223 ENOG4107ZXI Rhomboid family BCE33L0225 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCE33L0226 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCE33L0228 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCE33L0232 ENOG4105K8N protein family UPF0079, ATPase BCE33L0233 ENOG41072GX Peptidase M22 Glycoprotease BCE33L0234 ENOG410801F ribosomal-protein-alanine acetyltransferase BCE33L0235 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCE33L0236 ENOG4105C5H ABC transporter BCE33L0238 ENOG4108TYN CAAX amino terminal protease family protein BCE33L0241 ENOG4107EV6 Inherit from COG: YD repeat protein BCE33L0244 ENOG4105C7N Xanthine uracil vitamin C permease BCE33L0246 ENOG4105BZU Histidine kinase BCE33L0249 ENOG4107ZXU DSBA oxidoreductase BCE33L0258 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L0260 ENOG4105SX7 Transporter BCE33L0263 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCE33L0264 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCE33L0265 ENOG4105C83 adenylosuccinate lyase BCE33L0267 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCE33L0272 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCE33L0274 ENOG4105C12 Phosphoribosylglycinamide synthetase BCE33L0278 ENOG4105C4R Atp-dependent dna helicase BCE33L0283 ENOG4108W2Y isochorismatase BCE33L0285 ENOG4108UMI ABC transporter, permease BCE33L0286 ENOG4105D01 (LipO)protein BCE33L0289 ENOG410834F Transcriptional regulator BCE33L0290 ENOG4107I77 yiaA/B two helix domain BCE33L0294 ENOG4105CBD Diacylglycerol kinase BCE33L0295 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCE33L0296 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BCE33L0297 ENOG4108JPW Aminotransferase BCE33L0299 ENOG4105C26 Dehydrogenase BCE33L0300 ENOG4105KPY Small multidrug resistance protein BCE33L0304 ENOG4105D9N nucleoside BCE33L0305 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCE33L0307 ENOG4105BZU Histidine kinase BCE33L0308 ENOG4108W15 Protein of unknown function (DUF1456) BCE33L0311 ENOG4105DTQ mandelate racemase muconate lactonizing BCE33L0313 ENOG4105DFD Na H antiporter BCE33L0317 ENOG4105D3R alkyl hydroperoxide reductase BCE33L0318 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BCE33L0320 ENOG4107W7X Aldolase BCE33L0321 ENOG4105EHG Permease protein BCE33L0322 ENOG4105DQ5 transport system permease protein BCE33L0323 ENOG4108V5C ABC transporter BCE33L0327 ENOG4106UIA BCE33L0328 ENOG4106UIA BCE33L0334 ENOG410756H nucleotidyltransferase BCE33L0335 ENOG4105D2S major facilitator superfamily BCE33L0338 ENOG4105E5Q amino acid AbC transporter BCE33L0339 ENOG4105EAB amino acid AbC transporter BCE33L0341 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L0342 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE33L0344 ENOG4105CI1 PTS System BCE33L0351 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCE33L0354 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCE33L0358 ENOG4105C5H ABC transporter BCE33L0363 ENOG41062JF Transcriptional regulator BCE33L0367 ENOG4105DEU major facilitator superfamily BCE33L0373 ENOG4108N0M stress protein BCE33L0374 ENOG4106FN3 tellurium resistance protein BCE33L0375 ENOG4106FN3 tellurium resistance protein BCE33L0376 ENOG4107TS3 membrane protein, TerC BCE33L0377 ENOG4108TTB tellurium resistance protein BCE33L0381 ENOG4105KJF protein tyrosine phosphatase BCE33L0383 ENOG4107U9T Pfam:Ribonuclease_BN BCE33L0385 ENOG4105C59 p-type ATPase BCE33L0386 ENOG4108IPJ Membrane BCE33L0388 ENOG4105C3F Signal peptidase i BCE33L0390 ENOG4107ZTW SNARE associated Golgi BCE33L0392 ENOG410606W general stress protein BCE33L0393 ENOG4105UPD Calcium Proton BCE33L0400 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCE33L0403 ENOG4108JUB Transcriptional regulator BCE33L0405 ENOG4108IQI permease BCE33L0410 ENOG4105CSV Glutaminase BCE33L0412 ENOG4108A04 Beta-lactamase BCE33L0416 ENOG4105CKK Glycosyl transferase, family 2 BCE33L0417 ENOG4107QQG Dehydrogenase BCE33L0418 ENOG4105C3I Nad-dependent epimerase dehydratase BCE33L0421 ENOG4105F1A Pyruvate formate-lyase BCE33L0424 ENOG4105CI2 imidazolone-5-propionate hydrolase BCE33L0425 ENOG4105ECP epimerase BCE33L0429 ENOG41067AE Membrane-bound metal-dependent hydrolase BCE33L0430 ENOG4105CEN a g-specific adenine glycosylase BCE33L0431 ENOG4106BXE BCE33L0435 ENOG4105BZ1 (ABC) transporter BCE33L0436 ENOG4107NBY Membrane BCE33L0437 ENOG4105CBC glutamate synthase BCE33L0439 ENOG4108IUW ABC transporter BCE33L0443 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCE33L0444 ENOG4105G5W regulator Fur family BCE33L0451 ENOG4108JQC penicillin-binding protein 1A BCE33L0452 ENOG4107ZQN disulfide bond BCE33L0453 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCE33L0455 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCE33L0456 ENOG4105BZU Histidine kinase BCE33L0457 ENOG4105CYN Serine protein kinase BCE33L0461 ENOG4105CT1 (ABC) transporter BCE33L0462 ENOG4105CDA abc transporter atp-binding protein BCE33L0463 ENOG4105DRP amino acid AbC transporter BCE33L0464 ENOG4105DRP amino acid AbC transporter BCE33L0465 ENOG4105C94 Transporter BCE33L0468 ENOG4105DZ6 Band 7 protein BCE33L0470 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCE33L0471 ENOG4108V9W transcriptional regulatory protein BCE33L0473 ENOG4105D4T Citrate transporter BCE33L0478 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCE33L0479 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCE33L0480 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCE33L0481 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCE33L0482 ENOG4105BZ7 extracellular solute-binding protein family 1 BCE33L0483 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCE33L0484 ENOG4108STX response regulator BCE33L0485 ENOG4105US7 Histidine kinase BCE33L0490 ENOG4108MRH transcriptional regulatory protein BCE33L0492 ENOG4105C6K Malic enzyme BCE33L0494 ENOG4108UZ3 Transporter BCE33L0495 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE33L0497 ENOG4105BZU Histidine kinase BCE33L0498 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L0499 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCE33L0500 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCE33L0501 ENOG4108JB9 formate dehydrogenase BCE33L0506 ENOG4105CUB amino acid BCE33L0508 ENOG4105C59 p-type ATPase BCE33L0509 ENOG4105DAP Nicotinate phosphoribosyltransferase BCE33L0515 ENOG41073R8 VanW family BCE33L0516 ENOG4108KGH TRANSCRIPTIONal BCE33L0517 ENOG4105D9N nucleoside BCE33L0518 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCE33L0519 ENOG4105C37 (CBS) domain BCE33L0520 ENOG4108IJ0 Aspartate ammonia-lyase BCE33L0521 ENOG4105DAA L-lactate BCE33L0524 ENOG4105DUX Transporter BCE33L0525 ENOG4108MES Periplasmic binding protein BCE33L0526 ENOG4105DQ5 transport system permease protein BCE33L0527 ENOG4108IHU transport system permease protein BCE33L0528 ENOG4105E0A ABC, transporter BCE33L0529 ENOG4105DMQ Methyltransferase BCE33L0531 ENOG4105EXW epimerase dehydratase BCE33L0532 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BCE33L0534 ENOG4107T89 von Willebrand factor, type A BCE33L0535 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCE33L0536 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCE33L0539 ENOG4105BZU Histidine kinase BCE33L0540 ENOG4105D5Q Arginine ornithine antiporter BCE33L0541 ENOG4107414 GntR family transcriptional regulator BCE33L0542 ENOG4105C5Y PTS System BCE33L0543 ENOG4105CG3 alpha amylase, catalytic region BCE33L0546 ENOG4105E1K spore germination protein BCE33L0548 ENOG4105CRN Aminoglycoside phosphotransferase BCE33L0549 ENOG4105BZG amino acid carrier protein BCE33L0550 ENOG4105CDA abc transporter atp-binding protein BCE33L0551 ENOG4105CT1 (ABC) transporter BCE33L0552 ENOG4105EAD ABC transporter BCE33L0553 ENOG4105DRP amino acid AbC transporter BCE33L0554 ENOG4108IQI permease BCE33L0559 ENOG4105D29 Helix-turn-helix type 11 domain protein BCE33L0560 ENOG4105NAE bifunctional deaminase-reductase domain protein BCE33L0561 ENOG4105BZU Histidine kinase BCE33L0564 ENOG4105CHH sulfate transporter BCE33L0565 ENOG41068KF Universal stress protein BCE33L0566 ENOG4105DEF Extracellular solute-binding protein, family 5 BCE33L0568 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE33L0569 ENOG4108JQ7 (ABC) transporter BCE33L0571 ENOG4105CXY transporter BCE33L0572 ENOG41067TZ transcriptional regulator, MarR family BCE33L0573 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L0574 ENOG4105ETE Transcriptional regulator (LacI family BCE33L0575 ENOG4108RVA ribokinase BCE33L0578 ENOG4105CNN ABC, transporter BCE33L0579 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCE33L0580 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCE33L0595 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE33L0596 ENOG41069ER domain protein BCE33L0597 ENOG4105VZ8 Transcriptional regulator BCE33L0598 ENOG4107D63 BCE33L0600 ENOG4105DUX Transporter BCE33L0604 ENOG4105C85 amino acid BCE33L0605 ENOG4105C7N Xanthine uracil vitamin C permease BCE33L0608 ENOG4105MA6 gCN5-related N-acetyltransferase BCE33L0613 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCE33L0614 ENOG4105E2S oxidase) subunit II BCE33L0617 ENOG4106CAD Protein of unknown function (DUF3311) BCE33L0618 ENOG4105E1V na solute symporter BCE33L0621 ENOG4108NHD germination protein BCE33L0622 ENOG4105CE1 Ferrous iron transport protein b BCE33L0623 ENOG4105CE1 Ferrous iron transport protein b BCE33L0624 ENOG4105CE1 Ferrous iron transport protein b BCE33L0625 ENOG4105CVA phosphate BCE33L0626 ENOG4105C8U phosphate abc transporter BCE33L0627 ENOG4105E2Z phosphate ABC transporter (Permease BCE33L0631 ENOG41080XQ Signal transduction protein with cbs domains BCE33L0635 ENOG4105ETU transcriptional activator (TenA BCE33L0637 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCE33L0639 ENOG4108VEU Thiamine monophosphate synthase BCE33L0640 ENOG41080HI glycine oxidase BCE33L0643 ENOG4105D06 uba thif-type nad fad binding protein BCE33L0644 ENOG4105DWF phosphomethylpyrimidine kinase BCE33L0651 ENOG4108INS Transcriptional regulator BCE33L0654 ENOG4105C7N Xanthine uracil vitamin C permease BCE33L0656 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCE33L0663 ENOG4108B31 Spore germination protein BCE33L0667 ENOG4107Y03 Nitroreductase BCE33L0668 ENOG4105ED1 spovr family BCE33L0670 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BCE33L0671 ENOG4105XTG Pfam:DUF156 BCE33L0672 ENOG4105VFE sira family BCE33L0673 ENOG4107TPS domain protein BCE33L0674 ENOG4105VFE sira family BCE33L0675 ENOG41085GJ domain protein BCE33L0677 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCE33L0678 ENOG41087NI Sulfite exporter TauE/SafE BCE33L0680 ENOG4108KGH TRANSCRIPTIONal BCE33L0686 ENOG4105EMD TRANSCRIPTIONal BCE33L0687 ENOG4105VCP PTS System BCE33L0688 ENOG4105VZJ PTS System BCE33L0692 ENOG41069ER domain protein BCE33L0693 ENOG4107RBB ABC transporter, permease BCE33L0694 ENOG4105C19 ABC transporter BCE33L0701 ENOG4105WEF catalase BCE33L0708 ENOG4107T5V SNARE associated Golgi BCE33L0714 ENOG4105CUB amino acid BCE33L0715 ENOG4107RWR Sodium hydrogen exchanger BCE33L0717 ENOG4106KNT transcriptional regulator BCE33L0726 ENOG4108YXU transcriptional regulator AsnC family BCE33L0728 ENOG4105KPY Small multidrug resistance protein BCE33L0729 ENOG4105KPY Small multidrug resistance protein BCE33L0732 ENOG41082F9 transcriptional regulator BCE33L0733 ENOG41061H0 Monooxygenase BCE33L0734 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L0736 ENOG4105YA8 Transcriptional regulator BCE33L0737 ENOG4106A3M Cytochrome p-450 BCE33L0742 ENOG4105NF4 modulator of drug activity BCE33L0743 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCE33L0744 ENOG4105E5W Transporter BCE33L0746 ENOG4107RKG DJ-1/PfpI family BCE33L0747 ENOG4105CH6 catalase BCE33L0749 ENOG4105D5Q Arginine ornithine antiporter BCE33L0750 ENOG4105C26 Dehydrogenase BCE33L0751 ENOG4105BZ1 (ABC) transporter BCE33L0752 ENOG4105BZ1 (ABC) transporter BCE33L0754 ENOG4105DRP amino acid AbC transporter BCE33L0755 ENOG4105CDA abc transporter atp-binding protein BCE33L0758 ENOG410839P BCE33L0763 ENOG4105BZU Histidine kinase BCE33L0764 ENOG4105WH1 Two component transcriptional regulator luxr family BCE33L0773 ENOG4107FQX Alpha-acetolactate decarboxylase