locus-tag	class	description
CSW12_00020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSW12_00025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSW12_00030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSW12_00040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSW12_00055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSW12_00065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSW12_00075	COG0151	Belongs to the GarS family
CSW12_00085	COG0583	DNA-binding transcription factor activity
CSW12_00110	COG0210	DNA helicase
CSW12_00120	COG4851	CamS sex pheromone cAM373 precursor
CSW12_00140	COG1335	isochorismatase
CSW12_00155	COG2011	ABC-type metal ion transport system permease component
CSW12_00160	COG1464	Belongs to the NlpA lipoprotein family
CSW12_00180	COG1396	sequence-specific DNA binding
CSW12_00210	COG1484	DNA-dependent DNA replication
CSW12_00230	COG3617	BRO family, N-terminal domain
CSW12_00250	COG0582	viral genome integration into host DNA
CSW12_00370	COG3547	Transposase (IS116 IS110 IS902 family)
CSW12_00440	COG1597	lipid kinase activity
CSW12_00450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSW12_00460	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_00465	COG2076	Multidrug Resistance protein
CSW12_00475	COG2309	aminopeptidase activity
CSW12_00490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW12_00515	COG4807	Protein conserved in bacteria
CSW12_00545	COG1473	amidohydrolase
CSW12_00560	COG0450	alkyl hydroperoxide reductase
CSW12_00565	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CSW12_00575	COG0235	Class ii aldolase
CSW12_00580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_00585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_00590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_00615	COG0166	Belongs to the GPI family
CSW12_00640	COG5002	protein histidine kinase activity
CSW12_00660	COG3541	Predicted nucleotidyltransferase
CSW12_00665	COG2814	Major facilitator Superfamily
CSW12_00670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_00670	COG0723	plastoquinol--plastocyanin reductase activity
CSW12_00680	COG0765	amino acid transport
CSW12_00685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_00695	COG0840	transmembrane signaling receptor activity
CSW12_00720	COG0549	Belongs to the carbamate kinase family
CSW12_00725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_00740	COG0277	FAD linked oxidase domain protein
CSW12_00745	COG0366	Alpha amylase catalytic
CSW12_00750	COG1263	PTS System
CSW12_00750	COG2190	(PTS) system
CSW12_00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_00785	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSW12_00805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_00810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_00815	COG1116	anion transmembrane transporter activity
CSW12_00820	COG0488	(ABC) transporter
CSW12_00870	COG2270	Major facilitator Superfamily
CSW12_00900	COG2310	stress, protein
CSW12_00905	COG2310	stress, protein
CSW12_00910	COG2310	stress, protein
CSW12_00915	COG0861	Integral membrane protein TerC family
CSW12_00925	COG3853	Toxic anion resistance protein (TelA)
CSW12_00940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSW12_00950	COG1295	ribonuclease BN
CSW12_00960	COG2217	Heavy metal translocating P-type atpase
CSW12_00965	COG0697	spore germination
CSW12_00985	COG0586	Pfam SNARE associated Golgi protein
CSW12_01000	COG3871	stress protein (general stress protein 26)
CSW12_01015	COG0535	radical SAM domain protein
CSW12_01035	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSW12_01040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSW12_01055	COG3829	transcription factor binding
CSW12_01065	COG0833	amino acid
CSW12_01075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_01110	COG1263	PTS System
CSW12_01115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_01130	COG1216	Glycosyl transferase, family 2
CSW12_01140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_01140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSW12_01145	COG0463	Glycosyl transferase, family 2
CSW12_01160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CSW12_01180	COG1228	amidohydrolase
CSW12_01185	COG1090	epimerase
CSW12_01215	COG1988	membrane-bound metal-dependent
CSW12_01220	COG1194	a g-specific adenine glycosylase
CSW12_01245	COG1132	(ABC) transporter
CSW12_01250	COG4129	membrane
CSW12_01255	COG0070	glutamate synthase
CSW12_01255	COG0069	glutamate synthase activity
CSW12_01255	COG0067	glutamate synthase
CSW12_01265	COG4555	ABC transporter
CSW12_01285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSW12_01290	COG0735	belongs to the Fur family
CSW12_01415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSW12_01440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSW12_01445	COG1716	ATPase activity
CSW12_01445	COG5001	Diguanylate cyclase
CSW12_01455	COG2766	serine protein kinase
CSW12_01480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_01490	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSW12_01495	COG2268	Band 7 protein
CSW12_01505	COG3290	protein histidine kinase activity
CSW12_01510	COG4565	transcriptional regulatory protein
CSW12_01515	COG2851	Citrate transporter
CSW12_01540	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSW12_01545	COG3842	ATPase activity
CSW12_01550	COG1175	transmembrane transport
CSW12_01555	COG0395	ABC-type sugar transport system, permease component
CSW12_01565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSW12_01570	COG0745	RESPONSE REGULATOR receiver
CSW12_01575	COG5002	protein histidine kinase activity
CSW12_01585	COG4990	cell redox homeostasis
CSW12_01595	COG3290	protein histidine kinase activity
CSW12_01600	COG4565	transcriptional regulatory protein
CSW12_01605	COG3493	citrate carrier protein
CSW12_01610	COG0281	malic enzyme
CSW12_01620	COG0697	spore germination
CSW12_01625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_01635	COG5002	protein histidine kinase activity
CSW12_01640	COG0745	RESPONSE REGULATOR receiver
CSW12_01655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSW12_01665	COG3383	formate dehydrogenase (NAD+) activity
CSW12_01670	COG2427	Protein of unknown function (DUF1641)
CSW12_01685	COG0531	amino acid
CSW12_01690	COG0640	Transcriptional regulator
CSW12_01695	COG2217	Heavy metal translocating P-type atpase
CSW12_01700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSW12_01715	COG3227	Zinc metalloprotease (Elastase)
CSW12_01735	COG2720	vancomycin resistance protein
CSW12_01740	COG1316	TRANSCRIPTIONal
CSW12_01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_01750	COG0346	lactoylglutathione lyase activity
CSW12_01755	COG1253	flavin adenine dinucleotide binding
CSW12_01760	COG1027	Aspartate ammonia-lyase
CSW12_01765	COG1620	l-lactate permease
CSW12_01780	COG3104	oligopeptide transport
CSW12_01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_01795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_01805	COG2226	methyltransferase
CSW12_01815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_01825	COG4548	von Willebrand factor, type A
CSW12_01830	COG0714	Associated with various cellular activities
CSW12_01850	COG0531	amino acid
CSW12_01855	COG2188	Transcriptional regulator
CSW12_01860	COG1263	PTS System
CSW12_01860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_01865	COG0366	Alpha amylase catalytic
CSW12_01880	COG0697	spore germination
CSW12_01885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSW12_01890	COG1115	amino acid carrier protein
CSW12_01895	COG1126	abc transporter atp-binding protein
CSW12_01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_01905	COG0765	amino acid transport
CSW12_01910	COG0765	amino acid transport
CSW12_01915	COG0833	amino acid
CSW12_01930	COG1595	DNA-templated transcription, initiation
CSW12_01940	COG2378	regulation of single-species biofilm formation
CSW12_01945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CSW12_01950	COG5002	protein histidine kinase activity
CSW12_01965	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_01990	COG0601	transmembrane transport
CSW12_01995	COG4608	Belongs to the ABC transporter superfamily
CSW12_02005	COG2271	Major facilitator Superfamily
CSW12_02010	COG1846	Transcriptional regulator
CSW12_02015	COG0477	Major facilitator Superfamily
CSW12_02020	COG1609	Transcriptional regulator
CSW12_02025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW12_02040	COG4974	Belongs to the 'phage' integrase family
CSW12_02245	COG4824	toxin secretion phage lysis holin
CSW12_02250	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_02250	COG1388	LysM domain
CSW12_02250	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_02295	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_02300	COG1879	ABC-type sugar transport system periplasmic component
CSW12_02305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSW12_02435	COG0582	viral genome integration into host DNA
CSW12_02470	COG0740	serine-type endopeptidase activity
CSW12_02540	COG4824	toxin secretion phage lysis holin
CSW12_02615	COG0840	transmembrane signaling receptor activity
CSW12_02620	COG1388	LysM domain
CSW12_02620	COG3584	3D domain protein
CSW12_02625	COG1476	TRANSCRIPTIONal
CSW12_02645	COG3104	oligopeptide transport
CSW12_02650	COG1114	Component of the transport system for branched-chain amino acids
CSW12_02665	COG1113	amino acid transport
CSW12_02670	COG2252	PERMEase
CSW12_02685	COG2153	protein acetylation
CSW12_02695	COG0569	domain protein
CSW12_02695	COG0475	glutathione-regulated potassium exporter activity
CSW12_02710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSW12_02715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSW12_02720	COG0833	amino acid
CSW12_02725	COG4990	cell redox homeostasis
CSW12_02740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_02745	COG0697	spore germination
CSW12_02750	COG0531	amino acid
