locus-tag	class	description
BF28_1	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF28_1001	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF28_1011	COG0626	cystathionine gamma-synthase activity
BF28_1012	COG1956	GAF domain-containing protein
BF28_1013	COG1309	transcriptional regulator
BF28_1014	COG0697	spore germination
BF28_1015	COG0583	DNA-binding transcription factor activity
BF28_1017	COG1104	cysteine desulfurase activity
BF28_1020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_1022	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF28_1023	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF28_1025	COG3874	Sporulation protein YtfJ
BF28_1026	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF28_1027	COG0827	DNA restriction-modification system
BF28_1031	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_1040	COG0589	response to stress
BF28_1041	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_1044	COG1476	TRANSCRIPTIONal
BF28_1046	COG0662	Cupin 2, conserved barrel domain protein
BF28_1054	COG0006	proline dipeptidase activity
BF28_1057	COG4109	DRTGG domain
BF28_1059	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_1062	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF28_1065	COG0587	DNA-directed DNA polymerase activity
BF28_1066	COG0281	malic enzyme
BF28_1067	COG1725	Transcriptional regulator
BF28_1072	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF28_1073	COG0628	permease
BF28_1075	COG0372	Belongs to the citrate synthase family
BF28_1076	COG0538	isocitrate dehydrogenase activity
BF28_108	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF28_1081	COG0745	RESPONSE REGULATOR receiver
BF28_1082	COG5002	protein histidine kinase activity
BF28_1083	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_1083	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_1084	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF28_1085	COG1971	Probably functions as a manganese efflux pump
BF28_1087	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF28_1089	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF28_109	COG1396	sequence-specific DNA binding
BF28_1091	COG3611	Membrane attachment protein
BF28_1092	COG1484	DNA-dependent DNA replication
BF28_1094	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF28_1095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF28_1099	COG1363	Peptidase, m42
BF28_110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF28_1100	COG1309	transcriptional regulator
BF28_1101	COG1566	PFAM secretion protein HlyD family protein
BF28_1102	COG2814	Major facilitator Superfamily
BF28_1105	COG1418	mRNA catabolic process
BF28_1107	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF28_111	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF28_1110	COG0017	Asparaginyl-tRNA synthetase
BF28_1116	COG1286	toxin biosynthetic process
BF28_1117	COG1796	DNA polymerase
BF28_1117	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF28_112	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF28_1120	COG1187	pseudouridine synthase activity
BF28_1121	COG1114	Component of the transport system for branched-chain amino acids
BF28_1122	COG5386	Cell surface protein
BF28_1123	COG5386	Cell surface protein
BF28_1126	COG1120	ATPase activity
BF28_1127	COG4509	Sortase family
BF28_113	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_1130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF28_1131	COG4895	conserved protein (DUF2196)
BF28_1133	COG0745	RESPONSE REGULATOR receiver
BF28_1134	COG2205	protein histidine kinase activity
BF28_1135	COG1131	(ABC) transporter
BF28_114	COG0512	Glutamine amidotransferase of anthranilate synthase
BF28_1140	COG2318	DinB family
BF28_1142	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_1143	COG1309	transcriptional regulator
BF28_1144	COG1024	Enoyl-CoA hydratase
BF28_1145	COG2086	electron transfer activity
BF28_1146	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF28_1147	COG3118	belongs to the thioredoxin family
BF28_1149	COG1719	4-vinyl reductase, 4VR
BF28_115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF28_1150	COG2009	succinate dehydrogenase
BF28_1151	COG1053	succinate dehydrogenase
BF28_1152	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF28_1153	COG0824	Thioesterase
BF28_1154	COG1876	peptidase activity
BF28_1155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF28_1156	COG1360	Flagellar Motor Protein
BF28_1157	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF28_1158	COG4152	abc transporter atp-binding protein
BF28_1159	COG1668	transmembrane transport
BF28_116	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_1160	COG1959	2 iron, 2 sulfur cluster binding
BF28_1162	COG0697	spore germination
BF28_1163	COG1396	sequence-specific DNA binding
BF28_1164	COG1983	PspC domain protein
BF28_1166	COG3279	Response regulator of the LytR AlgR family
BF28_1167	COG3275	phosphorelay sensor kinase activity
BF28_1168	COG4608	Belongs to the ABC transporter superfamily
BF28_1169	COG0444	Belongs to the ABC transporter superfamily
BF28_1173	COG0402	S-adenosylhomocysteine deaminase activity
BF28_1174	COG0402	S-adenosylhomocysteine deaminase activity
BF28_1176	COG2233	PERMEase
BF28_1177	COG2197	response regulator
BF28_1180	COG5401	PFAM Sporulation and spore germination
BF28_1182	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF28_1183	COG0622	Phosphoesterase
BF28_1186	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BF28_119	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF28_1205	COG1067	ATP-dependent peptidase activity
BF28_1205	COG0470	DNA polymerase III
BF28_1208	COG1764	response to oxidative stress
BF28_1209	COG1846	Transcriptional regulator
BF28_1211	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF28_1213	COG1587	Uroporphyrinogen-III synthase
BF28_1214	COG0113	porphobilinogen synthase activity
BF28_1216	COG1388	LysM domain
BF28_1219	COG0285	dihydrofolate synthase activity
BF28_122	COG2208	phosphoserine phosphatase activity
BF28_1223	COG1077	Cell shape determining protein MreB Mrl
BF28_1224	COG1792	Involved in formation and maintenance of cell shape
BF28_1227	COG2894	cell division
BF28_1228	COG0739	heme binding
BF28_1229	COG1994	Peptidase M50
BF28_1230	COG1530	ribonuclease E activity
BF28_1232	COG2868	ribosomal protein
BF28_1234	COG3290	protein histidine kinase activity
BF28_1236	COG0745	RESPONSE REGULATOR receiver
BF28_1237	COG5002	protein histidine kinase activity
BF28_1238	COG1136	(ABC) transporter
BF28_1239	COG0577	efflux transmembrane transporter activity
BF28_1240	COG0577	efflux transmembrane transporter activity
BF28_1241	COG0077	Prephenate dehydratase
BF28_1242	COG2258	MOSC domain
BF28_1243	COG1827	regulation of RNA biosynthetic process
BF28_1244	COG1104	cysteine desulfurase activity
BF28_1245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF28_1246	COG0157	Belongs to the NadC ModD family
BF28_125	COG1098	S1 RNA binding domain
BF28_1251	COG0640	Transcriptional regulator
BF28_1252	COG0697	spore germination
BF28_1254	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF28_1260	COG1862	Preprotein translocase
BF28_1262	COG2323	membrane
BF28_1263	COG2244	polysaccharide biosynthetic process
BF28_1265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF28_1265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF28_1266	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF28_1267	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF28_1267	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF28_1269	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF28_1274	COG0124	histidyl-tRNA synthetase
BF28_1276	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF28_1278	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF28_1279	COG1959	2 iron, 2 sulfur cluster binding
BF28_1280	COG1104	cysteine desulfurase activity
BF28_1283	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF28_1287	COG0628	permease
BF28_129	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF28_1290	COG4472	Bacterial protein of unknown function (DUF965)
BF28_1293	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF28_1299	COG0768	penicillin binding
BF28_130	COG3956	TIGRFAM MazG family protein
BF28_1304	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_1305	COG0626	cystathionine gamma-synthase activity
BF28_1306	COG1454	alcohol dehydrogenase
BF28_1306	COG1012	belongs to the aldehyde dehydrogenase family
BF28_1308	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF28_131	COG2244	polysaccharide biosynthetic process
BF28_1316	COG2259	Doxx family
BF28_1317	COG2514	catechol 2,3-dioxygenase activity
BF28_1319	COG3186	Phenylalanine-4-hydroxylase
BF28_132	COG2002	toxin-antitoxin pair type II binding
BF28_1320	COG1404	Belongs to the peptidase S8 family
BF28_1327	COG2267	carboxylic ester hydrolase activity
BF28_1329	COG1785	Belongs to the alkaline phosphatase family
BF28_133	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF28_1331	COG2357	RelA SpoT domain protein
BF28_1332	COG0778	Nitroreductase
BF28_1334	COG1595	DNA-templated transcription, initiation
BF28_1336	COG2801	Transposase and inactivated derivatives
BF28_1338	COG1191	sigma factor activity
BF28_1341	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF28_1342	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF28_1344	COG1534	Rna-binding protein
BF28_1346	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF28_1347	COG0799	negative regulation of ribosome biogenesis
BF28_1348	COG2226	methyltransferase
BF28_1349	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_1350	COG1596	polysaccharide export
BF28_1350	COG1555	photosystem II stabilization
BF28_1351	COG2131	deaminase
BF28_1352	COG0658	competence protein
BF28_1352	COG2333	competence protein COMEC
BF28_1354	COG1466	dna polymerase III delta subunit
BF28_1359	COG1733	regulation of RNA biosynthetic process
BF28_136	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF28_1360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF28_1362	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF28_1366	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF28_1367	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF28_1369	COG1610	YqeY-like protein
BF28_1372	COG1702	phosphate starvation-inducible protein PhoH
BF28_1373	COG1480	7TM receptor with intracellular HD hydrolase
BF28_1375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF28_1376	COG0295	cytidine deaminase activity
BF28_1377	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF28_1380	COG0517	IMP dehydrogenase activity
BF28_1382	COG0358	DNA primase activity
BF28_1383	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF28_1384	COG2010	Cytochrome c
BF28_1385	COG2384	SAM-dependent methyltransferase
BF28_1386	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF28_139	COG0251	oxidation-reduction process
BF28_1392	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_1393	COG1121	(ABC) transporter
BF28_1394	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF28_1395	COG0735	belongs to the Fur family
BF28_140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF28_1400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_1401	COG0477	Major facilitator Superfamily
BF28_1403	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF28_1404	COG0573	inorganic phosphate transmembrane transporter activity
BF28_1405	COG0581	inorganic phosphate transmembrane transporter activity
BF28_1406	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF28_1407	COG0704	Plays a role in the regulation of phosphate uptake
BF28_1408	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF28_1410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF28_1411	COG4483	Protein conserved in bacteria
BF28_1412	COG1940	carbohydrate kinase activity
BF28_1414	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_1418	COG0626	cystathionine gamma-synthase activity
BF28_1419	COG0626	cystathionine gamma-synthase activity
BF28_1420	COG0646	methionine synthase
BF28_1420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF28_1421	COG1410	methionine synthase
BF28_1421	COG0646	methionine synthase
BF28_143	COG4466	Protein conserved in bacteria
BF28_1431	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF28_1432	COG1459	type II secretion system
BF28_1434	COG4970	Tfp pilus assembly protein FimT
BF28_1445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_1451	COG1725	Transcriptional regulator
BF28_1452	COG1131	(ABC) transporter
BF28_1459	COG2076	Multidrug Resistance protein
BF28_146	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF28_1460	COG2076	Multidrug Resistance protein
BF28_1462	COG1609	Transcriptional regulator
BF28_1464	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_1465	COG0095	Lipoate-protein ligase
BF28_147	COG0084	hydrolase, TatD family'
BF28_1472	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF28_1473	COG3872	metal-dependent enzyme
BF28_1476	COG0006	proline dipeptidase activity
BF28_148	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_148	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_1481	COG3854	ATPases associated with a variety of cellular activities
BF28_149	COG2002	toxin-antitoxin pair type II binding
BF28_1490	COG0511	ligase activity, forming carbon-carbon bonds
BF28_1491	COG0439	Biotin carboxylase
BF28_1492	COG1302	Protein conserved in bacteria
BF28_1497	COG0142	geranyltranstransferase activity
BF28_1499	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF28_150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF28_1501	COG0497	DNA recombination
BF28_1502	COG0750	zinc metalloprotease
BF28_1503	COG0745	RESPONSE REGULATOR receiver
BF28_1507	COG3093	addiction module antidote protein HigA
BF28_1508	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_1510	COG3290	protein histidine kinase activity
BF28_1510	COG3829	transcription factor binding
BF28_1511	COG0280	phosphate acetyltransferase
BF28_1512	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF28_1514	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF28_1515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_1516	COG0022	dehydrogenase e1 component
BF28_1517	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_1518	COG0772	Belongs to the SEDS family
BF28_1519	COG2323	membrane
BF28_152	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF28_1523	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_1524	COG0765	amino acid transport
BF28_1525	COG1126	abc transporter atp-binding protein
BF28_1526	COG4129	membrane
BF28_1527	COG1376	ErfK ybiS ycfS ynhG family protein
BF28_1529	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_1530	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF28_1534	COG1760	l-serine dehydratase
BF28_1535	COG1760	l-serine dehydratase
BF28_1536	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_1537	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_1538	COG0300	oxidoreductase activity
BF28_154	COG1774	PSP1 C-terminal conserved region
BF28_1543	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF28_1547	COG1522	sequence-specific DNA binding
BF28_1549	COG0737	Belongs to the 5'-nucleotidase family
BF28_155	COG0470	DNA polymerase III
BF28_1552	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_1555	COG1073	alpha beta
BF28_1555	COG2226	methyltransferase
BF28_1556	COG4106	trans-aconitate 2-methyltransferase activity
BF28_1557	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF28_1561	COG0307	riboflavin synthase, alpha