BCE33L0777 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE33L0778 ENOG4105D4P Coproporphyrinogen iii oxidase BCE33L0779 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L0781 ENOG4105CHH sulfate transporter BCE33L0790 ENOG4106AKK s-layer domain-containing protein BCE33L0792 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE33L0793 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE33L0796 ENOG4105CGU Enoyl-CoA hydratase BCE33L0799 ENOG4105DER m42 family BCE33L0802 ENOG4105CTU Proline racemase BCE33L0809 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE33L0811 ENOG4108JQ7 (ABC) transporter BCE33L0813 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCE33L0817 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BCE33L0826 ENOG4105D7A ATP-binding protein BCE33L0828 ENOG4105EYH Exonuclease BCE33L0830 ENOG4105C3J Cysteine desulfurase BCE33L0840 ENOG4105CDU Replicative dna helicase BCE33L0855 ENOG4107P5I polyketide synthase BCE33L0856 ENOG4108IG5 Transcriptional regulator BCE33L0858 ENOG4105CID antiterminator BCE33L0859 ENOG4105C5Y PTS System BCE33L0860 ENOG4105CS2 ec 3.2.1.21 BCE33L0862 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCE33L0868 ENOG4105CMT Dihydroxyacetone kinase BCE33L0870 ENOG4105CMT Dihydroxyacetone kinase BCE33L0872 ENOG410847I Transcriptional regulator, BadM Rrf2 family BCE33L0881 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCE33L0894 ENOG4105WN5 stage II sporulation protein BCE33L0896 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L0898 ENOG4108MJI response regulator BCE33L0899 ENOG4105BZU Histidine kinase BCE33L0900 ENOG4105BZU Histidine kinase BCE33L0904 ENOG4105K8R UPF0145 protein BCE33L0906 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L0918 ENOG4107VRP DNA repair exonuclease BCE33L0919 ENOG4106D4I domain protein BCE33L0931 ENOG4108MUZ hydrolase BCE33L0936 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCE33L0939 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCE33L0942 ENOG4105EMN RNA polymerase sigma factor BCE33L0948 ENOG4105C57 major facilitator superfamily BCE33L0949 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L0951 ENOG4105EEM helicase BCE33L0952 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE33L0957 ENOG4105K59 histidine triad (HIT) protein BCE33L0973 ENOG410905X membrane-flanked domain protein BCE33L0974 ENOG4105CKV Membrane BCE33L0982 ENOG410905X membrane-flanked domain protein BCE33L0983 ENOG4105CKV Membrane BCE33L0984 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCE33L0985 ENOG4105BZ4 penicillin-binding protein BCE33L0988 ENOG4105C1Q protoporphyrinogen oxidase BCE33L0993 ENOG4105NA0 Transcriptional regulator BCE33L0996 ENOG4105ECB domain protein BCE33L0999 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE33L1001 ENOG4105D29 Helix-turn-helix type 11 domain protein BCE33L1003 ENOG4108RQ5 Beta-lactamase domain-containing protein BCE33L1004 ENOG4105DF9 Lipoate-protein, ligase BCE33L1006 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L1009 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BCE33L1010 ENOG4107RN3 metallophosphoesterase BCE33L1011 ENOG4107TVP HD domain protein BCE33L1013 ENOG4108AEY RNA polymerase sigma factor BCE33L1014 ENOG41086D8 Transcriptional regulator BCE33L1018 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L1023 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCE33L1024 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L1028 ENOG4105ZU5 s-layer protein BCE33L1029 ENOG4107QP3 malate synthase g BCE33L1032 ENOG4105VEQ Cold shock protein BCE33L1035 ENOG4105XVF Competence transcription factor BCE33L1048 ENOG4105ERH Fumarylacetoacetate hydrolase BCE33L1053 ENOG4105CAQ asparagine synthetase BCE33L1055 ENOG4105CH6 catalase BCE33L1056 ENOG4105BZU Histidine kinase BCE33L1060 ENOG4105QNR S1 RNA binding domain protein BCE33L1061 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE33L1062 ENOG4107AYK membrAne BCE33L1063 ENOG41073B9 BCE33L1064 ENOG4108KP7 hydrolase BCE33L1066 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BCE33L1071 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCE33L1072 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCE33L1075 ENOG4105C31 Tryptophanyl-tRNA synthetase BCE33L1078 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCE33L1079 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE33L1081 ENOG4108JQ7 (ABC) transporter BCE33L1082 ENOG4105UQX Mate efflux family protein BCE33L1086 ENOG4108ZCF integral membrane protein BCE33L1088 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCE33L1090 ENOG4105DPN Oligoendopeptidase f BCE33L1092 ENOG4108Z18 K06886 hemoglobin BCE33L1093 ENOG4105MIX Adenylate cyclase BCE33L1096 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BCE33L1097 ENOG4105EMS pseudouridine synthase BCE33L1101 ENOG4105K64 Glycosyl transferase, family 2 BCE33L1105 ENOG4107TVC Glycosyl transferase, family 2 BCE33L1109 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCE33L1110 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCE33L1112 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCE33L1128 ENOG4105CK7 Sodium proline symporter BCE33L1130 ENOG4105CRQ synthase (Component I) BCE33L1131 ENOG4105DDQ anthranilate synthase BCE33L1147 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCE33L1151 ENOG4105C7S Dehydrogenase BCE33L1153 ENOG4105VZ8 Transcriptional regulator BCE33L1169 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BCE33L1171 ENOG4105DZ1 carboxypeptidase BCE33L1172 ENOG4105VFR signal peptidase BCE33L1178 ENOG4105C26 Dehydrogenase BCE33L1180 ENOG4105F38 ABC transporter, permease BCE33L1181 ENOG4105D38 putrescine abc transporter BCE33L1182 ENOG4107RUE extracellular solute-binding protein family 1 BCE33L1184 ENOG4105EYF MMPL domain protein BCE33L1186 ENOG4108YBP pseudouridine synthase BCE33L1188 ENOG4105K4I Scp-like extracellular BCE33L1189 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCE33L1190 ENOG4105CQB FAD linked oxidase domain protein BCE33L1193 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L1194 ENOG4105BZU Histidine kinase BCE33L1195 ENOG4105JXH GntR family transcriptional regulator BCE33L1199 ENOG4106A3R peptidase BCE33L1201 ENOG4108QTI )-transporter BCE33L1202 ENOG4107TS3 membrane protein, TerC BCE33L1203 ENOG4105CZN Potassium uptake protein BCE33L1204 ENOG410681C small acid-soluble spore protein BCE33L1205 ENOG4108Z7G MaoC domain protein dehydratase BCE33L1209 ENOG4105CHR reductase BCE33L1214 ENOG4105C4Y ABC transporter BCE33L1215 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCE33L1216 ENOG4107RCV ABC transporter, permease BCE33L1220 ENOG4105E98 transcriptional regulator DeoR family BCE33L1223 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCE33L1225 ENOG4105PXI polysaccharide deacetylase BCE33L1227 ENOG4105BZU Histidine kinase BCE33L1228 ENOG41090MY MarR family Transcriptional regulator BCE33L1230 ENOG4106DF1 BCE33L1231 ENOG4105BZU Histidine kinase BCE33L1233 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCE33L1234 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCE33L1241 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCE33L1242 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCE33L1243 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCE33L1244 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCE33L1245 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCE33L1246 ENOG4105CZV ABC transporter BCE33L1248 ENOG4105CJ1 ABC, transporter BCE33L1256 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCE33L1257 ENOG4105EA8 2-Nitropropane dioxygenase BCE33L1258 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCE33L1260 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCE33L1264 ENOG4105NQC Flavodoxin BCE33L1270 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BCE33L1275 ENOG4105CZN Potassium uptake protein BCE33L1276 ENOG41063Y9 BCE33L1277 ENOG4105KBJ sporulation protein ytfj BCE33L1281 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCE33L1282 ENOG4105C7K acetolactate synthase BCE33L1283 ENOG4108ZP8 Acetolactate synthase small subunit BCE33L1298 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCE33L1300 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCE33L1301 ENOG4105E0M Sulfatase BCE33L1303 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCE33L1306 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCE33L1307 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCE33L1309 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCE33L1310 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCE33L1311 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCE33L1312 ENOG4105C8J )-transporter BCE33L1316 ENOG4105DFD Na H antiporter BCE33L1320 ENOG4105ENE Histidine kinase BCE33L1321 ENOG4105WH1 Two component transcriptional regulator luxr family BCE33L1326 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCE33L1334 ENOG4105CJ3 phosphate transporter BCE33L1335 ENOG4107GRR phosphate transport regulator BCE33L1336 ENOG4105BZ4 penicillin-binding protein BCE33L1339 ENOG4105BZU Histidine kinase BCE33L1340 ENOG4105I3N Conserved Protein BCE33L1343 ENOG4105BZU Histidine kinase BCE33L1350 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE33L1351 ENOG4105DZ1 carboxypeptidase BCE33L1352 ENOG4108JIC nucleoside recognition domain protein BCE33L1354 ENOG4105FE9 pseudouridine synthase BCE33L1356 ENOG4107TWT Cytochrome c biogenesis protein BCE33L1357 ENOG4105CRE cytochrome C BCE33L1358 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L1359 ENOG4105BZU Histidine kinase BCE33L1360 ENOG4108WBT adenosyltransferase BCE33L1361 ENOG41063SB peptidase BCE33L1363 ENOG4108SAX Membrane BCE33L1366 ENOG4105C9U ATP-dependent DNA helicase RecQ BCE33L1367 ENOG4105I7S Abortive infection protein BCE33L1369 ENOG4107RGJ metallophosphoesterase BCE33L1370 ENOG4107X2D transcriptional regulator, merr family BCE33L1371 ENOG4108S6Z Negative regulator of genetic competence BCE33L1376 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCE33L1377 ENOG4105HDK L-asparaginase BCE33L1384 ENOG4105S2F BCE33L1385 ENOG41065D1 BCE33L1391 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCE33L1394 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCE33L1396 ENOG4105EAH synthase BCE33L1401 ENOG41068YB TPR repeat-containing protein BCE33L1404 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCE33L1405 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCE33L1406 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BCE33L1413 ENOG4108JYZ YitT family BCE33L1414 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCE33L1417 ENOG4105FJR Lmbe family BCE33L1418 ENOG4105CPK Glycosyl transferase (Group 1 BCE33L1425 ENOG4105DVT helicase BCE33L1429 ENOG4105CSM endonuclease III BCE33L1431 ENOG4105BZ4 penicillin-binding protein BCE33L1441 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCE33L1443 ENOG4105DVT helicase BCE33L1444 ENOG4105CTD carboxy-peptidase BCE33L1447 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCE33L1449 ENOG4105C2W permease BCE33L1450 ENOG4105DHF Membrane BCE33L1451 ENOG410890F Dynamin family BCE33L1453 ENOG4108W0I acetyltransferase BCE33L1455 ENOG4105KHC sulfurtransferase BCE33L1458 ENOG4106032 Glutathionylspermidine synthase BCE33L1465 ENOG4108SZE gCN5-related N-acetyltransferase BCE33L1469 ENOG41081VK Ribonuclease BCE33L1481 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE33L1483 ENOG4107RWR Sodium hydrogen exchanger BCE33L1484 ENOG4105CN5 Metallo-Beta-Lactamase BCE33L1485 ENOG4108Z5V transcriptional regulator, merr family BCE33L1487 ENOG4105H67 Protein of unknown function (DUF421) BCE33L1488 ENOG41080C8 DUF218 domain BCE33L1502 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCE33L1504 ENOG4107R0U MotA TolQ exbB proton channel BCE33L1505 ENOG4105ER2 Ompa motb domain protein BCE33L1506 ENOG4107YTP response regulator receiver protein BCE33L1507 ENOG4105CBS Chea signal transduction histidine kinase BCE33L1508 ENOG4105DD5 Flagellar motor switch protein BCE33L1511 ENOG4105BZU Histidine kinase BCE33L1515 ENOG4105E1Q flagellar hook-associated protein BCE33L1516 ENOG4105DTJ flagellar hook-associated protein BCE33L1517 ENOG4105DTS flagellar hook-associated BCE33L1520 