locus-tag	class	description
L2I54_00010	COG0592	DNA-directed DNA polymerase activity
L2I54_00015	COG2501	S4 domain
L2I54_00025	COG0187	DNA topoisomerase II activity
L2I54_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L2I54_00065	COG0516	GMP reductase activity
L2I54_00065	COG0517	IMP dehydrogenase activity
L2I54_00070	COG1686	Belongs to the peptidase S11 family
L2I54_00100	COG1428	Deoxynucleoside kinase
L2I54_00105	COG1428	Deoxynucleoside kinase
L2I54_00110	COG1335	isochorismatase
L2I54_00115	COG0590	tRNA wobble adenosine to inosine editing
L2I54_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2I54_00180	COG1982	Orn Lys Arg decarboxylase major
L2I54_00190	COG0470	DNA polymerase III
L2I54_00195	COG1774	PSP1 C-terminal conserved region
L2I54_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L2I54_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L2I54_00220	COG2002	toxin-antitoxin pair type II binding
L2I54_00230	COG0084	hydrolase, TatD family'
L2I54_00250	COG4466	Protein conserved in bacteria
L2I54_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L2I54_00270	COG0251	oxidation-reduction process
L2I54_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2I54_00305	COG2002	toxin-antitoxin pair type II binding
L2I54_00310	COG2244	polysaccharide biosynthetic process
L2I54_00315	COG3956	TIGRFAM MazG family protein
L2I54_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2I54_00340	COG1098	S1 RNA binding domain
L2I54_00355	COG2208	phosphoserine phosphatase activity
L2I54_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L2I54_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2I54_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2I54_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L2I54_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
L2I54_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2I54_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2I54_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L2I54_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2I54_00420	COG1396	sequence-specific DNA binding
L2I54_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2I54_00515	COG3880	PFAM UvrB UvrC protein
L2I54_00525	COG0542	response to heat
L2I54_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L2I54_00540	COG4956	integral membrane protein (PIN domain superfamily)
L2I54_00560	COG1045	serine acetyltransferase
L2I54_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2I54_00580	COG3688	RNA-binding protein containing a PIN domain
L2I54_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L2I54_00600	COG0250	Participates in transcription elongation, termination and antitermination
L2I54_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L2I54_00625	COG2813	Specifically methylates the guanine in position
L2I54_00640	COG1358	cellular component organization or biogenesis
L2I54_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L2I54_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
L2I54_00770	COG0201	protein transport
L2I54_00780	COG0024	Methionine aminopeptidase
L2I54_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L2I54_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L2I54_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
L2I54_00855	COG0489	protein tyrosine kinase activity
L2I54_00865	COG2194	sulfuric ester hydrolase activity
L2I54_00870	COG0726	polysaccharide deacetylase
L2I54_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L2I54_00955	COG4856	YbbR-like protein
L2I54_00995	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_01000	COG2011	ABC-type metal ion transport system permease component
L2I54_01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2I54_01010	COG1464	Belongs to the NlpA lipoprotein family
L2I54_01015	COG0604	alcohol dehydrogenase
L2I54_01025	COG0277	FAD linked oxidase domain protein
L2I54_01030	COG2271	Major facilitator Superfamily
L2I54_01040	COG2814	Major facilitator Superfamily
L2I54_01055	COG2207	Transcriptional regulator
L2I54_01070	COG4166	transmembrane transport
L2I54_01075	COG4166	transmembrane transport
L2I54_01080	COG0656	L-ascorbic acid biosynthetic process
L2I54_01095	COG4149	molybdate abc transporter
L2I54_01100	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2I54_01105	COG1910	domain protein
L2I54_01120	COG0697	spore germination
L2I54_01135	COG0204	Acyl-transferase
L2I54_01145	COG1609	Transcriptional regulator
L2I54_01155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_01170	COG5298	Protein conserved in bacteria
L2I54_01195	COG0488	(ABC) transporter
L2I54_01205	COG0747	negative chemotaxis
L2I54_01210	COG0601	transmembrane transport
L2I54_01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2I54_01220	COG0444	Belongs to the ABC transporter superfamily
L2I54_01225	COG4608	Belongs to the ABC transporter superfamily
L2I54_01230	COG0561	phosphatase activity
L2I54_01250	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L2I54_01255	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2I54_01265	COG0531	amino acid
L2I54_01270	COG2814	Major facilitator Superfamily
L2I54_01280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2I54_01290	COG4294	response to UV
L2I54_01295	COG0705	Rhomboid family
L2I54_01305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2I54_01310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2I54_01315	COG0864	Transcriptional regulator
L2I54_01320	COG2337	Toxic component of a toxin-antitoxin (TA) module
L2I54_01325	COG2183	response to ionizing radiation
L2I54_01425	COG0802	atpase or kinase
L2I54_01430	COG1214	PFAM Peptidase M22, glycoprotease
L2I54_01435	COG0456	acetyltransferase
L2I54_01445	COG0488	(ABC) transporter
L2I54_01460	COG1266	CAAX protease self-immunity
L2I54_01480	COG2252	PERMEase
L2I54_01490	COG5002	protein histidine kinase activity
L2I54_01515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2I54_01555	COG2205	protein histidine kinase activity
L2I54_01560	COG0745	RESPONSE REGULATOR receiver
L2I54_01600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2I54_01610	COG1215	transferase activity, transferring glycosyl groups
L2I54_01630	COG0697	spore germination
L2I54_01665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L2I54_01670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2I54_01675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2I54_01685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2I54_01700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L2I54_01710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2I54_01720	COG0151	Belongs to the GarS family
L2I54_01745	COG0210	DNA helicase
L2I54_01755	COG4851	CamS sex pheromone cAM373 precursor
L2I54_01770	COG1335	isochorismatase
L2I54_01780	COG2011	ABC-type metal ion transport system permease component
L2I54_01785	COG1464	Belongs to the NlpA lipoprotein family
L2I54_01800	COG0003	Pfam Anion-transporting ATPase
L2I54_01805	COG1846	Transcriptional regulator
L2I54_01810	COG4682	membrane
L2I54_01830	COG1597	lipid kinase activity
L2I54_01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2I54_01850	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_01855	COG2076	Multidrug Resistance protein
L2I54_01865	COG2309	aminopeptidase activity
L2I54_01885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_01895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2I54_01900	COG4807	Protein conserved in bacteria
L2I54_01925	COG1757	Na H antiporter
L2I54_01930	COG1473	amidohydrolase
L2I54_01945	COG0450	alkyl hydroperoxide reductase
L2I54_01965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_01970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_01975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_01980	COG0492	ferredoxin-NADP+ reductase activity
L2I54_01990	COG0166	Belongs to the GPI family
L2I54_02015	COG5002	protein histidine kinase activity
L2I54_02035	COG3541	Predicted nucleotidyltransferase
L2I54_02045	COG2814	Major facilitator Superfamily
L2I54_02050	COG0723	plastoquinol--plastocyanin reductase activity
L2I54_02050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2I54_02060	COG0765	amino acid transport
L2I54_02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2I54_02070	COG1126	abc transporter atp-binding protein
L2I54_02075	COG0840	transmembrane signaling receptor activity
L2I54_02100	COG0549	Belongs to the carbamate kinase family
L2I54_02105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2I54_02115	COG0277	FAD linked oxidase domain protein
L2I54_02120	COG0366	Alpha amylase catalytic
L2I54_02125	COG2190	(PTS) system
L2I54_02125	COG1263	PTS System
L2I54_02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_02155	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
L2I54_02175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2I54_02180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2I54_02185	COG1116	anion transmembrane transporter activity
L2I54_02235	COG2270	Major facilitator Superfamily
L2I54_02265	COG2310	stress, protein
L2I54_02270	COG2310	stress, protein
L2I54_02275	COG2310	stress, protein
L2I54_02280	COG0861	Integral membrane protein TerC family
L2I54_02290	COG3853	Toxic anion resistance protein (TelA)
L2I54_02305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2I54_02315	COG1295	ribonuclease BN
L2I54_02320	COG2217	Heavy metal translocating P-type atpase
L2I54_02325	COG0697	spore germination
L2I54_02345	COG0586	Pfam SNARE associated Golgi protein
L2I54_02360	COG3871	stress protein (general stress protein 26)
L2I54_02365	COG0387	Pfam Sodium calcium exchanger
L2I54_02375	COG0535	radical SAM domain protein
L2I54_02395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L2I54_02400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L2I54_02415	COG3829	transcription factor binding
L2I54_02425	COG0833	amino acid
L2I54_02430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L2I54_02460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_02460	COG1263	PTS System
L2I54_02465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2I54_02480	COG0463	Glycosyl transferase, family 2
L2I54_02490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L2I54_02490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2I54_02495	COG0463	Glycosyl transferase, family 2
L2I54_02510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L2I54_02530	COG1228	amidohydrolase
L2I54_02535	COG1090	epimerase
L2I54_02565	COG1988	membrane-bound metal-dependent
L2I54_02570	COG1194	a g-specific adenine glycosylase
L2I54_02595	COG1132	(ABC) transporter
L2I54_02600	COG4129	membrane
L2I54_02605	COG0070	glutamate synthase
L2I54_02605	COG0069	glutamate synthase activity
L2I54_02605	COG0067	glutamate synthase
L2I54_02615	COG4555	ABC transporter
L2I54_02635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2I54_02640	COG0735	belongs to the Fur family
L2I54_02760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L2I54_02785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2I54_02795	COG2766	serine protein kinase
L2I54_02815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2I54_02825	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2I54_02830	COG2268	Band 7 protein
L2I54_02840	COG3290	protein histidine kinase activity
L2I54_02845	COG4565	transcriptional regulatory protein
L2I54_02850	COG2851	Citrate transporter
L2I54_02875	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L2I54_02880	COG3842	ATPase activity
L2I54_02885	COG1175	transmembrane transport
L2I54_02890	COG0395	ABC-type sugar transport system, permease component
L2I54_02900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2I54_02905	COG0745	RESPONSE REGULATOR receiver
L2I54_02910	COG5002	protein histidine kinase activity
L2I54_02920	COG4990	cell redox homeostasis
L2I54_02930	COG3290	protein histidine kinase activity
L2I54_02935	COG4565	transcriptional regulatory protein
L2I54_02940	COG3493	citrate carrier protein
L2I54_02945	COG0281	malic enzyme
L2I54_02955	COG0697	spore germination
L2I54_02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_02970	COG5002	protein histidine kinase activity
L2I54_02985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2I54_02990	COG3383	formate dehydrogenase (NAD+) activity
L2I54_02995	COG2427	Protein of unknown function (DUF1641)
L2I54_03010	COG0531	amino acid
L2I54_03020	COG0640	Transcriptional regulator
L2I54_03025	COG2217	Heavy metal translocating P-type atpase
L2I54_03035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L2I54_03050	COG3227	Zinc metalloprotease (Elastase)
L2I54_03070	COG2720	vancomycin resistance protein
L2I54_03075	COG1316	TRANSCRIPTIONal
L2I54_03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_03085	COG0346	lactoylglutathione lyase activity
L2I54_03090	COG1253	flavin adenine dinucleotide binding
L2I54_03095	COG1027	Aspartate ammonia-lyase
L2I54_03100	COG1620	l-lactate permease
L2I54_03115	COG3104	oligopeptide transport
L2I54_03120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_03150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2I54_03160	COG4548	von Willebrand factor, type A
L2I54_03165	COG0714	Associated with various cellular activities
L2I54_03185	COG0531	amino acid
L2I54_03190	COG2188	Transcriptional regulator
L2I54_03195	COG1263	PTS System
L2I54_03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_03200	COG0366	Alpha amylase catalytic
L2I54_03215	COG0697	spore germination
L2I54_03225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2I54_03230	COG1115	amino acid carrier protein
L2I54_03235	COG1126	abc transporter atp-binding protein
L2I54_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2I54_03245	COG0765	amino acid transport
L2I54_03250	COG0765	amino acid transport
L2I54_03255	COG0833	amino acid
L2I54_03280	COG2378	regulation of single-species biofilm formation
L2I54_03285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2I54_03290	COG5002	protein histidine kinase activity
L2I54_03305	COG0659	secondary active sulfate transmembrane transporter activity
L2I54_03320	COG2271	Major facilitator Superfamily
L2I54_03325	COG1846	Transcriptional regulator
L2I54_03330	COG0477	Major facilitator Superfamily
L2I54_03335	COG1609	Transcriptional regulator
L2I54_03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2I54_03355	COG1172	Belongs to the binding-protein-dependent transport system permease family
L2I54_03360	COG1879	ABC-type sugar transport system periplasmic component
L2I54_03385	COG1063	alcohol dehydrogenase
L2I54_03435	COG0840	transmembrane signaling receptor activity
L2I54_03440	COG1388	LysM domain
L2I54_03440	COG3584	3D domain protein
