locus-tag	class	description
FORC21_0002	COG0592	DNA-directed DNA polymerase activity
FORC21_0003	COG2501	S4 domain
FORC21_0005	COG0187	DNA topoisomerase II activity
FORC21_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC21_0008	COG0516	GMP reductase activity
FORC21_0008	COG0517	IMP dehydrogenase activity
FORC21_0009	COG1686	Belongs to the peptidase S11 family
FORC21_0014	COG1428	Deoxynucleoside kinase
FORC21_0015	COG1428	Deoxynucleoside kinase
FORC21_0016	COG1335	isochorismatase
FORC21_0017	COG0590	tRNA wobble adenosine to inosine editing
FORC21_0018	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC21_0024	COG1982	Orn Lys Arg decarboxylase major
FORC21_0026	COG0470	DNA polymerase III
FORC21_0027	COG1774	PSP1 C-terminal conserved region
FORC21_0029	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC21_0031	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC21_0032	COG2002	toxin-antitoxin pair type II binding
FORC21_0035	COG0084	hydrolase, TatD family'
FORC21_0039	COG4466	Protein conserved in bacteria
FORC21_0042	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC21_0043	COG0251	oxidation-reduction process
FORC21_0046	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC21_0049	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC21_0050	COG2002	toxin-antitoxin pair type II binding
FORC21_0051	COG2244	polysaccharide biosynthetic process
FORC21_0052	COG3956	TIGRFAM MazG family protein
FORC21_0053	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC21_0057	COG1098	S1 RNA binding domain
FORC21_0058	COG2208	phosphoserine phosphatase activity
FORC21_0061	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC21_0064	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_0065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC21_0066	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC21_0067	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_0068	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC21_0069	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC21_0070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC21_0071	COG1396	sequence-specific DNA binding
FORC21_0072	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC21_0075	COG3880	PFAM UvrB UvrC protein
FORC21_0077	COG0542	response to heat
FORC21_0078	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC21_0080	COG4956	integral membrane protein (PIN domain superfamily)
FORC21_0084	COG1045	serine acetyltransferase
FORC21_0087	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC21_0088	COG3688	RNA-binding protein containing a PIN domain
FORC21_0090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC21_0091	COG0250	Participates in transcription elongation, termination and antitermination
FORC21_0096	COG2813	Specifically methylates the guanine in position
FORC21_0099	COG1358	cellular component organization or biogenesis
FORC21_0120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC21_0125	COG0201	protein transport
FORC21_0127	COG0024	Methionine aminopeptidase
FORC21_0129	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC21_0136	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FORC21_0141	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_0142	COG0489	protein tyrosine kinase activity
FORC21_0144	COG2194	sulfuric ester hydrolase activity
FORC21_0145	COG0726	polysaccharide deacetylase
FORC21_0149	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORC21_0150	COG4856	YbbR-like protein
FORC21_0157	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_0158	COG2011	ABC-type metal ion transport system permease component
FORC21_0159	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC21_0160	COG1464	Belongs to the NlpA lipoprotein family
FORC21_0161	COG0604	alcohol dehydrogenase
FORC21_0163	COG0277	FAD linked oxidase domain protein
FORC21_0164	COG2271	Major facilitator Superfamily
FORC21_0166	COG2814	Major facilitator Superfamily
FORC21_0169	COG0601	transmembrane transport
FORC21_0170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_0171	COG0444	Belongs to the ABC transporter superfamily
FORC21_0172	COG4608	Belongs to the ABC transporter superfamily
FORC21_0173	COG4166	transmembrane transport
FORC21_0174	COG4166	transmembrane transport
FORC21_0176	COG2207	Transcriptional regulator
FORC21_0179	COG4166	transmembrane transport
FORC21_0180	COG4166	transmembrane transport
FORC21_0181	COG0656	L-ascorbic acid biosynthetic process
FORC21_0185	COG4149	molybdate abc transporter
FORC21_0186	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC21_0187	COG1910	domain protein
FORC21_0191	COG0697	spore germination
FORC21_0194	COG0204	Acyl-transferase
FORC21_0196	COG1609	Transcriptional regulator
FORC21_0198	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_0202	COG5298	Protein conserved in bacteria
FORC21_0206	COG0488	(ABC) transporter
FORC21_0208	COG0747	negative chemotaxis
FORC21_0209	COG0601	transmembrane transport
FORC21_0211	COG0444	Belongs to the ABC transporter superfamily
FORC21_0212	COG4608	Belongs to the ABC transporter superfamily
FORC21_0213	COG0561	phosphatase activity
FORC21_0219	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORC21_0220	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC21_0222	COG0531	amino acid
FORC21_0223	COG2814	Major facilitator Superfamily
FORC21_0225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC21_0227	COG4294	response to UV
FORC21_0228	COG0705	Rhomboid family
FORC21_0230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC21_0231	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC21_0232	COG0864	Transcriptional regulator
FORC21_0233	COG2337	Toxic component of a toxin-antitoxin (TA) module
FORC21_0234	COG2183	response to ionizing radiation
FORC21_0236	COG0802	atpase or kinase
FORC21_0237	COG1214	PFAM Peptidase M22, glycoprotease
FORC21_0238	COG0456	acetyltransferase
FORC21_0240	COG0488	(ABC) transporter
FORC21_0243	COG1266	CAAX protease self-immunity
FORC21_0247	COG2252	PERMEase
FORC21_0249	COG5002	protein histidine kinase activity
FORC21_0251	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC21_0256	COG2205	protein histidine kinase activity
FORC21_0257	COG0745	RESPONSE REGULATOR receiver
FORC21_0260	COG2226	methyltransferase
FORC21_0262	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_0264	COG1215	transferase activity, transferring glycosyl groups
FORC21_0265	COG0697	spore germination
FORC21_0267	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC21_0268	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC21_0269	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC21_0271	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC21_0274	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC21_0276	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC21_0278	COG0151	Belongs to the GarS family
FORC21_0283	COG0210	DNA helicase
FORC21_0285	COG4851	CamS sex pheromone cAM373 precursor
FORC21_0288	COG1335	isochorismatase
FORC21_0290	COG2011	ABC-type metal ion transport system permease component
FORC21_0294	COG0003	Pfam Anion-transporting ATPase
FORC21_0295	COG1846	Transcriptional regulator
FORC21_0296	COG4682	membrane
FORC21_0300	COG1597	lipid kinase activity
FORC21_0302	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC21_0304	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_0305	COG2076	Multidrug Resistance protein
FORC21_0307	COG2309	aminopeptidase activity
FORC21_0311	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_0313	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC21_0316	COG4807	Protein conserved in bacteria
FORC21_0322	COG1473	amidohydrolase
FORC21_0325	COG0450	alkyl hydroperoxide reductase
FORC21_0326	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FORC21_0328	COG0235	Class ii aldolase
FORC21_0329	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_0330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_0331	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_0334	COG0166	Belongs to the GPI family
FORC21_0339	COG5002	protein histidine kinase activity
FORC21_0343	COG3541	Predicted nucleotidyltransferase
FORC21_0344	COG2814	Major facilitator Superfamily
FORC21_0345	COG2814	Major facilitator Superfamily
FORC21_0346	COG0723	plastoquinol--plastocyanin reductase activity
FORC21_0346	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_0348	COG0765	amino acid transport
FORC21_0349	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_0350	COG1126	abc transporter atp-binding protein
FORC21_0351	COG0840	transmembrane signaling receptor activity
FORC21_0356	COG0549	Belongs to the carbamate kinase family
FORC21_0357	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_0359	COG0277	FAD linked oxidase domain protein
FORC21_0360	COG0366	Alpha amylase catalytic
FORC21_0361	COG1263	PTS System
FORC21_0361	COG2190	(PTS) system
FORC21_0361	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_0367	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC21_0371	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_0372	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_0373	COG1116	anion transmembrane transporter activity
FORC21_0384	COG2270	Major facilitator Superfamily
FORC21_0390	COG2310	stress, protein
FORC21_0391	COG2310	stress, protein
FORC21_0392	COG2310	stress, protein
FORC21_0393	COG0861	Integral membrane protein TerC family
FORC21_0395	COG3853	Toxic anion resistance protein (TelA)
FORC21_0398	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC21_0400	COG1295	ribonuclease BN
FORC21_0401	COG2217	Heavy metal translocating P-type atpase
FORC21_0402	COG0697	spore germination
FORC21_0404	COG0681	Belongs to the peptidase S26 family
FORC21_0406	COG0586	Pfam SNARE associated Golgi protein
FORC21_0409	COG3871	stress protein (general stress protein 26)
FORC21_0410	COG0387	Pfam Sodium calcium exchanger
FORC21_0412	COG0535	radical SAM domain protein
FORC21_0416	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_0417	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC21_0420	COG3829	transcription factor binding
FORC21_0422	COG0833	amino acid
FORC21_0423	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_0429	COG1263	PTS System
FORC21_0429	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_0430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_0433	COG0463	Glycosyl transferase, family 2
FORC21_0435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_0435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC21_0439	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC21_0443	COG1228	amidohydrolase
FORC21_0444	COG1090	epimerase
FORC21_0450	COG1988	membrane-bound metal-dependent
FORC21_0451	COG1194	a g-specific adenine glycosylase
FORC21_0456	COG1132	(ABC) transporter
FORC21_0457	COG4129	membrane
FORC21_0458	COG0070	glutamate synthase
FORC21_0458	COG0067	glutamate synthase
FORC21_0458	COG0069	glutamate synthase activity
FORC21_0460	COG4555	ABC transporter
FORC21_0464	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC21_0465	COG0735	belongs to the Fur family
FORC21_0471	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC21_0475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC21_0478	COG2766	serine protein kinase
FORC21_0482	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_0484	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC21_0485	COG2268	Band 7 protein
FORC21_0487	COG3290	protein histidine kinase activity
FORC21_0488	COG4565	transcriptional regulatory protein
FORC21_0489	COG2851	Citrate transporter
FORC21_0494	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC21_0495	COG3842	ATPase activity
FORC21_0496	COG1175	transmembrane transport
FORC21_0497	COG0395	ABC-type sugar transport system, permease component
FORC21_0499	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC21_0500	COG0745	RESPONSE REGULATOR receiver
FORC21_0501	COG5002	protein histidine kinase activity
FORC21_0503	COG4990	cell redox homeostasis
FORC21_0505	COG3290	protein histidine kinase activity
FORC21_0506	COG4565	transcriptional regulatory protein
FORC21_0507	COG3493	citrate carrier protein
FORC21_0508	COG0281	malic enzyme
FORC21_0510	COG0697	spore germination
FORC21_0511	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_0513	COG5002	protein histidine kinase activity
FORC21_0517	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC21_0518	COG3383	formate dehydrogenase (NAD+) activity
FORC21_0519	COG2427	Protein of unknown function (DUF1641)
FORC21_0522	COG0531	amino acid
FORC21_0523	COG0640	Transcriptional regulator
FORC21_0524	COG2217	Heavy metal translocating P-type atpase
FORC21_0525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC21_0528	COG3227	Zinc metalloprotease (Elastase)
FORC21_0532	COG2720	vancomycin resistance protein
FORC21_0533	COG1316	TRANSCRIPTIONal
FORC21_0534	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_0535	COG0346	lactoylglutathione lyase activity
FORC21_0536	COG1253	flavin adenine dinucleotide binding
FORC21_0537	COG1027	Aspartate ammonia-lyase
FORC21_0538	COG1620	l-lactate permease
FORC21_0541	COG3104	oligopeptide transport
FORC21_0542	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_0543	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_0544	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_0548	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_0550	COG4548	von Willebrand factor, type A
FORC21_0551	COG0714	Associated with various cellular activities
FORC21_0555	COG0531	amino acid
FORC21_0556	COG2188	Transcriptional regulator
FORC21_0557	COG1263	PTS System
FORC21_0557	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_0558	COG0366	Alpha amylase catalytic
FORC21_0561	COG0697	spore germination
FORC21_0563	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC21_0564	COG1115	amino acid carrier protein
FORC21_0565	COG1126	abc transporter atp-binding protein
FORC21_0566	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_0567	COG0765	amino acid transport
FORC21_0568	COG0765	amino acid transport
FORC21_0569	COG0833	amino acid
FORC21_0574	COG2378	regulation of single-species biofilm formation
FORC21_0575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC21_0576	COG5002	protein histidine kinase activity
FORC21_0581	COG0659	secondary active sulfate transmembrane transporter activity
FORC21_0584	COG2271	Major facilitator Superfamily
FORC21_0585	COG1846	Transcriptional regulator
FORC21_0586	COG0477	Major facilitator Superfamily
FORC21_0587	COG1609	Transcriptional regulator