BF28_1562	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_1562	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_1565	COG1073	alpha beta
BF28_1566	COG0456	acetyltransferase
BF28_1567	COG1609	Transcriptional regulator
BF28_1568	COG2056	Na+-H+ antiporter family
BF28_1569	COG0596	Alpha beta hydrolase
BF28_157	COG1982	Orn Lys Arg decarboxylase major
BF28_1571	COG4085	toxin activity
BF28_1571	COG1525	nuclease
BF28_1571	COG0737	Belongs to the 5'-nucleotidase family
BF28_1573	COG0456	acetyltransferase
BF28_1573	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF28_1574	COG0656	L-ascorbic acid biosynthetic process
BF28_1575	COG0667	Aldo Keto reductase
BF28_1579	COG1300	Membrane
BF28_1580	COG0735	belongs to the Fur family
BF28_1582	COG4974	Belongs to the 'phage' integrase family
BF28_1587	COG0598	Magnesium transport protein CorA
BF28_1590	COG1846	Transcriptional regulator
BF28_1594	COG1131	(ABC) transporter
BF28_1595	COG1725	Transcriptional regulator
BF28_1596	COG1686	Belongs to the peptidase S11 family
BF28_1600	COG0733	neurotransmitter:sodium symporter activity
BF28_1605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_1608	COG0697	spore germination
BF28_1609	COG0561	phosphatase activity
BF28_1610	COG4086	secreted protein
BF28_1611	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF28_1612	COG0456	acetyltransferase
BF28_1613	COG1547	Domain of unknown function (DUF309)
BF28_1618	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF28_1622	COG3711	transcriptional antiterminator
BF28_1623	COG1263	PTS System
BF28_1623	COG2190	(PTS) system
BF28_1623	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_1628	COG0778	Nitroreductase
BF28_1629	COG3706	GGDEF domain
BF28_1630	COG2084	Dehydrogenase
BF28_1637	COG0436	Aminotransferase
BF28_1638	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF28_1642	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_1643	COG1695	Transcriptional regulator
BF28_1650	COG0183	Belongs to the thiolase family
BF28_1658	COG3842	ATPase activity
BF28_1659	COG0366	Alpha amylase catalytic
BF28_1661	COG2182	Extracellular solute-binding protein
BF28_1662	COG1175	transmembrane transport
BF28_1663	COG3833	ABC-type maltose transport systems, permease component
BF28_1664	COG1609	Transcriptional regulator
BF28_1665	COG0436	Aminotransferase
BF28_1667	COG2205	protein histidine kinase activity
BF28_1669	COG3209	COG3209 Rhs family protein
BF28_167	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF28_1673	COG2814	Major facilitator Superfamily
BF28_168	COG0590	tRNA wobble adenosine to inosine editing
BF28_1680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF28_1682	COG1408	metallophosphoesterase
BF28_1683	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_1684	COG2200	EAL domain
BF28_1687	COG4703	Protein of unknown function (DUF1797)
BF28_1689	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF28_169	COG1335	isochorismatase
BF28_1691	COG0517	IMP dehydrogenase activity
BF28_1692	COG0583	DNA-binding transcription factor activity
BF28_1696	COG0569	domain protein
BF28_1697	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_1699	COG0561	phosphatase activity
BF28_170	COG1428	Deoxynucleoside kinase
BF28_1700	COG0242	peptide deformylase activity
BF28_1702	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_1703	COG0022	dehydrogenase e1 component
BF28_171	COG1428	Deoxynucleoside kinase
BF28_1713	COG1982	Orn Lys Arg decarboxylase major
BF28_1717	COG0483	inositol monophosphate 1-phosphatase activity
BF28_1722	COG4896	Protein conserved in bacteria
BF28_1724	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF28_1725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF28_1727	COG0772	Belongs to the SEDS family
BF28_1728	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF28_1735	COG3336	cytochrome c oxidase
BF28_1738	COG2340	Cysteine-rich secretory protein family
BF28_1741	COG0406	alpha-ribazole phosphatase activity
BF28_1742	COG3679	Belongs to the UPF0342 family
BF28_1745	COG0742	ribosomal rna small subunit methyltransferase
BF28_1746	COG3314	Sporulation integral membrane protein YlbJ
BF28_1748	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF28_1749	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF28_1751	COG1399	metal-binding, possibly nucleic acid-binding protein
BF28_1755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF28_1758	COG4839	cell division protein FtsL
BF28_1760	COG0768	penicillin binding
BF28_1761	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF28_1764	COG0772	Belongs to the SEDS family
BF28_1765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF28_1767	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF28_1768	COG0849	cell division
BF28_1769	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF28_177	COG1686	Belongs to the peptidase S11 family
BF28_1771	COG1191	sigma factor activity
BF28_1772	COG1191	sigma factor activity
BF28_1773	COG1873	PFAM PRC-barrel domain
BF28_1775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF28_1777	COG0762	integral membrane protein
BF28_1778	COG2302	S4 RNA-binding domain
BF28_1779	COG3599	regulation of cell shape
BF28_178	COG0516	GMP reductase activity
BF28_178	COG0517	IMP dehydrogenase activity
BF28_1783	COG0564	pseudouridine synthase activity
BF28_1795	COG3069	C4-dicarboxylate transmembrane transporter activity
BF28_1799	COG0006	proline dipeptidase activity
BF28_18	COG0726	polysaccharide deacetylase
BF28_1801	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF28_1802	COG1561	YicC-like family, N-terminal region
BF28_1804	COG0194	GDP metabolic process
BF28_1806	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF28_1807	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF28_1808	COG0242	peptide deformylase activity
BF28_1810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF28_1810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF28_1812	COG0631	protein serine/threonine phosphatase activity
BF28_1813	COG0515	serine threonine protein kinase
BF28_1813	COG2815	serine threonine protein kinase
BF28_1815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF28_1816	COG1564	THIamine pyrophosphokinase
BF28_1818	COG1302	Protein conserved in bacteria
BF28_1819	COG1461	Dihydroxyacetone kinase
BF28_1820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF28_1823	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF28_1824	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_1827	COG1196	nuclear chromosome segregation
BF28_1828	COG0552	protein localization to endoplasmic reticulum
BF28_1830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF28_1832	COG1837	Belongs to the UPF0109 family
BF28_1840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF28_1841	COG0758	DNA mediated transformation
BF28_1842	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF28_1844	COG4974	Belongs to the 'phage' integrase family
BF28_1850	COG0528	UMP kinase activity
BF28_1853	COG4589	Belongs to the CDS family
BF28_1854	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF28_1855	COG0750	zinc metalloprotease
BF28_1859	COG0195	Participates in both transcription termination and antitermination
BF28_186	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF28_1860	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF28_1861	COG1358	cellular component organization or biogenesis
BF28_1863	COG1550	Protein conserved in bacteria
BF28_1866	COG0196	riboflavin kinase activity
BF28_1869	COG0726	polysaccharide deacetylase
BF28_187	COG0187	DNA topoisomerase II activity
BF28_1870	COG0612	Peptidase, M16
BF28_1871	COG1873	PFAM PRC-barrel domain
BF28_1872	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF28_1873	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF28_1874	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF28_1875	COG0527	aspartate kinase activity
BF28_1877	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_1878	COG0740	serine-type endopeptidase activity
BF28_1880	COG1674	ftsk spoiiie
BF28_1881	COG2188	Transcriptional regulator
BF28_1886	COG0612	Peptidase, M16
BF28_1887	COG0612	Peptidase, M16
BF28_1888	COG0300	oxidoreductase activity
BF28_189	COG2501	S4 domain
BF28_1891	COG1426	Protein conserved in bacteria
BF28_1892	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF28_1897	COG1692	metallophosphoesterase
BF28_1898	COG2359	stage V sporulation protein S
BF28_19	COG2194	sulfuric ester hydrolase activity
BF28_190	COG0592	DNA-directed DNA polymerase activity
BF28_1900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF28_1900	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF28_1901	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF28_1903	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF28_1907	COG0640	Transcriptional regulator
BF28_1910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF28_1916	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_1917	COG1368	sulfuric ester hydrolase activity
BF28_1918	COG0562	UDP-galactopyranose mutase
BF28_1919	COG3773	Cell wall hydrolase
BF28_1920	COG1404	Belongs to the peptidase S8 family
BF28_1923	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_1924	COG1380	Effector of murein hydrolase LrgA
BF28_1927	COG3300	MHYT domain
BF28_1927	COG5001	Diguanylate cyclase
BF28_1928	COG0346	lactoylglutathione lyase activity
BF28_1932	COG2364	Membrane
BF28_1934	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF28_1935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF28_1936	COG2169	Transcriptional regulator
BF28_1937	COG0708	Exodeoxyribonuclease III
BF28_1938	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_1939	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_194	COG0706	membrane insertase activity
BF28_1940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_1941	COG1120	ATPase activity
BF28_1942	COG2819	hydrolase of the alpha beta superfamily
BF28_1944	COG1937	Protein conserved in bacteria
BF28_1945	COG2608	mercury ion transmembrane transporter activity
BF28_1946	COG2217	Heavy metal translocating P-type atpase
BF28_1948	COG2116	formate transmembrane transporter activity
BF28_1949	COG1408	metallophosphoesterase
BF28_195	COG1847	R3H domain protein
BF28_1951	COG1113	amino acid transport
BF28_1954	COG2322	membrane
BF28_1955	COG1979	alcohol dehydrogenase
BF28_1956	COG1349	DNA-binding transcription factor activity
BF28_1957	COG1105	Belongs to the carbohydrate kinase PfkB family
BF28_1958	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF28_1958	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_1958	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF28_1959	COG1388	LysM domain
BF28_1959	COG3584	3D domain protein
BF28_1965	COG0464	growth
BF28_1967	COG2860	membrane
BF28_1968	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF28_1969	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF28_1970	COG0789	Transcriptional regulator
BF28_1971	COG0174	glutamine synthetase
BF28_1990	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF28_1997	COG1595	DNA-templated transcription, initiation
BF28_200	COG1192	Involved in chromosome partitioning
BF28_201	COG1475	DNA binding
BF28_2029	COG1122	ATPase activity
BF28_203	COG0668	transmembrane transport
BF28_2036	COG1695	Transcriptional regulator
BF28_204	COG4481	Protein conserved in bacteria
BF28_2040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF28_2042	COG0737	Belongs to the 5'-nucleotidase family
BF28_2045	COG3639	organic phosphonate transmembrane transporter activity
BF28_205	COG0012	GTP binding
BF28_2050	COG1132	(ABC) transporter
BF28_2051	COG1132	(ABC) transporter
BF28_2054	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF28_2054	COG3409	Peptidoglycan-binding domain 1 protein
BF28_2057	COG0730	response to heat
BF28_2060	COG1346	cytolysis
BF28_2062	COG0583	DNA-binding transcription factor activity
BF28_2064	COG1131	(ABC) transporter
BF28_2069	COG0785	Cytochrome C biogenesis protein
BF28_207	COG0629	single-stranded DNA binding
BF28_2070	COG4846	Membrane protein involved in cytochrome C biogenesis
BF28_2078	COG2226	methyltransferase
BF28_2083	COG0010	Belongs to the arginase family
BF28_2084	COG1329	Transcriptional regulator
BF28_2085	COG1902	pentaerythritol trinitrate reductase activity
BF28_2086	COG0069	glutamate synthase activity
BF28_2087	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_2088	COG0346	lactoylglutathione lyase activity
BF28_2089	COG0400	carboxylic ester hydrolase activity
BF28_209	COG4241	membrane
BF28_2090	COG5002	protein histidine kinase activity
BF28_2092	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_21	COG0489	protein tyrosine kinase activity
BF28_210	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF28_2101	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_2102	COG1268	BioY protein
BF28_2103	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_2104	COG0183	Belongs to the thiolase family
BF28_2107	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF28_2109	COG2211	Major facilitator Superfamily
BF28_2113	COG0726	polysaccharide deacetylase
BF28_2115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF28_2116	COG1132	(ABC) transporter
BF28_2118	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_212	COG0305	Participates in initiation and elongation during chromosome replication
BF28_2124	COG0824	Thioesterase
BF28_2125	COG4841	protein insertion into membrane
BF28_2129	COG0745	RESPONSE REGULATOR receiver
BF28_2130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_2131	COG1832	CoA-binding protein
BF28_2132	COG0187	DNA topoisomerase II activity
BF28_2133	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF28_2134	COG0673	inositol 2-dehydrogenase activity
BF28_2136	COG1131	(ABC) transporter
BF28_2138	COG1595	DNA-templated transcription, initiation
BF28_2140	COG1316	TRANSCRIPTIONal
BF28_2141	COG1301	dicarboxylic acid transport
BF28_2142	COG4166	transmembrane transport
BF28_2143	COG4166	transmembrane transport
BF28_2144	COG4166	transmembrane transport
BF28_2145	COG2226	methyltransferase
BF28_2154	COG0697	spore germination
BF28_2155	COG3383	formate dehydrogenase (NAD+) activity
BF28_2156	COG2427	Protein of unknown function (DUF1641)
BF28_2157	COG5609	conserved protein (DUF2294)
BF28_2158	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF28_2160	COG2116	formate transmembrane transporter activity
BF28_2161	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_2162	COG0303	'Molybdopterin
BF28_2163	COG0314	molybdopterin synthase activity
BF28_2165	COG0489	protein tyrosine kinase activity
BF28_2168	COG3326	Membrane
BF28_2169	COG2962	Rard protein
BF28_2170	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF28_2171	COG1657	PFAM Prenyltransferase squalene oxidase
BF28_2173	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_2174	COG1012	belongs to the aldehyde dehydrogenase family
BF28_2176	COG4145	pantothenate transmembrane transporter activity
BF28_2179	COG0165	Argininosuccinate lyase
BF28_218	COG0745	RESPONSE REGULATOR receiver
BF28_2181	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_2187	COG0716	FMN binding
BF28_2189	COG1278	Cold shock
BF28_219	COG5002	protein histidine kinase activity
BF28_2194	COG2720	vancomycin resistance protein
BF28_2195	COG2514	catechol 2,3-dioxygenase activity
BF28_2198	COG1285	pathogenesis
BF28_22	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_220	COG4863	YycH protein
BF28_2200	COG1024	Enoyl-CoA hydratase
BF28_2201	COG1216	Glycosyl transferase, family 2
BF28_2207	COG0277	FAD linked oxidase domain protein
BF28_2208	COG0385	Bile acid
BF28_221	COG4853	Protein conserved in bacteria
BF28_2212	COG2808	Putative FMN-binding domain
