locus-tag	class	description
FORC48_0002	COG0592	DNA-directed DNA polymerase activity
FORC48_0003	COG2501	S4 domain
FORC48_0005	COG0187	DNA topoisomerase II activity
FORC48_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC48_0008	COG0517	IMP dehydrogenase activity
FORC48_0008	COG0516	GMP reductase activity
FORC48_0009	COG1686	Belongs to the peptidase S11 family
FORC48_0014	COG1428	Deoxynucleoside kinase
FORC48_0015	COG1428	Deoxynucleoside kinase
FORC48_0016	COG1335	isochorismatase
FORC48_0017	COG0590	tRNA wobble adenosine to inosine editing
FORC48_0018	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC48_0024	COG1982	Orn Lys Arg decarboxylase major
FORC48_0026	COG0470	DNA polymerase III
FORC48_0027	COG1774	PSP1 C-terminal conserved region
FORC48_0029	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC48_0031	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC48_0032	COG2002	toxin-antitoxin pair type II binding
FORC48_0034	COG0084	hydrolase, TatD family'
FORC48_0038	COG4466	Protein conserved in bacteria
FORC48_0041	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC48_0042	COG0251	oxidation-reduction process
FORC48_0045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC48_0048	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC48_0049	COG2002	toxin-antitoxin pair type II binding
FORC48_0050	COG2244	polysaccharide biosynthetic process
FORC48_0051	COG3956	TIGRFAM MazG family protein
FORC48_0052	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC48_0056	COG1098	S1 RNA binding domain
FORC48_0057	COG2208	phosphoserine phosphatase activity
FORC48_0060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC48_0063	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_0065	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC48_0066	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_0067	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC48_0068	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC48_0069	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC48_0070	COG1396	sequence-specific DNA binding
FORC48_0071	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC48_0075	COG3880	PFAM UvrB UvrC protein
FORC48_0077	COG0542	response to heat
FORC48_0078	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC48_0080	COG4956	integral membrane protein (PIN domain superfamily)
FORC48_0084	COG1045	serine acetyltransferase
FORC48_0087	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC48_0088	COG3688	RNA-binding protein containing a PIN domain
FORC48_0090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC48_0091	COG0250	Participates in transcription elongation, termination and antitermination
FORC48_0096	COG2813	Specifically methylates the guanine in position
FORC48_0099	COG1358	cellular component organization or biogenesis
FORC48_0120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC48_0125	COG0201	protein transport
FORC48_0127	COG0024	Methionine aminopeptidase
FORC48_0129	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC48_0136	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FORC48_0141	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_0142	COG0489	protein tyrosine kinase activity
FORC48_0144	COG2194	sulfuric ester hydrolase activity
FORC48_0145	COG0726	polysaccharide deacetylase
FORC48_0149	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORC48_0150	COG4856	YbbR-like protein
FORC48_0160	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_0161	COG2011	ABC-type metal ion transport system permease component
FORC48_0162	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC48_0163	COG1464	Belongs to the NlpA lipoprotein family
FORC48_0165	COG0604	alcohol dehydrogenase
FORC48_0167	COG0277	FAD linked oxidase domain protein
FORC48_0168	COG2271	Major facilitator Superfamily
FORC48_0170	COG2814	Major facilitator Superfamily
FORC48_0173	COG0601	transmembrane transport
FORC48_0174	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_0175	COG0444	Belongs to the ABC transporter superfamily
FORC48_0176	COG4608	Belongs to the ABC transporter superfamily
FORC48_0177	COG4166	transmembrane transport
FORC48_0179	COG2207	Transcriptional regulator
FORC48_0182	COG4166	transmembrane transport
FORC48_0183	COG4166	transmembrane transport
FORC48_0184	COG0656	L-ascorbic acid biosynthetic process
FORC48_0187	COG4149	molybdate abc transporter
FORC48_0188	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC48_0189	COG1910	domain protein
FORC48_0193	COG0697	spore germination
FORC48_0197	COG0204	Acyl-transferase
FORC48_0200	COG1609	Transcriptional regulator
FORC48_0202	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_0206	COG5298	Protein conserved in bacteria
FORC48_0211	COG0488	(ABC) transporter
FORC48_0213	COG0747	negative chemotaxis
FORC48_0214	COG0601	transmembrane transport
FORC48_0216	COG0444	Belongs to the ABC transporter superfamily
FORC48_0217	COG4608	Belongs to the ABC transporter superfamily
FORC48_0218	COG0561	phosphatase activity
FORC48_0224	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORC48_0225	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC48_0227	COG0531	amino acid
FORC48_0228	COG2814	Major facilitator Superfamily
FORC48_0230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC48_0232	COG4294	response to UV
FORC48_0233	COG0705	Rhomboid family
FORC48_0235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC48_0236	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC48_0237	COG0864	Transcriptional regulator
FORC48_0238	COG2337	Toxic component of a toxin-antitoxin (TA) module
FORC48_0239	COG2183	response to ionizing radiation
FORC48_0242	COG0802	atpase or kinase
FORC48_0243	COG1214	PFAM Peptidase M22, glycoprotease
FORC48_0244	COG0456	acetyltransferase
FORC48_0246	COG0488	(ABC) transporter
FORC48_0249	COG1266	CAAX protease self-immunity
FORC48_0253	COG2252	PERMEase
FORC48_0255	COG5002	protein histidine kinase activity
FORC48_0257	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC48_0262	COG5002	protein histidine kinase activity
FORC48_0263	COG0745	RESPONSE REGULATOR receiver
FORC48_0268	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_0270	COG0463	Glycosyl transferase, family 2
FORC48_0270	COG1216	Glycosyl transferase, family 2
FORC48_0271	COG0697	spore germination
FORC48_0274	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC48_0275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC48_0276	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC48_0278	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC48_0281	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC48_0283	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC48_0285	COG0151	Belongs to the GarS family
FORC48_0291	COG0210	DNA helicase
FORC48_0293	COG4851	CamS sex pheromone cAM373 precursor
FORC48_0296	COG1335	isochorismatase
FORC48_0298	COG2011	ABC-type metal ion transport system permease component
FORC48_0299	COG1464	Belongs to the NlpA lipoprotein family
FORC48_0302	COG0003	Pfam Anion-transporting ATPase
FORC48_0303	COG1846	Transcriptional regulator
FORC48_0304	COG4682	membrane
FORC48_0308	COG1597	lipid kinase activity
FORC48_0310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC48_0312	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_0313	COG2076	Multidrug Resistance protein
FORC48_0315	COG2309	aminopeptidase activity
FORC48_0319	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_0321	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC48_0322	COG4807	Protein conserved in bacteria
FORC48_0328	COG1473	amidohydrolase
FORC48_0331	COG0450	alkyl hydroperoxide reductase
FORC48_0332	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FORC48_0334	COG0235	Class ii aldolase
FORC48_0335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_0336	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_0337	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_0340	COG0166	Belongs to the GPI family
FORC48_0346	COG5002	protein histidine kinase activity
FORC48_0350	COG3541	Predicted nucleotidyltransferase
FORC48_0351	COG2814	Major facilitator Superfamily
FORC48_0352	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_0352	COG0723	plastoquinol--plastocyanin reductase activity
FORC48_0354	COG0765	amino acid transport
FORC48_0355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_0357	COG0840	transmembrane signaling receptor activity
FORC48_0362	COG0549	Belongs to the carbamate kinase family
FORC48_0363	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_0365	COG0277	FAD linked oxidase domain protein
FORC48_0366	COG0366	Alpha amylase catalytic
FORC48_0367	COG2190	(PTS) system
FORC48_0367	COG1263	PTS System
FORC48_0367	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_0373	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC48_0377	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_0378	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_0379	COG1116	anion transmembrane transporter activity
FORC48_0380	COG0488	(ABC) transporter
FORC48_0389	COG2270	Major facilitator Superfamily
FORC48_0395	COG2310	stress, protein
FORC48_0396	COG2310	stress, protein
FORC48_0397	COG2310	stress, protein
FORC48_0398	COG0861	Integral membrane protein TerC family
FORC48_0400	COG3853	Toxic anion resistance protein (TelA)
FORC48_0403	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC48_0405	COG1295	ribonuclease BN
FORC48_0407	COG2217	Heavy metal translocating P-type atpase
FORC48_0408	COG0697	spore germination
FORC48_0410	COG0681	Belongs to the peptidase S26 family
FORC48_0412	COG0586	Pfam SNARE associated Golgi protein
FORC48_0415	COG3871	stress protein (general stress protein 26)
FORC48_0416	COG0387	Pfam Sodium calcium exchanger
FORC48_0418	COG0535	radical SAM domain protein
FORC48_0422	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC48_0423	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC48_0426	COG3829	transcription factor binding
FORC48_0428	COG0833	amino acid
FORC48_0429	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_0435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_0435	COG1263	PTS System
FORC48_0437	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_0440	COG0463	Glycosyl transferase, family 2
FORC48_0442	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC48_0442	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_0446	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC48_0450	COG1228	amidohydrolase
FORC48_0451	COG1090	epimerase
FORC48_0457	COG1988	membrane-bound metal-dependent
FORC48_0458	COG1194	a g-specific adenine glycosylase
FORC48_0465	COG1132	(ABC) transporter
FORC48_0466	COG4129	membrane
FORC48_0468	COG0067	glutamate synthase
FORC48_0468	COG0070	glutamate synthase
FORC48_0468	COG0069	glutamate synthase activity
FORC48_0470	COG4555	ABC transporter
FORC48_0474	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC48_0475	COG0735	belongs to the Fur family
FORC48_0481	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC48_0485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC48_0488	COG2766	serine protein kinase
FORC48_0492	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_0494	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC48_0495	COG2268	Band 7 protein
FORC48_0497	COG3290	protein histidine kinase activity
FORC48_0498	COG4565	transcriptional regulatory protein
FORC48_0499	COG2851	Citrate transporter
FORC48_0504	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC48_0505	COG3842	ATPase activity
FORC48_0506	COG1175	transmembrane transport
FORC48_0507	COG0395	ABC-type sugar transport system, permease component
FORC48_0510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC48_0511	COG0745	RESPONSE REGULATOR receiver
FORC48_0512	COG5002	protein histidine kinase activity
FORC48_0512	COG3850	Histidine kinase
FORC48_0515	COG4990	cell redox homeostasis
FORC48_0517	COG3290	protein histidine kinase activity
FORC48_0518	COG4565	transcriptional regulatory protein
FORC48_0519	COG3493	citrate carrier protein
FORC48_0520	COG0281	malic enzyme
FORC48_0523	COG0697	spore germination
FORC48_0524	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_0526	COG5002	protein histidine kinase activity
FORC48_0530	COG0456	acetyltransferase
FORC48_0530	COG0454	-acetyltransferase
FORC48_0531	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC48_0532	COG3383	formate dehydrogenase (NAD+) activity
FORC48_0533	COG2427	Protein of unknown function (DUF1641)
FORC48_0536	COG0531	amino acid
FORC48_0538	COG0640	Transcriptional regulator
FORC48_0539	COG2217	Heavy metal translocating P-type atpase
FORC48_0540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC48_0543	COG3227	Zinc metalloprotease (Elastase)
FORC48_0547	COG2720	vancomycin resistance protein
FORC48_0548	COG1316	TRANSCRIPTIONal
FORC48_0549	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_0550	COG0346	lactoylglutathione lyase activity
FORC48_0551	COG1253	flavin adenine dinucleotide binding
FORC48_0552	COG1027	Aspartate ammonia-lyase
FORC48_0553	COG1620	l-lactate permease
FORC48_0556	COG3104	oligopeptide transport
FORC48_0557	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_0558	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_0559	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_0561	COG2226	methyltransferase
FORC48_0563	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_0565	COG4548	von Willebrand factor, type A
FORC48_0566	COG0714	Associated with various cellular activities
FORC48_0570	COG0531	amino acid
FORC48_0571	COG2188	Transcriptional regulator
FORC48_0572	COG1263	PTS System
FORC48_0572	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_0573	COG0366	Alpha amylase catalytic
FORC48_0576	COG0697	spore germination
FORC48_0577	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC48_0580	COG1126	abc transporter atp-binding protein
FORC48_0581	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_0582	COG0765	amino acid transport
FORC48_0583	COG0765	amino acid transport
FORC48_0584	COG0833	amino acid
FORC48_0589	COG2378	regulation of single-species biofilm formation
FORC48_0590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC48_0591	COG5002	protein histidine kinase activity
FORC48_0596	COG0659	secondary active sulfate transmembrane transporter activity
FORC48_0599	COG2271	Major facilitator Superfamily
FORC48_0601	COG1846	Transcriptional regulator
FORC48_0602	COG0477	Major facilitator Superfamily