CSW12_02765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_02770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_02775	COG1918	ferrous iron import across plasma membrane
CSW12_02775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_02780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW12_02785	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_02790	COG0581	inorganic phosphate transmembrane transporter activity
CSW12_02800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW12_02925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CSW12_02950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSW12_02955	COG1116	anion transmembrane transporter activity
CSW12_02960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_02965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_02970	COG0352	thiamine-phosphate diphosphorylase activity
CSW12_02975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_02980	COG2104	thiamine diphosphate biosynthetic process
CSW12_02990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_02995	COG0351	phosphomethylpyrimidine kinase
CSW12_03040	COG2205	protein histidine kinase activity
CSW12_03045	COG2814	Major facilitator Superfamily
CSW12_03050	COG1846	Transcriptional regulator
CSW12_03065	COG2252	PERMEase
CSW12_03070	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_03130	COG0778	Nitroreductase
CSW12_03135	COG2719	SpoVR family
CSW12_03175	COG1401	restriction endodeoxyribonuclease activity
CSW12_03175	COG1401	restriction endodeoxyribonuclease activity
CSW12_03190	COG1414	Transcriptional regulator
CSW12_03210	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSW12_03215	COG1937	Protein conserved in bacteria
CSW12_03220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_03220	COG0425	Belongs to the sulfur carrier protein TusA family
CSW12_03225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_03225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_03230	COG0425	Belongs to the sulfur carrier protein TusA family
CSW12_03235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_03245	COG2210	Belongs to the sulfur carrier protein TusA family
CSW12_03250	COG0730	response to heat
CSW12_03260	COG1316	TRANSCRIPTIONal
CSW12_03265	COG0604	alcohol dehydrogenase
CSW12_03270	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSW12_03290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_03290	COG3711	transcriptional antiterminator
CSW12_03295	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_03300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_03320	COG1388	LysM domain
CSW12_03320	COG3584	3D domain protein
CSW12_03325	COG0577	efflux transmembrane transporter activity
CSW12_03330	COG1136	(ABC) transporter
CSW12_03340	COG5522	Integral membrane protein (intg_mem_TP0381)
CSW12_03355	COG0577	efflux transmembrane transporter activity
CSW12_03360	COG1114	Component of the transport system for branched-chain amino acids
CSW12_03365	COG3546	catalase activity
CSW12_03400	COG0586	Pfam SNARE associated Golgi protein
CSW12_03435	COG0531	amino acid
CSW12_03440	COG0475	glutathione-regulated potassium exporter activity
CSW12_03450	COG1737	Transcriptional regulator
CSW12_03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_03460	COG1263	PTS System
CSW12_03470	COG2259	Doxx family
CSW12_03490	COG1522	sequence-specific DNA binding
CSW12_03495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSW12_03495	COG0165	Argininosuccinate lyase
CSW12_03500	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_03510	COG2076	Multidrug Resistance protein
CSW12_03520	COG1309	transcriptional regulator
CSW12_03525	COG2814	Major facilitator Superfamily
CSW12_03530	COG1733	regulation of RNA biosynthetic process
CSW12_03550	COG0693	protein deglycase activity
CSW12_03555	COG0753	catalase activity
CSW12_03555	COG0693	protein deglycase activity
CSW12_03565	COG0531	amino acid
CSW12_03580	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_03600	COG1132	(ABC) transporter
CSW12_03605	COG1132	(ABC) transporter
CSW12_03615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_03620	COG0765	amino acid transport
CSW12_03625	COG1126	abc transporter atp-binding protein
CSW12_03640	COG0189	ligase activity
CSW12_03660	COG4585	Histidine kinase
CSW12_03665	COG2197	response regulator
CSW12_03685	COG0028	Belongs to the TPP enzyme family
CSW12_03690	COG3527	Alpha-acetolactate decarboxylase
CSW12_03705	COG0561	phosphatase activity
CSW12_03715	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_03715	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_03720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSW12_03745	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_03750	COG2244	polysaccharide biosynthetic process
CSW12_03780	COG1024	Enoyl-CoA hydratase
CSW12_03840	COG0601	transmembrane transport
CSW12_03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_03850	COG0444	Belongs to the ABC transporter superfamily
CSW12_03855	COG4608	Belongs to the ABC transporter superfamily
CSW12_03865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_03900	COG0477	Major facilitator Superfamily
CSW12_03905	COG3290	protein histidine kinase activity
CSW12_03910	COG4565	transcriptional regulatory protein
CSW12_03915	COG3181	Tripartite tricarboxylate transporter family receptor
CSW12_03920	COG0494	nUDIX hydrolase
CSW12_03925	COG0513	Belongs to the DEAD box helicase family
CSW12_03935	COG1061	Type III restriction enzyme res subunit
CSW12_03950	COG4978	Transcriptional regulator
CSW12_03950	COG0789	Transcriptional regulator
CSW12_03970	COG0305	Participates in initiation and elongation during chromosome replication
CSW12_04005	COG0477	Major facilitator Superfamily
CSW12_04060	COG1073	alpha beta
CSW12_04110	COG1183	phosphatidylcholine synthase activity
CSW12_04125	COG2814	Major facilitator Superfamily
CSW12_04130	COG0640	Transcriptional regulator
CSW12_04145	COG2376	Dihydroxyacetone kinase
CSW12_04175	COG2376	Dihydroxyacetone kinase
CSW12_04220	COG0457	Tetratricopeptide repeat
CSW12_04230	COG2373	Large extracellular alpha-helical protein
CSW12_04275	COG3237	CsbD-like
CSW12_04310	COG1191	sigma factor activity
CSW12_04320	COG2208	phosphoserine phosphatase activity
CSW12_04330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW12_04335	COG2205	protein histidine kinase activity
CSW12_04335	COG5002	protein histidine kinase activity
CSW12_04335	COG0784	Response regulator, receiver
CSW12_04380	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CSW12_04400	COG0420	3'-5' exonuclease activity
CSW12_04405	COG4717	serine-type aminopeptidase activity
CSW12_04420	COG1280	lysine exporter protein (LysE YggA)
CSW12_04425	COG0346	lactoylglutathione lyase activity
CSW12_04430	COG0346	lactoylglutathione lyase activity
CSW12_04435	COG0457	Tetratricopeptide repeat
CSW12_04445	COG2267	carboxylic ester hydrolase activity
CSW12_04465	COG2140	Oxalate decarboxylase
CSW12_04470	COG3620	sequence-specific DNA binding
CSW12_04475	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSW12_04480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSW12_04490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSW12_04515	COG3973	AAA domain
CSW12_04550	COG4980	gas vesicle protein
CSW12_04555	COG0537	adenosine 5'-monophosphoramidase activity
CSW12_04565	COG1131	(ABC) transporter
CSW12_04570	COG4473	ABC transporter
CSW12_04585	COG1309	transcriptional regulator
CSW12_04595	COG3402	PFAM membrane-flanked domain
CSW12_04600	COG3428	Bacterial PH domain
CSW12_04660	COG0697	spore germination
CSW12_04665	COG3402	PFAM membrane-flanked domain
CSW12_04670	COG3428	Bacterial PH domain
CSW12_04675	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_04680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_04735	COG1309	transcriptional regulator
CSW12_04740	COG1511	domain protein
CSW12_04765	COG1609	Transcriptional regulator
CSW12_04775	COG1234	tRNA 3'-trailer cleavage
CSW12_04780	COG0095	Lipoate-protein ligase
CSW12_04790	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_04800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSW12_04810	COG4208	sulfate ABC transporter
CSW12_04830	COG1408	metallophosphoesterase
CSW12_04845	COG1078	dGTPase activity
CSW12_04855	COG1595	DNA-templated transcription, initiation
CSW12_04860	COG2207	Transcriptional regulator
CSW12_04860	COG3708	Transcriptional regulator
CSW12_04875	COG2205	protein histidine kinase activity
CSW12_04880	COG0745	RESPONSE REGULATOR receiver
CSW12_04900	COG0501	Belongs to the peptidase M48B family
CSW12_04905	COG0840	transmembrane signaling receptor activity
CSW12_04915	COG3693	PFAM glycoside hydrolase, family 10
CSW12_04925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSW12_04935	COG2224	Isocitrate lyase
CSW12_04950	COG1278	Cold shock
CSW12_04965	COG4903	ComK protein
CSW12_04975	COG0398	Pfam SNARE associated Golgi protein
CSW12_05035	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSW12_05060	COG0367	asparagine synthase
CSW12_05075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSW12_05270	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_05285	COG0367	asparagine synthase
CSW12_05300	COG0753	catalase activity
CSW12_05305	COG0004	ammonium transporteR
CSW12_05335	COG2996	Protein conserved in bacteria
CSW12_05370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_05385	COG0561	phosphatase activity
CSW12_05410	COG2267	carboxylic ester hydrolase activity
CSW12_05425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_05430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSW12_05435	COG5504	Zn-dependent protease
CSW12_05450	COG0180	Tryptophanyl-tRNA synthetase
CSW12_05465	COG4166	transmembrane transport
CSW12_05470	COG0601	transmembrane transport
CSW12_05475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_05480	COG0444	Belongs to the ABC transporter superfamily
CSW12_05485	COG4608	Belongs to the ABC transporter superfamily
CSW12_05490	COG0534	Mate efflux family protein
CSW12_05495	COG4166	transmembrane transport
CSW12_05510	COG1393	Belongs to the ArsC family
CSW12_05515	COG0861	Integral membrane protein TerC family