L2I54_03445	COG1476	TRANSCRIPTIONal
L2I54_03465	COG3104	oligopeptide transport
L2I54_03470	COG1114	Component of the transport system for branched-chain amino acids
L2I54_03485	COG1113	amino acid transport
L2I54_03490	COG2252	PERMEase
L2I54_03515	COG2153	protein acetylation
L2I54_03525	COG0475	glutathione-regulated potassium exporter activity
L2I54_03525	COG0569	domain protein
L2I54_03540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2I54_03550	COG0833	amino acid
L2I54_03555	COG4990	cell redox homeostasis
L2I54_03570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2I54_03575	COG0697	spore germination
L2I54_03580	COG0531	amino acid
L2I54_03590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L2I54_03595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L2I54_03600	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L2I54_03600	COG1918	ferrous iron import across plasma membrane
L2I54_03605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2I54_03610	COG0573	inorganic phosphate transmembrane transporter activity
L2I54_03615	COG0581	inorganic phosphate transmembrane transporter activity
L2I54_03620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2I54_03740	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L2I54_03760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2I54_03765	COG1116	anion transmembrane transporter activity
L2I54_03770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2I54_03775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2I54_03780	COG0352	thiamine-phosphate diphosphorylase activity
L2I54_03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2I54_03790	COG2104	thiamine diphosphate biosynthetic process
L2I54_03800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L2I54_03805	COG0351	phosphomethylpyrimidine kinase
L2I54_03845	COG2205	protein histidine kinase activity
L2I54_03850	COG2814	Major facilitator Superfamily
L2I54_03855	COG1846	Transcriptional regulator
L2I54_03865	COG2252	PERMEase
L2I54_03870	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_03885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2I54_03890	COG1621	beta-fructofuranosidase activity
L2I54_03895	COG1263	PTS System
L2I54_03895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_03900	COG1609	Transcriptional regulator
L2I54_03950	COG0778	Nitroreductase
L2I54_03955	COG2719	SpoVR family
L2I54_03975	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2I54_03980	COG1937	Protein conserved in bacteria
L2I54_03985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_03985	COG0425	Belongs to the sulfur carrier protein TusA family
L2I54_03990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_03990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_03995	COG0425	Belongs to the sulfur carrier protein TusA family
L2I54_04000	COG0425	Belongs to the sulfur carrier protein TusA family
L2I54_04000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_04005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_04010	COG2210	Belongs to the sulfur carrier protein TusA family
L2I54_04015	COG0730	response to heat
L2I54_04025	COG1316	TRANSCRIPTIONal
L2I54_04030	COG0604	alcohol dehydrogenase
L2I54_04035	COG1283	sodium-dependent phosphate transmembrane transporter activity
L2I54_04050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2I54_04050	COG3711	transcriptional antiterminator
L2I54_04055	COG1447	Phosphotransferase system cellobiose-specific component IIA
L2I54_04060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L2I54_04080	COG3584	3D domain protein
L2I54_04080	COG1388	LysM domain
L2I54_04085	COG0577	efflux transmembrane transporter activity
L2I54_04090	COG1136	(ABC) transporter
L2I54_04100	COG5522	Integral membrane protein (intg_mem_TP0381)
L2I54_04115	COG1114	Component of the transport system for branched-chain amino acids
L2I54_04120	COG3546	catalase activity
L2I54_04155	COG0586	Pfam SNARE associated Golgi protein
L2I54_04190	COG0531	amino acid
L2I54_04195	COG0475	glutathione-regulated potassium exporter activity
L2I54_04205	COG1737	Transcriptional regulator
L2I54_04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_04215	COG1263	PTS System
L2I54_04225	COG2259	Doxx family
L2I54_04245	COG1522	sequence-specific DNA binding
L2I54_04250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
L2I54_04250	COG0165	Argininosuccinate lyase
L2I54_04255	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_04275	COG1309	transcriptional regulator
L2I54_04280	COG2814	Major facilitator Superfamily
L2I54_04285	COG1733	regulation of RNA biosynthetic process
L2I54_04295	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2I54_04300	COG0747	negative chemotaxis
L2I54_04305	COG2211	Major facilitator Superfamily
L2I54_04320	COG0693	protein deglycase activity
L2I54_04325	COG0693	protein deglycase activity
L2I54_04325	COG0753	catalase activity
L2I54_04335	COG0531	amino acid
L2I54_04350	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_04355	COG1132	(ABC) transporter
L2I54_04360	COG1132	(ABC) transporter
L2I54_04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2I54_04370	COG0765	amino acid transport
L2I54_04375	COG1126	abc transporter atp-binding protein
L2I54_04390	COG0189	ligase activity
L2I54_04410	COG4585	Histidine kinase
L2I54_04415	COG2197	response regulator
L2I54_04420	COG0028	Belongs to the TPP enzyme family
L2I54_04425	COG3527	Alpha-acetolactate decarboxylase
L2I54_04435	COG0561	phosphatase activity
L2I54_04445	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_04445	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_04450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2I54_04470	COG0659	secondary active sulfate transmembrane transporter activity
L2I54_04475	COG2244	polysaccharide biosynthetic process
L2I54_04495	COG1024	Enoyl-CoA hydratase
L2I54_04515	COG1363	Peptidase, m42
L2I54_04550	COG0601	transmembrane transport
L2I54_04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2I54_04560	COG0444	Belongs to the ABC transporter superfamily
L2I54_04565	COG4608	Belongs to the ABC transporter superfamily
L2I54_04575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_04645	COG0477	Major facilitator Superfamily
L2I54_04650	COG3290	protein histidine kinase activity
L2I54_04655	COG4565	transcriptional regulatory protein
L2I54_04660	COG3181	Tripartite tricarboxylate transporter family receptor
L2I54_04760	COG0305	Participates in initiation and elongation during chromosome replication
L2I54_04790	COG0477	Major facilitator Superfamily
L2I54_04820	COG5504	Zn-dependent protease
L2I54_04825	COG0789	Transcriptional regulator
L2I54_04860	COG1329	Transcriptional regulator
L2I54_04880	COG1278	Cold shock
L2I54_04890	COG4932	domain protein
L2I54_04890	COG3266	domain, Protein
L2I54_04890	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
L2I54_04980	COG1183	phosphatidylcholine synthase activity
L2I54_04995	COG2376	Dihydroxyacetone kinase
L2I54_05005	COG2376	Dihydroxyacetone kinase
L2I54_05035	COG0457	Tetratricopeptide repeat
L2I54_05060	COG3584	3D domain protein
L2I54_05060	COG1388	LysM domain
L2I54_05065	COG0791	NLP P60 protein
L2I54_05065	COG1388	LysM domain
L2I54_05075	COG2373	Large extracellular alpha-helical protein
L2I54_05120	COG3237	CsbD-like
L2I54_05145	COG1191	sigma factor activity
L2I54_05155	COG2208	phosphoserine phosphatase activity
L2I54_05160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L2I54_05165	COG2205	protein histidine kinase activity
L2I54_05165	COG5002	protein histidine kinase activity
L2I54_05165	COG0784	Response regulator, receiver
L2I54_05210	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
L2I54_05230	COG0420	3'-5' exonuclease activity
L2I54_05235	COG4717	serine-type aminopeptidase activity
L2I54_05250	COG1280	lysine exporter protein (LysE YggA)
L2I54_05255	COG0346	lactoylglutathione lyase activity
L2I54_05260	COG0346	lactoylglutathione lyase activity
L2I54_05265	COG0457	Tetratricopeptide repeat
L2I54_05275	COG2267	carboxylic ester hydrolase activity
L2I54_05300	COG2140	Oxalate decarboxylase
L2I54_05305	COG3620	sequence-specific DNA binding
L2I54_05310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L2I54_05315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L2I54_05325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L2I54_05350	COG0772	Belongs to the SEDS family
L2I54_05355	COG3973	AAA domain
L2I54_05365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2I54_05385	COG4980	gas vesicle protein
L2I54_05390	COG0537	adenosine 5'-monophosphoramidase activity
L2I54_05395	COG1131	(ABC) transporter
L2I54_05400	COG4473	ABC transporter
L2I54_05425	COG3402	PFAM membrane-flanked domain
L2I54_05430	COG3428	Bacterial PH domain
L2I54_05460	COG0697	spore germination
L2I54_05465	COG3402	PFAM membrane-flanked domain
L2I54_05470	COG3428	Bacterial PH domain
L2I54_05475	COG2329	Antibiotic biosynthesis monooxygenase
L2I54_05480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2I54_05495	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L2I54_05530	COG1309	transcriptional regulator
L2I54_05535	COG1511	domain protein
L2I54_05555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_05565	COG2378	regulation of single-species biofilm formation
L2I54_05570	COG1609	Transcriptional regulator
L2I54_05580	COG1234	tRNA 3'-trailer cleavage
L2I54_05585	COG0095	Lipoate-protein ligase
L2I54_05595	COG0318	PFAM AMP-dependent synthetase and ligase
L2I54_05715	COG1408	metallophosphoesterase
L2I54_05720	COG1078	dGTPase activity
L2I54_05735	COG2207	Transcriptional regulator
L2I54_05735	COG3708	Transcriptional regulator
L2I54_05745	COG2205	protein histidine kinase activity
L2I54_05750	COG0745	RESPONSE REGULATOR receiver
L2I54_05770	COG0501	Belongs to the peptidase M48B family
L2I54_05775	COG0840	transmembrane signaling receptor activity
L2I54_05780	COG3693	PFAM glycoside hydrolase, family 10
L2I54_05790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2I54_05795	COG2224	Isocitrate lyase
L2I54_05835	COG0398	Pfam SNARE associated Golgi protein
L2I54_05895	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2I54_05920	COG0367	asparagine synthase
L2I54_05930	COG0753	catalase activity
L2I54_05935	COG0004	ammonium transporteR
L2I54_05955	COG2996	Protein conserved in bacteria
L2I54_05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_05985	COG0561	phosphatase activity
L2I54_06005	COG2267	carboxylic ester hydrolase activity
L2I54_06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2I54_06030	COG5504	Zn-dependent protease
L2I54_06040	COG0180	Tryptophanyl-tRNA synthetase
L2I54_06050	COG4166	transmembrane transport
L2I54_06055	COG0601	transmembrane transport
L2I54_06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2I54_06065	COG0444	Belongs to the ABC transporter superfamily
L2I54_06070	COG4608	Belongs to the ABC transporter superfamily
L2I54_06075	COG0534	Mate efflux family protein
L2I54_06080	COG4166	transmembrane transport
L2I54_06095	COG0861	Integral membrane protein TerC family
L2I54_06115	COG1164	Oligoendopeptidase f
L2I54_06130	COG2346	COG2346, Truncated hemoglobins
L2I54_06135	COG3956	TIGRFAM MazG family protein
L2I54_06150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2I54_06180	COG0251	oxidation-reduction process
L2I54_06190	COG0457	Tetratricopeptide repeat
L2I54_06190	COG0463	Glycosyl transferase, family 2
L2I54_06210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L2I54_06225	COG1091	dTDP-4-dehydrorhamnose reductase activity
L2I54_06270	COG2153	protein acetylation
L2I54_06280	COG2382	esterase
L2I54_06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2I54_06310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2I54_06310	COG0512	Glutamine amidotransferase of anthranilate synthase
L2I54_06345	COG1620	l-lactate permease
L2I54_06350	COG5634	Uncharacterized conserved protein (DUF2278)
L2I54_06400	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2I54_06410	COG1476	TRANSCRIPTIONal
L2I54_06500	COG1686	Belongs to the peptidase S11 family
L2I54_06505	COG0681	Belongs to the peptidase S26 family
L2I54_06540	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
L2I54_06555	COG1177	transmembrane transport
L2I54_06570	COG2409	Drug exporters of the RND superfamily
L2I54_06580	COG0564	pseudouridine synthase activity
L2I54_06590	COG2340	Cysteine-rich secretory protein family
L2I54_06595	COG0247	lactate metabolic process
L2I54_06600	COG0277	FAD linked oxidase domain protein
L2I54_06605	COG3835	regulator
L2I54_06615	COG0745	RESPONSE REGULATOR receiver
L2I54_06620	COG5002	protein histidine kinase activity
L2I54_06625	COG2186	Transcriptional regulator
L2I54_06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2I54_06655	COG2116	formate transmembrane transporter activity
L2I54_06660	COG0861	Integral membrane protein TerC family
L2I54_06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2I54_06675	COG2030	dehydratase
L2I54_06695	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_06700	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2I54_06710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2I54_06725	COG1840	ABC-type Fe3 transport system, periplasmic component
L2I54_06730	COG3842	ATPase activity
L2I54_06755	COG1349	DNA-binding transcription factor activity
L2I54_06765	COG0235	Class ii aldolase
L2I54_06775	COG2861	carbohydrate metabolic process
L2I54_06785	COG3852	Histidine kinase
L2I54_06790	COG1846	Transcriptional regulator
L2I54_06800	COG2318	DinB family
L2I54_06810	COG5002	protein histidine kinase activity
L2I54_06820	COG0720	synthase
L2I54_06835	COG4873	Protein conserved in bacteria
L2I54_06865	COG1780	Probably involved in ribonucleotide reductase function
L2I54_06900	COG1725	Transcriptional regulator
L2I54_06905	COG1131	(ABC) transporter
L2I54_06915	COG1131	(ABC) transporter
L2I54_06935	COG1522	sequence-specific DNA binding
L2I54_06945	COG1335	isochorismatase
L2I54_06955	COG1619	proteins homologs of microcin C7 resistance protein MccF
L2I54_06960	COG2070	2-Nitropropane dioxygenase
L2I54_06965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L2I54_06975	COG1696	Membrane protein involved in D-alanine export
L2I54_07000	COG0716	FMN binding
L2I54_07015	COG3173	Aminoglycoside phosphotransferase
L2I54_07055	COG1846	Transcriptional regulator
L2I54_07065	COG1301	dicarboxylic acid transport
L2I54_07070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2I54_07075	COG4709	membrane
L2I54_07080	COG3874	Sporulation protein YtfJ
L2I54_07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2I54_07105	COG0028	Belongs to the TPP enzyme family
L2I54_07110	COG0440	acetolactate synthase activity