BF28_2214	COG0457	Tetratricopeptide repeat
BF28_2216	COG0604	alcohol dehydrogenase
BF28_2217	COG0640	Transcriptional regulator
BF28_222	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF28_2222	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_2228	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_2229	COG1164	Oligoendopeptidase f
BF28_223	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_2230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF28_2231	COG1193	negative regulation of DNA recombination
BF28_2237	COG0583	DNA-binding transcription factor activity
BF28_2244	COG0384	phenazine biosynthesis protein PhzF
BF28_2245	COG3739	integral membrane protein
BF28_2246	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_2247	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_2248	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_2251	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_2252	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF28_2259	COG2814	Major facilitator Superfamily
BF28_2260	COG1113	amino acid transport
BF28_2261	COG0604	alcohol dehydrogenase
BF28_2264	COG0714	Associated with various cellular activities
BF28_2272	COG2072	flavoprotein involved in K transport
BF28_2274	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_2280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_2284	COG1151	hydroxylamine reductase activity
BF28_2289	COG3152	Membrane
BF28_229	COG1164	Oligoendopeptidase f
BF28_2298	COG1309	transcriptional regulator
BF28_2301	COG1191	sigma factor activity
BF28_2303	COG0726	polysaccharide deacetylase
BF28_2307	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_2308	COG1733	regulation of RNA biosynthetic process
BF28_2309	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_2310	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_2314	COG0384	phenazine biosynthesis protein PhzF
BF28_2318	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_2322	COG1733	regulation of RNA biosynthetic process
BF28_2323	COG1733	regulation of RNA biosynthetic process
BF28_2324	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF28_2325	COG0673	inositol 2-dehydrogenase activity
BF28_2326	COG2188	Transcriptional regulator
BF28_2327	COG1733	regulation of RNA biosynthetic process
BF28_2328	COG1393	Belongs to the ArsC family
BF28_2333	COG0814	amino acid
BF28_2334	COG0346	lactoylglutathione lyase activity
BF28_2337	COG2814	Major facilitator Superfamily
BF28_2338	COG0656	L-ascorbic acid biosynthetic process
BF28_234	COG1272	protein, Hemolysin III
BF28_2341	COG1733	regulation of RNA biosynthetic process
BF28_2343	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_2343	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_2346	COG0840	transmembrane signaling receptor activity
BF28_2349	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF28_2353	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_2354	COG0604	alcohol dehydrogenase
BF28_2355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF28_2356	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF28_2358	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF28_2359	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF28_2361	COG1070	Carbohydrate kinase
BF28_2362	COG2706	6-phosphogluconolactonase activity
BF28_2363	COG3813	Protein conserved in bacteria
BF28_2364	COG1357	PFAM Pentapeptide repeats (8 copies)
BF28_2365	COG0697	spore germination
BF28_2371	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF28_2373	COG0789	Transcriptional regulator
BF28_2374	COG1253	flavin adenine dinucleotide binding
BF28_2380	COG0477	Major facilitator Superfamily
BF28_2382	COG2226	methyltransferase
BF28_2386	COG0628	permease
BF28_2388	COG0180	Tryptophanyl-tRNA synthetase
BF28_239	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_2390	COG0577	efflux transmembrane transporter activity
BF28_2390	COG1136	(ABC) transporter
BF28_2392	COG0110	maltose O-acetyltransferase activity
BF28_2393	COG0738	Major facilitator superfamily
BF28_2394	COG0738	Major facilitator superfamily
BF28_2395	COG1940	carbohydrate kinase activity
BF28_2396	COG0346	lactoylglutathione lyase activity
BF28_240	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF28_2403	COG1011	Hydrolase
BF28_2408	COG1131	(ABC) transporter
BF28_241	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_2410	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_2414	COG0778	Nitroreductase
BF28_2415	COG1733	regulation of RNA biosynthetic process
BF28_2418	COG2197	response regulator
BF28_242	COG2814	Major facilitator Superfamily
BF28_2420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF28_2422	COG3620	sequence-specific DNA binding
BF28_2425	COG0789	Transcriptional regulator
BF28_243	COG3275	phosphorelay sensor kinase activity
BF28_2430	COG1288	antiporter activity
BF28_2434	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF28_244	COG3279	Response regulator of the LytR AlgR family
BF28_2441	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_2443	COG2031	fatty acid transporter
BF28_2447	COG2814	Major facilitator Superfamily
BF28_2448	COG1846	Transcriptional regulator
BF28_2450	COG0477	Major facilitator Superfamily
BF28_2458	COG2814	Major facilitator Superfamily
BF28_2461	COG3409	Peptidoglycan-binding domain 1 protein
BF28_2461	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF28_2467	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_2467	COG2207	Transcriptional regulator
BF28_2468	COG0662	Cupin 2, conserved barrel domain protein
BF28_247	COG0628	permease
BF28_2471	COG1595	DNA-templated transcription, initiation
BF28_2475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF28_2478	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_248	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_248	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_2483	COG0583	DNA-binding transcription factor activity
BF28_2485	COG1139	Iron-sulfur cluster binding protein
BF28_2486	COG1556	Lactate utilization protein
BF28_2487	COG2271	Major facilitator Superfamily
BF28_2488	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_2489	COG2808	Putative FMN-binding domain
BF28_249	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF28_2490	COG0456	acetyltransferase
BF28_2491	COG1846	Transcriptional regulator
BF28_2492	COG2364	Membrane
BF28_2494	COG5002	protein histidine kinase activity
BF28_2494	COG3850	Histidine kinase
BF28_2497	COG0577	efflux transmembrane transporter activity
BF28_250	COG1309	transcriptional regulator
BF28_2501	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF28_2502	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_2504	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_2505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_2508	COG1476	TRANSCRIPTIONal
BF28_251	COG0463	Glycosyl transferase, family 2
BF28_2512	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF28_2521	COG2814	Major facilitator Superfamily
BF28_2529	COG2169	Transcriptional regulator
BF28_2533	COG0346	lactoylglutathione lyase activity
BF28_2537	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_2539	COG0443	Heat shock 70 kDa protein
BF28_2543	COG0640	Transcriptional regulator
BF28_2544	COG0346	lactoylglutathione lyase activity
BF28_2545	COG0798	PFAM Bile acid sodium symporter
BF28_255	COG0488	(ABC) transporter
BF28_2551	COG0577	efflux transmembrane transporter activity
BF28_2552	COG1136	(ABC) transporter
BF28_2553	COG4641	Protein conserved in bacteria
BF28_2554	COG2267	carboxylic ester hydrolase activity
BF28_2559	COG1575	Belongs to the MenA family. Type 1 subfamily
BF28_2561	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_2564	COG1329	Transcriptional regulator
BF28_2569	COG5609	conserved protein (DUF2294)
BF28_2570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF28_2572	COG0288	reversible hydration of carbon dioxide
BF28_2578	COG0598	Magnesium transport protein CorA
BF28_2579	COG0753	catalase activity
BF28_258	COG1607	acyl-coa hydrolase
BF28_2580	COG0737	Belongs to the 5'-nucleotidase family
BF28_2581	COG0531	amino acid
BF28_2582	COG0534	Mate efflux family protein
BF28_2583	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_2583	COG0723	plastoquinol--plastocyanin reductase activity
BF28_2586	COG1115	amino acid carrier protein
BF28_2588	COG2066	Belongs to the glutaminase family
BF28_2589	COG4191	Histidine kinase
BF28_2590	COG0784	Response regulator, receiver
BF28_2591	COG0697	spore germination
BF28_2592	COG0531	amino acid
BF28_2594	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_2595	COG0531	amino acid
BF28_2596	COG0322	excinuclease ABC activity
BF28_2597	COG2801	Transposase and inactivated derivatives
BF28_2598	COG1396	sequence-specific DNA binding
BF28_2599	COG0252	asparaginase activity
BF28_26	COG0101	tRNA pseudouridine synthase activity
BF28_260	COG0840	transmembrane signaling receptor activity
BF28_2600	COG1027	Aspartate ammonia-lyase
BF28_2602	COG1136	(ABC) transporter
BF28_2605	COG0789	Transcriptional regulator
BF28_2607	COG1063	alcohol dehydrogenase
BF28_2613	COG1113	amino acid transport
BF28_2614	COG1280	lysine exporter protein (LysE YggA)
BF28_2615	COG3403	YqcI/YcgG family
BF28_2617	COG5577	PFAM Coat F domain
BF28_2620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_2622	COG0574	Belongs to the PEP-utilizing enzyme family
BF28_2622	COG3848	Pyruvate phosphate dikinase
BF28_2631	COG1960	acyl-CoA dehydrogenase activity
BF28_2633	COG0640	Transcriptional regulator
BF28_2634	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_2638	COG1414	Transcriptional regulator
BF28_2639	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF28_2640	COG1984	allophanate hydrolase subunit 2
BF28_265	COG0477	Major facilitator Superfamily
BF28_2653	COG4335	DNA alkylation repair
BF28_2655	COG0833	amino acid
BF28_2657	COG0730	response to heat
BF28_266	COG3279	Response regulator of the LytR AlgR family
BF28_2663	COG0596	Alpha beta hydrolase
BF28_2664	COG0745	RESPONSE REGULATOR receiver
BF28_2665	COG0642	Histidine kinase
BF28_2668	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_267	COG1966	Carbon starvation protein
BF28_2672	COG0456	acetyltransferase
BF28_2673	COG2207	Transcriptional regulator
BF28_2678	COG1136	(ABC) transporter
BF28_268	COG2879	small protein
BF28_2680	COG1725	Transcriptional regulator
BF28_2687	COG1846	Transcriptional regulator
BF28_2688	COG0778	Nitroreductase
BF28_269	COG3706	GGDEF domain
BF28_2690	COG0714	Associated with various cellular activities
BF28_2696	COG1280	lysine exporter protein (LysE YggA)
BF28_2698	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF28_2699	COG1846	Transcriptional regulator
BF28_27	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF28_270	COG0351	phosphomethylpyrimidine kinase
BF28_2702	COG1116	anion transmembrane transporter activity
BF28_2703	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_2704	COG0753	catalase activity
BF28_2705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF28_2707	COG0463	Glycosyl transferase, family 2
BF28_271	COG2203	Gaf domain
BF28_271	COG4585	Histidine kinase
BF28_2711	COG0463	Glycosyl transferase, family 2
BF28_2716	COG0714	Associated with various cellular activities
BF28_272	COG2197	response regulator
BF28_2721	COG0346	lactoylglutathione lyase activity
BF28_2726	COG3279	Response regulator of the LytR AlgR family
BF28_2728	COG4377	Putative membrane peptidase family (DUF2324)
BF28_2731	COG3655	Transcriptional regulator
BF28_2733	COG1785	Belongs to the alkaline phosphatase family
BF28_2734	COG3239	Fatty acid desaturase
BF28_2735	COG1690	Belongs to the RtcB family
BF28_2736	COG0833	amino acid
BF28_2737	COG1414	Transcriptional regulator
BF28_2738	COG4187	Peptidase family M20/M25/M40
BF28_2739	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_274	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF28_2742	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_2746	COG2329	Antibiotic biosynthesis monooxygenase
BF28_275	COG1011	Hydrolase
BF28_2754	COG1070	Carbohydrate kinase
BF28_2755	COG2390	Transcriptional regulator
BF28_2757	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF28_2759	COG1879	ABC-type sugar transport system periplasmic component
BF28_2766	COG1024	Enoyl-CoA hydratase
BF28_2767	COG2610	gluconate transmembrane transporter activity
BF28_2769	COG1388	LysM domain
BF28_2769	COG3584	3D domain protein
BF28_2776	COG1605	Chorismate mutase
BF28_2776	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF28_2779	COG0287	Prephenate dehydrogenase
BF28_278	COG0460	homoserine dehydrogenase
BF28_2782	COG1309	transcriptional regulator
BF28_2783	COG2409	Drug exporters of the RND superfamily
BF28_2783	COG1033	growth of symbiont in host cell
BF28_2786	COG0488	(ABC) transporter
BF28_2787	COG1368	sulfuric ester hydrolase activity
BF28_2788	COG0861	Integral membrane protein TerC family
BF28_2789	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_2791	COG3037	sugar-specific permease SgaT UlaA
BF28_2792	COG0726	polysaccharide deacetylase
BF28_2797	COG2318	DinB family
BF28_2798	COG0697	spore germination
BF28_280	COG1609	Transcriptional regulator
BF28_2802	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF28_281	COG2755	lipolytic protein G-D-S-L family
BF28_2812	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_2813	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_2814	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_2816	COG0628	permease
BF28_282	COG1131	(ABC) transporter
BF28_2826	COG1131	(ABC) transporter
BF28_283	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_2831	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF28_2832	COG0436	Aminotransferase
BF28_2839	COG2226	methyltransferase
BF28_2842	COG2261	transglycosylase associated protein
BF28_2846	COG0477	Major facilitator Superfamily
BF28_2846	COG2814	Major facilitator Superfamily
BF28_2847	COG4533	DNA binding
BF28_2848	COG0789	Transcriptional regulator
BF28_2849	COG1664	Polymer-forming cytoskeletal
BF28_285	COG2814	Major facilitator Superfamily
BF28_2851	COG2814	Major facilitator Superfamily
BF28_2858	COG1307	EDD domain protein, DegV family
BF28_286	COG0561	phosphatase activity
BF28_2861	COG1164	Oligoendopeptidase f
BF28_287	COG2233	PERMEase
BF28_2870	COG0745	RESPONSE REGULATOR receiver
BF28_2871	COG5002	protein histidine kinase activity
BF28_2872	COG2936	dipeptidyl-peptidase activity
BF28_288	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF28_2880	COG4948	Mandelate Racemase Muconate Lactonizing
BF28_2882	COG4166	transmembrane transport
BF28_2883	COG0519	Catalyzes the synthesis of GMP from XMP
BF28_2884	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF28_2887	COG0586	Pfam SNARE associated Golgi protein
BF28_2888	COG1078	dGTPase activity
BF28_2898	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_2899	COG3938	Belongs to the proline racemase family
BF28_290	COG2363	Small membrane protein
BF28_2901	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF28_2902	COG1012	belongs to the aldehyde dehydrogenase family
BF28_2903	COG1115	amino acid carrier protein
BF28_2904	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF28_2906	COG3397	chitin binding
BF28_2910	COG4637	Psort location Cytoplasmic, score
BF28_2914	COG0514	ATP-dependent DNA helicase (RecQ)
BF28_2915	COG2105	PFAM AIG2 family protein
BF28_2918	COG3973	AAA domain
BF28_292	COG3773	Cell wall hydrolase
BF28_2927	COG2333	competence protein COMEC
BF28_2927	COG0658	competence protein
BF28_2929	COG2315	Protein conserved in bacteria
BF28_2930	COG2226	methyltransferase
BF28_2931	COG2205	protein histidine kinase activity