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCE33L1521 ENOG4108ZC9 flagellar basal-body rod protein flgc BCE33L1522 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCE33L1523 ENOG4107U2N Flagellar M-ring protein BCE33L1524 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCE33L1530 ENOG4105BZE flagellar hook protein, FlgE BCE33L1533 ENOG4107R88 Chemotaxis protein (CheV) BCE33L1535 ENOG4105I03 Flagellin BCE33L1536 ENOG4105I03 Flagellin BCE33L1536 ENOG4105I03 Flagellin BCE33L1537 ENOG4105E4C Lytic transglycosylase catalytic BCE33L1539 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCE33L1540 ENOG4105DD5 Flagellar motor switch protein BCE33L1542 ENOG4105CN7 Flagellar biosynthetic protein FliP BCE33L1543 ENOG4105VS8 Flagellar biosynthetic protein fliq BCE33L1545 ENOG4105D00 flagellar biosynthetic protein flhB BCE33L1546 ENOG4105D7B Flagellar biosynthesis protein flha BCE33L1547 ENOG4105FZW flagellar biosynthesis regulator FlhF BCE33L1548 ENOG4105KTQ flagellar basal-body rod protein BCE33L1549 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCE33L1553 ENOG4108RZE Tetr family transcriptional regulator BCE33L1557 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCE33L1561 ENOG4105DUM transcriptional regulator, lysR family BCE33L1562 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCE33L1563 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCE33L1564 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCE33L1565 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BCE33L1571 ENOG4105CVJ phosphoglycerate mutase BCE33L1573 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BCE33L1575 ENOG4105K56 Transcriptional regulator BCE33L1577 ENOG4105CAQ asparagine synthetase BCE33L1581 ENOG4105PGM cation diffusion facilitator family transporter BCE33L1582 ENOG4105DRR Transcriptional regulator, GntR family BCE33L1583 ENOG4108UZ3 Transporter BCE33L1584 ENOG4105CKI cobalamin synthesis protein BCE33L1586 ENOG4105DFD Na H antiporter BCE33L1587 ENOG4105C9Q fumarate hydratase class II BCE33L1591 ENOG4107QJQ Mate efflux family protein BCE33L1592 ENOG4105EC3 peptidase S51, dipeptidase E BCE33L1596 ENOG4107QIV Cytochrome c biogenesis protein BCE33L1601 ENOG4106BRA Membrane BCE33L1608 ENOG4105CJ1 ABC, transporter BCE33L1612 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCE33L1614 ENOG4108IJ0 Aspartate ammonia-lyase BCE33L1615 ENOG4105C6K Malic enzyme BCE33L1621 ENOG41067QW Transcriptional regulator BCE33L1626 ENOG4105FVX BCE33L1635 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCE33L1636 ENOG4105DRS transport system, permease BCE33L1638 ENOG4108X79 transcriptional regulator BCE33L1639 ENOG4105E70 isomerase BCE33L1640 ENOG4105CE4 GlcNAc 6-P deacetylase BCE33L1642 ENOG4105DE4 1-phosphofructokinase BCE33L1644 ENOG4105CSR polyphosphate kinase 2 BCE33L1645 ENOG4105U3E Transcriptional regulator BCE33L1647 ENOG4105DXI Major Facilitator superfamily BCE33L1650 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCE33L1652 ENOG4105EU0 Major facilitator Superfamily BCE33L1653 ENOG4105C6T cysteine synthase BCE33L1657 ENOG4105C8J )-transporter BCE33L1659 ENOG4105X5K response regulator receiver protein BCE33L1660 ENOG4105H67 Protein of unknown function (DUF421) BCE33L1663 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCE33L1664 ENOG4105CHR reductase BCE33L1665 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCE33L1666 ENOG4105C7K acetolactate synthase BCE33L1670 ENOG4105C7B Threonine dehydratase BCE33L1674 ENOG4105C6X Major Facilitator BCE33L1675 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCE33L1677 ENOG4105DY9 regulatoR BCE33L1678 ENOG4105CYC Transferase BCE33L1682 ENOG4105F6J Alpha beta hydrolase fold BCE33L1688 ENOG41068WN BCE33L1693 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCE33L1696 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCE33L1697 ENOG4105C0X amino acid BCE33L1702 ENOG4107RHR regulatoR BCE33L1704 ENOG4105D9N nucleoside BCE33L1705 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCE33L1712 ENOG4107RAQ aminopeptidase BCE33L1718 ENOG4105BZ1 (ABC) transporter BCE33L1731 ENOG4108T5E Copper resistance protein BCE33L1732 ENOG4105KTB nuclear export factor GLE1 BCE33L1734 ENOG4107RT3 EamA-like transporter family BCE33L1735 ENOG4105GZI Transcriptional regulator BCE33L1736 ENOG4108Z40 Transcriptional regulator BCE33L1737 ENOG4107ZXU DSBA oxidoreductase BCE33L1738 ENOG4108TVJ Nitroreductase BCE33L1739 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCE33L1740 ENOG4106F5Q Membrane BCE33L1741 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCE33L1743 ENOG4105CKI cobalamin synthesis protein BCE33L1747 ENOG4108Z7G MaoC domain protein dehydratase BCE33L1748 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCE33L1750 ENOG4105C0Z ABC transporter BCE33L1751 ENOG4108IV0 ABC, transporter BCE33L1752 ENOG4105C32 Amino acid ABC transporter (Permease) BCE33L1754 ENOG4105SKE transcriptional Regulator LysR family BCE33L1760 ENOG4105C4M (Ubiquinol oxidase) subunit I BCE33L1761 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCE33L1762 ENOG4108JJ9 ABC, transporter BCE33L1763 ENOG4108JJ8 (ABC) transporter BCE33L1766 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCE33L1771 ENOG4105BZ1 (ABC) transporter BCE33L1772 ENOG4105EFI regulatoR BCE33L1773 ENOG4105BZU Histidine kinase BCE33L1777 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCE33L1778 ENOG4108ZJ4 polysaccharide deacetylase BCE33L1782 ENOG4105D6E homoserine dehydrogenase BCE33L1787 ENOG4108KGH TRANSCRIPTIONal BCE33L1789 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L1790 ENOG4105BZU Histidine kinase BCE33L1791 ENOG4107VMI polysaccharide deacetylase BCE33L1793 ENOG4105KT7 mgtC SapB transporter BCE33L1794 ENOG4105VRR gCN5-related N-acetyltransferase BCE33L1796 ENOG4105DUU IucA IucC family protein BCE33L1797 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L1800 ENOG4108WBH protein TIM barrel BCE33L1801 ENOG4105YWU small acid-soluble spore protein BCE33L1803 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCE33L1804 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE33L1812 ENOG4105KRN Transcriptional regulator, abrb family BCE33L1814 ENOG4105YVS arsR family transcriptional regulator BCE33L1815 ENOG4107SET aldo keto reductase BCE33L1816 ENOG4107XZQ multidrug resistance protein BCE33L1821 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L1824 ENOG4108K88 Membrane BCE33L1825 ENOG4108WPJ Ferritin-like domain BCE33L1828 ENOG4105DEN Luciferase family BCE33L1832 ENOG4107QM2 Aldo Keto reductase BCE33L1833 ENOG4105CKI cobalamin synthesis protein BCE33L1841 ENOG4105DSE periplasmic solute binding protein BCE33L1842 ENOG4105K4T epimerase BCE33L1844 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCE33L1849 ENOG4105CVJ phosphoglycerate mutase BCE33L1854 ENOG4107T5V SNARE associated Golgi BCE33L1857 ENOG4108PJD permease BCE33L1859 ENOG4108S4H thioesterase Superfamily protein BCE33L1860 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCE33L1865 ENOG4105SXS Protein of unknown function (DUF456) BCE33L1866 ENOG4105C37 (CBS) domain BCE33L1870 ENOG4108Z7R Chaperone CsaA BCE33L1873 ENOG4108ZRV stage ii sporulation protein p BCE33L1875 ENOG4108VXD carboxy-peptidase BCE33L1877 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCE33L1882 ENOG4108X4Q Hydrolase BCE33L1884 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCE33L1885 ENOG4107UWY Methyltransferase BCE33L1888 ENOG41087PP glycosyltransferase MGT family BCE33L1889 ENOG4108JYZ YitT family BCE33L1890 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCE33L1897 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCE33L1908 ENOG4105KBJ sporulation protein ytfj BCE33L1913 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCE33L1917 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BCE33L1918 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCE33L1920 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCE33L1921 ENOG4105EMN RNA polymerase sigma factor BCE33L1924 ENOG4105CNW domain protein BCE33L1926 ENOG4108V06 Glutathione peroxidase BCE33L1929 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE33L1933 ENOG4108IUE nitrate reductase beta subunit BCE33L1934 ENOG4105R3A Nitrate reductase BCE33L1936 ENOG4107V6Q Cyclic nucleotide-binding domain BCE33L1937 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCE33L1938 ENOG4105D06 uba thif-type nad fad binding protein BCE33L1939 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCE33L1940 ENOG4108ZAF Molybdopterin BCE33L1945 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCE33L1946 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCE33L1947 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCE33L1948 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BCE33L1949 ENOG4108IFG nitrite reductase, (NAD(P)H) BCE33L1950 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BCE33L1956 ENOG4105MCT stage V sporulation protein S BCE33L1964 ENOG4105C5H ABC transporter BCE33L1967 ENOG4108UUM single-stranded DNA-binding protein BCE33L1973 ENOG4107YX5 Pfam:DUF548 BCE33L1980 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCE33L1981 ENOG4105C5S asparaginyl-tRNA synthetase BCE33L1985 ENOG4105EC2 ftsk spoIIIe BCE33L1999 ENOG4105C8J )-transporter BCE33L2003 ENOG4107XGZ Hydrolase BCE33L2004 ENOG4105CY2 Citrate transporter BCE33L2005 ENOG4105C0A alcohol dehydrogenase BCE33L2008 ENOG4105KD7 acetyltransferase BCE33L2009 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCE33L2014 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCE33L2018 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCE33L2022 ENOG4107RVG penicillin-binding protein BCE33L2024 ENOG4105E9Q Acyl-transferase BCE33L2025 ENOG4108UT2 hemolysin iii BCE33L2027 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCE33L2029 ENOG4108RCR degv family BCE33L2030 ENOG4105E8R UPF0173 metal-dependent hydrolase BCE33L2031 ENOG4108KF3 Electron transport protein SCO1 SenC BCE33L2032 ENOG4107Y70 Heat shock protein BCE33L2033 ENOG4105CAQ asparagine synthetase BCE33L2036 ENOG4108MES Periplasmic binding protein BCE33L2037 ENOG4105F0I Aminotransferase BCE33L2044 ENOG4105D8X mechanosensitive ion channel BCE33L2045 ENOG4105BZU Histidine kinase BCE33L2046 ENOG4105WH1 Two component transcriptional regulator luxr family BCE33L2047 ENOG4106KNT transcriptional regulator BCE33L2053 ENOG4108YV3 Protein of unknown function (DUF2711) BCE33L2059 ENOG4108IJ8 ABC transporter BCE33L2060 ENOG4105E90 ABC transporter BCE33L2068 ENOG4105C37 (CBS) domain BCE33L2073 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE33L2076 ENOG4107S4Y M20 DapE family protein YgeY BCE33L2077 ENOG4108TSC N-acetyltransferase BCE33L2078 ENOG4108JUB Transcriptional regulator BCE33L2079 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCE33L2087 ENOG4108N23 SpoOM-related protein BCE33L2088 ENOG410841Q phosphoesterase PA-phosphatase related protein BCE33L2090 ENOG4105SZ6 Thioredoxin BCE33L2101 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCE33L2108 ENOG4105BZ4 penicillin-binding protein BCE33L2109 ENOG4105CZM Major Facilitator BCE33L2110 ENOG4105W8X HesB YadR YfhF-family protein BCE33L2112 ENOG4105DXD 2-methylcitrate dehydratase BCE33L2113 ENOG4105CR4 methylisocitrate lyase BCE33L2114 ENOG4105C1G acyl-Coa dehydrogenase BCE33L2115 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCE33L2117 ENOG4105N14 lysine exporter protein LysE YggA BCE33L2118 ENOG4105E39 Enoyl-CoA hydratase BCE33L2121 ENOG4107RFY SbcCD D subunit BCE33L2122 ENOG4105EYH Exonuclease BCE33L2126 ENOG4105FCD Major Facilitator BCE33L2127 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCE33L2128 ENOG4105E4F Isochorismate synthase BCE33L2129 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCE33L2130 ENOG4105WQI isochorismatase BCE33L2131 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L2133 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L2136 ENOG4105K70 DNA-binding protein BCE33L2140 ENOG4105BZG amino acid carrier protein BCE33L2144 ENOG4105FE9 pseudouridine synthase BCE33L2145 ENOG4105C22 threonyL-tRNA synthetase BCE33L2146 ENOG4105C19 ABC transporter BCE33L2148 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCE33L2154 ENOG4108D32 Methyltransferase BCE33L2158 ENOG41081I9 integral