locus-tag class description BF28_1 ENOG4105C8B TIGR00159 family BF28_1001 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BF28_1011 ENOG4105C28 cystathionine BF28_1013 ENOG4105U5Y Transcriptional regulator BF28_1015 ENOG4106KR7 LysR family Transcriptional regulator BF28_1020 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF28_1022 ENOG4105EFZ amidohydrolase BF28_1025 ENOG4105KBJ sporulation protein ytfj BF28_1026 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BF28_1031 ENOG4108JYZ YitT family BF28_1040 ENOG4107YZX Universal stress protein BF28_1044 ENOG4105VZ8 Transcriptional regulator BF28_1046 ENOG41082W1 Cupin 2, conserved barrel domain protein BF28_1054 ENOG4105DC7 peptidase M24 BF28_1062 ENOG4105SFS phosphoesterase RecJ domain protein BF28_1064 ENOG4105VV2 BF28_1065 ENOG4105C0B DNA polymerase III (alpha subunit) BF28_1066 ENOG4105C6K Malic enzyme BF28_1067 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF28_1072 ENOG4105FS0 cytoplasmic membrane protein BF28_1073 ENOG4108REF Sporulation integral membrane protein ytvi BF28_1075 ENOG4105BZN citrate synthase BF28_1076 ENOG4108HMX isocitrate dehydrogenase (NADP) BF28_108 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BF28_1081 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_1082 ENOG4105BZU Histidine kinase BF28_1083 ENOG4105C2M dna polymerase I BF28_1084 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BF28_1087 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BF28_1089 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BF28_1093 ENOG4108TDW sporulation protein YtxC BF28_1094 ENOG4105C22 threonyL-tRNA synthetase BF28_1095 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BF28_1099 ENOG4105CN9 Peptidase m42 family protein BF28_110 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BF28_1100 ENOG4108JGH Tetr family transcriptional regulator BF28_1101 ENOG4105CW7 secretion protein, HlyD family BF28_1102 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_1107 ENOG4108RWN rrna methyltransferase BF28_111 ENOG4105KRF dihydroneopterin aldolase BF28_1110 ENOG4105C5S asparaginyl-tRNA synthetase BF28_1117 ENOG4105DCG PHP domain protein BF28_112 ENOG4105EEI dihydropteroate synthase BF28_1120 ENOG4105FE9 pseudouridine synthase BF28_1122 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BF28_1123 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BF28_1126 ENOG4105E0A ABC, transporter BF28_1127 ENOG4105KFN sortase, SrtB family BF28_113 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BF28_1130 ENOG4105DR4 Methyltransferase BF28_1133 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_114 ENOG4105DDQ anthranilate synthase BF28_1142 ENOG4105CEY Amp-dependent synthetase and ligase BF28_1143 ENOG4107Z3H Transcriptional regulator, TetR family BF28_1144 ENOG41060WC Enoyl-CoA hydratase BF28_1145 ENOG4105BZJ Electron transfer flavoprotein BF28_1146 ENOG4105C10 Electron transfer flavoprotein BF28_1147 ENOG4105K63 Thioredoxin BF28_115 ENOG4105CRQ synthase (Component I) BF28_1150 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BF28_1152 ENOG4105E33 succinate dehydrogenase BF28_1154 ENOG4108VXD carboxy-peptidase BF28_1155 ENOG4105E14 MotA TolQ exbB proton channel BF28_1156 ENOG4105ER2 Ompa motb domain protein BF28_1157 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BF28_1158 ENOG4108IUX (ABC) transporter BF28_1159 ENOG4105RHA ABC transporter, permease BF28_116 ENOG4105C6T cysteine synthase BF28_1160 ENOG4108Z40 Transcriptional regulator BF28_1161 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BF28_1163 ENOG4108JCI Transcriptional regulator BF28_1164 ENOG41067S9 phage shock protein C, PspC BF28_1166 ENOG4105DY9 regulatoR BF28_1167 ENOG4108HRK Histidine kinase BF28_1168 ENOG4108JQ7 (ABC) transporter BF28_1171 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF28_1172 ENOG4105DEF Extracellular solute-binding protein, family 5 BF28_1173 ENOG4105DZC cytosine deaminase BF28_1174 ENOG4105DZC cytosine deaminase BF28_1177 ENOG4105PFC Transcriptional regulator BF28_1180 ENOG4108XJQ germination protein BF28_1182 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BF28_1183 ENOG4105M59 Phosphodiesterase, mj0936 family BF28_1186 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF28_119 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BF28_1198 ENOG4108QCI YvbH-like oligomerisation region BF28_120 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF28_1205 ENOG4108IUQ atp-dependent protease BF28_1209 ENOG4105K56 Transcriptional regulator BF28_1214 ENOG4105D52 delta-aminolevulinic acid dehydratase BF28_1216 ENOG41068KH stage VI sporulation protein D BF28_1219 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BF28_1223 ENOG4105DFF Rod shape-determining protein mreb BF28_1224 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BF28_1227 ENOG4107QMS site-determining protein BF28_1230 ENOG4105C03 ribonuclease BF28_1232 ENOG4105X36 (ribosomal) protein BF28_1237 ENOG4105EWM Histidine kinase BF28_1241 ENOG4105CQC Prephenate dehydratase BF28_1242 ENOG4108RPX mosc domain containing protein BF28_1245 ENOG4108IYU L-aspartate oxidase BF28_1246 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BF28_125 ENOG41060GV RNA binding s1 domain protein BF28_1251 ENOG41082BM Transcriptional regulator, arsr family BF28_1252 ENOG4108IPJ Membrane BF28_1254 ENOG4108HUF Transporter BF28_1257 ENOG41061AI Protein of unknown function (DUF2905) BF28_1260 ENOG4105VIE preprotein translocase, subunit YajC BF28_1262 ENOG4108QG2 Membrane BF28_1263 ENOG4105CKP Polysaccharide Biosynthesis Protein BF28_1265 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BF28_1266 ENOG41076HS cation diffusion facilitator family transporter BF28_1267 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BF28_1269 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF28_1274 ENOG4105CUT histidyl-tRNA synthetase BF28_1276 ENOG4105CUZ uba thif-type nad fad binding protein BF28_1277 ENOG4108VCI transcription factor, rsfa family BF28_1278 ENOG4105D1H recombination factor protein RarA BF28_128 ENOG4105VYY sporulation protein yabp BF28_1280 ENOG4105C3J Cysteine desulfurase BF28_1283 ENOG4105C7H Helicase, RecD TraA family BF28_1284 ENOG41060CR BF28_1287 ENOG4105C02 permease BF28_129 ENOG41082I2 s4 domain protein BF28_1290 ENOG4105VBH UPF0297 protein BF28_1293 ENOG4105HHA aminodeoxychorismate lyase BF28_1294 ENOG4108VQJ O-methyltransferase BF28_1295 ENOG4105XYU peptidase (U32 family) BF28_1296 ENOG4105CFP Peptidase U32 BF28_1299 ENOG4107XRG penicillin-binding protein BF28_130 ENOG4108IY2 MazG family BF28_1305 ENOG4105C28 cystathionine BF28_1306 ENOG4108EKI Dehydrogenase BF28_1308 ENOG4108HUF Transporter BF28_1309 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF28_1317 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF28_1319 ENOG4105MIR Phenylalanine 4-monooxygenase BF28_132 ENOG4108M14 stage v sporulation protein t BF28_1320 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BF28_1327 ENOG4108MUZ hydrolase BF28_1329 ENOG4105G6Z alkaline phosphatase BF28_133 ENOG4108JA2 transcriptioN-repair coupling factor BF28_1332 ENOG4108TVJ Nitroreductase BF28_1336 ENOG4105DQ6 Transposase BF28_1338 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_1341 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BF28_1342 ENOG4105CQW ribosome biogenesis GTPase YqeH BF28_1344 ENOG410812S Rna-binding protein BF28_1346 ENOG4108WF2 Metal Dependent Phosphohydrolase BF28_1348 ENOG4105DXX methyltransferase BF28_1350 ENOG4105KQC Competence protein BF28_1351 ENOG4108UK2 deaminase BF28_1352 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF28_1354 ENOG4105TQK DNA polymerase iii, delta' subunit BF28_1359 ENOG4105KVH Transcriptional regulator BF28_136 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BF28_1360 ENOG4105CSA Coproporphyrinogen iii oxidase BF28_1362 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BF28_1366 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BF28_1367 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BF28_1369 ENOG4105KTH gatB Yqey BF28_1370 ENOG41068P3 sporulation protein YqfC BF28_1372 ENOG4105C9A Phoh family BF28_1373 ENOG4105CTJ Metal Dependent Phosphohydrolase BF28_1375 ENOG4107YR5 Diacylglycerol kinase BF28_1376 ENOG4105KG3 cytidine deaminase BF28_1377 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BF28_1382 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BF28_1383 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_1386 ENOG4105EGD dinuclear metal center protein, YbgI family BF28_139 ENOG4105KME endoribonuclease L-psp BF28_1391 ENOG41069ZM Protein of unknown function (DUF2624) BF28_1392 ENOG4108JYZ YitT family BF28_1393 ENOG4105FDK ABC transporter BF28_1395 ENOG4105N80 Ferric uptake regulator, Fur family BF28_140 ENOG4105DFT pur operon repressor BF28_1400 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF28_1402 ENOG4107RF6 penicillin-binding protein BF28_1403 ENOG4105PWN phosphate abc transporter BF28_1404 ENOG4105C8U phosphate abc transporter BF28_1405 ENOG4105E2Z phosphate ABC transporter (Permease BF28_1406 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BF28_1407 ENOG4108UTW Plays a role in the regulation of phosphate uptake BF28_1410 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BF28_1412 ENOG4105DKQ ROK family BF28_1414 ENOG4105C5X domain protein BF28_1418 ENOG4105C28 cystathionine BF28_1419 ENOG4105C28 cystathionine BF28_1421 ENOG4105C3R Methionine synthase BF28_143 ENOG4105W42 Veg protein BF28_144 ENOG4105XFA sporulation peptidase YabG BF28_1445 ENOG4105C0D helicase BF28_1451 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF28_1452 ENOG4105CJ1 ABC, transporter BF28_1459 ENOG41080TC multidrug resistance protein BF28_146 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BF28_1464 ENOG4105WZW rhodanese family BF28_1465 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BF28_147 ENOG4105F8V Hydrolase, tatD family BF28_1472 ENOG4107YBY Hydrolase BF28_1473 ENOG4105CBJ Metal-dependent enzyme BF28_1476 ENOG4105DC7 peptidase M24 BF28_1481 ENOG4105CD2 stage iii sporulation protein aa BF28_1482 ENOG4105KR5 Stage iii sporulation protein BF28_1483 ENOG4108CQH stage III sporulation protein AC BF28_1484 ENOG4105KQ4 Stage iii sporulation protein ad BF28_1486 ENOG410644B Stage III sporulation protein af BF28_149 ENOG4105KRN Transcriptional regulator, abrb family BF28_1491 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF28_1492 ENOG4108ZSR alkaline shock protein BF28_1497 ENOG4105CTB Polyprenyl synthetase BF28_1499 ENOG4105DX0 Hemolysin A BF28_150 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BF28_1501 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BF28_1502 ENOG4105S1Z Stage IV sporulation protein B BF28_1503 ENOG4107QQR Sporulation BF28_1504 ENOG4108IBT Inherit from COG: transposase BF28_1508 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF28_1509 ENOG4106CCJ Protein of unknown function (DUF2627) BF28_1510 ENOG4108JUB Transcriptional regulator BF28_1512 ENOG4107RDP Dehydrogenase BF28_1516 ENOG4105CPP Dehydrogenase, E1 component BF28_1517 ENOG4105C7S Dehydrogenase BF28_1519 ENOG4108QY0 Membrane BF28_152 ENOG41060K3 Methyltransferase BF28_1521 ENOG4105G7B Protein of unknown function (DUF2992) BF28_1523 ENOG4108HW3 (ABC) transporter BF28_1524 ENOG4105E5Q amino acid AbC transporter BF28_1525 ENOG4105CDA abc transporter atp-binding protein BF28_1526 ENOG4108QEG Membrane BF28_1527 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BF28_1529 ENOG4105D9U N-acetyltransferase BF28_1530 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BF28_1535 ENOG4105EJQ L-serine dehydratase BF28_1536 ENOG4105II7 pyrroline-5-carboxylate reductase BF28_1537 ENOG41069FQ Metallo-beta-lactamase superfamily BF28_1538 ENOG4108IXY short-chain dehydrogenase reductase BF28_154 ENOG4105MA4 psp1 domain protein BF28_1549 ENOG4105CGH 5'-nucleotidase BF28_155 ENOG4105FA2 dna polymerase iii BF28_1550 ENOG4105DFD Na H antiporter BF28_1552 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF28_1555 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF28_1556 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF28_1557 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BF28_1561 ENOG4108R6K riboflavin synthase, subunit alpha BF28_1562 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF28_1566 ENOG4108YM7 Gcn5-related n-acetyltransferase BF28_1567 ENOG4105ETE Transcriptional regulator (LacI family BF28_1569 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF28_157 ENOG4105CXN decarboxylase BF28_1573 ENOG4105RHY