BF28_2934	COG3397	chitin binding
BF28_2935	COG2153	protein acetylation
BF28_2936	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF28_2941	COG0517	IMP dehydrogenase activity
BF28_2941	COG4175	Glycine betaine
BF28_2942	COG4176	ABC-type proline glycine betaine transport system permease component
BF28_2947	COG0494	nUDIX hydrolase
BF28_2949	COG0572	uridine kinase
BF28_295	COG0280	phosphate acetyltransferase
BF28_2950	COG0456	acetyltransferase
BF28_2950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF28_2951	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_2953	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_2954	COG0022	dehydrogenase e1 component
BF28_2955	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_2956	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF28_296	COG0095	Lipoate-protein ligase
BF28_2960	COG1349	DNA-binding transcription factor activity
BF28_2961	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_2964	COG3284	Transcriptional regulator
BF28_2970	COG1309	transcriptional regulator
BF28_2976	COG3773	Cell wall hydrolase
BF28_2976	COG3409	Peptidoglycan-binding domain 1 protein
BF28_2977	COG2959	enzyme of heme biosynthesis
BF28_2980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_2987	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_2988	COG0697	spore germination
BF28_2990	COG0201	protein transport
BF28_2991	COG0346	lactoylglutathione lyase activity
BF28_2996	COG3227	Zinc metalloprotease (Elastase)
BF28_2997	COG1523	belongs to the glycosyl hydrolase 13 family
BF28_300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_3003	COG1011	Hydrolase
BF28_3008	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_301	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_3016	COG0322	excinuclease ABC activity
BF28_3019	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_302	COG1120	ATPase activity
BF28_3024	COG4667	esterase of the alpha-beta hydrolase superfamily
BF28_3028	COG3878	Protein conserved in bacteria
BF28_303	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_3031	COG1051	belongs to the nudix hydrolase family
BF28_3032	COG0592	DNA-directed DNA polymerase activity
BF28_3033	COG2816	NAD+ diphosphatase activity
BF28_3034	COG2223	nitrite transmembrane transporter activity
BF28_304	COG1078	dGTPase activity
BF28_3043	COG0697	spore germination
BF28_3044	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_3048	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_3052	COG2814	Major facilitator Superfamily
BF28_3054	COG2816	NAD+ diphosphatase activity
BF28_306	COG1994	Peptidase M50
BF28_3062	COG0693	protein deglycase activity
BF28_3073	COG0671	phosphoesterase, PA-phosphatase related
BF28_3074	COG0604	alcohol dehydrogenase
BF28_3077	COG2205	protein histidine kinase activity
BF28_308	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_3082	COG1794	racemase activity, acting on amino acids and derivatives
BF28_3083	COG1819	glycosyl
BF28_3085	COG5002	protein histidine kinase activity
BF28_3086	COG0561	phosphatase activity
BF28_309	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_3093	COG2124	cytochrome p450
BF28_310	COG0789	Transcriptional regulator
BF28_3102	COG5484	DNA packaging
BF28_3102	COG3728	DNA packaging
BF28_311	COG2814	Major facilitator Superfamily
BF28_3111	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF28_3113	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_3114	COG0460	homoserine dehydrogenase
BF28_3118	COG0577	efflux transmembrane transporter activity
BF28_3119	COG1136	(ABC) transporter
BF28_312	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF28_3124	COG2205	protein histidine kinase activity
BF28_3125	COG0745	RESPONSE REGULATOR receiver
BF28_3127	COG3773	Cell wall hydrolase
BF28_3128	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BF28_313	COG0010	Belongs to the arginase family
BF28_3130	COG3386	PFAM SMP-30 Gluconolaconase
BF28_3132	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF28_3133	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF28_3137	COG2323	membrane
BF28_3138	COG1063	alcohol dehydrogenase
BF28_3141	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_3150	COG2226	methyltransferase
BF28_3151	COG2814	Major facilitator Superfamily
BF28_3153	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_3159	COG3227	Zinc metalloprotease (Elastase)
BF28_316	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_3164	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF28_3168	COG1686	Belongs to the peptidase S11 family
BF28_3169	COG2318	DinB family
BF28_317	COG4506	Protein conserved in bacteria
BF28_3171	COG0572	uridine kinase
BF28_3172	COG1247	-acetyltransferase
BF28_3176	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_3177	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF28_3178	COG1024	Enoyl-CoA hydratase
BF28_3179	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF28_3180	COG0511	ligase activity, forming carbon-carbon bonds
BF28_3181	COG0439	Biotin carboxylase
BF28_3182	COG1960	acyl-CoA dehydrogenase activity
BF28_3185	COG1309	transcriptional regulator
BF28_3187	COG1131	(ABC) transporter
BF28_319	COG1595	DNA-templated transcription, initiation
BF28_3190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_3196	COG1309	transcriptional regulator
BF28_3200	COG1876	peptidase activity
BF28_3203	COG1476	TRANSCRIPTIONal
BF28_3204	COG0457	Tetratricopeptide repeat
BF28_3206	COG0737	Belongs to the 5'-nucleotidase family
BF28_3210	COG3718	enzyme involved in inositol metabolism
BF28_3216	COG0673	inositol 2-dehydrogenase activity
BF28_3217	COG2814	Major facilitator Superfamily
BF28_3218	COG1609	Transcriptional regulator
BF28_3219	COG0671	phosphoesterase, PA-phosphatase related
BF28_3220	COG2367	Beta-lactamase
BF28_3222	COG0768	penicillin binding
BF28_3224	COG1595	DNA-templated transcription, initiation
BF28_3228	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF28_323	COG2234	aminopeptidase activity
BF28_3235	COG1846	Transcriptional regulator
BF28_3236	COG3961	Belongs to the TPP enzyme family
BF28_3239	COG3615	Tellurite resistance protein tehB
BF28_3239	COG0500	methyltransferase
BF28_3240	COG0577	efflux transmembrane transporter activity
BF28_3240	COG1136	(ABC) transporter
BF28_3243	COG1309	transcriptional regulator
BF28_3247	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_325	COG0024	Methionine aminopeptidase
BF28_3251	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF28_3253	COG2971	BadF BadG BcrA BcrD
BF28_3258	COG1649	PFAM Uncharacterised BCR, COG1649
BF28_326	COG1131	(ABC) transporter
BF28_3263	COG1595	DNA-templated transcription, initiation
BF28_3266	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF28_327	COG0842	Transport permease protein
BF28_3273	COG1396	sequence-specific DNA binding
BF28_3277	COG1132	(ABC) transporter
BF28_3278	COG1132	(ABC) transporter
BF28_328	COG4585	Histidine kinase
BF28_3281	COG2258	MOSC domain
BF28_3282	COG0583	DNA-binding transcription factor activity
BF28_3285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF28_3286	COG0583	DNA-binding transcription factor activity
BF28_3287	COG2814	Major facilitator Superfamily
BF28_3288	COG1846	Transcriptional regulator
BF28_329	COG2197	response regulator
BF28_3290	COG0010	Belongs to the arginase family
BF28_3293	COG1278	Cold shock
BF28_3295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_3305	COG1247	-acetyltransferase
BF28_3312	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_3319	COG2226	methyltransferase
BF28_332	COG5001	Diguanylate cyclase
BF28_332	COG3300	MHYT domain
BF28_3321	COG0028	Belongs to the TPP enzyme family
BF28_3324	COG2814	Major facilitator Superfamily
BF28_3325	COG0596	Alpha beta hydrolase
BF28_3327	COG1136	(ABC) transporter
BF28_3328	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF28_3329	COG1187	pseudouridine synthase activity
BF28_3330	COG2329	Antibiotic biosynthesis monooxygenase
BF28_3333	COG1115	amino acid carrier protein
BF28_3335	COG2318	DinB family
BF28_3337	COG0776	regulation of translation
BF28_334	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_3340	COG2814	Major facilitator Superfamily
BF28_3342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF28_3343	COG3433	isochorismatase activity
BF28_3343	COG1535	isochorismatase
BF28_3344	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF28_3345	COG1169	isochorismate synthase
BF28_3346	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_3347	COG2223	nitrite transmembrane transporter activity
BF28_335	COG2181	nitrate reductase activity
BF28_335	COG0247	lactate metabolic process
BF28_3351	COG0419	ATPase involved in DNA repair
BF28_3352	COG0420	3'-5' exonuclease activity
BF28_3355	COG1024	Enoyl-CoA hydratase
BF28_3356	COG1280	lysine exporter protein (LysE YggA)
BF28_3358	COG2084	Dehydrogenase
BF28_3359	COG1960	acyl-CoA dehydrogenase activity
BF28_336	COG0183	Belongs to the thiolase family
BF28_3360	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF28_3361	COG2079	MmgE PrpD family protein
BF28_3362	COG0372	Belongs to the citrate synthase family
BF28_3363	COG4841	protein insertion into membrane
BF28_3364	COG2814	Major facilitator Superfamily
BF28_3365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_3365	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF28_337	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF28_3373	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_338	COG1960	acyl-CoA dehydrogenase activity
BF28_3388	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_3389	COG0671	phosphoesterase, PA-phosphatase related
BF28_339	COG1960	acyl-CoA dehydrogenase activity
BF28_3390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF28_3391	COG4326	sporulation control protein
BF28_3392	COG3064	Membrane
BF28_3392	COG4991	sh3 domain protein
BF28_3392	COG0515	serine threonine protein kinase
BF28_3399	COG1509	lysine 2,3-aminomutase activity
BF28_34	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF28_3400	COG3829	transcription factor binding
BF28_3401	COG0456	acetyltransferase
BF28_3402	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_3403	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF28_3404	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF28_3405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_3409	COG5506	Protein of unknown function (DUF1694)
BF28_3410	COG1012	belongs to the aldehyde dehydrogenase family
BF28_3411	COG1253	flavin adenine dinucleotide binding
BF28_3418	COG1174	glycine betaine transport
BF28_3419	COG0517	IMP dehydrogenase activity
BF28_3419	COG1125	glycine betaine transport
BF28_343	COG4821	SIS domain
BF28_3430	COG1064	alcohol dehydrogenase
BF28_3431	COG1737	Transcriptional regulator
BF28_3432	COG2197	response regulator
BF28_3433	COG2203	Gaf domain
BF28_3433	COG4585	Histidine kinase
BF28_3434	COG0668	transmembrane transport
BF28_3436	COG1051	belongs to the nudix hydrolase family
BF28_3437	COG1335	isochorismatase
BF28_3441	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_3442	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_3446	COG0367	asparagine synthase
BF28_3447	COG0071	Belongs to the small heat shock protein (HSP20) family
BF28_3448	COG1999	signal sequence binding
BF28_3449	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF28_3450	COG1307	EDD domain protein, DegV family
BF28_3452	COG0805	protein transport
BF28_3454	COG1272	protein, Hemolysin III
BF28_3455	COG0204	Acyl-transferase
BF28_3457	COG0768	penicillin binding
BF28_346	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF28_3461	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_3465	COG0546	phosphoglycolate phosphatase activity
BF28_3467	COG4473	ABC transporter
BF28_3468	COG1131	(ABC) transporter
BF28_347	COG1494	fructose-1,6-bisphosphatase
BF28_3470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF28_3471	COG0456	acetyltransferase
BF28_3473	COG1794	racemase activity, acting on amino acids and derivatives
BF28_3474	COG1454	alcohol dehydrogenase
BF28_3475	COG2610	gluconate transmembrane transporter activity
BF28_348	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF28_3480	COG0733	neurotransmitter:sodium symporter activity
BF28_3493	COG1674	ftsk spoiiie
BF28_3497	COG0017	Asparaginyl-tRNA synthetase
BF28_3498	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF28_3505	COG2136	Putative SAM-dependent methyltransferase
BF28_3505	COG2521	methyltransferase
BF28_3508	COG1413	lyase activity
BF28_351	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF28_3511	COG0629	single-stranded DNA binding
BF28_3514	COG0488	(ABC) transporter
BF28_3515	COG1418	mRNA catabolic process
BF28_352	COG2890	protein-(glutamine-N5) methyltransferase activity
BF28_3522	COG2359	stage V sporulation protein S
BF28_3529	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF28_3530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF28_3531	COG2146	nitrite reductase [NAD(P)H] activity
BF28_3532	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF28_3532	COG1587	Uroporphyrinogen-III synthase
BF28_3534	COG1648	precorrin-2 dehydrogenase activity
BF28_3537	COG2223	nitrite transmembrane transporter activity
BF28_3539	COG0314	molybdopterin synthase activity
BF28_3540	COG0303	'Molybdopterin
BF28_3541	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_3542	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF28_3543	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF28_3544	COG2181	nitrate reductase activity
BF28_3545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF28_3546	COG1140	nitrate reductase beta subunit
BF28_3547	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF28_355	COG0009	L-threonylcarbamoyladenylate synthase
BF28_3550	COG0714	Associated with various cellular activities
BF28_3551	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF28_3552	COG1305	Transglutaminase-like
BF28_3553	COG0386	Belongs to the glutathione peroxidase family
BF28_3555	COG0426	domain, Protein
BF28_3555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF28_3558	COG1595	DNA-templated transcription, initiation
BF28_3559	COG0604	alcohol dehydrogenase
BF28_3561	COG0346	lactoylglutathione lyase activity
BF28_3562	COG1082	Xylose isomerase domain protein TIM barrel
BF28_3566	COG2226	methyltransferase
BF28_3571	COG3874	Sporulation protein YtfJ
BF28_3584	COG0456	acetyltransferase
BF28_3590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_3591	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_3592	COG1819	glycosyl
BF28_3596	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF28_3598	COG0561	phosphatase activity
BF28_36	COG0024	Methionine aminopeptidase
BF28_360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF28_3602	COG2211	Major facilitator Superfamily
BF28_3603	COG0154	amidase activity
BF28_3605	COG1876	peptidase activity
BF28_3607	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_361	COG2259	Doxx family
BF28_3610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_3611	COG1114	Component of the transport system for branched-chain amino acids
BF28_3614	COG1253	flavin adenine dinucleotide binding
BF28_3615	COG2839	Protein conserved in bacteria
BF28_3616	COG0702	epimerase
BF28_3619	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_362	COG2190	(PTS) system
BF28_3620	COG1607	acyl-coa hydrolase
BF28_3621	COG3689	TIGRFAM TIGR03943 family protein
BF28_3622	COG0701	Predicted permease
BF28_3624	COG2244	polysaccharide biosynthetic process
BF28_3625	COG0586	Pfam SNARE associated Golgi protein
BF28_3626	COG1051	belongs to the nudix hydrolase family
