locus-tag class description BA202_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BA202_00015 ENOG410848D S4 domain protein YaaA BA202_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA202_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BA202_00100 ENOG4105ZMH deoxynucleoside kinase BA202_00110 ENOG4105GTG Isochorismatase BA202_00120 ENOG4108Z6B deaminase BA202_00130 ENOG4105C6E dna polymerase iii BA202_00150 ENOG41067KS pro-sigma K processing BA202_00185 ENOG4105CXN decarboxylase BA202_00195 ENOG4105FA2 dna polymerase iii BA202_00200 ENOG4105MA4 psp1 domain protein BA202_00210 ENOG41060K3 Methyltransferase BA202_00220 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BA202_00225 ENOG4105KRN Transcriptional regulator, abrb family BA202_00235 ENOG4105F8V Hydrolase, tatD family BA202_00240 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BA202_00250 ENOG4105XFA sporulation peptidase YabG BA202_00255 ENOG4105W42 Veg protein BA202_00270 ENOG4105DFT pur operon repressor BA202_00275 ENOG4105KME endoribonuclease L-psp BA202_00290 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BA202_00305 ENOG4108JA2 transcriptioN-repair coupling factor BA202_00310 ENOG4108M14 stage v sporulation protein t BA202_00320 ENOG4108IY2 MazG family BA202_00325 ENOG41082I2 s4 domain protein BA202_00330 ENOG4105VYY sporulation protein yabp BA202_00345 ENOG41060GV RNA binding s1 domain protein BA202_00370 ENOG4108UGV hypoxanthine phosphoribosyltransferase BA202_00375 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BA202_00390 ENOG4105C6T cysteine synthase BA202_00395 ENOG4105CRQ synthase (Component I) BA202_00400 ENOG4105DDQ anthranilate synthase BA202_00405 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BA202_00410 ENOG4105EEI dihydropteroate synthase BA202_00415 ENOG4105KRF dihydroneopterin aldolase BA202_00420 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BA202_00430 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BA202_00520 ENOG4108Z0C Uvrb UvrC protein BA202_00535 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BA202_00545 ENOG4105CTP PilT protein domain protein BA202_00565 ENOG4105D7W serine acetyltransferase BA202_00580 ENOG4105C2N RNA methyltransferase TrmH family group 3 BA202_00585 ENOG4105M0M Tetracycline resistance protein BA202_00590 ENOG4105QIV RNA polymerase BA202_00605 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BA202_00630 ENOG4107Y49 methyltransferase BA202_00645 ENOG4105XPM ribosomal protein BA202_00750 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BA202_00775 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BA202_00785 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BA202_00795 ENOG41067V7 50S ribosomal protein L36 BA202_00830 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BA202_00860 ENOG4105D1F ATP-binding protein BA202_00875 ENOG4108NMV polysaccharide deacetylase BA202_00955 ENOG4105C8B TIGR00159 family BA202_00960 ENOG4107U5W ybbr family BA202_01005 ENOG4108PSK reductase BA202_01010 ENOG4108UMI ABC transporter, permease BA202_01020 ENOG4105D01 (LipO)protein BA202_01025 ENOG4105EE1 crotonyl-CoA reductase BA202_01035 ENOG4105IQ5 FAD linked oxidase domain protein BA202_01050 ENOG4105C2C drug resistance transporter, Bcr CflA BA202_01065 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA202_01070 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA202_01075 ENOG4105C3U ABC transporter BA202_01080 ENOG4108JQ7 (ABC) transporter BA202_01100 ENOG4105MKU Transcriptional regulator BA202_01110 ENOG4108J59 Extracellular solute-binding protein, family 5 BA202_01115 ENOG4108J59 Extracellular solute-binding protein, family 5 BA202_01135 ENOG4107XDY Nicotinamide Mononucleotide Transporter BA202_01145 ENOG4105E0C molybdate abc transporter BA202_01150 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BA202_01155 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BA202_01190 ENOG4105F6E Acyl-transferase BA202_01215 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BA202_01230 ENOG4108RE7 deoxyribonuclease BA202_01240 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BA202_01265 ENOG4105C5H ABC transporter BA202_01275 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BA202_01280 ENOG4105DEF Extracellular solute-binding protein, family 5 BA202_01290 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA202_01295 ENOG4105C3U ABC transporter BA202_01300 ENOG4108JQ7 (ABC) transporter BA202_01305 ENOG410667J hydrolase BA202_01335 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BA202_01340 ENOG4105ERH Fumarylacetoacetate hydrolase BA202_01350 ENOG4105CUB amino acid BA202_01355 ENOG4108SC4 )-transporter BA202_01360 ENOG4105CPF Cell wall formation (By similarity) BA202_01365 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BA202_01390 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BA202_01395 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA202_01405 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BA202_01505 ENOG4105K8N protein family UPF0079, ATPase BA202_01510 ENOG41072GX Peptidase M22 Glycoprotease BA202_01515 ENOG410801F ribosomal-protein-alanine acetyltransferase BA202_01525 ENOG4105C5H ABC transporter BA202_01540 ENOG4108TYN CAAX amino terminal protease family protein BA202_01585 ENOG4105C7N Xanthine uracil vitamin C permease BA202_01595 ENOG4105BZU Histidine kinase BA202_01620 ENOG4107ZXU DSBA oxidoreductase BA202_01650 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA202_01670 ENOG4108SHN Glycosyl transferase, family 2 BA202_01710 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA202_01735 ENOG4105SX7 Transporter BA202_01760 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BA202_01765 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BA202_01770 ENOG4105C83 adenylosuccinate lyase BA202_01780 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BA202_01805 ENOG4108V3E phosphoribosylglycinamide formyltransferase BA202_01815 ENOG4105C12 Phosphoribosylglycinamide synthetase BA202_01845 ENOG4105C4R Atp-dependent dna helicase BA202_01875 ENOG4108W2Y isochorismatase BA202_01885 ENOG4108UMI ABC transporter, permease BA202_01890 ENOG4105D01 (LipO)protein BA202_01910 ENOG410834F Transcriptional regulator BA202_01915 ENOG4107I77 yiaA/B two helix domain BA202_01935 ENOG4105CBD Diacylglycerol kinase BA202_01940 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BA202_01945 ENOG4108JPW Aminotransferase BA202_01955 ENOG4105C26 Dehydrogenase BA202_01960 ENOG4105KPY Small multidrug resistance protein BA202_01975 ENOG4105D9N nucleoside BA202_01980 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BA202_01995 ENOG4105BZU Histidine kinase BA202_02000 ENOG4108W15 Protein of unknown function (DUF1456) BA202_02025 ENOG4105DTQ mandelate racemase muconate lactonizing BA202_02035 ENOG4105DFD Na H antiporter BA202_02060 ENOG4105D3R alkyl hydroperoxide reductase BA202_02075 ENOG4107W7X Aldolase BA202_02090 ENOG4105EHG Permease protein BA202_02095 ENOG4105DQ5 transport system permease protein BA202_02100 ENOG4108V5C ABC transporter BA202_02125 ENOG4106UIA BA202_02130 ENOG4106UIA BA202_02160 ENOG410756H nucleotidyltransferase BA202_02165 ENOG4105D2S major facilitator superfamily BA202_02190 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BA202_02195 ENOG4105E5Q amino acid AbC transporter BA202_02200 ENOG4105EAB amino acid AbC transporter BA202_02210 ENOG4105C8Q Methyl-accepting chemotaxis BA202_02215 ENOG4105C8Q Methyl-accepting chemotaxis BA202_02220 ENOG4105DNP FAD linked oxidase domain protein BA202_02230 ENOG4105CI1 PTS System BA202_02260 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BA202_02275 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component BA202_02295 ENOG4105C5H ABC transporter BA202_02310 ENOG4105D7V transposase BA202_02330 ENOG41062JF Transcriptional regulator BA202_02350 ENOG4105DEU major facilitator superfamily BA202_02380 ENOG4108N0M stress protein BA202_02385 ENOG4106FN3 tellurium resistance protein BA202_02390 ENOG4106FN3 tellurium resistance protein BA202_02395 ENOG4107TS3 membrane protein, TerC BA202_02400 ENOG4108TTB tellurium resistance protein BA202_02420 ENOG4105KJF protein tyrosine phosphatase BA202_02430 ENOG4107U9T Pfam:Ribonuclease_BN BA202_02435 ENOG4105C59 p-type ATPase BA202_02440 ENOG4108IPJ Membrane BA202_02455 ENOG4105C3F Signal peptidase i BA202_02465 ENOG4107ZTW SNARE associated Golgi BA202_02480 ENOG410606W general stress protein BA202_02485 ENOG4105UPD Calcium Proton BA202_02535 ENOG4108JUB Transcriptional regulator BA202_02545 ENOG4108IQI permease BA202_02575 ENOG4105DQ6 Transposase BA202_02590 ENOG4105CSV Glutaminase BA202_02600 ENOG4108A04 Beta-lactamase BA202_02615 ENOG4105CKK Glycosyl transferase, family 2 BA202_02620 ENOG4107QQG Dehydrogenase BA202_02625 ENOG4105C3I Nad-dependent epimerase dehydratase BA202_02645 ENOG4105F1A Pyruvate formate-lyase BA202_02665 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BA202_02670 ENOG4105ECP epimerase BA202_02700 ENOG41067AE Membrane-bound metal-dependent hydrolase BA202_02705 ENOG4105CEN a g-specific adenine glycosylase BA202_02710 ENOG4106BXE BA202_02730 ENOG4105BZ1 (ABC) transporter BA202_02735 ENOG4107NBY Membrane BA202_02740 ENOG4105CBC glutamate synthase BA202_02750 ENOG4108IUW ABC transporter BA202_02770 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA202_02775 ENOG4105G5W regulator Fur family BA202_02890 ENOG4108JQC penicillin-binding protein 1A BA202_02895 ENOG4107ZQN disulfide bond BA202_02905 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BA202_02915 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BA202_02920 ENOG4105BZU Histidine kinase BA202_02930 ENOG4105CYN Serine protein kinase BA202_02955 ENOG4105CT1 (ABC) transporter BA202_02960 ENOG4105CDA abc transporter atp-binding protein BA202_02965 ENOG4105DRP amino acid AbC transporter BA202_02970 ENOG4105DRP amino acid AbC transporter BA202_02975 ENOG4105C94 Transporter BA202_02990 ENOG4105DZ6 Band 7 protein BA202_03000 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BA202_03005 ENOG4108V9W transcriptional regulatory protein BA202_03010 ENOG4105D4T Citrate transporter BA202_03035 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BA202_03040 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA202_03045 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BA202_03050 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BA202_03055 ENOG4105BZ7 extracellular solute-binding protein family 1 BA202_03060 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BA202_03065 ENOG4108STX response regulator BA202_03070 ENOG4105US7 Histidine kinase BA202_03095 ENOG4108UZ3 Transporter BA202_03100 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA202_03110 ENOG4105BZU Histidine kinase BA202_03115 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_03125 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BA202_03130 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BA202_03135 ENOG4108JB9 formate dehydrogenase BA202_03155 ENOG4105CUB amino acid BA202_03165 ENOG4105C59 p-type ATPase BA202_03170 ENOG4105DAP Nicotinate phosphoribosyltransferase BA202_03200 ENOG41073R8 VanW family BA202_03205 ENOG4108KGH TRANSCRIPTIONal BA202_03210 ENOG4105D9N nucleoside BA202_03215 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BA202_03220 ENOG4105C37 (CBS) domain BA202_03225 ENOG4108IJ0 Aspartate ammonia-lyase BA202_03235 ENOG4105DAA L-lactate BA202_03250 ENOG4105DUX Transporter BA202_03255 ENOG4108MES Periplasmic binding protein BA202_03260 ENOG4105DQ5 transport system permease protein BA202_03265 ENOG4108IHU transport system permease protein BA202_03270 ENOG4105E0A ABC, transporter BA202_03275 ENOG4105DMQ Methyltransferase BA202_03285 ENOG4105EXW epimerase dehydratase BA202_03290 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BA202_03305 ENOG4107T89 von Willebrand factor, type A BA202_03310 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BA202_03315 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA202_03330 ENOG4105BZU Histidine kinase BA202_03335 ENOG4105D5Q Arginine ornithine