membrane protein BCE33L2161 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCE33L2163 ENOG4105EYF MMPL domain protein BCE33L2168 ENOG4105WCN acetyltransferase BCE33L2172 ENOG4105C1Q protoporphyrinogen oxidase BCE33L2175 ENOG41068WN BCE33L2177 ENOG4105VEQ Cold shock protein BCE33L2184 ENOG4107V2S Transcriptional regulator BCE33L2185 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCE33L2188 ENOG4105DND Transcriptional regulator BCE33L2189 ENOG4108RPX mosc domain containing protein BCE33L2192 ENOG4105BZ1 (ABC) transporter BCE33L2193 ENOG4105BZ1 (ABC) transporter BCE33L2197 ENOG4108JCI Transcriptional regulator BCE33L2203 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCE33L2206 ENOG4108KPJ rna polymerase sigma factor BCE33L2210 ENOG4105F32 YngK protein BCE33L2215 ENOG4105RD7 BadF BadG BcrA BcrD BCE33L2217 ENOG4107STF Involved in phosphonate degradation (By similarity) BCE33L2221 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCE33L2223 ENOG4105C1J atp-dependent rna helicase BCE33L2226 ENOG4108RZE Tetr family transcriptional regulator BCE33L2230 ENOG41088CC tellurite resistance protein tehB BCE33L2232 ENOG4107RA9 decarboxylase BCE33L2233 ENOG41090HR transcriptional regulator BCE33L2240 ENOG4105CIN aminoacyl-histidine dipeptidase BCE33L2243 ENOG4105EMN RNA polymerase sigma factor BCE33L2245 ENOG4107RF6 penicillin-binding protein BCE33L2246 ENOG4107RF6 penicillin-binding protein BCE33L2248 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCE33L2249 ENOG4105ETE Transcriptional regulator (LacI family BCE33L2250 ENOG4105IE8 Alpha-ketoglutarate permease BCE33L2251 ENOG4105CK5 oxidoreductase BCE33L2257 ENOG4105DH8 myo-inositol catabolism BCE33L2261 ENOG4105CGH 5'-nucleotidase BCE33L2263 ENOG4105VZ8 Transcriptional regulator BCE33L2264 ENOG4105D7V transposase BCE33L2266 ENOG4108VXD carboxy-peptidase BCE33L2269 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BCE33L2270 ENOG41067SE Tetr family transcriptional regulator BCE33L2271 ENOG4105C5H ABC transporter BCE33L2272 ENOG4105BZU Histidine kinase BCE33L2277 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BCE33L2280 ENOG4105CJ1 ABC, transporter BCE33L2282 ENOG4107Z3H Transcriptional regulator, TetR family BCE33L2285 ENOG4105C1G acyl-Coa dehydrogenase BCE33L2286 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCE33L2287 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCE33L2288 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCE33L2290 ENOG4105E39 Enoyl-CoA hydratase BCE33L2291 ENOG4107QX3 carboxylase BCE33L2292 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCE33L2296 ENOG4105WCN acetyltransferase BCE33L2297 ENOG4105DBI uridine monophosphokinase BCE33L2303 ENOG4105T9C HD domain BCE33L2305 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCE33L2316 ENOG4105FQP Beta-lactamase BCE33L2318 ENOG4107Y80 Major Facilitator superfamily BCE33L2320 ENOG41089UC methyltransferase, type 11 BCE33L2331 ENOG4105CPQ Dehydrogenase BCE33L2332 ENOG410900G Protein of unknown function (DUF421) BCE33L2336 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCE33L2337 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCE33L2339 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BCE33L2340 ENOG4105DK7 lysyl-tRNA synthetase BCE33L2354 ENOG4105D6E homoserine dehydrogenase BCE33L2357 ENOG4105ETU transcriptional activator (TenA BCE33L2364 ENOG4108TFU terminase (Small subunit) BCE33L2379 ENOG410667J hydrolase BCE33L2380 ENOG4105BZU Histidine kinase BCE33L2381 ENOG4107RF6 penicillin-binding protein BCE33L2387 ENOG4108HGU Histidine kinase BCE33L2389 ENOG4108MTT Glutamate-rich protein grpB BCE33L2390 ENOG4105CB2 alcohol dehydrogenase BCE33L2391 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCE33L2392 ENOG4105CJN penicillin-binding protein BCE33L2402 ENOG4108V4B ThiJ pfpI BCE33L2407 ENOG4105NA0 Transcriptional regulator BCE33L2410 ENOG4105E09 nadh pyrophosphatase BCE33L2412 ENOG4107Y80 Major Facilitator superfamily BCE33L2415 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCE33L2420 ENOG4107Y9U Membrane BCE33L2428 ENOG4105FCD Major Facilitator BCE33L2429 ENOG4105E09 nadh pyrophosphatase BCE33L2430 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCE33L2431 ENOG4108Z4K mutator MutT protein BCE33L2434 ENOG4108XI2 Domain of unknown function (DUF1963) BCE33L2438 ENOG4108NRW Phospholipase, patatin family BCE33L2439 ENOG4105KWG Pfam:DUF1696 BCE33L2446 ENOG4105PKS Excinuclease abc c subunit domain protein BCE33L2454 ENOG4107VFR oxidoreductase BCE33L2458 ENOG4105U0R haloacid dehalogenase-like hydrolase BCE33L2463 ENOG4108IUM Glycogen debranching enzyme BCE33L2468 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCE33L2469 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCE33L2471 ENOG4105FDR Membrane BCE33L2482 ENOG4105MSI germination protein ypeb BCE33L2489 ENOG4107Z3H Transcriptional regulator, TetR family BCE33L2495 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCE33L2497 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE33L2498 ENOG4105E98 transcriptional regulator DeoR family BCE33L2503 ENOG4107QKR Dehydrogenase BCE33L2505 ENOG4107RUY (E1 component), alpha subunit BCE33L2507 ENOG4105E1F short-chain dehydrogenase reductase BCE33L2508 ENOG4105RHY Pfam:UPF0157 BCE33L2509 ENOG4105DBI uridine monophosphokinase BCE33L2511 ENOG4108TIT dATP pyrophosphohydrolase BCE33L2515 ENOG4107SQ8 Glycine betaine BCE33L2516 ENOG4108IJ7 Glycine betaine BCE33L2521 ENOG4105E66 phosphoriboisomerase A BCE33L2522 ENOG41082BV acetyltransferase BCE33L2523 ENOG4108M1A Chitin-binding protein BCE33L2527 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE33L2528 ENOG4105MSB protein, conserved in bacteria BCE33L2530 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCE33L2535 ENOG4108Z7F N-acetyltransferase BCE33L2539 ENOG4105EEM helicase BCE33L2543 ENOG4105C9U ATP-dependent DNA helicase RecQ BCE33L2552 ENOG4108M1A Chitin-binding protein BCE33L2555 ENOG4105BZG amino acid carrier protein BCE33L2556 ENOG4105C26 Dehydrogenase BCE33L2557 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCE33L2558 ENOG4105CTU Proline racemase BCE33L2559 ENOG4105CTU Proline racemase BCE33L2560 ENOG41080HI glycine oxidase BCE33L2562 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCE33L2570 ENOG4105DCI Phosphohydrolase BCE33L2571 ENOG4107T5V SNARE associated Golgi BCE33L2574 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCE33L2575 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BCE33L2578 ENOG4105DTQ mandelate racemase muconate lactonizing BCE33L2588 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCE33L2589 ENOG4105BZU Histidine kinase BCE33L2590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L2594 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BCE33L2599 ENOG4105DPN Oligoendopeptidase f BCE33L2602 ENOG4105EPR degv family BCE33L2612 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCE33L2613 ENOG4106K7D Major facilitator family transporter BCE33L2618 ENOG4107BMA Transglycosylase associated protein BCE33L2621 ENOG41089UC methyltransferase, type 11 BCE33L2627 ENOG4105CHM Aminotransferase BCE33L2633 ENOG4105DVE abc transporter atp-binding protein BCE33L2637 ENOG4105C02 permease BCE33L2639 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCE33L2640 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCE33L2641 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCE33L2651 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCE33L2661 ENOG4107VMI polysaccharide deacetylase BCE33L2662 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BCE33L2664 ENOG4106ETB IIa component BCE33L2665 ENOG4108ZCF integral membrane protein BCE33L2666 ENOG4105E0M Sulfatase BCE33L2667 ENOG4105C5H ABC transporter BCE33L2670 ENOG4105EYF MMPL domain protein BCE33L2671 ENOG41082JN Transcriptional regulator BCE33L2677 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCE33L2684 ENOG41069ER domain protein BCE33L2686 ENOG4105CY2 Citrate transporter BCE33L2687 ENOG4105E39 Enoyl-CoA hydratase BCE33L2688 ENOG4105J5T Amp-dependent synthetase and ligase BCE33L2693 ENOG4105D4B ABC, transporter BCE33L2695 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCE33L2697 ENOG4105DKT Transcriptional regulator BCE33L2698 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BCE33L2700 ENOG41061GT Aldolase BCE33L2706 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCE33L2713 ENOG4105II7 pyrroline-5-carboxylate reductase BCE33L2715 ENOG4107258 Transcriptional regulator BCE33L2717 ENOG4105E0Y RtcB Protein BCE33L2718 ENOG4105ECK Fatty Acid Desaturase BCE33L2719 ENOG4105G6Z alkaline phosphatase BCE33L2721 ENOG4105VMP Transcriptional regulator BCE33L2723 ENOG41090T1 Membrane BCE33L2725 ENOG4108WCX response regulator BCE33L2729 ENOG4105KNA -acetyltransferase BCE33L2735 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE33L2740 ENOG4105CKK Glycosyl transferase, family 2 BCE33L2744 ENOG4105CKK Glycosyl transferase, family 2 BCE33L2746 ENOG4105C8Y Acetylornithine aminotransferase BCE33L2748 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCE33L2749 ENOG4108IY8 ABC, transporter BCE33L2752 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCE33L2759 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE33L2761 ENOG4108TVJ Nitroreductase BCE33L2762 ENOG4105FS7 Transcriptional regulator BCE33L2769 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCE33L2770 ENOG4105CMR udp-glucose 4-epimerase BCE33L2771 ENOG4105C19 ABC transporter BCE33L2777 ENOG4108XET gCN5-related N-acetyltransferase BCE33L2791 ENOG410635A Membrane BCE33L2793 ENOG4105KNA -acetyltransferase BCE33L2794 ENOG4108IQI permease BCE33L2796 ENOG4105F1N DNA alkylation repair BCE33L2802 ENOG4107RF6 penicillin-binding protein BCE33L2810 ENOG4105P4J Allophanate hydrolase, subunit 1 BCE33L2811 ENOG4107258 Transcriptional regulator BCE33L2813 ENOG4106N3A copper homeostasis protein cutc BCE33L2815 ENOG4108ZRV stage ii sporulation protein p BCE33L2816 ENOG4108ZHR arsR family transcriptional regulator BCE33L2818 ENOG4105FDT acyl-CoA dehydrogenase BCE33L2821 ENOG4105DWD nucleoside recognition domain protein BCE33L2825 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCE33L2838 ENOG4105E2A Dehydrogenase BCE33L2840 ENOG4107TXC Transcriptional regulator BCE33L2843 ENOG4105C19 ABC transporter BCE33L2845 ENOG4108IJ0 Aspartate ammonia-lyase BCE33L2846 ENOG4105HDK L-asparaginase BCE33L2847 ENOG4108IMY Transcriptional regulator BCE33L2848 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCE33L2849 ENOG4105CUB amino acid BCE33L2850 ENOG4105II7 pyrroline-5-carboxylate reductase BCE33L2851 ENOG4108NHD germination protein BCE33L2852 ENOG4108Q8B Spore germination protein BCE33L2857 ENOG4105CSV Glutaminase BCE33L2862 ENOG4107QJQ Mate efflux family protein BCE33L2863 ENOG4107QTZ amino acid BCE33L2864 ENOG4105CGH 5'-nucleotidase BCE33L2865 ENOG4105CH6 catalase BCE33L2874 ENOG4108TWJ NADH dehydrogenase subunit 5 BCE33L2875 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCE33L2880 ENOG4108VJ1 Transcriptional regulator (CarD family BCE33L2885 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCE33L2890 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BCE33L2892 ENOG4105C19 ABC transporter BCE33L2899 ENOG4105D6J arsenicaL-resistance protein BCE33L2900 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCE33L2901 ENOG41085FC arsR family transcriptional regulator BCE33L2904 ENOG4105F7F Chaperone BCE33L2906 ENOG4105CHR reductase BCE33L2921 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCE33L2922 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L2924 ENOG4105IIP Membrane BCE33L2925 ENOG4108NIW Leucine export protein LeuE BCE33L2930 ENOG4105K6H D-cysteine desulfhydrase BCE33L2934 ENOG4105VZ8 Transcriptional regulator BCE33L2937 ENOG4108NNI Beta-lactamase domain-containing protein BCE33L2938 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BCE33L2940 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCE33L2941 ENOG4105JQZ Methyltransferase BCE33L2945 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCE33L2948 ENOG4105BZU Histidine kinase BCE33L2951 ENOG4108U05 Transcriptional regulator BCE33L2952 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BCE33L2954 