FORC48_0603	COG1609	Transcriptional regulator
FORC48_0604	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC48_0607	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_0608	COG1879	ABC-type sugar transport system periplasmic component
FORC48_0609	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC48_0612	COG1063	alcohol dehydrogenase
FORC48_0622	COG0840	transmembrane signaling receptor activity
FORC48_0623	COG3584	3D domain protein
FORC48_0623	COG1388	LysM domain
FORC48_0624	COG1476	TRANSCRIPTIONal
FORC48_0628	COG3104	oligopeptide transport
FORC48_0630	COG1114	Component of the transport system for branched-chain amino acids
FORC48_0633	COG1113	amino acid transport
FORC48_0634	COG2252	PERMEase
FORC48_0639	COG2153	protein acetylation
FORC48_0641	COG0475	glutathione-regulated potassium exporter activity
FORC48_0641	COG0569	domain protein
FORC48_0643	COG1845	cytochrome c oxidase, subunit III
FORC48_0644	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC48_0646	COG0833	amino acid
FORC48_0647	COG4990	cell redox homeostasis
FORC48_0650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_0651	COG0697	spore germination
FORC48_0652	COG0531	amino acid
FORC48_0655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_0656	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_0657	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_0657	COG1918	ferrous iron import across plasma membrane
FORC48_0658	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC48_0659	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_0660	COG0581	inorganic phosphate transmembrane transporter activity
FORC48_0661	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC48_0663	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FORC48_0667	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC48_0668	COG1116	anion transmembrane transporter activity
FORC48_0669	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_0670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_0671	COG0352	thiamine-phosphate diphosphorylase activity
FORC48_0672	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_0673	COG2104	thiamine diphosphate biosynthetic process
FORC48_0675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_0676	COG0351	phosphomethylpyrimidine kinase
FORC48_0685	COG2205	protein histidine kinase activity
FORC48_0686	COG2814	Major facilitator Superfamily
FORC48_0687	COG1846	Transcriptional regulator
FORC48_0689	COG2252	PERMEase
FORC48_0690	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_0693	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC48_0694	COG1621	beta-fructofuranosidase activity
FORC48_0695	COG1263	PTS System
FORC48_0695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_0696	COG1609	Transcriptional regulator
FORC48_0706	COG0778	Nitroreductase
FORC48_0707	COG2719	SpoVR family
FORC48_0709	COG3591	Belongs to the peptidase S1B family
FORC48_0714	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC48_0715	COG1937	Protein conserved in bacteria
FORC48_0716	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_0716	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_0717	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_0717	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_0718	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_0719	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_0719	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_0720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_0721	COG2210	Belongs to the sulfur carrier protein TusA family
FORC48_0722	COG0730	response to heat
FORC48_0724	COG1316	TRANSCRIPTIONal
FORC48_0725	COG0604	alcohol dehydrogenase
FORC48_0726	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC48_0729	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_0729	COG3711	transcriptional antiterminator
FORC48_0730	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_0731	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_0736	COG1388	LysM domain
FORC48_0736	COG3584	3D domain protein
FORC48_0737	COG0577	efflux transmembrane transporter activity
FORC48_0738	COG1136	(ABC) transporter
FORC48_0740	COG5522	Integral membrane protein (intg_mem_TP0381)
FORC48_0743	COG1114	Component of the transport system for branched-chain amino acids
FORC48_0744	COG3546	catalase activity
FORC48_0751	COG0586	Pfam SNARE associated Golgi protein
FORC48_0759	COG0531	amino acid
FORC48_0760	COG0475	glutathione-regulated potassium exporter activity
FORC48_0762	COG1737	Transcriptional regulator
FORC48_0764	COG1263	PTS System
FORC48_0764	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_0766	COG2259	Doxx family
FORC48_0770	COG1522	sequence-specific DNA binding
FORC48_0772	COG0300	oxidoreductase activity
FORC48_0775	COG2076	Multidrug Resistance protein
FORC48_0777	COG1309	transcriptional regulator
FORC48_0778	COG2814	Major facilitator Superfamily
FORC48_0779	COG1733	regulation of RNA biosynthetic process
FORC48_0782	COG4533	DNA binding
FORC48_0783	COG2211	Major facilitator Superfamily
FORC48_0785	COG0693	protein deglycase activity
FORC48_0786	COG0753	catalase activity
FORC48_0786	COG0693	protein deglycase activity
FORC48_0788	COG0531	amino acid
FORC48_0789	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC48_0791	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_0792	COG1132	(ABC) transporter
FORC48_0793	COG1132	(ABC) transporter
FORC48_0794	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_0795	COG0765	amino acid transport
FORC48_0796	COG1126	abc transporter atp-binding protein
FORC48_0799	COG0189	ligase activity
FORC48_0806	COG0028	Belongs to the TPP enzyme family
FORC48_0807	COG3527	Alpha-acetolactate decarboxylase
FORC48_0809	COG0561	phosphatase activity
FORC48_0811	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_0811	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_0812	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC48_0813	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_0816	COG0659	secondary active sulfate transmembrane transporter activity
FORC48_0817	COG2244	polysaccharide biosynthetic process
FORC48_0821	COG1024	Enoyl-CoA hydratase
FORC48_0825	COG1363	Peptidase, m42
FORC48_0832	COG0601	transmembrane transport
FORC48_0833	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_0834	COG0444	Belongs to the ABC transporter superfamily
FORC48_0835	COG4608	Belongs to the ABC transporter superfamily
FORC48_0840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_0844	COG0577	efflux transmembrane transporter activity
FORC48_0844	COG1136	(ABC) transporter
FORC48_0854	COG0477	Major facilitator Superfamily
FORC48_0855	COG3290	protein histidine kinase activity
FORC48_0856	COG4565	transcriptional regulatory protein
FORC48_0857	COG3181	Tripartite tricarboxylate transporter family receptor
FORC48_0866	COG1475	DNA binding
FORC48_0868	COG0305	Participates in initiation and elongation during chromosome replication
FORC48_0873	COG0477	Major facilitator Superfamily
FORC48_0877	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_0883	COG1073	alpha beta
FORC48_0894	COG1183	phosphatidylcholine synthase activity
FORC48_0897	COG2376	Dihydroxyacetone kinase
FORC48_0899	COG2376	Dihydroxyacetone kinase
FORC48_0906	COG3584	3D domain protein
FORC48_0906	COG1388	LysM domain
FORC48_0907	COG1388	LysM domain
FORC48_0907	COG0791	NLP P60 protein
FORC48_0908	COG2373	Large extracellular alpha-helical protein
FORC48_0913	COG0596	Alpha beta hydrolase
FORC48_0926	COG1191	sigma factor activity
FORC48_0928	COG2208	phosphoserine phosphatase activity
FORC48_0929	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC48_0930	COG0784	Response regulator, receiver
FORC48_0930	COG2205	protein histidine kinase activity
FORC48_0930	COG5002	protein histidine kinase activity
FORC48_0935	COG0393	Putative heavy-metal-binding
FORC48_0939	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FORC48_0944	COG0420	3'-5' exonuclease activity
FORC48_0945	COG4717	serine-type aminopeptidase activity
FORC48_0947	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_0951	COG0346	lactoylglutathione lyase activity
FORC48_0952	COG0346	lactoylglutathione lyase activity
FORC48_0953	COG0457	Tetratricopeptide repeat
FORC48_0955	COG2267	carboxylic ester hydrolase activity
FORC48_0960	COG2140	Oxalate decarboxylase
FORC48_0961	COG3620	sequence-specific DNA binding
FORC48_0962	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC48_0963	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC48_0965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC48_0966	COG1695	Transcriptional regulator
FORC48_0969	COG1595	DNA-templated transcription, initiation
FORC48_0974	COG3973	AAA domain
FORC48_0981	COG4980	gas vesicle protein
FORC48_0982	COG0537	adenosine 5'-monophosphoramidase activity
FORC48_0983	COG1131	(ABC) transporter
FORC48_0984	COG4473	ABC transporter
FORC48_0989	COG3402	PFAM membrane-flanked domain
FORC48_0990	COG3428	Bacterial PH domain
FORC48_0999	COG0697	spore germination
FORC48_1000	COG3402	PFAM membrane-flanked domain
FORC48_1001	COG3428	Bacterial PH domain
FORC48_1002	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_1003	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_1013	COG1309	transcriptional regulator
FORC48_1014	COG1511	domain protein
FORC48_1014	COG1511	domain protein
FORC48_1017	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_1018	COG1609	Transcriptional regulator
FORC48_1020	COG1234	tRNA 3'-trailer cleavage
FORC48_1021	COG0095	Lipoate-protein ligase
FORC48_1023	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_1025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC48_1027	COG4208	sulfate ABC transporter
FORC48_1030	COG3209	COG3209 Rhs family protein
FORC48_1054	COG1073	alpha beta
FORC48_1055	COG1408	metallophosphoesterase
FORC48_1056	COG1078	dGTPase activity
FORC48_1058	COG1595	DNA-templated transcription, initiation
FORC48_1059	COG3708	Transcriptional regulator
FORC48_1059	COG2207	Transcriptional regulator
FORC48_1062	COG2205	protein histidine kinase activity
FORC48_1063	COG0745	RESPONSE REGULATOR receiver
FORC48_1067	COG0501	Belongs to the peptidase M48B family
FORC48_1068	COG0840	transmembrane signaling receptor activity
FORC48_1069	COG3693	PFAM glycoside hydrolase, family 10
FORC48_1072	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC48_1073	COG2224	Isocitrate lyase
FORC48_1076	COG1278	Cold shock
FORC48_1081	COG0398	Pfam SNARE associated Golgi protein
FORC48_1094	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC48_1099	COG0367	asparagine synthase
FORC48_1101	COG0753	catalase activity
FORC48_1102	COG0004	ammonium transporteR
FORC48_1106	COG2996	Protein conserved in bacteria
FORC48_1109	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_1112	COG0561	phosphatase activity
FORC48_1117	COG2267	carboxylic ester hydrolase activity
FORC48_1121	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC48_1122	COG5504	Zn-dependent protease
FORC48_1125	COG0180	Tryptophanyl-tRNA synthetase
FORC48_1127	COG4166	transmembrane transport
FORC48_1128	COG0601	transmembrane transport
FORC48_1129	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_1130	COG0444	Belongs to the ABC transporter superfamily
FORC48_1131	COG4608	Belongs to the ABC transporter superfamily
FORC48_1132	COG0534	Mate efflux family protein
FORC48_1133	COG4166	transmembrane transport
FORC48_1135	COG1393	Belongs to the ArsC family
FORC48_1136	COG0861	Integral membrane protein TerC family
FORC48_1140	COG1164	Oligoendopeptidase f
FORC48_1143	COG2346	COG2346, Truncated hemoglobins
FORC48_1144	COG4116	CYTH
FORC48_1146	COG2357	RelA SpoT domain protein
FORC48_1148	COG0564	pseudouridine synthase activity
FORC48_1151	COG0772	Belongs to the SEDS family
FORC48_1152	COG1216	Glycosyl transferase, family 2
FORC48_1156	COG0457	Tetratricopeptide repeat
FORC48_1156	COG0463	Glycosyl transferase, family 2
FORC48_1160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC48_1163	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC48_1172	COG2153	protein acetylation
FORC48_1174	COG2382	esterase
FORC48_1178	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_1181	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC48_1181	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC48_1189	COG1620	l-lactate permease
FORC48_1190	COG5634	Uncharacterized conserved protein (DUF2278)
FORC48_1200	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_1203	COG1476	TRANSCRIPTIONal
FORC48_1214	COG1686	Belongs to the peptidase S11 family
FORC48_1215	COG0681	Belongs to the peptidase S26 family
FORC48_1222	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_1224	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC48_1225	COG1177	transmembrane transport
FORC48_1226	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC48_1228	COG2409	Drug exporters of the RND superfamily
FORC48_1230	COG0564	pseudouridine synthase activity
FORC48_1232	COG2340	Cysteine-rich secretory protein family
FORC48_1233	COG0247	lactate metabolic process
FORC48_1234	COG0277	FAD linked oxidase domain protein
FORC48_1235	COG3835	regulator
FORC48_1237	COG0745	RESPONSE REGULATOR receiver
FORC48_1238	COG5002	protein histidine kinase activity
FORC48_1239	COG2186	Transcriptional regulator
FORC48_1243	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC48_1245	COG2116	formate transmembrane transporter activity
FORC48_1247	COG0861	Integral membrane protein TerC family
FORC48_1248	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_1250	COG2030	dehydratase
FORC48_1254	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_1255	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC48_1257	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_1260	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC48_1261	COG3842	ATPase activity
FORC48_1266	COG1349	DNA-binding transcription factor activity
FORC48_1269	COG0235	Class ii aldolase
FORC48_1271	COG2861	carbohydrate metabolic process
FORC48_1273	COG3852	Histidine kinase
FORC48_1274	COG1846	Transcriptional regulator
FORC48_1276	COG2318	DinB family
FORC48_1279	COG5002	protein histidine kinase activity
FORC48_1281	COG0720	synthase
FORC48_1284	COG4873	Protein conserved in bacteria
FORC48_1290	COG1780	Probably involved in ribonucleotide reductase function
FORC48_1291	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC48_1292	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC48_1293	COG1725	Transcriptional regulator