Pfam:UPF0157 BF28_1575 ENOG4105CPC Aldo Keto reductase BF28_1579 ENOG4105MZ9 stage II sporulation protein m BF28_1580 ENOG4105I3K Ferric uptake regulator, Fur family BF28_1582 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF28_1587 ENOG4105D7N magnesium and cobalt transport protein CorA BF28_1594 ENOG4105DVE abc transporter atp-binding protein BF28_1595 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF28_1596 ENOG4105DZ1 carboxypeptidase BF28_1597 ENOG41082AN stage II sporulation protein BF28_1599 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_1600 ENOG4105C8J )-transporter BF28_1604 ENOG41090VF Stage v sporulation protein ac BF28_1605 ENOG4105CZ3 stage V sporulation protein ad BF28_1607 ENOG4105G6R Stage v sporulation protein ae BF28_1609 ENOG4105J7I hydrolase BF28_1610 ENOG4105PTM secreted protein BF28_1611 ENOG4107ZE5 PPIases accelerate the folding of proteins BF28_1618 ENOG4105CE4 GlcNAc 6-P deacetylase BF28_1620 ENOG4105FDP GntR family transcriptional regulator BF28_1622 ENOG4105CID antiterminator BF28_1625 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BF28_1629 ENOG4106TD9 Diguanylate cyclase BF28_163 ENOG41067KS pro-sigma K processing BF28_1630 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF28_1638 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BF28_1642 ENOG4105DTD Dehydrogenase BF28_1643 ENOG4105K7K Transcriptional regulator BF28_1650 ENOG4105CHU acetyl-coa acetyltransferase BF28_1651 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BF28_1659 ENOG4105CG3 alpha amylase, catalytic region BF28_1661 ENOG4107FKK extracellular solute-binding protein family 1 BF28_1663 ENOG4105EG2 ABC transporter, permease BF28_1664 ENOG4105FKQ transcriptional regulator BF28_1665 ENOG4105CHM Aminotransferase BF28_1667 ENOG4108HGU Histidine kinase BF28_167 ENOG4105C6E dna polymerase iii BF28_1678 ENOG4105UIN BF28_168 ENOG4108Z6B deaminase BF28_1680 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BF28_1683 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BF28_1684 ENOG4105EPM Diguanylate phosphodiesterase BF28_1687 ENOG4107IN1 Protein of unknown function (DUF1797) BF28_1689 ENOG4108XRC Protein of unknown function (DUF458) BF28_169 ENOG4105GTG Isochorismatase BF28_1696 ENOG4107ZYR domain protein BF28_1697 ENOG4105CN5 Metallo-Beta-Lactamase BF28_1699 ENOG4108X4Q Hydrolase BF28_1700 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF28_1703 ENOG4105CPP Dehydrogenase, E1 component BF28_171 ENOG4105ZMH deoxynucleoside kinase BF28_1713 ENOG4105CXN decarboxylase BF28_1717 ENOG4105ECY inositol monophosphatase BF28_1719 ENOG4105CI3 gtp-binding protein typa BF28_1720 ENOG4105QA2 BF28_1724 ENOG4108IAB Phoh family BF28_1727 ENOG4105CNI cell division protein FtsW BF28_1728 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BF28_1738 ENOG4106UY4 Inherit from COG: Scp-like extracellular BF28_1741 ENOG4107TB6 phosphoglycerate mutase BF28_1745 ENOG4106H78 methyltransferase BF28_1746 ENOG4105H20 Sporulation integral membrane protein YlbJ BF28_1748 ENOG4105D78 K07001 NTE family protein BF28_1749 ENOG41063PX domain protein BF28_1751 ENOG4105KNH Nucleic acid-binding protein BF28_1758 ENOG41068DC Essential cell division protein (By similarity) BF28_1759 ENOG4105CJN penicillin-binding protein BF28_1760 ENOG4105CJN penicillin-binding protein BF28_1761 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF28_1764 ENOG4105CNI cell division protein FtsW BF28_1765 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BF28_1767 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BF28_1768 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BF28_1769 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BF28_1771 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_1773 ENOG4105WR5 sporulation protein, YlmC YmxH family BF28_1774 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BF28_1775 ENOG4105DFA alanine racemase domain protein BF28_1777 ENOG41067XK integral membrane protein BF28_1778 ENOG4105DBK s4 domain protein BF28_178 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BF28_1783 ENOG4105C34 Pseudouridine synthase BF28_1799 ENOG4105DC7 peptidase M24 BF28_18 ENOG4108NMV polysaccharide deacetylase BF28_1800 ENOG4105F23 Fibronectin-binding protein BF28_1802 ENOG4105DSJ YicC domain protein BF28_1806 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BF28_1807 ENOG4105C25 Primosomal protein n' BF28_1808 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF28_1810 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BF28_1812 ENOG4108ZF3 Phosphatase BF28_1813 ENOG4105D9P serine threonine protein kinase BF28_1815 ENOG4105DJV ribulose-phosphate 3-epimerase BF28_1816 ENOG4105FJ0 thiamine BF28_1818 ENOG4108ZAA Alkaline-shock protein BF28_1819 ENOG4105DP4 dak2 domain fusion protein ylov BF28_1820 ENOG4105CB5 ATP-dependent DNA helicase recG BF28_1823 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BF28_1824 ENOG4105CHR reductase BF28_1827 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BF28_1828 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BF28_1832 ENOG4105VB6 UPF0109 protein BF28_1837 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BF28_1840 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BF28_1841 ENOG4105C79 DNA protecting protein DprA BF28_1842 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF28_1844 ENOG4108HE4 integrase family BF28_1853 ENOG4105KNE Phosphatidate cytidylyltransferase BF28_1854 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BF28_1855 ENOG4105DZP Membrane-associated zinc metalloprotease BF28_1857 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF28_1859 ENOG4105CHV Transcription elongation factor NusA BF28_186 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF28_1860 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BF28_1861 ENOG4105VHM ribosomal protein BF28_1863 ENOG4105W7A Protein of unknown function (DUF503) BF28_1866 ENOG4105DTN riboflavin biosynthesis protein ribF BF28_1870 ENOG4105C1V Peptidase, M16 BF28_1872 ENOG4105E35 Dipicolinate synthase subunit A BF28_1873 ENOG4108S0H Dipicolinic acid synthetase, b subunit BF28_1874 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF28_1876 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF28_1878 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BF28_1880 ENOG4107QZI cell division protein FtsK BF28_1881 ENOG4105FDP GntR family transcriptional regulator BF28_1882 ENOG4105DIH basic membrane BF28_1883 ENOG4108JQ9 ABC transporter BF28_1884 ENOG4105UIB (ABC) transporter BF28_1888 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BF28_1889 ENOG4105XZV Protein of unknown function (DUF3243) BF28_189 ENOG410848D S4 domain protein YaaA BF28_1892 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BF28_1897 ENOG4105D48 metallophosphoesterase BF28_1898 ENOG4105MCT stage V sporulation protein S BF28_1899 ENOG4108IGT Dipeptidase BF28_190 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF28_1900 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BF28_1901 ENOG4105DQU oxidoreductase, subunit beta BF28_1907 ENOG4108ZHR arsR family transcriptional regulator BF28_1909 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_1910 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BF28_1916 ENOG410890F Dynamin family BF28_1917 ENOG4105E0M Sulfatase BF28_1918 ENOG4107R6R udp-galactopyranose mutase BF28_1919 ENOG4105F0V Cell wall hydrolase BF28_1927 ENOG4105BZU Histidine kinase BF28_1928 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BF28_1934 ENOG4105D03 DNA-3-methyladenine glycosylase II BF28_1935 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF28_1937 ENOG4105CGK Exodeoxyribonuclease III BF28_194 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF28_1941 ENOG4105E0A ABC, transporter BF28_1942 ENOG4105NIV Esterase BF28_1944 ENOG4105VPX protein, conserved in bacteria BF28_1945 ENOG410681U heavy metal transport detoxification protein BF28_1946 ENOG4105C59 p-type ATPase BF28_1947 ENOG4105K70 DNA-binding protein BF28_1948 ENOG4105TMB Formate nitrite transporter BF28_1951 ENOG4105C85 amino acid BF28_1954 ENOG4108SJC Membrane BF28_1955 ENOG4107QW4 alcohol dehydrogenase BF28_1956 ENOG4105E98 transcriptional regulator DeoR family BF28_1957 ENOG4105DE4 1-phosphofructokinase BF28_1958 ENOG4105DM4 PTS System BF28_1959 ENOG41069ER domain protein BF28_1965 ENOG4106F1P AAA ATPase, central domain protein BF28_1967 ENOG4105EN6 Membrane BF28_1968 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF28_1969 ENOG4105CXI aluminum resistance protein BF28_1970 ENOG4105KV4 Transcriptional regulator BF28_1971 ENOG4105C5F glutamine synthetase BF28_1990 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) BF28_200 ENOG4107QJE Chromosome Partitioning Protein BF28_201 ENOG4105FA0 parb-like partition protein BF28_202 ENOG4108ZDA Sporulation protein YyaC BF28_2027 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BF28_2029 ENOG4108JJB ABC transporter BF28_203 ENOG4105D8X mechanosensitive ion channel BF28_2036 ENOG4105K7K Transcriptional regulator BF28_204 ENOG4105VDK protein, conserved in bacteria BF28_2040 ENOG4108SVB resolvase BF28_2042 ENOG4105CGH 5'-nucleotidase BF28_205 ENOG4105C3G gtp-binding protein BF28_2050 ENOG4105BZ1 (ABC) transporter BF28_2051 ENOG4105BZ1 (ABC) transporter BF28_2054 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF28_2060 ENOG41067MG lrgb family BF28_2062 ENOG4107RSM transcriptional regulator BF28_2064 ENOG4105CJ1 ABC, transporter BF28_2066 ENOG4105CH2 amidohydrolase BF28_2067 ENOG4105CH2 amidohydrolase BF28_2069 ENOG4107QIV Cytochrome c biogenesis protein BF28_207 ENOG4108UUM single-stranded DNA-binding protein BF28_2083 ENOG4108903 Formimidoylglutamase BF28_2084 ENOG4108VJ1 Transcriptional regulator (CarD family BF28_2085 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BF28_2086 ENOG4105CBC glutamate synthase BF28_2087 ENOG4105CK7 Sodium proline symporter BF28_2088 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BF28_2089 ENOG4105FBA Phospholipase Carboxylesterase BF28_209 ENOG4108XMW Membrane BF28_2090 ENOG4105BZU Histidine kinase BF28_2092 ENOG4107AYK membrAne BF28_21 ENOG4105D1F ATP-binding protein BF28_210 ENOG4105BZR domain protein BF28_2101 ENOG4105CEY Amp-dependent synthetase and ligase BF28_2102 ENOG4107ZYJ bioY protein BF28_2103 ENOG4107F3J Amp-dependent synthetase and ligase BF28_2107 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF28_2109 ENOG4105E5W Transporter BF28_2115 ENOG4108I0Z Aconitate hydratase BF28_2116 ENOG4105BZ1 (ABC) transporter BF28_2118 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF28_2119 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF28_212 ENOG4105CDU Replicative dna helicase BF28_2125 ENOG4105W8X HesB YadR YfhF-family protein BF28_2127 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BF28_2129 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_2130 ENOG4105C0H protease BF28_2131 ENOG4105K4P CoA-binding domain protein BF28_2132 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF28_2134 ENOG4105D9R oxidoreductase BF28_2136 ENOG4105CIG ABC transporter BF28_2138 ENOG4105EMN RNA polymerase sigma factor BF28_2140 ENOG4108KGH TRANSCRIPTIONal BF28_2141 ENOG4107QJT sodium dicarboxylate symporter BF28_2154 ENOG4105E1K spore germination protein BF28_2155 ENOG4108JB9 formate dehydrogenase BF28_2157 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BF28_2158 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF28_2160 ENOG4105TMB Formate nitrite transporter BF28_2161 ENOG4105D06 uba thif-type nad fad binding protein BF28_2162 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF28_2163 ENOG4108ZAF Molybdopterin BF28_2165 ENOG4105D1F ATP-binding protein BF28_2168 ENOG410696E Membrane BF28_2169 ENOG4105FR1 rard protein BF28_2171 ENOG4105EWU Squalene--hopene cyclase BF28_2173 ENOG4105CHR reductase BF28_2174 ENOG4105C26 Dehydrogenase BF28_2176 ENOG4108IA2 Sodium pantothenate symporter BF28_2179 ENOG4106IQC argininosuccinate lyase BF28_218 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_2181 ENOG410904N short-chain dehydrogenase reductase BF28_2185 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BF28_2189 ENOG4105VEQ Cold shock protein BF28_219 ENOG4105BZU Histidine kinase BF28_2192 ENOG4108R1P BF28_2194 ENOG41073R8 VanW family BF28_2195 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF28_2198 ENOG4105KT7 mgtC SapB transporter BF28_2200 ENOG4105E39 Enoyl-CoA hydratase BF28_2201 ENOG4105K64 Glycosyl transferase, family 2 BF28_2203 ENOG4108UT6 Transferase hexapeptide repeat containing protein