FORC21_0588	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC21_0591	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_0592	COG1879	ABC-type sugar transport system periplasmic component
FORC21_0596	COG1063	alcohol dehydrogenase
FORC21_0606	COG0840	transmembrane signaling receptor activity
FORC21_0607	COG1388	LysM domain
FORC21_0607	COG3584	3D domain protein
FORC21_0608	COG1476	TRANSCRIPTIONal
FORC21_0612	COG3104	oligopeptide transport
FORC21_0614	COG1114	Component of the transport system for branched-chain amino acids
FORC21_0617	COG1113	amino acid transport
FORC21_0618	COG2252	PERMEase
FORC21_0621	COG2153	protein acetylation
FORC21_0623	COG0475	glutathione-regulated potassium exporter activity
FORC21_0623	COG0569	domain protein
FORC21_0626	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC21_0628	COG0833	amino acid
FORC21_0629	COG4990	cell redox homeostasis
FORC21_0632	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_0633	COG0697	spore germination
FORC21_0634	COG0531	amino acid
FORC21_0636	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_0637	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_0638	COG1918	ferrous iron import across plasma membrane
FORC21_0638	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_0639	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC21_0640	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_0641	COG0581	inorganic phosphate transmembrane transporter activity
FORC21_0643	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC21_0644	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FORC21_0648	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC21_0649	COG1116	anion transmembrane transporter activity
FORC21_0650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_0651	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_0652	COG0352	thiamine-phosphate diphosphorylase activity
FORC21_0653	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_0654	COG2104	thiamine diphosphate biosynthetic process
FORC21_0656	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_0657	COG0351	phosphomethylpyrimidine kinase
FORC21_0664	COG2205	protein histidine kinase activity
FORC21_0665	COG2814	Major facilitator Superfamily
FORC21_0666	COG1846	Transcriptional regulator
FORC21_0671	COG1136	(ABC) transporter
FORC21_0674	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_0675	COG1129	ABC transporter
FORC21_0677	COG2252	PERMEase
FORC21_0678	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_0681	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC21_0682	COG1621	beta-fructofuranosidase activity
FORC21_0683	COG1263	PTS System
FORC21_0683	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_0684	COG1609	Transcriptional regulator
FORC21_0694	COG0778	Nitroreductase
FORC21_0695	COG2719	SpoVR family
FORC21_0697	COG1414	Transcriptional regulator
FORC21_0700	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC21_0701	COG1937	Protein conserved in bacteria
FORC21_0702	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_0702	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_0703	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_0703	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_0704	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_0705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_0705	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_0706	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_0707	COG2210	Belongs to the sulfur carrier protein TusA family
FORC21_0708	COG2210	Belongs to the sulfur carrier protein TusA family
FORC21_0709	COG0730	response to heat
FORC21_0711	COG1316	TRANSCRIPTIONal
FORC21_0712	COG0604	alcohol dehydrogenase
FORC21_0713	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC21_0716	COG3711	transcriptional antiterminator
FORC21_0716	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_0717	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_0718	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_0722	COG1388	LysM domain
FORC21_0722	COG3584	3D domain protein
FORC21_0723	COG0577	efflux transmembrane transporter activity
FORC21_0724	COG1136	(ABC) transporter
FORC21_0726	COG5522	Integral membrane protein (intg_mem_TP0381)
FORC21_0729	COG1114	Component of the transport system for branched-chain amino acids
FORC21_0730	COG3546	catalase activity
FORC21_0737	COG0586	Pfam SNARE associated Golgi protein
FORC21_0744	COG0531	amino acid
FORC21_0745	COG0475	glutathione-regulated potassium exporter activity
FORC21_0747	COG1737	Transcriptional regulator
FORC21_0749	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_0749	COG1263	PTS System
FORC21_0751	COG2259	Doxx family
FORC21_0755	COG1522	sequence-specific DNA binding
FORC21_0756	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC21_0756	COG0165	Argininosuccinate lyase
FORC21_0757	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_0759	COG2076	Multidrug Resistance protein
FORC21_0761	COG1309	transcriptional regulator
FORC21_0762	COG2814	Major facilitator Superfamily
FORC21_0763	COG1733	regulation of RNA biosynthetic process
FORC21_0765	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_0766	COG4533	DNA binding
FORC21_0767	COG2211	Major facilitator Superfamily
FORC21_0769	COG0693	protein deglycase activity
FORC21_0770	COG0693	protein deglycase activity
FORC21_0770	COG0753	catalase activity
FORC21_0772	COG0531	amino acid
FORC21_0773	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC21_0775	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_0776	COG1132	(ABC) transporter
FORC21_0777	COG1132	(ABC) transporter
FORC21_0778	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_0779	COG0765	amino acid transport
FORC21_0780	COG1126	abc transporter atp-binding protein
FORC21_0783	COG0189	ligase activity
FORC21_0787	COG4585	Histidine kinase
FORC21_0788	COG2197	response regulator
FORC21_0789	COG0028	Belongs to the TPP enzyme family
FORC21_0790	COG3527	Alpha-acetolactate decarboxylase
FORC21_0792	COG0561	phosphatase activity
FORC21_0794	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_0794	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_0795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC21_0796	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_0799	COG0659	secondary active sulfate transmembrane transporter activity
FORC21_0800	COG2244	polysaccharide biosynthetic process
FORC21_0804	COG1024	Enoyl-CoA hydratase
FORC21_0808	COG1363	Peptidase, m42
FORC21_0815	COG0601	transmembrane transport
FORC21_0816	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_0817	COG0444	Belongs to the ABC transporter superfamily
FORC21_0818	COG4608	Belongs to the ABC transporter superfamily
FORC21_0820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_0824	COG0457	Tetratricopeptide repeat
FORC21_0864	COG0477	Major facilitator Superfamily
FORC21_0865	COG3290	protein histidine kinase activity
FORC21_0866	COG4565	transcriptional regulatory protein
FORC21_0867	COG3181	Tripartite tricarboxylate transporter family receptor
FORC21_0868	COG0494	nUDIX hydrolase
FORC21_0870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FORC21_0877	COG0305	Participates in initiation and elongation during chromosome replication
FORC21_0882	COG0477	Major facilitator Superfamily
FORC21_0885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_0886	COG3344	reverse transcriptase
FORC21_0890	COG1073	alpha beta
FORC21_0899	COG1183	phosphatidylcholine synthase activity
FORC21_0902	COG2376	Dihydroxyacetone kinase
FORC21_0904	COG2376	Dihydroxyacetone kinase
FORC21_0911	COG1388	LysM domain
FORC21_0911	COG3584	3D domain protein
FORC21_0912	COG1388	LysM domain
FORC21_0912	COG0791	NLP P60 protein
FORC21_0914	COG2801	Transposase and inactivated derivatives
FORC21_0915	COG2373	Large extracellular alpha-helical protein
FORC21_0919	COG0596	Alpha beta hydrolase
FORC21_0926	COG3237	CsbD-like
FORC21_0931	COG1191	sigma factor activity
FORC21_0933	COG2208	phosphoserine phosphatase activity
FORC21_0934	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC21_0935	COG0784	Response regulator, receiver
FORC21_0935	COG2205	protein histidine kinase activity
FORC21_0935	COG5002	protein histidine kinase activity
FORC21_0940	COG0393	Putative heavy-metal-binding
FORC21_0944	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FORC21_0948	COG0420	3'-5' exonuclease activity
FORC21_0949	COG4717	serine-type aminopeptidase activity
FORC21_0951	COG0346	lactoylglutathione lyase activity
FORC21_0952	COG0346	lactoylglutathione lyase activity
FORC21_0953	COG0457	Tetratricopeptide repeat
FORC21_0955	COG2267	carboxylic ester hydrolase activity
FORC21_0960	COG2140	Oxalate decarboxylase
FORC21_0961	COG3620	sequence-specific DNA binding
FORC21_0962	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC21_0963	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC21_0965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC21_0966	COG1695	Transcriptional regulator
FORC21_0969	COG1595	DNA-templated transcription, initiation
FORC21_0972	COG3973	AAA domain
FORC21_0974	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC21_0978	COG4980	gas vesicle protein
FORC21_0979	COG0537	adenosine 5'-monophosphoramidase activity
FORC21_0980	COG1131	(ABC) transporter
FORC21_0981	COG4473	ABC transporter
FORC21_0986	COG3402	PFAM membrane-flanked domain
FORC21_0987	COG3428	Bacterial PH domain
FORC21_0993	COG0697	spore germination
FORC21_0994	COG3402	PFAM membrane-flanked domain
FORC21_0995	COG3428	Bacterial PH domain
FORC21_0996	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_0997	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_1007	COG1309	transcriptional regulator
FORC21_1008	COG1511	domain protein
FORC21_1012	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_1013	COG1609	Transcriptional regulator
FORC21_1015	COG1234	tRNA 3'-trailer cleavage
FORC21_1016	COG0095	Lipoate-protein ligase
FORC21_1018	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_1020	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC21_1022	COG4208	sulfate ABC transporter
FORC21_1056	COG1073	alpha beta
FORC21_1057	COG1408	metallophosphoesterase
FORC21_1058	COG1078	dGTPase activity
FORC21_1060	COG1595	DNA-templated transcription, initiation
FORC21_1061	COG3708	Transcriptional regulator
FORC21_1061	COG2207	Transcriptional regulator
FORC21_1062	COG2205	protein histidine kinase activity
FORC21_1063	COG0745	RESPONSE REGULATOR receiver
FORC21_1067	COG0501	Belongs to the peptidase M48B family
FORC21_1068	COG0840	transmembrane signaling receptor activity
FORC21_1069	COG3693	PFAM glycoside hydrolase, family 10
FORC21_1072	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC21_1073	COG2224	Isocitrate lyase
FORC21_1077	COG1278	Cold shock
FORC21_1081	COG0398	Pfam SNARE associated Golgi protein
FORC21_1093	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC21_1098	COG0367	asparagine synthase
FORC21_1100	COG0753	catalase activity
FORC21_1101	COG0004	ammonium transporteR
FORC21_1105	COG2996	Protein conserved in bacteria
FORC21_1119	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_1122	COG0561	phosphatase activity
FORC21_1126	COG2267	carboxylic ester hydrolase activity
FORC21_1130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC21_1131	COG5504	Zn-dependent protease
FORC21_1133	COG0180	Tryptophanyl-tRNA synthetase
FORC21_1135	COG4166	transmembrane transport
FORC21_1136	COG0601	transmembrane transport
FORC21_1137	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_1138	COG0444	Belongs to the ABC transporter superfamily
FORC21_1139	COG4608	Belongs to the ABC transporter superfamily
FORC21_1140	COG0534	Mate efflux family protein
FORC21_1141	COG4166	transmembrane transport
FORC21_1143	COG1393	Belongs to the ArsC family
FORC21_1144	COG0861	Integral membrane protein TerC family
FORC21_1148	COG1164	Oligoendopeptidase f
FORC21_1150	COG2346	COG2346, Truncated hemoglobins
FORC21_1151	COG4116	CYTH
FORC21_1153	COG2357	RelA SpoT domain protein
FORC21_1155	COG0564	pseudouridine synthase activity
FORC21_1158	COG0772	Belongs to the SEDS family
FORC21_1159	COG1216	Glycosyl transferase, family 2
FORC21_1163	COG0457	Tetratricopeptide repeat
FORC21_1163	COG0463	Glycosyl transferase, family 2
FORC21_1167	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC21_1170	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC21_1178	COG2153	protein acetylation
FORC21_1180	COG2382	esterase
FORC21_1184	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_1186	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC21_1186	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC21_1194	COG1620	l-lactate permease
FORC21_1195	COG5634	Uncharacterized conserved protein (DUF2278)
FORC21_1205	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_1207	COG1476	TRANSCRIPTIONal
FORC21_1229	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_1232	COG4152	abc transporter atp-binding protein
FORC21_1233	COG1668	transmembrane transport
FORC21_1238	COG1686	Belongs to the peptidase S11 family
FORC21_1239	COG0681	Belongs to the peptidase S26 family
FORC21_1246	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_1248	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC21_1249	COG1177	transmembrane transport
FORC21_1250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC21_1252	COG2409	Drug exporters of the RND superfamily
FORC21_1254	COG0564	pseudouridine synthase activity
FORC21_1256	COG2340	Cysteine-rich secretory protein family
FORC21_1257	COG0247	lactate metabolic process
FORC21_1258	COG0277	FAD linked oxidase domain protein
FORC21_1259	COG3835	regulator
FORC21_1261	COG0745	RESPONSE REGULATOR receiver
FORC21_1262	COG5002	protein histidine kinase activity
FORC21_1263	COG2186	Transcriptional regulator
FORC21_1267	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC21_1269	COG2116	formate transmembrane transporter activity
FORC21_1270	COG0861	Integral membrane protein TerC family
FORC21_1271	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_1273	COG2030	dehydratase
FORC21_1277	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_1278	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC21_1280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_1283	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC21_1284	COG3842	ATPase activity
FORC21_1289	COG1349	DNA-binding transcription factor activity
FORC21_1292	COG0235	Class ii aldolase
FORC21_1294	COG2861	carbohydrate metabolic process
FORC21_1296	COG3852	Histidine kinase