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCE33L2955 ENOG4105DJB Major Facilitator Superfamily BCE33L2956 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BCE33L2957 ENOG4107QR9 Iron-sulfur cluster binding protein BCE33L2959 ENOG4106P55 Transcriptional regulator BCE33L2964 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCE33L2968 ENOG4108JQ1 Dehydrogenase BCE33L2972 ENOG4108AEY RNA polymerase sigma factor BCE33L2975 ENOG41082W1 Cupin 2, conserved barrel domain protein BCE33L2976 ENOG410874W AraC family transcriptional regulator BCE33L2979 ENOG4108IBT Inherit from COG: transposase BCE33L2982 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE33L2985 ENOG4108IG5 Transcriptional regulator BCE33L2994 ENOG4108ISG Major Facilitator BCE33L2996 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCE33L2997 ENOG4105CZM Major Facilitator BCE33L3000 ENOG4105CRW Short chain fatty acid transporter BCE33L3002 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCE33L3009 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCE33L3016 ENOG4107TXC Transcriptional regulator BCE33L3019 ENOG41067QW Transcriptional regulator BCE33L3021 ENOG4108Z66 YbaK ebsC protein BCE33L3023 ENOG4105WH1 Two component transcriptional regulator luxr family BCE33L3027 ENOG4105KVH Transcriptional regulator BCE33L3028 ENOG4108RCM Nitroreductase BCE33L3032 ENOG4108PSK reductase BCE33L3034 ENOG4105CJ1 ABC, transporter BCE33L3046 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCE33L3047 ENOG4105DKQ ROK family BCE33L3048 ENOG4106UW1 Major Facilitator superfamily BCE33L3049 ENOG4106UW1 Major Facilitator superfamily BCE33L3050 ENOG4108UW5 maltose o-acetyltransferase BCE33L3052 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCE33L3053 ENOG4105C31 Tryptophanyl-tRNA synthetase BCE33L3058 ENOG4105DMQ Methyltransferase BCE33L3060 ENOG4105EV4 Multidrug resistance protein mdtH BCE33L3066 ENOG4105C37 (CBS) domain BCE33L3069 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCE33L3070 ENOG4105FAW cDP-glucose 4,6-dehydratase BCE33L3076 ENOG4105DDN Pentapeptide repeat-containing protein BCE33L3077 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCE33L3078 ENOG4105CMG Carbohydrate kinase BCE33L3079 ENOG4105C6Z Gluconate BCE33L3080 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCE33L3083 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCE33L3084 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCE33L3085 ENOG4105CIS alcohol dehydrogenase BCE33L3086 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BCE33L3090 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BCE33L3093 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L3095 ENOG4108UX3 '-nucleotidase BCE33L3096 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCE33L3097 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BCE33L3098 ENOG4105KVH Transcriptional regulator BCE33L3101 ENOG4105CV8 reductase BCE33L3102 ENOG4105F27 Major Facilitator BCE33L3105 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCE33L3106 ENOG4105C44 Serine transporter BCE33L3110 ENOG4105KVH Transcriptional regulator BCE33L3111 ENOG4108TZY GntR Family Transcriptional Regulator BCE33L3112 ENOG4105D9R oxidoreductase BCE33L3113 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCE33L3114 ENOG4105KVH Transcriptional regulator BCE33L3115 ENOG4105KVH Transcriptional regulator BCE33L3123 ENOG4105JAB phenazine biosynthesis protein, phzf family BCE33L3126 ENOG4105KNA -acetyltransferase BCE33L3128 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCE33L3129 ENOG4105KVH Transcriptional regulator BCE33L3131 ENOG4107SCK Monooxygenase BCE33L3135 ENOG4108ZJ4 polysaccharide deacetylase BCE33L3148 ENOG4105KAF membrAne BCE33L3153 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCE33L3161 ENOG4107R6D beta-lactam binding protein AmpH BCE33L3163 ENOG4105H3G oxidoreductase BCE33L3171 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCE33L3175 ENOG4105CIS alcohol dehydrogenase BCE33L3183 ENOG4108TN2 lmbE family BCE33L3185 ENOG4107R3E Citrate transporter BCE33L3188 ENOG4108MES Periplasmic binding protein BCE33L3189 ENOG4105EHG Permease protein BCE33L3190 ENOG4105DQ5 transport system permease protein BCE33L3191 ENOG4105NX3 Membrane BCE33L3192 ENOG4107ZY0 Phenazine biosynthesis-like protein BCE33L3197 ENOG4107CUJ Protein of unknown function (DUF2690) BCE33L3199 ENOG4107V2S Transcriptional regulator BCE33L3205 ENOG4105C98 muts2 protein BCE33L3206 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCE33L3207 ENOG4105DPN Oligoendopeptidase f BCE33L3208 ENOG4108A04 Beta-lactamase BCE33L3215 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCE33L3220 ENOG41082BM Transcriptional regulator, arsr family BCE33L3221 ENOG4105CIS alcohol dehydrogenase BCE33L3223 ENOG4107JM4 Tetratricopeptide repeat BCE33L3227 ENOG4105RHY Pfam:UPF0157 BCE33L3229 ENOG4105C09 Bile acid BCE33L3230 ENOG4105CQB FAD linked oxidase domain protein BCE33L3234 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCE33L3236 ENOG4105K64 Glycosyl transferase, family 2 BCE33L3237 ENOG4105E39 Enoyl-CoA hydratase BCE33L3239 ENOG4105KT7 mgtC SapB transporter BCE33L3242 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCE33L3243 ENOG41073R8 VanW family BCE33L3245 ENOG4108R1P BCE33L3248 ENOG4105VEQ Cold shock protein BCE33L3252 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCE33L3256 ENOG410904N short-chain dehydrogenase reductase BCE33L3258 ENOG4106IQC argininosuccinate lyase BCE33L3261 ENOG4108IA2 Sodium pantothenate symporter BCE33L3263 ENOG4105C26 Dehydrogenase BCE33L3264 ENOG4105CHR reductase BCE33L3265 ENOG4105EWU Squalene--hopene cyclase BCE33L3267 ENOG4105FR1 rard protein BCE33L3268 ENOG410696E Membrane BCE33L3271 ENOG4105D1F ATP-binding protein BCE33L3273 ENOG4108ZAF Molybdopterin BCE33L3274 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCE33L3275 ENOG4105D06 uba thif-type nad fad binding protein BCE33L3276 ENOG4105TMB Formate nitrite transporter BCE33L3278 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCE33L3279 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCE33L3281 ENOG4108JB9 formate dehydrogenase BCE33L3282 ENOG4105E1K spore germination protein BCE33L3294 ENOG4107QJT sodium dicarboxylate symporter BCE33L3295 ENOG4108KGH TRANSCRIPTIONal BCE33L3297 ENOG4105EMN RNA polymerase sigma factor BCE33L3300 ENOG4105CIG ABC transporter BCE33L3302 ENOG4105D9R oxidoreductase BCE33L3304 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCE33L3306 ENOG4105K4P CoA-binding domain protein BCE33L3307 ENOG4105C0H protease BCE33L3308 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L3310 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCE33L3312 ENOG4105W8X HesB YadR YfhF-family protein BCE33L3316 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCE33L3317 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCE33L3319 ENOG4105BZ1 (ABC) transporter BCE33L3320 ENOG4108I0Z Aconitate hydratase BCE33L3324 ENOG4105E5W Transporter BCE33L3326 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCE33L3330 ENOG4107F3J Amp-dependent synthetase and ligase BCE33L3331 ENOG4107ZYJ bioY protein BCE33L3332 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L3342 ENOG4107AYK membrAne BCE33L3344 ENOG4105BZU Histidine kinase BCE33L3345 ENOG4105FBA Phospholipase Carboxylesterase BCE33L3346 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCE33L3347 ENOG4105CK7 Sodium proline symporter BCE33L3348 ENOG4105CBC glutamate synthase BCE33L3349 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCE33L3350 ENOG4108VJ1 Transcriptional regulator (CarD family BCE33L3351 ENOG4108903 Formimidoylglutamase BCE33L3367 ENOG4107QIV Cytochrome c biogenesis protein BCE33L3370 ENOG4105CH2 amidohydrolase BCE33L3372 ENOG4105CJ1 ABC, transporter BCE33L3374 ENOG4107RSM transcriptional regulator BCE33L3376 ENOG41067MG lrgb family BCE33L3381 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCE33L3384 ENOG4105BZ1 (ABC) transporter BCE33L3385 ENOG4105BZ1 (ABC) transporter BCE33L3393 ENOG4105CGH 5'-nucleotidase BCE33L3396 ENOG4108SVB resolvase BCE33L3399 ENOG4105K7K Transcriptional regulator BCE33L3405 ENOG4108JJB ABC transporter BCE33L3407 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BCE33L3445 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BCE33L3462 ENOG4105C5F glutamine synthetase BCE33L3463 ENOG4105KV4 Transcriptional regulator BCE33L3464 ENOG4105CXI aluminum resistance protein BCE33L3465 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCE33L3466 ENOG4105EN6 Membrane BCE33L3467 ENOG4106F1P AAA ATPase, central domain protein BCE33L3475 ENOG41069ER domain protein BCE33L3476 ENOG4105DM4 PTS System BCE33L3477 ENOG4105DE4 1-phosphofructokinase BCE33L3478 ENOG4105E98 transcriptional regulator DeoR family BCE33L3479 ENOG4107QW4 alcohol dehydrogenase BCE33L3480 ENOG4108SJC Membrane BCE33L3482 ENOG4105C85 amino acid BCE33L3485 ENOG4105TMB Formate nitrite transporter BCE33L3486 ENOG4105K70 DNA-binding protein BCE33L3487 ENOG4105C59 p-type ATPase BCE33L3488 ENOG410681U heavy metal transport detoxification protein BCE33L3489 ENOG4105VPX protein, conserved in bacteria BCE33L3491 ENOG4105NIV Esterase BCE33L3492 ENOG4105E0A ABC, transporter BCE33L3496 ENOG4105CGK Exodeoxyribonuclease III BCE33L3498 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCE33L3499 ENOG4105D03 DNA-3-methyladenine glycosylase II BCE33L3505 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BCE33L3506 ENOG4105BZU Histidine kinase BCE33L3515 ENOG4105F0V Cell wall hydrolase BCE33L3516 ENOG4107R6R udp-galactopyranose mutase BCE33L3517 ENOG4105E0M Sulfatase BCE33L3518 ENOG410890F Dynamin family BCE33L3523 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BCE33L3524 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L3526 ENOG4108ZHR arsR family transcriptional regulator BCE33L3532 ENOG4105DQU oxidoreductase, subunit beta BCE33L3533 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCE33L3534 ENOG4108IGT Dipeptidase BCE33L3535 ENOG4105MCT stage V sporulation protein S BCE33L3536 ENOG4105D48 metallophosphoesterase BCE33L3541 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCE33L3544 ENOG4105XZV Protein of unknown function (DUF3243) BCE33L3545 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCE33L3549 ENOG4105UIB (ABC) transporter BCE33L3550 ENOG4108JQ9 ABC transporter BCE33L3551 ENOG4105DIH basic membrane BCE33L3552 ENOG4105FDP GntR family transcriptional regulator BCE33L3553 ENOG4107QZI cell division protein FtsK BCE33L3555 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCE33L3558 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCE33L3560 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCE33L3561 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCE33L3562 ENOG4105E35 Dipicolinate synthase subunit A BCE33L3564 ENOG4105C1V Peptidase, M16 BCE33L3568 ENOG4105DTN riboflavin biosynthesis protein ribF BCE33L3571 ENOG4105W7A Protein of unknown function (DUF503) BCE33L3573 ENOG4105VHM ribosomal protein BCE33L3574 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCE33L3575 ENOG4105CHV Transcription elongation factor NusA BCE33L3577 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCE33L3579 ENOG4105DZP Membrane-associated zinc metalloprotease BCE33L3580 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BCE33L3581 ENOG4105KNE Phosphatidate cytidylyltransferase BCE33L3590 ENOG4108HE4 integrase family BCE33L3592 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCE33L3593 ENOG4105C79 DNA protecting protein DprA BCE33L3594 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCE33L3597 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCE33L3602 ENOG4105VB6 UPF0109 protein BCE33L3606 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCE33L3607 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCE33L3610 ENOG4105CHR reductase BCE33L3611 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCE33L3614 ENOG4105CB5 ATP-dependent DNA helicase recG BCE33L3615 ENOG4105DP4 dak2 domain fusion protein ylov BCE33L3616 ENOG4108ZAA Alkaline-shock protein BCE33L3618 ENOG4105FJ0 thiamine BCE33L3619 ENOG4105DJV ribulose-phosphate 3-epimerase BCE33L3621 ENOG4105D9P serine threonine protein kinase BCE33L3622 ENOG4108ZF3 Phosphatase BCE33L3624 