BF28_3627	COG5337	Spore coat protein CotH
BF28_3629	COG0406	alpha-ribazole phosphatase activity
BF28_3632	COG4166	transmembrane transport
BF28_3634	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF28_3636	COG0702	epimerase
BF28_3638	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF28_3638	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF28_364	COG0698	ribose 5-phosphate isomerase
BF28_3648	COG0456	acetyltransferase
BF28_3649	COG0523	cobalamin synthesis protein
BF28_3650	COG4989	oxidoreductase activity
BF28_3652	COG1231	oxidoreductase activity
BF28_3654	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_3657	COG0783	Belongs to the Dps family
BF28_3658	COG3949	Membrane
BF28_3661	COG0840	transmembrane signaling receptor activity
BF28_3666	COG2814	Major facilitator Superfamily
BF28_3667	COG0667	Aldo Keto reductase
BF28_3668	COG0640	Transcriptional regulator
BF28_3669	COG1404	Belongs to the peptidase S8 family
BF28_3670	COG2002	toxin-antitoxin pair type II binding
BF28_3671	COG0577	efflux transmembrane transporter activity
BF28_3678	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF28_3680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_3681	COG1279	arginine transmembrane transporter activity
BF28_3682	COG2814	Major facilitator Superfamily
BF28_3684	COG1082	Xylose isomerase domain protein TIM barrel
BF28_3687	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_3688	COG4264	IucA IucC family
BF28_3690	COG1247	-acetyltransferase
BF28_3691	COG1285	pathogenesis
BF28_3693	COG0726	polysaccharide deacetylase
BF28_3694	COG5002	protein histidine kinase activity
BF28_3695	COG0745	RESPONSE REGULATOR receiver
BF28_3697	COG1316	TRANSCRIPTIONal
BF28_370	COG0356	it plays a direct role in the translocation of protons across the membrane
BF28_3702	COG0460	homoserine dehydrogenase
BF28_3706	COG0726	polysaccharide deacetylase
BF28_3709	COG0300	oxidoreductase activity
BF28_3710	COG5002	protein histidine kinase activity
BF28_3712	COG0745	RESPONSE REGULATOR receiver
BF28_3713	COG1132	(ABC) transporter
BF28_3715	COG0791	NLP P60 protein
BF28_3715	COG1388	LysM domain
BF28_3717	COG1686	Belongs to the peptidase S11 family
BF28_3718	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_3721	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF28_3722	COG4988	ABC transporter
BF28_3723	COG1294	oxidase, subunit
BF28_3724	COG1271	oxidase subunit
BF28_3730	COG0583	DNA-binding transcription factor activity
BF28_3732	COG0559	Belongs to the binding-protein-dependent transport system permease family
BF28_3734	COG0411	ABC transporter
BF28_3736	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_3737	COG2030	dehydratase
BF28_3738	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_3741	COG0523	cobalamin synthesis protein
BF28_3742	COG1231	oxidoreductase activity
BF28_3743	COG0039	L-malate dehydrogenase activity
BF28_3744	COG0628	permease
BF28_3747	COG0778	Nitroreductase
BF28_3748	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF28_3749	COG1959	2 iron, 2 sulfur cluster binding
BF28_3750	COG0583	DNA-binding transcription factor activity
BF28_3751	COG0697	spore germination
BF28_3753	COG4549	nuclear export factor GLE1
BF28_3754	COG1276	copper resistance
BF28_3754	COG2372	response to copper ion
BF28_3756	COG1114	Component of the transport system for branched-chain amino acids
BF28_3761	COG2002	toxin-antitoxin pair type II binding
BF28_3764	COG1131	(ABC) transporter
BF28_3767	COG1132	(ABC) transporter
BF28_3773	COG0006	proline dipeptidase activity
BF28_3779	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF28_3780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_3782	COG2390	Transcriptional regulator
BF28_3787	COG0531	amino acid
BF28_3789	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF28_3792	COG1914	H( )-stimulated, divalent metal cation uptake system
BF28_3797	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_38	COG0201	protein transport
BF28_380	COG5001	Diguanylate cyclase
BF28_380	COG3300	MHYT domain
BF28_3802	COG4166	transmembrane transport
BF28_3803	COG1073	alpha beta
BF28_3807	COG0427	acetyl-CoA hydrolase
BF28_3808	COG3279	Response regulator of the LytR AlgR family
BF28_381	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF28_3810	COG3384	dioxygenase
BF28_3811	COG2814	Major facilitator Superfamily
BF28_3816	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF28_3820	COG0028	Belongs to the TPP enzyme family
BF28_3821	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_3823	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_3826	COG2323	membrane
BF28_3827	COG5566	PFAM Mor transcription activator
BF28_3829	COG0733	neurotransmitter:sodium symporter activity
BF28_383	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF28_3830	COG2244	polysaccharide biosynthetic process
BF28_3833	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_3834	COG2223	nitrite transmembrane transporter activity
BF28_3835	COG4166	transmembrane transport
BF28_3836	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF28_3838	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_3839	COG0477	Major facilitator Superfamily
BF28_3841	COG1695	Transcriptional regulator
BF28_3843	COG1940	carbohydrate kinase activity
BF28_3844	COG1105	Belongs to the carbohydrate kinase PfkB family
BF28_3847	COG2222	sugar isomerase
BF28_3850	COG0395	ABC-type sugar transport system, permease component
BF28_3851	COG1175	transmembrane transport
BF28_3853	COG2508	Transcriptional regulator
BF28_3854	COG3842	ATPase activity
BF28_3859	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_3860	COG1051	belongs to the nudix hydrolase family
BF28_3866	COG3620	sequence-specific DNA binding
BF28_3869	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_387	COG0839	Belongs to the complex I subunit 6 family
BF28_3870	COG0784	Response regulator, receiver
BF28_3871	COG4191	Histidine kinase
BF28_3872	COG0281	malic enzyme
BF28_3873	COG1027	Aspartate ammonia-lyase
BF28_3875	COG0528	UMP kinase activity
BF28_3876	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_3879	COG1131	(ABC) transporter
BF28_3886	COG2733	membrane
BF28_389	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF28_3891	COG0785	Cytochrome C biogenesis protein
BF28_3895	COG3340	Belongs to the peptidase S51 family
BF28_3896	COG0534	Mate efflux family protein
BF28_3899	COG0114	fumarate hydratase activity
BF28_390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF28_3900	COG1757	Na H antiporter
BF28_3901	COG1216	Glycosyl transferase, family 2
BF28_3901	COG0438	transferase activity, transferring glycosyl groups
BF28_3902	COG0523	cobalamin synthesis protein
BF28_3903	COG0697	spore germination
BF28_3904	COG1802	Transcriptional regulator
BF28_391	COG1007	ATP synthesis coupled electron transport
BF28_3910	COG0367	asparagine synthase
BF28_3912	COG1846	Transcriptional regulator
BF28_3916	COG0406	alpha-ribazole phosphatase activity
BF28_3918	COG1686	Belongs to the peptidase S11 family
BF28_392	COG4836	Membrane
BF28_3923	COG1234	tRNA 3'-trailer cleavage
BF28_3924	COG1177	transmembrane transport
BF28_3925	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF28_3926	COG3842	ATPase activity
BF28_3932	COG2329	Antibiotic biosynthesis monooxygenase
BF28_3936	COG1309	transcriptional regulator
BF28_394	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF28_3942	COG4786	Flagellar basal body rod
BF28_3943	COG1419	protein localization to endoplasmic reticulum
BF28_3944	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF28_3945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF28_3947	COG1987	bacterial-type flagellum assembly
BF28_3948	COG1338	Plays a role in the flagellum-specific transport system
BF28_395	COG2385	sporulation resulting in formation of a cellular spore
BF28_3950	COG1776	CheC inhibitor of MCP methylation
BF28_3950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_3951	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_3953	COG0741	lytic transglycosylase activity
BF28_3954	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_3954	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_3955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_3957	COG0784	Response regulator, receiver
BF28_3957	COG0835	chemotaxis
BF28_396	COG3279	Response regulator of the LytR AlgR family
BF28_3964	COG1157	protein secretion by the type III secretion system
BF28_3966	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_3967	COG1766	The M ring may be actively involved in energy transduction
BF28_3968	COG1677	Flagellar hook-basal body complex protein FliE
BF28_3969	COG1558	bacterial-type flagellum-dependent cell motility
BF28_3970	COG1815	bacterial-type flagellum-dependent cell motility
BF28_3974	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_3975	COG1256	bacterial-type flagellum assembly
BF28_3979	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF28_3982	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_3982	COG1776	CheC inhibitor of MCP methylation
BF28_3983	COG0643	Histidine kinase
BF28_3983	COG2198	Histidine kinase
BF28_3984	COG2201	protein-glutamate methylesterase activity
BF28_3985	COG1360	Flagellar Motor Protein
BF28_3986	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF28_3988	COG1923	regulation of RNA biosynthetic process
BF28_399	COG0739	heme binding
BF28_4001	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF28_4002	COG2323	membrane
BF28_4004	COG4978	Transcriptional regulator
BF28_4004	COG0789	Transcriptional regulator
BF28_4005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_4006	COG0475	glutathione-regulated potassium exporter activity
BF28_4008	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_4009	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_4010	COG3162	membrane
BF28_4013	COG1280	lysine exporter protein (LysE YggA)
BF28_4014	COG3403	YqcI/YcgG family
BF28_4021	COG0328	RNA-DNA hybrid ribonuclease activity
BF28_4025	COG0454	-acetyltransferase
BF28_4028	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_403	COG0110	maltose O-acetyltransferase activity
BF28_4031	COG0754	glutathionylspermidine amidase activity
BF28_4036	COG0456	acetyltransferase
BF28_4038	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_4040	COG2311	Membrane
BF28_4041	COG2233	PERMEase
BF28_4043	COG0024	Methionine aminopeptidase
BF28_4044	COG3173	Aminoglycoside phosphotransferase
BF28_4046	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF28_4047	COG1199	ATP-dependent helicase activity
BF28_4049	COG0116	Belongs to the methyltransferase superfamily
BF28_405	COG0726	polysaccharide deacetylase
BF28_406	COG1609	Transcriptional regulator
BF28_4060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_4060	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF28_4062	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF28_4063	COG3935	DnaD domain protein
BF28_4067	COG1199	ATP-dependent helicase activity
BF28_4067	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF28_4074	COG0438	transferase activity, transferring glycosyl groups
BF28_4075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF28_4078	COG1694	Mazg nucleotide pyrophosphohydrolase
BF28_4079	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_4081	COG2738	Putative neutral zinc metallopeptidase
BF28_4084	COG4347	Protein of unknown function (DUF1405)
BF28_4086	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF28_4090	COG0457	Tetratricopeptide repeat
BF28_4094	COG0105	UTP biosynthetic process
BF28_4095	COG0142	geranyltranstransferase activity
BF28_4097	COG0142	geranyltranstransferase activity
BF28_4100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_4114	COG0252	asparaginase activity
BF28_4115	COG0492	ferredoxin-NADP+ reductase activity
BF28_4119	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF28_4120	COG4862	establishment of competence for transformation
BF28_4122	COG1408	metallophosphoesterase
BF28_4124	COG1266	CAAX protease self-immunity
BF28_4125	COG0514	ATP-dependent DNA helicase (RecQ)
BF28_4127	COG1141	Ferredoxin
BF28_4128	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF28_4130	COG4942	peptidase
BF28_4131	COG2096	Adenosyltransferase
BF28_4132	COG5002	protein histidine kinase activity
BF28_4133	COG0745	RESPONSE REGULATOR receiver
BF28_4134	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF28_4135	COG1333	cytochrome c biogenesis protein
BF28_4137	COG1187	pseudouridine synthase activity
BF28_4138	COG0700	Nucleoside recognition
BF28_4139	COG2715	membrane protein required for spore maturation
BF28_4140	COG1686	Belongs to the peptidase S11 family
BF28_4141	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_4144	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF28_4144	COG0392	lysyltransferase activity
BF28_4148	COG5002	protein histidine kinase activity
BF28_4149	COG0582	viral genome integration into host DNA
BF28_415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF28_4151	COG1801	Protein of unknown function DUF72
BF28_4152	COG3852	Histidine kinase
BF28_4155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_4156	COG1392	Phosphate transport regulator
BF28_4157	COG0306	phosphate transporter
BF28_4158	COG0730	response to heat
BF28_416	COG1682	transport, permease protein
BF28_4166	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF28_4168	COG1114	Component of the transport system for branched-chain amino acids
BF28_4170	COG2197	response regulator
BF28_4171	COG4585	Histidine kinase
BF28_4172	COG4758	membrane
BF28_4175	COG1757	Na H antiporter
BF28_4179	COG0733	neurotransmitter:sodium symporter activity
BF28_418	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF28_4180	COG1648	precorrin-2 dehydrogenase activity
BF28_4184	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF28_4185	COG0529	Catalyzes the synthesis of activated sulfate
BF28_4189	COG0019	diaminopimelate decarboxylase activity
BF28_4191	COG1368	sulfuric ester hydrolase activity
BF28_4192	COG1183	phosphatidylcholine synthase activity
BF28_4195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF28_4210	COG0440	acetolactate synthase activity
BF28_4211	COG0028	Belongs to the TPP enzyme family
BF28_4212	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_4216	COG3874	Sporulation protein YtfJ
BF28_4217	COG4709	membrane
BF28_4218	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_4219	COG1301	dicarboxylic acid transport
BF28_422	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF28_4221	COG1846	Transcriptional regulator
BF28_4224	COG1968	undecaprenyl-diphosphatase activity
BF28_4229	COG3173	Aminoglycoside phosphotransferase
BF28_423	COG0745	RESPONSE REGULATOR receiver
BF28_4232	COG0716	FMN binding
BF28_4237	COG1696	Membrane protein involved in D-alanine export
BF28_4239	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF28_424	COG5002	protein histidine kinase activity
BF28_4240	COG2070	2-Nitropropane dioxygenase
BF28_4241	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_4243	COG1335	isochorismatase
BF28_4245	COG1522	sequence-specific DNA binding
BF28_4247	COG1266	CAAX protease self-immunity
BF28_4248	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_4249	COG1131	(ABC) transporter
BF28_4251	COG1131	(ABC) transporter
BF28_4252	COG1725	Transcriptional regulator
BF28_4253	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_4254	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_4255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_4256	COG1780	Probably involved in ribonucleotide reductase function
BF28_4262	COG4873	Protein conserved in bacteria