FORC21_1297	COG1846	Transcriptional regulator
FORC21_1299	COG2318	DinB family
FORC21_1301	COG5002	protein histidine kinase activity
FORC21_1303	COG0720	synthase
FORC21_1306	COG4873	Protein conserved in bacteria
FORC21_1312	COG1780	Probably involved in ribonucleotide reductase function
FORC21_1313	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC21_1314	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC21_1315	COG1725	Transcriptional regulator
FORC21_1316	COG1131	(ABC) transporter
FORC21_1318	COG1131	(ABC) transporter
FORC21_1322	COG1522	sequence-specific DNA binding
FORC21_1324	COG1335	isochorismatase
FORC21_1326	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_1327	COG2070	2-Nitropropane dioxygenase
FORC21_1328	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC21_1330	COG1696	Membrane protein involved in D-alanine export
FORC21_1335	COG0716	FMN binding
FORC21_1338	COG3173	Aminoglycoside phosphotransferase
FORC21_1345	COG1846	Transcriptional regulator
FORC21_1347	COG1301	dicarboxylic acid transport
FORC21_1348	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_1349	COG4709	membrane
FORC21_1350	COG3874	Sporulation protein YtfJ
FORC21_1354	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_1355	COG0028	Belongs to the TPP enzyme family
FORC21_1356	COG0440	acetolactate synthase activity
FORC21_1371	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC21_1374	COG1183	phosphatidylcholine synthase activity
FORC21_1375	COG1368	sulfuric ester hydrolase activity
FORC21_1376	COG1368	sulfuric ester hydrolase activity
FORC21_1378	COG0019	diaminopimelate decarboxylase activity
FORC21_1382	COG0529	Catalyzes the synthesis of activated sulfate
FORC21_1383	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC21_1387	COG1648	precorrin-2 dehydrogenase activity
FORC21_1388	COG0733	neurotransmitter:sodium symporter activity
FORC21_1393	COG1757	Na H antiporter
FORC21_1396	COG4758	membrane
FORC21_1397	COG4585	Histidine kinase
FORC21_1398	COG2197	response regulator
FORC21_1400	COG1114	Component of the transport system for branched-chain amino acids
FORC21_1410	COG0730	response to heat
FORC21_1411	COG0306	phosphate transporter
FORC21_1412	COG1392	Phosphate transport regulator
FORC21_1413	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_1416	COG3852	Histidine kinase
FORC21_1417	COG1801	Protein of unknown function DUF72
FORC21_1419	COG0582	viral genome integration into host DNA
FORC21_1420	COG5002	protein histidine kinase activity
FORC21_1423	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FORC21_1423	COG0392	lysyltransferase activity
FORC21_1424	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FORC21_1424	COG0392	lysyltransferase activity
FORC21_1427	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC21_1428	COG1686	Belongs to the peptidase S11 family
FORC21_1429	COG2715	membrane protein required for spore maturation
FORC21_1430	COG0700	Nucleoside recognition
FORC21_1431	COG1187	pseudouridine synthase activity
FORC21_1433	COG1333	cytochrome c biogenesis protein
FORC21_1434	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC21_1435	COG0745	RESPONSE REGULATOR receiver
FORC21_1436	COG5002	protein histidine kinase activity
FORC21_1437	COG2096	Adenosyltransferase
FORC21_1440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FORC21_1441	COG1141	Ferredoxin
FORC21_1443	COG0514	ATP-dependent DNA helicase (RecQ)
FORC21_1444	COG1266	CAAX protease self-immunity
FORC21_1446	COG1408	metallophosphoesterase
FORC21_1447	COG0789	Transcriptional regulator
FORC21_1449	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC21_1453	COG0492	ferredoxin-NADP+ reductase activity
FORC21_1454	COG0252	asparaginase activity
FORC21_1468	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_1471	COG0142	geranyltranstransferase activity
FORC21_1473	COG0142	geranyltranstransferase activity
FORC21_1478	COG0457	Tetratricopeptide repeat
FORC21_1482	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC21_1483	COG2010	Cytochrome c
FORC21_1483	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC21_1484	COG4347	Protein of unknown function (DUF1405)
FORC21_1487	COG2738	Putative neutral zinc metallopeptidase
FORC21_1489	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_1490	COG1694	Mazg nucleotide pyrophosphohydrolase
FORC21_1494	COG0438	transferase activity, transferring glycosyl groups
FORC21_1502	COG1199	ATP-dependent helicase activity
FORC21_1502	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC21_1506	COG3935	DnaD domain protein
FORC21_1507	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC21_1509	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_1509	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_1520	COG0116	Belongs to the methyltransferase superfamily
FORC21_1522	COG1199	ATP-dependent helicase activity
FORC21_1523	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC21_1525	COG0024	Methionine aminopeptidase
FORC21_1527	COG2233	PERMEase
FORC21_1528	COG2311	Membrane
FORC21_1529	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_1531	COG0456	acetyltransferase
FORC21_1539	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_1542	COG3944	biosynthesis protein
FORC21_1544	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC21_1547	COG1215	transferase activity, transferring glycosyl groups
FORC21_1548	COG0438	transferase activity, transferring glycosyl groups
FORC21_1551	COG0454	-acetyltransferase
FORC21_1555	COG0328	RNA-DNA hybrid ribonuclease activity
FORC21_1562	COG3403	YqcI/YcgG family
FORC21_1563	COG1280	lysine exporter protein (LysE YggA)
FORC21_1567	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_1568	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_1570	COG0475	glutathione-regulated potassium exporter activity
FORC21_1571	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_1572	COG0789	Transcriptional regulator
FORC21_1572	COG4978	Transcriptional regulator
FORC21_1574	COG2323	membrane
FORC21_1575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC21_1583	COG1923	regulation of RNA biosynthetic process
FORC21_1585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC21_1586	COG1360	Flagellar Motor Protein
FORC21_1587	COG2201	protein-glutamate methylesterase activity
FORC21_1588	COG0643	Histidine kinase
FORC21_1588	COG2198	Histidine kinase
FORC21_1589	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_1589	COG1776	CheC inhibitor of MCP methylation
FORC21_1592	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC21_1596	COG1256	bacterial-type flagellum assembly
FORC21_1597	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC21_1601	COG1815	bacterial-type flagellum-dependent cell motility
FORC21_1602	COG1558	bacterial-type flagellum-dependent cell motility
FORC21_1603	COG1677	Flagellar hook-basal body complex protein FliE
FORC21_1604	COG1766	The M ring may be actively involved in energy transduction
FORC21_1605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_1607	COG1157	protein secretion by the type III secretion system
FORC21_1611	COG1749	Flagellar hook protein flgE
FORC21_1614	COG0784	Response regulator, receiver
FORC21_1614	COG0835	chemotaxis
FORC21_1616	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC21_1618	COG0741	lytic transglycosylase activity
FORC21_1620	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_1621	COG1776	CheC inhibitor of MCP methylation
FORC21_1621	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_1623	COG1338	Plays a role in the flagellum-specific transport system
FORC21_1624	COG1987	bacterial-type flagellum assembly
FORC21_1626	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC21_1627	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC21_1628	COG1419	protein localization to endoplasmic reticulum
FORC21_1629	COG4786	Flagellar basal body rod
FORC21_1630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC21_1637	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_1643	COG3842	ATPase activity
FORC21_1645	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC21_1646	COG1177	transmembrane transport
FORC21_1652	COG0406	alpha-ribazole phosphatase activity
FORC21_1658	COG0367	asparagine synthase
FORC21_1664	COG1802	Transcriptional regulator
FORC21_1665	COG0697	spore germination
FORC21_1667	COG0523	cobalamin synthesis protein
FORC21_1668	COG0701	Predicted permease
FORC21_1671	COG1757	Na H antiporter
FORC21_1672	COG0789	Transcriptional regulator
FORC21_1677	COG0534	Mate efflux family protein
FORC21_1678	COG3340	Belongs to the peptidase S51 family
FORC21_1682	COG0785	Cytochrome C biogenesis protein
FORC21_1683	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_1686	COG0457	Tetratricopeptide repeat
FORC21_1689	COG2733	membrane
FORC21_1696	COG1131	(ABC) transporter
FORC21_1699	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_1700	COG0528	UMP kinase activity
FORC21_1703	COG1027	Aspartate ammonia-lyase
FORC21_1704	COG0281	malic enzyme
FORC21_1705	COG4191	Histidine kinase
FORC21_1706	COG0784	Response regulator, receiver
FORC21_1707	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_1716	COG2814	Major facilitator Superfamily
FORC21_1719	COG1695	Transcriptional regulator
FORC21_1721	COG0477	Major facilitator Superfamily
FORC21_1725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC21_1726	COG2223	nitrite transmembrane transporter activity
FORC21_1727	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_1731	COG0733	neurotransmitter:sodium symporter activity
FORC21_1733	COG5566	PFAM Mor transcription activator
FORC21_1734	COG2323	membrane
FORC21_1739	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_1741	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_1742	COG0028	Belongs to the TPP enzyme family
FORC21_1746	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC21_1751	COG2814	Major facilitator Superfamily
FORC21_1752	COG3384	dioxygenase
FORC21_1754	COG3279	Response regulator of the LytR AlgR family
FORC21_1755	COG0427	acetyl-CoA hydrolase
FORC21_1759	COG4166	transmembrane transport
FORC21_1763	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_1767	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC21_1770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC21_1772	COG0531	amino acid
FORC21_1778	COG2309	aminopeptidase activity
FORC21_1781	COG0456	acetyltransferase
FORC21_1784	COG1309	transcriptional regulator
FORC21_1785	COG2390	Transcriptional regulator
FORC21_1787	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_1788	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC21_1790	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC21_1792	COG0006	proline dipeptidase activity
FORC21_1794	COG2132	Multicopper oxidase
FORC21_1800	COG1114	Component of the transport system for branched-chain amino acids
FORC21_1802	COG2372	response to copper ion
FORC21_1802	COG1276	copper resistance
FORC21_1803	COG4549	nuclear export factor GLE1
FORC21_1804	COG0697	spore germination
FORC21_1805	COG0583	DNA-binding transcription factor activity
FORC21_1806	COG1959	2 iron, 2 sulfur cluster binding
FORC21_1807	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC21_1808	COG0778	Nitroreductase
FORC21_1811	COG0628	permease
FORC21_1813	COG1231	oxidoreductase activity
FORC21_1814	COG0523	cobalamin synthesis protein
FORC21_1816	COG0411	ABC transporter
FORC21_1818	COG0559	Belongs to the binding-protein-dependent transport system permease family
FORC21_1820	COG0583	DNA-binding transcription factor activity
FORC21_1826	COG1271	oxidase subunit
FORC21_1827	COG1294	oxidase, subunit
FORC21_1828	COG4988	ABC transporter
FORC21_1829	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC21_1831	COG1216	Glycosyl transferase, family 2
FORC21_1839	COG1686	Belongs to the peptidase S11 family
FORC21_1842	COG1388	LysM domain
FORC21_1842	COG0791	NLP P60 protein
FORC21_1844	COG1132	(ABC) transporter
FORC21_1845	COG0745	RESPONSE REGULATOR receiver
FORC21_1846	COG5002	protein histidine kinase activity
FORC21_1848	COG0300	oxidoreductase activity
FORC21_1850	COG0726	polysaccharide deacetylase
FORC21_1854	COG0460	homoserine dehydrogenase
FORC21_1859	COG1316	TRANSCRIPTIONal
FORC21_1861	COG0745	RESPONSE REGULATOR receiver
FORC21_1862	COG5002	protein histidine kinase activity
FORC21_1863	COG0726	polysaccharide deacetylase
FORC21_1865	COG1285	pathogenesis
FORC21_1866	COG1247	-acetyltransferase
FORC21_1868	COG4264	IucA IucC family
FORC21_1869	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_1872	COG1082	Xylose isomerase domain protein TIM barrel
FORC21_1874	COG2814	Major facilitator Superfamily
FORC21_1875	COG1279	arginine transmembrane transporter activity
FORC21_1876	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_1878	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC21_1885	COG0577	efflux transmembrane transporter activity
FORC21_1886	COG2002	toxin-antitoxin pair type II binding
FORC21_1887	COG1404	Belongs to the peptidase S8 family
FORC21_1888	COG0640	Transcriptional regulator
FORC21_1889	COG0667	Aldo Keto reductase
FORC21_1890	COG2814	Major facilitator Superfamily
FORC21_1892	COG3152	Membrane
FORC21_1897	COG0840	transmembrane signaling receptor activity
FORC21_1900	COG3949	Membrane
FORC21_1901	COG0783	Belongs to the Dps family
FORC21_1904	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_1906	COG1231	oxidoreductase activity
FORC21_1907	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_1908	COG4989	oxidoreductase activity
FORC21_1909	COG0523	cobalamin synthesis protein
FORC21_1910	COG0456	acetyltransferase
FORC21_1911	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC21_1913	COG0702	epimerase
FORC21_1915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_1917	COG4166	transmembrane transport
FORC21_1922	COG5337	Spore coat protein CotH
FORC21_1923	COG1051	belongs to the nudix hydrolase family
FORC21_1924	COG0586	Pfam SNARE associated Golgi protein
FORC21_1925	COG2244	polysaccharide biosynthetic process
FORC21_1927	COG0701	Predicted permease
FORC21_1928	COG3689	TIGRFAM TIGR03943 family protein
FORC21_1929	COG1607	acyl-coa hydrolase
FORC21_1930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_1933	COG0702	epimerase
FORC21_1934	COG2839	Protein conserved in bacteria
FORC21_1935	COG1253	flavin adenine dinucleotide binding
FORC21_1938	COG1114	Component of the transport system for branched-chain amino acids
FORC21_1939	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC21_1943	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_1945	COG1876	peptidase activity