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCE33L3626 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCE33L3627 ENOG4105C25 Primosomal protein n' BCE33L3628 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCE33L3632 ENOG4105DSJ YicC domain protein BCE33L3634 ENOG4105F23 Fibronectin-binding protein BCE33L3635 ENOG4105DC7 peptidase M24 BCE33L3651 ENOG4105C34 Pseudouridine synthase BCE33L3656 ENOG4105DBK s4 domain protein BCE33L3657 ENOG41067XK integral membrane protein BCE33L3659 ENOG4105DFA alanine racemase domain protein BCE33L3660 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCE33L3661 ENOG4105WR5 sporulation protein, YlmC YmxH family BCE33L3663 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L3665 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCE33L3666 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCE33L3667 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BCE33L3669 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BCE33L3670 ENOG4105CNI cell division protein FtsW BCE33L3673 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCE33L3674 ENOG4105CJN penicillin-binding protein BCE33L3675 ENOG4105CJN penicillin-binding protein BCE33L3676 ENOG41068DC Essential cell division protein (By similarity) BCE33L3683 ENOG4105KNH Nucleic acid-binding protein BCE33L3685 ENOG41063PX domain protein BCE33L3686 ENOG4105D78 K07001 NTE family protein BCE33L3687 ENOG4105H20 Sporulation integral membrane protein YlbJ BCE33L3689 ENOG4106H78 methyltransferase BCE33L3694 ENOG4107TB6 phosphoglycerate mutase BCE33L3697 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCE33L3707 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCE33L3708 ENOG4105CNI cell division protein FtsW BCE33L3711 ENOG4108IAB Phoh family BCE33L3715 ENOG4105QA2 BCE33L3716 ENOG4105CI3 gtp-binding protein typa BCE33L3718 ENOG4105ECY inositol monophosphatase BCE33L3722 ENOG4105CXN decarboxylase BCE33L3730 ENOG4105CPP Dehydrogenase, E1 component BCE33L3732 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCE33L3733 ENOG4108X4Q Hydrolase BCE33L3735 ENOG4105CN5 Metallo-Beta-Lactamase BCE33L3736 ENOG4107ZYR domain protein BCE33L3743 ENOG4108XRC Protein of unknown function (DUF458) BCE33L3744 ENOG4107IN1 Protein of unknown function (DUF1797) BCE33L3747 ENOG4105EPM Diguanylate phosphodiesterase BCE33L3748 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCE33L3751 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCE33L3753 ENOG4105UIN BCE33L3764 ENOG4108HGU Histidine kinase BCE33L3766 ENOG4105CHM Aminotransferase BCE33L3767 ENOG4105FKQ transcriptional regulator BCE33L3768 ENOG4105EG2 ABC transporter, permease BCE33L3770 ENOG4107FKK extracellular solute-binding protein family 1 BCE33L3772 ENOG4105CG3 alpha amylase, catalytic region BCE33L3779 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BCE33L3780 ENOG4105CHU acetyl-coa acetyltransferase BCE33L3787 ENOG4105K7K Transcriptional regulator BCE33L3788 ENOG4105DTD Dehydrogenase BCE33L3792 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCE33L3799 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCE33L3800 ENOG4106TD9 Diguanylate cyclase BCE33L3804 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCE33L3807 ENOG4105CID antiterminator BCE33L3809 ENOG4105FDP GntR family transcriptional regulator BCE33L3811 ENOG4105CE4 GlcNAc 6-P deacetylase BCE33L3817 ENOG4107ZE5 PPIases accelerate the folding of proteins BCE33L3818 ENOG4105PTM secreted protein BCE33L3819 ENOG4105J7I hydrolase BCE33L3821 ENOG4105G6R Stage v sporulation protein ae BCE33L3824 ENOG4105CZ3 stage V sporulation protein ad BCE33L3825 ENOG41090VF Stage v sporulation protein ac BCE33L3828 ENOG4105C8J )-transporter BCE33L3829 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L3831 ENOG41082AN stage II sporulation protein BCE33L3832 ENOG4105DZ1 carboxypeptidase BCE33L3833 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCE33L3834 ENOG4105DVE abc transporter atp-binding protein BCE33L3841 ENOG4105D7N magnesium and cobalt transport protein CorA BCE33L3846 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE33L3848 ENOG4105I3K Ferric uptake regulator, Fur family BCE33L3849 ENOG4105MZ9 stage II sporulation protein m BCE33L3852 ENOG4105CPC Aldo Keto reductase BCE33L3854 ENOG4105RHY Pfam:UPF0157 BCE33L3858 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCE33L3860 ENOG4105ETE Transcriptional regulator (LacI family BCE33L3861 ENOG4108YM7 Gcn5-related n-acetyltransferase BCE33L3865 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCE33L3866 ENOG4108R6K riboflavin synthase, subunit alpha BCE33L3870 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BCE33L3871 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE33L3872 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCE33L3875 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCE33L3877 ENOG4105DFD Na H antiporter BCE33L3878 ENOG4105CGH 5'-nucleotidase BCE33L3889 ENOG4108IXY short-chain dehydrogenase reductase BCE33L3890 ENOG41069FQ Metallo-beta-lactamase superfamily BCE33L3891 ENOG4105II7 pyrroline-5-carboxylate reductase BCE33L3892 ENOG4105EJQ L-serine dehydratase BCE33L3898 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCE33L3899 ENOG4105D9U N-acetyltransferase BCE33L3901 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCE33L3902 ENOG4108QEG Membrane BCE33L3903 ENOG4105CDA abc transporter atp-binding protein BCE33L3904 ENOG4105E5Q amino acid AbC transporter BCE33L3905 ENOG4108HW3 (ABC) transporter BCE33L3908 ENOG4105G7B Protein of unknown function (DUF2992) BCE33L3910 ENOG4108QY0 Membrane BCE33L3912 ENOG4105C7S Dehydrogenase BCE33L3913 ENOG4105CPP Dehydrogenase, E1 component BCE33L3917 ENOG4107RDP Dehydrogenase BCE33L3919 ENOG4108JUB Transcriptional regulator BCE33L3920 ENOG4106CCJ Protein of unknown function (DUF2627) BCE33L3921 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCE33L3924 ENOG4108IBT Inherit from COG: transposase BCE33L3925 ENOG4107QQR Sporulation BCE33L3926 ENOG4105S1Z Stage IV sporulation protein B BCE33L3927 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCE33L3929 ENOG4105DX0 Hemolysin A BCE33L3931 ENOG4105CTB Polyprenyl synthetase BCE33L3936 ENOG4108ZSR alkaline shock protein BCE33L3937 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCE33L3941 ENOG410644B Stage III sporulation protein af BCE33L3943 ENOG4105KQ4 Stage iii sporulation protein ad BCE33L3944 ENOG4108CQH stage III sporulation protein AC BCE33L3945 ENOG4105KR5 Stage iii sporulation protein BCE33L3946 ENOG4105CD2 stage iii sporulation protein aa BCE33L3951 ENOG4105DC7 peptidase M24 BCE33L3954 ENOG4105CBJ Metal-dependent enzyme BCE33L3956 ENOG4107YBY Hydrolase BCE33L3962 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BCE33L3963 ENOG4105WZW rhodanese family BCE33L3968 ENOG41080TC multidrug resistance protein BCE33L3975 ENOG4105CJ1 ABC, transporter BCE33L3976 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCE33L3982 ENOG4105C0D helicase BCE33L4005 ENOG4105C3R Methionine synthase BCE33L4007 ENOG4105C28 cystathionine BCE33L4008 ENOG4105C28 cystathionine BCE33L4013 ENOG4105C5X domain protein BCE33L4014 ENOG4105DKQ ROK family BCE33L4016 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCE33L4018 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCE33L4019 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCE33L4020 ENOG4105E2Z phosphate ABC transporter (Permease BCE33L4021 ENOG4105C8U phosphate abc transporter BCE33L4022 ENOG4105PWN phosphate abc transporter BCE33L4023 ENOG4107RF6 penicillin-binding protein BCE33L4025 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE33L4029 ENOG4105N80 Ferric uptake regulator, Fur family BCE33L4031 ENOG4105FDK ABC transporter BCE33L4032 ENOG4108JYZ YitT family BCE33L4033 ENOG41069ZM Protein of unknown function (DUF2624) BCE33L4039 ENOG4105EGD dinuclear metal center protein, YbgI family BCE33L4042 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L4043 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCE33L4047 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCE33L4048 ENOG4105KG3 cytidine deaminase BCE33L4049 ENOG4107YR5 Diacylglycerol kinase BCE33L4051 ENOG4105CTJ Metal Dependent Phosphohydrolase BCE33L4052 ENOG4105C9A Phoh family BCE33L4054 ENOG41068P3 sporulation protein YqfC BCE33L4055 ENOG4105KTH gatB Yqey BCE33L4057 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCE33L4058 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCE33L4062 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BCE33L4064 ENOG4105CSA Coproporphyrinogen iii oxidase BCE33L4065 ENOG4105KVH Transcriptional regulator BCE33L4070 ENOG4105TQK DNA polymerase iii, delta' subunit BCE33L4071 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCE33L4072 ENOG4108UK2 deaminase BCE33L4074 ENOG4105KQC Competence protein BCE33L4075 ENOG4105DXX methyltransferase BCE33L4077 ENOG4108WF2 Metal Dependent Phosphohydrolase BCE33L4079 ENOG410812S Rna-binding protein BCE33L4081 ENOG4105CQW ribosome biogenesis GTPase YqeH BCE33L4082 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCE33L4084 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L4086 ENOG4105DQ6 Transposase BCE33L4090 ENOG4108TVJ Nitroreductase BCE33L4093 ENOG4105G6Z alkaline phosphatase BCE33L4095 ENOG4108MUZ hydrolase BCE33L4101 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCE33L4102 ENOG4105MIR Phenylalanine 4-monooxygenase BCE33L4104 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCE33L4112 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCE33L4113 ENOG4108HUF Transporter BCE33L4115 ENOG4108EKI Dehydrogenase BCE33L4116 ENOG4105C28 cystathionine BCE33L4122 ENOG4107XRG penicillin-binding protein BCE33L4125 ENOG4105CFP Peptidase U32 BCE33L4126 ENOG4105XYU peptidase (U32 family) BCE33L4127 ENOG4108VQJ O-methyltransferase BCE33L4128 ENOG4105HHA aminodeoxychorismate lyase BCE33L4134 ENOG4105C02 permease BCE33L4136 ENOG41060CR BCE33L4137 ENOG4105C7H Helicase, RecD TraA family BCE33L4140 ENOG4105C3J Cysteine desulfurase BCE33L4142 ENOG4105D1H recombination factor protein RarA BCE33L4143 ENOG4108VCI transcription factor, rsfa family BCE33L4144 ENOG4105CUZ uba thif-type nad fad binding protein BCE33L4146 ENOG4105CUT histidyl-tRNA synthetase BCE33L4151 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCE33L4153 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCE33L4154 ENOG41076HS cation diffusion facilitator family transporter BCE33L4155 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCE33L4157 ENOG4105CKP Polysaccharide Biosynthesis Protein BCE33L4158 ENOG4108QG2 Membrane BCE33L4160 ENOG4105VIE preprotein translocase, subunit YajC BCE33L4163 ENOG41061AI Protein of unknown function (DUF2905) BCE33L4166 ENOG4108HUF Transporter BCE33L4168 ENOG4108IPJ Membrane BCE33L4169 ENOG41082BM Transcriptional regulator, arsr family BCE33L4174 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCE33L4175 ENOG4108IYU L-aspartate oxidase BCE33L4178 ENOG4108RPX mosc domain containing protein BCE33L4179 ENOG4105CQC Prephenate dehydratase BCE33L4183 ENOG4105EWM Histidine kinase BCE33L4188 ENOG4105X36 (ribosomal) protein BCE33L4190 ENOG4105C03 ribonuclease BCE33L4193 ENOG4107QMS site-determining protein BCE33L4196 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCE33L4197 ENOG4105DFF Rod shape-determining protein mreb BCE33L4201 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCE33L4204 ENOG41068KH stage VI sporulation protein D BCE33L4206 ENOG4105D52 delta-aminolevulinic acid dehydratase BCE33L4211 ENOG4105K56 Transcriptional regulator BCE33L4215 ENOG4108IUQ atp-dependent protease BCE33L4220 ENOG4108QCI YvbH-like oligomerisation region BCE33L4231 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCE33L4232 ENOG4105M59 Phosphodiesterase, mj0936 family BCE33L4235 ENOG4108XJQ germination protein BCE33L4238 ENOG4105PFC Transcriptional regulator BCE33L4241 ENOG4105DZC cytosine deaminase BCE33L4242 ENOG4105DZC cytosine deaminase BCE33L4243 ENOG4105DEF Extracellular solute-binding protein, family 5 BCE33L4244 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCE33L4247 ENOG4108JQ7 (ABC) transporter BCE33L4248 ENOG4108HRK Histidine kinase BCE33L4249 ENOG4105DY9 regulatoR BCE33L4251 ENOG41067S9 phage