BF28_2207 ENOG4105CQB FAD linked oxidase domain protein BF28_2208 ENOG4105C09 Bile acid BF28_2214 ENOG4107JM4 Tetratricopeptide repeat BF28_2216 ENOG4105CIS alcohol dehydrogenase BF28_2217 ENOG41082BM Transcriptional regulator, arsr family BF28_222 ENOG4105Q2H domain protein BF28_2222 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF28_2228 ENOG4108A04 Beta-lactamase BF28_2229 ENOG4105DPN Oligoendopeptidase f BF28_223 ENOG4105C0H protease BF28_2230 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BF28_2231 ENOG4105C98 muts2 protein BF28_2237 ENOG4107V2S Transcriptional regulator BF28_2239 ENOG4107CUJ Protein of unknown function (DUF2690) BF28_2244 ENOG4107ZY0 Phenazine biosynthesis-like protein BF28_2245 ENOG4105NX3 Membrane BF28_2246 ENOG4105DQ5 transport system permease protein BF28_2247 ENOG4105EHG Permease protein BF28_2248 ENOG4108MES Periplasmic binding protein BF28_2251 ENOG4107R3E Citrate transporter BF28_2253 ENOG4108TN2 lmbE family BF28_2261 ENOG4105CIS alcohol dehydrogenase BF28_2264 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF28_2272 ENOG4105H3G oxidoreductase BF28_2274 ENOG4107R6D beta-lactam binding protein AmpH BF28_2284 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BF28_2289 ENOG4105KAF membrAne BF28_229 ENOG4105DPN Oligoendopeptidase f BF28_2303 ENOG4108ZJ4 polysaccharide deacetylase BF28_2307 ENOG4107SCK Monooxygenase BF28_2308 ENOG4105KVH Transcriptional regulator BF28_2309 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BF28_2311 ENOG4105KNA -acetyltransferase BF28_2314 ENOG4105JAB phenazine biosynthesis protein, phzf family BF28_232 ENOG4105C1J atp-dependent rna helicase BF28_2322 ENOG4105KVH Transcriptional regulator BF28_2323 ENOG4105KVH Transcriptional regulator BF28_2324 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BF28_2325 ENOG4105D9R oxidoreductase BF28_2326 ENOG4108TZY GntR Family Transcriptional Regulator BF28_2327 ENOG4105KVH Transcriptional regulator BF28_2333 ENOG4105C44 Serine transporter BF28_2334 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BF28_2337 ENOG4105F27 Major Facilitator BF28_2338 ENOG4105CV8 reductase BF28_234 ENOG4108UT2 hemolysin iii BF28_2341 ENOG4105KVH Transcriptional regulator BF28_2342 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BF28_2343 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF28_2344 ENOG4108UX3 '-nucleotidase BF28_2346 ENOG4105C8Q Methyl-accepting chemotaxis BF28_2349 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BF28_235 ENOG4105CMR udp-glucose 4-epimerase BF28_2353 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BF28_2354 ENOG4105CIS alcohol dehydrogenase BF28_2355 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF28_2356 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF28_2359 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF28_2360 ENOG4105C6Z Gluconate BF28_2361 ENOG4105CMG Carbohydrate kinase BF28_2362 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BF28_2363 ENOG4105XDF Protein of unknown function (DUF1272) BF28_2364 ENOG4105DDN Pentapeptide repeat-containing protein BF28_237 ENOG4105IW1 AmiS UreI transporter BF28_2370 ENOG4105FAW cDP-glucose 4,6-dehydratase BF28_2371 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BF28_2374 ENOG4105C37 (CBS) domain BF28_2380 ENOG4105EV4 Multidrug resistance protein mdtH BF28_2382 ENOG4105DMQ Methyltransferase BF28_2388 ENOG4105C31 Tryptophanyl-tRNA synthetase BF28_239 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF28_2390 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF28_2392 ENOG4108UW5 maltose o-acetyltransferase BF28_2393 ENOG4106UW1 Major Facilitator superfamily BF28_2394 ENOG4106UW1 Major Facilitator superfamily BF28_2395 ENOG4105DKQ ROK family BF28_2396 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BF28_2408 ENOG4105CJ1 ABC, transporter BF28_2410 ENOG4108PSK reductase BF28_2414 ENOG4108RCM Nitroreductase BF28_2415 ENOG4105KVH Transcriptional regulator BF28_2418 ENOG4105WH1 Two component transcriptional regulator luxr family BF28_242 ENOG4107RGD Major Facilitator superfamily BF28_2420 ENOG4108Z66 YbaK ebsC protein BF28_2422 ENOG41067QW Transcriptional regulator BF28_2425 ENOG4107TXC Transcriptional regulator BF28_243 ENOG4108HRK Histidine kinase BF28_2434 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF28_244 ENOG4105DY9 regulatoR BF28_2441 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF28_2443 ENOG4105CRW Short chain fatty acid transporter BF28_2447 ENOG4105CZM Major Facilitator BF28_2448 ENOG4107MII Sugar-specific transcriptional regulator TrmB BF28_2450 ENOG4108ISG Major Facilitator BF28_2459 ENOG4108IG5 Transcriptional regulator BF28_2461 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF28_2464 ENOG4108IBT Inherit from COG: transposase BF28_2467 ENOG410874W AraC family transcriptional regulator BF28_2468 ENOG41082W1 Cupin 2, conserved barrel domain protein BF28_247 ENOG4106F5Q Membrane BF28_2471 ENOG4108AEY RNA polymerase sigma factor BF28_2475 ENOG4108JQ1 Dehydrogenase BF28_2478 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF28_248 ENOG4105E0X reductase BF28_2483 ENOG4106P55 Transcriptional regulator BF28_2485 ENOG4107QR9 Iron-sulfur cluster binding protein BF28_2486 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BF28_2487 ENOG4105DJB Major Facilitator Superfamily BF28_2488 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF28_2490 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BF28_2491 ENOG4108U05 Transcriptional regulator BF28_2494 ENOG4105BZU Histidine kinase BF28_2497 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BF28_250 ENOG41067SE Tetr family transcriptional regulator BF28_2501 ENOG4105JQZ Methyltransferase BF28_2502 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF28_2504 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF28_2505 ENOG4108NNI Beta-lactamase domain-containing protein BF28_2508 ENOG4105VZ8 Transcriptional regulator BF28_251 ENOG4105CKK Glycosyl transferase, family 2 BF28_2512 ENOG4105K6H D-cysteine desulfhydrase BF28_2517 ENOG4108NIW Leucine export protein LeuE BF28_2519 ENOG4105IIP Membrane BF28_2521 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_2522 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BF28_2537 ENOG4105CHR reductase BF28_2539 ENOG4105F7F Chaperone BF28_2543 ENOG41085FC arsR family transcriptional regulator BF28_2544 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BF28_2545 ENOG4105D6J arsenicaL-resistance protein BF28_255 ENOG4105C5H ABC transporter BF28_2552 ENOG4105C19 ABC transporter BF28_2554 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BF28_2559 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF28_256 ENOG4105JEU Glycosyl transferase, family 2 BF28_2564 ENOG4108VJ1 Transcriptional regulator (CarD family BF28_2569 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BF28_2570 ENOG4108TWJ NADH dehydrogenase subunit 5 BF28_2579 ENOG4105CH6 catalase BF28_258 ENOG4108S4H thioesterase Superfamily protein BF28_2580 ENOG4105CGH 5'-nucleotidase BF28_2581 ENOG4107QTZ amino acid BF28_2582 ENOG4107QJQ Mate efflux family protein BF28_2588 ENOG4105CSV Glutaminase BF28_2592 ENOG4108Q8B Spore germination protein BF28_2593 ENOG4108NHD germination protein BF28_2594 ENOG4105II7 pyrroline-5-carboxylate reductase BF28_2595 ENOG4105CUB amino acid BF28_2596 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BF28_2597 ENOG4105DQ6 Transposase BF28_2598 ENOG4108IMY Transcriptional regulator BF28_2599 ENOG4105HDK L-asparaginase BF28_26 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BF28_260 ENOG4106YBV Methyl-accepting chemotaxis BF28_2600 ENOG4108IJ0 Aspartate ammonia-lyase BF28_2602 ENOG4105C19 ABC transporter BF28_2605 ENOG4107TXC Transcriptional regulator BF28_2607 ENOG4105E2A Dehydrogenase BF28_261 ENOG4105EN6 Membrane BF28_2622 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BF28_2627 ENOG4105DWD nucleoside recognition domain protein BF28_2631 ENOG4105FDT acyl-CoA dehydrogenase BF28_2633 ENOG4108ZHR arsR family transcriptional regulator BF28_2634 ENOG4108ZRV stage ii sporulation protein p BF28_2636 ENOG4106N3A copper homeostasis protein cutc BF28_2638 ENOG4107258 Transcriptional regulator BF28_2639 ENOG4105P4J Allophanate hydrolase, subunit 1 BF28_2647 ENOG4107RF6 penicillin-binding protein BF28_265 ENOG41079KZ Major Facilitator Superfamily BF28_2653 ENOG4105F1N DNA alkylation repair BF28_2655 ENOG4108IQI permease BF28_2656 ENOG4105KNA -acetyltransferase BF28_2657 ENOG410635A Membrane BF28_266 ENOG4105DY9 regulatoR BF28_267 ENOG4105D22 carbon starvation protein BF28_2672 ENOG4108XET gCN5-related N-acetyltransferase BF28_2678 ENOG4105C19 ABC transporter BF28_2679 ENOG4105CMR udp-glucose 4-epimerase BF28_268 ENOG4105VCD cytoplasmic protein BF28_2680 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF28_2687 ENOG4105FS7 Transcriptional regulator BF28_2688 ENOG4108TVJ Nitroreductase BF28_269 ENOG4105BZU Histidine kinase BF28_2690 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF28_2699 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BF28_27 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF28_270 ENOG4105DWF phosphomethylpyrimidine kinase BF28_2702 ENOG4108IY8 ABC, transporter BF28_2703 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF28_2705 ENOG4105C8Y Acetylornithine aminotransferase BF28_2707 ENOG4105CKK Glycosyl transferase, family 2 BF28_271 ENOG4105BZU Histidine kinase BF28_2711 ENOG4105CKK Glycosyl transferase, family 2 BF28_2716 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF28_272 ENOG4105WH1 Two component transcriptional regulator luxr family BF28_2722 ENOG4105KNA -acetyltransferase BF28_2726 ENOG4108WCX response regulator BF28_2728 ENOG41090T1 Membrane BF28_2731 ENOG4105VMP Transcriptional regulator BF28_2733 ENOG4105G6Z alkaline phosphatase BF28_2734 ENOG4105ECK Fatty Acid Desaturase BF28_2735 ENOG4105E0Y RtcB Protein BF28_2737 ENOG4107258 Transcriptional regulator BF28_2739 ENOG4105II7 pyrroline-5-carboxylate reductase BF28_274 ENOG4108Y4K DNA-binding transcriptional activator BF28_2746 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BF28_2752 ENOG41061GT Aldolase BF28_2754 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BF28_2755 ENOG4105DKT Transcriptional regulator BF28_2757 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BF28_2759 ENOG4105D4B ABC, transporter BF28_2765 ENOG4105J5T Amp-dependent synthetase and ligase BF28_2766 ENOG4105E39 Enoyl-CoA hydratase BF28_2767 ENOG4105CY2 Citrate transporter BF28_2769 ENOG41069ER domain protein BF28_2776 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BF28_278 ENOG4105D6E homoserine dehydrogenase BF28_2782 ENOG41082JN Transcriptional regulator BF28_2783 ENOG4105EYF MMPL domain protein BF28_2786 ENOG4105C5H ABC transporter BF28_2787 ENOG4105E0M Sulfatase BF28_2788 ENOG4108ZCF integral membrane protein BF28_2789 ENOG4106ETB IIa component BF28_2791 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BF28_2792 ENOG4107VMI polysaccharide deacetylase BF28_2802 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BF28_281 ENOG41090WU lipolytic protein G-D-S-L family BF28_2812 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BF28_2813 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BF28_2814 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BF28_2816 ENOG4105C02 permease BF28_282 ENOG4105CJ1 ABC, transporter BF28_2826 ENOG4105DVE abc transporter atp-binding protein BF28_283 ENOG4108TU7 Inherit from COG: (ABC) transporter BF28_2832 ENOG4105CHM Aminotransferase BF28_2839 ENOG41089UC methyltransferase, type 11 BF28_2842 ENOG4107BMA Transglycosylase associated protein BF28_2846 ENOG4106K7D Major facilitator family transporter BF28_2847 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF28_285 ENOG4105VCH membrane BF28_2858 ENOG4105EPR degv family BF28_286 ENOG410667J hydrolase BF28_2861 ENOG4105DPN Oligoendopeptidase f BF28_2866 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BF28_2870 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_2871 ENOG4105BZU Histidine kinase BF28_2872 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BF28_288 ENOG4107SVH Potassium channel protein BF28_2880 ENOG4105DTQ mandelate racemase muconate lactonizing BF28_2883 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BF28_2884 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF28_2887 ENOG4107T5V SNARE associated Golgi BF28_2888 ENOG4105DCI Phosphohydrolase BF28_2896 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BF28_2898 ENOG41080HI glycine oxidase BF28_2899 ENOG4105CTU