FORC21_1947	COG0154	amidase activity
FORC21_1948	COG2211	Major facilitator Superfamily
FORC21_1951	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_1953	COG0561	phosphatase activity
FORC21_1956	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC21_1959	COG1819	glycosyl
FORC21_1960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_1961	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_1967	COG0456	acetyltransferase
FORC21_1972	COG0842	Transport permease protein
FORC21_1972	COG1511	domain protein
FORC21_1975	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_2002	COG3874	Sporulation protein YtfJ
FORC21_2007	COG2226	methyltransferase
FORC21_2012	COG0346	lactoylglutathione lyase activity
FORC21_2014	COG0604	alcohol dehydrogenase
FORC21_2015	COG1595	DNA-templated transcription, initiation
FORC21_2017	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC21_2019	COG0426	domain, Protein
FORC21_2019	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC21_2021	COG0386	Belongs to the glutathione peroxidase family
FORC21_2022	COG1305	Transglutaminase-like
FORC21_2023	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FORC21_2024	COG0714	Associated with various cellular activities
FORC21_2025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FORC21_2026	COG1140	nitrate reductase beta subunit
FORC21_2027	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FORC21_2028	COG2181	nitrate reductase activity
FORC21_2029	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_2030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC21_2031	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_2032	COG0303	'Molybdopterin
FORC21_2033	COG0314	molybdopterin synthase activity
FORC21_2035	COG2223	nitrite transmembrane transporter activity
FORC21_2038	COG1648	precorrin-2 dehydrogenase activity
FORC21_2040	COG1587	Uroporphyrinogen-III synthase
FORC21_2040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC21_2041	COG2146	nitrite reductase [NAD(P)H] activity
FORC21_2042	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC21_2043	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FORC21_2050	COG2359	stage V sporulation protein S
FORC21_2056	COG4974	Belongs to the 'phage' integrase family
FORC21_2061	COG0457	Tetratricopeptide repeat
FORC21_2064	COG1418	mRNA catabolic process
FORC21_2065	COG0488	(ABC) transporter
FORC21_2068	COG0629	single-stranded DNA binding
FORC21_2069	COG1413	lyase activity
FORC21_2072	COG2521	methyltransferase
FORC21_2072	COG2136	Putative SAM-dependent methyltransferase
FORC21_2073	COG0018	arginyl-trna synthetase
FORC21_2081	COG0017	Asparaginyl-tRNA synthetase
FORC21_2082	COG1929	Belongs to the glycerate kinase type-1 family
FORC21_2084	COG0745	RESPONSE REGULATOR receiver
FORC21_2085	COG5002	protein histidine kinase activity
FORC21_2085	COG3850	Histidine kinase
FORC21_2088	COG0733	neurotransmitter:sodium symporter activity
FORC21_2096	COG2610	gluconate transmembrane transporter activity
FORC21_2098	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_2100	COG0456	acetyltransferase
FORC21_2102	COG3655	Transcriptional regulator
FORC21_2103	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC21_2105	COG1131	(ABC) transporter
FORC21_2106	COG4473	ABC transporter
FORC21_2108	COG0546	phosphoglycolate phosphatase activity
FORC21_2111	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_2114	COG0768	penicillin binding
FORC21_2116	COG0204	Acyl-transferase
FORC21_2117	COG1272	protein, Hemolysin III
FORC21_2119	COG0805	protein transport
FORC21_2121	COG1307	EDD domain protein, DegV family
FORC21_2123	COG1999	signal sequence binding
FORC21_2124	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC21_2125	COG0367	asparagine synthase
FORC21_2128	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_2129	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_2130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_2133	COG1335	isochorismatase
FORC21_2135	COG0668	transmembrane transport
FORC21_2136	COG4585	Histidine kinase
FORC21_2136	COG2203	Gaf domain
FORC21_2137	COG2197	response regulator
FORC21_2138	COG1737	Transcriptional regulator
FORC21_2139	COG0384	phenazine biosynthesis protein PhzF
FORC21_2140	COG1064	alcohol dehydrogenase
FORC21_2146	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC21_2153	COG1125	glycine betaine transport
FORC21_2153	COG0517	IMP dehydrogenase activity
FORC21_2154	COG1174	glycine betaine transport
FORC21_2161	COG1253	flavin adenine dinucleotide binding
FORC21_2162	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_2163	COG5506	Protein of unknown function (DUF1694)
FORC21_2166	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_2167	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC21_2168	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FORC21_2169	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_2170	COG0456	acetyltransferase
FORC21_2171	COG3829	transcription factor binding
FORC21_2172	COG1509	lysine 2,3-aminomutase activity
FORC21_2179	COG3064	Membrane
FORC21_2179	COG0515	serine threonine protein kinase
FORC21_2179	COG4991	sh3 domain protein
FORC21_2181	COG0671	phosphoesterase, PA-phosphatase related
FORC21_2182	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC21_2183	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_2201	COG0300	oxidoreductase activity
FORC21_2205	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_2205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_2207	COG2814	Major facilitator Superfamily
FORC21_2208	COG4841	protein insertion into membrane
FORC21_2209	COG0372	Belongs to the citrate synthase family
FORC21_2210	COG2079	MmgE PrpD family protein
FORC21_2211	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC21_2212	COG1960	acyl-CoA dehydrogenase activity
FORC21_2213	COG2084	Dehydrogenase
FORC21_2215	COG1280	lysine exporter protein (LysE YggA)
FORC21_2216	COG1024	Enoyl-CoA hydratase
FORC21_2219	COG0420	3'-5' exonuclease activity
FORC21_2220	COG0419	ATPase involved in DNA repair
FORC21_2225	COG2223	nitrite transmembrane transporter activity
FORC21_2226	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_2227	COG1169	isochorismate synthase
FORC21_2228	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC21_2229	COG3433	isochorismatase activity
FORC21_2229	COG1535	isochorismatase
FORC21_2230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC21_2231	COG3251	PFAM MbtH domain protein
FORC21_2232	COG2814	Major facilitator Superfamily
FORC21_2235	COG0776	regulation of translation
FORC21_2237	COG2318	DinB family
FORC21_2239	COG1115	amino acid carrier protein
FORC21_2243	COG1187	pseudouridine synthase activity
FORC21_2244	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC21_2245	COG1136	(ABC) transporter
FORC21_2253	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_2255	COG2267	carboxylic ester hydrolase activity
FORC21_2257	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_2262	COG1247	-acetyltransferase
FORC21_2269	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_2275	COG0583	DNA-binding transcription factor activity
FORC21_2276	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC21_2280	COG0583	DNA-binding transcription factor activity
FORC21_2281	COG2258	MOSC domain
FORC21_2284	COG1132	(ABC) transporter
FORC21_2285	COG1132	(ABC) transporter
FORC21_2290	COG1396	sequence-specific DNA binding
FORC21_2296	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_2297	COG1595	DNA-templated transcription, initiation
FORC21_2303	COG1649	PFAM Uncharacterised BCR, COG1649
FORC21_2308	COG2971	BadF BadG BcrA BcrD
FORC21_2310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC21_2312	COG1846	Transcriptional regulator
FORC21_2317	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_2321	COG1309	transcriptional regulator
FORC21_2325	COG3615	Tellurite resistance protein tehB
FORC21_2325	COG0500	methyltransferase
FORC21_2327	COG2226	methyltransferase
FORC21_2328	COG3961	Belongs to the TPP enzyme family
FORC21_2329	COG1846	Transcriptional regulator
FORC21_2335	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC21_2340	COG2002	toxin-antitoxin pair type II binding
FORC21_2342	COG0730	response to heat
FORC21_2343	COG0110	maltose O-acetyltransferase activity
FORC21_2344	COG1686	Belongs to the peptidase S11 family
FORC21_2346	COG2814	Major facilitator Superfamily
FORC21_2354	COG2312	Erythromycin esterase
FORC21_2355	COG0741	lytic transglycosylase activity
FORC21_2356	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_2362	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_2363	COG0768	penicillin binding
FORC21_2364	COG1595	DNA-templated transcription, initiation
FORC21_2366	COG0768	penicillin binding
FORC21_2369	COG1408	metallophosphoesterase
FORC21_2371	COG1131	(ABC) transporter
FORC21_2373	COG1309	transcriptional regulator
FORC21_2376	COG1960	acyl-CoA dehydrogenase activity
FORC21_2377	COG0439	Biotin carboxylase
FORC21_2378	COG0511	ligase activity, forming carbon-carbon bonds
FORC21_2379	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC21_2380	COG1024	Enoyl-CoA hydratase
FORC21_2381	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC21_2382	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_2388	COG1686	Belongs to the peptidase S11 family
FORC21_2393	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC21_2396	COG3227	Zinc metalloprotease (Elastase)
FORC21_2397	COG2207	Transcriptional regulator
FORC21_2403	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC21_2405	COG2814	Major facilitator Superfamily
FORC21_2406	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_2407	COG1733	regulation of RNA biosynthetic process
FORC21_2417	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_2420	COG1063	alcohol dehydrogenase
FORC21_2422	COG2323	membrane
FORC21_2423	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC21_2425	COG3386	PFAM SMP-30 Gluconolaconase
FORC21_2427	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FORC21_2428	COG3773	Cell wall hydrolase
FORC21_2430	COG0745	RESPONSE REGULATOR receiver
FORC21_2431	COG2205	protein histidine kinase activity
FORC21_2435	COG1136	(ABC) transporter
FORC21_2436	COG0577	efflux transmembrane transporter activity
FORC21_2440	COG0460	homoserine dehydrogenase
FORC21_2441	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_2443	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC21_2454	COG2124	cytochrome p450
FORC21_2458	COG2124	cytochrome p450
FORC21_2463	COG0561	phosphatase activity
FORC21_2464	COG5002	protein histidine kinase activity
FORC21_2467	COG1819	glycosyl
FORC21_2468	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_2472	COG2205	protein histidine kinase activity
FORC21_2485	COG0604	alcohol dehydrogenase
FORC21_2486	COG0671	phosphoesterase, PA-phosphatase related
FORC21_2498	COG2814	Major facilitator Superfamily
FORC21_2502	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_2506	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_2507	COG0697	spore germination
FORC21_2516	COG2223	nitrite transmembrane transporter activity
FORC21_2520	COG0592	DNA-directed DNA polymerase activity
FORC21_2524	COG0251	oxidation-reduction process
FORC21_2525	COG3878	Protein conserved in bacteria
FORC21_2529	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC21_2538	COG0322	excinuclease ABC activity
FORC21_2544	COG1131	(ABC) transporter
FORC21_2548	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_2559	COG1073	alpha beta
FORC21_2560	COG1523	belongs to the glycosyl hydrolase 13 family
FORC21_2561	COG3227	Zinc metalloprotease (Elastase)
FORC21_2562	COG0737	Belongs to the 5'-nucleotidase family
FORC21_2566	COG0201	protein transport
FORC21_2567	COG0697	spore germination
FORC21_2568	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_2570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC21_2576	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_2579	COG2959	enzyme of heme biosynthesis
FORC21_2580	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_2580	COG3773	Cell wall hydrolase
FORC21_2587	COG1309	transcriptional regulator
FORC21_2592	COG3284	Transcriptional regulator
FORC21_2595	COG1349	DNA-binding transcription factor activity
FORC21_2598	COG1959	2 iron, 2 sulfur cluster binding
FORC21_2601	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_2602	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_2603	COG0022	dehydrogenase e1 component
FORC21_2604	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_2607	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_2613	COG4176	ABC-type proline glycine betaine transport system permease component
FORC21_2614	COG4175	Glycine betaine
FORC21_2614	COG0517	IMP dehydrogenase activity
FORC21_2620	COG2153	protein acetylation
FORC21_2621	COG3397	chitin binding
FORC21_2622	COG1819	glycosyl
FORC21_2626	COG2205	protein histidine kinase activity
FORC21_2627	COG2226	methyltransferase
FORC21_2628	COG2315	Protein conserved in bacteria
FORC21_2638	COG3973	AAA domain
FORC21_2641	COG0514	ATP-dependent DNA helicase (RecQ)
FORC21_2646	COG4637	Psort location Cytoplasmic, score
FORC21_2650	COG3397	chitin binding
FORC21_2653	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC21_2654	COG1115	amino acid carrier protein
FORC21_2655	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_2656	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC21_2658	COG3938	Belongs to the proline racemase family
FORC21_2659	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_2667	COG1078	dGTPase activity
FORC21_2668	COG0586	Pfam SNARE associated Golgi protein
FORC21_2670	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC21_2672	COG4166	transmembrane transport
FORC21_2674	COG4948	Mandelate Racemase Muconate Lactonizing
FORC21_2677	COG0667	Aldo Keto reductase
FORC21_2687	COG5002	protein histidine kinase activity
FORC21_2687	COG3850	Histidine kinase
FORC21_2688	COG0745	RESPONSE REGULATOR receiver
FORC21_2696	COG1164	Oligoendopeptidase f
FORC21_2697	COG1307	EDD domain protein, DegV family
FORC21_2705	COG2814	Major facilitator Superfamily
FORC21_2707	COG1664	Polymer-forming cytoskeletal
FORC21_2708	COG0789	Transcriptional regulator
FORC21_2709	COG4533	DNA binding
FORC21_2710	COG0477	Major facilitator Superfamily
FORC21_2710	COG2814	Major facilitator Superfamily
FORC21_2714	COG2261	transglycosylase associated protein
FORC21_2717	COG2226	methyltransferase
FORC21_2726	COG0436	Aminotransferase
FORC21_2727	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC21_2737	COG0628	permease