antiporter BA202_03340 ENOG4107414 GntR family transcriptional regulator BA202_03345 ENOG4105C5Y PTS System BA202_03350 ENOG4105CG3 alpha amylase, catalytic region BA202_03365 ENOG4105E1K spore germination protein BA202_03370 ENOG4105CRN Aminoglycoside phosphotransferase BA202_03375 ENOG4105BZG amino acid carrier protein BA202_03380 ENOG4105CDA abc transporter atp-binding protein BA202_03385 ENOG4105CT1 (ABC) transporter BA202_03390 ENOG4105EAD ABC transporter BA202_03395 ENOG4105DRP amino acid AbC transporter BA202_03400 ENOG4108IQI permease BA202_03425 ENOG4105D29 Helix-turn-helix type 11 domain protein BA202_03430 ENOG4105NAE bifunctional deaminase-reductase domain protein BA202_03435 ENOG4105BZU Histidine kinase BA202_03450 ENOG4105CHH sulfate transporter BA202_03455 ENOG41068KF Universal stress protein BA202_03465 ENOG4105DEF Extracellular solute-binding protein, family 5 BA202_03475 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA202_03480 ENOG4108JQ7 (ABC) transporter BA202_03490 ENOG4105CXY transporter BA202_03495 ENOG41067TZ transcriptional regulator, MarR family BA202_03500 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_03505 ENOG4105ETE Transcriptional regulator (LacI family BA202_03510 ENOG4108RVA ribokinase BA202_03525 ENOG4105CNN ABC, transporter BA202_03530 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BA202_03535 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA202_03600 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BA202_03605 ENOG41069ER domain protein BA202_03610 ENOG4105VZ8 Transcriptional regulator BA202_03615 ENOG4107D63 BA202_03630 ENOG4105DUX Transporter BA202_03650 ENOG4105C85 amino acid BA202_03655 ENOG4105C7N Xanthine uracil vitamin C permease BA202_03670 ENOG4105MA6 gCN5-related N-acetyltransferase BA202_03695 ENOG4105BZ9 Cytochrome C oxidase, subunit I BA202_03700 ENOG4105E2S oxidase) subunit II BA202_03720 ENOG4106CAD Protein of unknown function (DUF3311) BA202_03725 ENOG4105E1V na solute symporter BA202_03740 ENOG4108NHD germination protein BA202_03750 ENOG4105CE1 Ferrous iron transport protein b BA202_03755 ENOG4105CE1 Ferrous iron transport protein b BA202_03760 ENOG4105CE1 Ferrous iron transport protein b BA202_03765 ENOG4105CVA phosphate BA202_03770 ENOG4105C8U phosphate abc transporter BA202_03775 ENOG4105E2Z phosphate ABC transporter (Permease BA202_03910 ENOG41080XQ Signal transduction protein with cbs domains BA202_03935 ENOG4105ETU transcriptional activator (TenA BA202_03945 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BA202_03955 ENOG4108VEU Thiamine monophosphate synthase BA202_03960 ENOG41080HI glycine oxidase BA202_03975 ENOG4105D06 uba thif-type nad fad binding protein BA202_03980 ENOG4105DWF phosphomethylpyrimidine kinase BA202_04030 ENOG4108INS Transcriptional regulator BA202_04045 ENOG4105C7N Xanthine uracil vitamin C permease BA202_04055 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA202_04090 ENOG4108B31 Spore germination protein BA202_04110 ENOG4107Y03 Nitroreductase BA202_04115 ENOG4105ED1 spovr family BA202_04130 ENOG4108TCS Glutamyl endopeptidase BA202_04155 ENOG4105XTG Pfam:DUF156 BA202_04160 ENOG4105VFE sira family BA202_04165 ENOG4107TPS domain protein BA202_04170 ENOG4105VFE sira family BA202_04175 ENOG41085GJ domain protein BA202_04180 ENOG4105VFE sira family BA202_04185 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BA202_04190 ENOG41087NI Sulfite exporter TauE/SafE BA202_04200 ENOG4108KGH TRANSCRIPTIONal BA202_04225 ENOG4105EMD TRANSCRIPTIONal BA202_04230 ENOG4105VCP PTS System BA202_04235 ENOG4105VZJ PTS System BA202_04255 ENOG41069ER domain protein BA202_04260 ENOG4107RBB ABC transporter, permease BA202_04265 ENOG4105C19 ABC transporter BA202_04300 ENOG4105WEF catalase BA202_04335 ENOG4107T5V SNARE associated Golgi BA202_04370 ENOG4105CUB amino acid BA202_04375 ENOG4107RWR Sodium hydrogen exchanger BA202_04385 ENOG4106KNT transcriptional regulator BA202_04430 ENOG4108YXU transcriptional regulator AsnC family BA202_04440 ENOG4105DQ6 Transposase BA202_04450 ENOG4105KPY Small multidrug resistance protein BA202_04455 ENOG4105KPY Small multidrug resistance protein BA202_04470 ENOG4105DQ6 Transposase BA202_04490 ENOG4105NF4 modulator of drug activity BA202_04495 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BA202_04500 ENOG4105E5W Transporter BA202_04510 ENOG4107RKG DJ-1/PfpI family BA202_04520 ENOG4105D5Q Arginine ornithine antiporter BA202_04525 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BA202_04530 ENOG4105C26 Dehydrogenase BA202_04540 ENOG4105BZ1 (ABC) transporter BA202_04545 ENOG4105BZ1 (ABC) transporter BA202_04555 ENOG4105DRP amino acid AbC transporter BA202_04560 ENOG4105CDA abc transporter atp-binding protein BA202_04575 ENOG410839P BA202_04610 ENOG4107FQX Alpha-acetolactate decarboxylase BA202_04625 ENOG4105D4P Coproporphyrinogen iii oxidase BA202_04645 ENOG4105CHH sulfate transporter BA202_04680 ENOG4105IEH endo-beta-N-acetylglucosaminidase BA202_04685 ENOG4105T09 s-layer domain-containing protein BA202_04695 ENOG4105CGU Enoyl-CoA hydratase BA202_04715 ENOG4105DER m42 family BA202_04760 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA202_04770 ENOG4108JQ7 (ABC) transporter BA202_04810 ENOG4105CSH Transporter BA202_04820 ENOG4108MRH transcriptional regulatory protein BA202_04845 ENOG4105C4R Atp-dependent dna helicase BA202_04865 ENOG4107UNZ domain protein BA202_04890 ENOG4105CDU Replicative dna helicase BA202_04970 ENOG4105CID antiterminator BA202_04975 ENOG4105C5Y PTS System BA202_04980 ENOG4105CS2 ec 3.2.1.21 BA202_04990 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BA202_05015 ENOG4105CMT Dihydroxyacetone kinase BA202_05025 ENOG4105CMT Dihydroxyacetone kinase BA202_05035 ENOG410780I phosphoprotein phosphatase activity BA202_05065 ENOG4105FBW Monooxygenase BA202_05180 ENOG4105WN5 stage II sporulation protein BA202_05190 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_05200 ENOG4108MJI response regulator BA202_05205 ENOG4105BZU Histidine kinase BA202_05210 ENOG4105BZU Histidine kinase BA202_05235 ENOG4105K8R UPF0145 protein BA202_05275 ENOG4107VRP DNA repair exonuclease BA202_05280 ENOG4106D4I domain protein BA202_05285 ENOG4105D7V transposase BA202_05320 ENOG4107JM4 Tetratricopeptide repeat BA202_05330 ENOG4108MUZ hydrolase BA202_05340 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BA202_05355 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BA202_05365 ENOG4105EMN RNA polymerase sigma factor BA202_05390 ENOG4105C57 major facilitator superfamily BA202_05395 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_05410 ENOG4105EEM helicase BA202_05415 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA202_05445 ENOG4105K59 histidine triad (HIT) protein BA202_05475 ENOG410905X membrane-flanked domain protein BA202_05480 ENOG4105CKV Membrane BA202_05510 ENOG410905X membrane-flanked domain protein BA202_05515 ENOG4105CKV Membrane BA202_05520 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BA202_05525 ENOG4105BZ4 penicillin-binding protein BA202_05535 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BA202_05565 ENOG4105NA0 Transcriptional regulator BA202_05590 ENOG4105ECB domain protein BA202_05590 ENOG4105ECB domain protein BA202_05620 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BA202_05630 ENOG4105D29 Helix-turn-helix type 11 domain protein BA202_05640 ENOG4106AXD BA202_05645 ENOG4108RQ5 Beta-lactamase domain-containing protein BA202_05650 ENOG4105DF9 Lipoate-protein, ligase BA202_05660 ENOG4105CEY Amp-dependent synthetase and ligase BA202_05675 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BA202_05680 ENOG4108I5D sulfate abc transporter BA202_05685 ENOG4105ECW sulfate abc transporter BA202_05810 ENOG4105ENX hydrolase BA202_05820 ENOG4107TVP HD domain protein BA202_05830 ENOG4108AEY RNA polymerase sigma factor BA202_05835 ENOG41086D8 Transcriptional regulator BA202_05845 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA202_05870 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BA202_05890 ENOG4107QP3 malate synthase g BA202_05905 ENOG4105VEQ Cold shock protein BA202_05920 ENOG4105XVF Competence transcription factor BA202_05990 ENOG4105ERH Fumarylacetoacetate hydrolase BA202_06015 ENOG4105CAQ asparagine synthetase BA202_06025 ENOG4105CH6 catalase BA202_06065 ENOG4105BZU Histidine kinase BA202_06090 ENOG4105QNR S1 RNA binding domain protein BA202_06095 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA202_06105 ENOG4107AYK membrAne BA202_06110 ENOG41073B9 BA202_06120 ENOG4108KP7 hydrolase BA202_06165 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BA202_06170 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BA202_06185 ENOG4105C31 Tryptophanyl-tRNA synthetase BA202_06200 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BA202_06205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BA202_06215 ENOG4108JQ7 (ABC) transporter BA202_06235 ENOG4105UQX Mate efflux family protein BA202_06260 ENOG4108ZCF integral membrane protein BA202_06270 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA202_06280 ENOG4105DPN Oligoendopeptidase f BA202_06295 ENOG4108Z18 K06886 hemoglobin BA202_06300 ENOG4105MIX Adenylate cyclase BA202_06305 ENOG4106EFP UPF0738 protein BA202_06320 ENOG4105EMS pseudouridine synthase BA202_06340 ENOG4105K64 Glycosyl transferase, family 2 BA202_06360 ENOG4107TVC Glycosyl transferase, family 2 BA202_06380 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BA202_06385 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BA202_06395 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BA202_06470 ENOG4105CK7 Sodium proline symporter BA202_06480 ENOG4105CRQ synthase (Component I) BA202_06485 ENOG4105DDQ anthranilate synthase BA202_06565 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BA202_06585 ENOG4105C7S Dehydrogenase BA202_06595 ENOG4105VZ8 Transcriptional regulator BA202_06640 ENOG4105DZ1 carboxypeptidase BA202_06645 ENOG4105VFR signal peptidase BA202_06680 ENOG4105C26 Dehydrogenase BA202_06690 ENOG4105F38 ABC transporter, permease BA202_06695 ENOG4105D38 putrescine abc transporter BA202_06700 ENOG4107RUE extracellular solute-binding protein family 1 BA202_06710 ENOG4105EYF MMPL domain protein BA202_06720 ENOG4108YBP pseudouridine synthase BA202_06730 ENOG4105K4I Scp-like extracellular BA202_06735 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BA202_06740 ENOG4105CQB FAD linked oxidase domain protein BA202_06755 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_06760 ENOG4105BZU Histidine kinase BA202_06765 ENOG4105JXH GntR family transcriptional regulator BA202_06785 ENOG4106A3R peptidase BA202_06795 ENOG4108QTI )-transporter BA202_06800 ENOG4107TS3 membrane protein, TerC BA202_06805 ENOG4105CZN Potassium uptake protein BA202_06810 ENOG410681C small acid-soluble spore protein BA202_06815 ENOG4108Z7G MaoC domain protein dehydratase BA202_06835 ENOG4105CHR reductase BA202_06865 ENOG4105C4Y ABC transporter BA202_06870 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA202_06875 ENOG4107RCV ABC transporter, permease BA202_06895 ENOG4105E98 transcriptional regulator DeoR family BA202_06910 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BA202_06920 ENOG4105PXI polysaccharide deacetylase BA202_06930 ENOG4105BZU Histidine kinase BA202_06935 ENOG41090MY MarR family Transcriptional regulator BA202_06945 ENOG4106DF1 BA202_06955 ENOG4105BZU Histidine kinase BA202_06965 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BA202_06970 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BA202_07020 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BA202_07050 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BA202_07055 ENOG4105CZV ABC transporter BA202_07065 ENOG4105CJ1 ABC, transporter BA202_07100 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BA202_07105 ENOG4105EA8 2-Nitropropane dioxygenase BA202_07110 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BA202_07120 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BA202_07145 ENOG4105NQC Flavodoxin BA202_07215 ENOG4105CZN Potassium uptake protein