Proline racemase BF28_2900 ENOG4105CTU Proline racemase BF28_2901 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF28_2902 ENOG4105C26 Dehydrogenase BF28_2903 ENOG4105BZG amino acid carrier protein BF28_2906 ENOG4108M1A Chitin-binding protein BF28_2914 ENOG4105C9U ATP-dependent DNA helicase RecQ BF28_2918 ENOG4105EEM helicase BF28_292 ENOG4108VKI Cell wall hydrolase BF28_2922 ENOG4108Z7F N-acetyltransferase BF28_2927 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF28_2929 ENOG4105MSB protein, conserved in bacteria BF28_2930 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF28_2934 ENOG4108M1A Chitin-binding protein BF28_2935 ENOG41082BV acetyltransferase BF28_2936 ENOG4105E66 phosphoriboisomerase A BF28_2941 ENOG4108IJ7 Glycine betaine BF28_2942 ENOG4107SQ8 Glycine betaine BF28_2947 ENOG4108TIT dATP pyrophosphohydrolase BF28_2949 ENOG4105DBI uridine monophosphokinase BF28_295 ENOG4108IJ2 phosphate acetyltransferase BF28_2950 ENOG4105RHY Pfam:UPF0157 BF28_2951 ENOG4105E1F short-chain dehydrogenase reductase BF28_2953 ENOG4107RUY (E1 component), alpha subunit BF28_2955 ENOG4107QKR Dehydrogenase BF28_2960 ENOG4105E98 transcriptional regulator DeoR family BF28_2961 ENOG4108MK9 spermidine N(1)-acetyltransferase BF28_2964 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BF28_2970 ENOG4107Z3H Transcriptional regulator, TetR family BF28_2977 ENOG4105MSI germination protein ypeb BF28_298 ENOG4108VCI transcription factor, rsfa family BF28_2988 ENOG4105FDR Membrane BF28_2990 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF28_2991 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BF28_2997 ENOG4108IUM Glycogen debranching enzyme BF28_300 ENOG4105DQ5 transport system permease protein BF28_3003 ENOG4105PAD Hydrolase BF28_3008 ENOG4107VFR oxidoreductase BF28_301 ENOG4105EHG Permease protein BF28_3016 ENOG4105PKS Excinuclease abc c subunit domain protein BF28_302 ENOG4105E0A ABC, transporter BF28_3023 ENOG4105KWG Pfam:DUF1696 BF28_3024 ENOG4108NRW Phospholipase, patatin family BF28_3028 ENOG4108XI2 Domain of unknown function (DUF1963) BF28_303 ENOG4108MES Periplasmic binding protein BF28_3031 ENOG4108Z4K mutator MutT protein BF28_3032 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF28_3033 ENOG4105E09 nadh pyrophosphatase BF28_3034 ENOG4105FCD Major Facilitator BF28_304 ENOG4105DCI Phosphohydrolase BF28_3043 ENOG4107Y9U Membrane BF28_3048 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF28_305 ENOG41069HH 4-oxalocrotonate tautomerase BF28_3052 ENOG4107Y80 Major Facilitator superfamily BF28_3054 ENOG4105E09 nadh pyrophosphatase BF28_3057 ENOG4105NA0 Transcriptional regulator BF28_306 ENOG4108Z4T Peptidase M50 BF28_3062 ENOG4108V4B ThiJ pfpI BF28_307 ENOG4108XFG YwhD family BF28_3072 ENOG4105CJN penicillin-binding protein BF28_3073 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF28_3074 ENOG4105CB2 alcohol dehydrogenase BF28_3075 ENOG4108MTT Glutamate-rich protein grpB BF28_3077 ENOG4108HGU Histidine kinase BF28_308 ENOG4105BZ4 penicillin-binding protein BF28_3084 ENOG4107RF6 penicillin-binding protein BF28_3085 ENOG4105BZU Histidine kinase BF28_3086 ENOG410667J hydrolase BF28_309 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF28_310 ENOG4107SWG transcriptional regulator MERR family BF28_3102 ENOG4108TFU terminase (Small subunit) BF28_311 ENOG4105DXB Major Facilitator superfamily BF28_3111 ENOG4105ETU transcriptional activator (TenA BF28_3114 ENOG4105D6E homoserine dehydrogenase BF28_3128 ENOG4105DK7 lysyl-tRNA synthetase BF28_313 ENOG4105CYW agmatinase BF28_3130 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BF28_3132 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF28_3133 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF28_3137 ENOG410900G Protein of unknown function (DUF421) BF28_3138 ENOG4105CPQ Dehydrogenase BF28_3150 ENOG41089UC methyltransferase, type 11 BF28_3151 ENOG4107Y80 Major Facilitator superfamily BF28_3153 ENOG4105FQP Beta-lactamase BF28_3164 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BF28_3165 ENOG4105T9C HD domain BF28_317 ENOG410684U Domain of unknown function (DUF1934) BF28_3171 ENOG4105DBI uridine monophosphokinase BF28_3172 ENOG4105WCN acetyltransferase BF28_3176 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF28_3177 ENOG4107QX3 carboxylase BF28_3178 ENOG4105E39 Enoyl-CoA hydratase BF28_3179 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BF28_3180 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BF28_3181 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF28_3182 ENOG4105C1G acyl-Coa dehydrogenase BF28_3185 ENOG4107Z3H Transcriptional regulator, TetR family BF28_3187 ENOG4105CJ1 ABC, transporter BF28_319 ENOG4105EMN RNA polymerase sigma factor BF28_3190 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BF28_3194 ENOG4105BZU Histidine kinase BF28_3195 ENOG4105C5H ABC transporter BF28_3196 ENOG41067SE Tetr family transcriptional regulator BF28_3197 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BF28_3200 ENOG4108VXD carboxy-peptidase BF28_3202 ENOG4105D7V transposase BF28_3203 ENOG4105VZ8 Transcriptional regulator BF28_3206 ENOG4105CGH 5'-nucleotidase BF28_3210 ENOG4105DH8 myo-inositol catabolism BF28_3216 ENOG4105CK5 oxidoreductase BF28_3217 ENOG4105IE8 Alpha-ketoglutarate permease BF28_3218 ENOG4105ETE Transcriptional regulator (LacI family BF28_3219 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF28_3221 ENOG4107RF6 penicillin-binding protein BF28_3222 ENOG4107RF6 penicillin-binding protein BF28_3228 ENOG4105CIN aminoacyl-histidine dipeptidase BF28_323 ENOG4105IIU Aminopeptidase BF28_3235 ENOG41090HR transcriptional regulator BF28_3236 ENOG4107RA9 decarboxylase BF28_3239 ENOG41088CC tellurite resistance protein tehB BF28_3243 ENOG4108RZE Tetr family transcriptional regulator BF28_3245 ENOG4105C1J atp-dependent rna helicase BF28_3247 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF28_325 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BF28_3251 ENOG4107STF Involved in phosphonate degradation (By similarity) BF28_3253 ENOG4105RD7 BadF BadG BcrA BcrD BF28_3258 ENOG4105F32 YngK protein BF28_326 ENOG4108M15 ABC transporter BF28_3263 ENOG4108KPJ rna polymerase sigma factor BF28_3266 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF28_327 ENOG4105KCT ABC transporter BF28_3273 ENOG4108JCI Transcriptional regulator BF28_3277 ENOG4105BZ1 (ABC) transporter BF28_3278 ENOG4105BZ1 (ABC) transporter BF28_328 ENOG4105BZU Histidine kinase BF28_3281 ENOG4108RPX mosc domain containing protein BF28_3282 ENOG4105DND Transcriptional regulator BF28_3285 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF28_3286 ENOG4107V2S Transcriptional regulator BF28_3293 ENOG4105VEQ Cold shock protein BF28_3295 ENOG41068WN BF28_3299 ENOG4105C1Q protoporphyrinogen oxidase BF28_3305 ENOG4105WCN acetyltransferase BF28_3310 ENOG4105EYF MMPL domain protein BF28_3312 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF28_3315 ENOG41081I9 integral membrane protein BF28_3319 ENOG4108D32 Methyltransferase BF28_332 ENOG4105BZU Histidine kinase BF28_3325 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF28_3327 ENOG4105C19 ABC transporter BF28_3328 ENOG4105C22 threonyL-tRNA synthetase BF28_3329 ENOG4105FE9 pseudouridine synthase BF28_3333 ENOG4105BZG amino acid carrier protein BF28_3337 ENOG4105K70 DNA-binding protein BF28_3340 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_3342 ENOG4105CEY Amp-dependent synthetase and ligase BF28_3343 ENOG4105WQI isochorismatase BF28_3344 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BF28_3345 ENOG4105E4F Isochorismate synthase BF28_3346 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BF28_3347 ENOG4105FCD Major Facilitator BF28_335 ENOG4105DF6 Fe-S oxidoreductase BF28_3351 ENOG4105EYH Exonuclease BF28_3352 ENOG4107RFY SbcCD D subunit BF28_3355 ENOG4105E39 Enoyl-CoA hydratase BF28_3356 ENOG4105N14 lysine exporter protein LysE YggA BF28_3358 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF28_3359 ENOG4105C1G acyl-Coa dehydrogenase BF28_3360 ENOG4105CR4 methylisocitrate lyase BF28_3361 ENOG4105DXD 2-methylcitrate dehydratase BF28_3363 ENOG4105W8X HesB YadR YfhF-family protein BF28_3364 ENOG4105CZM Major Facilitator BF28_3365 ENOG4105BZ4 penicillin-binding protein BF28_337 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BF28_3373 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF28_338 ENOG4105C1G acyl-Coa dehydrogenase BF28_3388 ENOG4105SZ6 Thioredoxin BF28_3389 ENOG410841Q phosphoesterase PA-phosphatase related protein BF28_339 ENOG4105C1G acyl-Coa dehydrogenase BF28_3391 ENOG4108N23 SpoOM-related protein BF28_3399 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BF28_34 ENOG41067V7 50S ribosomal protein L36 BF28_3400 ENOG4108JUB Transcriptional regulator BF28_3401 ENOG4108TSC N-acetyltransferase BF28_3402 ENOG4107S4Y M20 DapE family protein YgeY BF28_3405 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF28_3411 ENOG4105C37 (CBS) domain BF28_3418 ENOG4105E90 ABC transporter BF28_3419 ENOG4108IJ8 ABC transporter BF28_3425 ENOG4108YV3 Protein of unknown function (DUF2711) BF28_3431 ENOG4106KNT transcriptional regulator BF28_3432 ENOG4105WH1 Two component transcriptional regulator luxr family BF28_3433 ENOG4105BZU Histidine kinase BF28_3434 ENOG4105D8X mechanosensitive ion channel BF28_3441 ENOG4105F0I Aminotransferase BF28_3442 ENOG4108MES Periplasmic binding protein BF28_3446 ENOG4105CAQ asparagine synthetase BF28_3447 ENOG4107Y70 Heat shock protein BF28_3448 ENOG4108KF3 Electron transport protein SCO1 SenC BF28_3449 ENOG4105E8R UPF0173 metal-dependent hydrolase BF28_3450 ENOG4108RCR degv family BF28_3452 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BF28_3454 ENOG4108UT2 hemolysin iii BF28_3455 ENOG4105E9Q Acyl-transferase BF28_3457 ENOG4107RVG penicillin-binding protein BF28_346 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BF28_3461 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BF28_3465 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BF28_347 ENOG4105CBT Fructose-1,6-bisphosphatase BF28_3470 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BF28_3471 ENOG4105KD7 acetyltransferase BF28_3474 ENOG4105C0A alcohol dehydrogenase BF28_3475 ENOG4105CY2 Citrate transporter BF28_3476 ENOG4107XGZ Hydrolase BF28_348 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BF28_3480 ENOG4105C8J )-transporter BF28_3493 ENOG4105EC2 ftsk spoIIIe BF28_3497 ENOG4105C5S asparaginyl-tRNA synthetase BF28_3498 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF28_3505 ENOG4107YX5 Pfam:DUF548 BF28_351 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BF28_3511 ENOG4108UUM single-stranded DNA-binding protein BF28_3514 ENOG4105C5H ABC transporter BF28_352 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BF28_3522 ENOG4105MCT stage V sporulation protein S BF28_3529 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BF28_353 ENOG4108ZXQ stage ii sporulation protein r BF28_3530 ENOG4108IFG nitrite reductase, (NAD(P)H) BF28_3531 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BF28_3532 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF28_3533 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF28_3534 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF28_3539 ENOG4108ZAF Molybdopterin BF28_3540 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF28_3541 ENOG4105D06 uba thif-type nad fad binding protein BF28_3542 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF28_3543 ENOG4107V6Q Cyclic nucleotide-binding domain BF28_3545 ENOG4105R3A Nitrate reductase BF28_3546 ENOG4108IUE nitrate reductase beta subunit BF28_355 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF28_3550 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF28_3553 ENOG4108V06 Glutathione peroxidase BF28_3555 ENOG4105CNW domain protein BF28_3558 ENOG4105EMN RNA polymerase sigma factor BF28_3559 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BF28_3561 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BF28_3562 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BF28_3566 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BF28_3571 ENOG4105KBJ sporulation protein ytfj BF28_3584 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF28_3590 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF28_3591 ENOG4108JYZ YitT family BF28_3592 ENOG41087PP glycosyltransferase MGT family BF28_3595 ENOG4107UWY Methyltransferase BF28_3596 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF28_3598 ENOG4108X4Q Hydrolase BF28_36 