FORC21_2739	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_2740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_2741	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_2750	COG2746	aminoglycoside 3-N-acetyltransferase activity
FORC21_2752	COG0697	spore germination
FORC21_2754	COG2318	DinB family
FORC21_2758	COG4912	Dna alkylation repair
FORC21_2760	COG0346	lactoylglutathione lyase activity
FORC21_2761	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_2762	COG0726	polysaccharide deacetylase
FORC21_2764	COG0861	Integral membrane protein TerC family
FORC21_2765	COG1368	sulfuric ester hydrolase activity
FORC21_2766	COG0488	(ABC) transporter
FORC21_2768	COG2409	Drug exporters of the RND superfamily
FORC21_2768	COG1033	growth of symbiont in host cell
FORC21_2769	COG1309	transcriptional regulator
FORC21_2772	COG0287	Prephenate dehydrogenase
FORC21_2775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC21_2775	COG1605	Chorismate mutase
FORC21_2783	COG3584	3D domain protein
FORC21_2783	COG1388	LysM domain
FORC21_2785	COG0346	lactoylglutathione lyase activity
FORC21_2788	COG1309	transcriptional regulator
FORC21_2791	COG1879	ABC-type sugar transport system periplasmic component
FORC21_2792	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_2793	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_2795	COG2390	Transcriptional regulator
FORC21_2796	COG1070	Carbohydrate kinase
FORC21_2800	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_2804	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_2807	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_2808	COG4187	Peptidase family M20/M25/M40
FORC21_2809	COG1414	Transcriptional regulator
FORC21_2810	COG0833	amino acid
FORC21_2812	COG3239	Fatty acid desaturase
FORC21_2814	COG2720	vancomycin resistance protein
FORC21_2815	COG1785	Belongs to the alkaline phosphatase family
FORC21_2817	COG3655	Transcriptional regulator
FORC21_2821	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_2822	COG0346	lactoylglutathione lyase activity
FORC21_2827	COG0714	Associated with various cellular activities
FORC21_2832	COG0463	Glycosyl transferase, family 2
FORC21_2839	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC21_2840	COG0753	catalase activity
FORC21_2849	COG0714	Associated with various cellular activities
FORC21_2872	COG0778	Nitroreductase
FORC21_2873	COG1846	Transcriptional regulator
FORC21_2877	COG3831	ATPase activity
FORC21_2877	COG4884	unkown
FORC21_2880	COG1136	(ABC) transporter
FORC21_2885	COG0456	acetyltransferase
FORC21_2888	COG0697	spore germination
FORC21_2889	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_2898	COG0730	response to heat
FORC21_2900	COG0833	amino acid
FORC21_2902	COG4335	DNA alkylation repair
FORC21_2915	COG1984	allophanate hydrolase subunit 2
FORC21_2916	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC21_2917	COG1414	Transcriptional regulator
FORC21_2919	COG3142	Participates in the control of copper homeostasis
FORC21_2920	COG0640	Transcriptional regulator
FORC21_2922	COG1960	acyl-CoA dehydrogenase activity
FORC21_2930	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FORC21_2936	COG0574	Belongs to the PEP-utilizing enzyme family
FORC21_2936	COG3848	Pyruvate phosphate dikinase
FORC21_2937	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_2941	COG1063	alcohol dehydrogenase
FORC21_2943	COG1027	Aspartate ammonia-lyase
FORC21_2944	COG0252	asparaginase activity
FORC21_2945	COG1396	sequence-specific DNA binding
FORC21_2949	COG5002	protein histidine kinase activity
FORC21_2954	COG2207	Transcriptional regulator
FORC21_2956	COG0322	excinuclease ABC activity
FORC21_2957	COG0531	amino acid
FORC21_2958	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_2960	COG0531	amino acid
FORC21_2961	COG0697	spore germination
FORC21_2962	COG0784	Response regulator, receiver
FORC21_2963	COG4191	Histidine kinase
FORC21_2964	COG2066	Belongs to the glutaminase family
FORC21_2966	COG1115	amino acid carrier protein
FORC21_2968	COG2124	cytochrome p450
FORC21_2971	COG0737	Belongs to the 5'-nucleotidase family
FORC21_2972	COG2267	carboxylic ester hydrolase activity
FORC21_2973	COG1335	isochorismatase
FORC21_2977	COG0583	DNA-binding transcription factor activity
FORC21_2978	COG1846	Transcriptional regulator
FORC21_2979	COG0598	Magnesium transport protein CorA
FORC21_2983	COG1073	alpha beta
FORC21_2987	COG0415	Belongs to the DNA photolyase family
FORC21_2990	COG0288	reversible hydration of carbon dioxide
FORC21_2992	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC21_2993	COG5609	conserved protein (DUF2294)
FORC21_2996	COG0697	spore germination
FORC21_2997	COG0726	polysaccharide deacetylase
FORC21_2999	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC21_3004	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_3006	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3006	COG3347	Dehydrogenase
FORC21_3008	COG1070	Carbohydrate kinase
FORC21_3009	COG0235	Class ii aldolase
FORC21_3011	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_3013	COG4154	Belongs to the RbsD FucU family
FORC21_3016	COG0798	PFAM Bile acid sodium symporter
FORC21_3017	COG0346	lactoylglutathione lyase activity
FORC21_3018	COG0640	Transcriptional regulator
FORC21_3020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC21_3021	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC21_3021	COG3320	Male sterility
FORC21_3023	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3024	COG1522	sequence-specific DNA binding
FORC21_3029	COG0346	lactoylglutathione lyase activity
FORC21_3038	COG1309	transcriptional regulator
FORC21_3049	COG0745	RESPONSE REGULATOR receiver
FORC21_3050	COG3850	Histidine kinase
FORC21_3050	COG5002	protein histidine kinase activity
FORC21_3060	COG2814	Major facilitator Superfamily
FORC21_3064	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC21_3067	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC21_3071	COG0577	efflux transmembrane transporter activity
FORC21_3075	COG3850	Histidine kinase
FORC21_3075	COG5002	protein histidine kinase activity
FORC21_3077	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_3082	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_3086	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC21_3090	COG0662	Cupin 2, conserved barrel domain protein
FORC21_3091	COG2207	Transcriptional regulator
FORC21_3091	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_3095	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_3095	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_3120	COG5444	nuclease activity
FORC21_3141	COG2849	repeat protein
FORC21_3142	COG5444	nuclease activity
FORC21_3147	COG1876	peptidase activity
FORC21_3148	COG2843	Capsule synthesis protein
FORC21_3150	COG0477	Major facilitator Superfamily
FORC21_3153	COG1846	Transcriptional regulator
FORC21_3154	COG2814	Major facilitator Superfamily
FORC21_3156	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC21_3157	COG1131	(ABC) transporter
FORC21_3161	COG2031	fatty acid transporter
FORC21_3163	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_3174	COG1288	antiporter activity
FORC21_3175	COG2356	endonuclease I
FORC21_3179	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC21_3183	COG1733	regulation of RNA biosynthetic process
FORC21_3184	COG0778	Nitroreductase
FORC21_3190	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3192	COG1131	(ABC) transporter
FORC21_3197	COG1011	Hydrolase
FORC21_3204	COG0180	Tryptophanyl-tRNA synthetase
FORC21_3206	COG0628	permease
FORC21_3217	COG1253	flavin adenine dinucleotide binding
FORC21_3218	COG0789	Transcriptional regulator
FORC21_3219	COG0697	spore germination
FORC21_3221	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC21_3222	COG3813	Protein conserved in bacteria
FORC21_3223	COG2706	6-phosphogluconolactonase activity
FORC21_3224	COG1070	Carbohydrate kinase
FORC21_3227	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC21_3228	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC21_3229	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC21_3231	COG0604	alcohol dehydrogenase
FORC21_3232	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_3234	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3237	COG0840	transmembrane signaling receptor activity
FORC21_3240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_3240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_3241	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC21_3241	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC21_3242	COG1733	regulation of RNA biosynthetic process
FORC21_3245	COG0656	L-ascorbic acid biosynthetic process
FORC21_3246	COG2814	Major facilitator Superfamily
FORC21_3251	COG0814	amino acid
FORC21_3257	COG1733	regulation of RNA biosynthetic process
FORC21_3258	COG2188	Transcriptional regulator
FORC21_3259	COG0673	inositol 2-dehydrogenase activity
FORC21_3261	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC21_3262	COG1733	regulation of RNA biosynthetic process
FORC21_3263	COG1733	regulation of RNA biosynthetic process
FORC21_3267	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_3271	COG0384	phenazine biosynthesis protein PhzF
FORC21_3273	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_3274	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_3275	COG1733	regulation of RNA biosynthetic process
FORC21_3278	COG0726	polysaccharide deacetylase
FORC21_3280	COG1191	sigma factor activity
FORC21_3290	COG2801	Transposase and inactivated derivatives
FORC21_3295	COG1151	hydroxylamine reductase activity
FORC21_3301	COG2072	flavoprotein involved in K transport
FORC21_3308	COG1113	amino acid transport
FORC21_3309	COG2814	Major facilitator Superfamily
FORC21_3316	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORC21_3317	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_3320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_3321	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_3322	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_3323	COG3739	integral membrane protein
FORC21_3329	COG0583	DNA-binding transcription factor activity
FORC21_3336	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC21_3337	COG1164	Oligoendopeptidase f
FORC21_3342	COG3781	membrane
FORC21_3345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_3350	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_3352	COG0640	Transcriptional regulator
FORC21_3353	COG0604	alcohol dehydrogenase
FORC21_3355	COG0457	Tetratricopeptide repeat
FORC21_3357	COG2808	Putative FMN-binding domain
FORC21_3360	COG0277	FAD linked oxidase domain protein
FORC21_3368	COG1285	pathogenesis
FORC21_3370	COG2514	catechol 2,3-dioxygenase activity
FORC21_3372	COG2720	vancomycin resistance protein
FORC21_3378	COG1278	Cold shock
FORC21_3380	COG0716	FMN binding
FORC21_3382	COG0494	nUDIX hydrolase
FORC21_3386	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3388	COG0165	Argininosuccinate lyase
FORC21_3391	COG4145	pantothenate transmembrane transporter activity
FORC21_3393	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_3394	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3396	COG1657	PFAM Prenyltransferase squalene oxidase
FORC21_3397	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FORC21_3398	COG2962	Rard protein
FORC21_3399	COG3326	Membrane
FORC21_3402	COG0489	protein tyrosine kinase activity
FORC21_3404	COG0314	molybdopterin synthase activity
FORC21_3405	COG0303	'Molybdopterin
FORC21_3406	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_3407	COG2116	formate transmembrane transporter activity
FORC21_3409	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC21_3410	COG5609	conserved protein (DUF2294)
FORC21_3411	COG2427	Protein of unknown function (DUF1641)
FORC21_3412	COG3383	formate dehydrogenase (NAD+) activity
FORC21_3413	COG0697	spore germination
FORC21_3416	COG0531	amino acid
FORC21_3423	COG2226	methyltransferase
FORC21_3424	COG4166	transmembrane transport
FORC21_3425	COG4166	transmembrane transport
FORC21_3426	COG4166	transmembrane transport
FORC21_3427	COG1301	dicarboxylic acid transport
FORC21_3428	COG1316	TRANSCRIPTIONal
FORC21_3430	COG1595	DNA-templated transcription, initiation
FORC21_3432	COG1131	(ABC) transporter
FORC21_3440	COG0673	inositol 2-dehydrogenase activity
FORC21_3441	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC21_3442	COG0187	DNA topoisomerase II activity
FORC21_3443	COG1832	CoA-binding protein
FORC21_3444	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_3445	COG0745	RESPONSE REGULATOR receiver
FORC21_3449	COG4841	protein insertion into membrane
FORC21_3450	COG0824	Thioesterase
FORC21_3455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_3458	COG1132	(ABC) transporter
FORC21_3459	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC21_3461	COG0726	polysaccharide deacetylase
FORC21_3465	COG2211	Major facilitator Superfamily
FORC21_3467	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC21_3470	COG0183	Belongs to the thiolase family
FORC21_3471	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_3472	COG1268	BioY protein
FORC21_3473	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_3474	COG1396	sequence-specific DNA binding
FORC21_3481	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_3483	COG5002	protein histidine kinase activity
FORC21_3484	COG0400	carboxylic ester hydrolase activity
FORC21_3485	COG0346	lactoylglutathione lyase activity
FORC21_3486	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_3488	COG0069	glutamate synthase activity
FORC21_3489	COG1902	pentaerythritol trinitrate reductase activity
FORC21_3490	COG1329	Transcriptional regulator
FORC21_3491	COG0010	Belongs to the arginase family
FORC21_3501	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC21_3502	COG0785	Cytochrome C biogenesis protein
FORC21_3506	COG1131	(ABC) transporter
FORC21_3510	COG0583	DNA-binding transcription factor activity
FORC21_3512	COG1346	cytolysis
FORC21_3515	COG0730	response to heat
FORC21_3520	COG1132	(ABC) transporter
FORC21_3521	COG1132	(ABC) transporter
FORC21_3523	COG0457	Tetratricopeptide repeat
FORC21_3544	COG3639	organic phosphonate transmembrane transporter activity
FORC21_3546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_3547	COG0737	Belongs to the 5'-nucleotidase family
FORC21_3549	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC21_3553	COG1695	Transcriptional regulator
FORC21_3555	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_3555	COG1388	LysM domain