CSW12_05525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_05535	COG1164	Oligoendopeptidase f
CSW12_05550	COG2346	COG2346, Truncated hemoglobins
CSW12_05555	COG4116	CYTH
CSW12_05565	COG2357	RelA SpoT domain protein
CSW12_05575	COG0564	pseudouridine synthase activity
CSW12_05590	COG0772	Belongs to the SEDS family
CSW12_05595	COG1216	Glycosyl transferase, family 2
CSW12_05615	COG0457	Tetratricopeptide repeat
CSW12_05615	COG0463	Glycosyl transferase, family 2
CSW12_05635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CSW12_05650	COG1091	dTDP-4-dehydrorhamnose reductase activity
CSW12_05695	COG2153	protein acetylation
CSW12_05705	COG2382	esterase
CSW12_05730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSW12_05745	COG0512	Glutamine amidotransferase of anthranilate synthase
CSW12_05780	COG1620	l-lactate permease
CSW12_05795	COG5634	Uncharacterized conserved protein (DUF2278)
CSW12_05840	COG2226	methyltransferase
CSW12_05860	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_05870	COG1476	TRANSCRIPTIONal
CSW12_05915	COG4152	abc transporter atp-binding protein
CSW12_05920	COG1668	transmembrane transport
CSW12_05950	COG1686	Belongs to the peptidase S11 family
CSW12_05955	COG0681	Belongs to the peptidase S26 family
CSW12_05990	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_06000	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSW12_06005	COG1177	transmembrane transport
CSW12_06010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSW12_06020	COG2409	Drug exporters of the RND superfamily
CSW12_06030	COG0564	pseudouridine synthase activity
CSW12_06040	COG2340	Cysteine-rich secretory protein family
CSW12_06045	COG0247	lactate metabolic process
CSW12_06050	COG0277	FAD linked oxidase domain protein
CSW12_06055	COG3835	regulator
CSW12_06065	COG0745	RESPONSE REGULATOR receiver
CSW12_06070	COG5002	protein histidine kinase activity
CSW12_06075	COG2186	Transcriptional regulator
CSW12_06095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSW12_06105	COG2116	formate transmembrane transporter activity
CSW12_06110	COG0861	Integral membrane protein TerC family
CSW12_06115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_06125	COG2030	dehydratase
CSW12_06145	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_06150	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSW12_06160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_06180	COG1840	ABC-type Fe3 transport system, periplasmic component
CSW12_06185	COG3842	ATPase activity
CSW12_06210	COG1349	DNA-binding transcription factor activity
CSW12_06225	COG0235	Class ii aldolase
CSW12_06235	COG2861	carbohydrate metabolic process
CSW12_06245	COG3852	Histidine kinase
CSW12_06250	COG1846	Transcriptional regulator
CSW12_06260	COG2318	DinB family
CSW12_06270	COG5002	protein histidine kinase activity
CSW12_06280	COG0720	synthase
CSW12_06295	COG4873	Protein conserved in bacteria
CSW12_06330	COG1780	Probably involved in ribonucleotide reductase function
CSW12_06335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW12_06350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW12_06355	COG1725	Transcriptional regulator
CSW12_06360	COG1131	(ABC) transporter
CSW12_06370	COG1131	(ABC) transporter
CSW12_06390	COG1522	sequence-specific DNA binding
CSW12_06400	COG1335	isochorismatase
CSW12_06410	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_06415	COG2070	2-Nitropropane dioxygenase
CSW12_06420	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSW12_06430	COG1696	Membrane protein involved in D-alanine export
CSW12_06455	COG0716	FMN binding
CSW12_06530	COG1846	Transcriptional regulator
CSW12_06540	COG1301	dicarboxylic acid transport
CSW12_06545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_06550	COG4709	membrane
CSW12_06555	COG3874	Sporulation protein YtfJ
CSW12_06585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_06590	COG0028	Belongs to the TPP enzyme family
CSW12_06595	COG0440	acetolactate synthase activity
CSW12_06670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSW12_06685	COG1183	phosphatidylcholine synthase activity
CSW12_06690	COG1368	sulfuric ester hydrolase activity
CSW12_06700	COG0019	diaminopimelate decarboxylase activity
CSW12_06720	COG0529	Catalyzes the synthesis of activated sulfate
CSW12_06725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSW12_06745	COG1648	precorrin-2 dehydrogenase activity
CSW12_06760	COG0733	neurotransmitter:sodium symporter activity
CSW12_06780	COG1757	Na H antiporter
CSW12_06795	COG4758	membrane
CSW12_06800	COG4585	Histidine kinase
CSW12_06805	COG2197	response regulator
CSW12_06810	COG3316	Transposase and inactivated derivatives
CSW12_06820	COG1114	Component of the transport system for branched-chain amino acids
CSW12_06875	COG0730	response to heat
CSW12_06880	COG0306	phosphate transporter
CSW12_06885	COG1392	Phosphate transport regulator
CSW12_06890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_06905	COG3852	Histidine kinase
CSW12_06910	COG1801	Protein of unknown function DUF72
CSW12_06920	COG0582	viral genome integration into host DNA
CSW12_06925	COG5002	protein histidine kinase activity
CSW12_06940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CSW12_06940	COG0392	lysyltransferase activity
CSW12_06955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSW12_06960	COG1686	Belongs to the peptidase S11 family
CSW12_06965	COG2715	membrane protein required for spore maturation
CSW12_06970	COG0700	Nucleoside recognition
CSW12_06975	COG1187	pseudouridine synthase activity
CSW12_06985	COG1333	cytochrome c biogenesis protein
CSW12_06990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW12_06995	COG0745	RESPONSE REGULATOR receiver
CSW12_07000	COG5002	protein histidine kinase activity
CSW12_07005	COG2096	Adenosyltransferase
CSW12_07020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CSW12_07030	COG1141	Ferredoxin
CSW12_07040	COG0514	ATP-dependent DNA helicase (RecQ)
CSW12_07045	COG1266	CAAX protease self-immunity
CSW12_07055	COG1408	metallophosphoesterase
CSW12_07060	COG0789	Transcriptional regulator
CSW12_07070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSW12_07090	COG0492	ferredoxin-NADP+ reductase activity
CSW12_07095	COG0252	asparaginase activity
CSW12_07170	COG1609	Transcriptional regulator
CSW12_07175	COG2056	Na+-H+ antiporter family
CSW12_07180	COG0596	Alpha beta hydrolase
CSW12_07190	COG0737	Belongs to the 5'-nucleotidase family
CSW12_07190	COG1525	nuclease
CSW12_07190	COG4085	toxin activity
CSW12_07205	COG0456	acetyltransferase
CSW12_07205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW12_07210	COG0656	L-ascorbic acid biosynthetic process
CSW12_07215	COG0667	Aldo Keto reductase
CSW12_07235	COG1300	Membrane
CSW12_07240	COG0735	belongs to the Fur family
CSW12_07250	COG4974	Belongs to the 'phage' integrase family
CSW12_07275	COG0598	Magnesium transport protein CorA
CSW12_07290	COG1846	Transcriptional regulator
CSW12_07305	COG1131	(ABC) transporter
CSW12_07310	COG1725	Transcriptional regulator
CSW12_07320	COG1686	Belongs to the peptidase S11 family
CSW12_07340	COG0733	neurotransmitter:sodium symporter activity
CSW12_07365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_07380	COG0697	spore germination
CSW12_07385	COG0561	phosphatase activity
CSW12_07390	COG4086	secreted protein
CSW12_07395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSW12_07400	COG0456	acetyltransferase
CSW12_07405	COG1547	Domain of unknown function (DUF309)
CSW12_07435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSW12_07455	COG3711	transcriptional antiterminator
CSW12_07460	COG2190	(PTS) system
CSW12_07460	COG1263	PTS System
CSW12_07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_07485	COG0778	Nitroreductase
CSW12_07490	COG2203	Gaf domain
CSW12_07490	COG2199	diguanylate cyclase activity
CSW12_07500	COG2084	Dehydrogenase
CSW12_07535	COG0436	Aminotransferase
CSW12_07540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSW12_07560	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_07565	COG1695	Transcriptional regulator
CSW12_07600	COG0183	Belongs to the thiolase family
CSW12_07615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_07675	COG3842	ATPase activity
CSW12_07680	COG0366	Alpha amylase catalytic
CSW12_07690	COG2182	Extracellular solute-binding protein
CSW12_07695	COG1175	transmembrane transport
CSW12_07700	COG3833	ABC-type maltose transport systems, permease component
CSW12_07705	COG1609	Transcriptional regulator
CSW12_07710	COG0436	Aminotransferase
CSW12_07720	COG2205	protein histidine kinase activity
CSW12_07735	COG3209	COG3209 Rhs family protein
CSW12_07755	COG2814	Major facilitator Superfamily
CSW12_07800	COG1408	metallophosphoesterase
CSW12_07805	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_07810	COG2200	EAL domain
CSW12_07825	COG4703	Protein of unknown function (DUF1797)
CSW12_07835	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CSW12_07845	COG0517	IMP dehydrogenase activity
CSW12_07850	COG0583	DNA-binding transcription factor activity
CSW12_07870	COG0569	domain protein
CSW12_07875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSW12_07890	COG0561	phosphatase activity
CSW12_07905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_07910	COG0022	dehydrogenase e1 component
CSW12_07960	COG1982	Orn Lys Arg decarboxylase major
CSW12_07980	COG0483	inositol monophosphate 1-phosphatase activity
CSW12_08005	COG4896	Protein conserved in bacteria
CSW12_08015	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CSW12_08020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSW12_08030	COG0772	Belongs to the SEDS family
CSW12_08040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CSW12_08075	COG3336	cytochrome c oxidase
CSW12_08090	COG2340	Cysteine-rich secretory protein family
CSW12_08105	COG0406	alpha-ribazole phosphatase activity
CSW12_08110	COG3679	Belongs to the UPF0342 family
CSW12_08125	COG0742	ribosomal rna small subunit methyltransferase
CSW12_08135	COG3314	Sporulation integral membrane protein YlbJ