L2I54_07185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L2I54_07200	COG1183	phosphatidylcholine synthase activity
L2I54_07205	COG1368	sulfuric ester hydrolase activity
L2I54_07215	COG0019	diaminopimelate decarboxylase activity
L2I54_07235	COG0529	Catalyzes the synthesis of activated sulfate
L2I54_07240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2I54_07260	COG1648	precorrin-2 dehydrogenase activity
L2I54_07265	COG0733	neurotransmitter:sodium symporter activity
L2I54_07285	COG1757	Na H antiporter
L2I54_07300	COG4758	membrane
L2I54_07305	COG4585	Histidine kinase
L2I54_07310	COG2197	response regulator
L2I54_07320	COG1114	Component of the transport system for branched-chain amino acids
L2I54_07330	COG2226	methyltransferase
L2I54_07370	COG0730	response to heat
L2I54_07375	COG0306	phosphate transporter
L2I54_07380	COG1392	Phosphate transport regulator
L2I54_07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2I54_07400	COG3852	Histidine kinase
L2I54_07405	COG1801	Protein of unknown function DUF72
L2I54_07415	COG0582	viral genome integration into host DNA
L2I54_07420	COG5002	protein histidine kinase activity
L2I54_07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L2I54_07435	COG0392	lysyltransferase activity
L2I54_07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2I54_07455	COG1686	Belongs to the peptidase S11 family
L2I54_07460	COG2715	membrane protein required for spore maturation
L2I54_07465	COG0700	Nucleoside recognition
L2I54_07470	COG1187	pseudouridine synthase activity
L2I54_07480	COG1333	cytochrome c biogenesis protein
L2I54_07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L2I54_07490	COG0745	RESPONSE REGULATOR receiver
L2I54_07495	COG5002	protein histidine kinase activity
L2I54_07500	COG2096	Adenosyltransferase
L2I54_07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L2I54_07520	COG1141	Ferredoxin
L2I54_07530	COG0514	ATP-dependent DNA helicase (RecQ)
L2I54_07535	COG1266	CAAX protease self-immunity
L2I54_07545	COG1408	metallophosphoesterase
L2I54_07550	COG0789	Transcriptional regulator
L2I54_07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2I54_07580	COG0492	ferredoxin-NADP+ reductase activity
L2I54_07585	COG0252	asparaginase activity
L2I54_07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L2I54_07670	COG0142	geranyltranstransferase activity
L2I54_07680	COG0142	geranyltranstransferase activity
L2I54_07705	COG0457	Tetratricopeptide repeat
L2I54_07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L2I54_07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L2I54_07730	COG2010	Cytochrome c
L2I54_07735	COG4347	Protein of unknown function (DUF1405)
L2I54_07750	COG2738	Putative neutral zinc metallopeptidase
L2I54_07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_07765	COG1694	Mazg nucleotide pyrophosphohydrolase
L2I54_07785	COG0438	transferase activity, transferring glycosyl groups
L2I54_07820	COG1199	ATP-dependent helicase activity
L2I54_07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2I54_07840	COG3935	DnaD domain protein
L2I54_07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2I54_07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2I54_07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
L2I54_07910	COG0116	Belongs to the methyltransferase superfamily
L2I54_07920	COG1199	ATP-dependent helicase activity
L2I54_07925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L2I54_07935	COG0024	Methionine aminopeptidase
L2I54_07945	COG2233	PERMEase
L2I54_07955	COG2311	Membrane
L2I54_07960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L2I54_07970	COG0456	acetyltransferase
L2I54_08020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2I54_08035	COG3944	biosynthesis protein
L2I54_08045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2I54_08060	COG1215	transferase activity, transferring glycosyl groups
L2I54_08065	COG0438	transferase activity, transferring glycosyl groups
L2I54_08080	COG0454	-acetyltransferase
L2I54_08100	COG0328	RNA-DNA hybrid ribonuclease activity
L2I54_08135	COG3403	YqcI/YcgG family
L2I54_08140	COG1280	lysine exporter protein (LysE YggA)
L2I54_08160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2I54_08165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L2I54_08175	COG0475	glutathione-regulated potassium exporter activity
L2I54_08180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L2I54_08185	COG4978	Transcriptional regulator
L2I54_08185	COG0789	Transcriptional regulator
L2I54_08195	COG2323	membrane
L2I54_08200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L2I54_08250	COG1923	regulation of RNA biosynthetic process
L2I54_08260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L2I54_08265	COG1360	Flagellar Motor Protein
L2I54_08270	COG2201	protein-glutamate methylesterase activity
L2I54_08275	COG2198	Histidine kinase
L2I54_08275	COG0643	Histidine kinase
L2I54_08280	COG1776	CheC inhibitor of MCP methylation
L2I54_08280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L2I54_08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L2I54_08315	COG1256	bacterial-type flagellum assembly
L2I54_08320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L2I54_08340	COG1815	bacterial-type flagellum-dependent cell motility
L2I54_08345	COG1558	bacterial-type flagellum-dependent cell motility
L2I54_08355	COG1766	The M ring may be actively involved in energy transduction
L2I54_08360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L2I54_08370	COG1157	protein secretion by the type III secretion system
L2I54_08390	COG1749	Flagellar hook protein flgE
L2I54_08405	COG0784	Response regulator, receiver
L2I54_08405	COG0835	chemotaxis
L2I54_08415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L2I54_08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L2I54_08425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L2I54_08430	COG0741	lytic transglycosylase activity
L2I54_08440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L2I54_08445	COG1776	CheC inhibitor of MCP methylation
L2I54_08445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L2I54_08455	COG1338	Plays a role in the flagellum-specific transport system
L2I54_08460	COG1987	bacterial-type flagellum assembly
L2I54_08470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L2I54_08475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L2I54_08480	COG1419	protein localization to endoplasmic reticulum
L2I54_08485	COG4786	Flagellar basal body rod
L2I54_08490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L2I54_08525	COG2329	Antibiotic biosynthesis monooxygenase
L2I54_08550	COG0583	DNA-binding transcription factor activity
L2I54_08600	COG0406	alpha-ribazole phosphatase activity
L2I54_08630	COG0367	asparagine synthase
L2I54_08665	COG1802	Transcriptional regulator
L2I54_08670	COG0697	spore germination
L2I54_08680	COG0523	cobalamin synthesis protein
L2I54_08685	COG0701	Predicted permease
L2I54_08700	COG1757	Na H antiporter
L2I54_08705	COG0789	Transcriptional regulator
L2I54_08730	COG0534	Mate efflux family protein
L2I54_08735	COG3340	Belongs to the peptidase S51 family
L2I54_08755	COG0785	Cytochrome C biogenesis protein
L2I54_08775	COG0457	Tetratricopeptide repeat
L2I54_08795	COG2733	membrane
L2I54_08830	COG1131	(ABC) transporter
L2I54_08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2I54_08850	COG0528	UMP kinase activity
L2I54_08865	COG1027	Aspartate ammonia-lyase
L2I54_08870	COG0281	malic enzyme
L2I54_08875	COG4191	Histidine kinase
L2I54_08880	COG0784	Response regulator, receiver
L2I54_08885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L2I54_08930	COG2814	Major facilitator Superfamily
L2I54_08945	COG1695	Transcriptional regulator
L2I54_08955	COG0477	Major facilitator Superfamily
L2I54_08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2I54_08970	COG2223	nitrite transmembrane transporter activity
L2I54_08975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2I54_08995	COG0733	neurotransmitter:sodium symporter activity
L2I54_09005	COG5566	PFAM Mor transcription activator
L2I54_09010	COG2323	membrane
L2I54_09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L2I54_09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2I54_09045	COG0028	Belongs to the TPP enzyme family
L2I54_09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2I54_09090	COG2814	Major facilitator Superfamily
L2I54_09095	COG3384	dioxygenase
L2I54_09105	COG3279	Response regulator of the LytR AlgR family
L2I54_09110	COG0427	acetyl-CoA hydrolase
L2I54_09130	COG4166	transmembrane transport
L2I54_09150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_09170	COG1914	H( )-stimulated, divalent metal cation uptake system
L2I54_09185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L2I54_09190	COG0531	amino acid
L2I54_09220	COG2309	aminopeptidase activity
L2I54_09235	COG0456	acetyltransferase
L2I54_09250	COG1309	transcriptional regulator
L2I54_09255	COG2390	Transcriptional regulator
L2I54_09265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_09270	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L2I54_09280	COG4846	Membrane protein involved in cytochrome C biogenesis
L2I54_09290	COG0006	proline dipeptidase activity
L2I54_09300	COG2132	Multicopper oxidase
L2I54_09310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L2I54_09330	COG1114	Component of the transport system for branched-chain amino acids
L2I54_09340	COG1910	domain protein
L2I54_09360	COG2318	DinB family
L2I54_09365	COG4122	O-methyltransferase activity
L2I54_09370	COG1280	lysine exporter protein (LysE YggA)
L2I54_09375	COG3403	YqcI/YcgG family
L2I54_09390	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2I54_09395	COG0561	phosphatase activity
L2I54_09400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
L2I54_09410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2I54_09415	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_09455	COG2372	response to copper ion
L2I54_09455	COG1276	copper resistance
L2I54_09460	COG4549	nuclear export factor GLE1
L2I54_09465	COG0697	spore germination
L2I54_09470	COG0583	DNA-binding transcription factor activity
L2I54_09475	COG1959	2 iron, 2 sulfur cluster binding
L2I54_09480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2I54_09485	COG0778	Nitroreductase
L2I54_09495	COG0628	permease
L2I54_09505	COG1231	oxidoreductase activity
L2I54_09510	COG0523	cobalamin synthesis protein
L2I54_09520	COG0411	ABC transporter
L2I54_09540	COG0583	DNA-binding transcription factor activity
L2I54_09570	COG1271	oxidase subunit
L2I54_09575	COG1294	oxidase, subunit
L2I54_09580	COG4988	ABC transporter
L2I54_09585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L2I54_09595	COG1216	Glycosyl transferase, family 2
L2I54_09635	COG1686	Belongs to the peptidase S11 family
L2I54_09650	COG1388	LysM domain
L2I54_09650	COG0791	NLP P60 protein
L2I54_09660	COG1132	(ABC) transporter
L2I54_09665	COG0745	RESPONSE REGULATOR receiver
L2I54_09670	COG5002	protein histidine kinase activity
L2I54_09680	COG0300	oxidoreductase activity
L2I54_09710	COG0460	homoserine dehydrogenase
L2I54_09735	COG1316	TRANSCRIPTIONal
L2I54_09745	COG0745	RESPONSE REGULATOR receiver
L2I54_09750	COG5002	protein histidine kinase activity
L2I54_09765	COG1285	pathogenesis
L2I54_09795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2I54_09805	COG1082	Xylose isomerase domain protein TIM barrel
L2I54_09815	COG2814	Major facilitator Superfamily
L2I54_09820	COG1279	arginine transmembrane transporter activity
L2I54_09825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_09835	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2I54_09870	COG0577	efflux transmembrane transporter activity
L2I54_09875	COG2002	toxin-antitoxin pair type II binding
L2I54_09880	COG1404	Belongs to the peptidase S8 family
L2I54_09885	COG0640	Transcriptional regulator
L2I54_09890	COG0667	Aldo Keto reductase
L2I54_09895	COG2814	Major facilitator Superfamily
L2I54_09900	COG3152	Membrane
L2I54_09925	COG0840	transmembrane signaling receptor activity
L2I54_09940	COG3949	Membrane
L2I54_09945	COG0783	Belongs to the Dps family
L2I54_09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2I54_09970	COG1231	oxidoreductase activity
L2I54_09975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_09980	COG4989	oxidoreductase activity
L2I54_09985	COG0523	cobalamin synthesis protein
L2I54_09990	COG0456	acetyltransferase
L2I54_09995	COG0803	Belongs to the bacterial solute-binding protein 9 family
L2I54_10005	COG0702	epimerase
L2I54_10015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2I54_10025	COG4166	transmembrane transport
L2I54_10050	COG5337	Spore coat protein CotH
L2I54_10055	COG1051	belongs to the nudix hydrolase family
L2I54_10060	COG0586	Pfam SNARE associated Golgi protein
L2I54_10065	COG2244	polysaccharide biosynthetic process
L2I54_10075	COG0701	Predicted permease
L2I54_10080	COG3689	TIGRFAM TIGR03943 family protein
L2I54_10085	COG1607	acyl-coa hydrolase
L2I54_10095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2I54_10110	COG0702	epimerase
L2I54_10115	COG2839	Protein conserved in bacteria
L2I54_10120	COG1253	flavin adenine dinucleotide binding
L2I54_10135	COG1114	Component of the transport system for branched-chain amino acids
L2I54_10140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2I54_10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
L2I54_10170	COG1876	peptidase activity
L2I54_10180	COG0154	amidase activity
L2I54_10185	COG2211	Major facilitator Superfamily
L2I54_10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
L2I54_10210	COG0561	phosphatase activity
L2I54_10225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2I54_10245	COG1819	glycosyl
L2I54_10250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_10285	COG0456	acetyltransferase
L2I54_10320	COG4499	WXG100 protein secretion system (Wss), protein YukC
L2I54_10375	COG3874	Sporulation protein YtfJ
L2I54_10400	COG2226	methyltransferase
L2I54_10420	COG1082	Xylose isomerase domain protein TIM barrel
L2I54_10425	COG0346	lactoylglutathione lyase activity
L2I54_10435	COG0604	alcohol dehydrogenase
L2I54_10440	COG1595	DNA-templated transcription, initiation
L2I54_10455	COG0426	domain, Protein
L2I54_10455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2I54_10465	COG0386	Belongs to the glutathione peroxidase family
L2I54_10470	COG1305	Transglutaminase-like
L2I54_10475	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L2I54_10480	COG0714	Associated with various cellular activities
L2I54_10485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L2I54_10490	COG1140	nitrate reductase beta subunit