FORC21_3555	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_3556	COG0739	heme binding
FORC21_3557	COG0741	lytic transglycosylase activity
FORC21_3565	COG0174	glutamine synthetase
FORC21_3566	COG0789	Transcriptional regulator
FORC21_3567	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FORC21_3568	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC21_3569	COG2860	membrane
FORC21_3571	COG0464	growth
FORC21_3577	COG1388	LysM domain
FORC21_3577	COG3584	3D domain protein
FORC21_3578	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC21_3578	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC21_3578	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_3579	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC21_3580	COG1349	DNA-binding transcription factor activity
FORC21_3581	COG1979	alcohol dehydrogenase
FORC21_3582	COG2322	membrane
FORC21_3585	COG1113	amino acid transport
FORC21_3587	COG1408	metallophosphoesterase
FORC21_3588	COG2116	formate transmembrane transporter activity
FORC21_3591	COG2217	Heavy metal translocating P-type atpase
FORC21_3592	COG2608	mercury ion transmembrane transporter activity
FORC21_3593	COG1937	Protein conserved in bacteria
FORC21_3595	COG2819	hydrolase of the alpha beta superfamily
FORC21_3596	COG1120	ATPase activity
FORC21_3597	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_3598	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_3599	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_3600	COG0708	Exodeoxyribonuclease III
FORC21_3601	COG2169	Transcriptional regulator
FORC21_3602	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_3603	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_3607	COG2267	carboxylic ester hydrolase activity
FORC21_3608	COG3300	MHYT domain
FORC21_3608	COG5001	Diguanylate cyclase
FORC21_3612	COG1086	Polysaccharide biosynthesis protein
FORC21_3615	COG1346	cytolysis
FORC21_3617	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_3619	COG2188	Transcriptional regulator
FORC21_3620	COG2723	6-phospho-beta-galactosidase activity
FORC21_3622	COG1404	Belongs to the peptidase S8 family
FORC21_3623	COG3773	Cell wall hydrolase
FORC21_3625	COG1368	sulfuric ester hydrolase activity
FORC21_3626	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_3631	COG4550	Control of competence regulator ComK, YlbF/YmcA
FORC21_3633	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC21_3634	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC21_3634	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC21_3636	COG2359	stage V sporulation protein S
FORC21_3637	COG1692	metallophosphoesterase
FORC21_3641	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC21_3642	COG1426	Protein conserved in bacteria
FORC21_3645	COG0300	oxidoreductase activity
FORC21_3646	COG0612	Peptidase, M16
FORC21_3647	COG0612	Peptidase, M16
FORC21_3652	COG2188	Transcriptional regulator
FORC21_3655	COG0740	serine-type endopeptidase activity
FORC21_3656	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_3658	COG0527	aspartate kinase activity
FORC21_3659	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC21_3660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC21_3661	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC21_3662	COG1873	PFAM PRC-barrel domain
FORC21_3663	COG0612	Peptidase, M16
FORC21_3664	COG0726	polysaccharide deacetylase
FORC21_3667	COG0196	riboflavin kinase activity
FORC21_3670	COG1550	Protein conserved in bacteria
FORC21_3672	COG1358	cellular component organization or biogenesis
FORC21_3673	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FORC21_3674	COG0195	Participates in both transcription termination and antitermination
FORC21_3678	COG0750	zinc metalloprotease
FORC21_3680	COG4589	Belongs to the CDS family
FORC21_3689	COG4974	Belongs to the 'phage' integrase family
FORC21_3691	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC21_3692	COG0758	DNA mediated transformation
FORC21_3693	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC21_3702	COG1837	Belongs to the UPF0109 family
FORC21_3704	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC21_3706	COG0552	protein localization to endoplasmic reticulum
FORC21_3707	COG1196	nuclear chromosome segregation
FORC21_3710	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3711	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC21_3714	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC21_3715	COG1461	Dihydroxyacetone kinase
FORC21_3716	COG1302	Protein conserved in bacteria
FORC21_3718	COG1564	THIamine pyrophosphokinase
FORC21_3719	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC21_3721	COG2815	serine threonine protein kinase
FORC21_3721	COG0515	serine threonine protein kinase
FORC21_3722	COG0631	protein serine/threonine phosphatase activity
FORC21_3724	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC21_3724	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC21_3725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC21_3725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC21_3728	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC21_3729	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC21_3733	COG1561	YicC-like family, N-terminal region
FORC21_3734	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC21_3736	COG0006	proline dipeptidase activity
FORC21_3738	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC21_3751	COG0564	pseudouridine synthase activity
FORC21_3755	COG3599	regulation of cell shape
FORC21_3756	COG2302	S4 RNA-binding domain
FORC21_3757	COG0762	integral membrane protein
FORC21_3758	COG1799	cell septum assembly
FORC21_3759	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC21_3761	COG1873	PFAM PRC-barrel domain
FORC21_3762	COG1191	sigma factor activity
FORC21_3763	COG1191	sigma factor activity
FORC21_3765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC21_3766	COG0849	cell division
FORC21_3770	COG0772	Belongs to the SEDS family
FORC21_3774	COG0768	penicillin binding
FORC21_3779	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC21_3783	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC21_3785	COG3480	Lon protease (S16) C-terminal proteolytic domain
FORC21_3786	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC21_3787	COG3314	Sporulation integral membrane protein YlbJ
FORC21_3789	COG0742	ribosomal rna small subunit methyltransferase
FORC21_3792	COG3679	Belongs to the UPF0342 family
FORC21_3793	COG0406	alpha-ribazole phosphatase activity
FORC21_3796	COG2340	Cysteine-rich secretory protein family
FORC21_3799	COG3344	reverse transcriptase
FORC21_3801	COG3336	cytochrome c oxidase
FORC21_3808	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FORC21_3809	COG0772	Belongs to the SEDS family
FORC21_3811	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FORC21_3812	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC21_3814	COG4896	Protein conserved in bacteria
FORC21_3819	COG0483	inositol monophosphate 1-phosphatase activity
FORC21_3823	COG1982	Orn Lys Arg decarboxylase major
FORC21_3833	COG0022	dehydrogenase e1 component
FORC21_3834	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_3837	COG0561	phosphatase activity
FORC21_3839	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_3840	COG0569	domain protein
FORC21_3844	COG0583	DNA-binding transcription factor activity
FORC21_3845	COG0517	IMP dehydrogenase activity
FORC21_3847	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FORC21_3849	COG4703	Protein of unknown function (DUF1797)
FORC21_3852	COG2200	EAL domain
FORC21_3853	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3854	COG1408	metallophosphoesterase
FORC21_3863	COG2814	Major facilitator Superfamily
FORC21_3867	COG3209	COG3209 Rhs family protein
FORC21_3869	COG2205	protein histidine kinase activity
FORC21_3871	COG0436	Aminotransferase
FORC21_3872	COG1609	Transcriptional regulator
FORC21_3873	COG3833	ABC-type maltose transport systems, permease component
FORC21_3874	COG1175	transmembrane transport
FORC21_3875	COG2182	Extracellular solute-binding protein
FORC21_3877	COG0366	Alpha amylase catalytic
FORC21_3878	COG3842	ATPase activity
FORC21_3886	COG0183	Belongs to the thiolase family
FORC21_3892	COG1695	Transcriptional regulator
FORC21_3893	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_3897	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC21_3898	COG0436	Aminotransferase
FORC21_3905	COG2084	Dehydrogenase
FORC21_3907	COG2203	Gaf domain
FORC21_3907	COG2199	diguanylate cyclase activity
FORC21_3908	COG0778	Nitroreductase
FORC21_3913	COG1263	PTS System
FORC21_3913	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_3913	COG2190	(PTS) system
FORC21_3914	COG3711	transcriptional antiterminator
FORC21_3918	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC21_3923	COG1547	Domain of unknown function (DUF309)
FORC21_3924	COG0456	acetyltransferase
FORC21_3925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC21_3926	COG4086	secreted protein
FORC21_3927	COG0561	phosphatase activity
FORC21_3928	COG0697	spore germination
FORC21_3931	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC21_3936	COG0733	neurotransmitter:sodium symporter activity
FORC21_3940	COG1686	Belongs to the peptidase S11 family
FORC21_3941	COG1725	Transcriptional regulator
FORC21_3942	COG1131	(ABC) transporter
FORC21_3946	COG1846	Transcriptional regulator
FORC21_3949	COG0598	Magnesium transport protein CorA
FORC21_3954	COG4974	Belongs to the 'phage' integrase family
FORC21_3956	COG0735	belongs to the Fur family
FORC21_3957	COG1300	Membrane
FORC21_3961	COG0667	Aldo Keto reductase
FORC21_3962	COG0656	L-ascorbic acid biosynthetic process
FORC21_3963	COG0456	acetyltransferase
FORC21_3963	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC21_3965	COG1525	nuclease
FORC21_3965	COG4085	toxin activity
FORC21_3965	COG0737	Belongs to the 5'-nucleotidase family
FORC21_3967	COG0596	Alpha beta hydrolase
FORC21_3968	COG2056	Na+-H+ antiporter family
FORC21_3969	COG1609	Transcriptional regulator
FORC21_3970	COG0456	acetyltransferase
FORC21_3971	COG1073	alpha beta
FORC21_3974	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_3974	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_3975	COG0307	riboflavin synthase, alpha
FORC21_3981	COG2226	methyltransferase
FORC21_3981	COG1073	alpha beta
FORC21_3984	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_3987	COG0737	Belongs to the 5'-nucleotidase family
FORC21_3989	COG1522	sequence-specific DNA binding
FORC21_3998	COG0300	oxidoreductase activity
FORC21_3999	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_4000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_4001	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_4002	COG1760	l-serine dehydratase
FORC21_4003	COG1760	l-serine dehydratase
FORC21_4010	COG1285	pathogenesis
FORC21_4012	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC21_4013	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_4015	COG1376	ErfK ybiS ycfS ynhG family protein
FORC21_4016	COG4129	membrane
FORC21_4017	COG1126	abc transporter atp-binding protein
FORC21_4018	COG0765	amino acid transport
FORC21_4019	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_4023	COG2323	membrane
FORC21_4024	COG0772	Belongs to the SEDS family
FORC21_4025	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_4026	COG0022	dehydrogenase e1 component
FORC21_4027	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_4028	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_4030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC21_4031	COG0280	phosphate acetyltransferase
FORC21_4032	COG3829	transcription factor binding
FORC21_4032	COG3290	protein histidine kinase activity
FORC21_4034	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_4035	COG3093	addiction module antidote protein HigA
FORC21_4038	COG0750	zinc metalloprotease
FORC21_4039	COG0497	DNA recombination
FORC21_4041	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FORC21_4043	COG0142	geranyltranstransferase activity
FORC21_4048	COG1302	Protein conserved in bacteria
FORC21_4049	COG0439	Biotin carboxylase
FORC21_4050	COG0511	ligase activity, forming carbon-carbon bonds
FORC21_4058	COG3854	ATPases associated with a variety of cellular activities
FORC21_4063	COG0006	proline dipeptidase activity
FORC21_4067	COG3872	metal-dependent enzyme
FORC21_4069	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC21_4076	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_4078	COG1609	Transcriptional regulator
FORC21_4080	COG2076	Multidrug Resistance protein
FORC21_4081	COG2076	Multidrug Resistance protein
FORC21_4088	COG1131	(ABC) transporter
FORC21_4089	COG1725	Transcriptional regulator
FORC21_4095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_4102	COG2169	Transcriptional regulator
FORC21_4103	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_4109	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_4110	COG2169	Transcriptional regulator
FORC21_4115	COG2264	protein methyltransferase activity
FORC21_4126	COG1459	type II secretion system
FORC21_4127	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC21_4138	COG1410	methionine synthase
FORC21_4138	COG0646	methionine synthase
FORC21_4139	COG0646	methionine synthase
FORC21_4139	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC21_4140	COG0626	cystathionine gamma-synthase activity
FORC21_4141	COG0626	cystathionine gamma-synthase activity
FORC21_4145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_4147	COG1940	carbohydrate kinase activity
FORC21_4148	COG4483	Protein conserved in bacteria
FORC21_4149	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC21_4151	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC21_4152	COG0704	Plays a role in the regulation of phosphate uptake
FORC21_4154	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_4155	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_4156	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC21_4158	COG0477	Major facilitator Superfamily
FORC21_4159	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC21_4160	COG5521	maltodextrose utilization protein MalA
FORC21_4163	COG0735	belongs to the Fur family
FORC21_4164	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC21_4165	COG1121	(ABC) transporter
FORC21_4166	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_4172	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC21_4173	COG2384	SAM-dependent methyltransferase