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF28_360 ENOG4107XC4 flavin reductase domain protein, FMN-binding BF28_3603 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF28_3605 ENOG4108VXD carboxy-peptidase BF28_3607 ENOG4108ZRV stage ii sporulation protein p BF28_361 ENOG4108VGI doxx family BF28_3610 ENOG4108Z7R Chaperone CsaA BF28_3614 ENOG4105C37 (CBS) domain BF28_3615 ENOG4105SXS Protein of unknown function (DUF456) BF28_3619 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF28_3620 ENOG4108S4H thioesterase Superfamily protein BF28_3622 ENOG4108PJD permease BF28_3625 ENOG4107T5V SNARE associated Golgi BF28_3629 ENOG4105CVJ phosphoglycerate mutase BF28_3634 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF28_3636 ENOG4105K4T epimerase BF28_3638 ENOG4105DSE periplasmic solute binding protein BF28_364 ENOG4108YZG isomerase BF28_3649 ENOG4105CKI cobalamin synthesis protein BF28_3650 ENOG4107QM2 Aldo Keto reductase BF28_3654 ENOG4105DEN Luciferase family BF28_3657 ENOG4108WPJ Ferritin-like domain BF28_3658 ENOG4108K88 Membrane BF28_3661 ENOG4105C8Q Methyl-accepting chemotaxis BF28_3666 ENOG4107XZQ multidrug resistance protein BF28_3667 ENOG4107SET aldo keto reductase BF28_3668 ENOG4105YVS arsR family transcriptional regulator BF28_3670 ENOG4105KRN Transcriptional regulator, abrb family BF28_3680 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF28_3681 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BF28_3683 ENOG4105YWU small acid-soluble spore protein BF28_3684 ENOG4108WBH protein TIM barrel BF28_3687 ENOG4105CEY Amp-dependent synthetase and ligase BF28_3688 ENOG4105DUU IucA IucC family protein BF28_369 ENOG41062M3 atp synthase BF28_3690 ENOG4105VRR gCN5-related N-acetyltransferase BF28_3691 ENOG4105KT7 mgtC SapB transporter BF28_3693 ENOG4107VMI polysaccharide deacetylase BF28_3694 ENOG4105BZU Histidine kinase BF28_3695 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_3697 ENOG4108KGH TRANSCRIPTIONal BF28_370 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BF28_3702 ENOG4105D6E homoserine dehydrogenase BF28_3706 ENOG4108ZJ4 polysaccharide deacetylase BF28_3707 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BF28_3710 ENOG4105BZU Histidine kinase BF28_3712 ENOG4105EFI regulatoR BF28_3713 ENOG4105BZ1 (ABC) transporter BF28_3718 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF28_3721 ENOG4108JJ8 (ABC) transporter BF28_3722 ENOG4108JJ9 ABC, transporter BF28_3723 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF28_3724 ENOG4105C4M (Ubiquinol oxidase) subunit I BF28_3730 ENOG4105SKE transcriptional Regulator LysR family BF28_3732 ENOG4105C32 Amino acid ABC transporter (Permease) BF28_3733 ENOG4108IV0 ABC, transporter BF28_3734 ENOG4105C0Z ABC transporter BF28_3736 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF28_3737 ENOG4108Z7G MaoC domain protein dehydratase BF28_3741 ENOG4105CKI cobalamin synthesis protein BF28_3743 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF28_3744 ENOG4106F5Q Membrane BF28_3745 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF28_3747 ENOG4108TVJ Nitroreductase BF28_3748 ENOG4107ZXU DSBA oxidoreductase BF28_3749 ENOG4108Z40 Transcriptional regulator BF28_3750 ENOG4105GZI Transcriptional regulator BF28_3751 ENOG4107RT3 EamA-like transporter family BF28_3753 ENOG4105KTB nuclear export factor GLE1 BF28_3754 ENOG4108T5E Copper resistance protein BF28_3767 ENOG4105BZ1 (ABC) transporter BF28_3773 ENOG4107RAQ aminopeptidase BF28_3779 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BF28_3780 ENOG4105D9N nucleoside BF28_3782 ENOG4107RHR regulatoR BF28_3787 ENOG4105C0X amino acid BF28_3789 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BF28_3792 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BF28_3797 ENOG41068WN BF28_38 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF28_380 ENOG4105BZU Histidine kinase BF28_3803 ENOG4105F6J Alpha beta hydrolase fold BF28_3807 ENOG4105CYC Transferase BF28_3808 ENOG4105DY9 regulatoR BF28_381 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BF28_3810 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BF28_3811 ENOG4105C6X Major Facilitator BF28_3816 ENOG4105C7B Threonine dehydratase BF28_3820 ENOG4105C7K acetolactate synthase BF28_3821 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF28_3822 ENOG4105CHR reductase BF28_3823 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BF28_3826 ENOG4105H67 Protein of unknown function (DUF421) BF28_3827 ENOG4105X5K response regulator receiver protein BF28_3829 ENOG4105C8J )-transporter BF28_383 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BF28_3833 ENOG4105C6T cysteine synthase BF28_3834 ENOG4105EU0 Major facilitator Superfamily BF28_3836 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF28_3839 ENOG4105DXI Major Facilitator superfamily BF28_3841 ENOG4105U3E Transcriptional regulator BF28_3842 ENOG4105CSR polyphosphate kinase 2 BF28_3844 ENOG4105DE4 1-phosphofructokinase BF28_3846 ENOG4105CE4 GlcNAc 6-P deacetylase BF28_3847 ENOG4105E70 isomerase BF28_3848 ENOG4108X79 transcriptional regulator BF28_3850 ENOG4105DRS transport system, permease BF28_3851 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BF28_3861 ENOG4105FVX BF28_3866 ENOG41067QW Transcriptional regulator BF28_3872 ENOG4105C6K Malic enzyme BF28_3873 ENOG4108IJ0 Aspartate ammonia-lyase BF28_3875 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BF28_3879 ENOG4105CJ1 ABC, transporter BF28_3886 ENOG4106BRA Membrane BF28_389 ENOG4105D65 subunit l BF28_3891 ENOG4107QIV Cytochrome c biogenesis protein BF28_3895 ENOG4105EC3 peptidase S51, dipeptidase E BF28_3896 ENOG4107QJQ Mate efflux family protein BF28_3899 ENOG4105C9Q fumarate hydratase class II BF28_390 ENOG4105C8S subunit m BF28_3900 ENOG4105DFD Na H antiporter BF28_3902 ENOG4105CKI cobalamin synthesis protein BF28_3903 ENOG4108UZ3 Transporter BF28_3904 ENOG4105DRR Transcriptional regulator, GntR family BF28_3906 ENOG4105PGM cation diffusion facilitator family transporter BF28_391 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BF28_3910 ENOG4105CAQ asparagine synthetase BF28_3912 ENOG4105K56 Transcriptional regulator BF28_3914 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BF28_3916 ENOG4105CVJ phosphoglycerate mutase BF28_392 ENOG4106778 Protein of unknown function (DUF1146) BF28_3923 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BF28_3924 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BF28_3925 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF28_3926 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF28_3927 ENOG4105DUM transcriptional regulator, lysR family BF28_3932 ENOG4105KAC Antibiotic biosynthesis monooxygenase BF28_3936 ENOG4108RZE Tetr family transcriptional regulator BF28_3941 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF28_3942 ENOG4105KTQ flagellar basal-body rod protein BF28_3943 ENOG4105FZW flagellar biosynthesis regulator FlhF BF28_3944 ENOG4105D7B Flagellar biosynthesis protein flha BF28_3945 ENOG4105D00 flagellar biosynthetic protein flhB BF28_3947 ENOG4105VS8 Flagellar biosynthetic protein fliq BF28_3948 ENOG4105CN7 Flagellar biosynthetic protein FliP BF28_3950 ENOG4105DD5 Flagellar motor switch protein BF28_3951 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF28_3953 ENOG4105E4C Lytic transglycosylase catalytic BF28_3954 ENOG4105I03 Flagellin BF28_3954 ENOG4105I03 Flagellin BF28_3955 ENOG4105I03 Flagellin BF28_3957 ENOG4107R88 Chemotaxis protein (CheV) BF28_396 ENOG4105DY9 regulatoR BF28_3960 ENOG4105BZE flagellar hook protein, FlgE BF28_3966 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF28_3967 ENOG4107U2N Flagellar M-ring protein BF28_3968 ENOG41075Z6 flagellar hook-basal body complex protein fliE BF28_3969 ENOG4108ZC9 flagellar basal-body rod protein flgc BF28_3970 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BF28_3973 ENOG4105DTS flagellar hook-associated BF28_3974 ENOG4105DTJ flagellar hook-associated protein BF28_3975 ENOG4105E1Q flagellar hook-associated protein BF28_3979 ENOG4105BZU Histidine kinase BF28_3982 ENOG4105DD5 Flagellar motor switch protein BF28_3983 ENOG4105CBS Chea signal transduction histidine kinase BF28_3984 ENOG4107YTP response regulator receiver protein BF28_3985 ENOG4105ER2 Ompa motb domain protein BF28_3986 ENOG4107R0U MotA TolQ exbB proton channel BF28_3988 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BF28_399 ENOG4105FRN stage II sporulation protein BF28_4001 ENOG41080C8 DUF218 domain BF28_4002 ENOG4105H67 Protein of unknown function (DUF421) BF28_4004 ENOG4108Z5V transcriptional regulator, merr family BF28_4005 ENOG4105CN5 Metallo-Beta-Lactamase BF28_4006 ENOG4107RWR Sodium hydrogen exchanger BF28_4008 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF28_4021 ENOG41081VK Ribonuclease BF28_4025 ENOG4108SZE gCN5-related N-acetyltransferase BF28_403 ENOG4108UW5 maltose o-acetyltransferase BF28_4031 ENOG4106032 Glutathionylspermidine synthase BF28_4034 ENOG4105KHC sulfurtransferase BF28_4036 ENOG4108W0I acetyltransferase BF28_4038 ENOG410890F Dynamin family BF28_4040 ENOG4105DHF Membrane BF28_4041 ENOG4105C2W permease BF28_4043 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF28_4046 ENOG4105CTD carboxy-peptidase BF28_4047 ENOG4105DVT helicase BF28_4049 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BF28_405 ENOG4107BJW polysaccharide deacetylase BF28_406 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BF28_4060 ENOG4105BZ4 penicillin-binding protein BF28_4062 ENOG4105CSM endonuclease III BF28_4066 ENOG4105YAC BF28_4067 ENOG4105DVT helicase BF28_4074 ENOG4105CPK Glycosyl transferase (Group 1 BF28_4075 ENOG4105FJR Lmbe family BF28_4078 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BF28_4079 ENOG4108JYZ YitT family BF28_4085 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BF28_4086 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BF28_4087 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BF28_4090 ENOG41068YB TPR repeat-containing protein BF28_4095 ENOG4105EAH synthase BF28_4097 ENOG4105XXQ heptaprenyl diphosphate synthase component I BF28_4100 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BF28_4106 ENOG41065D1 BF28_4107 ENOG4105S2F BF28_4114 ENOG4107RB3 L-asparaginase BF28_4115 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BF28_4120 ENOG4108S6Z Negative regulator of genetic competence BF28_4121 ENOG4107X2D transcriptional regulator, merr family BF28_4122 ENOG4107RGJ metallophosphoesterase BF28_4124 ENOG4105I7S Abortive infection protein BF28_4125 ENOG4105C9U ATP-dependent DNA helicase RecQ BF28_4128 ENOG4108SAX Membrane BF28_4130 ENOG41063SB peptidase BF28_4131 ENOG4108WBT adenosyltransferase BF28_4132 ENOG4105BZU Histidine kinase BF28_4133 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_4134 ENOG4105CRE cytochrome C BF28_4135 ENOG4107TWT Cytochrome c biogenesis protein BF28_4137 ENOG4105FE9 pseudouridine synthase BF28_4139 ENOG4108JIC nucleoside recognition domain protein BF28_4140 ENOG4105DZ1 carboxypeptidase BF28_4141 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF28_4148 ENOG4105BZU Histidine kinase BF28_4151 ENOG4105I3N Conserved Protein BF28_4152 ENOG4105BZU Histidine kinase BF28_4155 ENOG4105BZ4 penicillin-binding protein BF28_4156 ENOG4107GRR phosphate transport regulator BF28_4157 ENOG4105CJ3 phosphate transporter BF28_4166 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BF28_4170 ENOG4105WH1 Two component transcriptional regulator luxr family BF28_4171 ENOG4105ENE Histidine kinase BF28_4175 ENOG4105DFD Na H antiporter BF28_4179 ENOG4105C8J )-transporter BF28_418 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF28_4180 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF28_4181 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF28_4182 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF28_4184 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BF28_4185 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BF28_4189 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BF28_4191 ENOG4105E0M Sulfatase BF28_4192 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF28_4195 ENOG4107RVV histidinol phosphate phosphatase, hisj family BF28_4210 ENOG4108ZP8 Acetolactate synthase small subunit BF28_4211 ENOG4105C7K acetolactate synthase BF28_4212 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF28_4216 ENOG4105KBJ sporulation protein ytfj BF28_4217 ENOG41063Y9 BF28_4218 ENOG4105CZN Potassium uptake protein BF28_422 ENOG4105CMR udp-glucose 4-epimerase BF28_4224 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BF28_423 