L2I54_10495	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L2I54_10500	COG2181	nitrate reductase activity
L2I54_10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2I54_10510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2I54_10515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L2I54_10520	COG0303	'Molybdopterin
L2I54_10525	COG0314	molybdopterin synthase activity
L2I54_10535	COG2223	nitrite transmembrane transporter activity
L2I54_10555	COG1648	precorrin-2 dehydrogenase activity
L2I54_10565	COG1587	Uroporphyrinogen-III synthase
L2I54_10565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2I54_10570	COG2146	nitrite reductase [NAD(P)H] activity
L2I54_10575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2I54_10580	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L2I54_10615	COG2359	stage V sporulation protein S
L2I54_10640	COG0457	Tetratricopeptide repeat
L2I54_10655	COG2856	Zn peptidase
L2I54_10660	COG1396	sequence-specific DNA binding
L2I54_10710	COG0662	Cupin 2, conserved barrel domain protein
L2I54_10730	COG0582	viral genome integration into host DNA
L2I54_10750	COG0582	viral genome integration into host DNA
L2I54_10765	COG5484	DNA packaging
L2I54_10770	COG1783	phage Terminase large subunit
L2I54_10785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
L2I54_10915	COG0457	Tetratricopeptide repeat
L2I54_10950	COG1418	mRNA catabolic process
L2I54_10955	COG0488	(ABC) transporter
L2I54_10970	COG0629	single-stranded DNA binding
L2I54_10975	COG1413	lyase activity
L2I54_10990	COG2136	Putative SAM-dependent methyltransferase
L2I54_10990	COG2521	methyltransferase
L2I54_10995	COG0018	arginyl-trna synthetase
L2I54_11035	COG0017	Asparaginyl-tRNA synthetase
L2I54_11040	COG1929	Belongs to the glycerate kinase type-1 family
L2I54_11050	COG0745	RESPONSE REGULATOR receiver
L2I54_11055	COG5002	protein histidine kinase activity
L2I54_11055	COG3850	Histidine kinase
L2I54_11070	COG0733	neurotransmitter:sodium symporter activity
L2I54_11095	COG2610	gluconate transmembrane transporter activity
L2I54_11105	COG1794	racemase activity, acting on amino acids and derivatives
L2I54_11115	COG0456	acetyltransferase
L2I54_11125	COG3655	Transcriptional regulator
L2I54_11130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L2I54_11140	COG1131	(ABC) transporter
L2I54_11145	COG4473	ABC transporter
L2I54_11175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2I54_11190	COG0768	penicillin binding
L2I54_11200	COG0204	Acyl-transferase
L2I54_11205	COG1272	protein, Hemolysin III
L2I54_11215	COG0805	protein transport
L2I54_11225	COG1307	EDD domain protein, DegV family
L2I54_11235	COG1999	signal sequence binding
L2I54_11240	COG0071	Belongs to the small heat shock protein (HSP20) family
L2I54_11245	COG0367	asparagine synthase
L2I54_11260	COG0860	N-Acetylmuramoyl-L-alanine amidase
L2I54_11265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_11270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2I54_11285	COG1335	isochorismatase
L2I54_11300	COG0668	transmembrane transport
L2I54_11305	COG2203	Gaf domain
L2I54_11305	COG4585	Histidine kinase
L2I54_11310	COG2197	response regulator
L2I54_11315	COG1737	Transcriptional regulator
L2I54_11325	COG1064	alcohol dehydrogenase
L2I54_11350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L2I54_11385	COG0517	IMP dehydrogenase activity
L2I54_11385	COG1125	glycine betaine transport
L2I54_11390	COG1174	glycine betaine transport
L2I54_11425	COG1253	flavin adenine dinucleotide binding
L2I54_11430	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_11435	COG5506	Protein of unknown function (DUF1694)
L2I54_11450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L2I54_11455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2I54_11460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2I54_11465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L2I54_11470	COG0456	acetyltransferase
L2I54_11475	COG3829	transcription factor binding
L2I54_11480	COG1509	lysine 2,3-aminomutase activity
L2I54_11515	COG0515	serine threonine protein kinase
L2I54_11515	COG4991	sh3 domain protein
L2I54_11515	COG3064	Membrane
L2I54_11525	COG0671	phosphoesterase, PA-phosphatase related
L2I54_11530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L2I54_11535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L2I54_11630	COG0300	oxidoreductase activity
L2I54_11650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2I54_11650	COG4499	WXG100 protein secretion system (Wss), protein YukC
L2I54_11660	COG2814	Major facilitator Superfamily
L2I54_11665	COG4841	protein insertion into membrane
L2I54_11670	COG0372	Belongs to the citrate synthase family
L2I54_11675	COG2079	MmgE PrpD family protein
L2I54_11680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L2I54_11685	COG1960	acyl-CoA dehydrogenase activity
L2I54_11690	COG2084	Dehydrogenase
L2I54_11700	COG1280	lysine exporter protein (LysE YggA)
L2I54_11705	COG1024	Enoyl-CoA hydratase
L2I54_11720	COG0420	3'-5' exonuclease activity
L2I54_11725	COG0419	ATPase involved in DNA repair
L2I54_11750	COG2223	nitrite transmembrane transporter activity
L2I54_11755	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_11760	COG1169	isochorismate synthase
L2I54_11765	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2I54_11770	COG1535	isochorismatase
L2I54_11770	COG3433	isochorismatase activity
L2I54_11775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2I54_11780	COG3251	PFAM MbtH domain protein
L2I54_11785	COG2814	Major facilitator Superfamily
L2I54_11800	COG0776	regulation of translation
L2I54_11810	COG2318	DinB family
L2I54_11820	COG1115	amino acid carrier protein
L2I54_11835	COG2329	Antibiotic biosynthesis monooxygenase
L2I54_11840	COG1187	pseudouridine synthase activity
L2I54_11845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L2I54_11850	COG1136	(ABC) transporter
L2I54_11895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2I54_11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_11955	COG1247	-acetyltransferase
L2I54_11980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L2I54_11990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_12020	COG0583	DNA-binding transcription factor activity
L2I54_12025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L2I54_12040	COG0583	DNA-binding transcription factor activity
L2I54_12045	COG2258	MOSC domain
L2I54_12060	COG1132	(ABC) transporter
L2I54_12065	COG1132	(ABC) transporter
L2I54_12170	COG1396	sequence-specific DNA binding
L2I54_12200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2I54_12205	COG1595	DNA-templated transcription, initiation
L2I54_12235	COG1649	PFAM Uncharacterised BCR, COG1649
L2I54_12260	COG2971	BadF BadG BcrA BcrD
L2I54_12270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2I54_12280	COG1846	Transcriptional regulator
L2I54_12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_12320	COG1309	transcriptional regulator
L2I54_12405	COG0500	methyltransferase
L2I54_12405	COG3615	Tellurite resistance protein tehB
L2I54_12415	COG2226	methyltransferase
L2I54_12425	COG1846	Transcriptional regulator
L2I54_12455	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2I54_12485	COG2002	toxin-antitoxin pair type II binding
L2I54_12495	COG0730	response to heat
L2I54_12500	COG0110	maltose O-acetyltransferase activity
L2I54_12505	COG1686	Belongs to the peptidase S11 family
L2I54_12520	COG2814	Major facilitator Superfamily
L2I54_12555	COG2312	Erythromycin esterase
L2I54_12565	COG0741	lytic transglycosylase activity
L2I54_12570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_12620	COG0277	FAD linked oxidase domain protein
L2I54_12625	COG0577	efflux transmembrane transporter activity
L2I54_12630	COG1136	(ABC) transporter
L2I54_12665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2I54_12670	COG0768	penicillin binding
L2I54_12675	COG1595	DNA-templated transcription, initiation
L2I54_12685	COG0768	penicillin binding
L2I54_12690	COG0768	penicillin binding
L2I54_12700	COG1408	metallophosphoesterase
L2I54_12710	COG1131	(ABC) transporter
L2I54_12720	COG1309	transcriptional regulator
L2I54_12735	COG1960	acyl-CoA dehydrogenase activity
L2I54_12740	COG0439	Biotin carboxylase
L2I54_12745	COG0511	ligase activity, forming carbon-carbon bonds
L2I54_12750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2I54_12755	COG1024	Enoyl-CoA hydratase
L2I54_12760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2I54_12765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2I54_12785	COG0572	uridine kinase
L2I54_12810	COG1686	Belongs to the peptidase S11 family
L2I54_12835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2I54_12850	COG3227	Zinc metalloprotease (Elastase)
L2I54_12855	COG2207	Transcriptional regulator
L2I54_12885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2I54_12895	COG2814	Major facilitator Superfamily
L2I54_12900	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_12905	COG1733	regulation of RNA biosynthetic process
L2I54_12950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_12975	COG1063	alcohol dehydrogenase
L2I54_12985	COG2323	membrane
L2I54_12990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2I54_13000	COG3386	PFAM SMP-30 Gluconolaconase
L2I54_13010	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L2I54_13015	COG3773	Cell wall hydrolase
L2I54_13025	COG0745	RESPONSE REGULATOR receiver
L2I54_13030	COG2205	protein histidine kinase activity
L2I54_13040	COG0488	(ABC) transporter
L2I54_13055	COG1136	(ABC) transporter
L2I54_13060	COG0577	efflux transmembrane transporter activity
L2I54_13080	COG0460	homoserine dehydrogenase
L2I54_13085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_13095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2I54_13125	COG0582	viral genome integration into host DNA
L2I54_13140	COG1396	sequence-specific DNA binding
L2I54_13165	COG2002	toxin-antitoxin pair type II binding
L2I54_13230	COG0582	viral genome integration into host DNA
L2I54_13360	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_13405	COG2124	cytochrome p450
L2I54_13450	COG0561	phosphatase activity
L2I54_13455	COG5002	protein histidine kinase activity
L2I54_13460	COG0768	penicillin binding
L2I54_13470	COG1819	glycosyl
L2I54_13475	COG1794	racemase activity, acting on amino acids and derivatives
L2I54_13500	COG2205	protein histidine kinase activity
L2I54_13560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2I54_13565	COG0604	alcohol dehydrogenase
L2I54_13570	COG0671	phosphoesterase, PA-phosphatase related
L2I54_13575	COG0768	penicillin binding
L2I54_13615	COG0693	protein deglycase activity
L2I54_13630	COG0584	glycerophosphoryl diester phosphodiesterase
L2I54_13650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_13655	COG0697	spore germination
L2I54_13690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2I54_13700	COG2223	nitrite transmembrane transporter activity
L2I54_13720	COG0592	DNA-directed DNA polymerase activity
L2I54_13750	COG3878	Protein conserved in bacteria
L2I54_13770	COG4667	esterase of the alpha-beta hydrolase superfamily
L2I54_13810	COG0322	excinuclease ABC activity
L2I54_13850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2I54_13885	COG1011	Hydrolase
L2I54_13900	COG1073	alpha beta
L2I54_13905	COG0657	acetylesterase activity
L2I54_13910	COG0076	glutamate decarboxylase activity
L2I54_13925	COG1523	belongs to the glycosyl hydrolase 13 family
L2I54_13930	COG3227	Zinc metalloprotease (Elastase)
L2I54_13935	COG0737	Belongs to the 5'-nucleotidase family
L2I54_13950	COG0201	protein transport
L2I54_13955	COG0697	spore germination
L2I54_13960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_13995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_14010	COG2959	enzyme of heme biosynthesis
L2I54_14050	COG1309	transcriptional regulator
L2I54_14070	COG3284	Transcriptional regulator
L2I54_14085	COG1349	DNA-binding transcription factor activity
L2I54_14100	COG1959	2 iron, 2 sulfur cluster binding
L2I54_14115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2I54_14120	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2I54_14125	COG0022	dehydrogenase e1 component
L2I54_14130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2I54_14145	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_14175	COG4176	ABC-type proline glycine betaine transport system permease component
L2I54_14180	COG4175	Glycine betaine
L2I54_14180	COG0517	IMP dehydrogenase activity
L2I54_14210	COG2153	protein acetylation
L2I54_14215	COG3397	chitin binding
L2I54_14220	COG1819	glycosyl
L2I54_14240	COG2205	protein histidine kinase activity
L2I54_14245	COG2226	methyltransferase
L2I54_14250	COG2315	Protein conserved in bacteria
L2I54_14295	COG3973	AAA domain
L2I54_14310	COG0514	ATP-dependent DNA helicase (RecQ)
L2I54_14350	COG4637	Psort location Cytoplasmic, score
L2I54_14365	COG3397	chitin binding
L2I54_14380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2I54_14385	COG1115	amino acid carrier protein
L2I54_14390	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_14395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2I54_14405	COG3938	Belongs to the proline racemase family
L2I54_14410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2I54_14450	COG1078	dGTPase activity
L2I54_14455	COG0586	Pfam SNARE associated Golgi protein
L2I54_14465	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L2I54_14475	COG4166	transmembrane transport
L2I54_14485	COG4948	Mandelate Racemase Muconate Lactonizing
L2I54_14500	COG0667	Aldo Keto reductase
L2I54_14545	COG5002	protein histidine kinase activity
L2I54_14545	COG3850	Histidine kinase
L2I54_14550	COG0745	RESPONSE REGULATOR receiver
L2I54_14585	COG1164	Oligoendopeptidase f
L2I54_14590	COG1307	EDD domain protein, DegV family
L2I54_14630	COG2814	Major facilitator Superfamily
L2I54_14640	COG1664	Polymer-forming cytoskeletal
L2I54_14645	COG0789	Transcriptional regulator
L2I54_14650	COG4533	DNA binding
L2I54_14655	COG2814	Major facilitator Superfamily
L2I54_14655	COG0477	Major facilitator Superfamily
L2I54_14675	COG2261	transglycosylase associated protein
L2I54_14690	COG2226	methyltransferase
L2I54_14725	COG0436	Aminotransferase
L2I54_14730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L2I54_14755	COG1131	(ABC) transporter
L2I54_14805	COG0628	permease
L2I54_14820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2I54_14825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2I54_14830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2I54_14870	COG2746	aminoglycoside 3-N-acetyltransferase activity
L2I54_14880	COG0697	spore germination