shock protein C, PspC BCE33L4252 ENOG4108JCI Transcriptional regulator BCE33L4254 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCE33L4255 ENOG4108Z40 Transcriptional regulator BCE33L4256 ENOG4105RHA ABC transporter, permease BCE33L4257 ENOG4108IUX (ABC) transporter BCE33L4258 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCE33L4259 ENOG4105ER2 Ompa motb domain protein BCE33L4260 ENOG4105E14 MotA TolQ exbB proton channel BCE33L4261 ENOG4108VXD carboxy-peptidase BCE33L4263 ENOG4105E33 succinate dehydrogenase BCE33L4265 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCE33L4268 ENOG4105K63 Thioredoxin BCE33L4269 ENOG4105C10 Electron transfer flavoprotein BCE33L4270 ENOG4105BZJ Electron transfer flavoprotein BCE33L4271 ENOG41060WC Enoyl-CoA hydratase BCE33L4272 ENOG4107Z3H Transcriptional regulator, TetR family BCE33L4273 ENOG4105CEY Amp-dependent synthetase and ligase BCE33L4275 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCE33L4283 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L4285 ENOG4105DR4 Methyltransferase BCE33L4288 ENOG4105KFN sortase, SrtB family BCE33L4289 ENOG4105E0A ABC, transporter BCE33L4292 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCE33L4293 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCE33L4295 ENOG4105FE9 pseudouridine synthase BCE33L4297 ENOG4105DCG PHP domain protein BCE33L4302 ENOG4105C5S asparaginyl-tRNA synthetase BCE33L4305 ENOG4108RWN rrna methyltransferase BCE33L4310 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCE33L4311 ENOG4105CW7 secretion protein, HlyD family BCE33L4312 ENOG4108JGH Tetr family transcriptional regulator BCE33L4313 ENOG4105CN9 Peptidase m42 family protein BCE33L4317 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCE33L4318 ENOG4105C22 threonyL-tRNA synthetase BCE33L4319 ENOG4108TDW sporulation protein YtxC BCE33L4323 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCE33L4324 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCE33L4327 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BCE33L4328 ENOG4105C2M dna polymerase I BCE33L4329 ENOG4105BZU Histidine kinase BCE33L4330 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L4334 ENOG4108HMX isocitrate dehydrogenase (NADP) BCE33L4335 ENOG4105BZN citrate synthase BCE33L4337 ENOG4108REF Sporulation integral membrane protein ytvi BCE33L4338 ENOG4105FS0 cytoplasmic membrane protein BCE33L4343 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCE33L4344 ENOG4105C6K Malic enzyme BCE33L4345 ENOG4105C0B DNA polymerase III (alpha subunit) BCE33L4346 ENOG4105VV2 BCE33L4348 ENOG4105SFS phosphoesterase RecJ domain protein BCE33L4355 ENOG4105DC7 peptidase M24 BCE33L4363 ENOG41082W1 Cupin 2, conserved barrel domain protein BCE33L4366 ENOG4105VZ8 Transcriptional regulator BCE33L4370 ENOG4107YZX Universal stress protein BCE33L4378 ENOG4108JYZ YitT family BCE33L4383 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCE33L4384 ENOG4105KBJ sporulation protein ytfj BCE33L4387 ENOG4105EFZ amidohydrolase BCE33L4389 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCE33L4394 ENOG4106KR7 LysR family Transcriptional regulator BCE33L4396 ENOG4105U5Y Transcriptional regulator BCE33L4398 ENOG4105C28 cystathionine BCE33L4407 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCE33L4409 ENOG4105EMN RNA polymerase sigma factor BCE33L4412 ENOG4105F1V Acetoin utilization protein BCE33L4413 ENOG4105W87 Cbs domain BCE33L4414 ENOG4105DGU Histone deacetylase BCE33L4415 ENOG4106HB6 Alpha beta hydrolase BCE33L4417 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L4419 ENOG4107SNB ankyrin repeat protein YahD BCE33L4420 ENOG4105EP9 oxidoreductase BCE33L4427 ENOG4105ETE Transcriptional regulator (LacI family BCE33L4432 ENOG4105C88 aminopeptidase BCE33L4436 ENOG4105K7K Transcriptional regulator BCE33L4442 ENOG4108VDD TRNA binding domain protein BCE33L4448 ENOG4105C8F Beta-lactamase domain protein BCE33L4451 ENOG4108V15 phosphotransferase enzyme family BCE33L4452 ENOG4108IUM Glycogen debranching enzyme BCE33L4454 ENOG4107QSE Dipeptidase BCE33L4455 ENOG4105YW5 deoR family transcriptional regulator BCE33L4458 ENOG4105CBX hi0933 family BCE33L4465 ENOG4108VJ1 Transcriptional regulator (CarD family BCE33L4466 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCE33L4470 ENOG4108ZAF Molybdopterin BCE33L4471 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCE33L4472 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCE33L4474 ENOG4105D06 uba thif-type nad fad binding protein BCE33L4475 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCE33L4479 ENOG41085GJ domain protein BCE33L4482 ENOG4105DWV Homoserine O-trans-acetylase BCE33L4484 ENOG4108B31 Spore germination protein BCE33L4491 ENOG410605W Major Facilitator BCE33L4492 ENOG4107S91 Sodium hydrogen exchanger BCE33L4493 ENOG4105NCW Trka-c domain protein BCE33L4496 ENOG4105C19 ABC transporter BCE33L4499 ENOG4105N5T Radical SAM Protein BCE33L4501 ENOG4105DA5 (ABC) transporter BCE33L4510 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCE33L4511 ENOG4108Z0R Transferase BCE33L4512 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCE33L4513 ENOG4105BZF Glycosyl transferase (Group 1 BCE33L4515 ENOG4108RIR Molybdenum cofactor biosynthesis protein BCE33L4516 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE33L4524 ENOG4105EGD dinuclear metal center protein, YbgI family BCE33L4525 ENOG4107XGZ Hydrolase BCE33L4526 ENOG4105E98 transcriptional regulator DeoR family BCE33L4528 ENOG4105BZU Histidine kinase BCE33L4529 ENOG4105BZU Histidine kinase BCE33L4530 ENOG4107S9D Alpha beta hydrolase BCE33L4531 ENOG4107T7U Sulfatase BCE33L4533 ENOG4105D2X ABC transporter substrate-binding protein BCE33L4536 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCE33L4546 ENOG4108V2W Carbonate dehydratase BCE33L4547 ENOG4105C4M (Ubiquinol oxidase) subunit I BCE33L4548 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCE33L4557 ENOG41087YS Phage shock protein A BCE33L4563 ENOG4105BZU Histidine kinase BCE33L4564 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L4569 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCE33L4570 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCE33L4576 ENOG4107ZTW SNARE associated Golgi BCE33L4581 ENOG4105C19 ABC transporter BCE33L4582 ENOG41086D8 Transcriptional regulator BCE33L4584 ENOG4105CJ1 ABC, transporter BCE33L4586 ENOG41082BM Transcriptional regulator, arsr family BCE33L4594 ENOG4105C6Z Gluconate BCE33L4595 ENOG4105FDP GntR family transcriptional regulator BCE33L4599 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCE33L4600 ENOG4106P55 Transcriptional regulator BCE33L4602 ENOG4107Y2X deaminase BCE33L4606 ENOG4105DTQ mandelate racemase muconate lactonizing BCE33L4608 ENOG4108IPT Naphthoate synthase BCE33L4609 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCE33L4611 ENOG4105E4F Isochorismate synthase BCE33L4612 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCE33L4614 ENOG4105VEQ Cold shock protein BCE33L4620 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BCE33L4623 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCE33L4624 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCE33L4626 ENOG4105KT7 mgtC SapB transporter BCE33L4627 ENOG4107PBV potassium channel BCE33L4631 ENOG4105WG9 Conserved Protein BCE33L4633 ENOG4105CHM Aminotransferase BCE33L4634 ENOG4108ZB6 transcriptional regulator AsnC family BCE33L4635 ENOG4105C5I Dehydrogenase BCE33L4636 ENOG4108MUZ hydrolase BCE33L4638 ENOG4105C87 Aminotransferase class I and II BCE33L4641 ENOG4105Y38 Kinase-associated protein B BCE33L4643 ENOG4107R3E Citrate transporter BCE33L4646 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCE33L4647 ENOG4105KA0 thioesterase Superfamily protein BCE33L4650 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCE33L4654 ENOG41069ER domain protein BCE33L4657 ENOG4105CEP NADH dehydrogenase BCE33L4663 ENOG4105EWC Purine nucleoside phosphorylase BCE33L4666 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCE33L4672 ENOG4108JJA ABC, transporter BCE33L4673 ENOG4105C4B ABC transporter, permease BCE33L4674 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCE33L4678 ENOG41083MR nifu domain-containing protein BCE33L4681 ENOG4108W5N phosphatidylglycerophosphatase a BCE33L4683 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCE33L4685 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCE33L4688 ENOG4105CBT Fructose-1,6-bisphosphatase BCE33L4691 ENOG4105MMD transcriptional regulator BCE33L4692 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCE33L4693 ENOG41090T1 Membrane BCE33L4694 ENOG4107TXC Transcriptional regulator BCE33L4699 ENOG4105FAA peptidase M23 BCE33L4701 ENOG4105KZD Domain of unknown function (DUF1805) BCE33L4702 ENOG4107R8B 5'-nucleotidase BCE33L4703 ENOG4105DIW FeS assembly protein SUFB BCE33L4704 ENOG4108UNV SUF system FeS assembly protein, NifU family BCE33L4705 ENOG4105C9B Cysteine desulfurase BCE33L4706 ENOG4105JRK feS assembly protein SufD BCE33L4707 ENOG4105C3K feS assembly ATPase SufC BCE33L4708 ENOG4105D01 (LipO)protein BCE33L4709 ENOG4105D01 (LipO)protein BCE33L4710 ENOG4108UMI ABC transporter, permease BCE33L4717 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCE33L4731 ENOG4108W8B Beta-lactamase domain protein BCE33L4732 ENOG4105C1G acyl-Coa dehydrogenase BCE33L4733 ENOG4105CHU acetyl-coa acetyltransferase BCE33L4735 ENOG4105DZ1 carboxypeptidase BCE33L4739 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE33L4742 ENOG4108SUT Major Facilitator Superfamily BCE33L4743 ENOG4107R7I amino acid BCE33L4746 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCE33L4748 ENOG4107AYK membrAne BCE33L4751 ENOG4105BZU Histidine kinase BCE33L4752 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCE33L4753 ENOG4108TU7 Inherit from COG: (ABC) transporter BCE33L4755 ENOG4105CJ1 ABC, transporter BCE33L4760 ENOG4107ZTW SNARE associated Golgi BCE33L4762 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCE33L4763 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L4764 ENOG4105BZU Histidine kinase BCE33L4768 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L4769 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCE33L4770 ENOG4105VG1 fes assembly suf system protein BCE33L4771 ENOG4105D4Y metalloprotease BCE33L4775 ENOG4107S91 Sodium hydrogen exchanger BCE33L4776 ENOG4105NCW Trka-c domain protein BCE33L4778 ENOG4108RMU ferritin dps family protein BCE33L4781 ENOG4108URH decarboxylase BCE33L4785 ENOG4105D9N nucleoside BCE33L4786 ENOG4105D9N nucleoside BCE33L4789 ENOG4108RYK Nad-dependent epimerase dehydratase BCE33L4792 ENOG4105CV8 reductase BCE33L4793 ENOG4105F27 Major Facilitator BCE33L4794 ENOG4105KVH Transcriptional regulator BCE33L4800 ENOG4105C8Q Methyl-accepting chemotaxis BCE33L4806 ENOG4108MK9 spermidine N(1)-acetyltransferase BCE33L4807 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BCE33L4812 ENOG4108IPW abc transporter atp-binding protein BCE33L4813 ENOG4105CM4 permease protein BCE33L4818 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCE33L4820 ENOG4105XZU Preprotein translocase, subunit SecG BCE33L4821 ENOG41067MG lrgb family BCE33L4825 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BCE33L4831 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L4834 ENOG4108IBT Inherit from COG: transposase BCE33L4839 ENOG41090VF Stage v sporulation protein ac BCE33L4840 ENOG4105CZ3 stage V sporulation protein ad BCE33L4843 ENOG4108QY0 Membrane BCE33L4844 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCE33L4845 ENOG4105KRI phosphocarrier protein (HPr BCE33L4847 ENOG4105CHW UPF0052 protein BCE33L4849 ENOG4108Z4K mutator MutT protein BCE33L4851 ENOG4105C3M thioredoxin reductase BCE33L4853 ENOG4108S4C acetyltransferase BCE33L4857 ENOG41086DT Membrane protein of unknown function BCE33L4859 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCE33L4862 ENOG4107TXC Transcriptional regulator BCE33L4870 ENOG4105DUM transcriptional regulator, lysR family BCE33L4872 ENOG4108WS4 fmn reductase BCE33L4875 ENOG4105BZ1 (ABC) transporter BCE33L4877 ENOG4105CN1 protease BCE33L4878 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCE33L4879 ENOG4105CAK Cell division ATP-binding protein ftsE BCE33L4882 