CSW12_08140	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSW12_08145	COG3480	Lon protease (S16) C-terminal proteolytic domain
CSW12_08155	COG1399	metal-binding, possibly nucleic acid-binding protein
CSW12_08180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSW12_08205	COG0768	penicillin binding
CSW12_08225	COG0772	Belongs to the SEDS family
CSW12_08230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CSW12_08245	COG0849	cell division
CSW12_08250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSW12_08260	COG1191	sigma factor activity
CSW12_08265	COG1191	sigma factor activity
CSW12_08270	COG1873	PFAM PRC-barrel domain
CSW12_08280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSW12_08290	COG0762	integral membrane protein
CSW12_08295	COG2302	S4 RNA-binding domain
CSW12_08300	COG3599	regulation of cell shape
CSW12_08320	COG0564	pseudouridine synthase activity
CSW12_08380	COG3069	C4-dicarboxylate transmembrane transporter activity
CSW12_08400	COG0006	proline dipeptidase activity
CSW12_08425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSW12_08430	COG1561	YicC-like family, N-terminal region
CSW12_08450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSW12_08455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSW12_08470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSW12_08470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSW12_08480	COG0631	protein serine/threonine phosphatase activity
CSW12_08485	COG2815	serine threonine protein kinase
CSW12_08485	COG0515	serine threonine protein kinase
CSW12_08495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSW12_08500	COG1564	THIamine pyrophosphokinase
CSW12_08515	COG1302	Protein conserved in bacteria
CSW12_08520	COG1461	Dihydroxyacetone kinase
CSW12_08525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSW12_08540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSW12_08545	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_08560	COG1196	nuclear chromosome segregation
CSW12_08565	COG0552	protein localization to endoplasmic reticulum
CSW12_08575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSW12_08585	COG1837	Belongs to the UPF0109 family
CSW12_08625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSW12_08630	COG0758	DNA mediated transformation
CSW12_08635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW12_08645	COG4974	Belongs to the 'phage' integrase family
CSW12_08690	COG4589	Belongs to the CDS family
CSW12_08700	COG0750	zinc metalloprotease
CSW12_08720	COG0195	Participates in both transcription termination and antitermination
CSW12_08725	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CSW12_08730	COG1358	cellular component organization or biogenesis
CSW12_08740	COG1550	Protein conserved in bacteria
CSW12_08755	COG0196	riboflavin kinase activity
CSW12_08770	COG0726	polysaccharide deacetylase
CSW12_08775	COG0612	Peptidase, M16
CSW12_08780	COG1873	PFAM PRC-barrel domain
CSW12_08785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_08790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSW12_08795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW12_08800	COG0527	aspartate kinase activity
CSW12_08810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSW12_08815	COG0740	serine-type endopeptidase activity
CSW12_08835	COG2188	Transcriptional regulator
CSW12_08860	COG0612	Peptidase, M16
CSW12_08865	COG0612	Peptidase, M16
CSW12_08870	COG0300	oxidoreductase activity
CSW12_08885	COG1426	Protein conserved in bacteria
CSW12_08890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSW12_08915	COG1692	metallophosphoesterase
CSW12_08920	COG2359	stage V sporulation protein S
CSW12_08930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSW12_08930	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSW12_08935	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSW12_08945	COG4550	Control of competence regulator ComK, YlbF/YmcA
CSW12_08970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_08975	COG1368	sulfuric ester hydrolase activity
CSW12_08990	COG3773	Cell wall hydrolase
CSW12_08995	COG1404	Belongs to the peptidase S8 family
CSW12_09005	COG2723	6-phospho-beta-galactosidase activity
CSW12_09010	COG2188	Transcriptional regulator
CSW12_09020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_09030	COG1346	cytolysis
CSW12_09050	COG1086	Polysaccharide biosynthesis protein
CSW12_09070	COG3300	MHYT domain
CSW12_09070	COG5001	Diguanylate cyclase
CSW12_09075	COG2267	carboxylic ester hydrolase activity
CSW12_09090	COG2364	Membrane
CSW12_09100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSW12_09105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSW12_09110	COG2169	Transcriptional regulator
CSW12_09115	COG0708	Exodeoxyribonuclease III
CSW12_09120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_09125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_09130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_09135	COG1120	ATPase activity
CSW12_09140	COG2819	hydrolase of the alpha beta superfamily
CSW12_09150	COG1937	Protein conserved in bacteria
CSW12_09155	COG2608	mercury ion transmembrane transporter activity
CSW12_09160	COG2217	Heavy metal translocating P-type atpase
CSW12_09175	COG2116	formate transmembrane transporter activity
CSW12_09180	COG1408	metallophosphoesterase
CSW12_09200	COG1113	amino acid transport
CSW12_09215	COG2322	membrane
CSW12_09220	COG1979	alcohol dehydrogenase
CSW12_09225	COG1349	DNA-binding transcription factor activity
CSW12_09230	COG1105	Belongs to the carbohydrate kinase PfkB family
CSW12_09235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW12_09235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW12_09235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_09245	COG1388	LysM domain
CSW12_09245	COG3584	3D domain protein
CSW12_09275	COG0464	growth
CSW12_09280	COG2860	membrane
CSW12_09285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSW12_09290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CSW12_09295	COG0789	Transcriptional regulator
CSW12_09300	COG0174	glutamine synthetase
CSW12_09305	COG1695	Transcriptional regulator
CSW12_09325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSW12_09335	COG0737	Belongs to the 5'-nucleotidase family
CSW12_09340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_09375	COG1132	(ABC) transporter
CSW12_09380	COG1132	(ABC) transporter
CSW12_09405	COG0730	response to heat
CSW12_09420	COG1346	cytolysis
CSW12_09430	COG0583	DNA-binding transcription factor activity
CSW12_09445	COG1131	(ABC) transporter
CSW12_09470	COG0785	Cytochrome C biogenesis protein
CSW12_09475	COG4846	Membrane protein involved in cytochrome C biogenesis
CSW12_09505	COG2226	methyltransferase
CSW12_09530	COG0010	Belongs to the arginase family
CSW12_09535	COG1329	Transcriptional regulator
CSW12_09540	COG1902	pentaerythritol trinitrate reductase activity
CSW12_09545	COG0069	glutamate synthase activity
CSW12_09555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_09560	COG0346	lactoylglutathione lyase activity
CSW12_09565	COG0400	carboxylic ester hydrolase activity
CSW12_09570	COG5002	protein histidine kinase activity
CSW12_09585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_09630	COG1396	sequence-specific DNA binding
CSW12_09635	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_09640	COG1268	BioY protein
CSW12_09645	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_09650	COG0183	Belongs to the thiolase family
CSW12_09665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSW12_09675	COG2211	Major facilitator Superfamily
CSW12_09695	COG0726	polysaccharide deacetylase
CSW12_09705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSW12_09710	COG2274	protein secretion by the type I secretion system
CSW12_09720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_09745	COG0824	Thioesterase
CSW12_09750	COG4841	protein insertion into membrane
CSW12_09770	COG0745	RESPONSE REGULATOR receiver
CSW12_09775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_09780	COG1832	CoA-binding protein
CSW12_09790	COG0187	DNA topoisomerase II activity
CSW12_09795	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSW12_09800	COG0673	inositol 2-dehydrogenase activity
CSW12_09820	COG1131	(ABC) transporter
CSW12_09830	COG1595	DNA-templated transcription, initiation
CSW12_09840	COG1316	TRANSCRIPTIONal
CSW12_09845	COG4166	transmembrane transport
CSW12_09850	COG4166	transmembrane transport
CSW12_09855	COG4166	transmembrane transport
CSW12_09860	COG2226	methyltransferase
CSW12_09895	COG0531	amino acid
CSW12_09910	COG0697	spore germination
CSW12_09920	COG3383	formate dehydrogenase (NAD+) activity
CSW12_09925	COG2427	Protein of unknown function (DUF1641)
CSW12_09930	COG5609	conserved protein (DUF2294)
CSW12_09935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSW12_09950	COG2116	formate transmembrane transporter activity
CSW12_09955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_09960	COG0303	'Molybdopterin
CSW12_09965	COG0314	molybdopterin synthase activity
CSW12_09975	COG0489	protein tyrosine kinase activity
CSW12_09990	COG3326	Membrane
CSW12_09995	COG2962	Rard protein
CSW12_10000	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CSW12_10005	COG1657	PFAM Prenyltransferase squalene oxidase
CSW12_10015	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_10020	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_10030	COG4145	pantothenate transmembrane transporter activity
CSW12_10045	COG0165	Argininosuccinate lyase
CSW12_10055	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_10085	COG0716	FMN binding
CSW12_10095	COG1278	Cold shock
CSW12_10120	COG2720	vancomycin resistance protein
CSW12_10125	COG2514	catechol 2,3-dioxygenase activity
CSW12_10140	COG1285	pathogenesis
CSW12_10150	COG3852	Histidine kinase
CSW12_10190	COG1876	peptidase activity
CSW12_10205	COG1309	transcriptional regulator
CSW12_10240	COG1404	Belongs to the peptidase S8 family