FORC48_1294	COG1131	(ABC) transporter
FORC48_1296	COG1131	(ABC) transporter
FORC48_1297	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC48_1298	COG1266	CAAX protease self-immunity
FORC48_1300	COG1522	sequence-specific DNA binding
FORC48_1302	COG1335	isochorismatase
FORC48_1304	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC48_1306	COG2070	2-Nitropropane dioxygenase
FORC48_1307	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC48_1309	COG1696	Membrane protein involved in D-alanine export
FORC48_1314	COG0716	FMN binding
FORC48_1325	COG1846	Transcriptional regulator
FORC48_1327	COG1301	dicarboxylic acid transport
FORC48_1328	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_1329	COG4709	membrane
FORC48_1330	COG3874	Sporulation protein YtfJ
FORC48_1335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_1336	COG0028	Belongs to the TPP enzyme family
FORC48_1337	COG0440	acetolactate synthase activity
FORC48_1352	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC48_1355	COG1183	phosphatidylcholine synthase activity
FORC48_1356	COG1368	sulfuric ester hydrolase activity
FORC48_1358	COG0019	diaminopimelate decarboxylase activity
FORC48_1362	COG0529	Catalyzes the synthesis of activated sulfate
FORC48_1363	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC48_1367	COG1648	precorrin-2 dehydrogenase activity
FORC48_1368	COG0733	neurotransmitter:sodium symporter activity
FORC48_1373	COG1757	Na H antiporter
FORC48_1376	COG4758	membrane
FORC48_1377	COG4585	Histidine kinase
FORC48_1378	COG2197	response regulator
FORC48_1380	COG1114	Component of the transport system for branched-chain amino acids
FORC48_1391	COG0730	response to heat
FORC48_1392	COG0306	phosphate transporter
FORC48_1393	COG1392	Phosphate transport regulator
FORC48_1394	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_1397	COG3852	Histidine kinase
FORC48_1398	COG1801	Protein of unknown function DUF72
FORC48_1401	COG0582	viral genome integration into host DNA
FORC48_1402	COG5002	protein histidine kinase activity
FORC48_1405	COG0392	lysyltransferase activity
FORC48_1405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FORC48_1408	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC48_1409	COG1686	Belongs to the peptidase S11 family
FORC48_1410	COG2715	membrane protein required for spore maturation
FORC48_1411	COG0700	Nucleoside recognition
FORC48_1412	COG1187	pseudouridine synthase activity
FORC48_1414	COG1333	cytochrome c biogenesis protein
FORC48_1415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC48_1416	COG0745	RESPONSE REGULATOR receiver
FORC48_1417	COG5002	protein histidine kinase activity
FORC48_1418	COG2096	Adenosyltransferase
FORC48_1421	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FORC48_1422	COG1141	Ferredoxin
FORC48_1424	COG0514	ATP-dependent DNA helicase (RecQ)
FORC48_1425	COG1266	CAAX protease self-immunity
FORC48_1427	COG1408	metallophosphoesterase
FORC48_1428	COG0789	Transcriptional regulator
FORC48_1430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC48_1434	COG0492	ferredoxin-NADP+ reductase activity
FORC48_1435	COG0252	asparaginase activity
FORC48_1450	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_1453	COG0142	geranyltranstransferase activity
FORC48_1455	COG0142	geranyltranstransferase activity
FORC48_1460	COG0457	Tetratricopeptide repeat
FORC48_1464	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC48_1465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC48_1465	COG2010	Cytochrome c
FORC48_1466	COG4347	Protein of unknown function (DUF1405)
FORC48_1469	COG2738	Putative neutral zinc metallopeptidase
FORC48_1471	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_1472	COG1694	Mazg nucleotide pyrophosphohydrolase
FORC48_1476	COG0438	transferase activity, transferring glycosyl groups
FORC48_1483	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC48_1483	COG1199	ATP-dependent helicase activity
FORC48_1487	COG3935	DnaD domain protein
FORC48_1488	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC48_1490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_1490	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_1501	COG0116	Belongs to the methyltransferase superfamily
FORC48_1505	COG0457	Tetratricopeptide repeat
FORC48_1510	COG1199	ATP-dependent helicase activity
FORC48_1511	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC48_1513	COG0024	Methionine aminopeptidase
FORC48_1515	COG2233	PERMEase
FORC48_1516	COG2311	Membrane
FORC48_1518	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_1520	COG0456	acetyltransferase
FORC48_1525	COG0754	glutathionylspermidine amidase activity
FORC48_1528	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_1531	COG3944	biosynthesis protein
FORC48_1533	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC48_1536	COG1215	transferase activity, transferring glycosyl groups
FORC48_1537	COG0438	transferase activity, transferring glycosyl groups
FORC48_1540	COG0454	-acetyltransferase
FORC48_1544	COG0328	RNA-DNA hybrid ribonuclease activity
FORC48_1551	COG3403	YqcI/YcgG family
FORC48_1552	COG1280	lysine exporter protein (LysE YggA)
FORC48_1556	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_1557	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_1559	COG0475	glutathione-regulated potassium exporter activity
FORC48_1560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_1561	COG4978	Transcriptional regulator
FORC48_1561	COG0789	Transcriptional regulator
FORC48_1563	COG2323	membrane
FORC48_1564	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC48_1571	COG1923	regulation of RNA biosynthetic process
FORC48_1573	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC48_1574	COG1360	Flagellar Motor Protein
FORC48_1575	COG2201	protein-glutamate methylesterase activity
FORC48_1576	COG2198	Histidine kinase
FORC48_1576	COG0643	Histidine kinase
FORC48_1577	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_1577	COG1776	CheC inhibitor of MCP methylation
FORC48_1580	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC48_1584	COG1256	bacterial-type flagellum assembly
FORC48_1585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_1589	COG1815	bacterial-type flagellum-dependent cell motility
FORC48_1590	COG1558	bacterial-type flagellum-dependent cell motility
FORC48_1591	COG1677	Flagellar hook-basal body complex protein FliE
FORC48_1592	COG1766	The M ring may be actively involved in energy transduction
FORC48_1593	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_1595	COG1157	protein secretion by the type III secretion system
FORC48_1599	COG1749	Flagellar hook protein flgE
FORC48_1602	COG0784	Response regulator, receiver
FORC48_1602	COG0835	chemotaxis
FORC48_1604	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_1605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_1606	COG0741	lytic transglycosylase activity
FORC48_1608	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_1609	COG1776	CheC inhibitor of MCP methylation
FORC48_1609	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_1611	COG1338	Plays a role in the flagellum-specific transport system
FORC48_1612	COG1987	bacterial-type flagellum assembly
FORC48_1614	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC48_1615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC48_1616	COG1419	protein localization to endoplasmic reticulum
FORC48_1617	COG4786	Flagellar basal body rod
FORC48_1618	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC48_1624	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_1632	COG1177	transmembrane transport
FORC48_1633	COG1234	tRNA 3'-trailer cleavage
FORC48_1639	COG0406	alpha-ribazole phosphatase activity
FORC48_1645	COG0367	asparagine synthase
FORC48_1651	COG1802	Transcriptional regulator
FORC48_1652	COG0697	spore germination
FORC48_1654	COG0523	cobalamin synthesis protein
FORC48_1655	COG0701	Predicted permease
FORC48_1658	COG1757	Na H antiporter
FORC48_1659	COG0789	Transcriptional regulator
FORC48_1665	COG0534	Mate efflux family protein
FORC48_1666	COG3340	Belongs to the peptidase S51 family
FORC48_1670	COG0785	Cytochrome C biogenesis protein
FORC48_1671	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_1675	COG2733	membrane
FORC48_1682	COG1131	(ABC) transporter
FORC48_1686	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_1687	COG0528	UMP kinase activity
FORC48_1690	COG1027	Aspartate ammonia-lyase
FORC48_1691	COG0281	malic enzyme
FORC48_1692	COG4191	Histidine kinase
FORC48_1693	COG0784	Response regulator, receiver
FORC48_1695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_1699	COG3620	sequence-specific DNA binding
FORC48_1707	COG2814	Major facilitator Superfamily
FORC48_1712	COG0477	Major facilitator Superfamily
FORC48_1715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC48_1716	COG2223	nitrite transmembrane transporter activity
FORC48_1717	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_1721	COG0733	neurotransmitter:sodium symporter activity
FORC48_1724	COG5566	PFAM Mor transcription activator
FORC48_1725	COG2323	membrane
FORC48_1730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_1732	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_1733	COG0028	Belongs to the TPP enzyme family
FORC48_1737	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC48_1741	COG2814	Major facilitator Superfamily
FORC48_1742	COG3384	dioxygenase
FORC48_1744	COG3279	Response regulator of the LytR AlgR family
FORC48_1745	COG0427	acetyl-CoA hydrolase
FORC48_1749	COG4166	transmembrane transport
FORC48_1750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_1754	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC48_1757	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC48_1759	COG0531	amino acid
FORC48_1766	COG2309	aminopeptidase activity
FORC48_1769	COG0456	acetyltransferase
FORC48_1771	COG1266	CAAX protease self-immunity
FORC48_1772	COG1309	transcriptional regulator
FORC48_1773	COG2390	Transcriptional regulator
FORC48_1775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_1776	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC48_1778	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC48_1782	COG0583	DNA-binding transcription factor activity
FORC48_1785	COG0006	proline dipeptidase activity
FORC48_1787	COG2132	Multicopper oxidase
FORC48_1790	COG1309	transcriptional regulator
FORC48_1791	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FORC48_1805	COG1114	Component of the transport system for branched-chain amino acids
FORC48_1807	COG1910	domain protein
FORC48_1811	COG2318	DinB family
FORC48_1813	COG1280	lysine exporter protein (LysE YggA)
FORC48_1814	COG3403	YqcI/YcgG family
FORC48_1817	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC48_1818	COG0561	phosphatase activity
FORC48_1819	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC48_1821	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC48_1822	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_1824	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_1827	COG1276	copper resistance
FORC48_1827	COG2372	response to copper ion
FORC48_1828	COG4549	nuclear export factor GLE1
FORC48_1829	COG0697	spore germination
FORC48_1830	COG0583	DNA-binding transcription factor activity
FORC48_1831	COG1959	2 iron, 2 sulfur cluster binding
FORC48_1832	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC48_1833	COG0778	Nitroreductase
FORC48_1836	COG0628	permease
FORC48_1838	COG1231	oxidoreductase activity
FORC48_1840	COG0523	cobalamin synthesis protein
FORC48_1842	COG0411	ABC transporter
FORC48_1846	COG0583	DNA-binding transcription factor activity
FORC48_1853	COG1271	oxidase subunit
FORC48_1854	COG1294	oxidase, subunit
FORC48_1855	COG4988	ABC transporter
FORC48_1856	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC48_1858	COG1216	Glycosyl transferase, family 2
FORC48_1866	COG1686	Belongs to the peptidase S11 family
FORC48_1869	COG0791	NLP P60 protein
FORC48_1869	COG1388	LysM domain
FORC48_1871	COG1132	(ABC) transporter
FORC48_1872	COG0745	RESPONSE REGULATOR receiver
FORC48_1873	COG5002	protein histidine kinase activity
FORC48_1874	COG0300	oxidoreductase activity
FORC48_1876	COG0726	polysaccharide deacetylase
FORC48_1880	COG0460	homoserine dehydrogenase
FORC48_1885	COG1316	TRANSCRIPTIONal
FORC48_1887	COG0745	RESPONSE REGULATOR receiver
FORC48_1888	COG5002	protein histidine kinase activity
FORC48_1889	COG0726	polysaccharide deacetylase
FORC48_1891	COG1285	pathogenesis
FORC48_1892	COG1247	-acetyltransferase
FORC48_1894	COG4264	IucA IucC family
FORC48_1895	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_1898	COG1082	Xylose isomerase domain protein TIM barrel
FORC48_1900	COG2814	Major facilitator Superfamily
FORC48_1901	COG1279	arginine transmembrane transporter activity
FORC48_1902	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_1904	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC48_1911	COG0577	efflux transmembrane transporter activity
FORC48_1912	COG2002	toxin-antitoxin pair type II binding
FORC48_1913	COG1404	Belongs to the peptidase S8 family
FORC48_1914	COG0640	Transcriptional regulator
FORC48_1916	COG0667	Aldo Keto reductase
FORC48_1917	COG2814	Major facilitator Superfamily
FORC48_1919	COG3152	Membrane
FORC48_1924	COG0840	transmembrane signaling receptor activity
FORC48_1927	COG3949	Membrane
FORC48_1928	COG0783	Belongs to the Dps family
FORC48_1931	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC48_1933	COG1231	oxidoreductase activity
FORC48_1934	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_1935	COG4989	oxidoreductase activity
FORC48_1936	COG0523	cobalamin synthesis protein
FORC48_1937	COG0456	acetyltransferase
FORC48_1938	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC48_1940	COG0702	epimerase
FORC48_1942	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC48_1944	COG4166	transmembrane transport
FORC48_1949	COG5337	Spore coat protein CotH
FORC48_1950	COG1051	belongs to the nudix hydrolase family
FORC48_1951	COG0586	Pfam SNARE associated Golgi protein
FORC48_1952	COG2244	polysaccharide biosynthetic process
FORC48_1954	COG0701	Predicted permease
FORC48_1955	COG3689	TIGRFAM TIGR03943 family protein
FORC48_1956	COG1607	acyl-coa hydrolase
FORC48_1959	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_1962	COG0702	epimerase
FORC48_1963	COG2839	Protein conserved in bacteria
