locus-tag class description BA204_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BA204_00015 ENOG410848D S4 domain protein YaaA BA204_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA204_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BA204_00100 ENOG4105ZMH deoxynucleoside kinase BA204_00110 ENOG4105GTG Isochorismatase BA204_00115 ENOG4108Z6B deaminase BA204_00125 ENOG4105C6E dna polymerase iii BA204_00145 ENOG41067KS pro-sigma K processing BA204_00180 ENOG4105CXN decarboxylase BA204_00190 ENOG4105FA2 dna polymerase iii BA204_00195 ENOG4105MA4 psp1 domain protein BA204_00205 ENOG41060K3 Methyltransferase BA204_00215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BA204_00220 ENOG4105KRN Transcriptional regulator, abrb family BA204_00225 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BA204_00230 ENOG4105F8V Hydrolase, tatD family BA204_00235 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BA204_00245 ENOG4105XFA sporulation peptidase YabG BA204_00250 ENOG4105W42 Veg protein BA204_00265 ENOG4105DFT pur operon repressor BA204_00270 ENOG4105KME endoribonuclease L-psp BA204_00285 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BA204_00290 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BA204_00300 ENOG4108JA2 transcriptioN-repair coupling factor BA204_00305 ENOG4108M14 stage v sporulation protein t BA204_00315 ENOG4108IY2 MazG family BA204_00320 ENOG41082I2 s4 domain protein BA204_00325 ENOG4105VYY sporulation protein yabp BA204_00340 ENOG41060GV RNA binding s1 domain protein BA204_00360 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BA204_00365 ENOG4108UGV hypoxanthine phosphoribosyltransferase BA204_00370 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BA204_00385 ENOG4105C6T cysteine synthase BA204_00390 ENOG4105CRQ synthase (Component I) BA204_00395 ENOG4105DDQ anthranilate synthase BA204_00400 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BA204_00405 ENOG4105EEI dihydropteroate synthase BA204_00410 ENOG4105KRF dihydroneopterin aldolase BA204_00415 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BA204_00425 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BA204_00515 ENOG4108Z0C Uvrb UvrC protein BA204_00530 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BA204_00540 ENOG4105CTP PilT protein domain protein BA204_00545 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BA204_00560 ENOG4105D7W serine acetyltransferase BA204_00575 ENOG4105C2N RNA methyltransferase TrmH family group 3 BA204_00580 ENOG4105M0M Tetracycline resistance protein BA204_00585 ENOG4105QIV RNA polymerase BA204_00595 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BA204_00620 ENOG4107Y49 methyltransferase BA204_00635 ENOG4105XPM ribosomal protein BA204_00740 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BA204_00765 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BA204_00775 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BA204_00785 ENOG41067V7 50S ribosomal protein L36 BA204_00810 ENOG4108JJB ABC transporter BA204_00815 ENOG4108JJB ABC transporter BA204_00820 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BA204_00825 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BA204_00850 ENOG4105D1F ATP-binding protein BA204_00865 ENOG4108NMV polysaccharide deacetylase BA204_00945 ENOG4105C8B TIGR00159 family BA204_00950 ENOG4107U5W ybbr family BA204_00965 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BA204_00990 ENOG4108PSK reductase BA204_00995 ENOG4108UMI ABC transporter, permease BA204_01000 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BA204_01005 ENOG4105D01 (LipO)protein BA204_01010 ENOG4105CB2 alcohol dehydrogenase BA204_01020 ENOG4105IQ5 FAD linked oxidase domain protein BA204_01035 ENOG4105C2C drug resistance transporter, Bcr CflA BA204_01065 ENOG4108J59 Extracellular solute-binding protein, family 5 BA204_01070 ENOG4108J59 Extracellular solute-binding protein, family 5 BA204_01090 ENOG4105E0C molybdate abc transporter BA204_01095 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BA204_01100 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BA204_01110 ENOG4105EGI Transcriptional regulator BA204_01130 ENOG4105F6E Acyl-transferase BA204_01150 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BA204_01175 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BA204_01195 ENOG4105C5H ABC transporter BA204_01205 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BA204_01215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA204_01220 ENOG4105C3U ABC transporter BA204_01225 ENOG4108JQ7 (ABC) transporter BA204_01230 ENOG410667J hydrolase BA204_01260 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BA204_01275 ENOG4105CUB amino acid BA204_01280 ENOG4108SC4 )-transporter BA204_01285 ENOG4105CPF Cell wall formation (By similarity) BA204_01290 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BA204_01315 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BA204_01320 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA204_01330 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BA204_01430 ENOG4105K8N protein family UPF0079, ATPase BA204_01435 ENOG41072GX Peptidase M22 Glycoprotease BA204_01440 ENOG410801F ribosomal-protein-alanine acetyltransferase BA204_01445 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BA204_01450 ENOG4105C5H ABC transporter BA204_01465 ENOG4108TYN CAAX amino terminal protease family protein BA204_01485 ENOG4105C7N Xanthine uracil vitamin C permease BA204_01495 ENOG4105BZU Histidine kinase BA204_01520 ENOG4107ZXU DSBA oxidoreductase BA204_01565 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_01600 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BA204_01630 ENOG4105SX7 Transporter BA204_01660 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BA204_01665 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BA204_01670 ENOG4105C83 adenylosuccinate lyase BA204_01680 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BA204_01705 ENOG4108V3E phosphoribosylglycinamide formyltransferase BA204_01715 ENOG4105C12 Phosphoribosylglycinamide synthetase BA204_01740 ENOG4105C4R Atp-dependent dna helicase BA204_01745 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BA204_01765 ENOG4108W2Y isochorismatase BA204_01770 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BA204_01775 ENOG4108UMI ABC transporter, permease BA204_01780 ENOG4105D01 (LipO)protein BA204_01795 ENOG410834F Transcriptional regulator BA204_01800 ENOG4107I77 yiaA/B two helix domain BA204_01820 ENOG4105CBD Diacylglycerol kinase BA204_01825 ENOG4105D7V transposase BA204_01835 ENOG4108JPW Aminotransferase BA204_01845 ENOG4105C26 Dehydrogenase BA204_01850 ENOG4105KPY Small multidrug resistance protein BA204_01875 ENOG4105D9N nucleoside BA204_01880 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BA204_01900 ENOG4108W15 Protein of unknown function (DUF1456) BA204_01915 ENOG4105DTQ mandelate racemase muconate lactonizing BA204_01925 ENOG4105DFD Na H antiporter BA204_01945 ENOG4105D3R alkyl hydroperoxide reductase BA204_01950 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BA204_01955 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BA204_01960 ENOG4107W7X Aldolase BA204_01965 ENOG4105EHG Permease protein BA204_01970 ENOG4105DQ5 transport system permease protein BA204_01975 ENOG4108V5C ABC transporter BA204_01980 ENOG4105CAY ferredoxin--nadp reductase BA204_01995 ENOG4106UIA BA204_02000 ENOG4106UIA BA204_02015 ENOG4105BZU Histidine kinase BA204_02035 ENOG410756H nucleotidyltransferase BA204_02040 ENOG4105D2S major facilitator superfamily BA204_02055 ENOG4105E5Q amino acid AbC transporter BA204_02060 ENOG4105EAB amino acid AbC transporter BA204_02070 ENOG4105C8Q Methyl-accepting chemotaxis BA204_02085 ENOG4105DBV ornithine carbamoyltransferase BA204_02095 ENOG4105C5B carbamate kinase BA204_02100 ENOG4108W63 CRP FNR family transcriptional regulator BA204_02120 ENOG4105CI1 PTS System BA204_02135 ENOG4105C9U ATP-dependent DNA helicase RecQ BA204_02150 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BA204_02170 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BA204_02210 ENOG41062JF Transcriptional regulator BA204_02225 ENOG4105DEU major facilitator superfamily BA204_02240 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BA204_02255 ENOG4108N0M stress protein BA204_02260 ENOG4106FN3 tellurium resistance protein BA204_02265 ENOG4106FN3 tellurium resistance protein BA204_02270 ENOG4107TS3 membrane protein, TerC BA204_02275 ENOG4108TTB tellurium resistance protein BA204_02290 ENOG41068PA UPF0435 protein BA204_02295 ENOG4105KJF protein tyrosine phosphatase BA204_02305 ENOG4107U9T Pfam:Ribonuclease_BN BA204_02310 ENOG4105C59 p-type ATPase BA204_02315 ENOG4108IPJ Membrane BA204_02325 ENOG4105C3F Signal peptidase i BA204_02335 ENOG4107ZTW SNARE associated Golgi BA204_02350 ENOG410606W general stress protein BA204_02355 ENOG4105UPD Calcium Proton BA204_02390 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BA204_02395 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BA204_02405 ENOG4108JUB Transcriptional regulator BA204_02415 ENOG4108IQI permease BA204_02450 ENOG4108A04 Beta-lactamase BA204_02465 ENOG4105CKK Glycosyl transferase, family 2 BA204_02470 ENOG4107QQG Dehydrogenase BA204_02475 ENOG4105C3I Nad-dependent epimerase dehydratase BA204_02495 ENOG4105F1A Pyruvate formate-lyase BA204_02500 ENOG4108QBV Monogalactosyldiacylglycerol synthase BA204_02515 ENOG4105CI2 imidazolone-5-propionate hydrolase BA204_02520 ENOG4105ECP epimerase BA204_02550 ENOG41067AE Membrane-bound metal-dependent hydrolase BA204_02555 ENOG4105CEN a g-specific adenine glycosylase BA204_02560 ENOG4106BXE BA204_02580 ENOG4105BZ1 (ABC) transporter BA204_02585 ENOG4107NBY Membrane BA204_02590 ENOG4105CBC glutamate synthase BA204_02600 ENOG4108IUW ABC transporter BA204_02620 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA204_02625 ENOG4105G5W regulator Fur family BA204_02735 ENOG4105CDY transcriptional regulatory protein BA204_02745 ENOG4108JQC penicillin-binding protein 1A BA204_02750 ENOG4108R9S DSBA oxidoreductase BA204_02760 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BA204_02770 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BA204_02780 ENOG4105CYN Serine protein kinase BA204_02800 ENOG4105C94 Transporter BA204_02815 ENOG4105DZ6 Band 7 protein BA204_02825 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BA204_02835 ENOG4105D4T Citrate transporter BA204_02860 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BA204_02865 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA204_02870 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BA204_02875 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BA204_02880 ENOG4105BZ7 extracellular solute-binding protein family 1 BA204_02885 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BA204_02890 ENOG4108STX response regulator BA204_02895 ENOG4105US7 Histidine kinase BA204_02920 ENOG4108MRH transcriptional regulatory protein BA204_02930 ENOG4105C6K Malic enzyme BA204_02940 ENOG4108UZ3 Transporter BA204_02945 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA204_02955 ENOG4105BZU Histidine kinase BA204_02960 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_02975 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BA204_02980 ENOG4108JB9 formate dehydrogenase BA204_03000 ENOG4105CUB amino acid BA204_03010 ENOG4105C59 p-type ATPase BA204_03015 ENOG4105DAP Nicotinate phosphoribosyltransferase BA204_03045 ENOG41073R8 VanW family BA204_03050 ENOG4108KGH TRANSCRIPTIONal BA204_03055 ENOG4105D9N nucleoside BA204_03060 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BA204_03065 ENOG4105C37 (CBS) domain BA204_03070 ENOG4108IJ0 Aspartate ammonia-lyase BA204_03075 ENOG4105DAA L-lactate BA204_03090 ENOG4105DUX Transporter BA204_03095 ENOG4108MES Periplasmic binding protein BA204_03100 ENOG4105DQ5 transport system permease protein BA204_03105 ENOG4108IHU transport system permease protein BA204_03110 ENOG4105E0A ABC, transporter BA204_03115 ENOG4105DMQ Methyltransferase BA204_03120 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BA204_03125 ENOG4105EXW epimerase dehydratase BA204_03135 ENOG4107T89 von Willebrand factor, type A BA204_03140 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BA204_03145 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA204_03155 ENOG4105BZU Histidine kinase BA204_03160 ENOG4105D5Q Arginine ornithine antiporter BA204_03165 ENOG4107414 GntR family transcriptional regulator BA204_03170 ENOG4105C5Y PTS System BA204_03175 ENOG4105CG3 alpha amylase, catalytic region BA204_03195 ENOG4105CRN Aminoglycoside phosphotransferase BA204_03200 ENOG4105BZG amino acid carrier protein BA204_03210 ENOG4105CDA abc transporter atp-binding protein BA204_03215 ENOG4105CT1 (ABC) transporter BA204_03220 ENOG4105EAD ABC transporter BA204_03225 ENOG4105DRP amino acid AbC transporter BA204_03230 ENOG4108IQI permease BA204_03245 ENOG4105GFR rna polymerase sigma factor BA204_03255 ENOG4105D29 Helix-turn-helix type 11 domain protein BA204_03260 ENOG4105NAE bifunctional deaminase-reductase domain protein BA204_03265 ENOG4105BZU Histidine kinase BA204_03280 