CSW12_10290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_10300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_10320	COG0697	spore germination
CSW12_10340	COG3397	chitin binding
CSW12_10345	COG0823	Involved in the tonB-independent uptake of proteins
CSW12_10365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_10365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_10380	COG1183	phosphatidylcholine synthase activity
CSW12_10405	COG0277	FAD linked oxidase domain protein
CSW12_10410	COG0385	Bile acid
CSW12_10420	COG0457	Tetratricopeptide repeat
CSW12_10435	COG0604	alcohol dehydrogenase
CSW12_10440	COG0640	Transcriptional regulator
CSW12_10450	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_10475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_10510	COG1164	Oligoendopeptidase f
CSW12_10515	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CSW12_10550	COG0583	DNA-binding transcription factor activity
CSW12_10565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_10590	COG3739	integral membrane protein
CSW12_10595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_10600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_10605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_10620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_10625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSW12_10665	COG2814	Major facilitator Superfamily
CSW12_10670	COG1113	amino acid transport
CSW12_10675	COG0604	alcohol dehydrogenase
CSW12_10710	COG2072	flavoprotein involved in K transport
CSW12_10755	COG1151	hydroxylamine reductase activity
CSW12_10810	COG1280	lysine exporter protein (LysE YggA)
CSW12_10820	COG1191	sigma factor activity
CSW12_10830	COG0726	polysaccharide deacetylase
CSW12_10840	COG1733	regulation of RNA biosynthetic process
CSW12_10845	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_10850	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_10865	COG0367	asparagine synthase
CSW12_10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_10945	COG0673	inositol 2-dehydrogenase activity
CSW12_10950	COG2188	Transcriptional regulator
CSW12_10985	COG0814	amino acid
CSW12_11000	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_11005	COG2824	Alkylphosphonate utilization operon protein PhnA
CSW12_11045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSW12_11050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSW12_11055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSW12_11060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CSW12_11090	COG2706	6-phosphogluconolactonase activity
CSW12_11095	COG3813	Protein conserved in bacteria
CSW12_11100	COG1357	PFAM Pentapeptide repeats (8 copies)
CSW12_11110	COG0697	spore germination
CSW12_11135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_11145	COG0789	Transcriptional regulator
CSW12_11150	COG1253	flavin adenine dinucleotide binding
CSW12_11180	COG0477	Major facilitator Superfamily
CSW12_11190	COG0500	methyltransferase
CSW12_11220	COG0628	permease
CSW12_11230	COG0180	Tryptophanyl-tRNA synthetase
CSW12_11235	COG0110	maltose O-acetyltransferase activity
CSW12_11240	COG0738	Major facilitator superfamily
CSW12_11245	COG1940	carbohydrate kinase activity
CSW12_11250	COG0346	lactoylglutathione lyase activity
CSW12_11285	COG1011	Hydrolase
CSW12_11310	COG1131	(ABC) transporter
CSW12_11320	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_11355	COG0778	Nitroreductase
CSW12_11360	COG1733	regulation of RNA biosynthetic process
CSW12_11380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSW12_11390	COG3620	sequence-specific DNA binding
CSW12_11400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSW12_11415	COG2356	endonuclease I
CSW12_11420	COG1288	antiporter activity
CSW12_11475	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_11485	COG2031	fatty acid transporter
CSW12_11500	COG1131	(ABC) transporter
CSW12_11505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CSW12_11515	COG2814	Major facilitator Superfamily
CSW12_11520	COG1846	Transcriptional regulator
CSW12_11535	COG0477	Major facilitator Superfamily
CSW12_11545	COG2843	Capsule synthesis protein
CSW12_11550	COG1876	peptidase activity
CSW12_11570	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_11570	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_11600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_11600	COG2207	Transcriptional regulator
CSW12_11610	COG0662	Cupin 2, conserved barrel domain protein
CSW12_11630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSW12_11650	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_11660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_11670	COG5002	protein histidine kinase activity
CSW12_11670	COG3850	Histidine kinase
CSW12_11690	COG0577	efflux transmembrane transporter activity
CSW12_11710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSW12_11720	COG1690	Belongs to the RtcB family
CSW12_11730	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSW12_11755	COG2814	Major facilitator Superfamily
CSW12_11810	COG1595	DNA-templated transcription, initiation
CSW12_11840	COG2040	homocysteine
CSW12_11845	COG0833	amino acid
CSW12_11860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_11860	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_11910	COG3850	Histidine kinase
CSW12_11910	COG5002	protein histidine kinase activity
CSW12_11915	COG0745	RESPONSE REGULATOR receiver
CSW12_11970	COG0346	lactoylglutathione lyase activity
CSW12_11985	COG1522	sequence-specific DNA binding
CSW12_11990	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_12000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSW12_12000	COG3320	Male sterility
CSW12_12005	COG0640	Transcriptional regulator
CSW12_12010	COG0346	lactoylglutathione lyase activity
CSW12_12015	COG0798	PFAM Bile acid sodium symporter
CSW12_12025	COG1575	Belongs to the MenA family. Type 1 subfamily
CSW12_12035	COG0726	polysaccharide deacetylase
CSW12_12055	COG2814	Major facilitator Superfamily
CSW12_12060	COG5609	conserved protein (DUF2294)
CSW12_12065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW12_12075	COG0288	reversible hydration of carbon dioxide
CSW12_12080	COG0657	acetylesterase activity
CSW12_12090	COG2814	Major facilitator Superfamily
CSW12_12100	COG0415	Belongs to the DNA photolyase family
CSW12_12120	COG1073	alpha beta
CSW12_12140	COG0598	Magnesium transport protein CorA
CSW12_12145	COG1846	Transcriptional regulator
CSW12_12180	COG1335	isochorismatase
CSW12_12185	COG2267	carboxylic ester hydrolase activity
CSW12_12195	COG0737	Belongs to the 5'-nucleotidase family
CSW12_12210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSW12_12220	COG1063	alcohol dehydrogenase
CSW12_12240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_12245	COG3848	Pyruvate phosphate dikinase
CSW12_12245	COG0574	Belongs to the PEP-utilizing enzyme family
CSW12_12265	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CSW12_12300	COG1960	acyl-CoA dehydrogenase activity
CSW12_12310	COG0640	Transcriptional regulator
CSW12_12325	COG1414	Transcriptional regulator
CSW12_12330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSW12_12335	COG1984	allophanate hydrolase subunit 2
CSW12_12405	COG1136	(ABC) transporter
CSW12_12405	COG0577	efflux transmembrane transporter activity
CSW12_12415	COG0745	RESPONSE REGULATOR receiver
CSW12_12430	COG4335	DNA alkylation repair
CSW12_12440	COG0833	amino acid
CSW12_12455	COG0730	response to heat
CSW12_12475	COG0456	acetyltransferase
CSW12_12475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW12_12495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_12500	COG0697	spore germination
CSW12_12515	COG0456	acetyltransferase
CSW12_12520	COG4977	sequence-specific DNA binding
CSW12_12545	COG4884	unkown
CSW12_12545	COG3831	ATPase activity
CSW12_12570	COG1846	Transcriptional regulator
CSW12_12575	COG0778	Nitroreductase
CSW12_12585	COG0714	Associated with various cellular activities
CSW12_12625	COG0753	catalase activity
CSW12_12650	COG0714	Associated with various cellular activities
CSW12_12675	COG0346	lactoylglutathione lyase activity
CSW12_12680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_12705	COG3655	Transcriptional regulator
CSW12_12715	COG1785	Belongs to the alkaline phosphatase family
CSW12_12720	COG2720	vancomycin resistance protein
CSW12_12730	COG3239	Fatty acid desaturase
CSW12_12745	COG0833	amino acid
CSW12_12755	COG1414	Transcriptional regulator
CSW12_12760	COG4187	Peptidase family M20/M25/M40
CSW12_12765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_12785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_12800	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_12825	COG1070	Carbohydrate kinase
CSW12_12830	COG2390	Transcriptional regulator
CSW12_12840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_12845	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_12850	COG1879	ABC-type sugar transport system periplasmic component
CSW12_12875	COG0277	FAD linked oxidase domain protein
CSW12_12890	COG3584	3D domain protein
CSW12_12890	COG1388	LysM domain
CSW12_12930	COG1605	Chorismate mutase
CSW12_12930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_12950	COG0287	Prephenate dehydrogenase
CSW12_12965	COG1309	transcriptional regulator
CSW12_12970	COG1033	growth of symbiont in host cell
CSW12_12970	COG2409	Drug exporters of the RND superfamily
CSW12_12975	COG0488	(ABC) transporter
CSW12_12980	COG1368	sulfuric ester hydrolase activity
CSW12_12985	COG0861	Integral membrane protein TerC family
CSW12_12995	COG0726	polysaccharide deacetylase
CSW12_13005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_13010	COG0346	lactoylglutathione lyase activity
CSW12_13015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_13020	COG4912	Dna alkylation repair
CSW12_13065	COG2746	aminoglycoside 3-N-acetyltransferase activity
CSW12_13095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_13100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_13105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSW12_13120	COG0628	permease