BA202_07220 ENOG41063Y9 BA202_07225 ENOG4105KBJ sporulation protein ytfj BA202_07255 ENOG4105CM2 brancheD-chain amino acid aminotransferase BA202_07260 ENOG4105C7K acetolactate synthase BA202_07265 ENOG4108ZP8 Acetolactate synthase small subunit BA202_07340 ENOG4107RVV histidinol phosphate phosphatase, hisj family BA202_07355 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BA202_07360 ENOG4105E0M Sulfatase BA202_07370 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BA202_07390 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BA202_07395 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BA202_07405 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BA202_07410 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BA202_07415 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BA202_07425 ENOG4105C8J )-transporter BA202_07445 ENOG4105DFD Na H antiporter BA202_07465 ENOG4105ENE Histidine kinase BA202_07470 ENOG4105WH1 Two component transcriptional regulator luxr family BA202_07490 ENOG41089UC methyltransferase, type 11 BA202_07535 ENOG4105CJ3 phosphate transporter BA202_07540 ENOG4107GRR phosphate transport regulator BA202_07545 ENOG4105BZ4 penicillin-binding protein BA202_07560 ENOG4105BZU Histidine kinase BA202_07565 ENOG4105I3N Conserved Protein BA202_07580 ENOG4105BZU Histidine kinase BA202_07615 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA202_07620 ENOG4105DZ1 carboxypeptidase BA202_07625 ENOG4108JIC nucleoside recognition domain protein BA202_07635 ENOG4105FE9 pseudouridine synthase BA202_07645 ENOG4107TWT Cytochrome c biogenesis protein BA202_07650 ENOG4105CRE cytochrome C BA202_07655 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_07660 ENOG4105BZU Histidine kinase BA202_07665 ENOG4108WBT adenosyltransferase BA202_07670 ENOG41063SB peptidase BA202_07680 ENOG4108SAX Membrane BA202_07695 ENOG4105C9U ATP-dependent DNA helicase RecQ BA202_07700 ENOG4105I7S Abortive infection protein BA202_07710 ENOG4107RGJ metallophosphoesterase BA202_07715 ENOG4107X2D transcriptional regulator, merr family BA202_07720 ENOG4108S6Z Negative regulator of genetic competence BA202_07745 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BA202_07750 ENOG4107RB3 L-asparaginase BA202_07785 ENOG4105S2F BA202_07790 ENOG41065D1 BA202_07820 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BA202_07835 ENOG4105XXQ heptaprenyl diphosphate synthase component I BA202_07845 ENOG4105EAH synthase BA202_07870 ENOG41068YB TPR repeat-containing protein BA202_07885 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BA202_07890 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BA202_07925 ENOG4108JYZ YitT family BA202_07930 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BA202_07945 ENOG4105FJR Lmbe family BA202_07950 ENOG4105CPK Glycosyl transferase (Group 1 BA202_07990 ENOG4105DVT helicase BA202_07995 ENOG4105YAC BA202_08015 ENOG4105CSM endonuclease III BA202_08025 ENOG4105BZ4 penicillin-binding protein BA202_08080 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BA202_08090 ENOG4105DVT helicase BA202_08095 ENOG4105CTD carboxy-peptidase BA202_08105 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BA202_08115 ENOG4105C2W permease BA202_08120 ENOG4105DHF Membrane BA202_08125 ENOG410890F Dynamin family BA202_08135 ENOG4108W0I acetyltransferase BA202_08145 ENOG4105KHC sulfurtransferase BA202_08170 ENOG4106032 Glutathionylspermidine synthase BA202_08200 ENOG4108SZE gCN5-related N-acetyltransferase BA202_08220 ENOG41081VK Ribonuclease BA202_08285 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA202_08295 ENOG4107RWR Sodium hydrogen exchanger BA202_08300 ENOG4105CN5 Metallo-Beta-Lactamase BA202_08305 ENOG4108Z5V transcriptional regulator, merr family BA202_08315 ENOG4105H67 Protein of unknown function (DUF421) BA202_08320 ENOG41080C8 DUF218 domain BA202_08385 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BA202_08395 ENOG4107R0U MotA TolQ exbB proton channel BA202_08400 ENOG4105ER2 Ompa motb domain protein BA202_08405 ENOG4107YTP response regulator receiver protein BA202_08410 ENOG4105CBS Chea signal transduction histidine kinase BA202_08415 ENOG4105DD5 Flagellar motor switch protein BA202_08430 ENOG4105BZU Histidine kinase BA202_08450 ENOG4105E1Q flagellar hook-associated protein BA202_08455 ENOG4105DTJ flagellar hook-associated protein BA202_08460 ENOG410804A Flagellar hook-associated 2 domain-containing protein BA202_08475 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BA202_08480 ENOG4108ZC9 flagellar basal-body rod protein flgc BA202_08485 ENOG41075Z6 flagellar hook-basal body complex protein fliE BA202_08490 ENOG4107U2N Flagellar M-ring protein BA202_08495 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA202_08525 ENOG4105BZE flagellar hook protein, FlgE BA202_08540 ENOG4107R88 Chemotaxis protein (CheV) BA202_08555 ENOG4106WTF Glycosyl transferase, family 2 BA202_08560 ENOG4105K64 Glycosyl transferase, family 2 BA202_08570 ENOG4105I03 Flagellin BA202_08575 ENOG4105E4C Lytic transglycosylase catalytic BA202_08585 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BA202_08590 ENOG4105DD5 Flagellar motor switch protein BA202_08600 ENOG4105CN7 Flagellar biosynthetic protein FliP BA202_08605 ENOG4105VS8 Flagellar biosynthetic protein fliq BA202_08615 ENOG4105D00 flagellar biosynthetic protein flhB BA202_08625 ENOG4105FZW flagellar biosynthesis regulator FlhF BA202_08630 ENOG4105KTQ flagellar basal-body rod protein BA202_08635 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA202_08660 ENOG4108RZE Tetr family transcriptional regulator BA202_08680 ENOG4105KAC Antibiotic biosynthesis monooxygenase BA202_08700 ENOG4108U4N (sortase) family BA202_08725 ENOG4105DUM transcriptional regulator, lysR family BA202_08730 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BA202_08740 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BA202_08745 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BA202_08760 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BA202_08785 ENOG4105CVJ phosphoglycerate mutase BA202_08795 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BA202_08805 ENOG4105K56 Transcriptional regulator BA202_08815 ENOG4105CAQ asparagine synthetase BA202_08835 ENOG4105PGM cation diffusion facilitator family transporter BA202_08845 ENOG4105DRR Transcriptional regulator, GntR family BA202_08850 ENOG4108UZ3 Transporter BA202_08855 ENOG4105CKI cobalamin synthesis protein BA202_08860 ENOG4108PJD permease BA202_08875 ENOG4105DFD Na H antiporter BA202_08880 ENOG4105C9Q fumarate hydratase class II BA202_08905 ENOG4107QJQ Mate efflux family protein BA202_08910 ENOG4105EC3 peptidase S51, dipeptidase E BA202_08960 ENOG4106BRA Membrane BA202_08995 ENOG4105CJ1 ABC, transporter BA202_09020 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BA202_09030 ENOG4108IJ0 Aspartate ammonia-lyase BA202_09035 ENOG4105C6K Malic enzyme BA202_09055 ENOG4108SHJ s-layer protein BA202_09060 ENOG4105C0D helicase BA202_09080 ENOG41067QW Transcriptional regulator BA202_09110 ENOG4105FVX BA202_09145 ENOG4105CSR polyphosphate kinase 2 BA202_09165 ENOG4105DXI Major Facilitator superfamily BA202_09180 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BA202_09190 ENOG4105EU0 Major facilitator Superfamily BA202_09195 ENOG4105C6T cysteine synthase BA202_09215 ENOG4105C8J )-transporter BA202_09225 ENOG4105X5K response regulator receiver protein BA202_09230 ENOG4105H67 Protein of unknown function (DUF421) BA202_09245 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BA202_09250 ENOG4105CHR reductase BA202_09255 ENOG4105CM2 brancheD-chain amino acid aminotransferase BA202_09260 ENOG4105C7K acetolactate synthase BA202_09280 ENOG4105C7B Threonine dehydratase BA202_09305 ENOG4105C6X Major Facilitator BA202_09310 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BA202_09325 ENOG4105DY9 regulatoR BA202_09330 ENOG4105CYC Transferase BA202_09355 ENOG41068WN BA202_09375 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BA202_09390 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BA202_09400 ENOG4105C0X amino acid BA202_09425 ENOG4107RHR regulatoR BA202_09435 ENOG4105D9N nucleoside BA202_09440 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BA202_09465 ENOG4107RAQ aminopeptidase BA202_09470 ENOG4107R16 Multicopper oxidase BA202_09545 ENOG4108T5E Copper resistance protein BA202_09550 ENOG4105KTB nuclear export factor GLE1 BA202_09555 ENOG4107RT3 EamA-like transporter family BA202_09560 ENOG4105GZI Transcriptional regulator BA202_09565 ENOG4108Z40 Transcriptional regulator BA202_09570 ENOG4107ZXU DSBA oxidoreductase BA202_09575 ENOG4108TVJ Nitroreductase BA202_09590 ENOG4106F5Q Membrane BA202_09595 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BA202_09605 ENOG4105CKI cobalamin synthesis protein BA202_09620 ENOG4108Z7G MaoC domain protein dehydratase BA202_09625 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BA202_09640 ENOG4105C0Z ABC transporter BA202_09645 ENOG4108IV0 ABC, transporter BA202_09650 ENOG4105C32 Amino acid ABC transporter (Permease) BA202_09660 ENOG4105SKE transcriptional Regulator LysR family BA202_09670 ENOG41090U3 tautomerase BA202_09690 ENOG4105C4M (Ubiquinol oxidase) subunit I BA202_09695 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA202_09700 ENOG4108JJ9 ABC, transporter BA202_09705 ENOG4108JJ8 (ABC) transporter BA202_09715 ENOG4105K64 Glycosyl transferase, family 2 BA202_09725 ENOG4108UT6 Transferase hexapeptide repeat containing protein BA202_09750 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BA202_09780 ENOG4105BZ1 (ABC) transporter BA202_09785 ENOG4105EFI regulatoR BA202_09790 ENOG4105BZU Histidine kinase BA202_09805 ENOG4108VQJ O-methyltransferase BA202_09810 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BA202_09815 ENOG4108ZJ4 polysaccharide deacetylase BA202_09825 ENOG41081VB Hydrolase BA202_09840 ENOG4105D6E homoserine dehydrogenase BA202_09865 ENOG4108KGH TRANSCRIPTIONal BA202_09875 ENOG4107VMI polysaccharide deacetylase BA202_09885 ENOG4105KT7 mgtC SapB transporter BA202_09890 ENOG4105VRR gCN5-related N-acetyltransferase BA202_09895 ENOG4105YWU small acid-soluble spore protein BA202_09905 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BA202_09910 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA202_09955 ENOG4105DQ6 Transposase BA202_09970 ENOG4105KRN Transcriptional regulator, abrb family BA202_09990 ENOG4108KB1 transcriptional regulator, arac family BA202_09995 ENOG4108JP0 extracellular solute-binding protein family 1 BA202_10000 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BA202_10005 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BA202_10010 ENOG4105CT8 Phosphorylase BA202_10015 ENOG4105DKQ ROK family BA202_10020 ENOG4105E70 isomerase BA202_10025 ENOG4105CE4 GlcNAc 6-P deacetylase BA202_10030 ENOG4105DE4 1-phosphofructokinase BA202_10035 ENOG4105D2M Aldolase BA202_10040 ENOG4105ESP cell wall surface anchor family protein BA202_10045 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BA202_10050 ENOG4105YVS arsR family transcriptional regulator BA202_10055 ENOG4105CPC Aldo Keto reductase BA202_10060 ENOG4107XZQ multidrug resistance protein BA202_10100 ENOG4108K88 Membrane BA202_10105 ENOG4108WPJ Ferritin-like domain BA202_10115 ENOG4105DEN Luciferase family BA202_10130 ENOG4105VMI -acetyltransferase BA202_10135 ENOG4107QM2 Aldo Keto reductase BA202_10140 ENOG4105CKI cobalamin synthesis protein BA202_10150 ENOG4105DSE periplasmic solute binding protein BA202_10160 ENOG4105K4T epimerase BA202_10170 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA202_10195 ENOG4105CVJ phosphoglycerate mutase BA202_10215 ENOG4107T5V SNARE associated Golgi BA202_10230 ENOG4108PJD permease BA202_10240 ENOG4108S4H thioesterase Superfamily protein BA202_10245 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BA202_10265 ENOG4105SXS Protein of unknown function (DUF456) BA202_10270 ENOG4105C37 (CBS) domain BA202_10290 ENOG4108Z7R Chaperone CsaA BA202_10310 ENOG4108ZRV stage ii sporulation protein p BA202_10320 ENOG4108VXD carboxy-peptidase BA202_10330 