L2I54_14905	COG4912	Dna alkylation repair
L2I54_14910	COG0346	lactoylglutathione lyase activity
L2I54_14925	COG0861	Integral membrane protein TerC family
L2I54_14930	COG1368	sulfuric ester hydrolase activity
L2I54_14935	COG0488	(ABC) transporter
L2I54_14945	COG1033	growth of symbiont in host cell
L2I54_14945	COG2409	Drug exporters of the RND superfamily
L2I54_14950	COG1309	transcriptional regulator
L2I54_14965	COG0287	Prephenate dehydrogenase
L2I54_14980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L2I54_14980	COG1605	Chorismate mutase
L2I54_15030	COG1388	LysM domain
L2I54_15030	COG3584	3D domain protein
L2I54_15040	COG0346	lactoylglutathione lyase activity
L2I54_15070	COG1879	ABC-type sugar transport system periplasmic component
L2I54_15075	COG1172	Belongs to the binding-protein-dependent transport system permease family
L2I54_15080	COG1172	Belongs to the binding-protein-dependent transport system permease family
L2I54_15090	COG2390	Transcriptional regulator
L2I54_15095	COG1070	Carbohydrate kinase
L2I54_15115	COG2329	Antibiotic biosynthesis monooxygenase
L2I54_15135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_15150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L2I54_15155	COG4187	Peptidase family M20/M25/M40
L2I54_15160	COG1414	Transcriptional regulator
L2I54_15165	COG0833	amino acid
L2I54_15175	COG3239	Fatty acid desaturase
L2I54_15185	COG2720	vancomycin resistance protein
L2I54_15190	COG1785	Belongs to the alkaline phosphatase family
L2I54_15200	COG3655	Transcriptional regulator
L2I54_15220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_15225	COG0346	lactoylglutathione lyase activity
L2I54_15250	COG0714	Associated with various cellular activities
L2I54_15275	COG0463	Glycosyl transferase, family 2
L2I54_15320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2I54_15325	COG0753	catalase activity
L2I54_15365	COG0714	Associated with various cellular activities
L2I54_15435	COG0778	Nitroreductase
L2I54_15440	COG1846	Transcriptional regulator
L2I54_15485	COG0456	acetyltransferase
L2I54_15505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_15560	COG0730	response to heat
L2I54_15570	COG0833	amino acid
L2I54_15580	COG4335	DNA alkylation repair
L2I54_15610	COG0768	penicillin binding
L2I54_15645	COG1984	allophanate hydrolase subunit 2
L2I54_15650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L2I54_15655	COG1414	Transcriptional regulator
L2I54_15670	COG0640	Transcriptional regulator
L2I54_15680	COG1960	acyl-CoA dehydrogenase activity
L2I54_15715	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
L2I54_15735	COG3848	Pyruvate phosphate dikinase
L2I54_15735	COG0574	Belongs to the PEP-utilizing enzyme family
L2I54_15745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_15760	COG5577	PFAM Coat F domain
L2I54_15765	COG3403	YqcI/YcgG family
L2I54_15770	COG1280	lysine exporter protein (LysE YggA)
L2I54_15775	COG1113	amino acid transport
L2I54_15805	COG1063	alcohol dehydrogenase
L2I54_15815	COG1027	Aspartate ammonia-lyase
L2I54_15820	COG0252	asparaginase activity
L2I54_15825	COG1396	sequence-specific DNA binding
L2I54_15855	COG5002	protein histidine kinase activity
L2I54_15885	COG2207	Transcriptional regulator
L2I54_15900	COG0322	excinuclease ABC activity
L2I54_15905	COG0531	amino acid
L2I54_15910	COG1114	Component of the transport system for branched-chain amino acids
L2I54_15915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L2I54_15925	COG0281	malic enzyme
L2I54_15940	COG0531	amino acid
L2I54_15945	COG0697	spore germination
L2I54_15950	COG0784	Response regulator, receiver
L2I54_15955	COG4191	Histidine kinase
L2I54_15965	COG1115	amino acid carrier protein
L2I54_16000	COG0737	Belongs to the 5'-nucleotidase family
L2I54_16005	COG2267	carboxylic ester hydrolase activity
L2I54_16010	COG1335	isochorismatase
L2I54_16030	COG0583	DNA-binding transcription factor activity
L2I54_16035	COG1846	Transcriptional regulator
L2I54_16040	COG0598	Magnesium transport protein CorA
L2I54_16060	COG1073	alpha beta
L2I54_16080	COG0415	Belongs to the DNA photolyase family
L2I54_16095	COG0288	reversible hydration of carbon dioxide
L2I54_16105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2I54_16110	COG5609	conserved protein (DUF2294)
L2I54_16125	COG0697	spore germination
L2I54_16135	COG0456	acetyltransferase
L2I54_16140	COG1575	Belongs to the MenA family. Type 1 subfamily
L2I54_16165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_16175	COG0798	PFAM Bile acid sodium symporter
L2I54_16180	COG0346	lactoylglutathione lyase activity
L2I54_16185	COG0640	Transcriptional regulator
L2I54_16195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2I54_16200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2I54_16200	COG3320	Male sterility
L2I54_16205	COG1309	transcriptional regulator
L2I54_16210	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_16215	COG1522	sequence-specific DNA binding
L2I54_16230	COG0346	lactoylglutathione lyase activity
L2I54_16275	COG0814	amino acid
L2I54_16290	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_16290	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_16295	COG0583	DNA-binding transcription factor activity
L2I54_16320	COG1131	(ABC) transporter
L2I54_16325	COG1725	Transcriptional regulator
L2I54_16360	COG0745	RESPONSE REGULATOR receiver
L2I54_16365	COG5002	protein histidine kinase activity
L2I54_16365	COG3850	Histidine kinase
L2I54_16390	COG2814	Major facilitator Superfamily
L2I54_16410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2I54_16425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L2I54_16440	COG0577	efflux transmembrane transporter activity
L2I54_16460	COG3850	Histidine kinase
L2I54_16460	COG5002	protein histidine kinase activity
L2I54_16470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_16480	COG1619	proteins homologs of microcin C7 resistance protein MccF
L2I54_16495	COG0561	phosphatase activity
L2I54_16505	COG1609	Transcriptional regulator
L2I54_16510	COG0457	Tetratricopeptide repeat
L2I54_16540	COG0534	Mate efflux family protein
L2I54_16560	COG2814	Major facilitator Superfamily
L2I54_16565	COG1309	transcriptional regulator
L2I54_16580	COG1522	sequence-specific DNA binding
L2I54_16585	COG0531	amino acid
L2I54_16600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2I54_16620	COG0662	Cupin 2, conserved barrel domain protein
L2I54_16625	COG2207	Transcriptional regulator
L2I54_16625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_16645	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_16645	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_16770	COG1876	peptidase activity
L2I54_16775	COG2843	Capsule synthesis protein
L2I54_16785	COG0477	Major facilitator Superfamily
L2I54_16800	COG1846	Transcriptional regulator
L2I54_16805	COG2814	Major facilitator Superfamily
L2I54_16815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L2I54_16820	COG1131	(ABC) transporter
L2I54_16840	COG2031	fatty acid transporter
L2I54_16850	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2I54_16905	COG1288	antiporter activity
L2I54_16910	COG2356	endonuclease I
L2I54_16915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2I54_16935	COG1733	regulation of RNA biosynthetic process
L2I54_16940	COG0778	Nitroreductase
L2I54_16970	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_16980	COG1131	(ABC) transporter
L2I54_17005	COG1011	Hydrolase
L2I54_17015	COG2365	Tyrosine phosphatase family
L2I54_17050	COG0628	permease
L2I54_17120	COG1253	flavin adenine dinucleotide binding
L2I54_17125	COG0789	Transcriptional regulator
L2I54_17135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2I54_17160	COG0697	spore germination
L2I54_17170	COG1357	PFAM Pentapeptide repeats (8 copies)
L2I54_17175	COG3813	Protein conserved in bacteria
L2I54_17180	COG2706	6-phosphogluconolactonase activity
L2I54_17185	COG1070	Carbohydrate kinase
L2I54_17200	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L2I54_17205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2I54_17210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L2I54_17220	COG0604	alcohol dehydrogenase
L2I54_17225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2I54_17235	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_17250	COG0656	L-ascorbic acid biosynthetic process
L2I54_17255	COG2814	Major facilitator Superfamily
L2I54_17280	COG0814	amino acid
L2I54_17310	COG1733	regulation of RNA biosynthetic process
L2I54_17315	COG2188	Transcriptional regulator
L2I54_17320	COG0673	inositol 2-dehydrogenase activity
L2I54_17325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L2I54_17330	COG1733	regulation of RNA biosynthetic process
L2I54_17335	COG1733	regulation of RNA biosynthetic process
L2I54_17360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_17380	COG0384	phenazine biosynthesis protein PhzF
L2I54_17410	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2I54_17415	COG1733	regulation of RNA biosynthetic process
L2I54_17420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2I54_17450	COG1191	sigma factor activity
L2I54_17510	COG1151	hydroxylamine reductase activity
L2I54_17545	COG2072	flavoprotein involved in K transport
L2I54_17580	COG1113	amino acid transport
L2I54_17585	COG2814	Major facilitator Superfamily
L2I54_17615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L2I54_17620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L2I54_17630	COG1247	-acetyltransferase
L2I54_17635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_17640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_17645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_17650	COG3739	integral membrane protein
L2I54_17670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_17685	COG0583	DNA-binding transcription factor activity
L2I54_17705	COG1193	negative regulation of DNA recombination
L2I54_17720	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L2I54_17725	COG1164	Oligoendopeptidase f
L2I54_17750	COG3781	membrane
L2I54_17765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2I54_17790	COG0584	glycerophosphoryl diester phosphodiesterase
L2I54_17800	COG0640	Transcriptional regulator
L2I54_17805	COG0604	alcohol dehydrogenase
L2I54_17815	COG0457	Tetratricopeptide repeat
L2I54_17830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2I54_17845	COG0277	FAD linked oxidase domain protein
L2I54_17875	COG3852	Histidine kinase
L2I54_17885	COG1285	pathogenesis
L2I54_17895	COG2514	catechol 2,3-dioxygenase activity
L2I54_17900	COG2720	vancomycin resistance protein
L2I54_17935	COG0716	FMN binding
L2I54_17945	COG0494	nUDIX hydrolase
L2I54_17965	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_17975	COG0165	Argininosuccinate lyase
L2I54_17990	COG4145	pantothenate transmembrane transporter activity
L2I54_18000	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_18005	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_18015	COG1657	PFAM Prenyltransferase squalene oxidase
L2I54_18020	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L2I54_18025	COG2962	Rard protein
L2I54_18030	COG3326	Membrane
L2I54_18045	COG0489	protein tyrosine kinase activity
L2I54_18055	COG0314	molybdopterin synthase activity
L2I54_18060	COG0303	'Molybdopterin
L2I54_18065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L2I54_18070	COG2116	formate transmembrane transporter activity
L2I54_18080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2I54_18085	COG5609	conserved protein (DUF2294)
L2I54_18090	COG2427	Protein of unknown function (DUF1641)
L2I54_18095	COG3383	formate dehydrogenase (NAD+) activity
L2I54_18100	COG0697	spore germination
L2I54_18115	COG0531	amino acid
L2I54_18150	COG2226	methyltransferase
L2I54_18155	COG4166	transmembrane transport
L2I54_18160	COG4166	transmembrane transport
L2I54_18165	COG4166	transmembrane transport
L2I54_18175	COG1316	TRANSCRIPTIONal
L2I54_18185	COG1595	DNA-templated transcription, initiation
L2I54_18195	COG1131	(ABC) transporter
L2I54_18215	COG0673	inositol 2-dehydrogenase activity
L2I54_18220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L2I54_18225	COG0187	DNA topoisomerase II activity
L2I54_18230	COG1832	CoA-binding protein
L2I54_18235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2I54_18240	COG0745	RESPONSE REGULATOR receiver
L2I54_18260	COG4841	protein insertion into membrane
L2I54_18265	COG0824	Thioesterase
L2I54_18300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L2I54_18310	COG1122	ATPase activity
L2I54_18315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2I54_18345	COG2211	Major facilitator Superfamily
L2I54_18355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L2I54_18370	COG0183	Belongs to the thiolase family
L2I54_18375	COG0318	PFAM AMP-dependent synthetase and ligase
L2I54_18380	COG1268	BioY protein
L2I54_18385	COG0318	PFAM AMP-dependent synthetase and ligase
L2I54_18435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_18445	COG5002	protein histidine kinase activity
L2I54_18450	COG0400	carboxylic ester hydrolase activity
L2I54_18455	COG0346	lactoylglutathione lyase activity
L2I54_18460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2I54_18465	COG0069	glutamate synthase activity
L2I54_18470	COG1902	pentaerythritol trinitrate reductase activity
L2I54_18475	COG1329	Transcriptional regulator
L2I54_18480	COG0010	Belongs to the arginase family
L2I54_18530	COG4846	Membrane protein involved in cytochrome C biogenesis
L2I54_18535	COG0785	Cytochrome C biogenesis protein
L2I54_18545	COG1473	amidohydrolase
L2I54_18555	COG1131	(ABC) transporter
L2I54_18570	COG0583	DNA-binding transcription factor activity
L2I54_18580	COG1346	cytolysis
L2I54_18595	COG0730	response to heat
L2I54_18620	COG1132	(ABC) transporter
L2I54_18625	COG1132	(ABC) transporter
L2I54_18650	COG3639	organic phosphonate transmembrane transporter activity
L2I54_18660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2I54_18665	COG0737	Belongs to the 5'-nucleotidase family
L2I54_18675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2I54_18695	COG1695	Transcriptional regulator
L2I54_18705	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_18705	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_18705	COG1388	LysM domain
L2I54_18710	COG0739	heme binding
L2I54_18715	COG0741	lytic transglycosylase activity
L2I54_18745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2I54_18750	COG0174	glutamine synthetase
L2I54_18755	COG0789	Transcriptional regulator
L2I54_18760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L2I54_18765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2I54_18770	COG2860	membrane