CSW12_13180	COG1131	(ABC) transporter
CSW12_13195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CSW12_13205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSW12_13210	COG0436	Aminotransferase
CSW12_13250	COG2226	methyltransferase
CSW12_13265	COG2261	transglycosylase associated protein
CSW12_13290	COG0477	Major facilitator Superfamily
CSW12_13290	COG2814	Major facilitator Superfamily
CSW12_13295	COG4533	DNA binding
CSW12_13300	COG0789	Transcriptional regulator
CSW12_13305	COG1664	Polymer-forming cytoskeletal
CSW12_13315	COG2814	Major facilitator Superfamily
CSW12_13350	COG1307	EDD domain protein, DegV family
CSW12_13355	COG1164	Oligoendopeptidase f
CSW12_13390	COG0745	RESPONSE REGULATOR receiver
CSW12_13395	COG3850	Histidine kinase
CSW12_13395	COG5002	protein histidine kinase activity
CSW12_13440	COG0667	Aldo Keto reductase
CSW12_13455	COG4948	Mandelate Racemase Muconate Lactonizing
CSW12_13465	COG4166	transmembrane transport
CSW12_13470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSW12_13480	COG0586	Pfam SNARE associated Golgi protein
CSW12_13525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_13530	COG3938	Belongs to the proline racemase family
CSW12_13540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSW12_13545	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_13550	COG1115	amino acid carrier protein
CSW12_13555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSW12_13570	COG3397	chitin binding
CSW12_13595	COG4637	Psort location Cytoplasmic, score
CSW12_13630	COG0514	ATP-dependent DNA helicase (RecQ)
CSW12_13635	COG2105	PFAM AIG2 family protein
CSW12_13645	COG3973	AAA domain
CSW12_13690	COG2315	Protein conserved in bacteria
CSW12_13700	COG2205	protein histidine kinase activity
CSW12_13720	COG3397	chitin binding
CSW12_13725	COG2153	protein acetylation
CSW12_13745	COG0740	serine-type endopeptidase activity
CSW12_13755	COG0517	IMP dehydrogenase activity
CSW12_13755	COG4175	Glycine betaine
CSW12_13760	COG4176	ABC-type proline glycine betaine transport system permease component
CSW12_13805	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_13815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_13820	COG0022	dehydrogenase e1 component
CSW12_13825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_13830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_13845	COG1959	2 iron, 2 sulfur cluster binding
CSW12_13860	COG1349	DNA-binding transcription factor activity
CSW12_13880	COG3284	Transcriptional regulator
CSW12_13965	COG3773	Cell wall hydrolase
CSW12_13965	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_13970	COG2959	enzyme of heme biosynthesis
CSW12_13985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_14015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSW12_14025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_14030	COG0697	spore germination
CSW12_14035	COG0201	protein transport
CSW12_14050	COG0737	Belongs to the 5'-nucleotidase family
CSW12_14055	COG3227	Zinc metalloprotease (Elastase)
CSW12_14060	COG1523	belongs to the glycosyl hydrolase 13 family
CSW12_14075	COG0076	glutamate decarboxylase activity
CSW12_14085	COG1073	alpha beta
CSW12_14090	COG0577	efflux transmembrane transporter activity
CSW12_14095	COG1136	(ABC) transporter
CSW12_14110	COG5002	protein histidine kinase activity
CSW12_14115	COG0745	RESPONSE REGULATOR receiver
CSW12_14150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_14195	COG0322	excinuclease ABC activity
CSW12_14235	COG4667	esterase of the alpha-beta hydrolase superfamily
CSW12_14260	COG3878	Protein conserved in bacteria
CSW12_14285	COG0592	DNA-directed DNA polymerase activity
CSW12_14300	COG2223	nitrite transmembrane transporter activity
CSW12_14345	COG0697	spore germination
CSW12_14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_14370	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_14395	COG0789	Transcriptional regulator
CSW12_14395	COG4978	Transcriptional regulator
CSW12_14400	COG2814	Major facilitator Superfamily
CSW12_14455	COG0671	phosphoesterase, PA-phosphatase related
CSW12_14460	COG0604	alcohol dehydrogenase
CSW12_14535	COG0582	viral genome integration into host DNA
CSW12_14540	COG2205	protein histidine kinase activity
CSW12_14565	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_14570	COG1819	glycosyl
CSW12_14590	COG5002	protein histidine kinase activity
CSW12_14595	COG0561	phosphatase activity
CSW12_14635	COG2124	cytochrome p450
CSW12_14700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSW12_14710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_14715	COG0460	homoserine dehydrogenase
CSW12_14735	COG0577	efflux transmembrane transporter activity
CSW12_14740	COG1136	(ABC) transporter
CSW12_14770	COG2205	protein histidine kinase activity
CSW12_14775	COG0745	RESPONSE REGULATOR receiver
CSW12_14785	COG3773	Cell wall hydrolase
CSW12_14790	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CSW12_14800	COG3386	PFAM SMP-30 Gluconolaconase
CSW12_14810	COG0693	protein deglycase activity
CSW12_14815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSW12_14820	COG2323	membrane
CSW12_14830	COG1063	alcohol dehydrogenase
CSW12_14845	COG2368	4-hydroxyphenylacetate
CSW12_14855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_14890	COG2226	methyltransferase
CSW12_14895	COG1733	regulation of RNA biosynthetic process
CSW12_14900	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_14940	COG2207	Transcriptional regulator
CSW12_14945	COG3227	Zinc metalloprotease (Elastase)
CSW12_14960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSW12_14985	COG1686	Belongs to the peptidase S11 family
CSW12_15010	COG0572	uridine kinase
CSW12_15030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_15035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSW12_15040	COG1024	Enoyl-CoA hydratase
CSW12_15045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSW12_15050	COG0511	ligase activity, forming carbon-carbon bonds
CSW12_15055	COG0439	Biotin carboxylase
CSW12_15060	COG1960	acyl-CoA dehydrogenase activity
CSW12_15075	COG1309	transcriptional regulator
CSW12_15085	COG1131	(ABC) transporter
CSW12_15095	COG1408	metallophosphoesterase
CSW12_15100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_15105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_15130	COG1595	DNA-templated transcription, initiation
CSW12_15135	COG0768	penicillin binding
CSW12_15145	COG2239	Acts as a magnesium transporter
CSW12_15170	COG1533	DNA photolyase activity
CSW12_15190	COG0814	amino acid
CSW12_15195	COG1760	l-serine dehydratase
CSW12_15200	COG1760	l-serine dehydratase
CSW12_15275	COG1404	Belongs to the peptidase S8 family
CSW12_15285	COG4585	Histidine kinase
CSW12_15310	COG0640	Transcriptional regulator
CSW12_15325	COG1846	Transcriptional regulator
CSW12_15345	COG1309	transcriptional regulator
CSW12_15350	COG0726	polysaccharide deacetylase
CSW12_15370	COG1396	sequence-specific DNA binding
CSW12_15390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_15395	COG0741	lytic transglycosylase activity
CSW12_15425	COG5002	protein histidine kinase activity
CSW12_15450	COG2207	Transcriptional regulator
CSW12_15475	COG0322	excinuclease ABC activity
CSW12_15480	COG0531	amino acid
CSW12_15485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_15495	COG0531	amino acid
CSW12_15500	COG0697	spore germination
CSW12_15510	COG0784	Response regulator, receiver
CSW12_15515	COG4191	Histidine kinase
CSW12_15525	COG1115	amino acid carrier protein
CSW12_15540	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CSW12_15565	COG2814	Major facilitator Superfamily
CSW12_15580	COG1686	Belongs to the peptidase S11 family
CSW12_15585	COG0110	maltose O-acetyltransferase activity
CSW12_15590	COG0730	response to heat
CSW12_15600	COG2002	toxin-antitoxin pair type II binding
CSW12_15630	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW12_15690	COG1846	Transcriptional regulator
CSW12_15695	COG3961	Belongs to the TPP enzyme family
CSW12_15700	COG2226	methyltransferase
CSW12_15710	COG0500	methyltransferase
CSW12_15710	COG3615	Tellurite resistance protein tehB
CSW12_15725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_15740	COG1846	Transcriptional regulator
CSW12_15760	COG2971	BadF BadG BcrA BcrD
CSW12_15785	COG1649	PFAM Uncharacterised BCR, COG1649
CSW12_15815	COG1595	DNA-templated transcription, initiation
CSW12_15820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_15855	COG1396	sequence-specific DNA binding
CSW12_15895	COG1132	(ABC) transporter
CSW12_15900	COG1132	(ABC) transporter
CSW12_15915	COG2258	MOSC domain
CSW12_15920	COG0583	DNA-binding transcription factor activity
CSW12_15940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW12_15945	COG0583	DNA-binding transcription factor activity
CSW12_15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_16010	COG1247	-acetyltransferase
CSW12_16045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_16100	COG0028	Belongs to the TPP enzyme family
CSW12_16115	COG2814	Major facilitator Superfamily
CSW12_16125	COG1136	(ABC) transporter
CSW12_16130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSW12_16135	COG1187	pseudouridine synthase activity
CSW12_16155	COG1115	amino acid carrier protein
CSW12_16165	COG2318	DinB family
CSW12_16175	COG0776	regulation of translation
CSW12_16190	COG2814	Major facilitator Superfamily
CSW12_16195	COG3251	PFAM MbtH domain protein
CSW12_16200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSW12_16205	COG1535	isochorismatase
CSW12_16205	COG3433	isochorismatase activity
CSW12_16210	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSW12_16215	COG1169	isochorismate synthase
CSW12_16220	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_16230	COG2223	nitrite transmembrane transporter activity
CSW12_16265	COG0419	ATPase involved in DNA repair
CSW12_16270	COG0420	3'-5' exonuclease activity
CSW12_16285	COG1024	Enoyl-CoA hydratase
CSW12_16290	COG1280	lysine exporter protein (LysE YggA)
CSW12_16300	COG2084	Dehydrogenase