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BA202_10380 ENOG4105D6J arsenicaL-resistance protein BA202_10385 ENOG41082YX Transcriptional regulator, arsr family BA202_10455 ENOG4108X4Q Hydrolase BA202_10465 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BA202_10470 ENOG4107RBS Methyltransferase BA202_10485 ENOG41087PP glycosyltransferase MGT family BA202_10490 ENOG4108JYZ YitT family BA202_10495 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA202_10520 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BA202_10545 ENOG4106PAW secretion accessory protein EsaA YueB BA202_10555 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BA202_10560 ENOG4108MGT Required for secretion of EsxA and EsxB BA202_10645 ENOG4105D7V transposase BA202_10650 ENOG4105KBJ sporulation protein ytfj BA202_10660 ENOG4105DQ6 Transposase BA202_10685 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BA202_10705 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BA202_10715 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BA202_10720 ENOG4105EMN RNA polymerase sigma factor BA202_10735 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BA202_10745 ENOG4105CNW domain protein BA202_10755 ENOG4108V06 Glutathione peroxidase BA202_10770 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA202_10810 ENOG4105MCT stage V sporulation protein S BA202_10825 ENOG4105C5H ABC transporter BA202_10845 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BA202_10850 ENOG4105C4R Atp-dependent dna helicase BA202_10895 ENOG4108FPN Integrase BA202_10930 ENOG4108UUM single-stranded DNA-binding protein BA202_10960 ENOG4107YX5 Pfam:DUF548 BA202_10965 ENOG4105C75 arginyL-tRNA synthetase BA202_10995 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BA202_11000 ENOG4105C5S asparaginyl-tRNA synthetase BA202_11005 ENOG4105C8J )-transporter BA202_11025 ENOG4107XGZ Hydrolase BA202_11030 ENOG4105CY2 Citrate transporter BA202_11035 ENOG4105C0A alcohol dehydrogenase BA202_11050 ENOG4105KD7 acetyltransferase BA202_11055 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) BA202_11060 ENOG410905X membrane-flanked domain protein BA202_11065 ENOG4105CKV Membrane BA202_11075 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BA202_11100 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BA202_11110 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BA202_11130 ENOG4107RVG penicillin-binding protein BA202_11140 ENOG4105E9Q Acyl-transferase BA202_11145 ENOG4108UT2 hemolysin iii BA202_11155 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BA202_11165 ENOG4108RCR degv family BA202_11170 ENOG4105E8R UPF0173 metal-dependent hydrolase BA202_11175 ENOG4108KF3 Electron transport protein SCO1 SenC BA202_11180 ENOG4107Y70 Heat shock protein BA202_11185 ENOG4105CAQ asparagine synthetase BA202_11200 ENOG4108MES Periplasmic binding protein BA202_11205 ENOG4105F0I Aminotransferase BA202_11230 ENOG4107Y70 Heat shock protein BA202_11240 ENOG4105BZU Histidine kinase BA202_11245 ENOG4105WH1 Two component transcriptional regulator luxr family BA202_11250 ENOG4105FQP Beta-lactamase BA202_11255 ENOG4106KNT transcriptional regulator BA202_11285 ENOG4105CMG Carbohydrate kinase BA202_11290 ENOG4105C6Z Gluconate BA202_11300 ENOG4108YV3 Protein of unknown function (DUF2711) BA202_11330 ENOG4108IJ8 ABC transporter BA202_11335 ENOG4105E90 ABC transporter BA202_11370 ENOG4105C37 (CBS) domain BA202_11395 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA202_11410 ENOG4107S4Y M20 DapE family protein YgeY BA202_11415 ENOG4108TSC N-acetyltransferase BA202_11420 ENOG4108JUB Transcriptional regulator BA202_11425 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BA202_11470 ENOG410841Q phosphoesterase PA-phosphatase related protein BA202_11480 ENOG4105SZ6 Thioredoxin BA202_11515 ENOG4108AEY RNA polymerase sigma factor BA202_11545 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BA202_11590 ENOG4105BZ4 penicillin-binding protein BA202_11600 ENOG4105CZM Major Facilitator BA202_11605 ENOG4105W8X HesB YadR YfhF-family protein BA202_11615 ENOG4105DXD 2-methylcitrate dehydratase BA202_11620 ENOG4105CR4 methylisocitrate lyase BA202_11625 ENOG4105C1G acyl-Coa dehydrogenase BA202_11630 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA202_11640 ENOG4105N14 lysine exporter protein LysE YggA BA202_11645 ENOG4105E39 Enoyl-CoA hydratase BA202_11660 ENOG4107RFY SbcCD D subunit BA202_11665 ENOG4105EYH Exonuclease BA202_11690 ENOG4105FCD Major Facilitator BA202_11695 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BA202_11700 ENOG4105E4F Isochorismate synthase BA202_11705 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BA202_11710 ENOG4105WQI isochorismatase BA202_11715 ENOG4105CEY Amp-dependent synthetase and ligase BA202_11720 ENOG4105WQT MbtH domain protein BA202_11725 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_11740 ENOG4105K70 DNA-binding protein BA202_11760 ENOG4105BZG amino acid carrier protein BA202_11775 ENOG4105FE9 pseudouridine synthase BA202_11780 ENOG4105C22 threonyL-tRNA synthetase BA202_11785 ENOG4105C19 ABC transporter BA202_11795 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BA202_11850 ENOG41081I9 integral membrane protein BA202_11865 ENOG4107MII Sugar-specific transcriptional regulator TrmB BA202_11880 ENOG4105EYF MMPL domain protein BA202_11900 ENOG4105WCN acetyltransferase BA202_11925 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BA202_11930 ENOG4105C1Q protoporphyrinogen oxidase BA202_11940 ENOG41068WN BA202_11950 ENOG4105VEQ Cold shock protein BA202_11975 ENOG4107V2S Transcriptional regulator BA202_11980 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA202_11995 ENOG4105BZ1 (ABC) transporter BA202_12000 ENOG4105BZ1 (ABC) transporter BA202_12025 ENOG4108JCI Transcriptional regulator BA202_12085 ENOG4105F32 YngK protein BA202_12110 ENOG4105RD7 BadF BadG BcrA BcrD BA202_12130 ENOG4108INS Transcriptional regulator BA202_12155 ENOG4105C1J atp-dependent rna helicase BA202_12160 ENOG4108RZE Tetr family transcriptional regulator BA202_12175 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BA202_12180 ENOG41088CC tellurite resistance protein tehB BA202_12190 ENOG4108I0C methyltransferase BA202_12195 ENOG4107RA9 decarboxylase BA202_12200 ENOG4105K56 Transcriptional regulator BA202_12230 ENOG4105CIN aminoacyl-histidine dipeptidase BA202_12245 ENOG4105DQ6 Transposase BA202_12250 ENOG4107RVG penicillin-binding protein BA202_12265 ENOG4107RF6 penicillin-binding protein BA202_12270 ENOG4107RF6 penicillin-binding protein BA202_12280 ENOG4105DIN metallophosphoesterase BA202_12290 ENOG4105CJ1 ABC, transporter BA202_12300 ENOG4107Z3H Transcriptional regulator, TetR family BA202_12315 ENOG4105C1G acyl-Coa dehydrogenase BA202_12320 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BA202_12325 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BA202_12330 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BA202_12335 ENOG4105E39 Enoyl-CoA hydratase BA202_12340 ENOG4107QX3 carboxylase BA202_12345 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA202_12355 ENOG4105DQ6 Transposase BA202_12375 ENOG4105DBI uridine monophosphokinase BA202_12405 ENOG4105T9C HD domain BA202_12415 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BA202_12450 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BA202_12465 ENOG4105FQP Beta-lactamase BA202_12475 ENOG4107Y80 Major Facilitator superfamily BA202_12545 ENOG410900G Protein of unknown function (DUF421) BA202_12555 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BA202_12565 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BA202_12640 ENOG4105D6E homoserine dehydrogenase BA202_12655 ENOG4105ETU transcriptional activator (TenA BA202_12725 ENOG410667J hydrolase BA202_12730 ENOG4105BZU Histidine kinase BA202_12735 ENOG4107RF6 penicillin-binding protein BA202_12765 ENOG4108HGU Histidine kinase BA202_12785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_12790 ENOG4105GR3 Histidine kinase BA202_12795 ENOG4105CB2 alcohol dehydrogenase BA202_12800 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BA202_12805 ENOG4105CJN penicillin-binding protein BA202_12810 ENOG4108IG5 Transcriptional regulator BA202_12815 ENOG4105CHR reductase BA202_12855 ENOG4107Y80 Major Facilitator superfamily BA202_12870 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BA202_12895 ENOG4107Y9U Membrane BA202_12940 ENOG4105FCD Major Facilitator BA202_12945 ENOG4105E09 nadh pyrophosphatase BA202_12950 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BA202_12955 ENOG4108Z4K mutator MutT protein BA202_12975 ENOG4108XI2 Domain of unknown function (DUF1963) BA202_13000 ENOG4108NRW Phospholipase, patatin family BA202_13005 ENOG4105KWG Pfam:DUF1696 BA202_13015 ENOG4108YYS metal-dependent hydrolase (By similarity) BA202_13040 ENOG4105PKS Excinuclease abc c subunit domain protein BA202_13075 ENOG4107VFR oxidoreductase BA202_13095 ENOG4105PAD Hydrolase BA202_13110 ENOG4108IUM Glycogen debranching enzyme BA202_13125 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BA202_13130 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BA202_13140 ENOG4105FDR Membrane BA202_13145 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA202_13200 ENOG4105MSI germination protein ypeb BA202_13270 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BA202_13285 ENOG4108MK9 spermidine N(1)-acetyltransferase BA202_13290 ENOG4105E98 transcriptional regulator DeoR family BA202_13310 ENOG4107QKR Dehydrogenase BA202_13320 ENOG4107RUY (E1 component), alpha subunit BA202_13330 ENOG4105E1F short-chain dehydrogenase reductase BA202_13335 ENOG4105RHY Pfam:UPF0157 BA202_13340 ENOG4105DBI uridine monophosphokinase BA202_13355 ENOG4108TIT dATP pyrophosphohydrolase BA202_13375 ENOG4107SQ8 Glycine betaine BA202_13380 ENOG4108IJ7 Glycine betaine BA202_13410 ENOG41082BV acetyltransferase BA202_13415 ENOG41087PP glycosyltransferase MGT family BA202_13435 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA202_13440 ENOG4105MSB protein, conserved in bacteria BA202_13450 ENOG4105QZY s-layer domain protein BA202_13470 ENOG4108Z7F N-acetyltransferase BA202_13480 ENOG4105EEM helicase BA202_13500 ENOG4105C9U ATP-dependent DNA helicase RecQ BA202_13555 ENOG4108M1A Chitin-binding protein BA202_13575 ENOG4105BZG amino acid carrier protein BA202_13580 ENOG4105C26 Dehydrogenase BA202_13585 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA202_13590 ENOG4105CTU Proline racemase BA202_13595 ENOG4105CTU Proline racemase BA202_13600 ENOG41080HI glycine oxidase BA202_13610 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BA202_13640 ENOG4107T5V SNARE associated Golgi BA202_13655 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BA202_13660 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BA202_13675 ENOG4105DTQ mandelate racemase muconate lactonizing BA202_13725 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BA202_13730 ENOG4105BZU Histidine kinase BA202_13735 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_13760 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BA202_13775 ENOG4105DPN Oligoendopeptidase f BA202_13785 ENOG4105EPR degv family BA202_13830 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BA202_13835 ENOG4106K7D Major facilitator family transporter BA202_13855 ENOG4107BMA Transglycosylase associated protein BA202_13870 ENOG41089UC methyltransferase, type 11 BA202_13905 ENOG4105CHM Aminotransferase BA202_13920 ENOG4108ZMI UPF0477 protein BA202_13940 ENOG4105DVE abc transporter atp-binding protein BA202_13990 ENOG4105C02 permease BA202_14005 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BA202_14010 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BA202_14015 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BA202_14060 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BA202_14110 ENOG4107VMI polysaccharide deacetylase BA202_14120 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BA202_14130 ENOG4106ETB IIa component BA202_14135 ENOG4108ZCF integral membrane protein BA202_14140 ENOG4105E0M Sulfatase BA202_14145 ENOG4105C5H ABC transporter