L2I54_18780	COG0464	growth
L2I54_18815	COG3584	3D domain protein
L2I54_18815	COG1388	LysM domain
L2I54_18820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2I54_18820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2I54_18820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2I54_18825	COG1105	Belongs to the carbohydrate kinase PfkB family
L2I54_18830	COG1349	DNA-binding transcription factor activity
L2I54_18835	COG1979	alcohol dehydrogenase
L2I54_18840	COG2322	membrane
L2I54_18850	COG1113	amino acid transport
L2I54_18860	COG1408	metallophosphoesterase
L2I54_18865	COG2116	formate transmembrane transporter activity
L2I54_18880	COG2217	Heavy metal translocating P-type atpase
L2I54_18885	COG2608	mercury ion transmembrane transporter activity
L2I54_18890	COG1937	Protein conserved in bacteria
L2I54_18900	COG2819	hydrolase of the alpha beta superfamily
L2I54_18905	COG1120	ATPase activity
L2I54_18910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_18915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_18920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_18925	COG0708	Exodeoxyribonuclease III
L2I54_18930	COG2169	Transcriptional regulator
L2I54_18935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2I54_18940	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L2I54_18960	COG2267	carboxylic ester hydrolase activity
L2I54_18965	COG3300	MHYT domain
L2I54_18965	COG5001	Diguanylate cyclase
L2I54_18985	COG1086	Polysaccharide biosynthesis protein
L2I54_19005	COG1346	cytolysis
L2I54_19015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2I54_19030	COG0823	Involved in the tonB-independent uptake of proteins
L2I54_19040	COG3773	Cell wall hydrolase
L2I54_19050	COG1368	sulfuric ester hydrolase activity
L2I54_19055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L2I54_19085	COG4550	Control of competence regulator ComK, YlbF/YmcA
L2I54_19095	COG1013	pyruvate-flavodoxin oxidoreductase activity
L2I54_19100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L2I54_19100	COG0674	pyruvate-flavodoxin oxidoreductase activity
L2I54_19110	COG2359	stage V sporulation protein S
L2I54_19115	COG1692	metallophosphoesterase
L2I54_19135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2I54_19140	COG1426	Protein conserved in bacteria
L2I54_19155	COG0300	oxidoreductase activity
L2I54_19160	COG0612	Peptidase, M16
L2I54_19165	COG0612	Peptidase, M16
L2I54_19170	COG1079	Belongs to the binding-protein-dependent transport system permease family
L2I54_19175	COG4603	Belongs to the binding-protein-dependent transport system permease family
L2I54_19180	COG3845	ABC transporter
L2I54_19185	COG1744	ABC transporter substrate-binding protein PnrA-like
L2I54_19190	COG2188	Transcriptional regulator
L2I54_19205	COG0740	serine-type endopeptidase activity
L2I54_19210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L2I54_19220	COG0527	aspartate kinase activity
L2I54_19225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L2I54_19230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2I54_19235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L2I54_19240	COG1873	PFAM PRC-barrel domain
L2I54_19245	COG0612	Peptidase, M16
L2I54_19250	COG0726	polysaccharide deacetylase
L2I54_19265	COG0196	riboflavin kinase activity
L2I54_19275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L2I54_19280	COG1550	Protein conserved in bacteria
L2I54_19290	COG1358	cellular component organization or biogenesis
L2I54_19295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L2I54_19300	COG0195	Participates in both transcription termination and antitermination
L2I54_19320	COG0750	zinc metalloprotease
L2I54_19330	COG4589	Belongs to the CDS family
L2I54_19375	COG4974	Belongs to the 'phage' integrase family
L2I54_19385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L2I54_19390	COG0758	DNA mediated transformation
L2I54_19395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L2I54_19435	COG1837	Belongs to the UPF0109 family
L2I54_19445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2I54_19455	COG0552	protein localization to endoplasmic reticulum
L2I54_19460	COG1196	nuclear chromosome segregation
L2I54_19470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2I54_19475	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_19480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2I54_19495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2I54_19500	COG1461	Dihydroxyacetone kinase
L2I54_19505	COG1302	Protein conserved in bacteria
L2I54_19520	COG1564	THIamine pyrophosphokinase
L2I54_19525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2I54_19535	COG0515	serine threonine protein kinase
L2I54_19535	COG2815	serine threonine protein kinase
L2I54_19540	COG0631	protein serine/threonine phosphatase activity
L2I54_19550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L2I54_19550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L2I54_19565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2I54_19570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2I54_19590	COG1561	YicC-like family, N-terminal region
L2I54_19595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2I54_19610	COG0006	proline dipeptidase activity
L2I54_19630	COG3069	C4-dicarboxylate transmembrane transporter activity
L2I54_19695	COG0564	pseudouridine synthase activity
L2I54_19715	COG3599	regulation of cell shape
L2I54_19720	COG2302	S4 RNA-binding domain
L2I54_19725	COG0762	integral membrane protein
L2I54_19735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L2I54_19745	COG1873	PFAM PRC-barrel domain
L2I54_19750	COG1191	sigma factor activity
L2I54_19755	COG1191	sigma factor activity
L2I54_19765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2I54_19770	COG0849	cell division
L2I54_19790	COG0772	Belongs to the SEDS family
L2I54_19810	COG0768	penicillin binding
L2I54_19815	COG0768	penicillin binding
L2I54_19835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L2I54_19850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L2I54_19855	COG1399	metal-binding, possibly nucleic acid-binding protein
L2I54_19865	COG3480	Lon protease (S16) C-terminal proteolytic domain
L2I54_19870	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2I54_19875	COG3314	Sporulation integral membrane protein YlbJ
L2I54_19885	COG0742	ribosomal rna small subunit methyltransferase
L2I54_19900	COG3679	Belongs to the UPF0342 family
L2I54_19905	COG0406	alpha-ribazole phosphatase activity
L2I54_19920	COG2340	Cysteine-rich secretory protein family
L2I54_19935	COG3336	cytochrome c oxidase
L2I54_19970	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L2I54_19975	COG0772	Belongs to the SEDS family
L2I54_19985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L2I54_19990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L2I54_20000	COG4896	Protein conserved in bacteria
L2I54_20015	COG1217	gtp-binding protein TYPA
L2I54_20025	COG0483	inositol monophosphate 1-phosphatase activity
L2I54_20045	COG1982	Orn Lys Arg decarboxylase major
L2I54_20095	COG0022	dehydrogenase e1 component
L2I54_20100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2I54_20115	COG0561	phosphatase activity
L2I54_20125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L2I54_20130	COG0569	domain protein
L2I54_20150	COG0583	DNA-binding transcription factor activity
L2I54_20155	COG0517	IMP dehydrogenase activity
L2I54_20165	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L2I54_20175	COG4703	Protein of unknown function (DUF1797)
L2I54_20190	COG2200	EAL domain
L2I54_20195	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_20200	COG1408	metallophosphoesterase
L2I54_20245	COG2814	Major facilitator Superfamily
L2I54_20265	COG3209	COG3209 Rhs family protein
L2I54_20275	COG2205	protein histidine kinase activity
L2I54_20285	COG0436	Aminotransferase
L2I54_20290	COG1609	Transcriptional regulator
L2I54_20295	COG3833	ABC-type maltose transport systems, permease component
L2I54_20300	COG1175	transmembrane transport
L2I54_20305	COG2182	Extracellular solute-binding protein
L2I54_20315	COG0366	Alpha amylase catalytic
L2I54_20320	COG3842	ATPase activity
L2I54_20360	COG0183	Belongs to the thiolase family
L2I54_20395	COG1695	Transcriptional regulator
L2I54_20400	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_20420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2I54_20425	COG0436	Aminotransferase
L2I54_20460	COG2084	Dehydrogenase
L2I54_20470	COG2199	diguanylate cyclase activity
L2I54_20475	COG0778	Nitroreductase
L2I54_20500	COG1263	PTS System
L2I54_20500	COG2190	(PTS) system
L2I54_20500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L2I54_20505	COG3711	transcriptional antiterminator
L2I54_20515	COG2188	Transcriptional regulator
L2I54_20530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L2I54_20555	COG1547	Domain of unknown function (DUF309)
L2I54_20560	COG0456	acetyltransferase
L2I54_20565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2I54_20570	COG4086	secreted protein
L2I54_20575	COG0561	phosphatase activity
L2I54_20580	COG0697	spore germination
L2I54_20595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L2I54_20620	COG0733	neurotransmitter:sodium symporter activity
L2I54_20640	COG1686	Belongs to the peptidase S11 family
L2I54_20645	COG1725	Transcriptional regulator
L2I54_20650	COG1131	(ABC) transporter
L2I54_20670	COG1846	Transcriptional regulator
L2I54_20685	COG0598	Magnesium transport protein CorA
L2I54_20710	COG4974	Belongs to the 'phage' integrase family
L2I54_20720	COG0735	belongs to the Fur family
L2I54_20725	COG1300	Membrane
L2I54_20745	COG0667	Aldo Keto reductase
L2I54_20750	COG0656	L-ascorbic acid biosynthetic process
L2I54_20755	COG0456	acetyltransferase
L2I54_20755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2I54_20765	COG0737	Belongs to the 5'-nucleotidase family
L2I54_20765	COG4085	toxin activity
L2I54_20765	COG1525	nuclease
L2I54_20775	COG0596	Alpha beta hydrolase
L2I54_20780	COG2056	Na+-H+ antiporter family
L2I54_20785	COG1609	Transcriptional regulator
L2I54_20790	COG0456	acetyltransferase
L2I54_20795	COG1073	alpha beta
L2I54_20810	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2I54_20810	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2I54_20845	COG2226	methyltransferase
L2I54_20845	COG1073	alpha beta
L2I54_20860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L2I54_20870	COG1757	Na H antiporter
L2I54_20875	COG0737	Belongs to the 5'-nucleotidase family
L2I54_20885	COG1522	sequence-specific DNA binding
L2I54_20930	COG0300	oxidoreductase activity
L2I54_20935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_20940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L2I54_20945	COG1760	l-serine dehydratase
L2I54_20950	COG1760	l-serine dehydratase
L2I54_20990	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2I54_20995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_21010	COG1376	ErfK ybiS ycfS ynhG family protein
L2I54_21015	COG4129	membrane
L2I54_21020	COG1126	abc transporter atp-binding protein
L2I54_21025	COG0765	amino acid transport
L2I54_21030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2I54_21055	COG0772	Belongs to the SEDS family
L2I54_21060	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2I54_21065	COG0022	dehydrogenase e1 component
L2I54_21070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2I54_21075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2I54_21090	COG0280	phosphate acetyltransferase
L2I54_21095	COG3290	protein histidine kinase activity
L2I54_21095	COG3829	transcription factor binding
L2I54_21105	COG0584	glycerophosphoryl diester phosphodiesterase
L2I54_21110	COG3093	addiction module antidote protein HigA
L2I54_21125	COG0750	zinc metalloprotease
L2I54_21130	COG0497	DNA recombination
L2I54_21140	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L2I54_21150	COG0142	geranyltranstransferase activity
L2I54_21175	COG1302	Protein conserved in bacteria
L2I54_21180	COG0439	Biotin carboxylase
L2I54_21185	COG0511	ligase activity, forming carbon-carbon bonds
L2I54_21230	COG3854	ATPases associated with a variety of cellular activities
L2I54_21255	COG0006	proline dipeptidase activity
L2I54_21270	COG3872	metal-dependent enzyme
L2I54_21280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2I54_21315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_21325	COG1609	Transcriptional regulator
L2I54_21335	COG2076	Multidrug Resistance protein
L2I54_21340	COG2076	Multidrug Resistance protein
L2I54_21370	COG1131	(ABC) transporter
L2I54_21375	COG1725	Transcriptional regulator
L2I54_21405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L2I54_21470	COG1459	type II secretion system
L2I54_21475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2I54_21530	COG0646	methionine synthase
L2I54_21530	COG1410	methionine synthase
L2I54_21535	COG0646	methionine synthase
L2I54_21535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2I54_21540	COG0626	cystathionine gamma-synthase activity
L2I54_21545	COG0626	cystathionine gamma-synthase activity
L2I54_21565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_21575	COG1940	carbohydrate kinase activity
L2I54_21580	COG4483	Protein conserved in bacteria
L2I54_21585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2I54_21590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L2I54_21595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2I54_21600	COG0704	Plays a role in the regulation of phosphate uptake
L2I54_21610	COG0573	inorganic phosphate transmembrane transporter activity
L2I54_21615	COG0573	inorganic phosphate transmembrane transporter activity
L2I54_21620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L2I54_21625	COG0768	penicillin binding
L2I54_21630	COG0477	Major facilitator Superfamily
L2I54_21635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2I54_21645	COG5521	maltodextrose utilization protein MalA
L2I54_21660	COG0735	belongs to the Fur family
L2I54_21665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2I54_21670	COG1121	(ABC) transporter
L2I54_21675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_21705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2I54_21710	COG2384	SAM-dependent methyltransferase
L2I54_21720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L2I54_21725	COG0358	DNA primase activity
L2I54_21740	COG0517	IMP dehydrogenase activity
L2I54_21755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2I54_21760	COG0295	cytidine deaminase activity
L2I54_21765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L2I54_21775	COG1480	7TM receptor with intracellular HD hydrolase