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_4232 ENOG4105NQC Flavodoxin BF28_4237 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF28_4239 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF28_424 ENOG4105BZU Histidine kinase BF28_4240 ENOG4105EA8 2-Nitropropane dioxygenase BF28_4241 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF28_4249 ENOG4105CJ1 ABC, transporter BF28_4251 ENOG4105CZV ABC transporter BF28_4252 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF28_4253 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF28_4254 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF28_4255 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF28_4256 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BF28_4264 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BF28_4265 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BF28_4267 ENOG4105BZU Histidine kinase BF28_4269 ENOG4106DF1 BF28_427 ENOG4105CXY transporter BF28_4271 ENOG41090MY MarR family Transcriptional regulator BF28_4272 ENOG4105BZU Histidine kinase BF28_4274 ENOG4105PXI polysaccharide deacetylase BF28_4276 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BF28_4279 ENOG4105E98 transcriptional regulator DeoR family BF28_4283 ENOG4107RCV ABC transporter, permease BF28_4284 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF28_4285 ENOG4105C4Y ABC transporter BF28_4291 ENOG4105CHR reductase BF28_4295 ENOG4108Z7G MaoC domain protein dehydratase BF28_4296 ENOG410681C small acid-soluble spore protein BF28_4297 ENOG4105CZN Potassium uptake protein BF28_4298 ENOG4107TS3 membrane protein, TerC BF28_4299 ENOG4108QTI )-transporter BF28_43 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BF28_4301 ENOG4106A3R peptidase BF28_4305 ENOG4105JXH GntR family transcriptional regulator BF28_4306 ENOG4105BZU Histidine kinase BF28_4307 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_431 ENOG4105C19 ABC transporter BF28_4310 ENOG4105CQB FAD linked oxidase domain protein BF28_4311 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BF28_4312 ENOG4105K4I Scp-like extracellular BF28_4314 ENOG4108YBP pseudouridine synthase BF28_4316 ENOG4105EYF MMPL domain protein BF28_4318 ENOG4107RUE extracellular solute-binding protein family 1 BF28_4319 ENOG4105D38 putrescine abc transporter BF28_432 ENOG4107RBB ABC transporter, permease BF28_4320 ENOG4105F38 ABC transporter, permease BF28_4322 ENOG4105C26 Dehydrogenase BF28_4328 ENOG4105VFR signal peptidase BF28_4329 ENOG4105DZ1 carboxypeptidase BF28_4331 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BF28_4349 ENOG4105VZ8 Transcriptional regulator BF28_435 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_4351 ENOG4105C7S Dehydrogenase BF28_4355 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BF28_4370 ENOG4105DDQ anthranilate synthase BF28_4371 ENOG4105CRQ synthase (Component I) BF28_4372 ENOG4105CK7 Sodium proline symporter BF28_4386 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BF28_4388 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BF28_4389 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BF28_4393 ENOG4107TVC Glycosyl transferase, family 2 BF28_4397 ENOG4105K64 Glycosyl transferase, family 2 BF28_4401 ENOG4105EMS pseudouridine synthase BF28_4402 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BF28_4405 ENOG4105MIX Adenylate cyclase BF28_4406 ENOG4108Z18 K06886 hemoglobin BF28_4409 ENOG4105DPN Oligoendopeptidase f BF28_441 ENOG4105C0D helicase BF28_4411 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF28_4413 ENOG4108ZCF integral membrane protein BF28_4417 ENOG4105UQX Mate efflux family protein BF28_4418 ENOG4108JQ7 (ABC) transporter BF28_442 ENOG4105KBK Zinc finger, swim domain protein BF28_4420 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF28_4421 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF28_4424 ENOG4105C31 Tryptophanyl-tRNA synthetase BF28_4427 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF28_4428 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF28_4433 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF28_4435 ENOG4108KP7 hydrolase BF28_4437 ENOG41073B9 BF28_4438 ENOG4107AYK membrAne BF28_4440 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF28_4441 ENOG4105QNR S1 RNA binding domain protein BF28_4445 ENOG4105BZU Histidine kinase BF28_4446 ENOG4105CH6 catalase BF28_4448 ENOG4105CAQ asparagine synthetase BF28_4453 ENOG4105ERH Fumarylacetoacetate hydrolase BF28_4466 ENOG4105XVF Competence transcription factor BF28_4469 ENOG4105VEQ Cold shock protein BF28_447 ENOG41069ER domain protein BF28_4472 ENOG4107QP3 malate synthase g BF28_4473 ENOG4105ZU5 s-layer protein BF28_4477 ENOG4105C8Q Methyl-accepting chemotaxis BF28_4478 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BF28_448 ENOG4105C94 Transporter BF28_4483 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_4486 ENOG41086D8 Transcriptional regulator BF28_4487 ENOG4108AEY RNA polymerase sigma factor BF28_4489 ENOG4107TVP HD domain protein BF28_4490 ENOG4107RN3 metallophosphoesterase BF28_4491 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BF28_4494 ENOG4105CEY Amp-dependent synthetase and ligase BF28_4496 ENOG4105DF9 Lipoate-protein, ligase BF28_4497 ENOG4108RQ5 Beta-lactamase domain-containing protein BF28_4498 ENOG4106AXD BF28_450 ENOG4107R8N Glycosyl transferase, family 2 BF28_4500 ENOG4105D29 Helix-turn-helix type 11 domain protein BF28_4502 ENOG4108MK9 spermidine N(1)-acetyltransferase BF28_4505 ENOG4105ECB domain protein BF28_4508 ENOG4105NA0 Transcriptional regulator BF28_4513 ENOG4105C1Q protoporphyrinogen oxidase BF28_4516 ENOG4105BZ4 penicillin-binding protein BF28_4517 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BF28_4518 ENOG4105CKV Membrane BF28_4519 ENOG410905X membrane-flanked domain protein BF28_4527 ENOG4105CKV Membrane BF28_4528 ENOG410905X membrane-flanked domain protein BF28_4547 ENOG4105K59 histidine triad (HIT) protein BF28_455 ENOG4105E0M Sulfatase BF28_4552 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF28_4553 ENOG4105EEM helicase BF28_4555 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_4556 ENOG4105C57 major facilitator superfamily BF28_4561 ENOG4105EMN RNA polymerase sigma factor BF28_4564 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BF28_4567 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF28_457 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BF28_4572 ENOG4108MUZ hydrolase BF28_4583 ENOG4106D4I domain protein BF28_4584 ENOG4107VRP DNA repair exonuclease BF28_459 ENOG4105DAA L-lactate BF28_4595 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_4597 ENOG4105K8R UPF0145 protein BF28_4602 ENOG4105BZU Histidine kinase BF28_4603 ENOG4105BZU Histidine kinase BF28_4604 ENOG4108MJI response regulator BF28_4606 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_4608 ENOG4105WN5 stage II sporulation protein BF28_4622 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BF28_4629 ENOG410847I Transcriptional regulator, BadM Rrf2 family BF28_463 ENOG4105DAA L-lactate BF28_4631 ENOG4105CMT Dihydroxyacetone kinase BF28_4633 ENOG4105CMT Dihydroxyacetone kinase BF28_4639 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF28_4641 ENOG4105CS2 ec 3.2.1.21 BF28_4642 ENOG4105C5Y PTS System BF28_4643 ENOG4105CID antiterminator BF28_4645 ENOG4108IG5 Transcriptional regulator BF28_4646 ENOG4107P5I polyketide synthase BF28_4662 ENOG4105CDU Replicative dna helicase BF28_4672 ENOG4105C3J Cysteine desulfurase BF28_4674 ENOG4105EYH Exonuclease BF28_4676 ENOG4105D7A ATP-binding protein BF28_4686 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BF28_4690 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BF28_4692 ENOG4108JQ7 (ABC) transporter BF28_4694 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF28_470 ENOG4107RSM transcriptional regulator BF28_4701 ENOG4105CTU Proline racemase BF28_4705 ENOG4105DER m42 family BF28_4709 ENOG4105CGU Enoyl-CoA hydratase BF28_471 ENOG4105ECB domain protein BF28_4713 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF28_4714 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF28_4716 ENOG4106AKK s-layer domain-containing protein BF28_472 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BF28_4724 ENOG4105CHH sulfate transporter BF28_4726 ENOG4105CEY Amp-dependent synthetase and ligase BF28_4727 ENOG4105D4P Coproporphyrinogen iii oxidase BF28_4728 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF28_4732 ENOG4107FQX Alpha-acetolactate decarboxylase BF28_4741 ENOG4105WH1 Two component transcriptional regulator luxr family BF28_4742 ENOG4105BZU Histidine kinase BF28_4747 ENOG410839P BF28_475 ENOG4105VZJ PTS System BF28_4750 ENOG4105CDA abc transporter atp-binding protein BF28_4751 ENOG4105DRP amino acid AbC transporter BF28_4753 ENOG4105BZ1 (ABC) transporter BF28_4754 ENOG4105BZ1 (ABC) transporter BF28_4755 ENOG4105C26 Dehydrogenase BF28_4756 ENOG4105D5Q Arginine ornithine antiporter BF28_4758 ENOG4105CH6 catalase BF28_4759 ENOG4107RKG DJ-1/PfpI family BF28_4761 ENOG4105E5W Transporter BF28_4762 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF28_4763 ENOG4105NF4 modulator of drug activity BF28_4768 ENOG4106A3M Cytochrome p-450 BF28_4769 ENOG4105YA8 Transcriptional regulator BF28_477 ENOG4105VCP PTS System BF28_4771 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_4772 ENOG41061H0 Monooxygenase BF28_4773 ENOG41082F9 transcriptional regulator BF28_4777 ENOG4105KPY Small multidrug resistance protein BF28_4778 ENOG4105KPY Small multidrug resistance protein BF28_4780 ENOG4108YXU transcriptional regulator AsnC family BF28_4788 ENOG4105C5Y PTS System BF28_479 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BF28_4790 ENOG4106KNT transcriptional regulator BF28_4792 ENOG4107RWR Sodium hydrogen exchanger BF28_4793 ENOG4105CUB amino acid BF28_4800 ENOG4107T5V SNARE associated Golgi BF28_4807 ENOG4105WEF catalase BF28_481 ENOG4105CK1 PTS System BF28_4814 ENOG4105C19 ABC transporter BF28_4815 ENOG4107RBB ABC transporter, permease BF28_4816 ENOG41069ER domain protein BF28_482 ENOG4105VCP PTS System BF28_4820 ENOG4105VZJ PTS System BF28_4821 ENOG4105VCP PTS System BF28_4822 ENOG4105EMD TRANSCRIPTIONal BF28_4827 ENOG4108KGH TRANSCRIPTIONal BF28_4829 ENOG41087NI Sulfite exporter TauE/SafE BF28_483 ENOG4105F8D glycoside hydrolase family 4 BF28_4830 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BF28_4832 ENOG41085GJ domain protein BF28_4833 ENOG4105VFE sira family BF28_4834 ENOG4107TPS domain protein BF28_4835 ENOG4105VFE sira family BF28_4836 ENOG4105XTG Pfam:DUF156 BF28_4837 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BF28_4839 ENOG4105ED1 spovr family BF28_484 ENOG410901P UPF0249 protein BF28_4840 ENOG4107Y03 Nitroreductase BF28_4844 ENOG4108B31 Spore germination protein BF28_4851 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BF28_4853 ENOG4105C7N Xanthine uracil vitamin C permease BF28_4856 ENOG4108INS Transcriptional regulator BF28_4865 ENOG4105DWF phosphomethylpyrimidine kinase BF28_4866 ENOG4105D06 uba thif-type nad fad binding protein BF28_4869 ENOG41080HI glycine oxidase BF28_487 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BF28_4870 ENOG4108VEU Thiamine monophosphate synthase BF28_4872 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF28_4874 ENOG4105ETU transcriptional activator (TenA BF28_4878 ENOG41080XQ Signal transduction protein with cbs domains BF28_489 ENOG4105ESV Glycosyl transferase, family 4 BF28_490 ENOG4105C6Y Udp-glucose 6-dehydrogenase BF28_4905 ENOG4105E2Z phosphate ABC transporter (Permease BF28_4906 ENOG4105C8U phosphate abc transporter BF28_4907 ENOG4105CVA phosphate BF28_4908 ENOG4105CE1 Ferrous iron transport protein b BF28_4909 ENOG4105CE1 Ferrous iron transport protein b BF28_491 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF28_4910 ENOG4105CE1 Ferrous iron transport protein b BF28_4911 ENOG4108NHD germination protein BF28_4914 ENOG4105E1V na solute symporter BF28_4915 ENOG4106CAD Protein of unknown function (DUF3311) BF28_4918 ENOG4105E2S oxidase) subunit II BF28_4919 ENOG4105BZ9 Cytochrome C oxidase, subunit I BF28_492 ENOG4108KGH TRANSCRIPTIONal BF28_4924 ENOG4105MA6 gCN5-related N-acetyltransferase BF28_4927 ENOG4105C7N Xanthine uracil vitamin C permease BF28_4928 ENOG4105C85 amino acid BF28_493 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BF28_4932 ENOG4105DUX Transporter BF28_4934 ENOG4107D63 BF28_4935 ENOG4105VZ8 Transcriptional regulator BF28_4936 ENOG41069ER domain protein BF28_4937 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF28_495 ENOG4105KVH