CSW12_16305	COG1960	acyl-CoA dehydrogenase activity
CSW12_16310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CSW12_16315	COG2079	MmgE PrpD family protein
CSW12_16320	COG0372	Belongs to the citrate synthase family
CSW12_16325	COG4841	protein insertion into membrane
CSW12_16330	COG2814	Major facilitator Superfamily
CSW12_16340	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_16340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_16360	COG0300	oxidoreductase activity
CSW12_16450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_16455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSW12_16460	COG0671	phosphoesterase, PA-phosphatase related
CSW12_16470	COG4991	sh3 domain protein
CSW12_16470	COG0515	serine threonine protein kinase
CSW12_16470	COG3064	Membrane
CSW12_16505	COG1509	lysine 2,3-aminomutase activity
CSW12_16515	COG3829	transcription factor binding
CSW12_16520	COG0456	acetyltransferase
CSW12_16525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_16530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSW12_16535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSW12_16540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_16555	COG5506	Protein of unknown function (DUF1694)
CSW12_16560	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_16565	COG1253	flavin adenine dinucleotide binding
CSW12_16600	COG1174	glycine betaine transport
CSW12_16605	COG1125	glycine betaine transport
CSW12_16605	COG0517	IMP dehydrogenase activity
CSW12_16640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CSW12_16665	COG1064	alcohol dehydrogenase
CSW12_16670	COG0384	phenazine biosynthesis protein PhzF
CSW12_16675	COG1737	Transcriptional regulator
CSW12_16680	COG2197	response regulator
CSW12_16685	COG4585	Histidine kinase
CSW12_16685	COG2203	Gaf domain
CSW12_16690	COG0668	transmembrane transport
CSW12_16760	COG1396	sequence-specific DNA binding
CSW12_16795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_16800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_16805	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_16820	COG0367	asparagine synthase
CSW12_16825	COG0071	Belongs to the small heat shock protein (HSP20) family
CSW12_16830	COG1999	signal sequence binding
CSW12_16840	COG1307	EDD domain protein, DegV family
CSW12_16855	COG0805	protein transport
CSW12_16865	COG1272	protein, Hemolysin III
CSW12_16870	COG0204	Acyl-transferase
CSW12_16880	COG0768	penicillin binding
CSW12_16895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_16910	COG0546	phosphoglycolate phosphatase activity
CSW12_16920	COG4473	ABC transporter
CSW12_16925	COG1131	(ABC) transporter
CSW12_16935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSW12_16940	COG3655	Transcriptional regulator
CSW12_16950	COG0456	acetyltransferase
CSW12_16960	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_16970	COG2610	gluconate transmembrane transporter activity
CSW12_16995	COG0733	neurotransmitter:sodium symporter activity
CSW12_17050	COG1674	ftsk spoiiie
CSW12_17070	COG0017	Asparaginyl-tRNA synthetase
CSW12_17080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSW12_17120	COG0018	arginyl-trna synthetase
CSW12_17125	COG2521	methyltransferase
CSW12_17125	COG2136	Putative SAM-dependent methyltransferase
CSW12_17145	COG1413	lyase activity
CSW12_17160	COG0629	single-stranded DNA binding
CSW12_17175	COG0488	(ABC) transporter
CSW12_17180	COG1418	mRNA catabolic process
CSW12_17195	COG2359	stage V sporulation protein S
CSW12_17230	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CSW12_17235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSW12_17240	COG2146	nitrite reductase [NAD(P)H] activity
CSW12_17245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSW12_17245	COG1587	Uroporphyrinogen-III synthase
CSW12_17255	COG1648	precorrin-2 dehydrogenase activity
CSW12_17275	COG2223	nitrite transmembrane transporter activity
CSW12_17285	COG0314	molybdopterin synthase activity
CSW12_17290	COG0303	'Molybdopterin
CSW12_17295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_17300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSW12_17305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_17310	COG2181	nitrate reductase activity
CSW12_17315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CSW12_17320	COG1140	nitrate reductase beta subunit
CSW12_17325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSW12_17330	COG0714	Associated with various cellular activities
CSW12_17335	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CSW12_17340	COG1305	Transglutaminase-like
CSW12_17345	COG0386	Belongs to the glutathione peroxidase family
CSW12_17355	COG0426	domain, Protein
CSW12_17355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSW12_17370	COG1595	DNA-templated transcription, initiation
CSW12_17375	COG0604	alcohol dehydrogenase
CSW12_17385	COG0346	lactoylglutathione lyase activity
CSW12_17410	COG2226	methyltransferase
CSW12_17435	COG3874	Sporulation protein YtfJ
CSW12_17475	COG0456	acetyltransferase
CSW12_17505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_17510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_17515	COG1819	glycosyl
CSW12_17535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW12_17545	COG2814	Major facilitator Superfamily
CSW12_17550	COG1846	Transcriptional regulator
CSW12_17565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_17580	COG2211	Major facilitator Superfamily
CSW12_17595	COG1876	peptidase activity
CSW12_17610	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_17630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW12_17635	COG1114	Component of the transport system for branched-chain amino acids
CSW12_17660	COG1253	flavin adenine dinucleotide binding
CSW12_17665	COG2839	Protein conserved in bacteria
CSW12_17670	COG0702	epimerase
CSW12_17685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_17695	COG1607	acyl-coa hydrolase
CSW12_17700	COG3689	TIGRFAM TIGR03943 family protein
CSW12_17705	COG0701	Predicted permease
CSW12_17715	COG2244	polysaccharide biosynthetic process
CSW12_17720	COG0586	Pfam SNARE associated Golgi protein
CSW12_17725	COG1051	belongs to the nudix hydrolase family
CSW12_17730	COG5337	Spore coat protein CotH
CSW12_17755	COG4166	transmembrane transport
CSW12_17765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSW12_17775	COG0702	epimerase
CSW12_17785	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSW12_17790	COG0456	acetyltransferase
CSW12_17795	COG0523	cobalamin synthesis protein
CSW12_17800	COG4989	oxidoreductase activity
CSW12_17805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_17810	COG1231	oxidoreductase activity
CSW12_17835	COG0783	Belongs to the Dps family
CSW12_17840	COG3949	Membrane
CSW12_17860	COG0840	transmembrane signaling receptor activity
CSW12_17885	COG2814	Major facilitator Superfamily
CSW12_17890	COG0667	Aldo Keto reductase
CSW12_17895	COG0640	Transcriptional regulator
CSW12_17900	COG1404	Belongs to the peptidase S8 family
CSW12_17905	COG2002	toxin-antitoxin pair type II binding
CSW12_17910	COG0577	efflux transmembrane transporter activity
CSW12_17945	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSW12_17955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_17960	COG1279	arginine transmembrane transporter activity
CSW12_17965	COG2814	Major facilitator Superfamily
CSW12_17975	COG1082	Xylose isomerase domain protein TIM barrel
CSW12_17990	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_17995	COG4264	IucA IucC family
CSW12_18005	COG1247	-acetyltransferase
CSW12_18010	COG1285	pathogenesis
CSW12_18025	COG5002	protein histidine kinase activity
CSW12_18030	COG0745	RESPONSE REGULATOR receiver
CSW12_18040	COG1316	TRANSCRIPTIONal
CSW12_18065	COG0460	homoserine dehydrogenase
CSW12_18085	COG0726	polysaccharide deacetylase
CSW12_18100	COG0300	oxidoreductase activity
CSW12_18105	COG5002	protein histidine kinase activity
CSW12_18110	COG0745	RESPONSE REGULATOR receiver
CSW12_18125	COG0791	NLP P60 protein
CSW12_18125	COG1388	LysM domain
CSW12_18140	COG1686	Belongs to the peptidase S11 family
CSW12_18175	COG1216	Glycosyl transferase, family 2
CSW12_18185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSW12_18190	COG4988	ABC transporter
CSW12_18195	COG1294	oxidase, subunit
CSW12_18200	COG1271	oxidase subunit
CSW12_18220	COG1942	4-Oxalocrotonate Tautomerase
CSW12_18230	COG0583	DNA-binding transcription factor activity
CSW12_18250	COG0411	ABC transporter
CSW12_18260	COG0523	cobalamin synthesis protein
CSW12_18270	COG1231	oxidoreductase activity
CSW12_18280	COG0628	permease
CSW12_18295	COG0778	Nitroreductase
CSW12_18300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSW12_18305	COG1959	2 iron, 2 sulfur cluster binding
CSW12_18310	COG0583	DNA-binding transcription factor activity
CSW12_18315	COG0697	spore germination
CSW12_18320	COG4549	nuclear export factor GLE1
CSW12_18325	COG1276	copper resistance
CSW12_18325	COG2372	response to copper ion
CSW12_18340	COG1114	Component of the transport system for branched-chain amino acids
CSW12_18375	COG2132	Multicopper oxidase
CSW12_18385	COG0006	proline dipeptidase activity
CSW12_18395	COG4846	Membrane protein involved in cytochrome C biogenesis
CSW12_18405	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CSW12_18410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_18420	COG2390	Transcriptional regulator
CSW12_18425	COG1309	transcriptional regulator
CSW12_18445	COG0456	acetyltransferase
CSW12_18460	COG2309	aminopeptidase activity
CSW12_18495	COG0531	amino acid
CSW12_18500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSW12_18515	COG1914	H( )-stimulated, divalent metal cation uptake system
CSW12_18520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_18565	COG4166	transmembrane transport
CSW12_18570	COG1309	transcriptional regulator
CSW12_18575	COG2814	Major facilitator Superfamily
CSW12_18595	COG0427	acetyl-CoA hydrolase
CSW12_18600	COG3279	Response regulator of the LytR AlgR family
CSW12_18610	COG3384	dioxygenase