ENOG4105CHH sulfate transporter BA204_03285 ENOG41068KF Universal stress protein BA204_03295 ENOG4105CXY transporter BA204_03300 ENOG41067TZ transcriptional regulator, MarR family BA204_03305 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_03310 ENOG4105ETE Transcriptional regulator (LacI family BA204_03315 ENOG4108RVA ribokinase BA204_03325 ENOG4105C2J ABC transporter BA204_03330 ENOG4105CNN ABC, transporter BA204_03335 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BA204_03340 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA204_03375 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BA204_03405 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BA204_03410 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BA204_03415 ENOG41069ER domain protein BA204_03420 ENOG4105VZ8 Transcriptional regulator BA204_03425 ENOG4107D63 BA204_03440 ENOG4105DUX Transporter BA204_03460 ENOG4105C85 amino acid BA204_03465 ENOG4105C7N Xanthine uracil vitamin C permease BA204_03480 ENOG4105MA6 gCN5-related N-acetyltransferase BA204_03500 ENOG4105CCU oxidase (Subunit III) BA204_03505 ENOG4105BZ9 Cytochrome C oxidase, subunit I BA204_03510 ENOG4105E2S oxidase) subunit II BA204_03530 ENOG4106CAD Protein of unknown function (DUF3311) BA204_03535 ENOG4105E1V na solute symporter BA204_03550 ENOG4108NHD germination protein BA204_03555 ENOG4105CE1 Ferrous iron transport protein b BA204_03560 ENOG4105CE1 Ferrous iron transport protein b BA204_03565 ENOG4105CE1 Ferrous iron transport protein b BA204_03570 ENOG4105CVA phosphate BA204_03575 ENOG4105C8U phosphate abc transporter BA204_03580 ENOG4105E2Z phosphate ABC transporter (Permease BA204_03705 ENOG41080XQ Signal transduction protein with cbs domains BA204_03725 ENOG4105ETU transcriptional activator (TenA BA204_03735 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BA204_03745 ENOG4108VEU Thiamine monophosphate synthase BA204_03750 ENOG41080HI glycine oxidase BA204_03765 ENOG4105D06 uba thif-type nad fad binding protein BA204_03770 ENOG4105DWF phosphomethylpyrimidine kinase BA204_03820 ENOG4108INS Transcriptional regulator BA204_03840 ENOG4105C7N Xanthine uracil vitamin C permease BA204_03850 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA204_03870 ENOG4105C5Y PTS System BA204_03885 ENOG4105K63 Thioredoxin BA204_03905 ENOG4108B31 Spore germination protein BA204_03925 ENOG4107Y03 Nitroreductase BA204_03930 ENOG4105ED1 spovr family BA204_03940 ENOG4108TCS Glutamyl endopeptidase BA204_03950 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BA204_03955 ENOG4105XTG Pfam:DUF156 BA204_03960 ENOG4105VFE sira family BA204_03965 ENOG4107TPS domain protein BA204_03970 ENOG4105VFE sira family BA204_03975 ENOG4105VFE sira family BA204_03985 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BA204_03990 ENOG41087NI Sulfite exporter TauE/SafE BA204_04000 ENOG4108KGH TRANSCRIPTIONal BA204_04025 ENOG4105EMD TRANSCRIPTIONal BA204_04030 ENOG4105VCP PTS System BA204_04035 ENOG4105VZJ PTS System BA204_04060 ENOG41069ER domain protein BA204_04065 ENOG4107RBB ABC transporter, permease BA204_04070 ENOG4105C19 ABC transporter BA204_04100 ENOG4105WEF catalase BA204_04135 ENOG4107T5V SNARE associated Golgi BA204_04165 ENOG4105CUB amino acid BA204_04170 ENOG4107RWR Sodium hydrogen exchanger BA204_04180 ENOG4106KNT transcriptional regulator BA204_04220 ENOG4108YXU transcriptional regulator AsnC family BA204_04225 ENOG4105CH7 arginosuccinase BA204_04230 ENOG4108IXY short-chain dehydrogenase reductase BA204_04240 ENOG4105KPY Small multidrug resistance protein BA204_04280 ENOG4105C19 ABC transporter BA204_04285 ENOG4107RBB ABC transporter, permease BA204_04290 ENOG4105C19 ABC transporter BA204_04325 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BA204_04330 ENOG4105E5W Transporter BA204_04340 ENOG4107RKG DJ-1/PfpI family BA204_04345 ENOG4105CH6 catalase BA204_04355 ENOG4105D5Q Arginine ornithine antiporter BA204_04360 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BA204_04370 ENOG4105C26 Dehydrogenase BA204_04375 ENOG4105BZ1 (ABC) transporter BA204_04380 ENOG4105BZ1 (ABC) transporter BA204_04390 ENOG4105DRP amino acid AbC transporter BA204_04395 ENOG4105CDA abc transporter atp-binding protein BA204_04410 ENOG410839P BA204_04445 ENOG4107FQX Alpha-acetolactate decarboxylase BA204_04450 ENOG4108VX5 3-methyladenine DNA glycosylase BA204_04465 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BA204_04470 ENOG4105D4P Coproporphyrinogen iii oxidase BA204_04490 ENOG4105CHH sulfate transporter BA204_04515 ENOG4105CGU Enoyl-CoA hydratase BA204_04535 ENOG4105DER m42 family BA204_04560 ENOG4105CIF Ornithine Cyclodeaminase BA204_04580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA204_04585 ENOG4105C3U ABC transporter BA204_04590 ENOG4108JQ7 (ABC) transporter BA204_04635 ENOG4108IBT Inherit from COG: transposase BA204_04715 ENOG4105CSH Transporter BA204_04725 ENOG4108MRH transcriptional regulatory protein BA204_04735 ENOG4105M6F mutator MutT protein BA204_04750 ENOG4105CDU Replicative dna helicase BA204_04775 ENOG4108Z86 Glutamine amidotransferase BA204_04790 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_04805 ENOG4105D9U N-acetyltransferase BA204_04880 ENOG4105F6J Alpha beta hydrolase fold BA204_04930 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BA204_04950 ENOG4105CMT Dihydroxyacetone kinase BA204_04960 ENOG4105CMT Dihydroxyacetone kinase BA204_05045 ENOG4105WN5 stage II sporulation protein BA204_05055 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_05065 ENOG4108MJI response regulator BA204_05070 ENOG4105BZU Histidine kinase BA204_05075 ENOG4105BZU Histidine kinase BA204_05110 ENOG4107QHE Choloylglycine hydrolase BA204_05130 ENOG4107VRP DNA repair exonuclease BA204_05135 ENOG4106D4I domain protein BA204_05145 ENOG4105ED2 Beta-lactamase BA204_05180 ENOG4108MUZ hydrolase BA204_05200 ENOG4105F0F Oxalate decarboxylase BA204_05210 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BA204_05225 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BA204_05245 ENOG4105EMN RNA polymerase sigma factor BA204_05255 ENOG4105CNI cell division protein FtsW BA204_05270 ENOG4105EEM helicase BA204_05275 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA204_05300 ENOG4105K59 histidine triad (HIT) protein BA204_05330 ENOG410905X membrane-flanked domain protein BA204_05335 ENOG4105CKV Membrane BA204_05375 ENOG410905X membrane-flanked domain protein BA204_05380 ENOG4105CKV Membrane BA204_05385 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BA204_05390 ENOG4105BZ4 penicillin-binding protein BA204_05400 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BA204_05405 ENOG4105C1Q protoporphyrinogen oxidase BA204_05430 ENOG4105NA0 Transcriptional regulator BA204_05445 ENOG4105ECB domain protein BA204_05465 ENOG4108MK9 spermidine N(1)-acetyltransferase BA204_05475 ENOG4106AXD BA204_05480 ENOG4108RQ5 Beta-lactamase domain-containing protein BA204_05485 ENOG4105DF9 Lipoate-protein, ligase BA204_05495 ENOG4105CEY Amp-dependent synthetase and ligase BA204_05505 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BA204_05510 ENOG4108I5D sulfate abc transporter BA204_05520 ENOG4108IJ6 ABC transporter BA204_05525 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BA204_05530 ENOG4107RN3 metallophosphoesterase BA204_05535 ENOG4107TVP HD domain protein BA204_05545 ENOG4108AEY RNA polymerase sigma factor BA204_05550 ENOG41086D8 Transcriptional regulator BA204_05565 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_05585 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BA204_05590 ENOG4105C8Q Methyl-accepting chemotaxis BA204_05595 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BA204_05605 ENOG4107QP3 malate synthase g BA204_05625 ENOG4105VEQ Cold shock protein BA204_05705 ENOG4105ERH Fumarylacetoacetate hydrolase BA204_05715 ENOG4105C8Y Acetylornithine aminotransferase BA204_05730 ENOG4105CAQ asparagine synthetase BA204_05735 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BA204_05740 ENOG4105CH6 catalase BA204_05745 ENOG4105BZU Histidine kinase BA204_05755 ENOG4108VPT UPF0234 protein BA204_05760 ENOG4105QNR S1 RNA binding domain protein BA204_05765 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA204_05775 ENOG4107AYK membrAne BA204_05780 ENOG41073B9 BA204_05790 ENOG4108KP7 hydrolase BA204_05800 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BA204_05825 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BA204_05830 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA204_05845 ENOG4105C31 Tryptophanyl-tRNA synthetase BA204_05860 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA204_05865 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA204_05875 ENOG4108JQ7 (ABC) transporter BA204_05880 ENOG4105UQX Mate efflux family protein BA204_05900 ENOG4108ZCF integral membrane protein BA204_05910 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA204_05920 ENOG4105DPN Oligoendopeptidase f BA204_05930 ENOG4108Z18 K06886 hemoglobin BA204_05935 ENOG4105MIX Adenylate cyclase BA204_05940 ENOG4106EFP UPF0738 protein BA204_05950 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BA204_05955 ENOG4105EMS pseudouridine synthase BA204_05975 ENOG4105K64 Glycosyl transferase, family 2 BA204_05995 ENOG4107TVC Glycosyl transferase, family 2 BA204_06015 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BA204_06020 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BA204_06030 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BA204_06080 ENOG4108ZMI UPF0477 protein BA204_06105 ENOG4105CK7 Sodium proline symporter BA204_06110 ENOG4105CRQ synthase (Component I) BA204_06115 ENOG4105DDQ anthranilate synthase BA204_06125 ENOG4105DK0 Indole-3-glycerol phosphate synthase BA204_06205 ENOG4105C7S Dehydrogenase BA204_06250 ENOG4105CVR type I restriction-modification system BA204_06275 ENOG4108NE4 BA204_06280 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA204_06305 ENOG4105DZ1 carboxypeptidase BA204_06310 ENOG4105VFR signal peptidase BA204_06345 ENOG4105C26 Dehydrogenase BA204_06350 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA204_06355 ENOG4105F38 ABC transporter, permease BA204_06360 ENOG4105D38 putrescine abc transporter BA204_06365 ENOG4107RUE extracellular solute-binding protein family 1 BA204_06375 ENOG4105EYF MMPL domain protein BA204_06385 ENOG4108YBP pseudouridine synthase BA204_06395 ENOG4105K4I Scp-like extracellular BA204_06400 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BA204_06405 ENOG4105CQB FAD linked oxidase domain protein BA204_06420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_06425 ENOG4105BZU Histidine kinase BA204_06430 ENOG4105JXH GntR family transcriptional regulator BA204_06450 ENOG4106A3R peptidase BA204_06460 ENOG4108QTI )-transporter BA204_06465 ENOG4107TS3 membrane protein, TerC BA204_06470 ENOG4105CZN Potassium uptake protein BA204_06475 ENOG410681C small acid-soluble spore protein BA204_06480 ENOG4108Z7G MaoC domain protein dehydratase BA204_06500 ENOG4105CHR reductase BA204_06530 ENOG4105C4Y ABC transporter BA204_06535 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA204_06540 ENOG4107RCV ABC transporter, permease BA204_06560 ENOG4105E98 transcriptional regulator DeoR family BA204_06575 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BA204_06585 ENOG4105PXI polysaccharide deacetylase BA204_06595 ENOG4105BZU Histidine kinase BA204_06600 ENOG41090MY MarR family Transcriptional regulator BA204_06610 ENOG4106DF1 BA204_06620 ENOG4105BZU Histidine kinase BA204_06625 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BA204_06630 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BA204_06635 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BA204_06675 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BA204_06680 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BA204_06695 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BA204_06700 ENOG4105CZV ABC transporter BA204_06710 ENOG4105CJ1 ABC, transporter BA204_06750 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BA204_06755 ENOG4105EA8 2-Nitropropane dioxygenase BA204_06760 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BA204_06770 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BA204_06795 ENOG4105NQC Flavodoxin BA204_06830 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BA204_06860 ENOG4105CZN Potassium uptake protein BA204_06865 ENOG41063Y9 BA204_06870 ENOG4105KBJ sporulation protein ytfj BA204_06890 ENOG4105CM2 brancheD-chain amino acid aminotransferase BA204_06895 ENOG4105C7K acetolactate synthase BA204_06900 ENOG4108ZP8 Acetolactate synthase small subunit BA204_06905 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BA204_06920 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BA204_06935 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BA204_06940 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BA204_06950 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BA204_06955 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BA204_06960 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BA204_06975 ENOG4107RVV histidinol phosphate phosphatase, hisj family BA204_06990 