Transcriptional regulator BF28_4952 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF28_4953 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF28_4954 ENOG4105CNN ABC, transporter BF28_4957 ENOG4108RVA ribokinase BF28_4958 ENOG4105ETE Transcriptional regulator (LacI family BF28_4959 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF28_496 ENOG4105K4H Nlp p60 protein BF28_4960 ENOG41067TZ transcriptional regulator, MarR family BF28_4961 ENOG4105CXY transporter BF28_4963 ENOG4108JQ7 (ABC) transporter BF28_4964 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF28_4966 ENOG4105DEF Extracellular solute-binding protein, family 5 BF28_4968 ENOG41068KF Universal stress protein BF28_4969 ENOG4105CHH sulfate transporter BF28_4972 ENOG4105BZU Histidine kinase BF28_4973 ENOG4105NAE bifunctional deaminase-reductase domain protein BF28_4974 ENOG4105D29 Helix-turn-helix type 11 domain protein BF28_4979 ENOG4108IQI permease BF28_498 ENOG41081UC Inherit from COG: Competence protein BF28_4980 ENOG4105DRP amino acid AbC transporter BF28_4981 ENOG4105EAD ABC transporter BF28_4982 ENOG4105CT1 (ABC) transporter BF28_4983 ENOG4105CDA abc transporter atp-binding protein BF28_4984 ENOG4105BZG amino acid carrier protein BF28_4985 ENOG4105CRN Aminoglycoside phosphotransferase BF28_4987 ENOG4105E1K spore germination protein BF28_499 ENOG4105VEQ Cold shock protein BF28_4990 ENOG4105CG3 alpha amylase, catalytic region BF28_4991 ENOG4105C5Y PTS System BF28_4992 ENOG4107414 GntR family transcriptional regulator BF28_4993 ENOG4105D5Q Arginine ornithine antiporter BF28_4994 ENOG4105BZU Histidine kinase BF28_4997 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF28_4998 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BF28_4999 ENOG4107T89 von Willebrand factor, type A BF28_500 ENOG4105MS2 ribosomal subunit Interface protein BF28_5001 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BF28_5002 ENOG4105EXW epimerase dehydratase BF28_5004 ENOG4105DMQ Methyltransferase BF28_5005 ENOG4105E0A ABC, transporter BF28_5006 ENOG4108IHU transport system permease protein BF28_5007 ENOG4105DQ5 transport system permease protein BF28_5008 ENOG4108MES Periplasmic binding protein BF28_5009 ENOG4105DUX Transporter BF28_5012 ENOG4105DAA L-lactate BF28_5013 ENOG4108IJ0 Aspartate ammonia-lyase BF28_5014 ENOG4105C37 (CBS) domain BF28_5015 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BF28_5016 ENOG4105D9N nucleoside BF28_5017 ENOG4108KGH TRANSCRIPTIONal BF28_5018 ENOG41073R8 VanW family BF28_502 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BF28_5025 ENOG4105DAP Nicotinate phosphoribosyltransferase BF28_5026 ENOG4105C59 p-type ATPase BF28_5028 ENOG4105CUB amino acid BF28_5032 ENOG4108JB9 formate dehydrogenase BF28_5033 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF28_5034 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF28_5036 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_5037 ENOG4105BZU Histidine kinase BF28_5039 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF28_504 ENOG4105CAK Cell division ATP-binding protein ftsE BF28_5040 ENOG4108UZ3 Transporter BF28_5042 ENOG4105C6K Malic enzyme BF28_5044 ENOG4108MRH transcriptional regulatory protein BF28_5049 ENOG4105US7 Histidine kinase BF28_505 ENOG4105CRP Part of the ABC transporter FtsEX involved in BF28_5050 ENOG4108STX response regulator BF28_5051 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BF28_5052 ENOG4105BZ7 extracellular solute-binding protein family 1 BF28_5053 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BF28_5054 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BF28_5055 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF28_5056 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF28_506 ENOG4105CN1 protease BF28_5061 ENOG4105D4T Citrate transporter BF28_5063 ENOG4108V9W transcriptional regulatory protein BF28_5064 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BF28_5066 ENOG4105DZ6 Band 7 protein BF28_5069 ENOG4105C94 Transporter BF28_5070 ENOG4105DRP amino acid AbC transporter BF28_5071 ENOG4105DRP amino acid AbC transporter BF28_5072 ENOG4105CDA abc transporter atp-binding protein BF28_5073 ENOG4105CT1 (ABC) transporter BF28_5078 ENOG4105CYN Serine protein kinase BF28_508 ENOG4105BZ1 (ABC) transporter BF28_5080 ENOG4105BZU Histidine kinase BF28_5081 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BF28_5083 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BF28_5085 ENOG4107ZQN disulfide bond BF28_5086 ENOG4108JQC penicillin-binding protein 1A BF28_511 ENOG4108WS4 fmn reductase BF28_5110 ENOG4105G5W regulator Fur family BF28_5111 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF28_5115 ENOG4108IUW ABC transporter BF28_5117 ENOG4105CBC glutamate synthase BF28_5118 ENOG4107NBY Membrane BF28_5119 ENOG4105BZ1 (ABC) transporter BF28_5123 ENOG4106BXE BF28_5124 ENOG4105CEN a g-specific adenine glycosylase BF28_5125 ENOG41067AE Membrane-bound metal-dependent hydrolase BF28_513 ENOG4105DUM transcriptional regulator, lysR family BF28_5131 ENOG4105ECP epimerase BF28_5132 ENOG4105CI2 imidazolone-5-propionate hydrolase BF28_5136 ENOG4105F1A Pyruvate formate-lyase BF28_5139 ENOG4105C3I Nad-dependent epimerase dehydratase BF28_514 ENOG4105HMI Membrane BF28_5140 ENOG4107QQG Dehydrogenase BF28_5141 ENOG4105CKK Glycosyl transferase, family 2 BF28_5145 ENOG4108A04 Beta-lactamase BF28_5147 ENOG4105CSV Glutaminase BF28_5153 ENOG4108IQI permease BF28_5155 ENOG4108JUB Transcriptional regulator BF28_5158 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF28_5165 ENOG4105UPD Calcium Proton BF28_5166 ENOG410606W general stress protein BF28_5169 ENOG4107ZTW SNARE associated Golgi BF28_5171 ENOG4105C3F Signal peptidase i BF28_5173 ENOG4108IPJ Membrane BF28_5174 ENOG4105C59 p-type ATPase BF28_5175 ENOG4107U9T Pfam:Ribonuclease_BN BF28_5177 ENOG4105KJF protein tyrosine phosphatase BF28_5181 ENOG4108TTB tellurium resistance protein BF28_5182 ENOG4107TS3 membrane protein, TerC BF28_5183 ENOG4106FN3 tellurium resistance protein BF28_5184 ENOG4106FN3 tellurium resistance protein BF28_5185 ENOG4108N0M stress protein BF28_5191 ENOG4105DEU major facilitator superfamily BF28_5195 ENOG41062JF Transcriptional regulator BF28_520 ENOG4107TXC Transcriptional regulator BF28_5200 ENOG4105C5H ABC transporter BF28_5204 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF28_5207 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BF28_5214 ENOG4105CI1 PTS System BF28_5216 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF28_5217 ENOG4105C8Q Methyl-accepting chemotaxis BF28_5219 ENOG4105EAB amino acid AbC transporter BF28_5220 ENOG4105E5Q amino acid AbC transporter BF28_5223 ENOG4105D2S major facilitator superfamily BF28_5224 ENOG410756H nucleotidyltransferase BF28_5229 ENOG4105BZU Histidine kinase BF28_523 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF28_5233 ENOG4106UIA BF28_5234 ENOG4106UIA BF28_5238 ENOG4108V5C ABC transporter BF28_5239 ENOG4105DQ5 transport system permease protein BF28_5240 ENOG4105EHG Permease protein BF28_5241 ENOG4107W7X Aldolase BF28_5243 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BF28_5244 ENOG4105D3R alkyl hydroperoxide reductase BF28_5249 ENOG4105DFD Na H antiporter BF28_525 ENOG41086DT Membrane protein of unknown function BF28_5250 ENOG4105DTQ mandelate racemase muconate lactonizing BF28_5253 ENOG4108W15 Protein of unknown function (DUF1456) BF28_5254 ENOG4105BZU Histidine kinase BF28_5256 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF28_5257 ENOG4105D9N nucleoside BF28_5261 ENOG4105KPY Small multidrug resistance protein BF28_5262 ENOG4105C26 Dehydrogenase BF28_5264 ENOG4108JPW Aminotransferase BF28_5265 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BF28_5266 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BF28_5267 ENOG4105CBD Diacylglycerol kinase BF28_5271 ENOG4107I77 yiaA/B two helix domain BF28_5272 ENOG410834F Transcriptional regulator BF28_5276 ENOG4105D01 (LipO)protein BF28_5277 ENOG4108UMI ABC transporter, permease BF28_5279 ENOG4108W2Y isochorismatase BF28_5285 ENOG4105C4R Atp-dependent dna helicase BF28_529 ENOG4108S4C acetyltransferase BF28_5290 ENOG4105C12 Phosphoribosylglycinamide synthetase BF28_5292 ENOG4108V3E phosphoribosylglycinamide formyltransferase BF28_5297 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BF28_5299 ENOG4105C83 adenylosuccinate lyase BF28_5300 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BF28_5301 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BF28_5302 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BF28_5308 ENOG4105SX7 Transporter BF28_531 ENOG4105C3M thioredoxin reductase BF28_5312 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_5326 ENOG4107ZXU DSBA oxidoreductase BF28_533 ENOG4108Z4K mutator MutT protein BF28_5332 ENOG4105BZU Histidine kinase BF28_5334 ENOG4105C7N Xanthine uracil vitamin C permease BF28_5337 ENOG4107EV6 Inherit from COG: YD repeat protein BF28_5340 ENOG4108TYN CAAX amino terminal protease family protein BF28_5343 ENOG4105C5H ABC transporter BF28_5344 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF28_5345 ENOG410801F ribosomal-protein-alanine acetyltransferase BF28_5346 ENOG41072GX Peptidase M22 Glycoprotease BF28_5347 ENOG4105K8N protein family UPF0079, ATPase BF28_535 ENOG4105CHW UPF0052 protein BF28_5367 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BF28_5369 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF28_537 ENOG4105KRI phosphocarrier protein (HPr BF28_5370 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BF28_5373 ENOG4107ZXI Rhomboid family BF28_5375 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF28_5376 ENOG4105CPF Cell wall formation (By similarity) BF28_5379 ENOG4105ERH Fumarylacetoacetate hydrolase BF28_538 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BF28_5380 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BF28_5386 ENOG410667J hydrolase BF28_5387 ENOG4108JQ7 (ABC) transporter BF28_5388 ENOG4105C3U ABC transporter BF28_5389 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF28_539 ENOG4108QY0 Membrane BF28_5391 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BF28_5395 ENOG4105C5H ABC transporter BF28_5399 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BF28_5401 ENOG4108RE7 deoxyribonuclease BF28_5404 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF28_5408 ENOG4105F6E Acyl-transferase BF28_5415 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BF28_5416 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF28_5417 ENOG4105E0C molybdate abc transporter BF28_5419 ENOG4107XDY Nicotinamide Mononucleotide Transporter BF28_542 ENOG4105CZ3 stage V sporulation protein ad BF28_5421 ENOG4105II7 pyrroline-5-carboxylate reductase BF28_5423 ENOG4108J59 Extracellular solute-binding protein, family 5 BF28_5424 ENOG4108J59 Extracellular solute-binding protein, family 5 BF28_5426 ENOG4105U5Y Transcriptional regulator BF28_543 ENOG41090VF Stage v sporulation protein ac BF28_5431 ENOG4108JQ7 (ABC) transporter BF28_5432 ENOG4105C3U ABC transporter BF28_5433 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF28_5434 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF28_5437 ENOG4105C2C drug resistance transporter, Bcr CflA BF28_5440 ENOG4105IQ5 FAD linked oxidase domain protein BF28_5442 ENOG4105EE1 crotonyl-CoA reductase BF28_5443 ENOG4105D01 (LipO)protein BF28_5445 ENOG4108UMI ABC transporter, permease BF28_5446 ENOG4108PSK reductase BF28_5452 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BF28_5453 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BF28_5455 ENOG4105CMG Carbohydrate kinase BF28_5457 ENOG4108VQT Alpha beta hydrolase fold protein BF28_5461 ENOG4105D7V transposase BF28_5466 ENOG4105C9U ATP-dependent DNA helicase RecQ BF28_5471 ENOG4105CHM Aminotransferase BF28_5474 ENOG4105C6E dna polymerase iii BF28_5480 ENOG4105DQ6 Transposase BF28_5481 ENOG4105DH8 myo-inositol catabolism BF28_5482 ENOG4105D2N Aldolase BF28_5483 ENOG4105ETE Transcriptional regulator (LacI family BF28_5488 ENOG4105CK5 oxidoreductase BF28_5489 ENOG4105IE8 Alpha-ketoglutarate permease BF28_5490 ENOG4105ETE Transcriptional regulator (LacI family BF28_5491 ENOG4105ETE Transcriptional regulator (LacI family BF28_5492 ENOG4107QNK )-transporter BF28_5493 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BF28_5510 ENOG4108M1A Chitin-binding protein BF28_5515 ENOG4105D7V transposase BF28_5519 ENOG4108T9Y Inner membrane protein ydcZ BF28_552 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_5520 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) BF28_5521 