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BCE33L4884 ENOG4105MS2 ribosomal subunit Interface protein BCE33L4885 ENOG4105VEQ Cold shock protein BCE33L4886 ENOG41081UC Inherit from COG: Competence protein BCE33L4888 ENOG4105K4H Nlp p60 protein BCE33L4889 ENOG4105KVH Transcriptional regulator BCE33L4891 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCE33L4892 ENOG4108KGH TRANSCRIPTIONal BCE33L4893 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCE33L4894 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCE33L4895 ENOG4105ESV Glycosyl transferase, family 4 BCE33L4897 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCE33L4900 ENOG410901P UPF0249 protein BCE33L4901 ENOG4105F8D glycoside hydrolase family 4 BCE33L4902 ENOG4105VCP PTS System BCE33L4903 ENOG4105CK1 PTS System BCE33L4905 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BCE33L4907 ENOG4105VCP PTS System BCE33L4909 ENOG4105VZJ PTS System BCE33L4912 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCE33L4913 ENOG4105ECB domain protein BCE33L4914 ENOG4107RSM transcriptional regulator BCE33L4922 ENOG4105DAA L-lactate BCE33L4924 ENOG4105DAA L-lactate BCE33L4926 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCE33L4928 ENOG4105E0M Sulfatase BCE33L4933 ENOG4107R8N Glycosyl transferase, family 2 BCE33L4934 ENOG4105C94 Transporter BCE33L4935 ENOG41069ER domain protein BCE33L4940 ENOG4105KBK Zinc finger, swim domain protein BCE33L4941 ENOG4105C0D helicase BCE33L4947 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCE33L4950 ENOG4107RBB ABC transporter, permease BCE33L4951 ENOG4105C19 ABC transporter BCE33L4955 ENOG4105CXY transporter BCE33L4958 ENOG4105BZU Histidine kinase BCE33L4959 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L4960 ENOG4105CMR udp-glucose 4-epimerase BCE33L4964 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCE33L4975 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCE33L4976 ENOG4107BJW polysaccharide deacetylase BCE33L4978 ENOG4108UW5 maltose o-acetyltransferase BCE33L4982 ENOG4105FRN stage II sporulation protein BCE33L4985 ENOG4105DY9 regulatoR BCE33L4989 ENOG4106778 Protein of unknown function (DUF1146) BCE33L4990 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCE33L4991 ENOG4105C8S subunit m BCE33L4992 ENOG4105D65 subunit l BCE33L4998 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCE33L5000 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCE33L5001 ENOG4105BZU Histidine kinase BCE33L5011 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCE33L5012 ENOG41062M3 atp synthase BCE33L5017 ENOG4108YZG isomerase BCE33L5020 ENOG4108VGI doxx family BCE33L5021 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCE33L5025 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCE33L5027 ENOG4108ZXQ stage ii sporulation protein r BCE33L5028 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCE33L5029 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCE33L5032 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCE33L5033 ENOG4105CBT Fructose-1,6-bisphosphatase BCE33L5034 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCE33L5041 ENOG4105C1G acyl-Coa dehydrogenase BCE33L5042 ENOG4105C1G acyl-Coa dehydrogenase BCE33L5043 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCE33L5045 ENOG4105DF6 Fe-S oxidoreductase BCE33L5048 ENOG4105BZU Histidine kinase BCE33L5051 ENOG4105BZU Histidine kinase BCE33L5052 ENOG4105KCT ABC transporter BCE33L5053 ENOG4108M15 ABC transporter BCE33L5054 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCE33L5056 ENOG4105IIU Aminopeptidase BCE33L5060 ENOG4105EMN RNA polymerase sigma factor BCE33L5062 ENOG410684U Domain of unknown function (DUF1934) BCE33L5066 ENOG4105CYW agmatinase BCE33L5068 ENOG4105DXB Major Facilitator superfamily BCE33L5069 ENOG4107SWG transcriptional regulator MERR family BCE33L5070 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCE33L5071 ENOG4105BZ4 penicillin-binding protein BCE33L5072 ENOG4108XFG YwhD family BCE33L5073 ENOG4108Z4T Peptidase M50 BCE33L5074 ENOG41069HH 4-oxalocrotonate tautomerase BCE33L5076 ENOG4105DCI Phosphohydrolase BCE33L5077 ENOG4108MES Periplasmic binding protein BCE33L5078 ENOG4105E0A ABC, transporter BCE33L5079 ENOG4105EHG Permease protein BCE33L5080 ENOG4105DQ5 transport system permease protein BCE33L5082 ENOG4108VCI transcription factor, rsfa family BCE33L5085 ENOG4108IJ2 phosphate acetyltransferase BCE33L5088 ENOG4108VKI Cell wall hydrolase BCE33L5092 ENOG4107SVH Potassium channel protein BCE33L5094 ENOG410667J hydrolase BCE33L5095 ENOG4105VCH membrane BCE33L5097 ENOG4108TU7 Inherit from COG: (ABC) transporter BCE33L5098 ENOG4105CJ1 ABC, transporter BCE33L5099 ENOG41090WU lipolytic protein G-D-S-L family BCE33L5102 ENOG4105D6E homoserine dehydrogenase BCE33L5106 ENOG4108Y4K DNA-binding transcriptional activator BCE33L5108 ENOG4105WH1 Two component transcriptional regulator luxr family BCE33L5109 ENOG4105BZU Histidine kinase BCE33L5110 ENOG4105DWF phosphomethylpyrimidine kinase BCE33L5111 ENOG4105BZU Histidine kinase BCE33L5112 ENOG4105VCD cytoplasmic protein BCE33L5113 ENOG4105D22 carbon starvation protein BCE33L5114 ENOG4105DY9 regulatoR BCE33L5115 ENOG41079KZ Major Facilitator Superfamily BCE33L5119 ENOG4105EN6 Membrane BCE33L5120 ENOG4106YBV Methyl-accepting chemotaxis BCE33L5122 ENOG4108S4H thioesterase Superfamily protein BCE33L5124 ENOG4105JEU Glycosyl transferase, family 2 BCE33L5125 ENOG4105C5H ABC transporter BCE33L5129 ENOG4105CKK Glycosyl transferase, family 2 BCE33L5130 ENOG41067SE Tetr family transcriptional regulator BCE33L5132 ENOG4105E0X reductase BCE33L5133 ENOG4106F5Q Membrane BCE33L5137 ENOG4105DY9 regulatoR BCE33L5138 ENOG4108HRK Histidine kinase BCE33L5139 ENOG4107RGD Major Facilitator superfamily BCE33L5142 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCE33L5144 ENOG4105IW1 AmiS UreI transporter BCE33L5146 ENOG4105CMR udp-glucose 4-epimerase BCE33L5147 ENOG4108UT2 hemolysin iii BCE33L5149 ENOG4105C1J atp-dependent rna helicase BCE33L5152 ENOG4105DPN Oligoendopeptidase f BCE33L5158 ENOG4105C0H protease BCE33L5159 ENOG4105Q2H domain protein BCE33L5162 ENOG4105BZU Histidine kinase BCE33L5163 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCE33L5165 ENOG4105CDU Replicative dna helicase BCE33L5167 ENOG4105BZR domain protein BCE33L5168 ENOG4108XMW Membrane BCE33L5170 ENOG4108UUM single-stranded DNA-binding protein BCE33L5172 ENOG4105C3G gtp-binding protein BCE33L5173 ENOG4105VDK protein, conserved in bacteria BCE33L5174 ENOG4105D8X mechanosensitive ion channel BCE33L5175 ENOG4108ZDA Sporulation protein YyaC BCE33L5176 ENOG4105FA0 parb-like partition protein BCE33L5177 ENOG4107QJE Chromosome Partitioning Protein BCE33L5183 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCE33LtRNA-Leu-4 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation pE33L466_0002 ENOG4108C33 Resolvase pE33L466_0037 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) pE33L466_0042 ENOG4105D7V transposase pE33L466_0046 ENOG4105C94 Transporter pE33L466_0047 ENOG4105DQ6 Transposase pE33L466_0064 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) pE33L466_0066 ENOG4107Y80 Major Facilitator superfamily pE33L466_0074 ENOG4105MKU Transcriptional regulator pE33L466_0079 ENOG4107A6P pE33L466_0080 ENOG4107VMI polysaccharide deacetylase pE33L466_0084 ENOG4108IBT Inherit from COG: transposase pE33L466_0089 ENOG4108594 Permease of the drug metabolite transporter pE33L466_0090 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family pE33L466_0091 ENOG4105D7V transposase pE33L466_0093 ENOG4105DUX Transporter pE33L466_0096 ENOG4105F6J Alpha beta hydrolase fold pE33L466_0105 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) pE33L466_0127 ENOG4108QY0 Membrane pE33L466_0139 ENOG4105E1K spore germination protein pE33L466_0147 ENOG4105F0V Cell wall hydrolase pE33L466_0152 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) pE33L466_0153 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) pE33L466_0154 ENOG4105KVH Transcriptional regulator pE33L466_0170 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD pE33L466_0171 ENOG4107UVV polysaccharide deacetylase pE33L466_0174 ENOG4107ZTW SNARE associated Golgi pE33L466_0180 ENOG4105D7V transposase pE33L466_0183 ENOG4105D7V transposase pE33L466_0192 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) pE33L466_0194 ENOG4105DQ6 Transposase pE33L466_0196 ENOG4105EKQ RNA-directed DNA polymerase pE33L466_0212 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) pE33L466_0234 ENOG4105K4H Nlp p60 protein pE33L466_0244 ENOG4105W5Q DNA repair protein (RadC pE33L466_0246 ENOG4105RHY Pfam:UPF0157 pE33L466_0260 ENOG4108Z7R Chaperone CsaA pE33L466_0261 ENOG4107XGZ Hydrolase pE33L466_0262 ENOG4105BZ8 glutamate synthase pE33L466_0268 ENOG4108T9Y Inner membrane protein ydcZ pE33L466_0272 ENOG4105D7V transposase pE33L466_0276 ENOG4108M1A Chitin-binding protein pE33L466_0294 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) pE33L466_0295 ENOG4107QNK )-transporter pE33L466_0296 ENOG4105ETE Transcriptional regulator (LacI family pE33L466_0297 ENOG4105ETE Transcriptional regulator (LacI family pE33L466_0298 ENOG4105IE8 Alpha-ketoglutarate permease pE33L466_0299 ENOG4105CK5 oxidoreductase pE33L466_0304 ENOG4105ETE Transcriptional regulator (LacI family pE33L466_0305 ENOG4105D2N Aldolase pE33L466_0306 ENOG4105DH8 myo-inositol catabolism pE33L466_0307 ENOG4105DQ6 Transposase pE33L466_0313 ENOG4105C6E dna polymerase iii pE33L466_0316 ENOG4105CHM Aminotransferase pE33L466_0328 ENOG4105DQ6 Transposase pE33L466_0331 ENOG4108Z5V transcriptional regulator, merr family pE33L466_0334 ENOG4105D7V transposase pE33L466_0335 ENOG410780I phosphoprotein phosphatase activity pE33L466_0340 ENOG4106P37 HTH-type transcriptional regulator YjhI pE33L466_0342 ENOG4105D7K pfkb domain protein pE33L466_0343 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) pE33L466_0344 ENOG4105CHR reductase pE33L466_0346 ENOG4105ETZ PTS System pE33L466_0347 ENOG4105F3R pts system mannose fructose sorbose family iid pE33L466_0348 ENOG4108EQA pts system pE33L466_0349 ENOG4105EP8 Glycosyl Hydrolase Family 88 pE33L466_0352 ENOG4106AM8 polysaccharide lyase family 8 pE33L466_0353 ENOG4108R6W Transcriptional regulator, ARAC family pE33L466_0354 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) pE33L466_0355 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) pE33L466_0356 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase pE33L466_0362 ENOG41090MY MarR family Transcriptional regulator pE33L466_0363 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase pE33L466_0364 ENOG4107XWI flavin reductase domain protein, FMN-binding pE33L466_0365 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase pE33L466_0366 ENOG4105FBA Phospholipase Carboxylesterase pE33L466_0367 ENOG4105CSC Glucose uptake protein pE33L466_0368 ENOG4107EXU Short-chain dehydrogenase reductase Sdr pE33L466_0376 ENOG4107SDU Methyl-accepting chemotaxis pE33L466_0378 ENOG4105DQ6 Transposase pE33L466_0379 ENOG4105C8Q Methyl-accepting chemotaxis pE33L466_0380 ENOG4105D4Y metalloprotease pE33L466_0383 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme pE33L466_0386 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) pE33L466_0392 ENOG4105D7V transposase pE33L466_0399 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase pE33L466_0401 ENOG4105D7V transposase pE33L466_0404 ENOG4105D7V transposase pE33L466_0408 ENOG4108QY0 Membrane pE33L466_0415 ENOG4107TIF Phenazine biosynthesis protein, PhzF family pE33L466_0417 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) pE33L466_0441 ENOG4105CHH sulfate transporter pE33L466_0444 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA pE33L466_0445 ENOG4105D7V transposase pE33L466_0466 ENOG4105EKQ RNA-directed DNA polymerase pE33L54_0001 ENOG4107QJE Chromosome Partitioning Protein pE33L54_0021 ENOG4105KRN Transcriptional regulator, abrb family pE33L54_0026 ENOG4105DQ6 Transposase pE33L54_0031 ENOG4107TSN permease pE33L54_0036 ENOG4105DSE periplasmic solute binding protein pE33L54_0037 ENOG4105CC5 ABC transporter pE33L54_0038 ENOG4105DIK (ABC) transporter pE33L80004 ENOG4105E09 nadh pyrophosphatase pE33L9_0007 ENOG41067QW Transcriptional regulator