BF28_4265	COG0720	synthase
BF28_4267	COG5002	protein histidine kinase activity
BF28_4269	COG2318	DinB family
BF28_4271	COG1846	Transcriptional regulator
BF28_4272	COG3852	Histidine kinase
BF28_4274	COG2861	carbohydrate metabolic process
BF28_4276	COG0235	Class ii aldolase
BF28_4279	COG1349	DNA-binding transcription factor activity
BF28_4284	COG3842	ATPase activity
BF28_4285	COG1840	ABC-type Fe3 transport system, periplasmic component
BF28_4288	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_4290	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF28_4291	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_4295	COG2030	dehydratase
BF28_4297	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_4298	COG0861	Integral membrane protein TerC family
BF28_4299	COG2116	formate transmembrane transporter activity
BF28_43	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF28_4301	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF28_4305	COG2186	Transcriptional regulator
BF28_4306	COG5002	protein histidine kinase activity
BF28_4307	COG0745	RESPONSE REGULATOR receiver
BF28_4309	COG3835	regulator
BF28_431	COG1136	(ABC) transporter
BF28_4310	COG0277	FAD linked oxidase domain protein
BF28_4311	COG0247	lactate metabolic process
BF28_4312	COG2340	Cysteine-rich secretory protein family
BF28_4314	COG0564	pseudouridine synthase activity
BF28_4316	COG2409	Drug exporters of the RND superfamily
BF28_4318	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF28_4319	COG1177	transmembrane transport
BF28_432	COG0577	efflux transmembrane transporter activity
BF28_4320	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF28_4322	COG1012	belongs to the aldehyde dehydrogenase family
BF28_4328	COG0681	Belongs to the peptidase S26 family
BF28_4329	COG1686	Belongs to the peptidase S11 family
BF28_4331	COG2226	methyltransferase
BF28_4349	COG1476	TRANSCRIPTIONal
BF28_435	COG1191	sigma factor activity
BF28_4351	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_4355	COG2226	methyltransferase
BF28_4362	COG5634	Uncharacterized conserved protein (DUF2278)
BF28_4363	COG1620	l-lactate permease
BF28_4370	COG0512	Glutamine amidotransferase of anthranilate synthase
BF28_4370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF28_4372	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_4373	COG5492	domain, Protein
BF28_4376	COG2382	esterase
BF28_4378	COG2153	protein acetylation
BF28_4386	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF28_4389	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF28_4393	COG0457	Tetratricopeptide repeat
BF28_4393	COG0463	Glycosyl transferase, family 2
BF28_4397	COG0463	Glycosyl transferase, family 2
BF28_4397	COG1216	Glycosyl transferase, family 2
BF28_4398	COG0772	Belongs to the SEDS family
BF28_4401	COG0564	pseudouridine synthase activity
BF28_4402	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF28_4403	COG2357	RelA SpoT domain protein
BF28_4405	COG4116	CYTH
BF28_4406	COG2346	COG2346, Truncated hemoglobins
BF28_4409	COG1164	Oligoendopeptidase f
BF28_441	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_4411	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_4412	COG4862	establishment of competence for transformation
BF28_4413	COG0861	Integral membrane protein TerC family
BF28_4414	COG1393	Belongs to the ArsC family
BF28_4416	COG4166	transmembrane transport
BF28_4417	COG0534	Mate efflux family protein
BF28_4418	COG4608	Belongs to the ABC transporter superfamily
BF28_4419	COG0444	Belongs to the ABC transporter superfamily
BF28_442	COG4715	Zinc finger, swim domain protein
BF28_4420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_4421	COG0601	transmembrane transport
BF28_4422	COG4166	transmembrane transport
BF28_4424	COG0180	Tryptophanyl-tRNA synthetase
BF28_4426	COG5504	Zn-dependent protease
BF28_4427	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF28_4428	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_4431	COG2267	carboxylic ester hydrolase activity
BF28_4433	COG0542	response to heat
BF28_4435	COG0561	phosphatase activity
BF28_4438	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_4440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_4441	COG2996	Protein conserved in bacteria
BF28_4445	COG0004	ammonium transporteR
BF28_4446	COG0753	catalase activity
BF28_4448	COG0367	asparagine synthase
BF28_4453	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF28_4465	COG0398	Pfam SNARE associated Golgi protein
BF28_4466	COG4903	ComK protein
BF28_4469	COG1278	Cold shock
BF28_447	COG3584	3D domain protein
BF28_447	COG1388	LysM domain
BF28_4471	COG2224	Isocitrate lyase
BF28_4472	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF28_4473	COG0497	DNA recombination
BF28_4476	COG0697	spore germination
BF28_4477	COG0840	transmembrane signaling receptor activity
BF28_4478	COG0501	Belongs to the peptidase M48B family
BF28_448	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_4483	COG0745	RESPONSE REGULATOR receiver
BF28_4484	COG2205	protein histidine kinase activity
BF28_4486	COG2207	Transcriptional regulator
BF28_4486	COG3708	Transcriptional regulator
BF28_4487	COG1595	DNA-templated transcription, initiation
BF28_4489	COG1078	dGTPase activity
BF28_4490	COG1408	metallophosphoesterase
BF28_4494	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_4496	COG0095	Lipoate-protein ligase
BF28_4497	COG1234	tRNA 3'-trailer cleavage
BF28_4499	COG1609	Transcriptional regulator
BF28_450	COG1215	transferase activity, transferring glycosyl groups
BF28_4500	COG2378	regulation of single-species biofilm formation
BF28_4502	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_4505	COG1511	domain protein
BF28_4506	COG1309	transcriptional regulator
BF28_4516	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_4517	COG2329	Antibiotic biosynthesis monooxygenase
BF28_4518	COG3428	Bacterial PH domain
BF28_4519	COG3402	PFAM membrane-flanked domain
BF28_452	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_4527	COG3428	Bacterial PH domain
BF28_4528	COG3402	PFAM membrane-flanked domain
BF28_453	COG0791	NLP P60 protein
BF28_453	COG1388	LysM domain
BF28_4530	COG1309	transcriptional regulator
BF28_4545	COG4473	ABC transporter
BF28_4546	COG1131	(ABC) transporter
BF28_4547	COG0537	adenosine 5'-monophosphoramidase activity
BF28_4548	COG4980	gas vesicle protein
BF28_455	COG1368	sulfuric ester hydrolase activity
BF28_4552	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_4553	COG3973	AAA domain
BF28_4555	COG0477	Major facilitator Superfamily
BF28_4556	COG0477	Major facilitator Superfamily
BF28_4564	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF28_4566	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF28_4567	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF28_457	COG2389	metal-binding protein
BF28_4572	COG2267	carboxylic ester hydrolase activity
BF28_4574	COG0457	Tetratricopeptide repeat
BF28_4575	COG0346	lactoylglutathione lyase activity
BF28_4576	COG0346	lactoylglutathione lyase activity
BF28_4583	COG4717	serine-type aminopeptidase activity
BF28_4584	COG0420	3'-5' exonuclease activity
BF28_459	COG1620	l-lactate permease
BF28_4594	COG2205	protein histidine kinase activity
BF28_4595	COG0745	RESPONSE REGULATOR receiver
BF28_4597	COG0393	Putative heavy-metal-binding
BF28_4602	COG5002	protein histidine kinase activity
BF28_4602	COG0784	Response regulator, receiver
BF28_4602	COG2205	protein histidine kinase activity
BF28_4603	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF28_4604	COG2208	phosphoserine phosphatase activity
BF28_4606	COG1191	sigma factor activity
BF28_4611	COG3237	CsbD-like
BF28_4622	COG3437	response regulator, receiver
BF28_4622	COG2770	Histidine kinase
BF28_4629	COG1959	2 iron, 2 sulfur cluster binding
BF28_463	COG1620	l-lactate permease
BF28_4631	COG2376	Dihydroxyacetone kinase
BF28_4633	COG2376	Dihydroxyacetone kinase
BF28_4639	COG1183	phosphatidylcholine synthase activity
BF28_4641	COG2723	6-phospho-beta-galactosidase activity
BF28_4642	COG2190	(PTS) system
BF28_4642	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_4642	COG1263	PTS System
BF28_4643	COG3711	transcriptional antiterminator
BF28_4646	COG3320	Male sterility
BF28_4646	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF28_465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_466	COG1294	oxidase, subunit
BF28_4662	COG0305	Participates in initiation and elongation during chromosome replication
BF28_4665	COG4978	Transcriptional regulator
BF28_4665	COG0789	Transcriptional regulator
BF28_467	COG1271	oxidase subunit
BF28_4672	COG1104	cysteine desulfurase activity
BF28_4674	COG0419	ATPase involved in DNA repair
BF28_4676	COG0433	COG0433 Predicted ATPase
BF28_4686	COG0556	nucleotide-excision repair
BF28_469	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF28_4690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF28_4692	COG4608	Belongs to the ABC transporter superfamily
BF28_4693	COG0444	Belongs to the ABC transporter superfamily
BF28_4694	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_4695	COG0601	transmembrane transport
BF28_470	COG0583	DNA-binding transcription factor activity
BF28_4701	COG3938	Belongs to the proline racemase family
BF28_4705	COG1363	Peptidase, m42
BF28_4709	COG1024	Enoyl-CoA hydratase
BF28_471	COG1511	domain protein
BF28_4713	COG1696	Membrane protein involved in D-alanine export
BF28_4716	COG4196	transglutaminase domain protein
BF28_4717	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_4719	COG2244	polysaccharide biosynthetic process
BF28_472	COG0346	lactoylglutathione lyase activity
BF28_4724	COG0659	secondary active sulfate transmembrane transporter activity
BF28_4726	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_4727	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF28_4728	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF28_4728	COG3409	Peptidoglycan-binding domain 1 protein
BF28_4730	COG0561	phosphatase activity
BF28_4732	COG3527	Alpha-acetolactate decarboxylase
BF28_4733	COG0028	Belongs to the TPP enzyme family
BF28_474	COG1301	dicarboxylic acid transport
BF28_4741	COG2197	response regulator
BF28_4742	COG4585	Histidine kinase
BF28_4747	COG0189	ligase activity
BF28_475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_4750	COG1126	abc transporter atp-binding protein
BF28_4751	COG0765	amino acid transport
BF28_4752	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_4753	COG1132	(ABC) transporter
BF28_4754	COG1132	(ABC) transporter
BF28_4755	COG1012	belongs to the aldehyde dehydrogenase family
BF28_4756	COG0531	amino acid
BF28_4758	COG0693	protein deglycase activity
BF28_4758	COG0753	catalase activity
BF28_4759	COG0693	protein deglycase activity
BF28_4761	COG2211	Major facilitator Superfamily
BF28_4762	COG4533	DNA binding
BF28_4763	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_4765	COG1733	regulation of RNA biosynthetic process
BF28_4766	COG1063	alcohol dehydrogenase
BF28_4768	COG2124	cytochrome p450
BF28_4769	COG1309	transcriptional regulator
BF28_477	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_4771	COG0477	Major facilitator Superfamily
BF28_4772	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_4773	COG1846	Transcriptional regulator
BF28_4774	COG1733	regulation of RNA biosynthetic process
BF28_4775	COG2814	Major facilitator Superfamily
BF28_4776	COG1309	transcriptional regulator
BF28_4777	COG2076	Multidrug Resistance protein
BF28_4778	COG2076	Multidrug Resistance protein
BF28_4780	COG1522	sequence-specific DNA binding
BF28_4784	COG2259	Doxx family
BF28_4787	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_4787	COG1263	PTS System
BF28_4788	COG1263	PTS System
BF28_4788	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_479	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF28_4790	COG1737	Transcriptional regulator
BF28_4792	COG0475	glutathione-regulated potassium exporter activity
BF28_4793	COG0531	amino acid
BF28_4800	COG0586	Pfam SNARE associated Golgi protein
BF28_4807	COG3546	catalase activity
BF28_4808	COG1114	Component of the transport system for branched-chain amino acids
BF28_4809	COG0577	efflux transmembrane transporter activity
BF28_481	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_4812	COG5522	Integral membrane protein (intg_mem_TP0381)
BF28_4814	COG1136	(ABC) transporter
BF28_4815	COG0577	efflux transmembrane transporter activity
BF28_4816	COG1388	LysM domain
BF28_4816	COG3584	3D domain protein
BF28_482	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_4820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_4821	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_4822	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_4822	COG3711	transcriptional antiterminator
BF28_4825	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF28_4826	COG0604	alcohol dehydrogenase
BF28_4827	COG1316	TRANSCRIPTIONal
BF28_4829	COG0730	response to heat
BF28_483	COG1486	melibiose metabolic process
BF28_4830	COG2210	Belongs to the sulfur carrier protein TusA family
BF28_4832	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_4833	COG0425	Belongs to the sulfur carrier protein TusA family
BF28_4834	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_4834	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_4835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_4835	COG0425	Belongs to the sulfur carrier protein TusA family
BF28_4836	COG1937	Protein conserved in bacteria
BF28_4837	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF28_4839	COG2719	SpoVR family
BF28_484	COG3394	polysaccharide catabolic process
BF28_4840	COG0778	Nitroreductase
BF28_4848	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_4852	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_4853	COG2252	PERMEase
BF28_4856	COG1846	Transcriptional regulator
BF28_4857	COG2814	Major facilitator Superfamily
BF28_4858	COG2205	protein histidine kinase activity
BF28_4865	COG0351	phosphomethylpyrimidine kinase
BF28_4866	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_4868	COG2104	thiamine diphosphate biosynthetic process
BF28_4869	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_487	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF28_487	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF28_4870	COG0352	thiamine-phosphate diphosphorylase activity
BF28_4871	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_4872	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_4873	COG1116	anion transmembrane transporter activity
BF28_4874	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF28_4878	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF28_489	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF28_490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF28_4903	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF28_4905	COG0581	inorganic phosphate transmembrane transporter activity
BF28_4906	COG0573	inorganic phosphate transmembrane transporter activity
BF28_4907	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF28_4908	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_4908	COG1918	ferrous iron import across plasma membrane
BF28_4909	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_491	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF28_4910	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_4912	COG0531	amino acid
BF28_4913	COG0697	spore germination
BF28_4914	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_4917	COG4990	cell redox homeostasis