BA202_14160 ENOG4105EYF MMPL domain protein BA202_14165 ENOG41082JN Transcriptional regulator BA202_14195 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BA202_14235 ENOG41069ER domain protein BA202_14260 ENOG4105D4B ABC, transporter BA202_14265 ENOG4105F5R ABC transporter BA202_14270 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BA202_14280 ENOG4105DKT Transcriptional regulator BA202_14285 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BA202_14295 ENOG41061GT Aldolase BA202_14320 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BA202_14350 ENOG4105II7 pyrroline-5-carboxylate reductase BA202_14360 ENOG4107258 Transcriptional regulator BA202_14370 ENOG4105E0Y RtcB Protein BA202_14375 ENOG4105ECK Fatty Acid Desaturase BA202_14385 ENOG4105G6Z alkaline phosphatase BA202_14395 ENOG4105VMP Transcriptional regulator BA202_14405 ENOG41090T1 Membrane BA202_14415 ENOG4108WCX response regulator BA202_14435 ENOG4105KNA -acetyltransferase BA202_14465 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA202_14485 ENOG4105C8Y Acetylornithine aminotransferase BA202_14515 ENOG4108W5M transcriptional regulator BA202_14545 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BA202_14590 ENOG41090AA BA202_14595 ENOG4106BHF BA202_14625 ENOG4108IBT Inherit from COG: transposase BA202_14645 ENOG4108TVJ Nitroreductase BA202_14650 ENOG4105FS7 Transcriptional regulator BA202_14665 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BA202_14675 ENOG4105CMR udp-glucose 4-epimerase BA202_14680 ENOG4105C19 ABC transporter BA202_14725 ENOG4108XET gCN5-related N-acetyltransferase BA202_14790 ENOG410635A Membrane BA202_14800 ENOG4108IQI permease BA202_14820 ENOG4107ZY0 Phenazine biosynthesis-like protein BA202_14850 ENOG4107RF6 penicillin-binding protein BA202_14890 ENOG4105P4J Allophanate hydrolase, subunit 1 BA202_14895 ENOG4107258 Transcriptional regulator BA202_14905 ENOG4106N3A copper homeostasis protein cutc BA202_14910 ENOG4108ZRV stage ii sporulation protein p BA202_14915 ENOG4105FDT acyl-CoA dehydrogenase BA202_14930 ENOG4105DWD nucleoside recognition domain protein BA202_14955 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BA202_14960 ENOG41087PP glycosyltransferase MGT family BA202_14980 ENOG4105E2A Dehydrogenase BA202_14985 ENOG4105EB3 Histidine kinase BA202_14990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_15015 ENOG4105CVP deoxyribo-dipyrimidine photolyase BA202_15035 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BA202_15050 ENOG4108TWJ NADH dehydrogenase subunit 5 BA202_15055 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BA202_15070 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BA202_15075 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BA202_15080 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BA202_15095 ENOG4105Z7P Acetyltransferase (GNAT) family BA202_15115 ENOG4105DET Rhamnulokinase BA202_15120 ENOG4107W7X Aldolase BA202_15130 ENOG4105CNN ABC, transporter BA202_15135 ENOG4105C2J ABC transporter BA202_15140 ENOG4105NWF RbsD or FucU transport BA202_15155 ENOG4105D6J arsenicaL-resistance protein BA202_15160 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_15165 ENOG41085FC arsR family transcriptional regulator BA202_15180 ENOG4105NAE bifunctional deaminase-reductase domain protein BA202_15195 ENOG4105EKQ RNA-directed DNA polymerase BA202_15205 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BA202_15235 ENOG4107P5I polyketide synthase BA202_15240 ENOG4108IG5 Transcriptional regulator BA202_15245 ENOG4105F27 Major Facilitator BA202_15250 ENOG4105M4P Tetr family transcriptional regulator BA202_15255 ENOG4105CHR reductase BA202_15300 ENOG4107A6P BA202_15325 ENOG4105N0V mono-oxygenase ydhR BA202_15340 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BA202_15345 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_15445 ENOG4105K6H D-cysteine desulfhydrase BA202_15465 ENOG4105JQZ Methyltransferase BA202_15480 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BA202_15485 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BA202_15505 ENOG4105BZU Histidine kinase BA202_15520 ENOG4108U05 Transcriptional regulator BA202_15525 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BA202_15535 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BA202_15565 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BA202_15580 ENOG4108JQ1 Dehydrogenase BA202_15600 ENOG41082W1 Cupin 2, conserved barrel domain protein BA202_15605 ENOG410874W AraC family transcriptional regulator BA202_15625 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BA202_15895 ENOG4108ISG Major Facilitator BA202_15910 ENOG4107MII Sugar-specific transcriptional regulator TrmB BA202_15915 ENOG4105CZM Major Facilitator BA202_15930 ENOG4105CRW Short chain fatty acid transporter BA202_15950 ENOG4105DYS nad(p)h dehydrogenase (quinone) BA202_15980 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BA202_16010 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BA202_16030 ENOG4108Z66 YbaK ebsC protein BA202_16065 ENOG4108PSK reductase BA202_16075 ENOG4105CJ1 ABC, transporter BA202_16130 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_16135 ENOG4105DKQ ROK family BA202_16140 ENOG4108UW5 maltose o-acetyltransferase BA202_16145 ENOG4105C31 Tryptophanyl-tRNA synthetase BA202_16185 ENOG4105DMQ Methyltransferase BA202_16195 ENOG4105EV4 Multidrug resistance protein mdtH BA202_16220 ENOG4105C37 (CBS) domain BA202_16235 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BA202_16240 ENOG4105FAW cDP-glucose 4,6-dehydratase BA202_16275 ENOG4105DDN Pentapeptide repeat-containing protein BA202_16280 ENOG4105XDF Protein of unknown function (DUF1272) BA202_16285 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BA202_16290 ENOG4105CMG Carbohydrate kinase BA202_16295 ENOG4105C6Z Gluconate BA202_16300 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BA202_16315 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BA202_16330 ENOG4105C44 Serine transporter BA202_16360 ENOG4108TZY GntR Family Transcriptional Regulator BA202_16365 ENOG4105D9R oxidoreductase BA202_16390 ENOG4105JAB phenazine biosynthesis protein, phzf family BA202_16400 ENOG4105CHR reductase BA202_16415 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BA202_16420 ENOG4105KVH Transcriptional regulator BA202_16455 ENOG4105KAF membrAne BA202_16480 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BA202_16525 ENOG4105H3G oxidoreductase BA202_16560 ENOG4105CIS alcohol dehydrogenase BA202_16595 ENOG4108TN2 lmbE family BA202_16605 ENOG4107R3E Citrate transporter BA202_16620 ENOG4108MES Periplasmic binding protein BA202_16625 ENOG4105EHG Permease protein BA202_16630 ENOG4105DQ5 transport system permease protein BA202_16635 ENOG4105NX3 Membrane BA202_16680 ENOG4105VZ8 Transcriptional regulator BA202_16685 ENOG4105VZ8 Transcriptional regulator BA202_16695 ENOG4107CUJ Protein of unknown function (DUF2690) BA202_16705 ENOG4107V2S Transcriptional regulator BA202_16720 ENOG4105DQ6 Transposase BA202_16735 ENOG4105C98 muts2 protein BA202_16740 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BA202_16745 ENOG4105DPN Oligoendopeptidase f BA202_16765 ENOG4108A04 Beta-lactamase BA202_16795 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BA202_16805 ENOG4105EEM helicase BA202_16820 ENOG41082BM Transcriptional regulator, arsr family BA202_16825 ENOG4105CIS alcohol dehydrogenase BA202_16835 ENOG4107JM4 Tetratricopeptide repeat BA202_16865 ENOG4105C09 Bile acid BA202_16870 ENOG4105CQB FAD linked oxidase domain protein BA202_16905 ENOG4105KT7 mgtC SapB transporter BA202_16920 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_16925 ENOG4105EAB amino acid AbC transporter BA202_16935 ENOG4108HW4 amino acid AbC transporter BA202_16940 ENOG41073R8 VanW family BA202_16950 ENOG4108R1P BA202_16955 ENOG4105FEA Spore maturation protein BA202_16960 ENOG4105FEA Spore maturation protein BA202_16965 ENOG4105FEA Spore maturation protein BA202_16980 ENOG4108R1P BA202_17000 ENOG4105VEQ Cold shock protein BA202_17020 ENOG4105M6F mutator MutT protein BA202_17040 ENOG410904N short-chain dehydrogenase reductase BA202_17050 ENOG4106IQC argininosuccinate lyase BA202_17065 ENOG4108IA2 Sodium pantothenate symporter BA202_17115 ENOG4105CHR reductase BA202_17125 ENOG4105EWU Squalene--hopene cyclase BA202_17135 ENOG4105FR1 rard protein BA202_17140 ENOG410696E Membrane BA202_17155 ENOG4105D1F ATP-binding protein BA202_17165 ENOG4108ZAF Molybdopterin BA202_17170 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA202_17175 ENOG4105D06 uba thif-type nad fad binding protein BA202_17180 ENOG4105TMB Formate nitrite transporter BA202_17190 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BA202_17195 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BA202_17205 ENOG4108JB9 formate dehydrogenase BA202_17275 ENOG4107QJT sodium dicarboxylate symporter BA202_17280 ENOG4108KGH TRANSCRIPTIONal BA202_17290 ENOG4105EMN RNA polymerase sigma factor BA202_17305 ENOG4105CIG ABC transporter BA202_17325 ENOG4105D9R oxidoreductase BA202_17335 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BA202_17345 ENOG4105K4P CoA-binding domain protein BA202_17350 ENOG4105C0H protease BA202_17355 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_17365 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BA202_17375 ENOG4105W8X HesB YadR YfhF-family protein BA202_17405 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BA202_17410 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BA202_17420 ENOG4105BZ1 (ABC) transporter BA202_17425 ENOG4108I0Z Aconitate hydratase BA202_17455 ENOG4105E5W Transporter BA202_17465 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BA202_17495 ENOG4107F3J Amp-dependent synthetase and ligase BA202_17500 ENOG4107ZYJ bioY protein BA202_17505 ENOG4105CEY Amp-dependent synthetase and ligase BA202_17520 ENOG4108IMY Transcriptional regulator BA202_17560 ENOG4107AYK membrAne BA202_17570 ENOG4105BZU Histidine kinase BA202_17575 ENOG4105FBA Phospholipase Carboxylesterase BA202_17580 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BA202_17585 ENOG4105CK7 Sodium proline symporter BA202_17595 ENOG4105CBC glutamate synthase BA202_17600 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BA202_17605 ENOG4108903 Formimidoylglutamase BA202_17630 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BA202_17675 ENOG4105EKQ RNA-directed DNA polymerase BA202_17700 ENOG4107QIV Cytochrome c biogenesis protein BA202_17710 ENOG4105CH2 amidohydrolase BA202_17720 ENOG4105CJ1 ABC, transporter BA202_17730 ENOG4107RSM transcriptional regulator BA202_17740 ENOG41067MG lrgb family BA202_17775 ENOG4105BZ1 (ABC) transporter BA202_17780 ENOG4105BZ1 (ABC) transporter BA202_17815 ENOG4108HW3 (ABC) transporter BA202_17820 ENOG4105CGH 5'-nucleotidase BA202_17830 ENOG4108SVB resolvase BA202_17850 ENOG4105K7K Transcriptional regulator BA202_17855 ENOG4105C5F glutamine synthetase BA202_17860 ENOG4105KV4 Transcriptional regulator BA202_17865 ENOG4105CXI aluminum resistance protein BA202_17870 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BA202_17875 ENOG4105EN6 Membrane BA202_17880 ENOG4106F1P AAA ATPase, central domain protein BA202_17910 ENOG41069ER domain protein BA202_17915 ENOG4105DM4 PTS System BA202_17920 ENOG4105DE4 1-phosphofructokinase BA202_17925 ENOG4105E98 transcriptional regulator DeoR family BA202_17930 ENOG4107QW4 alcohol dehydrogenase BA202_17935 ENOG4108SJC Membrane BA202_17950 ENOG4105C85 amino acid BA202_17970 ENOG4105TMB Formate nitrite transporter BA202_17975 ENOG4105K70 DNA-binding protein BA202_17980 ENOG4105C59 p-type ATPase BA202_17985 ENOG410681U heavy metal transport detoxification protein BA202_17990 ENOG4105VPX protein, conserved in bacteria BA202_18000 ENOG4105PGM cation diffusion facilitator family transporter BA202_18020 ENOG4105NIV Esterase BA202_18025 ENOG4105E0A ABC, transporter BA202_18050 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BA202_18055 ENOG4105D03 DNA-3-methyladenine glycosylase II BA202_18085 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_18090 ENOG4105BZU