FORC48_1964	COG1253	flavin adenine dinucleotide binding
FORC48_1967	COG1114	Component of the transport system for branched-chain amino acids
FORC48_1968	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC48_1972	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_1974	COG1876	peptidase activity
FORC48_1976	COG0154	amidase activity
FORC48_1977	COG2211	Major facilitator Superfamily
FORC48_1980	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_1982	COG0561	phosphatase activity
FORC48_1985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC48_1988	COG1819	glycosyl
FORC48_1989	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_1990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_1996	COG0456	acetyltransferase
FORC48_2000	COG1511	domain protein
FORC48_2000	COG0842	Transport permease protein
FORC48_2003	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_2019	COG3874	Sporulation protein YtfJ
FORC48_2024	COG2226	methyltransferase
FORC48_2029	COG0346	lactoylglutathione lyase activity
FORC48_2031	COG0604	alcohol dehydrogenase
FORC48_2032	COG1595	DNA-templated transcription, initiation
FORC48_2037	COG0386	Belongs to the glutathione peroxidase family
FORC48_2038	COG1305	Transglutaminase-like
FORC48_2039	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FORC48_2040	COG0714	Associated with various cellular activities
FORC48_2041	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FORC48_2042	COG1140	nitrate reductase beta subunit
FORC48_2043	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FORC48_2044	COG2181	nitrate reductase activity
FORC48_2045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_2046	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC48_2047	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_2048	COG0303	'Molybdopterin
FORC48_2049	COG0314	molybdopterin synthase activity
FORC48_2051	COG2223	nitrite transmembrane transporter activity
FORC48_2054	COG1648	precorrin-2 dehydrogenase activity
FORC48_2056	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC48_2056	COG1587	Uroporphyrinogen-III synthase
FORC48_2057	COG2146	nitrite reductase [NAD(P)H] activity
FORC48_2058	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC48_2066	COG2359	stage V sporulation protein S
FORC48_2071	COG2801	Transposase and inactivated derivatives
FORC48_2075	COG0457	Tetratricopeptide repeat
FORC48_2080	COG1418	mRNA catabolic process
FORC48_2081	COG0488	(ABC) transporter
FORC48_2084	COG0629	single-stranded DNA binding
FORC48_2088	COG1413	lyase activity
FORC48_2091	COG2521	methyltransferase
FORC48_2091	COG2136	Putative SAM-dependent methyltransferase
FORC48_2092	COG0018	arginyl-trna synthetase
FORC48_2101	COG0017	Asparaginyl-tRNA synthetase
FORC48_2102	COG0733	neurotransmitter:sodium symporter activity
FORC48_2107	COG2610	gluconate transmembrane transporter activity
FORC48_2109	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_2111	COG0456	acetyltransferase
FORC48_2113	COG3655	Transcriptional regulator
FORC48_2114	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC48_2116	COG1131	(ABC) transporter
FORC48_2117	COG4473	ABC transporter
FORC48_2119	COG0546	phosphoglycolate phosphatase activity
FORC48_2122	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_2125	COG0768	penicillin binding
FORC48_2127	COG0204	Acyl-transferase
FORC48_2128	COG1272	protein, Hemolysin III
FORC48_2130	COG0805	protein transport
FORC48_2132	COG1307	EDD domain protein, DegV family
FORC48_2135	COG1999	signal sequence binding
FORC48_2136	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC48_2137	COG0367	asparagine synthase
FORC48_2140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_2141	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_2142	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_2146	COG1335	isochorismatase
FORC48_2148	COG0668	transmembrane transport
FORC48_2149	COG4585	Histidine kinase
FORC48_2149	COG2203	Gaf domain
FORC48_2150	COG2197	response regulator
FORC48_2151	COG1737	Transcriptional regulator
FORC48_2152	COG0384	phenazine biosynthesis protein PhzF
FORC48_2153	COG1064	alcohol dehydrogenase
FORC48_2155	COG2801	Transposase and inactivated derivatives
FORC48_2160	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC48_2167	COG1125	glycine betaine transport
FORC48_2167	COG0517	IMP dehydrogenase activity
FORC48_2168	COG1174	glycine betaine transport
FORC48_2175	COG1253	flavin adenine dinucleotide binding
FORC48_2176	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_2177	COG5506	Protein of unknown function (DUF1694)
FORC48_2180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_2181	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC48_2182	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FORC48_2183	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_2184	COG0456	acetyltransferase
FORC48_2185	COG3829	transcription factor binding
FORC48_2186	COG1509	lysine 2,3-aminomutase activity
FORC48_2193	COG0515	serine threonine protein kinase
FORC48_2193	COG4991	sh3 domain protein
FORC48_2193	COG3064	Membrane
FORC48_2195	COG0671	phosphoesterase, PA-phosphatase related
FORC48_2196	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC48_2198	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_2212	COG0300	oxidoreductase activity
FORC48_2216	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_2216	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_2218	COG2814	Major facilitator Superfamily
FORC48_2219	COG4841	protein insertion into membrane
FORC48_2220	COG0372	Belongs to the citrate synthase family
FORC48_2221	COG2079	MmgE PrpD family protein
FORC48_2222	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC48_2223	COG1960	acyl-CoA dehydrogenase activity
FORC48_2224	COG2084	Dehydrogenase
FORC48_2226	COG1280	lysine exporter protein (LysE YggA)
FORC48_2227	COG1024	Enoyl-CoA hydratase
FORC48_2230	COG0420	3'-5' exonuclease activity
FORC48_2231	COG0419	ATPase involved in DNA repair
FORC48_2238	COG2223	nitrite transmembrane transporter activity
FORC48_2239	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_2240	COG1169	isochorismate synthase
FORC48_2241	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC48_2242	COG1535	isochorismatase
FORC48_2242	COG3433	isochorismatase activity
FORC48_2243	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC48_2244	COG3251	PFAM MbtH domain protein
FORC48_2245	COG2814	Major facilitator Superfamily
FORC48_2248	COG0776	regulation of translation
FORC48_2250	COG2318	DinB family
FORC48_2252	COG1115	amino acid carrier protein
FORC48_2258	COG1187	pseudouridine synthase activity
FORC48_2259	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC48_2260	COG1136	(ABC) transporter
FORC48_2262	COG2814	Major facilitator Superfamily
FORC48_2265	COG0028	Belongs to the TPP enzyme family
FORC48_2273	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_2275	COG2267	carboxylic ester hydrolase activity
FORC48_2277	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_2283	COG1247	-acetyltransferase
FORC48_2290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_2296	COG0583	DNA-binding transcription factor activity
FORC48_2297	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC48_2301	COG0583	DNA-binding transcription factor activity
FORC48_2302	COG2258	MOSC domain
FORC48_2305	COG1132	(ABC) transporter
FORC48_2306	COG1132	(ABC) transporter
FORC48_2313	COG1396	sequence-specific DNA binding
FORC48_2319	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_2320	COG1595	DNA-templated transcription, initiation
FORC48_2325	COG1649	PFAM Uncharacterised BCR, COG1649
FORC48_2330	COG2971	BadF BadG BcrA BcrD
FORC48_2334	COG1846	Transcriptional regulator
FORC48_2338	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_2345	COG1309	transcriptional regulator
FORC48_2349	COG0500	methyltransferase
FORC48_2349	COG3615	Tellurite resistance protein tehB
FORC48_2351	COG2226	methyltransferase
FORC48_2352	COG3961	Belongs to the TPP enzyme family
FORC48_2353	COG1846	Transcriptional regulator
FORC48_2359	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC48_2365	COG2002	toxin-antitoxin pair type II binding
FORC48_2367	COG0730	response to heat
FORC48_2368	COG0110	maltose O-acetyltransferase activity
FORC48_2369	COG1686	Belongs to the peptidase S11 family
FORC48_2371	COG2814	Major facilitator Superfamily
FORC48_2377	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_2383	COG0741	lytic transglycosylase activity
FORC48_2384	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_2394	COG1309	transcriptional regulator
FORC48_2396	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_2397	COG0768	penicillin binding
FORC48_2398	COG1595	DNA-templated transcription, initiation
FORC48_2403	COG1408	metallophosphoesterase
FORC48_2405	COG1131	(ABC) transporter
FORC48_2407	COG1309	transcriptional regulator
FORC48_2410	COG1960	acyl-CoA dehydrogenase activity
FORC48_2411	COG0439	Biotin carboxylase
FORC48_2412	COG0511	ligase activity, forming carbon-carbon bonds
FORC48_2413	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC48_2414	COG1024	Enoyl-CoA hydratase
FORC48_2415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC48_2416	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_2422	COG0572	uridine kinase
FORC48_2423	COG2318	DinB family
FORC48_2424	COG2318	DinB family
FORC48_2426	COG1686	Belongs to the peptidase S11 family
FORC48_2431	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC48_2434	COG3227	Zinc metalloprotease (Elastase)
FORC48_2435	COG2207	Transcriptional regulator
FORC48_2441	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC48_2443	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_2444	COG1733	regulation of RNA biosynthetic process
FORC48_2448	COG1942	4-Oxalocrotonate Tautomerase
FORC48_2449	COG0583	DNA-binding transcription factor activity
FORC48_2453	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_2455	COG2368	4-hydroxyphenylacetate
FORC48_2458	COG1063	alcohol dehydrogenase
FORC48_2460	COG2323	membrane
FORC48_2463	COG3386	PFAM SMP-30 Gluconolaconase
FORC48_2466	COG3773	Cell wall hydrolase
FORC48_2468	COG0745	RESPONSE REGULATOR receiver
FORC48_2469	COG2205	protein histidine kinase activity
FORC48_2475	COG0825	malonyl-CoA metabolic process
FORC48_2477	COG1136	(ABC) transporter
FORC48_2478	COG0577	efflux transmembrane transporter activity
FORC48_2482	COG0460	homoserine dehydrogenase
FORC48_2483	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_2485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC48_2490	COG0582	viral genome integration into host DNA
FORC48_2520	COG0582	viral genome integration into host DNA
FORC48_2545	COG4824	toxin secretion phage lysis holin
FORC48_2556	COG2124	cytochrome p450
FORC48_2563	COG0561	phosphatase activity
FORC48_2564	COG5002	protein histidine kinase activity
FORC48_2567	COG1819	glycosyl
FORC48_2568	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_2573	COG2205	protein histidine kinase activity
FORC48_2584	COG0604	alcohol dehydrogenase
FORC48_2585	COG0671	phosphoesterase, PA-phosphatase related
FORC48_2598	COG2814	Major facilitator Superfamily
FORC48_2599	COG0789	Transcriptional regulator
FORC48_2599	COG4978	Transcriptional regulator
FORC48_2604	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_2608	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_2609	COG0697	spore germination
FORC48_2618	COG2223	nitrite transmembrane transporter activity
FORC48_2621	COG0592	DNA-directed DNA polymerase activity
FORC48_2625	COG3878	Protein conserved in bacteria
FORC48_2630	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC48_2638	COG0322	excinuclease ABC activity
FORC48_2646	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_2654	COG0745	RESPONSE REGULATOR receiver
FORC48_2655	COG5002	protein histidine kinase activity
FORC48_2658	COG1136	(ABC) transporter
FORC48_2659	COG0577	efflux transmembrane transporter activity
FORC48_2660	COG1073	alpha beta
FORC48_2662	COG0076	glutamate decarboxylase activity
FORC48_2665	COG1523	belongs to the glycosyl hydrolase 13 family
FORC48_2666	COG3227	Zinc metalloprotease (Elastase)
FORC48_2667	COG0737	Belongs to the 5'-nucleotidase family
FORC48_2672	COG0201	protein transport
FORC48_2673	COG0697	spore germination
FORC48_2674	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_2676	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC48_2682	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_2685	COG2959	enzyme of heme biosynthesis
FORC48_2686	COG3773	Cell wall hydrolase
FORC48_2686	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_2693	COG1309	transcriptional regulator
FORC48_2698	COG3284	Transcriptional regulator
FORC48_2702	COG1349	DNA-binding transcription factor activity
FORC48_2705	COG1959	2 iron, 2 sulfur cluster binding
FORC48_2708	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_2709	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_2710	COG0022	dehydrogenase e1 component
FORC48_2711	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_2714	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_2715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC48_2715	COG0456	acetyltransferase
FORC48_2722	COG4176	ABC-type proline glycine betaine transport system permease component
FORC48_2723	COG4175	Glycine betaine
FORC48_2723	COG0517	IMP dehydrogenase activity
FORC48_2725	COG0740	serine-type endopeptidase activity
FORC48_2729	COG2153	protein acetylation
FORC48_2730	COG3397	chitin binding
FORC48_2731	COG1819	glycosyl
FORC48_2734	COG2205	protein histidine kinase activity
FORC48_2735	COG2226	methyltransferase
FORC48_2736	COG2315	Protein conserved in bacteria
FORC48_2747	COG3973	AAA domain
FORC48_2750	COG0514	ATP-dependent DNA helicase (RecQ)
FORC48_2758	COG4637	Psort location Cytoplasmic, score
FORC48_2761	COG3397	chitin binding
FORC48_2764	COG1162	GTPase activity
FORC48_2765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC48_2766	COG1115	amino acid carrier protein
FORC48_2767	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_2768	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC48_2770	COG3938	Belongs to the proline racemase family
FORC48_2771	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_2780	COG1078	dGTPase activity
FORC48_2781	COG0586	Pfam SNARE associated Golgi protein
FORC48_2783	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC48_2785	COG4166	transmembrane transport