FORC21_4175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC21_4176	COG0358	DNA primase activity
FORC21_4177	COG1671	Belongs to the UPF0178 family
FORC21_4179	COG0517	IMP dehydrogenase activity
FORC21_4182	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC21_4183	COG0295	cytidine deaminase activity
FORC21_4184	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC21_4186	COG1480	7TM receptor with intracellular HD hydrolase
FORC21_4187	COG1702	phosphate starvation-inducible protein PhoH
FORC21_4190	COG1610	YqeY-like protein
FORC21_4192	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC21_4193	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC21_4199	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC21_4200	COG1733	regulation of RNA biosynthetic process
FORC21_4205	COG1466	dna polymerase III delta subunit
FORC21_4207	COG0658	competence protein
FORC21_4207	COG2333	competence protein COMEC
FORC21_4208	COG2131	deaminase
FORC21_4209	COG1596	polysaccharide export
FORC21_4209	COG1555	photosystem II stabilization
FORC21_4210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_4211	COG2226	methyltransferase
FORC21_4212	COG0799	negative regulation of ribosome biogenesis
FORC21_4213	COG1713	HD superfamily hydrolase involved in NAD metabolism
FORC21_4215	COG1534	Rna-binding protein
FORC21_4217	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC21_4218	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FORC21_4221	COG1191	sigma factor activity
FORC21_4225	COG0778	Nitroreductase
FORC21_4226	COG2357	RelA SpoT domain protein
FORC21_4228	COG1785	Belongs to the alkaline phosphatase family
FORC21_4230	COG2267	carboxylic ester hydrolase activity
FORC21_4237	COG1404	Belongs to the peptidase S8 family
FORC21_4238	COG3186	Phenylalanine-4-hydroxylase
FORC21_4240	COG2514	catechol 2,3-dioxygenase activity
FORC21_4241	COG2259	Doxx family
FORC21_4249	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_4251	COG1454	alcohol dehydrogenase
FORC21_4251	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_4252	COG0626	cystathionine gamma-synthase activity
FORC21_4253	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_4258	COG0768	penicillin binding
FORC21_4265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC21_4271	COG0628	permease
FORC21_4275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC21_4278	COG1104	cysteine desulfurase activity
FORC21_4279	COG1959	2 iron, 2 sulfur cluster binding
FORC21_4280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC21_4282	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC21_4287	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC21_4289	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC21_4289	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORC21_4290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC21_4291	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC21_4291	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC21_4293	COG2244	polysaccharide biosynthetic process
FORC21_4294	COG2323	membrane
FORC21_4296	COG1862	Preprotein translocase
FORC21_4302	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC21_4308	COG0157	Belongs to the NadC ModD family
FORC21_4309	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC21_4310	COG1104	cysteine desulfurase activity
FORC21_4311	COG1827	regulation of RNA biosynthetic process
FORC21_4312	COG2258	MOSC domain
FORC21_4313	COG0077	Prephenate dehydratase
FORC21_4314	COG0577	efflux transmembrane transporter activity
FORC21_4315	COG0577	efflux transmembrane transporter activity
FORC21_4316	COG1136	(ABC) transporter
FORC21_4317	COG5002	protein histidine kinase activity
FORC21_4318	COG0745	RESPONSE REGULATOR receiver
FORC21_4320	COG3290	protein histidine kinase activity
FORC21_4322	COG2868	ribosomal protein
FORC21_4324	COG1530	ribonuclease E activity
FORC21_4325	COG1994	Peptidase M50
FORC21_4326	COG0739	heme binding
FORC21_4327	COG2894	cell division
FORC21_4330	COG1792	Involved in formation and maintenance of cell shape
FORC21_4331	COG1077	Cell shape determining protein MreB Mrl
FORC21_4335	COG0285	dihydrofolate synthase activity
FORC21_4338	COG1388	LysM domain
FORC21_4340	COG0113	porphobilinogen synthase activity
FORC21_4341	COG1587	Uroporphyrinogen-III synthase
FORC21_4343	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC21_4345	COG1846	Transcriptional regulator
FORC21_4346	COG1764	response to oxidative stress
FORC21_4352	COG0470	DNA polymerase III
FORC21_4352	COG1067	ATP-dependent peptidase activity
FORC21_4360	COG0622	Phosphoesterase
FORC21_4363	COG5401	PFAM Sporulation and spore germination
FORC21_4367	COG1309	transcriptional regulator
FORC21_4397	COG3621	Patatin-like phospholipase
FORC21_4401	COG2197	response regulator
FORC21_4402	COG2233	PERMEase
FORC21_4403	COG0402	S-adenosylhomocysteine deaminase activity
FORC21_4404	COG1983	PspC domain protein
FORC21_4405	COG1396	sequence-specific DNA binding
FORC21_4406	COG0697	spore germination
FORC21_4408	COG1959	2 iron, 2 sulfur cluster binding
FORC21_4409	COG1668	transmembrane transport
FORC21_4410	COG4152	abc transporter atp-binding protein
FORC21_4411	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FORC21_4412	COG1360	Flagellar Motor Protein
FORC21_4413	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC21_4414	COG1876	peptidase activity
FORC21_4415	COG0824	Thioesterase
FORC21_4416	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC21_4417	COG1053	succinate dehydrogenase
FORC21_4418	COG2009	succinate dehydrogenase
FORC21_4419	COG1719	4-vinyl reductase, 4VR
FORC21_4421	COG3118	belongs to the thioredoxin family
FORC21_4422	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORC21_4423	COG2086	electron transfer activity
FORC21_4424	COG1024	Enoyl-CoA hydratase
FORC21_4425	COG1309	transcriptional regulator
FORC21_4426	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_4431	COG2318	DinB family
FORC21_4436	COG1131	(ABC) transporter
FORC21_4437	COG2205	protein histidine kinase activity
FORC21_4438	COG0745	RESPONSE REGULATOR receiver
FORC21_4440	COG4895	conserved protein (DUF2196)
FORC21_4441	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC21_4443	COG4509	Sortase family
FORC21_4444	COG1120	ATPase activity
FORC21_4447	COG5386	Cell surface protein
FORC21_4449	COG5386	Cell surface protein
FORC21_4450	COG1114	Component of the transport system for branched-chain amino acids
FORC21_4451	COG1187	pseudouridine synthase activity
FORC21_4454	COG1796	DNA polymerase
FORC21_4454	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC21_4455	COG1286	toxin biosynthetic process
FORC21_4463	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC21_4465	COG1418	mRNA catabolic process
FORC21_4466	COG2814	Major facilitator Superfamily
FORC21_4467	COG1566	PFAM secretion protein HlyD family protein
FORC21_4468	COG1309	transcriptional regulator
FORC21_4469	COG1363	Peptidase, m42
FORC21_4474	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC21_4477	COG1484	DNA-dependent DNA replication
FORC21_4478	COG3611	Membrane attachment protein
FORC21_4480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC21_4481	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC21_4483	COG1971	Probably functions as a manganese efflux pump
FORC21_4485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_4485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_4486	COG5002	protein histidine kinase activity
FORC21_4487	COG0745	RESPONSE REGULATOR receiver
FORC21_4492	COG0538	isocitrate dehydrogenase activity
FORC21_4493	COG0372	Belongs to the citrate synthase family
FORC21_4495	COG0628	permease
FORC21_4496	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC21_4501	COG1725	Transcriptional regulator
FORC21_4502	COG0281	malic enzyme
FORC21_4503	COG0587	DNA-directed DNA polymerase activity
FORC21_4506	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC21_4509	COG4109	DRTGG domain
FORC21_4512	COG0006	proline dipeptidase activity
FORC21_4518	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_4519	COG0662	Cupin 2, conserved barrel domain protein
FORC21_4522	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_4523	COG0589	response to stress
FORC21_4532	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_4537	COG0827	DNA restriction-modification system
FORC21_4538	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC21_4541	COG3874	Sporulation protein YtfJ
FORC21_4544	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FORC21_4546	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_4549	COG1104	cysteine desulfurase activity
FORC21_4551	COG0583	DNA-binding transcription factor activity
FORC21_4552	COG0697	spore germination
FORC21_4553	COG1309	transcriptional regulator
FORC21_4554	COG1956	GAF domain-containing protein
FORC21_4555	COG0626	cystathionine gamma-synthase activity
FORC21_4562	COG0110	maltose O-acetyltransferase activity
FORC21_4563	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_4564	COG0454	-acetyltransferase
FORC21_4565	COG0517	IMP dehydrogenase activity
FORC21_4566	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC21_4569	COG0745	RESPONSE REGULATOR receiver
FORC21_4571	COG0666	response to abiotic stimulus
FORC21_4578	COG1609	Transcriptional regulator
FORC21_4579	COG1605	Chorismate mutase
FORC21_4579	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC21_4580	COG4851	CamS sex pheromone cAM373 precursor
FORC21_4581	COG3118	belongs to the thioredoxin family
FORC21_4583	COG2309	aminopeptidase activity
FORC21_4588	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_4591	COG1674	ftsk spoiiie
FORC21_4592	COG1388	LysM domain
FORC21_4592	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_4594	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC21_4596	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_4597	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC21_4598	COG1363	Peptidase, m42
FORC21_4600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_4603	COG0510	thiamine kinase activity
FORC21_4604	COG1523	belongs to the glycosyl hydrolase 13 family
FORC21_4606	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_4607	COG1349	DNA-binding transcription factor activity
FORC21_4608	COG1187	pseudouridine synthase activity
FORC21_4609	COG2244	polysaccharide biosynthetic process
FORC21_4610	COG2081	HI0933 family
FORC21_4611	COG2814	Major facilitator Superfamily
FORC21_4613	COG3832	glyoxalase III activity
FORC21_4617	COG1329	Transcriptional regulator
FORC21_4622	COG0314	molybdopterin synthase activity
FORC21_4623	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC21_4624	COG0303	'Molybdopterin
FORC21_4626	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_4627	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC21_4631	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_4633	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC21_4641	COG2814	Major facilitator Superfamily
FORC21_4642	COG0475	glutathione-regulated potassium exporter activity
FORC21_4643	COG0490	domain, Protein
FORC21_4644	COG0582	viral genome integration into host DNA
FORC21_4646	COG1136	(ABC) transporter
FORC21_4650	COG1242	4 iron, 4 sulfur cluster binding
FORC21_4651	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FORC21_4654	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_4657	COG2267	carboxylic ester hydrolase activity
FORC21_4658	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC21_4659	COG0671	phosphoesterase, PA-phosphatase related
FORC21_4660	COG0438	transferase activity, transferring glycosyl groups
FORC21_4664	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_4673	COG5002	protein histidine kinase activity
FORC21_4674	COG3852	Histidine kinase
FORC21_4677	COG2267	carboxylic ester hydrolase activity
FORC21_4678	COG1368	sulfuric ester hydrolase activity
FORC21_4681	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_4682	COG1116	anion transmembrane transporter activity
FORC21_4683	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_4689	COG0494	nUDIX hydrolase
FORC21_4697	COG0288	reversible hydration of carbon dioxide
FORC21_4698	COG1271	oxidase subunit
FORC21_4699	COG1294	oxidase, subunit
FORC21_4702	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_4706	COG1842	Phage shock protein A
FORC21_4712	COG5002	protein histidine kinase activity
FORC21_4713	COG0745	RESPONSE REGULATOR receiver
FORC21_4719	COG1597	lipid kinase activity
FORC21_4727	COG0577	efflux transmembrane transporter activity
FORC21_4728	COG1136	(ABC) transporter
FORC21_4731	COG0586	Pfam SNARE associated Golgi protein
FORC21_4733	COG0577	efflux transmembrane transporter activity
FORC21_4734	COG1136	(ABC) transporter
FORC21_4735	COG2207	Transcriptional regulator
FORC21_4735	COG3708	Transcriptional regulator
FORC21_4736	COG5658	integral membrane protein
FORC21_4737	COG0640	Transcriptional regulator
FORC21_4738	COG0745	RESPONSE REGULATOR receiver
FORC21_4739	COG2205	protein histidine kinase activity
FORC21_4740	COG0577	efflux transmembrane transporter activity
FORC21_4741	COG0577	efflux transmembrane transporter activity
FORC21_4742	COG1136	(ABC) transporter
FORC21_4743	COG0577	efflux transmembrane transporter activity
FORC21_4752	COG3964	amidohydrolase
FORC21_4756	COG4948	Mandelate Racemase Muconate Lactonizing
FORC21_4758	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC21_4759	COG0596	Alpha beta hydrolase
FORC21_4761	COG1169	isochorismate synthase
FORC21_4762	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC21_4763	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC21_4764	COG1278	Cold shock
FORC21_4769	COG0058	SHG alpha-glucan phosphorylase activity
FORC21_4771	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC21_4775	COG1404	Belongs to the peptidase S8 family
FORC21_4777	COG1285	pathogenesis
FORC21_4778	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC21_4781	COG2155	Conserved Protein
FORC21_4782	COG1098	S1 RNA binding domain
FORC21_4783	COG0436	Aminotransferase
FORC21_4784	COG1522	sequence-specific DNA binding
FORC21_4785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC21_4786	COG2267	carboxylic ester hydrolase activity
FORC21_4788	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC21_4792	COG5018	Exonuclease
FORC21_4793	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_4796	COG0423	glycine-tRNA ligase activity
FORC21_4797	COG2050	protein possibly involved in aromatic compounds catabolism
FORC21_4799	COG1268	BioY protein
FORC21_4800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC21_4801	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC21_4805	COG2076	Multidrug Resistance protein