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BA204_06995 ENOG4105E0M Sulfatase BA204_07005 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BA204_07020 ENOG4107S4M Sulfate adenylate transferase BA204_07025 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BA204_07030 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BA204_07040 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BA204_07045 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BA204_07050 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BA204_07055 ENOG4105C8J )-transporter BA204_07075 ENOG4105DFD Na H antiporter BA204_07095 ENOG4105ENE Histidine kinase BA204_07100 ENOG4105WH1 Two component transcriptional regulator luxr family BA204_07120 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BA204_07145 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BA204_07165 ENOG4105CJ3 phosphate transporter BA204_07170 ENOG4107GRR phosphate transport regulator BA204_07175 ENOG4105BZ4 penicillin-binding protein BA204_07190 ENOG4105BZU Histidine kinase BA204_07195 ENOG4105I3N Conserved Protein BA204_07210 ENOG4105BZU Histidine kinase BA204_07240 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA204_07245 ENOG4105DZ1 carboxypeptidase BA204_07250 ENOG4108JIC nucleoside recognition domain protein BA204_07260 ENOG4105FE9 pseudouridine synthase BA204_07265 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA204_07270 ENOG4107TWT Cytochrome c biogenesis protein BA204_07275 ENOG4105CRE cytochrome C BA204_07280 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_07285 ENOG4105BZU Histidine kinase BA204_07290 ENOG4108WBT adenosyltransferase BA204_07305 ENOG4108SAX Membrane BA204_07320 ENOG4105C9U ATP-dependent DNA helicase RecQ BA204_07325 ENOG4105I7S Abortive infection protein BA204_07335 ENOG4107RGJ metallophosphoesterase BA204_07340 ENOG4108XDN Transcriptional regulator BA204_07345 ENOG4108S6Z Negative regulator of genetic competence BA204_07370 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BA204_07375 ENOG4107RB3 L-asparaginase BA204_07390 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BA204_07410 ENOG4105S2F BA204_07415 ENOG41065D1 BA204_07445 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BA204_07460 ENOG4105XXQ heptaprenyl diphosphate synthase component I BA204_07470 ENOG4105EAH synthase BA204_07475 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BA204_07495 ENOG41068YB TPR repeat-containing protein BA204_07510 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BA204_07515 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BA204_07550 ENOG4108JYZ YitT family BA204_07555 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BA204_07570 ENOG4105FJR Lmbe family BA204_07575 ENOG4105CPK Glycosyl transferase (Group 1 BA204_07595 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BA204_07610 ENOG4105DVT helicase BA204_07615 ENOG4105YAC BA204_07635 ENOG4105CSM endonuclease III BA204_07645 ENOG4105BZ4 penicillin-binding protein BA204_07685 ENOG4106F55 Protein of unknown function (DUF1273) BA204_07700 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BA204_07710 ENOG4105DVT helicase BA204_07715 ENOG4105CTD carboxy-peptidase BA204_07725 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BA204_07730 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BA204_07735 ENOG4105C2W permease BA204_07740 ENOG4105DHF Membrane BA204_07745 ENOG410890F Dynamin family BA204_07755 ENOG4108W0I acetyltransferase BA204_07765 ENOG4105KHC sulfurtransferase BA204_07820 ENOG4105HTX biosynthesis protein BA204_07850 ENOG4105CPK Glycosyl transferase (Group 1 BA204_07865 ENOG4108SZE gCN5-related N-acetyltransferase BA204_07885 ENOG41081VK Ribonuclease BA204_07950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA204_07960 ENOG4107RWR Sodium hydrogen exchanger BA204_07965 ENOG4105CN5 Metallo-Beta-Lactamase BA204_07970 ENOG4108Z5V transcriptional regulator, merr family BA204_07980 ENOG4105H67 Protein of unknown function (DUF421) BA204_07985 ENOG41080C8 DUF218 domain BA204_08025 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BA204_08035 ENOG4107R0U MotA TolQ exbB proton channel BA204_08040 ENOG4105ER2 Ompa motb domain protein BA204_08045 ENOG4107YTP response regulator receiver protein BA204_08050 ENOG4105CBS Chea signal transduction histidine kinase BA204_08055 ENOG4105DD5 Flagellar motor switch protein BA204_08070 ENOG4105BZU Histidine kinase BA204_08090 ENOG4105E1Q flagellar hook-associated protein BA204_08095 ENOG4105DTJ flagellar hook-associated protein BA204_08115 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BA204_08120 ENOG4108ZC9 flagellar basal-body rod protein flgc BA204_08125 ENOG41075Z6 flagellar hook-basal body complex protein fliE BA204_08130 ENOG4107U2N Flagellar M-ring protein BA204_08135 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA204_08165 ENOG4105BZE flagellar hook protein, FlgE BA204_08180 ENOG4107R88 Chemotaxis protein (CheV) BA204_08190 ENOG4105I03 Flagellin BA204_08195 ENOG4105I03 Flagellin BA204_08200 ENOG4105E4C Lytic transglycosylase catalytic BA204_08210 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA204_08215 ENOG4105DD5 Flagellar motor switch protein BA204_08225 ENOG4105CN7 Flagellar biosynthetic protein FliP BA204_08230 ENOG4105VS8 Flagellar biosynthetic protein fliq BA204_08240 ENOG4105D00 flagellar biosynthetic protein flhB BA204_08245 ENOG4105D7B Flagellar biosynthesis protein flha BA204_08250 ENOG4105FZW flagellar biosynthesis regulator FlhF BA204_08255 ENOG4105KTQ flagellar basal-body rod protein BA204_08260 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA204_08295 ENOG4105KAC Antibiotic biosynthesis monooxygenase BA204_08320 ENOG4105DUM transcriptional regulator, lysR family BA204_08335 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BA204_08365 ENOG4105CVJ phosphoglycerate mutase BA204_08375 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BA204_08395 ENOG4105CAQ asparagine synthetase BA204_08415 ENOG4105PGM cation diffusion facilitator family transporter BA204_08425 ENOG4105DRR Transcriptional regulator, GntR family BA204_08430 ENOG4108UZ3 Transporter BA204_08440 ENOG4105CKI cobalamin synthesis protein BA204_08445 ENOG4108PJD permease BA204_08460 ENOG4105DFD Na H antiporter BA204_08465 ENOG4105VUF Transcriptional regulator BA204_08475 ENOG4105C9Q fumarate hydratase class II BA204_08490 ENOG4107QJQ Mate efflux family protein BA204_08495 ENOG4105EC3 peptidase S51, dipeptidase E BA204_08515 ENOG4107QIV Cytochrome c biogenesis protein BA204_08520 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA204_08530 ENOG4107JM4 Tetratricopeptide repeat BA204_08550 ENOG4106BRA Membrane BA204_08585 ENOG4105CJ1 ABC, transporter BA204_08610 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BA204_08620 ENOG4108IJ0 Aspartate ammonia-lyase BA204_08625 ENOG4105C6K Malic enzyme BA204_08680 ENOG4105FVX BA204_08695 ENOG4105U3E Transcriptional regulator BA204_08705 ENOG4105DXI Major Facilitator superfamily BA204_08715 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BA204_08720 ENOG4105EU0 Major facilitator Superfamily BA204_08725 ENOG4105C6T cysteine synthase BA204_08745 ENOG4105C8J )-transporter BA204_08755 ENOG4105X5K response regulator receiver protein BA204_08760 ENOG4105H67 Protein of unknown function (DUF421) BA204_08785 ENOG4105CHR reductase BA204_08790 ENOG4105CM2 brancheD-chain amino acid aminotransferase BA204_08795 ENOG4105C7K acetolactate synthase BA204_08805 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BA204_08810 ENOG4105C01 Dihydroxy-acid dehydratase BA204_08815 ENOG4105C7B Threonine dehydratase BA204_08840 ENOG4105C6X Major Facilitator BA204_08845 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BA204_08855 ENOG4105DY9 regulatoR BA204_08860 ENOG4105CYC Transferase BA204_08865 ENOG4105K5X acetyltransferase BA204_08885 ENOG41068WN BA204_08890 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_08905 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BA204_08920 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BA204_08930 ENOG4105C0X amino acid BA204_08955 ENOG4105K8R UPF0145 protein BA204_08970 ENOG4107RHR regulatoR BA204_08980 ENOG4105D9N nucleoside BA204_08985 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BA204_09025 ENOG4107RAQ aminopeptidase BA204_09035 ENOG4107R16 Multicopper oxidase BA204_09075 ENOG4108T5E Copper resistance protein BA204_09080 ENOG4105KTB nuclear export factor GLE1 BA204_09085 ENOG4107RT3 EamA-like transporter family BA204_09090 ENOG4105GZI Transcriptional regulator BA204_09095 ENOG4108Z40 Transcriptional regulator BA204_09100 ENOG4107ZXU DSBA oxidoreductase BA204_09105 ENOG4108TVJ Nitroreductase BA204_09115 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BA204_09120 ENOG4106F5Q Membrane BA204_09125 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BA204_09135 ENOG4105CKI cobalamin synthesis protein BA204_09145 ENOG4105C0Z ABC transporter BA204_09150 ENOG4108IV0 ABC, transporter BA204_09155 ENOG4105C32 Amino acid ABC transporter (Permease) BA204_09165 ENOG4105SKE transcriptional Regulator LysR family BA204_09195 ENOG4105C4M (Ubiquinol oxidase) subunit I BA204_09200 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA204_09205 ENOG4108JJ9 ABC, transporter BA204_09210 ENOG4108JJ8 (ABC) transporter BA204_09220 ENOG4105K64 Glycosyl transferase, family 2 BA204_09230 ENOG4108UT6 Transferase hexapeptide repeat containing protein BA204_09285 ENOG4105BZ1 (ABC) transporter BA204_09290 ENOG4105EFI regulatoR BA204_09295 ENOG4105BZU Histidine kinase BA204_09305 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BA204_09310 ENOG4108ZJ4 polysaccharide deacetylase BA204_09330 ENOG4105D6E homoserine dehydrogenase BA204_09340 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BA204_09355 ENOG4108KGH TRANSCRIPTIONal BA204_09365 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_09370 ENOG4105BZU Histidine kinase BA204_09375 ENOG4107VMI polysaccharide deacetylase BA204_09385 ENOG4105KT7 mgtC SapB transporter BA204_09390 ENOG4105VRR gCN5-related N-acetyltransferase BA204_09400 ENOG4105DUU IucA IucC family protein BA204_09405 ENOG4105CEY Amp-dependent synthetase and ligase BA204_09420 ENOG4108WBH protein TIM barrel BA204_09425 ENOG4105YWU small acid-soluble spore protein BA204_09435 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BA204_09440 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA204_09490 ENOG4105KRN Transcriptional regulator, abrb family BA204_09530 ENOG4105C8Q Methyl-accepting chemotaxis BA204_09545 ENOG4108K88 Membrane BA204_09550 ENOG4108WPJ Ferritin-like domain BA204_09565 ENOG4105DEN Luciferase family BA204_09580 ENOG4105VMI -acetyltransferase BA204_09585 ENOG4107QM2 Aldo Keto reductase BA204_09590 ENOG4105CKI cobalamin synthesis protein BA204_09600 ENOG4105DSE periplasmic solute binding protein BA204_09605 ENOG4105K4T epimerase BA204_09615 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA204_09660 ENOG4107T5V SNARE associated Golgi BA204_09675 ENOG4108PJD permease BA204_09685 ENOG4108S4H thioesterase Superfamily protein BA204_09690 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA204_09710 ENOG4105SXS Protein of unknown function (DUF456) BA204_09715 ENOG4105C37 (CBS) domain BA204_09735 ENOG4108Z7R Chaperone CsaA BA204_09750 ENOG4108ZRV stage ii sporulation protein p BA204_09760 ENOG4108VXD carboxy-peptidase BA204_09790 ENOG4108ZRV stage ii sporulation protein p BA204_09800 ENOG4108X4Q Hydrolase BA204_09815 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA204_09825 ENOG41087PP glycosyltransferase MGT family BA204_09830 ENOG4108JYZ YitT family BA204_09835 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA204_09865 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BA204_09885 ENOG4106PAW secretion accessory protein EsaA YueB BA204_09895 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BA204_09900 ENOG4108MGT Required for secretion of EsxA and EsxB BA204_09960 ENOG4105KBJ sporulation protein ytfj BA204_09985 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BA204_10005 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BA204_10010 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BA204_10020 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BA204_10025 ENOG4105EMN RNA polymerase sigma factor BA204_10050 ENOG4108V06 Glutathione peroxidase BA204_10065 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA204_10075 ENOG4108IUE nitrate reductase beta subunit BA204_10080 ENOG4105R3A Nitrate reductase BA204_10090 ENOG4107V6Q Cyclic nucleotide-binding domain BA204_10095 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BA204_10100 ENOG4105D06 uba thif-type nad fad binding protein BA204_10105 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA204_10110 ENOG4108ZAF Molybdopterin BA204_10135 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BA204_10140 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BA204_10145 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BA204_10150 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BA204_10155 ENOG4108IFG nitrite reductase, (NAD(P)H) BA204_10160 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BA204_10195 ENOG4105MCT stage V