ENOG4105CS7 Catalyzes the conversion of dihydroorotate to orotate BF28_5524 ENOG4105BZ8 glutamate synthase BF28_5525 ENOG4107XGZ Hydrolase BF28_5526 ENOG4108Z7R Chaperone CsaA BF28_5542 ENOG4105RHY Pfam:UPF0157 BF28_5555 ENOG4105K4H Nlp p60 protein BF28_5576 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF28_558 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BF28_5592 ENOG4105EKQ RNA-directed DNA polymerase BF28_5594 ENOG4105DQ6 Transposase BF28_5596 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BF28_5608 ENOG4105D7V transposase BF28_5611 ENOG4105D7V transposase BF28_5617 ENOG4107ZTW SNARE associated Golgi BF28_562 ENOG41067MG lrgb family BF28_5620 ENOG4107UVV polysaccharide deacetylase BF28_5621 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF28_563 ENOG4105XZU Preprotein translocase, subunit SecG BF28_5638 ENOG4105KVH Transcriptional regulator BF28_5639 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BF28_5640 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF28_5644 ENOG4105F0V Cell wall hydrolase BF28_565 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BF28_5651 ENOG4105E1K spore germination protein BF28_5663 ENOG4108QY0 Membrane BF28_5690 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BF28_5699 ENOG4105F6J Alpha beta hydrolase fold BF28_570 ENOG4105CM4 permease protein BF28_5702 ENOG4105DUX Transporter BF28_5704 ENOG4105D7V transposase BF28_5705 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF28_5706 ENOG4108594 Permease of the drug metabolite transporter BF28_571 ENOG4108IPW abc transporter atp-binding protein BF28_5714 ENOG4107VMI polysaccharide deacetylase BF28_5716 ENOG4107A6P BF28_5721 ENOG4105MKU Transcriptional regulator BF28_5729 ENOG4107Y80 Major Facilitator superfamily BF28_5731 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF28_5744 ENOG4105DQ6 Transposase BF28_5749 ENOG4105DQ6 Transposase BF28_5750 ENOG4105C94 Transporter BF28_5753 ENOG4105D7V transposase BF28_5759 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF28_576 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BF28_577 ENOG4108MK9 spermidine N(1)-acetyltransferase BF28_5795 ENOG4108C33 Resolvase BF28_5800 ENOG4105EKQ RNA-directed DNA polymerase BF28_5826 ENOG4105D7V transposase BF28_5827 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BF28_583 ENOG4105C8Q Methyl-accepting chemotaxis BF28_5830 ENOG4105CHH sulfate transporter BF28_5854 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BF28_5855 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BF28_5857 ENOG4107TIF Phenazine biosynthesis protein, PhzF family BF28_5864 ENOG4108QY0 Membrane BF28_5868 ENOG4105D7V transposase BF28_5871 ENOG4105D7V transposase BF28_5874 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF28_5882 ENOG4105D7V transposase BF28_5889 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BF28_589 ENOG4105KVH Transcriptional regulator BF28_5893 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme BF28_5896 ENOG4105D4Y metalloprotease BF28_5897 ENOG4105C8Q Methyl-accepting chemotaxis BF28_590 ENOG4105F27 Major Facilitator BF28_5900 ENOG4107SDU Methyl-accepting chemotaxis BF28_5908 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BF28_5909 ENOG4105CSC Glucose uptake protein BF28_591 ENOG4105CV8 reductase BF28_5910 ENOG4105FBA Phospholipase Carboxylesterase BF28_5911 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BF28_5912 ENOG4107XWI flavin reductase domain protein, FMN-binding BF28_5913 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BF28_5914 ENOG41090MY MarR family Transcriptional regulator BF28_5920 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BF28_5921 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BF28_5922 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BF28_5923 ENOG4108R6W Transcriptional regulator, ARAC family BF28_5924 ENOG4106AM8 polysaccharide lyase family 8 BF28_5926 ENOG4105EP8 Glycosyl Hydrolase Family 88 BF28_5927 ENOG4108EQA pts system BF28_5928 ENOG4105F3R pts system mannose fructose sorbose family iid BF28_5929 ENOG4105ETZ PTS System BF28_5931 ENOG4105CHR reductase BF28_5932 ENOG4105D50 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity) BF28_5933 ENOG4105D7K pfkb domain protein BF28_5935 ENOG4106P37 HTH-type transcriptional regulator YjhI BF28_5937 ENOG4107K5X Membrane-bound metal-dependent hydrolase BF28_5939 ENOG410780I phosphoprotein phosphatase activity BF28_594 ENOG4108RYK Nad-dependent epimerase dehydratase BF28_5940 ENOG4105D7V transposase BF28_5943 ENOG4108Z5V transcriptional regulator, merr family BF28_5946 ENOG4105DQ6 Transposase BF28_5950 ENOG4107QJE Chromosome Partitioning Protein BF28_597 ENOG4105D9N nucleoside BF28_5973 ENOG4105KRN Transcriptional regulator, abrb family BF28_5979 ENOG4105DQ6 Transposase BF28_598 ENOG4105D9N nucleoside BF28_5981 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF28_5984 ENOG4107TSN permease BF28_5989 ENOG4105DSE periplasmic solute binding protein BF28_5990 ENOG4105CC5 ABC transporter BF28_5991 ENOG4105DIK (ABC) transporter BF28_6019 ENOG41067QW Transcriptional regulator BF28_602 ENOG4108URH decarboxylase BF28_6029 ENOG4105E09 nadh pyrophosphatase BF28_605 ENOG4108RMU ferritin dps family protein BF28_607 ENOG4105NCW Trka-c domain protein BF28_608 ENOG4107S91 Sodium hydrogen exchanger BF28_612 ENOG4105D4Y metalloprotease BF28_613 ENOG4105VG1 fes assembly suf system protein BF28_614 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF28_615 ENOG4105C8Q Methyl-accepting chemotaxis BF28_619 ENOG4105BZU Histidine kinase BF28_620 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_621 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BF28_623 ENOG4107ZTW SNARE associated Golgi BF28_629 ENOG4105CJ1 ABC, transporter BF28_631 ENOG4108TU7 Inherit from COG: (ABC) transporter BF28_632 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_633 ENOG4105BZU Histidine kinase BF28_636 ENOG4107AYK membrAne BF28_638 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF28_64 ENOG4105XPM ribosomal protein BF28_641 ENOG4107R7I amino acid BF28_642 ENOG4108SUT Major Facilitator Superfamily BF28_646 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF28_650 ENOG4105DZ1 carboxypeptidase BF28_653 ENOG4105CHU acetyl-coa acetyltransferase BF28_654 ENOG4105C1G acyl-Coa dehydrogenase BF28_655 ENOG4108W8B Beta-lactamase domain protein BF28_668 ENOG41080E8 Transcriptional regulator, Spx MgsR family BF28_67 ENOG4107Y49 methyltransferase BF28_674 ENOG4108UMI ABC transporter, permease BF28_675 ENOG4105D01 (LipO)protein BF28_676 ENOG4105D01 (LipO)protein BF28_677 ENOG4105C3K feS assembly ATPase SufC BF28_678 ENOG4105JRK feS assembly protein SufD BF28_679 ENOG4105C9B Cysteine desulfurase BF28_680 ENOG4108UNV SUF system FeS assembly protein, NifU family BF28_681 ENOG4105DIW FeS assembly protein SUFB BF28_682 ENOG4107R8B 5'-nucleotidase BF28_683 ENOG4105KZD Domain of unknown function (DUF1805) BF28_685 ENOG4105FAA peptidase M23 BF28_690 ENOG41090T1 Membrane BF28_691 ENOG4107TXC Transcriptional regulator BF28_692 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BF28_693 ENOG4105MMD transcriptional regulator BF28_696 ENOG4105CBT Fructose-1,6-bisphosphatase BF28_699 ENOG4105D4U had-superfamily hydrolase, subfamily iia BF28_701 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF28_703 ENOG4108W5N phosphatidylglycerophosphatase a BF28_706 ENOG41083MR nifu domain-containing protein BF28_710 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BF28_711 ENOG4105C4B ABC transporter, permease BF28_712 ENOG4108JJA ABC, transporter BF28_716 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BF28_719 ENOG4105EWC Purine nucleoside phosphorylase BF28_72 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BF28_725 ENOG4105CEP NADH dehydrogenase BF28_728 ENOG41069ER domain protein BF28_732 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF28_735 ENOG4105KA0 thioesterase Superfamily protein BF28_736 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BF28_739 ENOG4107R3E Citrate transporter BF28_74 ENOG4105QIV RNA polymerase BF28_741 ENOG4105Y38 Kinase-associated protein B BF28_744 ENOG4105C87 Aminotransferase class I and II BF28_746 ENOG4108MUZ hydrolase BF28_747 ENOG4105C5I Dehydrogenase BF28_748 ENOG4108ZB6 transcriptional regulator AsnC family BF28_749 ENOG4105CHM Aminotransferase BF28_75 ENOG4105M0M Tetracycline resistance protein BF28_751 ENOG4105WG9 Conserved Protein BF28_753 ENOG4107PBV potassium channel BF28_755 ENOG4105KT7 mgtC SapB transporter BF28_76 ENOG4105C2N RNA methyltransferase TrmH family group 3 BF28_763 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BF28_782 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF28_784 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BF28_787 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BF28_79 ENOG4105D7W serine acetyltransferase BF28_794 ENOG4105VEQ Cold shock protein BF28_796 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF28_797 ENOG4105E4F Isochorismate synthase BF28_799 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BF28_800 ENOG4108IPT Naphthoate synthase BF28_802 ENOG4105DTQ mandelate racemase muconate lactonizing BF28_806 ENOG4107Y2X deaminase BF28_808 ENOG4106P55 Transcriptional regulator BF28_809 ENOG41069H0 dihydroorotase EC 3.5.2.3 BF28_813 ENOG4105FDP GntR family transcriptional regulator BF28_814 ENOG4105C6Z Gluconate BF28_822 ENOG41082BM Transcriptional regulator, arsr family BF28_824 ENOG4105CJ1 ABC, transporter BF28_826 ENOG41086D8 Transcriptional regulator BF28_827 ENOG4105C19 ABC transporter BF28_83 ENOG4105CTP PilT protein domain protein BF28_832 ENOG4107ZTW SNARE associated Golgi BF28_838 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BF28_839 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF28_844 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF28_845 ENOG4105BZU Histidine kinase BF28_85 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BF28_851 ENOG41087YS Phage shock protein A BF28_860 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF28_861 ENOG4105C4M (Ubiquinol oxidase) subunit I BF28_863 ENOG4108V2W Carbonate dehydratase BF28_872 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BF28_874 ENOG4105D2X ABC transporter substrate-binding protein BF28_877 ENOG4107T7U Sulfatase BF28_878 ENOG4107S9D Alpha beta hydrolase BF28_879 ENOG4105BZU Histidine kinase BF28_88 ENOG4108Z0C Uvrb UvrC protein BF28_880 ENOG4105BZU Histidine kinase BF28_882 ENOG4105E98 transcriptional regulator DeoR family BF28_883 ENOG4107XGZ Hydrolase BF28_884 ENOG4105EGD dinuclear metal center protein, YbgI family BF28_892 ENOG4108MK9 spermidine N(1)-acetyltransferase BF28_895 ENOG4108RIR Molybdenum cofactor biosynthesis protein BF28_897 ENOG4105BZF Glycosyl transferase (Group 1 BF28_898 ENOG4105YVM Phosphoesterase, PA-phosphatase related BF28_899 ENOG4108Z0R Transferase BF28_900 ENOG4105E8V Alpha Beta Hydrolase Fold protein BF28_908 ENOG4105DA5 (ABC) transporter BF28_910 ENOG4105N5T Radical SAM Protein BF28_914 ENOG4105C19 ABC transporter BF28_917 ENOG4105NCW Trka-c domain protein BF28_918 ENOG4107S91 Sodium hydrogen exchanger BF28_919 ENOG410605W Major Facilitator BF28_925 ENOG4108B31 Spore germination protein BF28_927 ENOG4105DWV Homoserine O-trans-acetylase BF28_929 ENOG41085GJ domain protein BF28_933 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF28_934 ENOG4105D06 uba thif-type nad fad binding protein BF28_936 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF28_937 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BF28_938 ENOG4108ZAF Molybdopterin BF28_942 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BF28_943 ENOG4108VJ1 Transcriptional regulator (CarD family BF28_950 ENOG4105CBX hi0933 family BF28_953 ENOG4105YW5 deoR family transcriptional regulator BF28_954 ENOG4107QSE Dipeptidase BF28_956 ENOG4108IUM Glycogen debranching enzyme BF28_957 ENOG4108V15 phosphotransferase enzyme family BF28_960 ENOG4105C8F Beta-lactamase domain protein BF28_966 ENOG4108VDD TRNA binding domain protein BF28_972 ENOG4105K7K Transcriptional regulator BF28_977 ENOG4105C88 aminopeptidase BF28_982 ENOG4105ETE Transcriptional regulator (LacI family BF28_988 ENOG4105EP9 oxidoreductase BF28_989 ENOG4107SNB ankyrin repeat protein YahD BF28_991 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF28_993 ENOG4106HB6 Alpha beta hydrolase BF28_994 ENOG4105DGU Histone deacetylase BF28_995 ENOG4105W87 Cbs domain BF28_996 ENOG4105F1V Acetoin utilization protein BF28_999 ENOG4105EMN RNA polymerase sigma factor