L2I54_21780	COG1702	phosphate starvation-inducible protein PhoH
L2I54_21795	COG1610	YqeY-like protein
L2I54_21800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L2I54_21805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L2I54_21810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2I54_21840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2I54_21845	COG1733	regulation of RNA biosynthetic process
L2I54_21870	COG1466	dna polymerase III delta subunit
L2I54_21880	COG0658	competence protein
L2I54_21880	COG2333	competence protein COMEC
L2I54_21885	COG2131	deaminase
L2I54_21890	COG1596	polysaccharide export
L2I54_21890	COG1555	photosystem II stabilization
L2I54_21895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L2I54_21900	COG2226	methyltransferase
L2I54_21905	COG0799	negative regulation of ribosome biogenesis
L2I54_21910	COG1713	HD superfamily hydrolase involved in NAD metabolism
L2I54_21920	COG1534	Rna-binding protein
L2I54_21930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L2I54_21935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L2I54_21970	COG0778	Nitroreductase
L2I54_21975	COG2357	RelA SpoT domain protein
L2I54_21985	COG1785	Belongs to the alkaline phosphatase family
L2I54_21995	COG2267	carboxylic ester hydrolase activity
L2I54_22035	COG1404	Belongs to the peptidase S8 family
L2I54_22040	COG3186	Phenylalanine-4-hydroxylase
L2I54_22050	COG2514	catechol 2,3-dioxygenase activity
L2I54_22055	COG2259	Doxx family
L2I54_22095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_22105	COG1454	alcohol dehydrogenase
L2I54_22105	COG1012	belongs to the aldehyde dehydrogenase family
L2I54_22110	COG0626	cystathionine gamma-synthase activity
L2I54_22115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2I54_22140	COG0768	penicillin binding
L2I54_22165	COG0826	peptidase U32
L2I54_22170	COG0826	peptidase U32
L2I54_22175	COG4122	O-methyltransferase activity
L2I54_22180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2I54_22210	COG0628	permease
L2I54_22230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2I54_22245	COG1104	cysteine desulfurase activity
L2I54_22250	COG1959	2 iron, 2 sulfur cluster binding
L2I54_22255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2I54_22270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2I54_22295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2I54_22305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2I54_22305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L2I54_22310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L2I54_22315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2I54_22315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2I54_22325	COG2244	polysaccharide biosynthetic process
L2I54_22330	COG2323	membrane
L2I54_22340	COG1862	Preprotein translocase
L2I54_22370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L2I54_22400	COG0157	Belongs to the NadC ModD family
L2I54_22405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L2I54_22410	COG1104	cysteine desulfurase activity
L2I54_22415	COG1827	regulation of RNA biosynthetic process
L2I54_22420	COG2258	MOSC domain
L2I54_22425	COG0077	Prephenate dehydratase
L2I54_22430	COG0577	efflux transmembrane transporter activity
L2I54_22435	COG0577	efflux transmembrane transporter activity
L2I54_22440	COG1136	(ABC) transporter
L2I54_22445	COG5002	protein histidine kinase activity
L2I54_22450	COG0745	RESPONSE REGULATOR receiver
L2I54_22470	COG2868	ribosomal protein
L2I54_22480	COG1530	ribonuclease E activity
L2I54_22485	COG1994	Peptidase M50
L2I54_22490	COG0739	heme binding
L2I54_22495	COG2894	cell division
L2I54_22515	COG1077	Cell shape determining protein MreB Mrl
L2I54_22535	COG0285	dihydrofolate synthase activity
L2I54_22550	COG1388	LysM domain
L2I54_22560	COG0113	porphobilinogen synthase activity
L2I54_22565	COG1587	Uroporphyrinogen-III synthase
L2I54_22575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L2I54_22585	COG1846	Transcriptional regulator
L2I54_22590	COG1764	response to oxidative stress
L2I54_22605	COG1067	ATP-dependent peptidase activity
L2I54_22605	COG0470	DNA polymerase III
L2I54_22650	COG0622	Phosphoesterase
L2I54_22665	COG5401	PFAM Sporulation and spore germination
L2I54_22685	COG1309	transcriptional regulator
L2I54_22695	COG2197	response regulator
L2I54_22700	COG2233	PERMEase
L2I54_22705	COG0402	S-adenosylhomocysteine deaminase activity
L2I54_22710	COG1983	PspC domain protein
L2I54_22715	COG1396	sequence-specific DNA binding
L2I54_22720	COG0697	spore germination
L2I54_22730	COG1959	2 iron, 2 sulfur cluster binding
L2I54_22735	COG1668	transmembrane transport
L2I54_22740	COG4152	abc transporter atp-binding protein
L2I54_22745	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L2I54_22750	COG1360	Flagellar Motor Protein
L2I54_22755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L2I54_22760	COG1876	peptidase activity
L2I54_22765	COG0824	Thioesterase
L2I54_22770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2I54_22775	COG1053	succinate dehydrogenase
L2I54_22780	COG2009	succinate dehydrogenase
L2I54_22785	COG1719	4-vinyl reductase, 4VR
L2I54_22795	COG3118	belongs to the thioredoxin family
L2I54_22800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L2I54_22805	COG2086	electron transfer activity
L2I54_22810	COG1024	Enoyl-CoA hydratase
L2I54_22815	COG1309	transcriptional regulator
L2I54_22820	COG0318	PFAM AMP-dependent synthetase and ligase
L2I54_22850	COG2318	DinB family
L2I54_22880	COG1131	(ABC) transporter
L2I54_22885	COG2205	protein histidine kinase activity
L2I54_22890	COG0745	RESPONSE REGULATOR receiver
L2I54_22900	COG4895	conserved protein (DUF2196)
L2I54_22905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L2I54_22915	COG4509	Sortase family
L2I54_22920	COG1120	ATPase activity
L2I54_22935	COG5386	Cell surface protein
L2I54_22945	COG5386	Cell surface protein
L2I54_22950	COG1114	Component of the transport system for branched-chain amino acids
L2I54_22955	COG1187	pseudouridine synthase activity
L2I54_22965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L2I54_22965	COG1796	DNA polymerase
L2I54_22970	COG1286	toxin biosynthetic process
L2I54_23010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2I54_23020	COG1418	mRNA catabolic process
L2I54_23040	COG2814	Major facilitator Superfamily
L2I54_23045	COG1566	PFAM secretion protein HlyD family protein
L2I54_23050	COG1309	transcriptional regulator
L2I54_23055	COG1363	Peptidase, m42
L2I54_23080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L2I54_23095	COG1484	DNA-dependent DNA replication
L2I54_23100	COG3611	Membrane attachment protein
L2I54_23110	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
L2I54_23115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2I54_23125	COG1971	Probably functions as a manganese efflux pump
L2I54_23135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2I54_23135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L2I54_23140	COG5002	protein histidine kinase activity
L2I54_23145	COG0745	RESPONSE REGULATOR receiver
L2I54_23160	COG0538	isocitrate dehydrogenase activity
L2I54_23165	COG0372	Belongs to the citrate synthase family
L2I54_23175	COG0628	permease
L2I54_23180	COG3030	protein affecting phage T7 exclusion by the F plasmid
L2I54_23205	COG1725	Transcriptional regulator
L2I54_23210	COG0281	malic enzyme
L2I54_23215	COG0587	DNA-directed DNA polymerase activity
L2I54_23230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L2I54_23245	COG4109	DRTGG domain
L2I54_23260	COG0006	proline dipeptidase activity
L2I54_23300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_23305	COG0662	Cupin 2, conserved barrel domain protein
L2I54_23320	COG1028	Short-chain dehydrogenase reductase Sdr
L2I54_23325	COG0589	response to stress
L2I54_23365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_23390	COG0827	DNA restriction-modification system
L2I54_23395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L2I54_23400	COG3874	Sporulation protein YtfJ
L2I54_23415	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L2I54_23425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2I54_23440	COG1104	cysteine desulfurase activity
L2I54_23450	COG0583	DNA-binding transcription factor activity
L2I54_23455	COG0697	spore germination
L2I54_23460	COG1309	transcriptional regulator
L2I54_23465	COG1956	GAF domain-containing protein
L2I54_23470	COG0626	cystathionine gamma-synthase activity
L2I54_23525	COG1595	DNA-templated transcription, initiation
L2I54_23535	COG0110	maltose O-acetyltransferase activity
L2I54_23540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2I54_23545	COG0454	-acetyltransferase
L2I54_23550	COG0517	IMP dehydrogenase activity
L2I54_23555	COG0123	including yeast histone deacetylase and acetoin utilization protein
L2I54_23570	COG0745	RESPONSE REGULATOR receiver
L2I54_23575	COG5002	protein histidine kinase activity
L2I54_23580	COG0666	response to abiotic stimulus
L2I54_23615	COG1609	Transcriptional regulator
L2I54_23620	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L2I54_23620	COG1605	Chorismate mutase
L2I54_23625	COG4851	CamS sex pheromone cAM373 precursor
L2I54_23630	COG3118	belongs to the thioredoxin family
L2I54_23640	COG2309	aminopeptidase activity
L2I54_23665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_23670	COG0697	spore germination
L2I54_23675	COG0789	Transcriptional regulator
L2I54_23690	COG1674	ftsk spoiiie
L2I54_23695	COG1388	LysM domain
L2I54_23695	COG0860	N-Acetylmuramoyl-L-alanine amidase
L2I54_23710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2I54_23720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L2I54_23725	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
L2I54_23730	COG1363	Peptidase, m42
L2I54_23740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_23755	COG0510	thiamine kinase activity
L2I54_23760	COG1523	belongs to the glycosyl hydrolase 13 family
L2I54_23770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L2I54_23775	COG1349	DNA-binding transcription factor activity
L2I54_23780	COG1187	pseudouridine synthase activity
L2I54_23785	COG2244	polysaccharide biosynthetic process
L2I54_23790	COG2081	HI0933 family
L2I54_23795	COG2814	Major facilitator Superfamily
L2I54_23805	COG3832	glyoxalase III activity
L2I54_23825	COG1329	Transcriptional regulator
L2I54_23850	COG0314	molybdopterin synthase activity
L2I54_23855	COG1763	Mo-molybdopterin cofactor biosynthetic process
L2I54_23860	COG0303	'Molybdopterin
L2I54_23870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L2I54_23875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2I54_23895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L2I54_23905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2I54_23945	COG2814	Major facilitator Superfamily
L2I54_23950	COG0475	glutathione-regulated potassium exporter activity
L2I54_23955	COG0490	domain, Protein
L2I54_23960	COG0582	viral genome integration into host DNA
L2I54_23970	COG1136	(ABC) transporter
L2I54_23990	COG1242	4 iron, 4 sulfur cluster binding
L2I54_23995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L2I54_24010	COG1794	racemase activity, acting on amino acids and derivatives
L2I54_24030	COG2267	carboxylic ester hydrolase activity
L2I54_24035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2I54_24040	COG0671	phosphoesterase, PA-phosphatase related
L2I54_24045	COG0438	transferase activity, transferring glycosyl groups
L2I54_24065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L2I54_24110	COG5002	protein histidine kinase activity
L2I54_24115	COG3852	Histidine kinase
L2I54_24120	COG0753	catalase activity
L2I54_24130	COG2267	carboxylic ester hydrolase activity
L2I54_24135	COG1368	sulfuric ester hydrolase activity
L2I54_24160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2I54_24165	COG1116	anion transmembrane transporter activity
L2I54_24170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2I54_24195	COG0494	nUDIX hydrolase
L2I54_24225	COG1854	S-ribosylhomocysteine lyase activity
L2I54_24235	COG0288	reversible hydration of carbon dioxide
L2I54_24240	COG1271	oxidase subunit
L2I54_24245	COG1294	oxidase, subunit
L2I54_24260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_24280	COG1842	Phage shock protein A
L2I54_24310	COG5002	protein histidine kinase activity
L2I54_24315	COG0745	RESPONSE REGULATOR receiver
L2I54_24340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L2I54_24345	COG1597	lipid kinase activity
L2I54_24410	COG0586	Pfam SNARE associated Golgi protein
L2I54_24420	COG0577	efflux transmembrane transporter activity
L2I54_24425	COG1136	(ABC) transporter
L2I54_24430	COG3708	Transcriptional regulator
L2I54_24430	COG2207	Transcriptional regulator
L2I54_24440	COG5658	integral membrane protein
L2I54_24445	COG0640	Transcriptional regulator
L2I54_24450	COG0745	RESPONSE REGULATOR receiver
L2I54_24455	COG2205	protein histidine kinase activity
L2I54_24460	COG0577	efflux transmembrane transporter activity
L2I54_24465	COG0577	efflux transmembrane transporter activity
L2I54_24470	COG1136	(ABC) transporter
L2I54_24475	COG0577	efflux transmembrane transporter activity
L2I54_24490	COG2188	Transcriptional regulator
L2I54_24510	COG3964	amidohydrolase
L2I54_24530	COG4948	Mandelate Racemase Muconate Lactonizing
L2I54_24540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L2I54_24545	COG0596	Alpha beta hydrolase
L2I54_24555	COG1169	isochorismate synthase
L2I54_24560	COG1575	Belongs to the MenA family. Type 1 subfamily
L2I54_24565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2I54_24590	COG0058	SHG alpha-glucan phosphorylase activity
L2I54_24600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L2I54_24720	COG0544	peptidyl-prolyl cis-trans isomerase activity
L2I54_24755	COG1285	pathogenesis
L2I54_24760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2I54_24775	COG2155	Conserved Protein
L2I54_24780	COG1098	S1 RNA binding domain
L2I54_24785	COG0436	Aminotransferase
L2I54_24790	COG1522	sequence-specific DNA binding
L2I54_24795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L2I54_24800	COG2267	carboxylic ester hydrolase activity
L2I54_24810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L2I54_24830	COG5018	Exonuclease
L2I54_24835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L2I54_24855	COG2050	protein possibly involved in aromatic compounds catabolism
L2I54_24865	COG1268	BioY protein
L2I54_24875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2I54_24880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2I54_24895	COG3584	3D domain protein