sporulation protein S BA204_10230 ENOG4105C5H ABC transporter BA204_10245 ENOG4108UUM single-stranded DNA-binding protein BA204_10250 ENOG4107A6P BA204_10270 ENOG4107YX5 Pfam:DUF548 BA204_10275 ENOG4105C75 arginyL-tRNA synthetase BA204_10295 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BA204_10310 ENOG4105C5S asparaginyl-tRNA synthetase BA204_10315 ENOG4105C8J )-transporter BA204_10335 ENOG4107XGZ Hydrolase BA204_10340 ENOG4105CY2 Citrate transporter BA204_10360 ENOG4105KD7 acetyltransferase BA204_10370 ENOG4105VMP Transcriptional regulator BA204_10375 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BA204_10400 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BA204_10415 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BA204_10420 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BA204_10430 ENOG4107RVG penicillin-binding protein BA204_10435 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BA204_10440 ENOG4105E9Q Acyl-transferase BA204_10445 ENOG4108UT2 hemolysin iii BA204_10455 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BA204_10465 ENOG4108RCR degv family BA204_10475 ENOG4108KF3 Electron transport protein SCO1 SenC BA204_10480 ENOG4107Y70 Heat shock protein BA204_10485 ENOG4105CAQ asparagine synthetase BA204_10500 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BA204_10505 ENOG4108MES Periplasmic binding protein BA204_10510 ENOG4105F0I Aminotransferase BA204_10535 ENOG4105D8X mechanosensitive ion channel BA204_10540 ENOG4105BZU Histidine kinase BA204_10545 ENOG4105WH1 Two component transcriptional regulator luxr family BA204_10550 ENOG4106KNT transcriptional regulator BA204_10555 ENOG4107ZY0 Phenazine biosynthesis-like protein BA204_10575 ENOG4105CMG Carbohydrate kinase BA204_10615 ENOG4108IJ8 ABC transporter BA204_10620 ENOG4105E90 ABC transporter BA204_10655 ENOG4105C37 (CBS) domain BA204_10680 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA204_10695 ENOG4107S4Y M20 DapE family protein YgeY BA204_10700 ENOG4108TSC N-acetyltransferase BA204_10705 ENOG4108JUB Transcriptional regulator BA204_10710 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BA204_10755 ENOG410841Q phosphoesterase PA-phosphatase related protein BA204_10765 ENOG4105SZ6 Thioredoxin BA204_10795 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA204_10850 ENOG4105BZ4 penicillin-binding protein BA204_10860 ENOG4105CZM Major Facilitator BA204_10865 ENOG4105W8X HesB YadR YfhF-family protein BA204_10875 ENOG4105DXD 2-methylcitrate dehydratase BA204_10880 ENOG4105CR4 methylisocitrate lyase BA204_10885 ENOG4105C1G acyl-Coa dehydrogenase BA204_10890 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA204_10900 ENOG4105N14 lysine exporter protein LysE YggA BA204_10905 ENOG4105E39 Enoyl-CoA hydratase BA204_10920 ENOG4107RFY SbcCD D subunit BA204_10925 ENOG4105EYH Exonuclease BA204_10945 ENOG4105FCD Major Facilitator BA204_10950 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BA204_10955 ENOG4105E4F Isochorismate synthase BA204_10960 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BA204_10965 ENOG4105WQI isochorismatase BA204_10970 ENOG4105CEY Amp-dependent synthetase and ligase BA204_10975 ENOG4105WQT MbtH domain protein BA204_10980 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_10995 ENOG4105K70 DNA-binding protein BA204_11015 ENOG4105BZG amino acid carrier protein BA204_11040 ENOG4105FE9 pseudouridine synthase BA204_11045 ENOG4105C22 threonyL-tRNA synthetase BA204_11050 ENOG4105C19 ABC transporter BA204_11105 ENOG41081I9 integral membrane protein BA204_11115 ENOG4108Y4K DNA-binding transcriptional activator BA204_11130 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BA204_11140 ENOG4105EYF MMPL domain protein BA204_11165 ENOG4105WCN acetyltransferase BA204_11190 ENOG4105C1Q protoporphyrinogen oxidase BA204_11200 ENOG41068WN BA204_11230 ENOG4107V2S Transcriptional regulator BA204_11235 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA204_11250 ENOG4105DND Transcriptional regulator BA204_11255 ENOG4108RPX mosc domain containing protein BA204_11270 ENOG4105BZ1 (ABC) transporter BA204_11275 ENOG4105BZ1 (ABC) transporter BA204_11325 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BA204_11330 ENOG4108KPJ rna polymerase sigma factor BA204_11355 ENOG4105F32 YngK protein BA204_11380 ENOG4105RD7 BadF BadG BcrA BcrD BA204_11385 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BA204_11400 ENOG4108INS Transcriptional regulator BA204_11415 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BA204_11420 ENOG4105C1J atp-dependent rna helicase BA204_11430 ENOG4108RZE Tetr family transcriptional regulator BA204_11485 ENOG4108QY0 Membrane BA204_11520 ENOG41088CC tellurite resistance protein tehB BA204_11535 ENOG4107RA9 decarboxylase BA204_11540 ENOG4105K56 Transcriptional regulator BA204_11545 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BA204_11570 ENOG4105CIN aminoacyl-histidine dipeptidase BA204_11595 ENOG4105KRN Transcriptional regulator, abrb family BA204_11605 ENOG4105EJ9 Membrane BA204_11610 ENOG4105EQK -acetyltransferase BA204_11645 ENOG4105W8Z 4'-phosphopantetheinyl transferase BA204_11720 ENOG4105EJQ L-serine dehydratase BA204_11725 ENOG4105C44 Serine transporter BA204_11745 ENOG4105F6S Spore photoproduct lyase BA204_11755 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BA204_11760 ENOG4105CNI cell division protein FtsW BA204_11765 ENOG4105CJW magnesium transporter BA204_11775 ENOG4107RVG penicillin-binding protein BA204_11790 ENOG4107RF6 penicillin-binding protein BA204_11795 ENOG4107RF6 penicillin-binding protein BA204_11805 ENOG4105DIN metallophosphoesterase BA204_11815 ENOG4105CJ1 ABC, transporter BA204_11825 ENOG4107Z3H Transcriptional regulator, TetR family BA204_11840 ENOG4105C1G acyl-Coa dehydrogenase BA204_11845 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BA204_11850 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BA204_11855 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BA204_11860 ENOG4105E39 Enoyl-CoA hydratase BA204_11865 ENOG4107QX3 carboxylase BA204_11870 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA204_11890 ENOG4105DBI uridine monophosphokinase BA204_11910 ENOG4105DZ1 carboxypeptidase BA204_11935 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BA204_11955 ENOG41075H3 AraC family transcriptional regulator BA204_11985 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BA204_12010 ENOG4107Y80 Major Facilitator superfamily BA204_12060 ENOG4105EFA 4-hydroxyphenylacetate BA204_12080 ENOG410900G Protein of unknown function (DUF421) BA204_12085 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BA204_12095 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BA204_12165 ENOG4105D6E homoserine dehydrogenase BA204_12175 ENOG4105CPF Cell wall formation (By similarity) BA204_12180 ENOG4105ETU transcriptional activator (TenA BA204_12215 ENOG4105VTR Integrase BA204_12255 ENOG4105KRN Transcriptional regulator, abrb family BA204_12425 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BA204_12515 ENOG410667J hydrolase BA204_12520 ENOG4105BZU Histidine kinase BA204_12525 ENOG4107RF6 penicillin-binding protein BA204_12550 ENOG4108JJB ABC transporter BA204_12560 ENOG4108HGU Histidine kinase BA204_12605 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_12610 ENOG4105GR3 Histidine kinase BA204_12615 ENOG4105CB2 alcohol dehydrogenase BA204_12620 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BA204_12625 ENOG4105CJN penicillin-binding protein BA204_12665 ENOG4105F27 Major Facilitator BA204_12670 ENOG4107Y80 Major Facilitator superfamily BA204_12685 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BA204_12710 ENOG4107Y9U Membrane BA204_12730 ENOG4105EGD dinuclear metal center protein, YbgI family BA204_12755 ENOG4105FCD Major Facilitator BA204_12765 ENOG4105E09 nadh pyrophosphatase BA204_12770 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BA204_12795 ENOG4108XI2 Domain of unknown function (DUF1963) BA204_12815 ENOG4108NRW Phospholipase, patatin family BA204_12820 ENOG4105KWG Pfam:DUF1696 BA204_12830 ENOG4108YYS metal-dependent hydrolase (By similarity) BA204_12845 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BA204_12855 ENOG4105PKS Excinuclease abc c subunit domain protein BA204_12890 ENOG4107VFR oxidoreductase BA204_12915 ENOG4105U0R haloacid dehalogenase-like hydrolase BA204_12920 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_12925 ENOG4105BZU Histidine kinase BA204_12945 ENOG4107WD8 ABC transporter, permease BA204_12960 ENOG4105DY8 decarboxylase BA204_12975 ENOG4108IUM Glycogen debranching enzyme BA204_12985 ENOG4105CGH 5'-nucleotidase BA204_13000 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BA204_13005 ENOG4105FDR Membrane BA204_13010 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA204_13060 ENOG4105MSI germination protein ypeb BA204_13090 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BA204_13095 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BA204_13100 ENOG4107Z3H Transcriptional regulator, TetR family BA204_13130 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BA204_13145 ENOG4105E98 transcriptional regulator DeoR family BA204_13160 ENOG41062ES Transcriptional regulator BA204_13180 ENOG4107QKR Dehydrogenase BA204_13190 ENOG4107RUY (E1 component), alpha subunit BA204_13200 ENOG4105E1F short-chain dehydrogenase reductase BA204_13205 ENOG4105RHY Pfam:UPF0157 BA204_13235 ENOG4107SQ8 Glycine betaine BA204_13240 ENOG4108IJ7 Glycine betaine BA204_13265 ENOG4105E66 phosphoriboisomerase A BA204_13270 ENOG41082BV acetyltransferase BA204_13275 ENOG4108M1A Chitin-binding protein BA204_13280 ENOG41087PP glycosyltransferase MGT family BA204_13305 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA204_13310 ENOG4105MSB protein, conserved in bacteria BA204_13335 ENOG4108Z7F N-acetyltransferase BA204_13355 ENOG4105EEM helicase BA204_13370 ENOG4105C9U ATP-dependent DNA helicase RecQ BA204_13410 ENOG4108M1A Chitin-binding protein BA204_13425 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BA204_13435 ENOG4105BZG amino acid carrier protein BA204_13440 ENOG4105C26 Dehydrogenase BA204_13445 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA204_13450 ENOG4105CTU Proline racemase BA204_13460 ENOG41080HI glycine oxidase BA204_13470 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BA204_13515 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BA204_13535 ENOG4105DTQ mandelate racemase muconate lactonizing BA204_13550 ENOG4107SET aldo keto reductase BA204_13585 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BA204_13595 ENOG4105BZU Histidine kinase BA204_13600 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_13625 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BA204_13640 ENOG4105DPN Oligoendopeptidase f BA204_13645 ENOG4105EPR degv family BA204_13705 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BA204_13710 ENOG4106K7D Major facilitator family transporter BA204_13730 ENOG4107BMA Transglycosylase associated protein BA204_13745 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) BA204_13780 ENOG4105CHM Aminotransferase BA204_13795 ENOG4108ZMI UPF0477 protein BA204_13835 ENOG4105C02 permease BA204_13845 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BA204_13850 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BA204_13855 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BA204_13860 ENOG4105D7T ABC transporter BA204_13885 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BA204_13925 ENOG4107VC0 DNA alkylation repair enzyme BA204_13930 ENOG4105C6T cysteine synthase BA204_13935 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BA204_13940 ENOG4107VMI polysaccharide deacetylase BA204_13945 ENOG4108ZCF integral membrane protein BA204_13950 ENOG4105E0M Sulfatase BA204_13955 ENOG4105C5H ABC transporter BA204_13965 ENOG41082JN Transcriptional regulator BA204_13990 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BA204_13995 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BA204_14040 ENOG41069ER domain protein BA204_14050 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BA204_14080 ENOG4105D4B ABC, transporter BA204_14085 ENOG4105F5R ABC transporter BA204_14090 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BA204_14100 ENOG4105DKT Transcriptional regulator BA204_14105 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BA204_14115 ENOG41061GT Aldolase BA204_14120 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BA204_14150 ENOG4105II7 pyrroline-5-carboxylate reductase BA204_14160 ENOG4107258 Transcriptional regulator BA204_14175 ENOG4105ECK Fatty Acid Desaturase BA204_14185 ENOG4107RBI VanW family BA204_14190 ENOG4105G6Z alkaline phosphatase BA204_14200 ENOG4105VMP Transcriptional regulator BA204_14225 ENOG41068WN BA204_14250 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA204_14275 ENOG4105CKK Glycosyl transferase, family 2 BA204_14305 ENOG4105C8Y Acetylornithine aminotransferase BA204_14350 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA204_14385 ENOG4108TVJ Nitroreductase BA204_14390 ENOG4105FS7 Transcriptional regulator BA204_14405 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BA204_14410 