FORC48_2787	COG4948	Mandelate Racemase Muconate Lactonizing
FORC48_2790	COG0667	Aldo Keto reductase
FORC48_2799	COG5002	protein histidine kinase activity
FORC48_2799	COG3850	Histidine kinase
FORC48_2800	COG0745	RESPONSE REGULATOR receiver
FORC48_2807	COG1164	Oligoendopeptidase f
FORC48_2808	COG1307	EDD domain protein, DegV family
FORC48_2817	COG2814	Major facilitator Superfamily
FORC48_2819	COG1664	Polymer-forming cytoskeletal
FORC48_2820	COG0789	Transcriptional regulator
FORC48_2821	COG4533	DNA binding
FORC48_2822	COG2814	Major facilitator Superfamily
FORC48_2822	COG0477	Major facilitator Superfamily
FORC48_2826	COG2261	transglycosylase associated protein
FORC48_2829	COG2226	methyltransferase
FORC48_2838	COG0436	Aminotransferase
FORC48_2839	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC48_2841	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FORC48_2850	COG0628	permease
FORC48_2853	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC48_2854	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_2855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_2863	COG2746	aminoglycoside 3-N-acetyltransferase activity
FORC48_2865	COG0697	spore germination
FORC48_2867	COG2318	DinB family
FORC48_2871	COG4912	Dna alkylation repair
FORC48_2873	COG0346	lactoylglutathione lyase activity
FORC48_2874	COG0726	polysaccharide deacetylase
FORC48_2876	COG0861	Integral membrane protein TerC family
FORC48_2877	COG1368	sulfuric ester hydrolase activity
FORC48_2878	COG0488	(ABC) transporter
FORC48_2880	COG1033	growth of symbiont in host cell
FORC48_2880	COG2409	Drug exporters of the RND superfamily
FORC48_2881	COG1309	transcriptional regulator
FORC48_2884	COG0287	Prephenate dehydrogenase
FORC48_2887	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC48_2887	COG1605	Chorismate mutase
FORC48_2895	COG3584	3D domain protein
FORC48_2895	COG1388	LysM domain
FORC48_2897	COG0346	lactoylglutathione lyase activity
FORC48_2898	COG0277	FAD linked oxidase domain protein
FORC48_2904	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_2905	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_2906	COG1129	ABC transporter
FORC48_2908	COG2390	Transcriptional regulator
FORC48_2909	COG1070	Carbohydrate kinase
FORC48_2914	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_2918	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_2921	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_2922	COG4187	Peptidase family M20/M25/M40
FORC48_2923	COG1414	Transcriptional regulator
FORC48_2924	COG0833	amino acid
FORC48_2926	COG3239	Fatty acid desaturase
FORC48_2928	COG2720	vancomycin resistance protein
FORC48_2929	COG1785	Belongs to the alkaline phosphatase family
FORC48_2931	COG3655	Transcriptional regulator
FORC48_2935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_2936	COG0346	lactoylglutathione lyase activity
FORC48_2941	COG0714	Associated with various cellular activities
FORC48_2946	COG0463	Glycosyl transferase, family 2
FORC48_2952	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC48_2953	COG0753	catalase activity
FORC48_2961	COG0714	Associated with various cellular activities
FORC48_2969	COG2801	Transposase and inactivated derivatives
FORC48_2971	COG0778	Nitroreductase
FORC48_2972	COG1846	Transcriptional regulator
FORC48_2976	COG4884	unkown
FORC48_2976	COG3831	ATPase activity
FORC48_2981	COG0456	acetyltransferase
FORC48_2984	COG0697	spore germination
FORC48_2985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_2995	COG0730	response to heat
FORC48_2997	COG0833	amino acid
FORC48_2999	COG4335	DNA alkylation repair
FORC48_3013	COG1984	allophanate hydrolase subunit 2
FORC48_3014	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC48_3015	COG1414	Transcriptional regulator
FORC48_3018	COG0640	Transcriptional regulator
FORC48_3020	COG1960	acyl-CoA dehydrogenase activity
FORC48_3028	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FORC48_3034	COG3848	Pyruvate phosphate dikinase
FORC48_3034	COG0574	Belongs to the PEP-utilizing enzyme family
FORC48_3036	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_3040	COG1063	alcohol dehydrogenase
FORC48_3041	COG1027	Aspartate ammonia-lyase
FORC48_3042	COG0252	asparaginase activity
FORC48_3043	COG1396	sequence-specific DNA binding
FORC48_3048	COG5002	protein histidine kinase activity
FORC48_3053	COG2207	Transcriptional regulator
FORC48_3055	COG0322	excinuclease ABC activity
FORC48_3056	COG0531	amino acid
FORC48_3057	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_3059	COG0281	malic enzyme
FORC48_3062	COG0531	amino acid
FORC48_3063	COG0697	spore germination
FORC48_3065	COG0784	Response regulator, receiver
FORC48_3066	COG4191	Histidine kinase
FORC48_3069	COG1115	amino acid carrier protein
FORC48_3074	COG0737	Belongs to the 5'-nucleotidase family
FORC48_3075	COG2267	carboxylic ester hydrolase activity
FORC48_3076	COG1335	isochorismatase
FORC48_3080	COG0583	DNA-binding transcription factor activity
FORC48_3081	COG1846	Transcriptional regulator
FORC48_3082	COG0598	Magnesium transport protein CorA
FORC48_3086	COG1073	alpha beta
FORC48_3090	COG0415	Belongs to the DNA photolyase family
FORC48_3092	COG2814	Major facilitator Superfamily
FORC48_3094	COG0657	acetylesterase activity
FORC48_3095	COG0288	reversible hydration of carbon dioxide
FORC48_3097	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC48_3098	COG5609	conserved protein (DUF2294)
FORC48_3099	COG2814	Major facilitator Superfamily
FORC48_3101	COG2814	Major facilitator Superfamily
FORC48_3102	COG0583	DNA-binding transcription factor activity
FORC48_3106	COG2801	Transposase and inactivated derivatives
FORC48_3107	COG5294	Protein conserved in bacteria
FORC48_3108	COG0726	polysaccharide deacetylase
FORC48_3110	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC48_3112	COG0798	PFAM Bile acid sodium symporter
FORC48_3113	COG0346	lactoylglutathione lyase activity
FORC48_3114	COG0640	Transcriptional regulator
FORC48_3116	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC48_3116	COG3320	Male sterility
FORC48_3117	COG1309	transcriptional regulator
FORC48_3121	COG0346	lactoylglutathione lyase activity
FORC48_3126	COG0745	RESPONSE REGULATOR receiver
FORC48_3127	COG5002	protein histidine kinase activity
FORC48_3127	COG3850	Histidine kinase
FORC48_3135	COG0277	FAD linked oxidase domain protein
FORC48_3137	COG1136	(ABC) transporter
FORC48_3144	COG2814	Major facilitator Superfamily
FORC48_3148	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC48_3153	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC48_3157	COG0577	efflux transmembrane transporter activity
FORC48_3161	COG5002	protein histidine kinase activity
FORC48_3161	COG3850	Histidine kinase
FORC48_3163	COG2364	Membrane
FORC48_3164	COG1846	Transcriptional regulator
FORC48_3165	COG0456	acetyltransferase
FORC48_3166	COG2808	Putative FMN-binding domain
FORC48_3167	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_3173	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC48_3181	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_3181	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_3191	COG5444	nuclease activity
FORC48_3198	COG5444	nuclease activity
FORC48_3207	COG1876	peptidase activity
FORC48_3208	COG2843	Capsule synthesis protein
FORC48_3210	COG0477	Major facilitator Superfamily
FORC48_3213	COG1846	Transcriptional regulator
FORC48_3214	COG2814	Major facilitator Superfamily
FORC48_3217	COG2031	fatty acid transporter
FORC48_3219	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_3230	COG1288	antiporter activity
FORC48_3231	COG2356	endonuclease I
FORC48_3235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC48_3239	COG1733	regulation of RNA biosynthetic process
FORC48_3240	COG0778	Nitroreductase
FORC48_3246	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_3248	COG1131	(ABC) transporter
FORC48_3253	COG1011	Hydrolase
FORC48_3259	COG0180	Tryptophanyl-tRNA synthetase
FORC48_3261	COG0628	permease
FORC48_3267	COG0500	methyltransferase
FORC48_3269	COG0477	Major facilitator Superfamily
FORC48_3275	COG1253	flavin adenine dinucleotide binding
FORC48_3276	COG0789	Transcriptional regulator
FORC48_3278	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_3284	COG0697	spore germination
FORC48_3286	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC48_3287	COG3813	Protein conserved in bacteria
FORC48_3288	COG2706	6-phosphogluconolactonase activity
FORC48_3289	COG1070	Carbohydrate kinase
FORC48_3291	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC48_3292	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC48_3293	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC48_3294	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC48_3303	COG0814	amino acid
FORC48_3308	COG2188	Transcriptional regulator
FORC48_3309	COG0673	inositol 2-dehydrogenase activity
FORC48_3313	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_3318	COG0384	phenazine biosynthesis protein PhzF
FORC48_3320	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_3323	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_3324	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_3325	COG1733	regulation of RNA biosynthetic process
FORC48_3328	COG0726	polysaccharide deacetylase
FORC48_3330	COG1191	sigma factor activity
FORC48_3334	COG1280	lysine exporter protein (LysE YggA)
FORC48_3343	COG1151	hydroxylamine reductase activity
FORC48_3346	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_3346	COG3757	hydrolase, family 25
FORC48_3353	COG2072	flavoprotein involved in K transport
FORC48_3360	COG1113	amino acid transport
FORC48_3361	COG2814	Major facilitator Superfamily
FORC48_3369	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORC48_3370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_3372	COG1247	-acetyltransferase
FORC48_3373	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_3374	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_3375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_3376	COG3739	integral membrane protein
FORC48_3380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_3384	COG0583	DNA-binding transcription factor activity
FORC48_3390	COG1193	negative regulation of DNA recombination
FORC48_3392	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC48_3393	COG1164	Oligoendopeptidase f
FORC48_3399	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_3404	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_3407	COG0640	Transcriptional regulator
FORC48_3408	COG0604	alcohol dehydrogenase
FORC48_3411	COG0457	Tetratricopeptide repeat
FORC48_3414	COG0277	FAD linked oxidase domain protein
FORC48_3419	COG1183	phosphatidylcholine synthase activity
FORC48_3422	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_3422	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_3423	COG1252	NADH dehydrogenase
FORC48_3426	COG0823	Involved in the tonB-independent uptake of proteins
FORC48_3427	COG3397	chitin binding
FORC48_3429	COG0697	spore germination
FORC48_3433	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_3435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_3438	COG0457	Tetratricopeptide repeat
FORC48_3459	COG3852	Histidine kinase
FORC48_3461	COG1285	pathogenesis
FORC48_3463	COG2514	catechol 2,3-dioxygenase activity
FORC48_3465	COG2720	vancomycin resistance protein
FORC48_3471	COG1278	Cold shock
FORC48_3473	COG0716	FMN binding
FORC48_3475	COG0494	nUDIX hydrolase
FORC48_3479	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_3481	COG0165	Argininosuccinate lyase
FORC48_3484	COG4145	pantothenate transmembrane transporter activity
FORC48_3486	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_3487	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_3489	COG1657	PFAM Prenyltransferase squalene oxidase
FORC48_3490	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FORC48_3491	COG2962	Rard protein
FORC48_3492	COG3326	Membrane
FORC48_3495	COG0489	protein tyrosine kinase activity
FORC48_3497	COG0314	molybdopterin synthase activity
FORC48_3498	COG0303	'Molybdopterin
FORC48_3499	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_3500	COG2116	formate transmembrane transporter activity
FORC48_3502	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC48_3503	COG5609	conserved protein (DUF2294)
FORC48_3504	COG2427	Protein of unknown function (DUF1641)
FORC48_3505	COG3383	formate dehydrogenase (NAD+) activity
FORC48_3507	COG0697	spore germination
FORC48_3510	COG0531	amino acid
FORC48_3517	COG2226	methyltransferase
FORC48_3518	COG4166	transmembrane transport
FORC48_3519	COG4166	transmembrane transport
FORC48_3520	COG4166	transmembrane transport
FORC48_3521	COG1301	dicarboxylic acid transport
FORC48_3522	COG1316	TRANSCRIPTIONal
FORC48_3524	COG1595	DNA-templated transcription, initiation
FORC48_3526	COG1131	(ABC) transporter
FORC48_3528	COG0673	inositol 2-dehydrogenase activity
FORC48_3529	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC48_3530	COG0187	DNA topoisomerase II activity
FORC48_3531	COG1832	CoA-binding protein
FORC48_3532	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_3533	COG0745	RESPONSE REGULATOR receiver
FORC48_3537	COG4841	protein insertion into membrane
FORC48_3538	COG0824	Thioesterase
FORC48_3544	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_3547	COG1132	(ABC) transporter
FORC48_3548	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC48_3551	COG0726	polysaccharide deacetylase
FORC48_3555	COG2211	Major facilitator Superfamily
FORC48_3557	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC48_3560	COG0183	Belongs to the thiolase family
FORC48_3561	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_3562	COG1268	BioY protein
FORC48_3563	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_3572	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_3575	COG5002	protein histidine kinase activity
FORC48_3576	COG0400	carboxylic ester hydrolase activity
FORC48_3577	COG0346	lactoylglutathione lyase activity
FORC48_3578	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_3580	COG0069	glutamate synthase activity
FORC48_3581	COG1902	pentaerythritol trinitrate reductase activity
FORC48_3582	COG1329	Transcriptional regulator
FORC48_3583	COG0010	Belongs to the arginase family
FORC48_3593	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC48_3594	COG0785	Cytochrome C biogenesis protein
FORC48_3600	COG1131	(ABC) transporter