Histidine kinase BA202_18145 ENOG4105F0V Cell wall hydrolase BA202_18150 ENOG4105E0M Sulfatase BA202_18155 ENOG410890F Dynamin family BA202_18165 ENOG4107QHE Choloylglycine hydrolase BA202_18180 ENOG4105DQ6 Transposase BA202_18205 ENOG4105DQU oxidoreductase, subunit beta BA202_18210 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BA202_18215 ENOG4108IGT Dipeptidase BA202_18220 ENOG4105MCT stage V sporulation protein S BA202_18225 ENOG4105D48 metallophosphoesterase BA202_18250 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BA202_18265 ENOG4105XZV Protein of unknown function (DUF3243) BA202_18270 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BA202_18290 ENOG4105UIB (ABC) transporter BA202_18295 ENOG4108JQ9 ABC transporter BA202_18300 ENOG4105DIH basic membrane BA202_18305 ENOG4105FDP GntR family transcriptional regulator BA202_18310 ENOG4107QZI cell division protein FtsK BA202_18320 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BA202_18335 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA202_18345 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BA202_18350 ENOG4108S0H Dipicolinic acid synthetase, b subunit BA202_18355 ENOG4105E35 Dipicolinate synthase subunit A BA202_18365 ENOG4105C1V Peptidase, M16 BA202_18385 ENOG4105DTN riboflavin biosynthesis protein ribF BA202_18400 ENOG4105W7A Protein of unknown function (DUF503) BA202_18410 ENOG4105VHM ribosomal protein BA202_18415 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BA202_18420 ENOG4105CHV Transcription elongation factor NusA BA202_18430 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BA202_18440 ENOG4105DZP Membrane-associated zinc metalloprotease BA202_18450 ENOG4105KNE Phosphatidate cytidylyltransferase BA202_18495 ENOG4108HE4 integrase family BA202_18505 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BA202_18510 ENOG4105C79 DNA protecting protein DprA BA202_18515 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BA202_18530 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BA202_18555 ENOG4105VB6 UPF0109 protein BA202_18575 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BA202_18580 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BA202_18595 ENOG4105CHR reductase BA202_18600 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BA202_18615 ENOG4105CB5 ATP-dependent DNA helicase recG BA202_18620 ENOG4105DP4 dak2 domain fusion protein ylov BA202_18625 ENOG4108ZAA Alkaline-shock protein BA202_18640 ENOG4105FJ0 thiamine BA202_18645 ENOG4105DJV ribulose-phosphate 3-epimerase BA202_18655 ENOG4105D9P serine threonine protein kinase BA202_18660 ENOG4108ZF3 Phosphatase BA202_18670 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BA202_18680 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BA202_18685 ENOG4105C25 Primosomal protein n' BA202_18690 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BA202_18710 ENOG4105DSJ YicC domain protein BA202_18720 ENOG4105F23 Fibronectin-binding protein BA202_18730 ENOG4105DC7 peptidase M24 BA202_18805 ENOG4105C34 Pseudouridine synthase BA202_18830 ENOG4105DBK s4 domain protein BA202_18835 ENOG41067XK integral membrane protein BA202_18845 ENOG4105DFA alanine racemase domain protein BA202_18850 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BA202_18855 ENOG4105WR5 sporulation protein, YlmC YmxH family BA202_18865 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_18875 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BA202_18880 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BA202_18885 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BA202_18900 ENOG4105CNI cell division protein FtsW BA202_18915 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BA202_18920 ENOG4105CJN penicillin-binding protein BA202_18925 ENOG4105CJN penicillin-binding protein BA202_18930 ENOG41068DC Essential cell division protein (By similarity) BA202_18965 ENOG4105KNH Nucleic acid-binding protein BA202_18975 ENOG41063PX domain protein BA202_18980 ENOG4105D78 K07001 NTE family protein BA202_18985 ENOG4105H20 Sporulation integral membrane protein YlbJ BA202_18995 ENOG4106H78 methyltransferase BA202_19015 ENOG4107TB6 phosphoglycerate mutase BA202_19030 ENOG4106UY4 Inherit from COG: Scp-like extracellular BA202_19080 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BA202_19085 ENOG4105CNI cell division protein FtsW BA202_19100 ENOG4108IAB Phoh family BA202_19120 ENOG4105QA2 BA202_19125 ENOG4105CI3 gtp-binding protein typa BA202_19135 ENOG4105ECY inositol monophosphatase BA202_19155 ENOG4105CXN decarboxylase BA202_19205 ENOG4105CPP Dehydrogenase, E1 component BA202_19220 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BA202_19225 ENOG4108X4Q Hydrolase BA202_19235 ENOG4105CN5 Metallo-Beta-Lactamase BA202_19240 ENOG4107ZYR domain protein BA202_19275 ENOG4108XRC Protein of unknown function (DUF458) BA202_19285 ENOG4107IN1 Protein of unknown function (DUF1797) BA202_19300 ENOG4105EPM Diguanylate phosphodiesterase BA202_19305 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BA202_19320 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BA202_19330 ENOG4105UIN BA202_19390 ENOG4108HGU Histidine kinase BA202_19400 ENOG4105CHM Aminotransferase BA202_19405 ENOG4105FKQ transcriptional regulator BA202_19410 ENOG4105EG2 ABC transporter, permease BA202_19420 ENOG4107FKK extracellular solute-binding protein family 1 BA202_19430 ENOG4105CG3 alpha amylase, catalytic region BA202_19475 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BA202_19480 ENOG4105CHU acetyl-coa acetyltransferase BA202_19520 ENOG4105K7K Transcriptional regulator BA202_19525 ENOG4105DTD Dehydrogenase BA202_19540 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BA202_19580 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BA202_19590 ENOG4106TD9 Diguanylate cyclase BA202_19610 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BA202_19625 ENOG4105CID antiterminator BA202_19635 ENOG4105FDP GntR family transcriptional regulator BA202_19645 ENOG4105CE4 GlcNAc 6-P deacetylase BA202_19690 ENOG4107ZE5 PPIases accelerate the folding of proteins BA202_19695 ENOG4105PTM secreted protein BA202_19700 ENOG4105J7I hydrolase BA202_19710 ENOG4105G6R Stage v sporulation protein ae BA202_19720 ENOG4105CZ3 stage V sporulation protein ad BA202_19725 ENOG41090VF Stage v sporulation protein ac BA202_19745 ENOG4105C8J )-transporter BA202_19750 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_19760 ENOG41082AN stage II sporulation protein BA202_19765 ENOG4105DZ1 carboxypeptidase BA202_19770 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BA202_19775 ENOG4105DVE abc transporter atp-binding protein BA202_19790 ENOG4105DQ6 Transposase BA202_19825 ENOG4105DQ6 Transposase BA202_19830 ENOG4105D7N magnesium and cobalt transport protein CorA BA202_19855 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA202_19865 ENOG4105I3K Ferric uptake regulator, Fur family BA202_19870 ENOG4105MZ9 stage II sporulation protein m BA202_19890 ENOG4105CPC Aldo Keto reductase BA202_19900 ENOG4105RHY Pfam:UPF0157 BA202_19920 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BA202_19930 ENOG4105ETE Transcriptional regulator (LacI family BA202_19935 ENOG4108YM7 Gcn5-related n-acetyltransferase BA202_19955 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BA202_19960 ENOG4108R6K riboflavin synthase, subunit alpha BA202_19985 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA202_19990 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BA202_20005 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BA202_20015 ENOG4105DFD Na H antiporter BA202_20020 ENOG4105CGH 5'-nucleotidase BA202_20075 ENOG4108IXY short-chain dehydrogenase reductase BA202_20080 ENOG41069FQ Metallo-beta-lactamase superfamily BA202_20085 ENOG4105II7 pyrroline-5-carboxylate reductase BA202_20090 ENOG4105EJQ L-serine dehydratase BA202_20120 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BA202_20130 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BA202_20140 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BA202_20145 ENOG4105D9U N-acetyltransferase BA202_20160 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BA202_20165 ENOG4108QEG Membrane BA202_20170 ENOG4105CDA abc transporter atp-binding protein BA202_20175 ENOG4105E5Q amino acid AbC transporter BA202_20180 ENOG4108HW3 (ABC) transporter BA202_20195 ENOG4105G7B Protein of unknown function (DUF2992) BA202_20200 ENOG4105E09 nadh pyrophosphatase BA202_20205 ENOG4108QY0 Membrane BA202_20220 ENOG4105C7S Dehydrogenase BA202_20225 ENOG4105CPP Dehydrogenase, E1 component BA202_20245 ENOG4107RDP Dehydrogenase BA202_20260 ENOG4108JUB Transcriptional regulator BA202_20265 ENOG4106CCJ Protein of unknown function (DUF2627) BA202_20270 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BA202_20280 ENOG4107QQR Sporulation BA202_20290 ENOG4105S1Z Stage IV sporulation protein B BA202_20295 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BA202_20305 ENOG4105DX0 Hemolysin A BA202_20315 ENOG4105CTB Polyprenyl synthetase BA202_20340 ENOG4108ZSR alkaline shock protein BA202_20345 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BA202_20370 ENOG410644B Stage III sporulation protein af BA202_20380 ENOG4105KQ4 Stage iii sporulation protein ad BA202_20385 ENOG4108CQH stage III sporulation protein AC BA202_20390 ENOG4105KR5 Stage iii sporulation protein BA202_20395 ENOG4105CD2 stage iii sporulation protein aa BA202_20420 ENOG4105DC7 peptidase M24 BA202_20435 ENOG4105CBJ Metal-dependent enzyme BA202_20445 ENOG4107YBY Hydrolase BA202_20465 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BA202_20470 ENOG4105WZW rhodanese family BA202_20490 ENOG41080TC multidrug resistance protein BA202_20530 ENOG4105CJ1 ABC, transporter BA202_20535 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BA202_20565 ENOG4105C0D helicase BA202_20680 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BA202_20690 ENOG4107XZC Restriction modification system DNA (Specificity BA202_20705 ENOG4107SCJ type I restriction enzyme EcoKI subunit R BA202_20800 ENOG4105C3R Methionine synthase BA202_20810 ENOG4105C28 cystathionine BA202_20815 ENOG4105C28 cystathionine BA202_20835 ENOG4105C5X domain protein BA202_20845 ENOG4105DKQ ROK family BA202_20855 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BA202_20870 ENOG4108UTW Plays a role in the regulation of phosphate uptake BA202_20875 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BA202_20880 ENOG4105E2Z phosphate ABC transporter (Permease BA202_20885 ENOG4105C8U phosphate abc transporter BA202_20890 ENOG4105PWN phosphate abc transporter BA202_20895 ENOG4107RF6 penicillin-binding protein BA202_20905 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA202_20930 ENOG4105N80 Ferric uptake regulator, Fur family BA202_20940 ENOG4105FDK ABC transporter BA202_20945 ENOG4108JYZ YitT family BA202_20950 ENOG41069ZM Protein of unknown function (DUF2624) BA202_20975 ENOG4105EGD dinuclear metal center protein, YbgI family BA202_20990 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_20995 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BA202_21030 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BA202_21035 ENOG4105KG3 cytidine deaminase BA202_21040 ENOG4107YR5 Diacylglycerol kinase BA202_21050 ENOG4105CTJ Metal Dependent Phosphohydrolase BA202_21055 ENOG4105C9A Phoh family BA202_21070 ENOG41068P3 sporulation protein YqfC BA202_21075 ENOG4105KTH gatB Yqey BA202_21085 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BA202_21090 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BA202_21120 ENOG4105CSA Coproporphyrinogen iii oxidase BA202_21125 ENOG4105KVH Transcriptional regulator BA202_21150 ENOG4105TQK DNA polymerase iii, delta' subunit BA202_21160 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BA202_21165 ENOG4108UK2 deaminase BA202_21170 ENOG4105KQC Competence protein BA202_21180 ENOG4105DXX methyltransferase BA202_21190 ENOG4108WF2 Metal Dependent Phosphohydrolase BA202_21200 ENOG410812S Rna-binding protein BA202_21210 ENOG4105CQW ribosome biogenesis GTPase YqeH BA202_21215 