ENOG4105WEC Molybdate metabolism regulator BA204_14420 ENOG4105CMR udp-glucose 4-epimerase BA204_14425 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BA204_14450 ENOG4108DMH HTH_ARAC BA204_14455 ENOG4108FWV Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BA204_14460 ENOG4108XET gCN5-related N-acetyltransferase BA204_14475 ENOG4108PCN EamA-like transporter family BA204_14485 ENOG4107XJU UPF0178 protein BA204_14540 ENOG410635A Membrane BA204_14550 ENOG4108IQI permease BA204_14560 ENOG4105F1N DNA alkylation repair BA204_14595 ENOG4107RF6 penicillin-binding protein BA204_14605 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BA204_14625 ENOG4105E7W lamb ycsf family protein BA204_14635 ENOG4105P4J Allophanate hydrolase, subunit 1 BA204_14640 ENOG4107258 Transcriptional regulator BA204_14650 ENOG4106N3A copper homeostasis protein cutc BA204_14655 ENOG4108ZHR arsR family transcriptional regulator BA204_14665 ENOG4105FDT acyl-CoA dehydrogenase BA204_14720 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BA204_14730 ENOG4105CAQ asparagine synthetase BA204_14735 ENOG4105DND Transcriptional regulator BA204_14770 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BA204_14795 ENOG4105E2A Dehydrogenase BA204_14805 ENOG4108IJ0 Aspartate ammonia-lyase BA204_14810 ENOG4105HDK L-asparaginase BA204_14815 ENOG4108IMY Transcriptional regulator BA204_14825 ENOG4108B31 Spore germination protein BA204_14840 ENOG4105BZU Histidine kinase BA204_14845 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_14855 ENOG4105BZU Histidine kinase BA204_14880 ENOG41075H3 AraC family transcriptional regulator BA204_14890 ENOG4105YWU small acid-soluble spore protein BA204_14895 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BA204_14900 ENOG4105CUB amino acid BA204_14905 ENOG4105II7 pyrroline-5-carboxylate reductase BA204_14910 ENOG4108NHD germination protein BA204_14915 ENOG4108Q8B Spore germination protein BA204_14960 ENOG4105CGH 5'-nucleotidase BA204_14970 ENOG4105CHJ isochorismatase hydrolase BA204_14995 ENOG4105EQ0 Major Facilitator superfamily BA204_15040 ENOG4105F6J Alpha beta hydrolase fold BA204_15055 ENOG4108606 TspO/MBR family BA204_15060 ENOG4105CVP deoxyribo-dipyrimidine photolyase BA204_15105 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BA204_15120 ENOG4108TWJ NADH dehydrogenase subunit 5 BA204_15125 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BA204_15130 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_15150 ENOG4107VMI polysaccharide deacetylase BA204_15160 ENOG4105BZU Histidine kinase BA204_15165 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_15190 ENOG4108VJ1 Transcriptional regulator (CarD family BA204_15205 ENOG4105FR1 rard protein BA204_15220 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BA204_15225 ENOG4105ECQ AraC Family Transcriptional Regulator BA204_15230 ENOG4105Z7P Acetyltransferase (GNAT) family BA204_15240 ENOG4105D6J arsenicaL-resistance protein BA204_15245 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BA204_15250 ENOG41085FC arsR family transcriptional regulator BA204_15260 ENOG4105NAE bifunctional deaminase-reductase domain protein BA204_15275 ENOG4107P5I polyketide synthase BA204_15280 ENOG4108IG5 Transcriptional regulator BA204_15330 ENOG4108NIW Leucine export protein LeuE BA204_15370 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BA204_15375 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_15390 ENOG4105K6H D-cysteine desulfhydrase BA204_15400 ENOG4105E0Y RtcB Protein BA204_15410 ENOG4105JQZ Methyltransferase BA204_15430 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BA204_15445 ENOG4105BZU Histidine kinase BA204_15455 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BA204_15485 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BA204_15520 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BA204_15665 ENOG4108VXD carboxy-peptidase BA204_15670 ENOG4105PNM synthesis protein BA204_15680 ENOG4108ISG Major Facilitator BA204_15695 ENOG4107MII Sugar-specific transcriptional regulator TrmB BA204_15700 ENOG4105CZM Major Facilitator BA204_15710 ENOG4105CRW Short chain fatty acid transporter BA204_15780 ENOG4108K8S endonuclease I BA204_15795 ENOG4108Z66 YbaK ebsC protein BA204_15800 ENOG4105CUT histidyl-tRNA synthetase BA204_15815 ENOG4105KVH Transcriptional regulator BA204_15820 ENOG4108RCM Nitroreductase BA204_15850 ENOG4108PSK reductase BA204_15910 ENOG4105C31 Tryptophanyl-tRNA synthetase BA204_15915 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BA204_15950 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BA204_15960 ENOG4105EV4 Multidrug resistance protein mdtH BA204_15990 ENOG4105C37 (CBS) domain BA204_16005 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BA204_16010 ENOG4105FAW cDP-glucose 4,6-dehydratase BA204_16045 ENOG4105DDN Pentapeptide repeat-containing protein BA204_16050 ENOG4105XDF Protein of unknown function (DUF1272) BA204_16055 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BA204_16060 ENOG4105CMG Carbohydrate kinase BA204_16065 ENOG4105C6Z Gluconate BA204_16070 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA204_16080 ENOG4105CV1 Transketolase (EC 2.2.1.1) BA204_16085 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BA204_16105 ENOG4105C8Q Methyl-accepting chemotaxis BA204_16110 ENOG4108UX3 '-nucleotidase BA204_16115 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BA204_16120 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BA204_16125 ENOG4105KVH Transcriptional regulator BA204_16145 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BA204_16150 ENOG4105CHH sulfate transporter BA204_16165 ENOG4105C44 Serine transporter BA204_16190 ENOG4108TZY GntR Family Transcriptional Regulator BA204_16195 ENOG4105D9R oxidoreductase BA204_16235 ENOG4105JAB phenazine biosynthesis protein, phzf family BA204_16245 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BA204_16250 ENOG4105KVH Transcriptional regulator BA204_16260 ENOG4108ZJ4 polysaccharide deacetylase BA204_16330 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BA204_16340 ENOG4107YXZ hydrolase, family 25 BA204_16370 ENOG4105H3G oxidoreductase BA204_16435 ENOG4108TN2 lmbE family BA204_16445 ENOG4107R3E Citrate transporter BA204_16455 ENOG4105WCN acetyltransferase BA204_16460 ENOG4108MES Periplasmic binding protein BA204_16465 ENOG4105EHG Permease protein BA204_16470 ENOG4105DQ5 transport system permease protein BA204_16475 ENOG4105NX3 Membrane BA204_16495 ENOG4107CUJ Protein of unknown function (DUF2690) BA204_16505 ENOG4107V2S Transcriptional regulator BA204_16535 ENOG4105C98 muts2 protein BA204_16545 ENOG4105E5K Alpha-amylase BA204_16550 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BA204_16560 ENOG4108A04 Beta-lactamase BA204_16585 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BA204_16595 ENOG41082BM Transcriptional regulator, arsr family BA204_16600 ENOG4105CIS alcohol dehydrogenase BA204_16625 ENOG4105RHY Pfam:UPF0157 BA204_16635 ENOG4105CQB FAD linked oxidase domain protein BA204_16660 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BA204_16670 ENOG4107TPS domain protein BA204_16675 ENOG4105CEP NADH dehydrogenase BA204_16685 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BA204_16695 ENOG4108IAJ Nad-dependent epimerase dehydratase BA204_16700 ENOG4105FAW cDP-glucose 4,6-dehydratase BA204_17025 ENOG4105GR3 Histidine kinase BA204_17030 ENOG4105BZU Histidine kinase BA204_17040 ENOG41069ER domain protein BA204_17090 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BA204_17110 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BA204_17145 ENOG4105BZU Histidine kinase BA204_17150 ENOG4105C5H ABC transporter BA204_17170 ENOG4105BZU Histidine kinase BA204_17180 ENOG4105KT7 mgtC SapB transporter BA204_17190 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BA204_17195 ENOG41073R8 VanW family BA204_17205 ENOG4108R1P BA204_17220 ENOG4105VEQ Cold shock protein BA204_17240 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BA204_17260 ENOG410904N short-chain dehydrogenase reductase BA204_17270 ENOG4106IQC argininosuccinate lyase BA204_17285 ENOG4108IA2 Sodium pantothenate symporter BA204_17295 ENOG4105C26 Dehydrogenase BA204_17300 ENOG4105CHR reductase BA204_17310 ENOG4105EWU Squalene--hopene cyclase BA204_17320 ENOG4105FR1 rard protein BA204_17325 ENOG410696E Membrane BA204_17340 ENOG4105D1F ATP-binding protein BA204_17350 ENOG4108ZAF Molybdopterin BA204_17355 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA204_17360 ENOG4105D06 uba thif-type nad fad binding protein BA204_17365 ENOG4105TMB Formate nitrite transporter BA204_17375 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BA204_17380 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BA204_17390 ENOG4108JB9 formate dehydrogenase BA204_17395 ENOG4105E1K spore germination protein BA204_17410 ENOG4105CUB amino acid BA204_17465 ENOG4108KGH TRANSCRIPTIONal BA204_17475 ENOG4105EMN RNA polymerase sigma factor BA204_17485 ENOG4105CIG ABC transporter BA204_17495 ENOG4105D9R oxidoreductase BA204_17505 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA204_17510 ENOG4105K4P CoA-binding domain protein BA204_17515 ENOG4105C0H protease BA204_17520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_17530 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BA204_17535 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BA204_17540 ENOG4105W8X HesB YadR YfhF-family protein BA204_17570 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BA204_17575 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA204_17590 ENOG4105BZ1 (ABC) transporter BA204_17595 ENOG4108I0Z Aconitate hydratase BA204_17625 ENOG4105E5W Transporter BA204_17635 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA204_17655 ENOG4107F3J Amp-dependent synthetase and ligase BA204_17660 ENOG4107ZYJ bioY protein BA204_17665 ENOG4105CEY Amp-dependent synthetase and ligase BA204_17670 ENOG4108IMY Transcriptional regulator BA204_17720 ENOG4107AYK membrAne BA204_17730 ENOG4105BZU Histidine kinase BA204_17735 ENOG4105FBA Phospholipase Carboxylesterase BA204_17740 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BA204_17745 ENOG4105CK7 Sodium proline symporter BA204_17755 ENOG4105CBC glutamate synthase BA204_17760 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BA204_17765 ENOG4108VJ1 Transcriptional regulator (CarD family BA204_17770 ENOG4108903 Formimidoylglutamase BA204_17780 ENOG4105CGP Urocanate hydratase BA204_17795 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BA204_17800 ENOG4108Z0Z intracellular protease Pfpi family BA204_17825 ENOG4107QIV Cytochrome c biogenesis protein BA204_17835 ENOG4105CH2 amidohydrolase BA204_17845 ENOG4105CJ1 ABC, transporter BA204_17860 ENOG4107RSM transcriptional regulator BA204_17865 ENOG4105VAW lrga family BA204_17870 ENOG41067MG lrgb family BA204_17910 ENOG4105BZ1 (ABC) transporter BA204_17915 ENOG4105BZ1 (ABC) transporter BA204_17950 ENOG4108HW3 (ABC) transporter BA204_17955 ENOG4105CGH 5'-nucleotidase BA204_17965 ENOG4108SVB resolvase BA204_17985 ENOG4105K7K Transcriptional regulator BA204_17990 ENOG4105C5F glutamine synthetase BA204_17995 ENOG4105KV4 Transcriptional regulator BA204_18000 ENOG4105CXI aluminum resistance protein BA204_18005 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BA204_18010 ENOG4105EN6 Membrane BA204_18020 ENOG4106F1P AAA ATPase, central domain protein BA204_18050 ENOG41069ER domain protein BA204_18055 ENOG4105DM4 PTS System BA204_18060 ENOG4105DE4 1-phosphofructokinase BA204_18065 ENOG4105E98 transcriptional regulator DeoR family BA204_18070 ENOG4107QW4 alcohol dehydrogenase BA204_18075 ENOG4108SJC Membrane BA204_18090 ENOG4105C85 amino acid BA204_18105 ENOG4105TMB Formate nitrite transporter BA204_18110 ENOG4105K70 DNA-binding protein BA204_18120 ENOG4105C59 p-type ATPase BA204_18125 ENOG410681U heavy metal transport detoxification protein BA204_18130 ENOG4105VPX protein, conserved in bacteria BA204_18135 ENOG4105D01 (LipO)protein BA204_18145 ENOG4105NIV Esterase BA204_18150 ENOG4105E0A ABC, transporter BA204_18175 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA204_18180 ENOG4105D03 DNA-3-methyladenine glycosylase II BA204_18210 ENOG4105BZU Histidine kinase BA204_18230 ENOG4105C5E polysaccharide biosynthesis protein BA204_18245 ENOG41067MG lrgb family BA204_18265 ENOG4108S3Y transcriptional regulator BA204_18270 ENOG4105CS2 ec 3.2.1.21 BA204_18285 ENOG4105F0V Cell wall hydrolase BA204_18295 ENOG4105E0M Sulfatase BA204_18300 ENOG410890F Dynamin family BA204_18335 ENOG4105DQU oxidoreductase, subunit beta BA204_18340 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BA204_18345 ENOG4108IGT Dipeptidase BA204_18350 ENOG4105MCT stage V sporulation protein S BA204_18355 ENOG4105D48 metallophosphoesterase BA204_18380 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BA204_18395 ENOG4105XZV Protein of unknown function (DUF3243) BA204_18400 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BA204_18420 ENOG4105UIB (ABC) transporter BA204_18425 ENOG4108JQ9 ABC transporter BA204_18430 ENOG4105DIH basic membrane BA204_18435 ENOG4105FDP GntR family transcriptional regulator BA204_18440 ENOG4105CNU cell