BF28_4918	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF28_4919	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF28_492	COG1316	TRANSCRIPTIONal
BF28_4922	COG0475	glutathione-regulated potassium exporter activity
BF28_4922	COG0569	domain protein
BF28_4924	COG2153	protein acetylation
BF28_4927	COG2252	PERMEase
BF28_4928	COG1113	amino acid transport
BF28_493	COG1739	Uncharacterized protein family UPF0029
BF28_4931	COG1114	Component of the transport system for branched-chain amino acids
BF28_4932	COG3104	oligopeptide transport
BF28_4935	COG1476	TRANSCRIPTIONal
BF28_4936	COG1388	LysM domain
BF28_4936	COG3584	3D domain protein
BF28_4937	COG0840	transmembrane signaling receptor activity
BF28_494	COG1307	EDD domain protein, DegV family
BF28_4943	COG3568	Endonuclease Exonuclease Phosphatase
BF28_4948	COG1063	alcohol dehydrogenase
BF28_495	COG1733	regulation of RNA biosynthetic process
BF28_4952	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF28_4953	COG1879	ABC-type sugar transport system periplasmic component
BF28_4954	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF28_4957	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF28_4958	COG1609	Transcriptional regulator
BF28_4959	COG0477	Major facilitator Superfamily
BF28_496	COG0791	NLP P60 protein
BF28_496	COG1388	LysM domain
BF28_4960	COG1846	Transcriptional regulator
BF28_4961	COG2271	Major facilitator Superfamily
BF28_4963	COG4608	Belongs to the ABC transporter superfamily
BF28_4964	COG0601	transmembrane transport
BF28_4966	COG0747	negative chemotaxis
BF28_4969	COG0659	secondary active sulfate transmembrane transporter activity
BF28_497	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF28_4972	COG5002	protein histidine kinase activity
BF28_4973	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF28_4974	COG2378	regulation of single-species biofilm formation
BF28_4979	COG0833	amino acid
BF28_498	COG1040	competence protein
BF28_4980	COG0765	amino acid transport
BF28_4981	COG0765	amino acid transport
BF28_4982	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_4983	COG1126	abc transporter atp-binding protein
BF28_4984	COG1115	amino acid carrier protein
BF28_4985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_4987	COG0697	spore germination
BF28_499	COG1278	Cold shock
BF28_4990	COG0366	Alpha amylase catalytic
BF28_4991	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_4991	COG1263	PTS System
BF28_4992	COG2188	Transcriptional regulator
BF28_4993	COG0531	amino acid
BF28_4997	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_4998	COG0714	Associated with various cellular activities
BF28_4999	COG4548	von Willebrand factor, type A
BF28_500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF28_5001	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BF28_5002	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_5003	COG0156	8-amino-7-oxononanoate synthase activity
BF28_5004	COG2226	methyltransferase
BF28_5006	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_5007	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_5008	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_5009	COG3104	oligopeptide transport
BF28_5012	COG1620	l-lactate permease
BF28_5013	COG1027	Aspartate ammonia-lyase
BF28_5014	COG1253	flavin adenine dinucleotide binding
BF28_5015	COG0346	lactoylglutathione lyase activity
BF28_5016	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_5017	COG1316	TRANSCRIPTIONal
BF28_5018	COG2720	vancomycin resistance protein
BF28_502	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF28_5022	COG3227	Zinc metalloprotease (Elastase)
BF28_5025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF28_5026	COG2217	Heavy metal translocating P-type atpase
BF28_5027	COG0640	Transcriptional regulator
BF28_5028	COG0531	amino acid
BF28_5031	COG2427	Protein of unknown function (DUF1641)
BF28_5032	COG3383	formate dehydrogenase (NAD+) activity
BF28_5033	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF28_5034	COG0454	-acetyltransferase
BF28_5034	COG0456	acetyltransferase
BF28_5036	COG0745	RESPONSE REGULATOR receiver
BF28_5037	COG5002	protein histidine kinase activity
BF28_5039	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_504	COG2884	Cell division ATP-binding protein ftsE
BF28_5040	COG0697	spore germination
BF28_5042	COG0281	malic enzyme
BF28_5043	COG3493	citrate carrier protein
BF28_5044	COG4565	transcriptional regulatory protein
BF28_5045	COG3290	protein histidine kinase activity
BF28_5047	COG4990	cell redox homeostasis
BF28_5049	COG5002	protein histidine kinase activity
BF28_505	COG2177	Part of the ABC transporter FtsEX involved in
BF28_5050	COG0745	RESPONSE REGULATOR receiver
BF28_5051	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF28_5053	COG0395	ABC-type sugar transport system, permease component
BF28_5054	COG1175	transmembrane transport
BF28_5055	COG3842	ATPase activity
BF28_5056	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF28_506	COG3409	Peptidoglycan-binding domain 1 protein
BF28_506	COG0793	Belongs to the peptidase S41A family
BF28_5061	COG2851	Citrate transporter
BF28_5063	COG4565	transcriptional regulatory protein
BF28_5064	COG3290	protein histidine kinase activity
BF28_5066	COG2268	Band 7 protein
BF28_5067	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF28_5069	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_507	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_5070	COG0765	amino acid transport
BF28_5071	COG0765	amino acid transport
BF28_5072	COG1126	abc transporter atp-binding protein
BF28_5073	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_5078	COG2766	serine protein kinase
BF28_508	COG1132	(ABC) transporter
BF28_5081	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF28_5083	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF28_5085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF28_5086	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF28_511	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF28_5110	COG0735	belongs to the Fur family
BF28_5111	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF28_5115	COG4555	ABC transporter
BF28_5117	COG0070	glutamate synthase
BF28_5117	COG0069	glutamate synthase activity
BF28_5117	COG0067	glutamate synthase
BF28_5118	COG4129	membrane
BF28_5119	COG1132	(ABC) transporter
BF28_5124	COG1194	a g-specific adenine glycosylase
BF28_5125	COG1988	membrane-bound metal-dependent
BF28_513	COG0583	DNA-binding transcription factor activity
BF28_5131	COG1090	epimerase
BF28_5136	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF28_5139	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF28_5139	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_514	COG2855	membrane
BF28_5141	COG0463	Glycosyl transferase, family 2
BF28_5145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_5146	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_5146	COG1263	PTS System
BF28_5147	COG2066	Belongs to the glutaminase family
BF28_5152	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_5153	COG0833	amino acid
BF28_5155	COG3829	transcription factor binding
BF28_5158	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF28_5159	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF28_5163	COG0535	radical SAM domain protein
BF28_5165	COG0387	Pfam Sodium calcium exchanger
BF28_5166	COG3871	stress protein (general stress protein 26)
BF28_5169	COG0586	Pfam SNARE associated Golgi protein
BF28_5171	COG0681	Belongs to the peptidase S26 family
BF28_5173	COG0697	spore germination
BF28_5174	COG2217	Heavy metal translocating P-type atpase
BF28_5175	COG1295	ribonuclease BN
BF28_5177	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF28_5180	COG3853	Toxic anion resistance protein (TelA)
BF28_5182	COG0861	Integral membrane protein TerC family
BF28_5183	COG2310	stress, protein
BF28_5184	COG2310	stress, protein
BF28_5185	COG2310	stress, protein
BF28_5191	COG2270	Major facilitator Superfamily
BF28_520	COG0789	Transcriptional regulator
BF28_5200	COG0488	(ABC) transporter
BF28_5202	COG1116	anion transmembrane transporter activity
BF28_5204	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_5207	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF28_5214	COG2190	(PTS) system
BF28_5214	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_5214	COG1263	PTS System
BF28_5215	COG0366	Alpha amylase catalytic
BF28_5216	COG0840	transmembrane signaling receptor activity
BF28_5217	COG0840	transmembrane signaling receptor activity
BF28_5219	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_5220	COG0765	amino acid transport
BF28_5222	COG0723	plastoquinol--plastocyanin reductase activity
BF28_5222	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_5223	COG2814	Major facilitator Superfamily
BF28_5224	COG3541	Predicted nucleotidyltransferase
BF28_5229	COG5002	protein histidine kinase activity
BF28_523	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF28_5235	COG0166	Belongs to the GPI family
BF28_5238	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_5239	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_5240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_5241	COG0235	Class ii aldolase
BF28_5243	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF28_5244	COG0450	alkyl hydroperoxide reductase
BF28_5247	COG1473	amidohydrolase
BF28_525	COG1950	PFAM Membrane protein of
BF28_5253	COG4807	Protein conserved in bacteria
BF28_5254	COG5002	protein histidine kinase activity
BF28_5255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF28_5256	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF28_5257	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_5260	COG2309	aminopeptidase activity
BF28_5261	COG2076	Multidrug Resistance protein
BF28_5262	COG1012	belongs to the aldehyde dehydrogenase family
BF28_5264	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF28_5265	COG0546	phosphoglycolate phosphatase activity
BF28_5266	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF28_5267	COG1597	lipid kinase activity
BF28_5271	COG4682	membrane
BF28_5272	COG1846	Transcriptional regulator
BF28_5273	COG0003	Pfam Anion-transporting ATPase
BF28_5277	COG2011	ABC-type metal ion transport system permease component
BF28_5279	COG1335	isochorismatase
BF28_5283	COG4851	CamS sex pheromone cAM373 precursor
BF28_5285	COG0210	DNA helicase
BF28_529	COG0110	maltose O-acetyltransferase activity
BF28_5290	COG0151	Belongs to the GarS family
BF28_5292	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF28_5294	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF28_5297	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF28_5299	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF28_530	COG0457	Tetratricopeptide repeat
BF28_5300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF28_5301	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF28_5302	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF28_5308	COG0697	spore germination
BF28_531	COG0492	ferredoxin-NADP+ reductase activity
BF28_5312	COG0745	RESPONSE REGULATOR receiver
BF28_5313	COG2205	protein histidine kinase activity
BF28_5326	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF28_533	COG1051	belongs to the nudix hydrolase family
BF28_5332	COG5002	protein histidine kinase activity
BF28_5334	COG2252	PERMEase
BF28_5337	COG5444	nuclease activity
BF28_5340	COG1266	CAAX protease self-immunity
BF28_5343	COG0488	(ABC) transporter
BF28_5344	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF28_5345	COG0456	acetyltransferase
BF28_5346	COG1214	PFAM Peptidase M22, glycoprotease
BF28_5347	COG0802	atpase or kinase
BF28_535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF28_5366	COG2183	response to ionizing radiation
BF28_5367	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF28_5368	COG0864	Transcriptional regulator
BF28_5369	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF28_537	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_5370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF28_5372	COG4294	response to UV
BF28_5373	COG0705	Rhomboid family
BF28_5373	COG0457	Tetratricopeptide repeat
BF28_5375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF28_5379	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF28_5380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF28_5386	COG0561	phosphatase activity
BF28_5387	COG4608	Belongs to the ABC transporter superfamily
BF28_5388	COG0444	Belongs to the ABC transporter superfamily
BF28_539	COG2323	membrane
BF28_5390	COG0601	transmembrane transport
BF28_5391	COG0747	negative chemotaxis
BF28_5395	COG0488	(ABC) transporter
BF28_5399	COG5298	Protein conserved in bacteria
BF28_5401	COG0084	hydrolase, TatD family'
BF28_5404	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_5406	COG1609	Transcriptional regulator
BF28_5408	COG0204	Acyl-transferase
BF28_5411	COG0697	spore germination
BF28_5415	COG1910	domain protein
BF28_5416	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF28_5417	COG4149	molybdate abc transporter
BF28_542	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_5421	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_5422	COG0656	L-ascorbic acid biosynthetic process
BF28_5423	COG4166	transmembrane transport
BF28_5424	COG4166	transmembrane transport
BF28_5426	COG1309	transcriptional regulator
BF28_5428	COG2207	Transcriptional regulator
BF28_5430	COG4166	transmembrane transport
BF28_5431	COG4608	Belongs to the ABC transporter superfamily
BF28_5432	COG0444	Belongs to the ABC transporter superfamily
BF28_5433	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_5434	COG0601	transmembrane transport
BF28_5437	COG2814	Major facilitator Superfamily
BF28_5439	COG2271	Major facilitator Superfamily
BF28_5440	COG0277	FAD linked oxidase domain protein
BF28_5443	COG1464	Belongs to the NlpA lipoprotein family
BF28_5445	COG2011	ABC-type metal ion transport system permease component
BF28_5446	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_5452	COG0823	Involved in the tonB-independent uptake of proteins
BF28_5452	COG4946	Tricorn protease homolog
BF28_5452	COG1506	peptidase
BF28_5453	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF28_5457	COG0596	Alpha beta hydrolase
BF28_5461	COG0675	Transposase, IS605 OrfB family
BF28_5463	COG2304	oxidoreductase activity
BF28_5466	COG0551	DNA topoisomerase type I activity
BF28_5466	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF28_5471	COG0436	Aminotransferase
BF28_5474	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF28_548	COG0457	Tetratricopeptide repeat
BF28_5480	COG2801	Transposase and inactivated derivatives
BF28_5481	COG3718	enzyme involved in inositol metabolism
BF28_5483	COG1609	Transcriptional regulator
BF28_5488	COG0673	inositol 2-dehydrogenase activity
BF28_5489	COG2814	Major facilitator Superfamily
BF28_5490	COG1609	Transcriptional regulator
BF28_5491	COG1609	Transcriptional regulator
BF28_5492	COG2814	Major facilitator Superfamily
BF28_5493	COG0673	inositol 2-dehydrogenase activity
BF28_5505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_5510	COG3397	chitin binding
BF28_5519	COG3238	Protein conserved in bacteria
BF28_552	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF28_5520	COG0167	dihydroorotate dehydrogenase activity
BF28_5521	COG0167	dihydroorotate dehydrogenase activity
BF28_5525	COG0546	phosphoglycolate phosphatase activity
BF28_5526	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_5527	COG0697	spore germination
BF28_5542	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF28_5542	COG0456	acetyltransferase