FORC48_3603	COG0583	DNA-binding transcription factor activity
FORC48_3605	COG1346	cytolysis
FORC48_3608	COG0730	response to heat
FORC48_3613	COG1132	(ABC) transporter
FORC48_3614	COG1132	(ABC) transporter
FORC48_3620	COG3639	organic phosphonate transmembrane transporter activity
FORC48_3623	COG0737	Belongs to the 5'-nucleotidase family
FORC48_3625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC48_3629	COG1695	Transcriptional regulator
FORC48_3631	COG0739	heme binding
FORC48_3632	COG0741	lytic transglycosylase activity
FORC48_3639	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC48_3646	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_3652	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_3652	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_3652	COG1388	LysM domain
FORC48_3653	COG4824	toxin secretion phage lysis holin
FORC48_3684	COG1595	DNA-templated transcription, initiation
FORC48_3691	COG0270	DNA (cytosine-5-)-methyltransferase activity
FORC48_3693	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FORC48_3710	COG1396	sequence-specific DNA binding
FORC48_3714	COG0174	glutamine synthetase
FORC48_3715	COG0789	Transcriptional regulator
FORC48_3716	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FORC48_3717	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC48_3718	COG2860	membrane
FORC48_3720	COG0464	growth
FORC48_3726	COG1388	LysM domain
FORC48_3726	COG3584	3D domain protein
FORC48_3727	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_3727	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC48_3727	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC48_3728	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC48_3729	COG1349	DNA-binding transcription factor activity
FORC48_3730	COG1979	alcohol dehydrogenase
FORC48_3731	COG2322	membrane
FORC48_3734	COG1113	amino acid transport
FORC48_3736	COG1408	metallophosphoesterase
FORC48_3737	COG2116	formate transmembrane transporter activity
FORC48_3740	COG2217	Heavy metal translocating P-type atpase
FORC48_3741	COG2608	mercury ion transmembrane transporter activity
FORC48_3742	COG1937	Protein conserved in bacteria
FORC48_3744	COG2819	hydrolase of the alpha beta superfamily
FORC48_3745	COG1120	ATPase activity
FORC48_3746	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_3747	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_3748	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_3750	COG2169	Transcriptional regulator
FORC48_3751	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC48_3752	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC48_3754	COG2364	Membrane
FORC48_3757	COG2267	carboxylic ester hydrolase activity
FORC48_3758	COG3300	MHYT domain
FORC48_3758	COG5001	Diguanylate cyclase
FORC48_3766	COG1346	cytolysis
FORC48_3768	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_3771	COG2188	Transcriptional regulator
FORC48_3772	COG2723	6-phospho-beta-galactosidase activity
FORC48_3775	COG1404	Belongs to the peptidase S8 family
FORC48_3776	COG3773	Cell wall hydrolase
FORC48_3778	COG1368	sulfuric ester hydrolase activity
FORC48_3779	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_3784	COG4550	Control of competence regulator ComK, YlbF/YmcA
FORC48_3786	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC48_3787	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC48_3787	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC48_3789	COG2359	stage V sporulation protein S
FORC48_3790	COG1692	metallophosphoesterase
FORC48_3794	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC48_3795	COG1426	Protein conserved in bacteria
FORC48_3798	COG0300	oxidoreductase activity
FORC48_3799	COG0612	Peptidase, M16
FORC48_3800	COG0612	Peptidase, M16
FORC48_3805	COG2188	Transcriptional regulator
FORC48_3808	COG0740	serine-type endopeptidase activity
FORC48_3809	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_3811	COG0527	aspartate kinase activity
FORC48_3812	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC48_3813	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC48_3814	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_3815	COG1873	PFAM PRC-barrel domain
FORC48_3816	COG0612	Peptidase, M16
FORC48_3817	COG0726	polysaccharide deacetylase
FORC48_3820	COG0196	riboflavin kinase activity
FORC48_3823	COG1550	Protein conserved in bacteria
FORC48_3825	COG1358	cellular component organization or biogenesis
FORC48_3826	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FORC48_3827	COG0195	Participates in both transcription termination and antitermination
FORC48_3831	COG0750	zinc metalloprotease
FORC48_3833	COG4589	Belongs to the CDS family
FORC48_3843	COG4974	Belongs to the 'phage' integrase family
FORC48_3845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC48_3846	COG0758	DNA mediated transformation
FORC48_3847	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC48_3855	COG1837	Belongs to the UPF0109 family
FORC48_3857	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC48_3859	COG0552	protein localization to endoplasmic reticulum
FORC48_3860	COG1196	nuclear chromosome segregation
FORC48_3863	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_3864	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC48_3867	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC48_3868	COG1461	Dihydroxyacetone kinase
FORC48_3869	COG1302	Protein conserved in bacteria
FORC48_3872	COG1564	THIamine pyrophosphokinase
FORC48_3873	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC48_3875	COG0515	serine threonine protein kinase
FORC48_3875	COG2815	serine threonine protein kinase
FORC48_3876	COG0631	protein serine/threonine phosphatase activity
FORC48_3878	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC48_3878	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC48_3881	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC48_3882	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC48_3886	COG1561	YicC-like family, N-terminal region
FORC48_3887	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC48_3889	COG0006	proline dipeptidase activity
FORC48_3892	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC48_3904	COG0564	pseudouridine synthase activity
FORC48_3908	COG3599	regulation of cell shape
FORC48_3909	COG2302	S4 RNA-binding domain
FORC48_3910	COG0762	integral membrane protein
FORC48_3912	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC48_3914	COG1873	PFAM PRC-barrel domain
FORC48_3915	COG1191	sigma factor activity
FORC48_3916	COG1191	sigma factor activity
FORC48_3918	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC48_3919	COG0849	cell division
FORC48_3925	COG0772	Belongs to the SEDS family
FORC48_3929	COG0768	penicillin binding
FORC48_3934	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC48_3938	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC48_3940	COG3480	Lon protease (S16) C-terminal proteolytic domain
FORC48_3941	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC48_3942	COG3314	Sporulation integral membrane protein YlbJ
FORC48_3944	COG0742	ribosomal rna small subunit methyltransferase
FORC48_3947	COG3679	Belongs to the UPF0342 family
FORC48_3948	COG0406	alpha-ribazole phosphatase activity
FORC48_3951	COG2340	Cysteine-rich secretory protein family
FORC48_3954	COG3336	cytochrome c oxidase
FORC48_3962	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FORC48_3963	COG0772	Belongs to the SEDS family
FORC48_3965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FORC48_3966	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC48_3968	COG4896	Protein conserved in bacteria
FORC48_3973	COG0483	inositol monophosphate 1-phosphatase activity
FORC48_3977	COG1982	Orn Lys Arg decarboxylase major
FORC48_3987	COG0022	dehydrogenase e1 component
FORC48_3988	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_3991	COG0561	phosphatase activity
FORC48_3993	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_3994	COG0569	domain protein
FORC48_3998	COG0583	DNA-binding transcription factor activity
FORC48_3999	COG0517	IMP dehydrogenase activity
FORC48_4001	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FORC48_4003	COG4703	Protein of unknown function (DUF1797)
FORC48_4007	COG2200	EAL domain
FORC48_4008	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_4009	COG1408	metallophosphoesterase
FORC48_4018	COG2814	Major facilitator Superfamily
FORC48_4022	COG3209	COG3209 Rhs family protein
FORC48_4024	COG2205	protein histidine kinase activity
FORC48_4027	COG0436	Aminotransferase
FORC48_4028	COG1609	Transcriptional regulator
FORC48_4029	COG3833	ABC-type maltose transport systems, permease component
FORC48_4030	COG1175	transmembrane transport
FORC48_4031	COG2182	Extracellular solute-binding protein
FORC48_4033	COG0366	Alpha amylase catalytic
FORC48_4034	COG3842	ATPase activity
FORC48_4042	COG0183	Belongs to the thiolase family
FORC48_4049	COG1695	Transcriptional regulator
FORC48_4050	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_4054	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC48_4055	COG0436	Aminotransferase
FORC48_4062	COG2084	Dehydrogenase
FORC48_4064	COG2199	diguanylate cyclase activity
FORC48_4064	COG2203	Gaf domain
FORC48_4065	COG0778	Nitroreductase
FORC48_4070	COG1263	PTS System
FORC48_4070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_4070	COG2190	(PTS) system
FORC48_4071	COG3711	transcriptional antiterminator
FORC48_4075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC48_4080	COG1547	Domain of unknown function (DUF309)
FORC48_4081	COG0456	acetyltransferase
FORC48_4082	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC48_4083	COG4086	secreted protein
FORC48_4084	COG0561	phosphatase activity
FORC48_4085	COG0697	spore germination
FORC48_4088	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC48_4093	COG0733	neurotransmitter:sodium symporter activity
FORC48_4097	COG1686	Belongs to the peptidase S11 family
FORC48_4098	COG1725	Transcriptional regulator
FORC48_4099	COG1131	(ABC) transporter
FORC48_4103	COG1846	Transcriptional regulator
FORC48_4106	COG0598	Magnesium transport protein CorA
FORC48_4111	COG4974	Belongs to the 'phage' integrase family
FORC48_4113	COG0735	belongs to the Fur family
FORC48_4114	COG1300	Membrane
FORC48_4118	COG0667	Aldo Keto reductase
FORC48_4119	COG0656	L-ascorbic acid biosynthetic process
FORC48_4120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC48_4120	COG0456	acetyltransferase
FORC48_4122	COG0737	Belongs to the 5'-nucleotidase family
FORC48_4122	COG4085	toxin activity
FORC48_4122	COG1525	nuclease
FORC48_4124	COG0596	Alpha beta hydrolase
FORC48_4125	COG2056	Na+-H+ antiporter family
FORC48_4126	COG1609	Transcriptional regulator
FORC48_4127	COG0456	acetyltransferase
FORC48_4128	COG1073	alpha beta
FORC48_4131	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC48_4131	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC48_4132	COG0307	riboflavin synthase, alpha
FORC48_4138	COG2226	methyltransferase
FORC48_4138	COG1073	alpha beta
FORC48_4141	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_4144	COG0737	Belongs to the 5'-nucleotidase family
FORC48_4146	COG1522	sequence-specific DNA binding
FORC48_4155	COG0300	oxidoreductase activity
FORC48_4156	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_4157	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_4158	COG1760	l-serine dehydratase
FORC48_4159	COG1760	l-serine dehydratase
FORC48_4165	COG1285	pathogenesis
FORC48_4167	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC48_4168	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_4171	COG1376	ErfK ybiS ycfS ynhG family protein
FORC48_4172	COG4129	membrane
FORC48_4173	COG1126	abc transporter atp-binding protein
FORC48_4174	COG0765	amino acid transport
FORC48_4175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_4179	COG2323	membrane
FORC48_4180	COG0772	Belongs to the SEDS family
FORC48_4181	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_4182	COG0022	dehydrogenase e1 component
FORC48_4183	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_4184	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_4186	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC48_4187	COG0280	phosphate acetyltransferase
FORC48_4188	COG3290	protein histidine kinase activity
FORC48_4188	COG3829	transcription factor binding
FORC48_4190	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_4191	COG3093	addiction module antidote protein HigA
FORC48_4194	COG0750	zinc metalloprotease
FORC48_4195	COG0497	DNA recombination
FORC48_4197	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FORC48_4199	COG0142	geranyltranstransferase activity
FORC48_4204	COG1302	Protein conserved in bacteria
FORC48_4205	COG0439	Biotin carboxylase
FORC48_4206	COG0511	ligase activity, forming carbon-carbon bonds
FORC48_4215	COG3854	ATPases associated with a variety of cellular activities
FORC48_4220	COG0006	proline dipeptidase activity
FORC48_4223	COG3872	metal-dependent enzyme
FORC48_4225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC48_4228	COG1695	Transcriptional regulator
FORC48_4232	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_4234	COG1609	Transcriptional regulator
FORC48_4236	COG2076	Multidrug Resistance protein
FORC48_4237	COG2076	Multidrug Resistance protein
FORC48_4244	COG1131	(ABC) transporter
FORC48_4245	COG1725	Transcriptional regulator
FORC48_4252	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_4266	COG1459	type II secretion system
FORC48_4267	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC48_4278	COG0646	methionine synthase
FORC48_4278	COG1410	methionine synthase
FORC48_4279	COG0646	methionine synthase
FORC48_4279	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC48_4281	COG0626	cystathionine gamma-synthase activity
FORC48_4282	COG0626	cystathionine gamma-synthase activity
FORC48_4283	COG0626	cystathionine gamma-synthase activity
FORC48_4287	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_4289	COG1940	carbohydrate kinase activity
FORC48_4290	COG4483	Protein conserved in bacteria
FORC48_4291	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC48_4293	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_4294	COG0704	Plays a role in the regulation of phosphate uptake
FORC48_4296	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_4297	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_4298	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC48_4300	COG0477	Major facilitator Superfamily