division protein FtsK BA204_18450 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BA204_18460 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA204_18470 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA204_18475 ENOG4108S0H Dipicolinic acid synthetase, b subunit BA204_18480 ENOG4105E35 Dipicolinate synthase subunit A BA204_18490 ENOG4105C1V Peptidase, M16 BA204_18510 ENOG4105DTN riboflavin biosynthesis protein ribF BA204_18525 ENOG4105W7A Protein of unknown function (DUF503) BA204_18535 ENOG4105VHM ribosomal protein BA204_18540 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BA204_18545 ENOG4105CHV Transcription elongation factor NusA BA204_18555 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BA204_18565 ENOG4105DZP Membrane-associated zinc metalloprotease BA204_18570 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BA204_18575 ENOG4105KNE Phosphatidate cytidylyltransferase BA204_18580 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BA204_18590 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BA204_18620 ENOG4108HE4 integrase family BA204_18630 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BA204_18635 ENOG4105C79 DNA protecting protein DprA BA204_18640 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BA204_18655 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BA204_18680 ENOG4105VB6 UPF0109 protein BA204_18700 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BA204_18705 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BA204_18720 ENOG4105CHR reductase BA204_18725 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BA204_18740 ENOG4105CB5 ATP-dependent DNA helicase recG BA204_18745 ENOG4105DP4 dak2 domain fusion protein ylov BA204_18750 ENOG4108ZAA Alkaline-shock protein BA204_18765 ENOG4105FJ0 thiamine BA204_18770 ENOG4105DJV ribulose-phosphate 3-epimerase BA204_18775 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BA204_18780 ENOG4105D9P serine threonine protein kinase BA204_18785 ENOG4108ZF3 Phosphatase BA204_18795 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BA204_18810 ENOG4105C25 Primosomal protein n' BA204_18815 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BA204_18835 ENOG4105DSJ YicC domain protein BA204_18845 ENOG4105F23 Fibronectin-binding protein BA204_18850 ENOG4105DC7 peptidase M24 BA204_18870 ENOG4107XGZ Hydrolase BA204_18890 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BA204_18905 ENOG4105CD3 dihydroorotase BA204_18925 ENOG4105C34 Pseudouridine synthase BA204_18940 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BA204_18950 ENOG4105DBK s4 domain protein BA204_18955 ENOG41067XK integral membrane protein BA204_18965 ENOG4105DFA alanine racemase domain protein BA204_18970 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BA204_18975 ENOG4105WR5 sporulation protein, YlmC YmxH family BA204_18985 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_18995 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BA204_19000 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BA204_19010 ENOG4105D4A Cell wall formation (By similarity) BA204_19015 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BA204_19020 ENOG4105CNI cell division protein FtsW BA204_19035 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BA204_19040 ENOG4105CJN penicillin-binding protein BA204_19045 ENOG4105CJN penicillin-binding protein BA204_19060 ENOG41074B2 UPF0747 protein BA204_19085 ENOG4105KNH Nucleic acid-binding protein BA204_19095 ENOG41063PX domain protein BA204_19100 ENOG4105D78 K07001 NTE family protein BA204_19105 ENOG4105H20 Sporulation integral membrane protein YlbJ BA204_19115 ENOG4106H78 methyltransferase BA204_19135 ENOG4107TB6 phosphoglycerate mutase BA204_19150 ENOG4106UY4 Inherit from COG: Scp-like extracellular BA204_19200 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BA204_19205 ENOG4105CNI cell division protein FtsW BA204_19220 ENOG4108IAB Phoh family BA204_19240 ENOG4105QA2 BA204_19245 ENOG4105CI3 gtp-binding protein typa BA204_19255 ENOG4105ECY inositol monophosphatase BA204_19275 ENOG4105CXN decarboxylase BA204_19325 ENOG4105CPP Dehydrogenase, E1 component BA204_19340 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BA204_19345 ENOG4108X4Q Hydrolase BA204_19355 ENOG4105CN5 Metallo-Beta-Lactamase BA204_19360 ENOG4107ZYR domain protein BA204_19395 ENOG4108XRC Protein of unknown function (DUF458) BA204_19405 ENOG4107IN1 Protein of unknown function (DUF1797) BA204_19420 ENOG4105EPM Diguanylate phosphodiesterase BA204_19425 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BA204_19440 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BA204_19450 ENOG4105UIN BA204_19485 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BA204_19505 ENOG4108HGU Histidine kinase BA204_19515 ENOG4105CHM Aminotransferase BA204_19520 ENOG4105FKQ transcriptional regulator BA204_19525 ENOG4105EG2 ABC transporter, permease BA204_19535 ENOG4107FKK extracellular solute-binding protein family 1 BA204_19545 ENOG4105CG3 alpha amylase, catalytic region BA204_19590 ENOG4105CHU acetyl-coa acetyltransferase BA204_19620 ENOG4105K7K Transcriptional regulator BA204_19625 ENOG4105DTD Dehydrogenase BA204_19645 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BA204_19670 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BA204_19685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA204_19695 ENOG4105BZU Histidine kinase BA204_19715 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA204_19730 ENOG4105CID antiterminator BA204_19740 ENOG4105FDP GntR family transcriptional regulator BA204_19750 ENOG4105CE4 GlcNAc 6-P deacetylase BA204_19785 ENOG4107ZE5 PPIases accelerate the folding of proteins BA204_19790 ENOG4105PTM secreted protein BA204_19795 ENOG4105J7I hydrolase BA204_19805 ENOG4105G6R Stage v sporulation protein ae BA204_19815 ENOG4105CZ3 stage V sporulation protein ad BA204_19820 ENOG41090VF Stage v sporulation protein ac BA204_19840 ENOG4105C8J )-transporter BA204_19845 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_19855 ENOG41082AN stage II sporulation protein BA204_19860 ENOG4105DZ1 carboxypeptidase BA204_19865 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BA204_19870 ENOG4105DVE abc transporter atp-binding protein BA204_19900 ENOG4105D7N magnesium and cobalt transport protein CorA BA204_19925 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA204_19935 ENOG4105I3K Ferric uptake regulator, Fur family BA204_19940 ENOG4105MZ9 stage II sporulation protein m BA204_19960 ENOG4105CPC Aldo Keto reductase BA204_19970 ENOG4105RHY Pfam:UPF0157 BA204_19990 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BA204_20000 ENOG4105ETE Transcriptional regulator (LacI family BA204_20005 ENOG4108YM7 Gcn5-related n-acetyltransferase BA204_20025 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BA204_20030 ENOG4108R6K riboflavin synthase, subunit alpha BA204_20055 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA204_20060 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA204_20075 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA204_20085 ENOG4105DFD Na H antiporter BA204_20090 ENOG4105CGH 5'-nucleotidase BA204_20115 ENOG4105DBV ornithine carbamoyltransferase BA204_20130 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BA204_20145 ENOG4108IXY short-chain dehydrogenase reductase BA204_20150 ENOG41069FQ Metallo-beta-lactamase superfamily BA204_20155 ENOG4105II7 pyrroline-5-carboxylate reductase BA204_20160 ENOG4105EJQ L-serine dehydratase BA204_20170 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BA204_20185 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BA204_20195 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BA204_20200 ENOG4105D9U N-acetyltransferase BA204_20210 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BA204_20215 ENOG4108QEG Membrane BA204_20220 ENOG4105CDA abc transporter atp-binding protein BA204_20225 ENOG4105E5Q amino acid AbC transporter BA204_20230 ENOG4108HW3 (ABC) transporter BA204_20240 ENOG4105G7B Protein of unknown function (DUF2992) BA204_20250 ENOG4108QY0 Membrane BA204_20260 ENOG4105C7S Dehydrogenase BA204_20265 ENOG4105CPP Dehydrogenase, E1 component BA204_20285 ENOG4107RDP Dehydrogenase BA204_20295 ENOG4108JUB Transcriptional regulator BA204_20305 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BA204_20320 ENOG4107QQR Sporulation BA204_20325 ENOG4105S1Z Stage IV sporulation protein B BA204_20330 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BA204_20335 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BA204_20340 ENOG4105DX0 Hemolysin A BA204_20350 ENOG4105CTB Polyprenyl synthetase BA204_20365 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BA204_20375 ENOG4108ZSR alkaline shock protein BA204_20380 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BA204_20400 ENOG410644B Stage III sporulation protein af BA204_20410 ENOG4105KQ4 Stage iii sporulation protein ad BA204_20415 ENOG4108CQH stage III sporulation protein AC BA204_20420 ENOG4105KR5 Stage iii sporulation protein BA204_20425 ENOG4105CD2 stage iii sporulation protein aa BA204_20450 ENOG4105DC7 peptidase M24 BA204_20455 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BA204_20465 ENOG4105CBJ Metal-dependent enzyme BA204_20475 ENOG4107YBY Hydrolase BA204_20500 ENOG41082GG biotin lipoate A B protein ligase BA204_20505 ENOG4105WZW rhodanese family BA204_20530 ENOG41080TC multidrug resistance protein BA204_20570 ENOG4105C0D helicase BA204_20690 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BA204_20695 ENOG4105C3R Methionine synthase BA204_20705 ENOG4105C28 cystathionine BA204_20710 ENOG4105C28 cystathionine BA204_20730 ENOG4105C5X domain protein BA204_20740 ENOG4105DKQ ROK family BA204_20750 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BA204_20765 ENOG4108UTW Plays a role in the regulation of phosphate uptake BA204_20770 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BA204_20775 ENOG4105C8U phosphate abc transporter BA204_20780 ENOG4105C8U phosphate abc transporter BA204_20790 ENOG4107RF6 penicillin-binding protein BA204_20800 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA204_20825 ENOG4105N80 Ferric uptake regulator, Fur family BA204_20835 ENOG4105FDK ABC transporter BA204_20840 ENOG4108JYZ YitT family BA204_20845 ENOG41069ZM Protein of unknown function (DUF2624) BA204_20870 ENOG4105EGD dinuclear metal center protein, YbgI family BA204_20885 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_20890 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BA204_20915 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BA204_20920 ENOG4105KG3 cytidine deaminase BA204_20925 ENOG4107YR5 Diacylglycerol kinase BA204_20935 ENOG4105CTJ Metal Dependent Phosphohydrolase BA204_20940 ENOG4105C9A Phoh family BA204_20950 ENOG41068P3 sporulation protein YqfC BA204_20955 ENOG4105KTH gatB Yqey BA204_20965 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BA204_20970 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BA204_21000 ENOG4105CSA Coproporphyrinogen iii oxidase BA204_21005 ENOG4105KVH Transcriptional regulator BA204_21030 ENOG4105TQK DNA polymerase iii, delta' subunit BA204_21040 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BA204_21045 ENOG4108UK2 deaminase BA204_21050 ENOG4105KQC Competence protein BA204_21060 ENOG4105DXX methyltransferase BA204_21070 ENOG4108WF2 Metal Dependent Phosphohydrolase BA204_21080 ENOG410812S Rna-binding protein BA204_21090 ENOG4105CQW ribosome biogenesis GTPase YqeH BA204_21095 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BA204_21110 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_21130 ENOG4108TVJ Nitroreductase BA204_21145 ENOG4105G6Z alkaline phosphatase BA204_21150 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BA204_21155 ENOG4108MUZ hydrolase BA204_21195 ENOG4105MIR Phenylalanine 4-monooxygenase BA204_21205 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BA204_21245 ENOG4105S6R Iron-hydroxamate transporter permease subunit BA204_21250 ENOG4108V5C ABC transporter BA204_21260 ENOG4108EKI Dehydrogenase BA204_21265 ENOG4105C28 cystathionine BA204_21295 ENOG4107XRG penicillin-binding protein BA204_21305 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BA204_21315 ENOG4105CFP Peptidase U32 BA204_21320 ENOG4105XYU peptidase (U32 family) BA204_21325 ENOG4108VQJ O-methyltransferase BA204_21330 ENOG4105HHA aminodeoxychorismate lyase BA204_21350 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA204_21360 ENOG4105C02 permease BA204_21375 ENOG41060CR BA204_21380 ENOG4105C7H Helicase, RecD TraA family BA204_21390 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BA204_21395 ENOG4105C3J Cysteine desulfurase BA204_21405 ENOG4105D1H recombination factor protein RarA BA204_21410 ENOG4108VCI transcription factor, rsfa family BA204_21415 ENOG4105CUZ uba thif-type nad fad binding protein BA204_21425 ENOG4105CUT histidyl-tRNA synthetase BA204_21435 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BA204_21440 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BA204_21450 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BA204_21455 ENOG41076HS cation diffusion facilitator family transporter