BF28_555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF28_5555	COG0741	lytic transglycosylase activity
BF28_5555	COG0791	NLP P60 protein
BF28_5576	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF28_5582	COG0681	Belongs to the peptidase S26 family
BF28_5592	COG3344	reverse transcriptase
BF28_5594	COG2801	Transposase and inactivated derivatives
BF28_5596	COG1780	Probably involved in ribonucleotide reductase function
BF28_5617	COG0586	Pfam SNARE associated Golgi protein
BF28_5619	COG0745	RESPONSE REGULATOR receiver
BF28_562	COG1346	cytolysis
BF28_5621	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF28_5627	COG0582	viral genome integration into host DNA
BF28_563	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF28_5638	COG1733	regulation of RNA biosynthetic process
BF28_5639	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF28_564	COG1647	Serine aminopeptidase, S33
BF28_5640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_5640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_5644	COG3773	Cell wall hydrolase
BF28_565	COG0557	exoribonuclease II activity
BF28_5651	COG0697	spore germination
BF28_5654	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BF28_5655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BF28_5663	COG2323	membrane
BF28_5664	COG4990	cell redox homeostasis
BF28_5690	COG3331	DNA recombination
BF28_5699	COG1073	alpha beta
BF28_5702	COG3104	oligopeptide transport
BF28_5705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_5714	COG0726	polysaccharide deacetylase
BF28_5721	COG1309	transcriptional regulator
BF28_5729	COG2814	Major facilitator Superfamily
BF28_5731	COG1136	(ABC) transporter
BF28_5731	COG0577	efflux transmembrane transporter activity
BF28_5744	COG2801	Transposase and inactivated derivatives
BF28_5749	COG2801	Transposase and inactivated derivatives
BF28_5750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_5759	COG4974	Belongs to the 'phage' integrase family
BF28_576	COG3223	Belongs to the PsiE family
BF28_577	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_5774	COG2274	protein secretion by the type I secretion system
BF28_5774	COG3271	cysteine-type peptidase activity
BF28_5775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_5776	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF28_5800	COG3344	reverse transcriptase
BF28_5827	COG2824	Alkylphosphonate utilization operon protein PhnA
BF28_583	COG0840	transmembrane signaling receptor activity
BF28_583	COG3290	protein histidine kinase activity
BF28_5830	COG0659	secondary active sulfate transmembrane transporter activity
BF28_5835	COG0463	Glycosyl transferase, family 2
BF28_5853	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_5854	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF28_5855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF28_5857	COG0384	phenazine biosynthesis protein PhzF
BF28_5860	COG0582	viral genome integration into host DNA
BF28_5864	COG2323	membrane
BF28_587	COG1252	NADH dehydrogenase
BF28_5874	COG0671	phosphoesterase, PA-phosphatase related
BF28_5881	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF28_5883	COG1408	metallophosphoesterase
BF28_5884	COG0726	polysaccharide deacetylase
BF28_5889	COG2226	methyltransferase
BF28_589	COG1733	regulation of RNA biosynthetic process
BF28_5893	COG3246	L-lysine catabolic process to acetate
BF28_5897	COG0840	transmembrane signaling receptor activity
BF28_590	COG2814	Major facilitator Superfamily
BF28_5909	COG4975	Glucose uptake
BF28_591	COG0656	L-ascorbic acid biosynthetic process
BF28_5910	COG0400	carboxylic ester hydrolase activity
BF28_5911	COG0346	lactoylglutathione lyase activity
BF28_5912	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF28_5913	COG0346	lactoylglutathione lyase activity
BF28_5914	COG1846	Transcriptional regulator
BF28_5916	COG2814	Major facilitator Superfamily
BF28_5919	COG1063	alcohol dehydrogenase
BF28_5920	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BF28_5921	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BF28_5922	COG2017	converts alpha-aldose to the beta-anomer
BF28_5923	COG2207	Transcriptional regulator
BF28_5924	COG5492	domain, Protein
BF28_5926	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BF28_5927	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_5927	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_5928	COG3716	PTS system mannose fructose sorbose family IID component
BF28_5929	COG3715	PTS system
BF28_5931	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_5932	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BF28_5933	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF28_5935	COG1414	Transcriptional regulator
BF28_5937	COG1988	membrane-bound metal-dependent
BF28_5939	COG0457	Tetratricopeptide repeat
BF28_594	COG2910	NAD(P)H-binding
BF28_5943	COG4978	Transcriptional regulator
BF28_5943	COG0789	Transcriptional regulator
BF28_5946	COG2801	Transposase and inactivated derivatives
BF28_595	COG1115	amino acid carrier protein
BF28_5950	COG1192	Involved in chromosome partitioning
BF28_596	COG1115	amino acid carrier protein
BF28_5969	COG0582	viral genome integration into host DNA
BF28_597	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_5973	COG2002	toxin-antitoxin pair type II binding
BF28_5979	COG2801	Transposase and inactivated derivatives
BF28_598	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_5981	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF28_5984	COG0730	response to heat
BF28_5986	COG4641	Protein conserved in bacteria
BF28_5989	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF28_5990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF28_5991	COG1121	(ABC) transporter
BF28_6019	COG1395	domain, Protein
BF28_602	COG1611	Belongs to the LOG family
BF28_6022	COG0582	viral genome integration into host DNA
BF28_605	COG0783	Belongs to the Dps family
BF28_606	COG1115	amino acid carrier protein
BF28_607	COG0490	domain, Protein
BF28_608	COG0475	glutathione-regulated potassium exporter activity
BF28_611	COG1741	Belongs to the pirin family
BF28_612	COG3227	Zinc metalloprotease (Elastase)
BF28_613	COG2151	metal-sulfur cluster biosynthetic enzyme
BF28_614	COG0840	transmembrane signaling receptor activity
BF28_619	COG5002	protein histidine kinase activity
BF28_620	COG0745	RESPONSE REGULATOR receiver
BF28_621	COG1376	ErfK ybiS ycfS ynhG family protein
BF28_623	COG0586	Pfam SNARE associated Golgi protein
BF28_629	COG1131	(ABC) transporter
BF28_631	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_632	COG0745	RESPONSE REGULATOR receiver
BF28_633	COG5002	protein histidine kinase activity
BF28_636	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_638	COG0706	membrane insertase activity
BF28_64	COG1358	cellular component organization or biogenesis
BF28_641	COG0531	amino acid
BF28_642	COG2814	Major facilitator Superfamily
BF28_646	COG0840	transmembrane signaling receptor activity
BF28_647	COG0011	TIGRFAM Protein of
BF28_650	COG1686	Belongs to the peptidase S11 family
BF28_652	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF28_652	COG1024	Enoyl-CoA hydratase
BF28_653	COG0183	Belongs to the thiolase family
BF28_654	COG1960	acyl-CoA dehydrogenase activity
BF28_655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_656	COG1309	transcriptional regulator
BF28_668	COG1393	Belongs to the ArsC family
BF28_67	COG2813	Specifically methylates the guanine in position
BF28_670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF28_671	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_674	COG2011	ABC-type metal ion transport system permease component
BF28_675	COG1464	Belongs to the NlpA lipoprotein family
BF28_676	COG1464	Belongs to the NlpA lipoprotein family
BF28_677	COG0396	ATPase activity
BF28_678	COG0719	Fe-S assembly protein
BF28_679	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF28_680	COG0822	iron-sulfur transferase activity
BF28_681	COG0719	Fe-S assembly protein
BF28_682	COG0737	Belongs to the 5'-nucleotidase family
BF28_683	COG3377	Domain of unknown function (DUF1805)
BF28_685	COG0739	heme binding
BF28_690	COG4377	Putative membrane peptidase family (DUF2324)
BF28_691	COG0789	Transcriptional regulator
BF28_693	COG4470	Protein conserved in bacteria
BF28_696	COG1494	fructose-1,6-bisphosphatase
BF28_697	COG2445	Protein of unknown function DUF86
BF28_699	COG0647	UMP catabolic process
BF28_701	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_703	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF28_704	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_706	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF28_707	COG4837	Protein of unknown function (DUF1462)
BF28_710	COG2824	Alkylphosphonate utilization operon protein PhnA
BF28_711	COG0390	transport system, permease component
BF28_712	COG2274	protein secretion by the type I secretion system
BF28_713	COG1252	NADH dehydrogenase
BF28_716	COG0316	Belongs to the HesB IscA family
BF28_719	COG1683	Conserved Protein
BF28_72	COG0250	Participates in transcription elongation, termination and antitermination
BF28_722	COG3708	Transcriptional regulator
BF28_725	COG1252	NADH dehydrogenase
BF28_728	COG3584	3D domain protein
BF28_73	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF28_731	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF28_732	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF28_733	COG1268	BioY protein
BF28_735	COG2050	protein possibly involved in aromatic compounds catabolism
BF28_736	COG0423	glycine-tRNA ligase activity
BF28_739	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_740	COG5018	Exonuclease
BF28_744	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF28_746	COG2267	carboxylic ester hydrolase activity
BF28_747	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF28_748	COG1522	sequence-specific DNA binding
BF28_749	COG0436	Aminotransferase
BF28_75	COG3688	RNA-binding protein containing a PIN domain
BF28_750	COG1098	S1 RNA binding domain
BF28_751	COG2155	Conserved Protein
BF28_753	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF28_755	COG1285	pathogenesis
BF28_76	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF28_763	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF28_782	COG0039	L-malate dehydrogenase activity
BF28_784	COG1404	Belongs to the peptidase S8 family
BF28_787	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF28_788	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF28_79	COG1045	serine acetyltransferase
BF28_790	COG0058	SHG alpha-glucan phosphorylase activity
BF28_794	COG1278	Cold shock
BF28_795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF28_796	COG1575	Belongs to the MenA family. Type 1 subfamily
BF28_797	COG1169	isochorismate synthase
BF28_799	COG0596	Alpha beta hydrolase
BF28_800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF28_802	COG4948	Mandelate Racemase Muconate Lactonizing
BF28_806	COG0590	tRNA wobble adenosine to inosine editing
BF28_807	COG2233	PERMEase
BF28_808	COG0583	DNA-binding transcription factor activity
BF28_809	COG3964	amidohydrolase
BF28_816	COG0577	efflux transmembrane transporter activity
BF28_817	COG1136	(ABC) transporter
BF28_818	COG0577	efflux transmembrane transporter activity
BF28_819	COG0577	efflux transmembrane transporter activity
BF28_820	COG2205	protein histidine kinase activity
BF28_821	COG0745	RESPONSE REGULATOR receiver
BF28_822	COG0640	Transcriptional regulator
BF28_823	COG5658	integral membrane protein
BF28_824	COG1131	(ABC) transporter
BF28_826	COG3708	Transcriptional regulator
BF28_826	COG2207	Transcriptional regulator
BF28_827	COG1136	(ABC) transporter
BF28_828	COG0577	efflux transmembrane transporter activity
BF28_83	COG4956	integral membrane protein (PIN domain superfamily)
BF28_832	COG0586	Pfam SNARE associated Golgi protein
BF28_838	COG1597	lipid kinase activity
BF28_844	COG0745	RESPONSE REGULATOR receiver
BF28_845	COG5002	protein histidine kinase activity
BF28_85	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF28_851	COG1842	Phage shock protein A
BF28_856	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_86	COG0542	response to heat
BF28_860	COG1294	oxidase, subunit
BF28_861	COG1271	oxidase subunit
BF28_863	COG0288	reversible hydration of carbon dioxide
BF28_867	COG0494	nUDIX hydrolase
BF28_872	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_873	COG1116	anion transmembrane transporter activity
BF28_874	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_877	COG1368	sulfuric ester hydrolase activity
BF28_878	COG2267	carboxylic ester hydrolase activity
BF28_879	COG4191	Histidine kinase
BF28_88	COG3880	PFAM UvrB UvrC protein
BF28_880	COG5002	protein histidine kinase activity
BF28_882	COG1349	DNA-binding transcription factor activity
BF28_883	COG0546	phosphoglycolate phosphatase activity
BF28_884	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF28_892	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_895	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF28_897	COG0438	transferase activity, transferring glycosyl groups
BF28_898	COG0671	phosphoesterase, PA-phosphatase related
BF28_899	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF28_900	COG2267	carboxylic ester hydrolase activity
BF28_904	COG5504	Zn-dependent protease
BF28_906	COG1794	racemase activity, acting on amino acids and derivatives
BF28_908	COG1131	(ABC) transporter
BF28_909	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF28_910	COG1242	4 iron, 4 sulfur cluster binding
BF28_914	COG1136	(ABC) transporter
BF28_916	COG0582	viral genome integration into host DNA
BF28_917	COG0490	domain, Protein
BF28_918	COG0475	glutathione-regulated potassium exporter activity
BF28_919	COG2814	Major facilitator Superfamily
BF28_927	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF28_929	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_933	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF28_934	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_936	COG0303	'Molybdopterin
BF28_937	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF28_938	COG0314	molybdopterin synthase activity
BF28_943	COG1329	Transcriptional regulator
BF28_947	COG3832	glyoxalase III activity
BF28_949	COG2814	Major facilitator Superfamily
BF28_950	COG2081	HI0933 family
BF28_951	COG2244	polysaccharide biosynthetic process
BF28_952	COG1187	pseudouridine synthase activity
BF28_953	COG1349	DNA-binding transcription factor activity
BF28_954	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_956	COG1523	belongs to the glycosyl hydrolase 13 family
BF28_957	COG0510	thiamine kinase activity
BF28_960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_962	COG1363	Peptidase, m42
BF28_963	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF28_964	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_966	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_968	COG1674	ftsk spoiiie
BF28_972	COG1695	Transcriptional regulator
BF28_973	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_977	COG2309	aminopeptidase activity
BF28_979	COG3118	belongs to the thioredoxin family
BF28_980	COG4851	CamS sex pheromone cAM373 precursor
BF28_982	COG1609	Transcriptional regulator
BF28_989	COG0666	response to abiotic stimulus
BF28_991	COG0745	RESPONSE REGULATOR receiver
BF28_993	COG2267	carboxylic ester hydrolase activity
BF28_994	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF28_995	COG0517	IMP dehydrogenase activity
BF28_996	COG0454	-acetyltransferase
BF28_997	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_999	COG1595	DNA-templated transcription, initiation