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BA202_21230 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_21260 ENOG4105G6Z alkaline phosphatase BA202_21270 ENOG4108MUZ hydrolase BA202_21305 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BA202_21310 ENOG4105MIR Phenylalanine 4-monooxygenase BA202_21320 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_21360 ENOG4105S6R Iron-hydroxamate transporter permease subunit BA202_21365 ENOG4108HUF Transporter BA202_21375 ENOG4108EKI Dehydrogenase BA202_21380 ENOG4105C28 cystathionine BA202_21410 ENOG4107XRG penicillin-binding protein BA202_21425 ENOG4105CFP Peptidase U32 BA202_21430 ENOG4105XYU peptidase (U32 family) BA202_21435 ENOG4108VQJ O-methyltransferase BA202_21440 ENOG4105HHA aminodeoxychorismate lyase BA202_21465 ENOG4105C02 permease BA202_21480 ENOG41060CR BA202_21485 ENOG4105C7H Helicase, RecD TraA family BA202_21500 ENOG4105C3J Cysteine desulfurase BA202_21510 ENOG4105D1H recombination factor protein RarA BA202_21515 ENOG4108VCI transcription factor, rsfa family BA202_21525 ENOG4105CUZ uba thif-type nad fad binding protein BA202_21550 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BA202_21565 ENOG4105EKQ RNA-directed DNA polymerase BA202_21575 ENOG41076HS cation diffusion facilitator family transporter BA202_21580 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BA202_21590 ENOG4105CKP Polysaccharide Biosynthesis Protein BA202_21595 ENOG4108QG2 Membrane BA202_21605 ENOG4105VIE preprotein translocase, subunit YajC BA202_21620 ENOG41061AI Protein of unknown function (DUF2905) BA202_21660 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BA202_21665 ENOG4108IYU L-aspartate oxidase BA202_21680 ENOG4108RPX mosc domain containing protein BA202_21690 ENOG4105CQC Prephenate dehydratase BA202_21710 ENOG4105EWM Histidine kinase BA202_21735 ENOG4105X36 (ribosomal) protein BA202_21745 ENOG4105C03 ribonuclease BA202_21760 ENOG4107QMS site-determining protein BA202_21775 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BA202_21780 ENOG4105DFF Rod shape-determining protein mreb BA202_21800 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BA202_21815 ENOG41068KH stage VI sporulation protein D BA202_21825 ENOG4105D52 delta-aminolevulinic acid dehydratase BA202_21850 ENOG4105K56 Transcriptional regulator BA202_21870 ENOG4108IUQ atp-dependent protease BA202_21900 ENOG4108QCI YvbH-like oligomerisation region BA202_21920 ENOG4105M59 Phosphodiesterase, mj0936 family BA202_21935 ENOG4108XJQ germination protein BA202_21945 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_21955 ENOG4105KBX Transcriptional regulator, TetR family BA202_21965 ENOG4105PFC Transcriptional regulator BA202_21975 ENOG4105DZC cytosine deaminase BA202_21980 ENOG41067S9 phage shock protein C, PspC BA202_21985 ENOG4108JCI Transcriptional regulator BA202_21995 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BA202_22000 ENOG4108Z40 Transcriptional regulator BA202_22005 ENOG4105RHA ABC transporter, permease BA202_22010 ENOG4108IUX (ABC) transporter BA202_22015 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BA202_22020 ENOG4105ER2 Ompa motb domain protein BA202_22025 ENOG4105E14 MotA TolQ exbB proton channel BA202_22030 ENOG4108VXD carboxy-peptidase BA202_22040 ENOG4105E33 succinate dehydrogenase BA202_22050 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BA202_22065 ENOG4105K63 Thioredoxin BA202_22070 ENOG4105C10 Electron transfer flavoprotein BA202_22075 ENOG4105BZJ Electron transfer flavoprotein BA202_22080 ENOG41060WC Enoyl-CoA hydratase BA202_22085 ENOG4107Z3H Transcriptional regulator, TetR family BA202_22090 ENOG4105CEY Amp-dependent synthetase and ligase BA202_22135 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA202_22150 ENOG4105DR4 Methyltransferase BA202_22160 ENOG4105KFN sortase, SrtB family BA202_22165 ENOG4105E0A ABC, transporter BA202_22180 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BA202_22185 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BA202_22195 ENOG4105FE9 pseudouridine synthase BA202_22210 ENOG4105DCG PHP domain protein BA202_22265 ENOG4108RWN rrna methyltransferase BA202_22295 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_22300 ENOG4105CW7 secretion protein, HlyD family BA202_22305 ENOG4108JGH Tetr family transcriptional regulator BA202_22310 ENOG4105CN9 Peptidase m42 family protein BA202_22330 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BA202_22335 ENOG4105C22 threonyL-tRNA synthetase BA202_22340 ENOG4108TDW sporulation protein YtxC BA202_22360 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BA202_22365 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BA202_22385 ENOG4105C2M dna polymerase I BA202_22390 ENOG4105BZU Histidine kinase BA202_22395 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA202_22415 ENOG4108HMX isocitrate dehydrogenase (NADP) BA202_22420 ENOG4105BZN citrate synthase BA202_22435 ENOG4108REF Sporulation integral membrane protein ytvi BA202_22440 ENOG4105FS0 cytoplasmic membrane protein BA202_22465 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BA202_22470 ENOG4105C6K Malic enzyme BA202_22475 ENOG4105C0B DNA polymerase III (alpha subunit) BA202_22480 ENOG4105VV2 BA202_22490 ENOG4105SFS phosphoesterase RecJ domain protein BA202_22530 ENOG4105DC7 peptidase M24 BA202_22575 ENOG41082W1 Cupin 2, conserved barrel domain protein BA202_22585 ENOG4105VZ8 Transcriptional regulator BA202_22605 ENOG4107YZX Universal stress protein BA202_22650 ENOG4108JYZ YitT family BA202_22680 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BA202_22685 ENOG4105KBJ sporulation protein ytfj BA202_22700 ENOG4105EFZ amidohydrolase BA202_22710 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BA202_22735 ENOG4105C5Q Transcriptional regulator BA202_22745 ENOG4105U5Y Transcriptional regulator BA202_22755 ENOG4105C28 cystathionine BA202_22765 ENOG4108IBT Inherit from COG: transposase BA202_22800 ENOG4105F1V Acetoin utilization protein BA202_22805 ENOG4105W87 Cbs domain BA202_22810 ENOG4105DGU Histone deacetylase BA202_22825 ENOG4105EP9 oxidoreductase BA202_22855 ENOG4105ETE Transcriptional regulator (LacI family BA202_22880 ENOG4105C88 aminopeptidase BA202_22930 ENOG4108VDD TRNA binding domain protein BA202_22960 ENOG4105C8F Beta-lactamase domain protein BA202_22975 ENOG4108V15 phosphotransferase enzyme family BA202_22980 ENOG4108IUM Glycogen debranching enzyme BA202_22995 ENOG4107QSE Dipeptidase BA202_23000 ENOG4105YW5 deoR family transcriptional regulator BA202_23015 ENOG4105CBX hi0933 family BA202_23050 ENOG4108VJ1 Transcriptional regulator (CarD family BA202_23055 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BA202_23075 ENOG4108ZAF Molybdopterin BA202_23085 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BA202_23090 ENOG4105CVM Molybdenum cofactor synthesis domain protein BA202_23100 ENOG4105D06 uba thif-type nad fad binding protein BA202_23105 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BA202_23125 ENOG41085GJ domain protein BA202_23135 ENOG4105DWV Homoserine O-trans-acetylase BA202_23145 ENOG4108B31 Spore germination protein BA202_23180 ENOG410605W Major Facilitator BA202_23185 ENOG4107S91 Sodium hydrogen exchanger BA202_23190 ENOG4105NCW Trka-c domain protein BA202_23205 ENOG4105C19 ABC transporter BA202_23225 ENOG4105N5T Radical SAM Protein BA202_23235 ENOG4105CIG ABC transporter BA202_23270 ENOG4105E8V Alpha Beta Hydrolase Fold protein BA202_23275 ENOG4108Z0R Transferase BA202_23280 ENOG4105YVM Phosphoesterase, PA-phosphatase related BA202_23285 ENOG4105BZF Glycosyl transferase (Group 1 BA202_23295 ENOG4108RIR Molybdenum cofactor biosynthesis protein BA202_23310 ENOG4108MK9 spermidine N(1)-acetyltransferase BA202_23355 ENOG4105EGD dinuclear metal center protein, YbgI family BA202_23365 ENOG4105BZU Histidine kinase BA202_23370 ENOG4105BZU Histidine kinase BA202_23375 ENOG4107S9D Alpha beta hydrolase BA202_23380 ENOG4107T7U Sulfatase BA202_23400 ENOG4105D2X ABC transporter substrate-binding protein BA202_23410 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BA202_23465 ENOG4108V2W Carbonate dehydratase BA202_23470 ENOG4105C4M (Ubiquinol oxidase) subunit I BA202_23475 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BA202_23515 ENOG41087YS Phage shock protein A BA202_23545 ENOG4105BZU Histidine kinase BA202_23550 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_23580 ENOG4108UGV hypoxanthine phosphoribosyltransferase BA202_23585 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BA202_23610 ENOG4105C19 ABC transporter BA202_23625 ENOG4107ZTW SNARE associated Golgi BA202_23640 ENOG4105C19 ABC transporter BA202_23645 ENOG41086D8 Transcriptional regulator BA202_23655 ENOG41082BM Transcriptional regulator, arsr family BA202_23705 ENOG4105C6Z Gluconate BA202_23710 ENOG4105FDP GntR family transcriptional regulator BA202_23730 ENOG41069H0 dihydroorotase EC 3.5.2.3 BA202_23750 ENOG4105DTQ mandelate racemase muconate lactonizing BA202_23760 ENOG4108IPT Naphthoate synthase BA202_23765 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BA202_23775 ENOG4105E4F Isochorismate synthase BA202_23780 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BA202_23790 ENOG4105VEQ Cold shock protein BA202_23850 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BA202_23950 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BA202_23985 ENOG4105KT7 mgtC SapB transporter BA202_23990 ENOG4107PBV potassium channel BA202_24010 ENOG4105WG9 Conserved Protein BA202_24020 ENOG4105CHM Aminotransferase BA202_24025 ENOG4108ZB6 transcriptional regulator AsnC family BA202_24030 ENOG4105C5I Dehydrogenase BA202_24035 ENOG4108MUZ hydrolase BA202_24045 ENOG4105C87 Aminotransferase class I and II BA202_24060 ENOG4105Y38 Kinase-associated protein B BA202_24070 ENOG4107R3E Citrate transporter BA202_24085 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BA202_24090 ENOG4105KA0 thioesterase Superfamily protein BA202_24105 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA202_24125 ENOG41069ER domain protein BA202_24140 ENOG4105CEP NADH dehydrogenase BA202_24165 ENOG4105EWC Purine nucleoside phosphorylase BA202_24175 ENOG4108VQJ O-methyltransferase BA202_24190 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BA202_24215 ENOG4108JJA ABC, transporter BA202_24220 ENOG4105C4B ABC transporter, permease BA202_24225 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BA202_24265 ENOG41083MR nifu domain-containing protein BA202_24280 ENOG4108W5N phosphatidylglycerophosphatase a BA202_24300 ENOG4105DAX Pfam:DUF2983 BA202_24315 ENOG4105DYS nad(p)h dehydrogenase (quinone) BA202_24320 ENOG4105D4U had-superfamily hydrolase, subfamily iia BA202_24335 ENOG4105CBT Fructose-1,6-bisphosphatase BA202_24355 ENOG4105MMD transcriptional regulator BA202_24360 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BA202_24365 ENOG4107TXC Transcriptional regulator BA202_24370 ENOG41090T1 Membrane BA202_24395 ENOG4105FAA peptidase M23 BA202_24405 ENOG4105KZD Domain of unknown function (DUF1805) BA202_24410 ENOG4107R8B 5'-nucleotidase BA202_24425 ENOG4105DIW FeS assembly protein SUFB BA202_24430 ENOG4108UNV SUF system FeS assembly protein, NifU family BA202_24435 ENOG4105C9B Cysteine desulfurase BA202_24440 ENOG4105JRK feS assembly protein SufD BA202_24445 ENOG4105C3K feS assembly ATPase SufC BA202_24450 ENOG4105D01 (LipO)protein BA202_24455 ENOG4105D01 (LipO)protein BA202_24460 ENOG4108UMI ABC transporter, permease BA202_24490 ENOG41080E8 Transcriptional regulator, Spx MgsR family BA202_24555 ENOG4108W8B Beta-lactamase domain protein BA202_24560 ENOG4105C1G acyl-Coa dehydrogenase BA202_24565 ENOG4105CHU acetyl-coa acetyltransferase BA202_24580 ENOG4105DZ1 carboxypeptidase BA202_24600 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BA202_24615 ENOG4108SUT Major Facilitator Superfamily BA202_24620 ENOG4107R7I amino acid BA202_24630 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BA202_24640 ENOG4107AYK membrAne BA202_24650 ENOG4105BZU Histidine kinase BA202_24655 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BA202_24660 ENOG4108TU7 Inherit from