FORC48_4301	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC48_4306	COG0735	belongs to the Fur family
FORC48_4307	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC48_4308	COG1121	(ABC) transporter
FORC48_4309	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_4315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC48_4316	COG2384	SAM-dependent methyltransferase
FORC48_4318	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC48_4319	COG0358	DNA primase activity
FORC48_4323	COG0517	IMP dehydrogenase activity
FORC48_4326	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC48_4327	COG0295	cytidine deaminase activity
FORC48_4328	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC48_4330	COG1480	7TM receptor with intracellular HD hydrolase
FORC48_4331	COG1702	phosphate starvation-inducible protein PhoH
FORC48_4335	COG1610	YqeY-like protein
FORC48_4338	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC48_4339	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC48_4345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC48_4346	COG1733	regulation of RNA biosynthetic process
FORC48_4351	COG1466	dna polymerase III delta subunit
FORC48_4354	COG2333	competence protein COMEC
FORC48_4354	COG0658	competence protein
FORC48_4355	COG2131	deaminase
FORC48_4356	COG1555	photosystem II stabilization
FORC48_4356	COG1596	polysaccharide export
FORC48_4357	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_4358	COG2226	methyltransferase
FORC48_4359	COG0799	negative regulation of ribosome biogenesis
FORC48_4360	COG1713	HD superfamily hydrolase involved in NAD metabolism
FORC48_4362	COG1534	Rna-binding protein
FORC48_4364	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC48_4365	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FORC48_4368	COG1191	sigma factor activity
FORC48_4371	COG1595	DNA-templated transcription, initiation
FORC48_4374	COG0778	Nitroreductase
FORC48_4375	COG2357	RelA SpoT domain protein
FORC48_4377	COG1785	Belongs to the alkaline phosphatase family
FORC48_4379	COG2267	carboxylic ester hydrolase activity
FORC48_4386	COG1404	Belongs to the peptidase S8 family
FORC48_4388	COG3186	Phenylalanine-4-hydroxylase
FORC48_4390	COG2514	catechol 2,3-dioxygenase activity
FORC48_4391	COG2259	Doxx family
FORC48_4399	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_4401	COG1454	alcohol dehydrogenase
FORC48_4401	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_4402	COG0626	cystathionine gamma-synthase activity
FORC48_4403	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_4415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC48_4421	COG0628	permease
FORC48_4425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC48_4428	COG1104	cysteine desulfurase activity
FORC48_4429	COG1959	2 iron, 2 sulfur cluster binding
FORC48_4430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC48_4432	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC48_4437	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC48_4439	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORC48_4439	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC48_4440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC48_4441	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC48_4441	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC48_4443	COG2244	polysaccharide biosynthetic process
FORC48_4444	COG2323	membrane
FORC48_4446	COG1862	Preprotein translocase
FORC48_4452	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC48_4458	COG0157	Belongs to the NadC ModD family
FORC48_4459	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC48_4460	COG1104	cysteine desulfurase activity
FORC48_4461	COG1827	regulation of RNA biosynthetic process
FORC48_4462	COG2258	MOSC domain
FORC48_4463	COG0077	Prephenate dehydratase
FORC48_4464	COG0577	efflux transmembrane transporter activity
FORC48_4465	COG0577	efflux transmembrane transporter activity
FORC48_4466	COG1136	(ABC) transporter
FORC48_4467	COG5002	protein histidine kinase activity
FORC48_4468	COG0745	RESPONSE REGULATOR receiver
FORC48_4470	COG3290	protein histidine kinase activity
FORC48_4472	COG2868	ribosomal protein
FORC48_4474	COG1530	ribonuclease E activity
FORC48_4475	COG1994	Peptidase M50
FORC48_4476	COG0739	heme binding
FORC48_4477	COG2894	cell division
FORC48_4480	COG1792	Involved in formation and maintenance of cell shape
FORC48_4481	COG1077	Cell shape determining protein MreB Mrl
FORC48_4485	COG0285	dihydrofolate synthase activity
FORC48_4488	COG1388	LysM domain
FORC48_4490	COG0113	porphobilinogen synthase activity
FORC48_4491	COG1587	Uroporphyrinogen-III synthase
FORC48_4493	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC48_4495	COG1846	Transcriptional regulator
FORC48_4496	COG1764	response to oxidative stress
FORC48_4499	COG0470	DNA polymerase III
FORC48_4499	COG1067	ATP-dependent peptidase activity
FORC48_4508	COG0622	Phosphoesterase
FORC48_4511	COG5401	PFAM Sporulation and spore germination
FORC48_4516	COG1309	transcriptional regulator
FORC48_4518	COG2197	response regulator
FORC48_4519	COG2233	PERMEase
FORC48_4521	COG0402	S-adenosylhomocysteine deaminase activity
FORC48_4522	COG1983	PspC domain protein
FORC48_4523	COG1396	sequence-specific DNA binding
FORC48_4524	COG0697	spore germination
FORC48_4526	COG1959	2 iron, 2 sulfur cluster binding
FORC48_4527	COG1668	transmembrane transport
FORC48_4528	COG4152	abc transporter atp-binding protein
FORC48_4529	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FORC48_4530	COG1360	Flagellar Motor Protein
FORC48_4531	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC48_4532	COG1876	peptidase activity
FORC48_4533	COG0824	Thioesterase
FORC48_4534	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC48_4535	COG1053	succinate dehydrogenase
FORC48_4536	COG2009	succinate dehydrogenase
FORC48_4537	COG1719	4-vinyl reductase, 4VR
FORC48_4539	COG3118	belongs to the thioredoxin family
FORC48_4540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORC48_4541	COG2086	electron transfer activity
FORC48_4542	COG1024	Enoyl-CoA hydratase
FORC48_4543	COG1309	transcriptional regulator
FORC48_4544	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_4550	COG2318	DinB family
FORC48_4556	COG1131	(ABC) transporter
FORC48_4557	COG2205	protein histidine kinase activity
FORC48_4558	COG0745	RESPONSE REGULATOR receiver
FORC48_4560	COG4895	conserved protein (DUF2196)
FORC48_4561	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC48_4563	COG4509	Sortase family
FORC48_4564	COG1120	ATPase activity
FORC48_4567	COG5386	Cell surface protein
FORC48_4569	COG5386	Cell surface protein
FORC48_4571	COG1114	Component of the transport system for branched-chain amino acids
FORC48_4572	COG1187	pseudouridine synthase activity
FORC48_4575	COG1796	DNA polymerase
FORC48_4575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC48_4576	COG1286	toxin biosynthetic process
FORC48_4585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC48_4587	COG1418	mRNA catabolic process
FORC48_4591	COG2814	Major facilitator Superfamily
FORC48_4592	COG1566	PFAM secretion protein HlyD family protein
FORC48_4593	COG1309	transcriptional regulator
FORC48_4594	COG1363	Peptidase, m42
FORC48_4599	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC48_4602	COG1484	DNA-dependent DNA replication
FORC48_4603	COG3611	Membrane attachment protein
FORC48_4605	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC48_4607	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC48_4609	COG1971	Probably functions as a manganese efflux pump
FORC48_4611	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_4611	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_4612	COG5002	protein histidine kinase activity
FORC48_4613	COG0745	RESPONSE REGULATOR receiver
FORC48_4618	COG0538	isocitrate dehydrogenase activity
FORC48_4619	COG0372	Belongs to the citrate synthase family
FORC48_4621	COG0628	permease
FORC48_4622	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC48_4627	COG1725	Transcriptional regulator
FORC48_4628	COG0281	malic enzyme
FORC48_4629	COG0587	DNA-directed DNA polymerase activity
FORC48_4632	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC48_4635	COG4109	DRTGG domain
FORC48_4638	COG0006	proline dipeptidase activity
FORC48_4644	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_4645	COG0662	Cupin 2, conserved barrel domain protein
FORC48_4648	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_4649	COG0589	response to stress
FORC48_4658	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_4663	COG0827	DNA restriction-modification system
FORC48_4664	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC48_4665	COG3874	Sporulation protein YtfJ
FORC48_4668	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FORC48_4670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_4673	COG1104	cysteine desulfurase activity
FORC48_4675	COG0583	DNA-binding transcription factor activity
FORC48_4676	COG0697	spore germination
FORC48_4677	COG1309	transcriptional regulator
FORC48_4678	COG1956	GAF domain-containing protein
FORC48_4679	COG0626	cystathionine gamma-synthase activity
FORC48_4689	COG0110	maltose O-acetyltransferase activity
FORC48_4690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_4691	COG0454	-acetyltransferase
FORC48_4692	COG0517	IMP dehydrogenase activity
FORC48_4693	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC48_4696	COG0745	RESPONSE REGULATOR receiver
FORC48_4697	COG5002	protein histidine kinase activity
FORC48_4698	COG0666	response to abiotic stimulus
FORC48_4705	COG1609	Transcriptional regulator
FORC48_4706	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC48_4706	COG1605	Chorismate mutase
FORC48_4707	COG4851	CamS sex pheromone cAM373 precursor
FORC48_4708	COG3118	belongs to the thioredoxin family
FORC48_4710	COG2309	aminopeptidase activity
FORC48_4713	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_4716	COG1674	ftsk spoiiie
FORC48_4717	COG1388	LysM domain
FORC48_4717	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_4719	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC48_4721	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_4722	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC48_4723	COG1363	Peptidase, m42
FORC48_4725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_4728	COG0510	thiamine kinase activity
FORC48_4729	COG1523	belongs to the glycosyl hydrolase 13 family
FORC48_4731	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_4732	COG1349	DNA-binding transcription factor activity
FORC48_4733	COG1187	pseudouridine synthase activity
FORC48_4734	COG2244	polysaccharide biosynthetic process
FORC48_4735	COG2081	HI0933 family
FORC48_4736	COG2814	Major facilitator Superfamily
FORC48_4738	COG3832	glyoxalase III activity
FORC48_4742	COG1329	Transcriptional regulator
FORC48_4747	COG0314	molybdopterin synthase activity
FORC48_4748	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC48_4749	COG0303	'Molybdopterin
FORC48_4751	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_4752	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC48_4756	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_4758	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC48_4767	COG2814	Major facilitator Superfamily
FORC48_4768	COG0475	glutathione-regulated potassium exporter activity
FORC48_4769	COG0490	domain, Protein
FORC48_4770	COG0582	viral genome integration into host DNA
FORC48_4772	COG1136	(ABC) transporter
FORC48_4776	COG1242	4 iron, 4 sulfur cluster binding
FORC48_4777	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FORC48_4778	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_4781	COG2267	carboxylic ester hydrolase activity
FORC48_4782	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC48_4783	COG0671	phosphoesterase, PA-phosphatase related
FORC48_4784	COG0438	transferase activity, transferring glycosyl groups
FORC48_4788	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_4799	COG5002	protein histidine kinase activity
FORC48_4800	COG3852	Histidine kinase
FORC48_4803	COG2267	carboxylic ester hydrolase activity
FORC48_4809	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_4810	COG1116	anion transmembrane transporter activity
FORC48_4811	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_4816	COG0494	nUDIX hydrolase
FORC48_4825	COG0288	reversible hydration of carbon dioxide
FORC48_4826	COG1271	oxidase subunit
FORC48_4827	COG1294	oxidase, subunit
FORC48_4830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_4835	COG1842	Phage shock protein A
FORC48_4841	COG5002	protein histidine kinase activity
FORC48_4842	COG0745	RESPONSE REGULATOR receiver
FORC48_4848	COG1597	lipid kinase activity
FORC48_4856	COG0586	Pfam SNARE associated Golgi protein
FORC48_4858	COG0577	efflux transmembrane transporter activity
FORC48_4859	COG1136	(ABC) transporter
FORC48_4860	COG3708	Transcriptional regulator
FORC48_4860	COG2207	Transcriptional regulator
FORC48_4864	COG5658	integral membrane protein
FORC48_4865	COG0640	Transcriptional regulator
FORC48_4866	COG0745	RESPONSE REGULATOR receiver
FORC48_4867	COG2205	protein histidine kinase activity
FORC48_4868	COG0577	efflux transmembrane transporter activity
FORC48_4869	COG0577	efflux transmembrane transporter activity
FORC48_4870	COG1136	(ABC) transporter
FORC48_4871	COG0577	efflux transmembrane transporter activity
FORC48_4880	COG3964	amidohydrolase
FORC48_4884	COG4948	Mandelate Racemase Muconate Lactonizing
FORC48_4886	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC48_4887	COG0596	Alpha beta hydrolase
FORC48_4889	COG1169	isochorismate synthase
FORC48_4891	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC48_4892	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC48_4893	COG1278	Cold shock
FORC48_4898	COG0058	SHG alpha-glucan phosphorylase activity
FORC48_4900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC48_4904	COG1404	Belongs to the peptidase S8 family
FORC48_4905	COG0039	L-malate dehydrogenase activity
FORC48_4906	COG1285	pathogenesis
FORC48_4907	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC48_4910	COG2155	Conserved Protein
FORC48_4911	COG1098	S1 RNA binding domain
FORC48_4912	COG0436	Aminotransferase
FORC48_4913	COG1522	sequence-specific DNA binding