BA204_21460 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BA204_21470 ENOG4105CKP Polysaccharide Biosynthesis Protein BA204_21475 ENOG4108QG2 Membrane BA204_21485 ENOG4105VIE preprotein translocase, subunit YajC BA204_21500 ENOG41061AI Protein of unknown function (DUF2905) BA204_21515 ENOG4108HUF Transporter BA204_21545 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BA204_21550 ENOG4108IYU L-aspartate oxidase BA204_21565 ENOG4108RPX mosc domain containing protein BA204_21575 ENOG4105CQC Prephenate dehydratase BA204_21590 ENOG4105C19 ABC transporter BA204_21595 ENOG4105EWM Histidine kinase BA204_21605 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BA204_21620 ENOG4105X36 (ribosomal) protein BA204_21645 ENOG4107QMS site-determining protein BA204_21660 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BA204_21665 ENOG4105DFF Rod shape-determining protein mreb BA204_21685 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BA204_21690 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BA204_21700 ENOG41068KH stage VI sporulation protein D BA204_21710 ENOG4105D52 delta-aminolevulinic acid dehydratase BA204_21735 ENOG4105K56 Transcriptional regulator BA204_21755 ENOG4108IUQ atp-dependent protease BA204_21780 ENOG4108QCI YvbH-like oligomerisation region BA204_21800 ENOG4105M59 Phosphodiesterase, mj0936 family BA204_21805 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BA204_21815 ENOG4108XJQ germination protein BA204_21830 ENOG4105PFC Transcriptional regulator BA204_21840 ENOG4105DZC cytosine deaminase BA204_21845 ENOG41067S9 phage shock protein C, PspC BA204_21850 ENOG4108JCI Transcriptional regulator BA204_21860 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BA204_21865 ENOG4108Z40 Transcriptional regulator BA204_21870 ENOG4105RHA ABC transporter, permease BA204_21875 ENOG4108IUX (ABC) transporter BA204_21880 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BA204_21890 ENOG4105E14 MotA TolQ exbB proton channel BA204_21895 ENOG4108VXD carboxy-peptidase BA204_21905 ENOG4105E33 succinate dehydrogenase BA204_21915 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BA204_21925 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BA204_21930 ENOG4105K63 Thioredoxin BA204_21935 ENOG4105C10 Electron transfer flavoprotein BA204_21940 ENOG4105BZJ Electron transfer flavoprotein BA204_21945 ENOG41060WC Enoyl-CoA hydratase BA204_21950 ENOG4107Z3H Transcriptional regulator, TetR family BA204_21955 ENOG4105CEY Amp-dependent synthetase and ligase BA204_21965 ENOG4105J76 Periplasmic binding protein BA204_21970 ENOG4105S6R Iron-hydroxamate transporter permease subunit BA204_22015 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_22030 ENOG4105DR4 Methyltransferase BA204_22040 ENOG4105KFN sortase, SrtB family BA204_22045 ENOG4105E0A ABC, transporter BA204_22060 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BA204_22070 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BA204_22080 ENOG4105FE9 pseudouridine synthase BA204_22090 ENOG4105DCG PHP domain protein BA204_22105 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BA204_22125 ENOG4105C5S asparaginyl-tRNA synthetase BA204_22130 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BA204_22140 ENOG4108RWN rrna methyltransferase BA204_22170 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA204_22175 ENOG4105CW7 secretion protein, HlyD family BA204_22180 ENOG4108JGH Tetr family transcriptional regulator BA204_22185 ENOG4105CN9 Peptidase m42 family protein BA204_22205 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BA204_22210 ENOG4105C22 threonyL-tRNA synthetase BA204_22215 ENOG4108TDW sporulation protein YtxC BA204_22240 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BA204_22245 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BA204_22250 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BA204_22260 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BA204_22265 ENOG4105C2M dna polymerase I BA204_22270 ENOG4105BZU Histidine kinase BA204_22275 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_22290 ENOG4108HMX isocitrate dehydrogenase (NADP) BA204_22295 ENOG4105BZN citrate synthase BA204_22305 ENOG4108REF Sporulation integral membrane protein ytvi BA204_22310 ENOG4105FS0 cytoplasmic membrane protein BA204_22335 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BA204_22340 ENOG4105C6K Malic enzyme BA204_22345 ENOG4105C0B DNA polymerase III (alpha subunit) BA204_22350 ENOG4105VV2 BA204_22360 ENOG4105SFS phosphoesterase RecJ domain protein BA204_22390 ENOG4105DC7 peptidase M24 BA204_22420 ENOG4105Z7P Acetyltransferase (GNAT) family BA204_22425 ENOG41082W1 Cupin 2, conserved barrel domain protein BA204_22445 ENOG4107YZX Universal stress protein BA204_22480 ENOG4108JYZ YitT family BA204_22500 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BA204_22510 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BA204_22515 ENOG4105KBJ sporulation protein ytfj BA204_22530 ENOG4105EFZ amidohydrolase BA204_22540 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA204_22565 ENOG4105RQF LysR family Transcriptional regulator BA204_22575 ENOG4105U5Y Transcriptional regulator BA204_22585 ENOG4105C28 cystathionine BA204_22610 ENOG4108IBT Inherit from COG: transposase BA204_22620 ENOG4108IBT Inherit from COG: transposase BA204_22650 ENOG4105EMN RNA polymerase sigma factor BA204_22660 ENOG4108UW5 maltose o-acetyltransferase BA204_22670 ENOG4105F1V Acetoin utilization protein BA204_22675 ENOG4105W87 Cbs domain BA204_22680 ENOG4105DGU Histone deacetylase BA204_22695 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA204_22700 ENOG4105BZU Histidine kinase BA204_22705 ENOG4107SNB ankyrin repeat protein YahD BA204_22710 ENOG4105EP9 oxidoreductase BA204_22730 ENOG4105ETE Transcriptional regulator (LacI family BA204_22735 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BA204_22755 ENOG4105C88 aminopeptidase BA204_22800 ENOG4108VDD TRNA binding domain protein BA204_22830 ENOG4105C8F Beta-lactamase domain protein BA204_22845 ENOG4108V15 phosphotransferase enzyme family BA204_22850 ENOG4108IUM Glycogen debranching enzyme BA204_22860 ENOG4107QSE Dipeptidase BA204_22865 ENOG4105YW5 deoR family transcriptional regulator BA204_22880 ENOG4105CBX hi0933 family BA204_22915 ENOG4108VJ1 Transcriptional regulator (CarD family BA204_22920 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BA204_22925 ENOG4105CSC Glucose uptake protein BA204_22940 ENOG4108ZAF Molybdopterin BA204_22945 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BA204_22950 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA204_22960 ENOG4105D06 uba thif-type nad fad binding protein BA204_22965 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BA204_22985 ENOG41085GJ domain protein BA204_22995 ENOG4105DWV Homoserine O-trans-acetylase BA204_23005 ENOG4108B31 Spore germination protein BA204_23035 ENOG4105C8T Leucyl-tRNA synthetase BA204_23040 ENOG410605W Major Facilitator BA204_23045 ENOG4107S91 Sodium hydrogen exchanger BA204_23050 ENOG4105NCW Trka-c domain protein BA204_23065 ENOG4105C19 ABC transporter BA204_23085 ENOG4105N5T Radical SAM Protein BA204_23095 ENOG4105DA5 (ABC) transporter BA204_23115 ENOG4107A6P BA204_23145 ENOG4105E8V Alpha Beta Hydrolase Fold protein BA204_23150 ENOG4108Z0R Transferase BA204_23155 ENOG4105YVM Phosphoesterase, PA-phosphatase related BA204_23160 ENOG4105BZF Glycosyl transferase (Group 1 BA204_23170 ENOG4105EPU Molybdenum cofactor synthesis domain protein BA204_23185 ENOG4108MK9 spermidine N(1)-acetyltransferase BA204_23225 ENOG4105BZU Histidine kinase BA204_23230 ENOG4105BZU Histidine kinase BA204_23235 ENOG4107S9D Alpha beta hydrolase BA204_23240 ENOG4107T7U Sulfatase BA204_23255 ENOG4105D2X ABC transporter substrate-binding protein BA204_23265 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BA204_23280 ENOG4107XGZ Hydrolase BA204_23330 ENOG4108V2W Carbonate dehydratase BA204_23335 ENOG4105C4M (Ubiquinol oxidase) subunit I BA204_23340 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA204_23375 ENOG41087YS Phage shock protein A BA204_23400 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BA204_23405 ENOG4105BZU Histidine kinase BA204_23410 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_23435 ENOG4108UGV hypoxanthine phosphoribosyltransferase BA204_23440 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BA204_23480 ENOG4107ZTW SNARE associated Golgi BA204_23495 ENOG4105C19 ABC transporter BA204_23500 ENOG41086D8 Transcriptional regulator BA204_23510 ENOG4105CJ1 ABC, transporter BA204_23520 ENOG41082BM Transcriptional regulator, arsr family BA204_23560 ENOG4105C6Z Gluconate BA204_23565 ENOG4105FDP GntR family transcriptional regulator BA204_23585 ENOG41069H0 dihydroorotase EC 3.5.2.3 BA204_23605 ENOG4105DTQ mandelate racemase muconate lactonizing BA204_23615 ENOG4108IPT Naphthoate synthase BA204_23620 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BA204_23630 ENOG4105E4F Isochorismate synthase BA204_23635 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BA204_23645 ENOG4105VEQ Cold shock protein BA204_23680 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BA204_23695 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BA204_23790 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BA204_23825 ENOG4105KT7 mgtC SapB transporter BA204_23830 ENOG4107PBV potassium channel BA204_23845 ENOG4105WG9 Conserved Protein BA204_23855 ENOG4105CHM Aminotransferase BA204_23860 ENOG4108ZB6 transcriptional regulator AsnC family BA204_23865 ENOG4105C5I Dehydrogenase BA204_23870 ENOG4108MUZ hydrolase BA204_23880 ENOG4105C87 Aminotransferase class I and II BA204_23895 ENOG4105Y38 Kinase-associated protein B BA204_23905 ENOG4107R3E Citrate transporter BA204_23920 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BA204_23925 ENOG4105KA0 thioesterase Superfamily protein BA204_23940 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA204_23965 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BA204_23970 ENOG4106YN8 Prenyltransferase BA204_23985 ENOG41069ER domain protein BA204_24000 ENOG4105CEP NADH dehydrogenase BA204_24030 ENOG4105EWC Purine nucleoside phosphorylase BA204_24040 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BA204_24060 ENOG4108JJA ABC, transporter BA204_24065 ENOG4105C4B ABC transporter, permease BA204_24070 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BA204_24125 ENOG41083MR nifu domain-containing protein BA204_24140 ENOG4108W5N phosphatidylglycerophosphatase a BA204_24160 ENOG4105DAX Pfam:DUF2983 BA204_24170 ENOG4105DYS nad(p)h dehydrogenase (quinone) BA204_24175 ENOG4105D4U had-superfamily hydrolase, subfamily iia BA204_24190 ENOG4105CBT Fructose-1,6-bisphosphatase BA204_24205 ENOG4105MMD transcriptional regulator BA204_24210 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BA204_24215 ENOG4107TXC Transcriptional regulator BA204_24220 ENOG41090T1 Membrane BA204_24245 ENOG4105FAA peptidase M23 BA204_24250 ENOG4108YTE sporulation protein YunB BA204_24255 ENOG4105KZD Domain of unknown function (DUF1805) BA204_24260 ENOG4107R8B 5'-nucleotidase BA204_24265 ENOG4105DIW FeS assembly protein SUFB BA204_24270 ENOG4108UNV SUF system FeS assembly protein, NifU family BA204_24275 ENOG4105C9B Cysteine desulfurase BA204_24280 ENOG4105JRK feS assembly protein SufD BA204_24285 ENOG4105C3K feS assembly ATPase SufC BA204_24290 ENOG4105D01 (LipO)protein BA204_24295 ENOG4108UMI ABC transporter, permease BA204_24300 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BA204_24325 ENOG41080E8 Transcriptional regulator, Spx MgsR family BA204_24345 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BA204_24365 ENOG4108W8B Beta-lactamase domain protein BA204_24370 ENOG4105C1G acyl-Coa dehydrogenase BA204_24375 ENOG4105CHU acetyl-coa acetyltransferase BA204_24390 ENOG4105DZ1 carboxypeptidase BA204_24410 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BA204_24425 ENOG4108SUT Major Facilitator Superfamily BA204_24430 ENOG4107R7I amino acid BA204_24445 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BA204_24455 ENOG4107AYK membrAne BA204_24490 ENOG4107ZTW SNARE associated Golgi BA204_24500 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA204_24505 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_24510 ENOG4105BZU Histidine kinase BA204_24525 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BA204_24540 ENOG4105C8Q Methyl-accepting chemotaxis BA204_24545 ENOG4105VG1 fes assembly suf system protein BA204_24550 ENOG4105D4Y metalloprotease BA204_24570 ENOG4107S91 Sodium hydrogen exchanger BA204_24575 ENOG4105NCW Trka-c domain protein BA204_24585 ENOG4108RMU ferritin dps family protein BA204_24605 ENOG4108URH decarboxylase BA204_24615 ENOG41090A1 ferritin BA204_24620 ENOG4105DHF Membrane BA204_24625 ENOG4105D9N nucleoside BA204_24630 ENOG4105D9N nucleoside BA204_24645 ENOG4108RYK Nad-dependent epimerase dehydratase BA204_24660 ENOG4105CV8 reductase BA204_24665 ENOG4105F27 Major Facilitator BA204_24670 ENOG4105KVH Transcriptional regulator BA204_24685 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BA204_24690 ENOG4105D4A Cell wall formation (By similarity) BA204_24700 