COG: (ABC) transporter BA202_24670 ENOG4105CJ1 ABC, transporter BA202_24695 ENOG4107ZTW SNARE associated Golgi BA202_24705 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BA202_24710 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_24715 ENOG4105BZU Histidine kinase BA202_24740 ENOG4105C8Q Methyl-accepting chemotaxis BA202_24745 ENOG4105C8Q Methyl-accepting chemotaxis BA202_24750 ENOG4105VG1 fes assembly suf system protein BA202_24755 ENOG4105D4Y metalloprotease BA202_24775 ENOG4107S91 Sodium hydrogen exchanger BA202_24780 ENOG4105NCW Trka-c domain protein BA202_24795 ENOG4108RMU ferritin dps family protein BA202_24810 ENOG4108URH decarboxylase BA202_24830 ENOG4105D9N nucleoside BA202_24835 ENOG4105D9N nucleoside BA202_24850 ENOG4108RYK Nad-dependent epimerase dehydratase BA202_24865 ENOG4105CV8 reductase BA202_24870 ENOG4105F27 Major Facilitator BA202_24875 ENOG4105KVH Transcriptional regulator BA202_24895 ENOG4105D4A Cell wall formation (By similarity) BA202_24905 ENOG4105C8Q Methyl-accepting chemotaxis BA202_24935 ENOG4108MK9 spermidine N(1)-acetyltransferase BA202_24955 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BA202_24965 ENOG4108IPW abc transporter atp-binding protein BA202_24970 ENOG4105CM4 permease protein BA202_25060 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BA202_25070 ENOG4105XZU Preprotein translocase, subunit SecG BA202_25075 ENOG41067MG lrgb family BA202_25125 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_25155 ENOG41090VF Stage v sporulation protein ac BA202_25160 ENOG4105CZ3 stage V sporulation protein ad BA202_25175 ENOG4108QY0 Membrane BA202_25180 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BA202_25185 ENOG4105KRI phosphocarrier protein (HPr BA202_25195 ENOG4105CHW UPF0052 protein BA202_25205 ENOG4108Z4K mutator MutT protein BA202_25215 ENOG4105C3M thioredoxin reductase BA202_25225 ENOG4108S4C acetyltransferase BA202_25245 ENOG41086DT Membrane protein of unknown function BA202_25260 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BA202_25290 ENOG4107TXC Transcriptional regulator BA202_25320 ENOG4105DUM transcriptional regulator, lysR family BA202_25330 ENOG4108WS4 fmn reductase BA202_25345 ENOG4105BZ1 (ABC) transporter BA202_25355 ENOG4105CN1 protease BA202_25360 ENOG4105CRP Part of the ABC transporter FtsEX involved in BA202_25365 ENOG4105CAK Cell division ATP-binding protein ftsE BA202_25375 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BA202_25390 ENOG4108RDQ ABC transporter BA202_25420 ENOG4105MS2 ribosomal subunit Interface protein BA202_25425 ENOG4105VEQ Cold shock protein BA202_25430 ENOG41081UC Inherit from COG: Competence protein BA202_25445 ENOG4105KVH Transcriptional regulator BA202_25460 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BA202_25465 ENOG4108KGH TRANSCRIPTIONal BA202_25470 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BA202_25475 ENOG4105C6Y Udp-glucose 6-dehydrogenase BA202_25480 ENOG4105ESV Glycosyl transferase, family 4 BA202_25490 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BA202_25510 ENOG4105F8D glycoside hydrolase family 4 BA202_25515 ENOG4105VCP PTS System BA202_25520 ENOG4105CK1 PTS System BA202_25540 ENOG4105VCP PTS System BA202_25550 ENOG4105VZJ PTS System BA202_25565 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BA202_25585 ENOG4105ECB domain protein BA202_25590 ENOG4107RSM transcriptional regulator BA202_25625 ENOG4105DAA L-lactate BA202_25635 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BA202_25645 ENOG4105E0M Sulfatase BA202_25670 ENOG4107R8N Glycosyl transferase, family 2 BA202_25680 ENOG4105C94 Transporter BA202_25685 ENOG41069ER domain protein BA202_25710 ENOG4105KBK Zinc finger, swim domain protein BA202_25715 ENOG4105C0D helicase BA202_25745 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BA202_25760 ENOG4107RBB ABC transporter, permease BA202_25765 ENOG4105C19 ABC transporter BA202_25775 ENOG4105CXY transporter BA202_25790 ENOG41065SU Two-component system sensor kinase BA202_25795 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_25805 ENOG4105CMR udp-glucose 4-epimerase BA202_25815 ENOG4108KGH TRANSCRIPTIONal BA202_25820 ENOG4105DG6 mannose-6-phosphate isomerase BA202_25825 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BA202_25835 ENOG4108TJN glycosyl transferase group 1 BA202_25850 ENOG4105ER6 polysaccharide biosynthesis protein BA202_25860 ENOG4105D3Q Sugar transferase BA202_25865 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BA202_25870 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BA202_25875 ENOG4107YJ4 chain length determinant protein BA202_25880 ENOG4105HTX biosynthesis protein BA202_25885 ENOG4107YJ4 chain length determinant protein BA202_25900 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BA202_25910 ENOG4105FRN stage II sporulation protein BA202_25925 ENOG4105DY9 regulatoR BA202_25945 ENOG4106778 Protein of unknown function (DUF1146) BA202_25950 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BA202_25955 ENOG4105C8S subunit m BA202_25960 ENOG4105D65 subunit l BA202_25990 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BA202_26005 ENOG4105BZU Histidine kinase BA202_26055 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BA202_26060 ENOG41062M3 atp synthase BA202_26090 ENOG4108YZG isomerase BA202_26105 ENOG4108VGI doxx family BA202_26110 ENOG4107XC4 flavin reductase domain protein, FMN-binding BA202_26130 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BA202_26140 ENOG4108ZXQ stage ii sporulation protein r BA202_26145 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BA202_26150 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BA202_26165 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BA202_26170 ENOG4105CBT Fructose-1,6-bisphosphatase BA202_26175 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BA202_26195 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BA202_26215 ENOG4105C1G acyl-Coa dehydrogenase BA202_26220 ENOG4105C1G acyl-Coa dehydrogenase BA202_26225 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BA202_26235 ENOG4105DF6 Fe-S oxidoreductase BA202_26250 ENOG4105BZU Histidine kinase BA202_26270 ENOG4105BZU Histidine kinase BA202_26275 ENOG4105KCT ABC transporter BA202_26280 ENOG4108M15 ABC transporter BA202_26285 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BA202_26295 ENOG4105IIU Aminopeptidase BA202_26315 ENOG4105JVQ RNA Polymerase BA202_26325 ENOG410684U Domain of unknown function (DUF1934) BA202_26345 ENOG4105CYW agmatinase BA202_26355 ENOG4105DXB Major Facilitator superfamily BA202_26360 ENOG4107SWG transcriptional regulator MERR family BA202_26365 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BA202_26370 ENOG4105BZ4 penicillin-binding protein BA202_26375 ENOG4108XFG YwhD family BA202_26380 ENOG4108Z4T Peptidase M50 BA202_26385 ENOG41069HH 4-oxalocrotonate tautomerase BA202_26390 ENOG4105DCI Phosphohydrolase BA202_26395 ENOG4108MES Periplasmic binding protein BA202_26400 ENOG4105E0A ABC, transporter BA202_26405 ENOG4105EHG Permease protein BA202_26415 ENOG4108VCI transcription factor, rsfa family BA202_26425 ENOG4108IJ2 phosphate acetyltransferase BA202_26440 ENOG4108VKI Cell wall hydrolase BA202_26460 ENOG4105NCW Trka-c domain protein BA202_26470 ENOG410667J hydrolase BA202_26475 ENOG4105VCH membrane BA202_26485 ENOG4108TU7 Inherit from COG: (ABC) transporter BA202_26490 ENOG4105CJ1 ABC, transporter BA202_26495 ENOG41090WU lipolytic protein G-D-S-L family BA202_26510 ENOG4105D6E homoserine dehydrogenase BA202_26530 ENOG4108Y4K DNA-binding transcriptional activator BA202_26540 ENOG4105WH1 Two component transcriptional regulator luxr family BA202_26545 ENOG4105BZU Histidine kinase BA202_26550 ENOG4105DWF phosphomethylpyrimidine kinase BA202_26555 ENOG4105BZU Histidine kinase BA202_26560 ENOG4105VCD cytoplasmic protein BA202_26565 ENOG4105D22 carbon starvation protein BA202_26570 ENOG4105DY9 regulatoR BA202_26575 ENOG41079KZ Major Facilitator Superfamily BA202_26585 ENOG4105CG5 Glycosyl transferase (Group 1 BA202_26595 ENOG4105EN6 Membrane BA202_26600 ENOG4106YBV Methyl-accepting chemotaxis BA202_26610 ENOG4108S4H thioesterase Superfamily protein BA202_26615 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BA202_26625 ENOG4105K64 Glycosyl transferase, family 2 BA202_26640 ENOG4105C5H ABC transporter BA202_26655 ENOG4105CKK Glycosyl transferase, family 2 BA202_26660 ENOG41067SE Tetr family transcriptional regulator BA202_26670 ENOG4105E0X reductase BA202_26675 ENOG4106F5Q Membrane BA202_26690 ENOG4105DY9 regulatoR BA202_26695 ENOG4108HRK Histidine kinase BA202_26700 ENOG4107RGD Major Facilitator superfamily BA202_26715 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BA202_26725 ENOG4105IW1 AmiS UreI transporter BA202_26760 ENOG4105CMR udp-glucose 4-epimerase BA202_26765 ENOG4108UT2 hemolysin iii BA202_26775 ENOG4105C1J atp-dependent rna helicase BA202_26785 ENOG4105DPN Oligoendopeptidase f BA202_26805 ENOG4105C0H protease BA202_26810 ENOG4105Q2H domain protein BA202_26825 ENOG4105BZU Histidine kinase BA202_26830 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_26860 ENOG4105CDU Replicative dna helicase BA202_26870 ENOG4105BZR domain protein BA202_26875 ENOG4108XMW Membrane BA202_26885 ENOG4108UUM single-stranded DNA-binding protein BA202_26895 ENOG4105C3G gtp-binding protein BA202_26900 ENOG4105VDK protein, conserved in bacteria BA202_26905 ENOG4105D8X mechanosensitive ion channel BA202_26910 ENOG4108ZDA Sporulation protein YyaC BA202_26915 ENOG4105FA0 parb-like partition protein BA202_26920 ENOG4107QJE Chromosome Partitioning Protein BA202_26950 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BA202_26990 ENOG4105CHH sulfate transporter BA202_27005 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BA202_27020 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA202_27045 ENOG4108IBT Inherit from COG: transposase BA202_27070 ENOG4108ZHR arsR family transcriptional regulator BA202_27080 ENOG4105C0R drug resistance transporter emrb qaca subfamily BA202_27085 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BA202_27100 ENOG41086D8 Transcriptional regulator BA202_27105 ENOG41090MY MarR family Transcriptional regulator BA202_27150 ENOG4108NHD germination protein BA202_27165 ENOG4108W2Y isochorismatase BA202_27175 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BA202_27180 ENOG4105BZU Histidine kinase BA202_27205 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BA202_27275 ENOG4105C79 DNA protecting protein DprA BA202_27320 ENOG4105EKQ RNA-directed DNA polymerase BA202_27340 ENOG4105EKQ RNA-directed DNA polymerase BA202_27470 ENOG4105EKQ RNA-directed DNA polymerase BA202_27525 ENOG4107QZI cell division protein FtsK BA202_27555 ENOG4105D7V transposase BA202_27595 ENOG4105DQ6 Transposase BA202_27600 ENOG4105IYK transposase BA202_27645 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA202_27660 ENOG41090VF Stage v sporulation protein ac BA202_27665 ENOG4105CZ3 stage V sporulation protein ad BA202_27680 ENOG4108QY0 Membrane BA202_27685 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BA202_27700 ENOG4108B31 Spore germination protein BA202_27705 ENOG4105E1K spore germination protein BA202_27720 ENOG4105KVH Transcriptional regulator BA202_27730 ENOG4105C4W S-formylglutathione hydrolase BA202_27740 ENOG4105D9M gamma-glutamylcysteine synthetase BA202_27765 ENOG4105DHF Membrane BA202_27785 ENOG4105D7V transposase BA202_27805 ENOG4105KRN Transcriptional regulator, abrb family BA202_27815 ENOG4108FPN Integrase BA202_27820 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BA202_27830 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BA202_27840 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BA202_27850 ENOG4108U05 Transcriptional regulator BA202_27855 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BA202_27875 ENOG4105DND Transcriptional regulator BA202_27880 ENOG4105CAQ asparagine synthetase BA202_27910 ENOG4105DZR Type I site-specific deoxyribonuclease BA202_27945 ENOG41086D8 Transcriptional regulator BA202_27955 ENOG4105VN1 Heat shock protein