FORC21_4806	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC21_4808	COG3584	3D domain protein
FORC21_4811	COG1252	NADH dehydrogenase
FORC21_4814	COG3708	Transcriptional regulator
FORC21_4817	COG1683	Conserved Protein
FORC21_4822	COG0316	Belongs to the HesB IscA family
FORC21_4825	COG1252	NADH dehydrogenase
FORC21_4827	COG0390	transport system, permease component
FORC21_4828	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC21_4836	COG4837	Protein of unknown function (DUF1462)
FORC21_4837	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC21_4839	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC21_4840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC21_4842	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_4844	COG0647	UMP catabolic process
FORC21_4846	COG2445	Protein of unknown function DUF86
FORC21_4847	COG1494	fructose-1,6-bisphosphatase
FORC21_4851	COG4470	Protein conserved in bacteria
FORC21_4853	COG0789	Transcriptional regulator
FORC21_4854	COG4377	Putative membrane peptidase family (DUF2324)
FORC21_4859	COG0739	heme binding
FORC21_4861	COG3377	Domain of unknown function (DUF1805)
FORC21_4862	COG0737	Belongs to the 5'-nucleotidase family
FORC21_4863	COG0719	Fe-S assembly protein
FORC21_4864	COG0822	iron-sulfur transferase activity
FORC21_4865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC21_4866	COG0719	Fe-S assembly protein
FORC21_4867	COG0396	ATPase activity
FORC21_4868	COG1464	Belongs to the NlpA lipoprotein family
FORC21_4869	COG1464	Belongs to the NlpA lipoprotein family
FORC21_4870	COG2011	ABC-type metal ion transport system permease component
FORC21_4871	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC21_4873	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_4874	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FORC21_4876	COG1393	Belongs to the ArsC family
FORC21_4877	COG1393	Belongs to the ArsC family
FORC21_4885	COG1309	transcriptional regulator
FORC21_4886	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_4887	COG1960	acyl-CoA dehydrogenase activity
FORC21_4888	COG0183	Belongs to the thiolase family
FORC21_4889	COG1024	Enoyl-CoA hydratase
FORC21_4889	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC21_4891	COG1686	Belongs to the peptidase S11 family
FORC21_4894	COG0011	TIGRFAM Protein of
FORC21_4895	COG0840	transmembrane signaling receptor activity
FORC21_4898	COG2814	Major facilitator Superfamily
FORC21_4899	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FORC21_4901	COG0531	amino acid
FORC21_4907	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_4915	COG0586	Pfam SNARE associated Golgi protein
FORC21_4917	COG1376	ErfK ybiS ycfS ynhG family protein
FORC21_4918	COG0745	RESPONSE REGULATOR receiver
FORC21_4919	COG5002	protein histidine kinase activity
FORC21_4927	COG0840	transmembrane signaling receptor activity
FORC21_4928	COG2151	metal-sulfur cluster biosynthetic enzyme
FORC21_4929	COG3227	Zinc metalloprotease (Elastase)
FORC21_4930	COG1741	Belongs to the pirin family
FORC21_4933	COG0586	Pfam SNARE associated Golgi protein
FORC21_4934	COG0475	glutathione-regulated potassium exporter activity
FORC21_4935	COG0490	domain, Protein
FORC21_4936	COG1115	amino acid carrier protein
FORC21_4937	COG0783	Belongs to the Dps family
FORC21_4940	COG1611	Belongs to the LOG family
FORC21_4942	COG1528	Iron-storage protein
FORC21_4944	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_4945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_4946	COG1115	amino acid carrier protein
FORC21_4947	COG1115	amino acid carrier protein
FORC21_4948	COG2910	NAD(P)H-binding
FORC21_4951	COG0656	L-ascorbic acid biosynthetic process
FORC21_4952	COG2814	Major facilitator Superfamily
FORC21_4953	COG1733	regulation of RNA biosynthetic process
FORC21_4955	COG1252	NADH dehydrogenase
FORC21_4956	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC21_4966	COG0488	(ABC) transporter
FORC21_4967	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_4969	COG3223	Belongs to the PsiE family
FORC21_4981	COG0557	exoribonuclease II activity
FORC21_4982	COG1647	Serine aminopeptidase, S33
FORC21_4983	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC21_4984	COG1346	cytolysis
FORC21_4991	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC21_4994	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC21_4996	COG1668	transmembrane transport
FORC21_4997	COG4152	abc transporter atp-binding protein
FORC21_4998	COG4585	Histidine kinase
FORC21_5003	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC21_5006	COG2323	membrane
FORC21_5008	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_5010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC21_5012	COG1051	belongs to the nudix hydrolase family
FORC21_5014	COG0492	ferredoxin-NADP+ reductase activity
FORC21_5015	COG0457	Tetratricopeptide repeat
FORC21_5016	COG0110	maltose O-acetyltransferase activity
FORC21_5020	COG1950	PFAM Membrane protein of
FORC21_5021	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC21_5022	COG0556	nucleotide-excision repair
FORC21_5025	COG0789	Transcriptional regulator
FORC21_5029	COG0583	DNA-binding transcription factor activity
FORC21_5031	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC21_5034	COG1132	(ABC) transporter
FORC21_5035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_5036	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_5036	COG0793	Belongs to the peptidase S41A family
FORC21_5037	COG2177	Part of the ABC transporter FtsEX involved in
FORC21_5038	COG2884	Cell division ATP-binding protein ftsE
FORC21_5040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC21_5043	COG1131	(ABC) transporter
FORC21_5049	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC21_5050	COG1278	Cold shock
FORC21_5051	COG1040	competence protein
FORC21_5052	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FORC21_5053	COG0791	NLP P60 protein
FORC21_5054	COG1733	regulation of RNA biosynthetic process
FORC21_5055	COG1307	EDD domain protein, DegV family
FORC21_5056	COG1739	Uncharacterized protein family UPF0029
FORC21_5057	COG1316	TRANSCRIPTIONal
FORC21_5058	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC21_5059	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC21_5060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC21_5062	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC21_5062	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FORC21_5066	COG1486	melibiose metabolic process
FORC21_5067	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_5068	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_5072	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_5074	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_5075	COG1301	dicarboxylic acid transport
FORC21_5081	COG1511	domain protein
FORC21_5082	COG0583	DNA-binding transcription factor activity
FORC21_5083	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC21_5085	COG1271	oxidase subunit
FORC21_5086	COG1294	oxidase, subunit
FORC21_5087	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_5089	COG1620	l-lactate permease
FORC21_5091	COG2389	metal-binding protein
FORC21_5093	COG1368	sulfuric ester hydrolase activity
FORC21_5095	COG0791	NLP P60 protein
FORC21_5095	COG1388	LysM domain
FORC21_5097	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_5099	COG1215	transferase activity, transferring glycosyl groups
FORC21_5101	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_5102	COG1388	LysM domain
FORC21_5102	COG3584	3D domain protein
FORC21_5107	COG4715	Zinc finger, swim domain protein
FORC21_5108	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_5114	COG1191	sigma factor activity
FORC21_5116	COG0577	efflux transmembrane transporter activity
FORC21_5117	COG1136	(ABC) transporter
FORC21_5122	COG5002	protein histidine kinase activity
FORC21_5123	COG0745	RESPONSE REGULATOR receiver
FORC21_5124	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC21_5127	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC21_5130	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC21_5131	COG0438	transferase activity, transferring glycosyl groups
FORC21_5133	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FORC21_5134	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC21_5137	COG1215	transferase activity, transferring glycosyl groups
FORC21_5138	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC21_5139	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC21_5140	COG4464	protein tyrosine phosphatase activity
FORC21_5141	COG0489	protein tyrosine kinase activity
FORC21_5142	COG3944	biosynthesis protein
FORC21_5143	COG0489	protein tyrosine kinase activity
FORC21_5146	COG1609	Transcriptional regulator
FORC21_5148	COG0739	heme binding
FORC21_5151	COG4555	ABC transporter
FORC21_5152	COG2385	sporulation resulting in formation of a cellular spore
FORC21_5155	COG4836	Membrane
FORC21_5156	COG1007	ATP synthesis coupled electron transport
FORC21_5157	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC21_5158	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC21_5160	COG0839	Belongs to the complex I subunit 6 family
FORC21_5164	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC21_5167	COG3300	MHYT domain
FORC21_5167	COG5001	Diguanylate cyclase
FORC21_5177	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC21_5184	COG0698	ribose 5-phosphate isomerase
FORC21_5187	COG2259	Doxx family
FORC21_5188	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC21_5192	COG0009	L-threonylcarbamoyladenylate synthase
FORC21_5199	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC21_5200	COG1494	fructose-1,6-bisphosphatase
FORC21_5204	COG4821	SIS domain
FORC21_5208	COG1960	acyl-CoA dehydrogenase activity
FORC21_5209	COG1960	acyl-CoA dehydrogenase activity
FORC21_5210	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC21_5211	COG0183	Belongs to the thiolase family
FORC21_5212	COG0247	lactate metabolic process
FORC21_5212	COG2181	nitrate reductase activity
FORC21_5213	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_5215	COG3300	MHYT domain
FORC21_5215	COG5001	Diguanylate cyclase
FORC21_5218	COG3227	Zinc metalloprotease (Elastase)
FORC21_5219	COG2197	response regulator
FORC21_5220	COG4585	Histidine kinase
FORC21_5221	COG0842	Transport permease protein
FORC21_5222	COG1131	(ABC) transporter
FORC21_5223	COG0024	Methionine aminopeptidase
FORC21_5225	COG2234	aminopeptidase activity
FORC21_5229	COG1595	DNA-templated transcription, initiation
FORC21_5231	COG4506	Protein conserved in bacteria
FORC21_5232	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_5236	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC21_5237	COG2814	Major facilitator Superfamily
FORC21_5238	COG0789	Transcriptional regulator
FORC21_5239	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_5240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_5242	COG1994	Peptidase M50
FORC21_5244	COG1078	dGTPase activity
FORC21_5245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_5246	COG1120	ATPase activity
FORC21_5247	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_5248	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_5252	COG0280	phosphate acetyltransferase
FORC21_5255	COG3773	Cell wall hydrolase
FORC21_5257	COG2363	Small membrane protein
FORC21_5259	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC21_5260	COG2233	PERMEase
FORC21_5261	COG0561	phosphatase activity
FORC21_5262	COG2814	Major facilitator Superfamily
FORC21_5264	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC21_5265	COG1131	(ABC) transporter
FORC21_5266	COG2755	lipolytic protein G-D-S-L family
FORC21_5267	COG1609	Transcriptional regulator
FORC21_5269	COG0460	homoserine dehydrogenase
FORC21_5273	COG1011	Hydrolase
FORC21_5274	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_5276	COG2197	response regulator
FORC21_5277	COG2197	response regulator
FORC21_5278	COG4585	Histidine kinase
FORC21_5278	COG2203	Gaf domain
FORC21_5279	COG0351	phosphomethylpyrimidine kinase
FORC21_5280	COG3706	GGDEF domain
FORC21_5281	COG2879	small protein
FORC21_5282	COG1966	Carbon starvation protein
FORC21_5283	COG3279	Response regulator of the LytR AlgR family
FORC21_5284	COG0477	Major facilitator Superfamily
FORC21_5286	COG0438	transferase activity, transferring glycosyl groups
FORC21_5289	COG0840	transmembrane signaling receptor activity
FORC21_5291	COG1607	acyl-coa hydrolase
FORC21_5292	COG1216	Glycosyl transferase, family 2
FORC21_5294	COG1216	Glycosyl transferase, family 2
FORC21_5296	COG4485	Bacterial membrane protein, YfhO
FORC21_5297	COG0463	Glycosyl transferase, family 2
FORC21_5298	COG0488	(ABC) transporter
FORC21_5299	COG1309	transcriptional regulator
FORC21_5300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC21_5301	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_5301	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_5302	COG0628	permease
FORC21_5306	COG3275	phosphorelay sensor kinase activity
FORC21_5307	COG2814	Major facilitator Superfamily
FORC21_5308	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_5309	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FORC21_5313	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC21_5314	COG1272	protein, Hemolysin III
FORC21_5318	COG1164	Oligoendopeptidase f
FORC21_5320	COG5002	protein histidine kinase activity
FORC21_5323	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_5324	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC21_5325	COG4853	Protein conserved in bacteria
FORC21_5327	COG5002	protein histidine kinase activity
FORC21_5328	COG0745	RESPONSE REGULATOR receiver
FORC21_5330	COG0305	Participates in initiation and elongation during chromosome replication
FORC21_5332	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FORC21_5333	COG4241	membrane
FORC21_5337	COG0012	GTP binding
FORC21_5338	COG4481	Protein conserved in bacteria
FORC21_5339	COG0668	transmembrane transport
FORC21_5341	COG1475	DNA binding
FORC21_5342	COG1192	Involved in chromosome partitioning
FORC21_5347	COG1847	R3H domain protein
FORC21_5352	COG1396	sequence-specific DNA binding
FORC21_5355	COG1396	sequence-specific DNA binding
FORC21_5359	COG0419	ATPase involved in DNA repair
FORC21_5363	COG1484	DNA-dependent DNA replication
FORC21_5380	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FORC21_5388	COG5484	DNA packaging
FORC21_t099	COG0544	peptidyl-prolyl cis-trans isomerase activity