ENOG4105C8Q Methyl-accepting chemotaxis BA204_24710 ENOG4105WMR Protein CrcB homolog BA204_24715 ENOG4105WMR Protein CrcB homolog BA204_24735 ENOG4105C5H ABC transporter BA204_24740 ENOG4108MK9 spermidine N(1)-acetyltransferase BA204_24745 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BA204_24770 ENOG4108IPW abc transporter atp-binding protein BA204_24775 ENOG4105CM4 permease protein BA204_24790 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_24810 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BA204_24820 ENOG4105XZU Preprotein translocase, subunit SecG BA204_24825 ENOG41067MG lrgb family BA204_24875 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_24895 ENOG41090VF Stage v sporulation protein ac BA204_24900 ENOG4105CZ3 stage V sporulation protein ad BA204_24915 ENOG4108QY0 Membrane BA204_24920 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BA204_24930 ENOG4105KRI phosphocarrier protein (HPr BA204_24940 ENOG4105CHW UPF0052 protein BA204_24945 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BA204_24950 ENOG4108Z4K mutator MutT protein BA204_24960 ENOG4105C3M thioredoxin reductase BA204_24970 ENOG4108S4C acetyltransferase BA204_24990 ENOG41086DT Membrane protein of unknown function BA204_25000 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BA204_25005 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BA204_25020 ENOG4107TXC Transcriptional regulator BA204_25040 ENOG4105DUM transcriptional regulator, lysR family BA204_25050 ENOG4108WS4 fmn reductase BA204_25065 ENOG4105BZ1 (ABC) transporter BA204_25075 ENOG4105CN1 protease BA204_25080 ENOG4105CRP Part of the ABC transporter FtsEX involved in BA204_25085 ENOG4105CAK Cell division ATP-binding protein ftsE BA204_25095 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BA204_25110 ENOG4108RDQ ABC transporter BA204_25140 ENOG4105MS2 ribosomal subunit Interface protein BA204_25145 ENOG4105VEQ Cold shock protein BA204_25150 ENOG41081UC Inherit from COG: Competence protein BA204_25165 ENOG4105KVH Transcriptional regulator BA204_25175 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BA204_25180 ENOG4108KGH TRANSCRIPTIONal BA204_25185 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BA204_25190 ENOG4105C6Y Udp-glucose 6-dehydrogenase BA204_25195 ENOG4105ESV Glycosyl transferase, family 4 BA204_25205 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA204_25225 ENOG4105F8D glycoside hydrolase family 4 BA204_25230 ENOG4105VCP PTS System BA204_25235 ENOG4105CK1 PTS System BA204_25245 ENOG4105VCP PTS System BA204_25255 ENOG4105VZJ PTS System BA204_25275 ENOG4105ECB domain protein BA204_25280 ENOG4107RSM transcriptional regulator BA204_25315 ENOG4105DAA L-lactate BA204_25325 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BA204_25335 ENOG4105E0M Sulfatase BA204_25360 ENOG4107R8N Glycosyl transferase, family 2 BA204_25370 ENOG4105C94 Transporter BA204_25375 ENOG41069ER domain protein BA204_25400 ENOG4105KBK Zinc finger, swim domain protein BA204_25405 ENOG4105C0D helicase BA204_25435 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA204_25445 ENOG4107RBB ABC transporter, permease BA204_25450 ENOG4105C19 ABC transporter BA204_25460 ENOG4105CXY transporter BA204_25475 ENOG4105BZU Histidine kinase BA204_25480 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_25490 ENOG4108KGH TRANSCRIPTIONal BA204_25495 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BA204_25505 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BA204_25510 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BA204_25520 ENOG4105CPK Glycosyl transferase (Group 1 BA204_25525 ENOG4107EF8 Glycosyl transferase (Group 1 BA204_25560 ENOG4107U9V N5-(Carboxyethyl)ornithine synthase BA204_25570 ENOG4108PTS heparinase ii BA204_25580 ENOG4105D3Q Sugar transferase BA204_25585 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA204_25590 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BA204_25595 ENOG4107YJ4 chain length determinant protein BA204_25600 ENOG4105HTX biosynthesis protein BA204_25605 ENOG4107YJ4 chain length determinant protein BA204_25620 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BA204_25630 ENOG4105FRN stage II sporulation protein BA204_25645 ENOG4105DY9 regulatoR BA204_25665 ENOG4106778 Protein of unknown function (DUF1146) BA204_25670 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA204_25675 ENOG4105C8S subunit m BA204_25680 ENOG4105D65 subunit l BA204_25705 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA204_25710 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BA204_25720 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BA204_25725 ENOG4105BZU Histidine kinase BA204_25775 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BA204_25780 ENOG41062M3 atp synthase BA204_25800 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BA204_25805 ENOG4108UIC UPF0340 protein BA204_25810 ENOG4108YZG isomerase BA204_25825 ENOG4108VGI doxx family BA204_25830 ENOG4107XC4 flavin reductase domain protein, FMN-binding BA204_25845 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BA204_25855 ENOG4108ZXQ stage ii sporulation protein r BA204_25860 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BA204_25865 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BA204_25870 ENOG4107104 thymidine kinase BA204_25880 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BA204_25890 ENOG4105CBT Fructose-1,6-bisphosphatase BA204_25895 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BA204_25915 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BA204_25930 ENOG4105C1G acyl-Coa dehydrogenase BA204_25935 ENOG4105C1G acyl-Coa dehydrogenase BA204_25940 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA204_25950 ENOG4105DF6 Fe-S oxidoreductase BA204_25965 ENOG4105BZU Histidine kinase BA204_25980 ENOG4105D4Y metalloprotease BA204_25990 ENOG4105BZU Histidine kinase BA204_25995 ENOG4105KCT ABC transporter BA204_26000 ENOG4108M15 ABC transporter BA204_26005 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BA204_26015 ENOG4105IIU Aminopeptidase BA204_26035 ENOG4105EMN RNA polymerase sigma factor BA204_26045 ENOG410684U Domain of unknown function (DUF1934) BA204_26065 ENOG4105CYW agmatinase BA204_26075 ENOG4105DXB Major Facilitator superfamily BA204_26080 ENOG4107SWG transcriptional regulator MERR family BA204_26085 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BA204_26090 ENOG4105BZ4 penicillin-binding protein BA204_26095 ENOG4108XFG YwhD family BA204_26100 ENOG4108Z4T Peptidase M50 BA204_26105 ENOG41069HH 4-oxalocrotonate tautomerase BA204_26110 ENOG4105DCI Phosphohydrolase BA204_26115 ENOG4108MES Periplasmic binding protein BA204_26120 ENOG4105E0A ABC, transporter BA204_26125 ENOG4105EHG Permease protein BA204_26130 ENOG4105DQ5 transport system permease protein BA204_26140 ENOG4108VCI transcription factor, rsfa family BA204_26145 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BA204_26150 ENOG4108IJ2 phosphate acetyltransferase BA204_26155 ENOG4107UEZ chlorite dismutase BA204_26165 ENOG4108VKI Cell wall hydrolase BA204_26185 ENOG4107SVH Potassium channel protein BA204_26195 ENOG410667J hydrolase BA204_26200 ENOG4105VCH membrane BA204_26210 ENOG4108TU7 Inherit from COG: (ABC) transporter BA204_26215 ENOG4105CJ1 ABC, transporter BA204_26220 ENOG41090WU lipolytic protein G-D-S-L family BA204_26235 ENOG4105D6E homoserine dehydrogenase BA204_26260 ENOG4108Y4K DNA-binding transcriptional activator BA204_26270 ENOG4105WH1 Two component transcriptional regulator luxr family BA204_26275 ENOG4105BZU Histidine kinase BA204_26280 ENOG4105DWF phosphomethylpyrimidine kinase BA204_26285 ENOG4105BZU Histidine kinase BA204_26290 ENOG4105VCD cytoplasmic protein BA204_26295 ENOG4105D22 carbon starvation protein BA204_26300 ENOG4105DY9 regulatoR BA204_26305 ENOG41079KZ Major Facilitator Superfamily BA204_26315 ENOG4105CG5 Glycosyl transferase (Group 1 BA204_26325 ENOG4105EN6 Membrane BA204_26330 ENOG4106YBV Methyl-accepting chemotaxis BA204_26340 ENOG4108S4H thioesterase Superfamily protein BA204_26350 ENOG4105K64 Glycosyl transferase, family 2 BA204_26365 ENOG4105CKK Glycosyl transferase, family 2 BA204_26370 ENOG4105C5H ABC transporter BA204_26375 ENOG41067SE Tetr family transcriptional regulator BA204_26385 ENOG4105E0X reductase BA204_26390 ENOG4106F5Q Membrane BA204_26405 ENOG4108NEV two component transcriptional regulator, LytTR family BA204_26410 ENOG4108HRK Histidine kinase BA204_26415 ENOG4107RGD Major Facilitator superfamily BA204_26430 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA204_26440 ENOG4105IW1 AmiS UreI transporter BA204_26445 ENOG4105CMR udp-glucose 4-epimerase BA204_26450 ENOG4108UT2 hemolysin iii BA204_26460 ENOG4105C1J atp-dependent rna helicase BA204_26465 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BA204_26480 ENOG4105BZU Histidine kinase BA204_26495 ENOG4105C0H protease BA204_26500 ENOG4105Q2H domain protein BA204_26515 ENOG4105BZU Histidine kinase BA204_26520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA204_26545 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BA204_26550 ENOG4105CDU Replicative dna helicase BA204_26560 ENOG4105BZR domain protein BA204_26575 ENOG4108UUM single-stranded DNA-binding protein BA204_26585 ENOG4105C3G gtp-binding protein BA204_26590 ENOG4105VDK protein, conserved in bacteria BA204_26595 ENOG4105D8X mechanosensitive ion channel BA204_26600 ENOG4108ZDA Sporulation protein YyaC BA204_26605 ENOG4105FA0 parb-like partition protein BA204_26610 ENOG4107QJE Chromosome Partitioning Protein BA204_26625 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BA204_26630 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BA204_26640 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BA204_26665 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA204_26680 ENOG4105C19 ABC transporter BA204_26800 ENOG4105CTC Lipopolysaccharide biosynthesis protein-like protein BA204_26805 ENOG4105CJ1 ABC, transporter BA204_26810 ENOG4108KYE ABC-2 type transporter BA204_26820 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BA204_26825 ENOG4105CHR reductase BA204_26835 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BA204_26850 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BA204_26855 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA204_26860 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BA204_26865 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BA204_26875 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BA204_26880 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BA204_26900 ENOG41067FT ParB-like nuclease domain BA204_26915 ENOG4105DBV ornithine carbamoyltransferase BA204_26945 ENOG4105IBP Cyclic peptide transporter BA204_26950 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BA204_26955 ENOG4105C0W non-ribosomal peptide synthetase BA204_26970 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BA204_26975 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA204_26990 ENOG4105C1G acyl-Coa dehydrogenase BA204_27010 ENOG4105C0W non-ribosomal peptide synthetase BA204_27010 ENOG4105C0W non-ribosomal peptide synthetase BA204_27040 ENOG4107SET aldo keto reductase BA204_27055 ENOG4105NA0 Transcriptional regulator BA204_27065 ENOG4107VMI polysaccharide deacetylase BA204_27075 ENOG4108IMY Transcriptional regulator BA204_27090 ENOG4108M1A Chitin-binding protein BA204_27100 ENOG4105E1K spore germination protein BA204_27165 ENOG4105DG6 mannose-6-phosphate isomerase BA204_27170 ENOG4105DM4 PTS System BA204_27195 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA204_27210 ENOG4108QY0 Membrane BA204_27310 ENOG4107D63 BA204_27315 ENOG4105VZ8 Transcriptional regulator BA204_27320 ENOG4105VXR cytoplasmic protein BA204_27380 ENOG4105KRN Transcriptional regulator, abrb family BA204_27385 ENOG4107A6P BA204_27585 ENOG4108EKI Dehydrogenase BA204_27590 ENOG4105D7V transposase BA204_27605 ENOG4107R7I amino acid BA204_27615 ENOG4105C7B Threonine dehydratase BA204_27620 ENOG4105CUB amino acid BA204_27660 ENOG4105EA8 2-Nitropropane dioxygenase BA204_27670 ENOG4107WD8 ABC transporter, permease BA204_27690 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C BA204_27705 ENOG4105CZV ABC transporter BA204_27720 ENOG4108NNZ chitinase BA204_27730 ENOG4108JUA Transcriptional regulator BA204_27735 ENOG4105CMT Dihydroxyacetone kinase BA204_27745 ENOG4105KRI phosphocarrier protein (HPr BA204_27750 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BA204_27760 ENOG4105ETZ PTS System BA204_27765 ENOG4105F3R pts system mannose fructose sorbose family iid BA204_27775 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BA204_27780 ENOG41067TZ transcriptional regulator, MarR family BA204_27850 ENOG4107QJE Chromosome Partitioning Protein BA204_27865 ENOG41067QW Transcriptional regulator BA204_27910 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BA204_27920 ENOG4108IBT Inherit from COG: transposase BA204_27930 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BA204_27935 ENOG4105XSJ toxin secretion phage lysis holin BA204_28035 ENOG4108C33 Resolvase BA204_28065 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BA204_28120 ENOG4105CFF transcriptional regulator