FORC48_4914	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_4915	COG2267	carboxylic ester hydrolase activity
FORC48_4917	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC48_4921	COG5018	Exonuclease
FORC48_4922	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_4925	COG0423	glycine-tRNA ligase activity
FORC48_4926	COG2050	protein possibly involved in aromatic compounds catabolism
FORC48_4928	COG1268	BioY protein
FORC48_4930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC48_4931	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC48_4935	COG2076	Multidrug Resistance protein
FORC48_4936	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC48_4938	COG3584	3D domain protein
FORC48_4941	COG1252	NADH dehydrogenase
FORC48_4945	COG3708	Transcriptional regulator
FORC48_4948	COG1683	Conserved Protein
FORC48_4953	COG0316	Belongs to the HesB IscA family
FORC48_4956	COG1252	NADH dehydrogenase
FORC48_4958	COG2274	protein secretion by the type I secretion system
FORC48_4959	COG0390	transport system, permease component
FORC48_4960	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC48_4965	COG4837	Protein of unknown function (DUF1462)
FORC48_4966	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC48_4968	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC48_4969	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC48_4973	COG1358	cellular component organization or biogenesis
FORC48_4976	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_4977	COG0647	UMP catabolic process
FORC48_4979	COG2445	Protein of unknown function DUF86
FORC48_4980	COG1494	fructose-1,6-bisphosphatase
FORC48_4984	COG4470	Protein conserved in bacteria
FORC48_4986	COG0789	Transcriptional regulator
FORC48_4987	COG4377	Putative membrane peptidase family (DUF2324)
FORC48_4992	COG0739	heme binding
FORC48_4994	COG3377	Domain of unknown function (DUF1805)
FORC48_4995	COG0737	Belongs to the 5'-nucleotidase family
FORC48_4996	COG0719	Fe-S assembly protein
FORC48_4997	COG0822	iron-sulfur transferase activity
FORC48_4998	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC48_4999	COG0719	Fe-S assembly protein
FORC48_5000	COG0396	ATPase activity
FORC48_5001	COG1464	Belongs to the NlpA lipoprotein family
FORC48_5002	COG1464	Belongs to the NlpA lipoprotein family
FORC48_5003	COG2011	ABC-type metal ion transport system permease component
FORC48_5006	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_5007	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FORC48_5010	COG1393	Belongs to the ArsC family
FORC48_5021	COG1309	transcriptional regulator
FORC48_5022	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_5023	COG1960	acyl-CoA dehydrogenase activity
FORC48_5025	COG0183	Belongs to the thiolase family
FORC48_5026	COG1024	Enoyl-CoA hydratase
FORC48_5026	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC48_5028	COG1686	Belongs to the peptidase S11 family
FORC48_5031	COG0011	TIGRFAM Protein of
FORC48_5032	COG0840	transmembrane signaling receptor activity
FORC48_5035	COG2814	Major facilitator Superfamily
FORC48_5036	COG0531	amino acid
FORC48_5042	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_5050	COG0586	Pfam SNARE associated Golgi protein
FORC48_5052	COG1376	ErfK ybiS ycfS ynhG family protein
FORC48_5053	COG0745	RESPONSE REGULATOR receiver
FORC48_5054	COG5002	protein histidine kinase activity
FORC48_5060	COG0840	transmembrane signaling receptor activity
FORC48_5061	COG2151	metal-sulfur cluster biosynthetic enzyme
FORC48_5062	COG3227	Zinc metalloprotease (Elastase)
FORC48_5063	COG1741	Belongs to the pirin family
FORC48_5066	COG0475	glutathione-regulated potassium exporter activity
FORC48_5067	COG0490	domain, Protein
FORC48_5069	COG1115	amino acid carrier protein
FORC48_5071	COG0783	Belongs to the Dps family
FORC48_5074	COG1611	Belongs to the LOG family
FORC48_5076	COG1528	Iron-storage protein
FORC48_5078	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_5079	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_5080	COG1115	amino acid carrier protein
FORC48_5081	COG1115	amino acid carrier protein
FORC48_5082	COG2910	NAD(P)H-binding
FORC48_5085	COG0656	L-ascorbic acid biosynthetic process
FORC48_5086	COG2814	Major facilitator Superfamily
FORC48_5087	COG1733	regulation of RNA biosynthetic process
FORC48_5089	COG1252	NADH dehydrogenase
FORC48_5100	COG0488	(ABC) transporter
FORC48_5101	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_5102	COG3223	Belongs to the PsiE family
FORC48_5115	COG0557	exoribonuclease II activity
FORC48_5116	COG1647	Serine aminopeptidase, S33
FORC48_5117	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC48_5118	COG1346	cytolysis
FORC48_5125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC48_5128	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC48_5129	COG1668	transmembrane transport
FORC48_5130	COG4152	abc transporter atp-binding protein
FORC48_5132	COG4585	Histidine kinase
FORC48_5137	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC48_5140	COG2323	membrane
FORC48_5142	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_5144	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC48_5146	COG1051	belongs to the nudix hydrolase family
FORC48_5148	COG0492	ferredoxin-NADP+ reductase activity
FORC48_5149	COG0457	Tetratricopeptide repeat
FORC48_5150	COG0110	maltose O-acetyltransferase activity
FORC48_5154	COG1950	PFAM Membrane protein of
FORC48_5156	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC48_5157	COG0556	nucleotide-excision repair
FORC48_5160	COG0789	Transcriptional regulator
FORC48_5164	COG0583	DNA-binding transcription factor activity
FORC48_5166	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC48_5169	COG1132	(ABC) transporter
FORC48_5170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_5171	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_5171	COG0793	Belongs to the peptidase S41A family
FORC48_5172	COG2177	Part of the ABC transporter FtsEX involved in
FORC48_5173	COG2884	Cell division ATP-binding protein ftsE
FORC48_5178	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC48_5180	COG1278	Cold shock
FORC48_5181	COG1040	competence protein
FORC48_5182	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FORC48_5184	COG0791	NLP P60 protein
FORC48_5184	COG1388	LysM domain
FORC48_5185	COG1733	regulation of RNA biosynthetic process
FORC48_5186	COG1307	EDD domain protein, DegV family
FORC48_5188	COG1739	Uncharacterized protein family UPF0029
FORC48_5189	COG1316	TRANSCRIPTIONal
FORC48_5190	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC48_5191	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC48_5192	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC48_5194	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FORC48_5194	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC48_5198	COG1486	melibiose metabolic process
FORC48_5199	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_5200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_5204	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_5206	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_5207	COG1301	dicarboxylic acid transport
FORC48_5210	COG1511	domain protein
FORC48_5211	COG0583	DNA-binding transcription factor activity
FORC48_5212	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC48_5214	COG1271	oxidase subunit
FORC48_5215	COG1294	oxidase, subunit
FORC48_5216	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_5221	COG1620	l-lactate permease
FORC48_5223	COG2389	metal-binding protein
FORC48_5225	COG1368	sulfuric ester hydrolase activity
FORC48_5230	COG0791	NLP P60 protein
FORC48_5230	COG1388	LysM domain
FORC48_5232	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_5234	COG1215	transferase activity, transferring glycosyl groups
FORC48_5236	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_5237	COG1388	LysM domain
FORC48_5237	COG3584	3D domain protein
FORC48_5242	COG4715	Zinc finger, swim domain protein
FORC48_5243	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_5249	COG1191	sigma factor activity
FORC48_5251	COG0577	efflux transmembrane transporter activity
FORC48_5252	COG1136	(ABC) transporter
FORC48_5256	COG2271	Major facilitator Superfamily
FORC48_5259	COG5002	protein histidine kinase activity
FORC48_5260	COG0745	RESPONSE REGULATOR receiver
FORC48_5264	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC48_5270	COG0438	transferase activity, transferring glycosyl groups
FORC48_5273	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_5275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC48_5276	COG1086	Polysaccharide biosynthesis protein
FORC48_5277	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC48_5278	COG4464	protein tyrosine phosphatase activity
FORC48_5279	COG0489	protein tyrosine kinase activity
FORC48_5280	COG3944	biosynthesis protein
FORC48_5281	COG0489	protein tyrosine kinase activity
FORC48_5284	COG1609	Transcriptional regulator
FORC48_5286	COG0739	heme binding
FORC48_5289	COG3279	Response regulator of the LytR AlgR family
FORC48_5290	COG2385	sporulation resulting in formation of a cellular spore
FORC48_5293	COG4836	Membrane
FORC48_5294	COG1007	ATP synthesis coupled electron transport
FORC48_5295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC48_5296	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC48_5298	COG0839	Belongs to the complex I subunit 6 family
FORC48_5302	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC48_5305	COG3300	MHYT domain
FORC48_5305	COG5001	Diguanylate cyclase
FORC48_5316	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC48_5323	COG0698	ribose 5-phosphate isomerase
FORC48_5326	COG2259	Doxx family
FORC48_5327	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC48_5331	COG0009	L-threonylcarbamoyladenylate synthase
FORC48_5338	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC48_5339	COG1494	fructose-1,6-bisphosphatase
FORC48_5344	COG4821	SIS domain
FORC48_5346	COG3343	RNA polymerase activity
FORC48_5348	COG1960	acyl-CoA dehydrogenase activity
FORC48_5349	COG1960	acyl-CoA dehydrogenase activity
FORC48_5350	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC48_5351	COG0183	Belongs to the thiolase family
FORC48_5352	COG0247	lactate metabolic process
FORC48_5352	COG2181	nitrate reductase activity
FORC48_5353	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_5355	COG5001	Diguanylate cyclase
FORC48_5355	COG3300	MHYT domain
FORC48_5358	COG3227	Zinc metalloprotease (Elastase)
FORC48_5359	COG2197	response regulator
FORC48_5360	COG4585	Histidine kinase
FORC48_5361	COG0842	Transport permease protein
FORC48_5362	COG1131	(ABC) transporter
FORC48_5363	COG0024	Methionine aminopeptidase
FORC48_5365	COG2234	aminopeptidase activity
FORC48_5369	COG1595	DNA-templated transcription, initiation
FORC48_5371	COG4506	Protein conserved in bacteria
FORC48_5372	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC48_5377	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC48_5378	COG2814	Major facilitator Superfamily
FORC48_5379	COG0789	Transcriptional regulator
FORC48_5381	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_5382	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_5384	COG1994	Peptidase M50
FORC48_5387	COG1078	dGTPase activity
FORC48_5388	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_5389	COG1120	ATPase activity
FORC48_5390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_5391	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_5395	COG0280	phosphate acetyltransferase
FORC48_5398	COG3773	Cell wall hydrolase
FORC48_5400	COG2363	Small membrane protein
FORC48_5402	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC48_5403	COG2233	PERMEase
FORC48_5404	COG0561	phosphatase activity
FORC48_5405	COG2814	Major facilitator Superfamily
FORC48_5407	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC48_5408	COG1131	(ABC) transporter
FORC48_5409	COG2755	lipolytic protein G-D-S-L family
FORC48_5410	COG1609	Transcriptional regulator
FORC48_5412	COG0460	homoserine dehydrogenase
FORC48_5416	COG1011	Hydrolase
FORC48_5417	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_5419	COG2197	response regulator
FORC48_5420	COG4585	Histidine kinase
FORC48_5420	COG2203	Gaf domain
FORC48_5421	COG0351	phosphomethylpyrimidine kinase
FORC48_5422	COG3706	GGDEF domain
FORC48_5423	COG2879	small protein
FORC48_5424	COG1966	Carbon starvation protein
FORC48_5425	COG3279	Response regulator of the LytR AlgR family
FORC48_5426	COG0477	Major facilitator Superfamily
FORC48_5428	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC48_5429	COG0438	transferase activity, transferring glycosyl groups
FORC48_5432	COG0840	transmembrane signaling receptor activity
FORC48_5434	COG1607	acyl-coa hydrolase
FORC48_5436	COG1216	Glycosyl transferase, family 2
FORC48_5438	COG1216	Glycosyl transferase, family 2
FORC48_5440	COG4485	Bacterial membrane protein, YfhO
FORC48_5441	COG0463	Glycosyl transferase, family 2
FORC48_5442	COG0488	(ABC) transporter
FORC48_5443	COG1309	transcriptional regulator
FORC48_5444	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC48_5445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_5445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_5446	COG0628	permease
FORC48_5450	COG3275	phosphorelay sensor kinase activity
FORC48_5451	COG2814	Major facilitator Superfamily
FORC48_5452	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_5453	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FORC48_5457	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC48_5458	COG1272	protein, Hemolysin III
FORC48_5462	COG1164	Oligoendopeptidase f
FORC48_5464	COG5002	protein histidine kinase activity
FORC48_5467	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_5468	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC48_5469	COG4853	Protein conserved in bacteria
FORC48_5471	COG5002	protein histidine kinase activity
FORC48_5472	COG0745	RESPONSE REGULATOR receiver
FORC48_5474	COG0305	Participates in initiation and elongation during chromosome replication
FORC48_5476	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FORC48_5477	COG4241	membrane
FORC48_5481	COG0012	GTP binding
FORC48_5482	COG4481	Protein conserved in bacteria
FORC48_5483	COG0668	transmembrane transport
FORC48_5485	COG1475	DNA binding
FORC48_5486	COG1192	Involved in chromosome partitioning
FORC48_5491	COG1847	R3H domain protein
FORC48_t098	COG0544	peptidyl-prolyl cis-trans isomerase activity