L2I54_24910	COG1252	NADH dehydrogenase
L2I54_24925	COG3708	Transcriptional regulator
L2I54_24940	COG1683	Conserved Protein
L2I54_24960	COG0316	Belongs to the HesB IscA family
L2I54_24975	COG1252	NADH dehydrogenase
L2I54_24990	COG0390	transport system, permease component
L2I54_24995	COG2824	Alkylphosphonate utilization operon protein PhnA
L2I54_25045	COG4837	Protein of unknown function (DUF1462)
L2I54_25050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L2I54_25060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2I54_25065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2I54_25075	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2I54_25080	COG0647	UMP catabolic process
L2I54_25090	COG2445	Protein of unknown function DUF86
L2I54_25095	COG1494	fructose-1,6-bisphosphatase
L2I54_25110	COG4470	Protein conserved in bacteria
L2I54_25120	COG0789	Transcriptional regulator
L2I54_25125	COG4377	Putative membrane peptidase family (DUF2324)
L2I54_25155	COG0739	heme binding
L2I54_25165	COG3377	Domain of unknown function (DUF1805)
L2I54_25170	COG0737	Belongs to the 5'-nucleotidase family
L2I54_25175	COG0719	Fe-S assembly protein
L2I54_25180	COG0822	iron-sulfur transferase activity
L2I54_25185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2I54_25190	COG0719	Fe-S assembly protein
L2I54_25195	COG0396	ATPase activity
L2I54_25200	COG1464	Belongs to the NlpA lipoprotein family
L2I54_25205	COG1464	Belongs to the NlpA lipoprotein family
L2I54_25210	COG2011	ABC-type metal ion transport system permease component
L2I54_25225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L2I54_25230	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L2I54_25240	COG1393	Belongs to the ArsC family
L2I54_25260	COG0039	L-malate dehydrogenase activity
L2I54_25280	COG1309	transcriptional regulator
L2I54_25285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2I54_25290	COG1960	acyl-CoA dehydrogenase activity
L2I54_25295	COG0183	Belongs to the thiolase family
L2I54_25300	COG1024	Enoyl-CoA hydratase
L2I54_25300	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2I54_25310	COG1686	Belongs to the peptidase S11 family
L2I54_25325	COG0011	TIGRFAM Protein of
L2I54_25330	COG0840	transmembrane signaling receptor activity
L2I54_25345	COG2814	Major facilitator Superfamily
L2I54_25350	COG0531	amino acid
L2I54_25375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L2I54_25410	COG0586	Pfam SNARE associated Golgi protein
L2I54_25420	COG1376	ErfK ybiS ycfS ynhG family protein
L2I54_25425	COG0745	RESPONSE REGULATOR receiver
L2I54_25430	COG5002	protein histidine kinase activity
L2I54_25460	COG0840	transmembrane signaling receptor activity
L2I54_25465	COG2151	metal-sulfur cluster biosynthetic enzyme
L2I54_25470	COG3227	Zinc metalloprotease (Elastase)
L2I54_25490	COG0475	glutathione-regulated potassium exporter activity
L2I54_25495	COG0490	domain, Protein
L2I54_25500	COG1115	amino acid carrier protein
L2I54_25505	COG0783	Belongs to the Dps family
L2I54_25520	COG1611	Belongs to the LOG family
L2I54_25530	COG1528	Iron-storage protein
L2I54_25540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_25545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_25550	COG1115	amino acid carrier protein
L2I54_25555	COG1115	amino acid carrier protein
L2I54_25560	COG2910	NAD(P)H-binding
L2I54_25580	COG0656	L-ascorbic acid biosynthetic process
L2I54_25585	COG2814	Major facilitator Superfamily
L2I54_25590	COG1733	regulation of RNA biosynthetic process
L2I54_25605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2I54_25690	COG1335	isochorismatase
L2I54_25740	COG0557	exoribonuclease II activity
L2I54_25745	COG1647	Serine aminopeptidase, S33
L2I54_25750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L2I54_25755	COG1346	cytolysis
L2I54_25790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2I54_25805	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L2I54_25815	COG1668	transmembrane transport
L2I54_25820	COG4152	abc transporter atp-binding protein
L2I54_25825	COG4585	Histidine kinase
L2I54_25855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L2I54_25870	COG2323	membrane
L2I54_25880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2I54_25890	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L2I54_25900	COG1051	belongs to the nudix hydrolase family
L2I54_25910	COG0492	ferredoxin-NADP+ reductase activity
L2I54_25915	COG0457	Tetratricopeptide repeat
L2I54_25920	COG0110	maltose O-acetyltransferase activity
L2I54_25940	COG1950	PFAM Membrane protein of
L2I54_25945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2I54_25950	COG0556	nucleotide-excision repair
L2I54_25965	COG0789	Transcriptional regulator
L2I54_25995	COG0583	DNA-binding transcription factor activity
L2I54_26005	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2I54_26010	COG0488	(ABC) transporter
L2I54_26020	COG1132	(ABC) transporter
L2I54_26025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2I54_26030	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_26030	COG0793	Belongs to the peptidase S41A family
L2I54_26035	COG2177	Part of the ABC transporter FtsEX involved in
L2I54_26040	COG2884	Cell division ATP-binding protein ftsE
L2I54_26065	COG1131	(ABC) transporter
L2I54_26095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L2I54_26100	COG1278	Cold shock
L2I54_26105	COG1040	competence protein
L2I54_26110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L2I54_26115	COG0791	NLP P60 protein
L2I54_26115	COG1388	LysM domain
L2I54_26120	COG1733	regulation of RNA biosynthetic process
L2I54_26125	COG1307	EDD domain protein, DegV family
L2I54_26130	COG1739	Uncharacterized protein family UPF0029
L2I54_26135	COG1316	TRANSCRIPTIONal
L2I54_26140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2I54_26145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L2I54_26150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2I54_26160	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L2I54_26160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L2I54_26180	COG1486	melibiose metabolic process
L2I54_26185	COG1447	Phosphotransferase system cellobiose-specific component IIA
L2I54_26190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L2I54_26200	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L2I54_26210	COG1447	Phosphotransferase system cellobiose-specific component IIA
L2I54_26220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L2I54_26225	COG1301	dicarboxylic acid transport
L2I54_26240	COG1511	domain protein
L2I54_26245	COG0583	DNA-binding transcription factor activity
L2I54_26250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L2I54_26260	COG1271	oxidase subunit
L2I54_26265	COG1294	oxidase, subunit
L2I54_26270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L2I54_26280	COG1620	l-lactate permease
L2I54_26290	COG2389	metal-binding protein
L2I54_26300	COG1368	sulfuric ester hydrolase activity
L2I54_26310	COG1388	LysM domain
L2I54_26310	COG0791	NLP P60 protein
L2I54_26315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L2I54_26325	COG1215	transferase activity, transferring glycosyl groups
L2I54_26330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2I54_26335	COG1388	LysM domain
L2I54_26335	COG3584	3D domain protein
L2I54_26360	COG4715	Zinc finger, swim domain protein
L2I54_26365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L2I54_26405	COG0577	efflux transmembrane transporter activity
L2I54_26410	COG1136	(ABC) transporter
L2I54_26445	COG5002	protein histidine kinase activity
L2I54_26450	COG0745	RESPONSE REGULATOR receiver
L2I54_26455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2I54_26460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2I54_26470	COG1316	TRANSCRIPTIONal
L2I54_26495	COG0438	transferase activity, transferring glycosyl groups
L2I54_26505	COG0438	transferase activity, transferring glycosyl groups
L2I54_26510	COG0438	transferase activity, transferring glycosyl groups
L2I54_26520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L2I54_26525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L2I54_26530	COG1086	Polysaccharide biosynthesis protein
L2I54_26535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2I54_26540	COG4464	protein tyrosine phosphatase activity
L2I54_26545	COG0489	protein tyrosine kinase activity
L2I54_26550	COG3944	biosynthesis protein
L2I54_26555	COG0489	protein tyrosine kinase activity
L2I54_26570	COG1609	Transcriptional regulator
L2I54_26580	COG0739	heme binding
L2I54_26595	COG3279	Response regulator of the LytR AlgR family
L2I54_26600	COG2385	sporulation resulting in formation of a cellular spore
L2I54_26615	COG4836	Membrane
L2I54_26620	COG1007	ATP synthesis coupled electron transport
L2I54_26625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2I54_26630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2I54_26640	COG0839	Belongs to the complex I subunit 6 family
L2I54_26660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2I54_26675	COG3300	MHYT domain
L2I54_26675	COG5001	Diguanylate cyclase
L2I54_26725	COG0356	it plays a direct role in the translocation of protons across the membrane
L2I54_26760	COG0698	ribose 5-phosphate isomerase
L2I54_26775	COG2259	Doxx family
L2I54_26780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2I54_26795	COG0009	L-threonylcarbamoyladenylate synthase
L2I54_26830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L2I54_26835	COG1494	fructose-1,6-bisphosphatase
L2I54_26855	COG4821	SIS domain
L2I54_26875	COG1960	acyl-CoA dehydrogenase activity
L2I54_26880	COG1960	acyl-CoA dehydrogenase activity
L2I54_26885	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2I54_26890	COG0183	Belongs to the thiolase family
L2I54_26895	COG0247	lactate metabolic process
L2I54_26895	COG2181	nitrate reductase activity
L2I54_26900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2I54_26910	COG5001	Diguanylate cyclase
L2I54_26910	COG3300	MHYT domain
L2I54_26925	COG3227	Zinc metalloprotease (Elastase)
L2I54_26930	COG2197	response regulator
L2I54_26935	COG4585	Histidine kinase
L2I54_26940	COG0842	Transport permease protein
L2I54_26945	COG1131	(ABC) transporter
L2I54_26950	COG0024	Methionine aminopeptidase
L2I54_26960	COG2234	aminopeptidase activity
L2I54_26980	COG1595	DNA-templated transcription, initiation
L2I54_26990	COG4506	Protein conserved in bacteria
L2I54_26995	COG1619	proteins homologs of microcin C7 resistance protein MccF
L2I54_27020	COG2814	Major facilitator Superfamily
L2I54_27025	COG0789	Transcriptional regulator
L2I54_27030	COG0584	glycerophosphoryl diester phosphodiesterase
L2I54_27035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2I54_27045	COG1994	Peptidase M50
L2I54_27055	COG1078	dGTPase activity
L2I54_27060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L2I54_27065	COG1120	ATPase activity
L2I54_27070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_27075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2I54_27095	COG0280	phosphate acetyltransferase
L2I54_27110	COG3773	Cell wall hydrolase
L2I54_27120	COG2363	Small membrane protein
L2I54_27130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2I54_27135	COG2233	PERMEase
L2I54_27140	COG0561	phosphatase activity
L2I54_27145	COG2814	Major facilitator Superfamily
L2I54_27155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L2I54_27160	COG1131	(ABC) transporter
L2I54_27165	COG2755	lipolytic protein G-D-S-L family
L2I54_27170	COG1609	Transcriptional regulator
L2I54_27180	COG0460	homoserine dehydrogenase
L2I54_27190	COG2873	o-acetylhomoserine
L2I54_27200	COG1011	Hydrolase
L2I54_27205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2I54_27215	COG2197	response regulator
L2I54_27220	COG4585	Histidine kinase
L2I54_27220	COG2203	Gaf domain
L2I54_27225	COG0351	phosphomethylpyrimidine kinase
L2I54_27230	COG3706	GGDEF domain
L2I54_27235	COG2879	small protein
L2I54_27240	COG1966	Carbon starvation protein
L2I54_27245	COG3279	Response regulator of the LytR AlgR family
L2I54_27250	COG0477	Major facilitator Superfamily
L2I54_27260	COG0438	transferase activity, transferring glycosyl groups
L2I54_27275	COG0840	transmembrane signaling receptor activity
L2I54_27285	COG1607	acyl-coa hydrolase
L2I54_27290	COG1216	Glycosyl transferase, family 2
L2I54_27305	COG1216	Glycosyl transferase, family 2
L2I54_27315	COG4485	Bacterial membrane protein, YfhO
L2I54_27320	COG0463	Glycosyl transferase, family 2
L2I54_27325	COG0488	(ABC) transporter
L2I54_27330	COG1309	transcriptional regulator
L2I54_27335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2I54_27340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L2I54_27350	COG0628	permease
L2I54_27375	COG2814	Major facilitator Superfamily
L2I54_27380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2I54_27385	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L2I54_27405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2I54_27410	COG1272	protein, Hemolysin III
L2I54_27430	COG1164	Oligoendopeptidase f
L2I54_27450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2I54_27455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L2I54_27460	COG4853	Protein conserved in bacteria
L2I54_27470	COG5002	protein histidine kinase activity
L2I54_27475	COG0745	RESPONSE REGULATOR receiver
L2I54_27505	COG0305	Participates in initiation and elongation during chromosome replication
L2I54_27515	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L2I54_27520	COG4241	membrane
L2I54_27540	COG0012	GTP binding
L2I54_27545	COG4481	Protein conserved in bacteria
L2I54_27550	COG0668	transmembrane transport
L2I54_27560	COG1475	DNA binding
L2I54_27565	COG1192	Involved in chromosome partitioning
L2I54_27590	COG1847	R3H domain protein
L2I54_27605	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L2I54_27655	COG3620	sequence-specific DNA binding
L2I54_27660	COG0582	viral genome integration into host DNA
L2I54_27675	COG1131	(ABC) transporter
L2I54_27685	COG0582	viral genome integration into host DNA
L2I54_27710	COG0577	efflux transmembrane transporter activity
L2I54_27715	COG1136	(ABC) transporter
L2I54_27770	COG1396	sequence-specific DNA binding
L2I54_27780	COG3561	AntA/AntB antirepressor
L2I54_27825	COG1846	Transcriptional regulator
L2I54_27830	COG1484	DNA-dependent DNA replication
L2I54_27885	COG0756	dUTP diphosphatase activity
L2I54_28115	COG3409	Peptidoglycan-binding domain 1 protein
L2I54_28115	COG1388	LysM domain
L2I54_28115	COG5632	N-Acetylmuramoyl-L-alanine amidase
L2I54_28130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2I54_28145	COG1674	ftsk spoiiie
L2I54_28185	COG1192	Involved in chromosome partitioning