CSW12_18615	COG2814	Major facilitator Superfamily
CSW12_18635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSW12_18655	COG0028	Belongs to the TPP enzyme family
CSW12_18660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_18670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_18700	COG2323	membrane
CSW12_18705	COG5566	PFAM Mor transcription activator
CSW12_18720	COG0733	neurotransmitter:sodium symporter activity
CSW12_18740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_18745	COG2223	nitrite transmembrane transporter activity
CSW12_18750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSW12_18760	COG0477	Major facilitator Superfamily
CSW12_18770	COG1695	Transcriptional regulator
CSW12_18840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_18845	COG0784	Response regulator, receiver
CSW12_18850	COG4191	Histidine kinase
CSW12_18855	COG0281	malic enzyme
CSW12_18860	COG1027	Aspartate ammonia-lyase
CSW12_18870	COG0528	UMP kinase activity
CSW12_18875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_18890	COG1131	(ABC) transporter
CSW12_18930	COG2733	membrane
CSW12_18950	COG0457	Tetratricopeptide repeat
CSW12_18965	COG0785	Cytochrome C biogenesis protein
CSW12_18985	COG3340	Belongs to the peptidase S51 family
CSW12_18990	COG0534	Mate efflux family protein
CSW12_19015	COG0789	Transcriptional regulator
CSW12_19020	COG1757	Na H antiporter
CSW12_19035	COG0701	Predicted permease
CSW12_19045	COG0523	cobalamin synthesis protein
CSW12_19055	COG0697	spore germination
CSW12_19060	COG1802	Transcriptional regulator
CSW12_19090	COG0367	asparagine synthase
CSW12_19165	COG1177	transmembrane transport
CSW12_19175	COG3842	ATPase activity
CSW12_19205	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_19250	COG4786	Flagellar basal body rod
CSW12_19255	COG1419	protein localization to endoplasmic reticulum
CSW12_19260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSW12_19265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSW12_19275	COG1987	bacterial-type flagellum assembly
CSW12_19280	COG1338	Plays a role in the flagellum-specific transport system
CSW12_19290	COG1776	CheC inhibitor of MCP methylation
CSW12_19290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_19295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_19305	COG0741	lytic transglycosylase activity
CSW12_19310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_19315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_19320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_19325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_19335	COG0835	chemotaxis
CSW12_19335	COG0784	Response regulator, receiver
CSW12_19370	COG1157	protein secretion by the type III secretion system
CSW12_19380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_19385	COG1766	The M ring may be actively involved in energy transduction
CSW12_19390	COG1677	Flagellar hook-basal body complex protein FliE
CSW12_19395	COG1558	bacterial-type flagellum-dependent cell motility
CSW12_19400	COG1815	bacterial-type flagellum-dependent cell motility
CSW12_19415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSW12_19420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_19445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW12_19460	COG1776	CheC inhibitor of MCP methylation
CSW12_19460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_19465	COG2198	Histidine kinase
CSW12_19465	COG0643	Histidine kinase
CSW12_19470	COG2201	protein-glutamate methylesterase activity
CSW12_19475	COG1360	Flagellar Motor Protein
CSW12_19480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSW12_19490	COG1923	regulation of RNA biosynthetic process
CSW12_19540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CSW12_19545	COG2323	membrane
CSW12_19555	COG4978	Transcriptional regulator
CSW12_19555	COG0789	Transcriptional regulator
CSW12_19560	COG0475	glutathione-regulated potassium exporter activity
CSW12_19570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_19575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_19595	COG1280	lysine exporter protein (LysE YggA)
CSW12_19600	COG3403	YqcI/YcgG family
CSW12_19635	COG0328	RNA-DNA hybrid ribonuclease activity
CSW12_19655	COG0454	-acetyltransferase
CSW12_19670	COG0438	transferase activity, transferring glycosyl groups
CSW12_19675	COG1215	transferase activity, transferring glycosyl groups
CSW12_19690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW12_19715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_19765	COG0456	acetyltransferase
CSW12_19775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_19785	COG2311	Membrane
CSW12_19790	COG2233	PERMEase
CSW12_19800	COG0024	Methionine aminopeptidase
CSW12_19810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CSW12_19815	COG1199	ATP-dependent helicase activity
CSW12_19825	COG0116	Belongs to the methyltransferase superfamily
CSW12_19885	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_19885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_19895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSW12_19900	COG3935	DnaD domain protein
CSW12_19920	COG1199	ATP-dependent helicase activity
CSW12_19920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSW12_19960	COG0438	transferase activity, transferring glycosyl groups
CSW12_19980	COG1694	Mazg nucleotide pyrophosphohydrolase
CSW12_19990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_20000	COG2738	Putative neutral zinc metallopeptidase
CSW12_20015	COG4347	Protein of unknown function (DUF1405)
CSW12_20025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSW12_20025	COG2010	Cytochrome c
CSW12_20030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSW12_20050	COG0457	Tetratricopeptide repeat
CSW12_20075	COG0142	geranyltranstransferase activity
CSW12_20085	COG0142	geranyltranstransferase activity
CSW12_20100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_20120	COG0456	acetyltransferase
CSW12_20125	COG1073	alpha beta
CSW12_20140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW12_20140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW12_20145	COG0307	riboflavin synthase, alpha
CSW12_20175	COG2226	methyltransferase
CSW12_20175	COG1073	alpha beta
CSW12_20190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_20210	COG0737	Belongs to the 5'-nucleotidase family
CSW12_20220	COG1522	sequence-specific DNA binding
CSW12_20265	COG0300	oxidoreductase activity
CSW12_20270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_20275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_20280	COG1760	l-serine dehydratase
CSW12_20285	COG1760	l-serine dehydratase
CSW12_20320	COG1285	pathogenesis
CSW12_20340	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW12_20345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_20360	COG1376	ErfK ybiS ycfS ynhG family protein
CSW12_20365	COG4129	membrane
CSW12_20370	COG1126	abc transporter atp-binding protein
CSW12_20375	COG0765	amino acid transport
CSW12_20380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_20400	COG2323	membrane
CSW12_20405	COG0772	Belongs to the SEDS family
CSW12_20415	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_20420	COG0022	dehydrogenase e1 component
CSW12_20425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_20430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_20440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSW12_20445	COG0280	phosphate acetyltransferase
CSW12_20455	COG3829	transcription factor binding
CSW12_20455	COG3290	protein histidine kinase activity
CSW12_20465	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_20470	COG3093	addiction module antidote protein HigA
CSW12_20495	COG0750	zinc metalloprotease
CSW12_20500	COG0497	DNA recombination
CSW12_20510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CSW12_20520	COG0142	geranyltranstransferase activity
CSW12_20545	COG1302	Protein conserved in bacteria
CSW12_20550	COG0439	Biotin carboxylase
CSW12_20555	COG0511	ligase activity, forming carbon-carbon bonds
CSW12_20600	COG3854	ATPases associated with a variety of cellular activities
CSW12_20625	COG0006	proline dipeptidase activity
CSW12_20640	COG3872	metal-dependent enzyme
CSW12_20650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSW12_20685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_20695	COG1609	Transcriptional regulator
CSW12_20705	COG2076	Multidrug Resistance protein
CSW12_20710	COG2076	Multidrug Resistance protein
CSW12_20745	COG1131	(ABC) transporter
CSW12_20750	COG1725	Transcriptional regulator
CSW12_20785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_20865	COG1459	type II secretion system
CSW12_20870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW12_20930	COG0646	methionine synthase
CSW12_20930	COG1410	methionine synthase
CSW12_20935	COG0646	methionine synthase
CSW12_20935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSW12_20940	COG0626	cystathionine gamma-synthase activity
CSW12_20945	COG0626	cystathionine gamma-synthase activity
CSW12_20965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_20975	COG1940	carbohydrate kinase activity
CSW12_20980	COG4483	Protein conserved in bacteria
CSW12_20985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSW12_20995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_21000	COG0704	Plays a role in the regulation of phosphate uptake
CSW12_21010	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_21015	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_21020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW12_21030	COG0477	Major facilitator Superfamily
CSW12_21035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSW12_21045	COG5521	maltodextrose utilization protein MalA
CSW12_21060	COG0735	belongs to the Fur family
CSW12_21065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSW12_21070	COG1121	(ABC) transporter
CSW12_21075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_21105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSW12_21110	COG2384	SAM-dependent methyltransferase
CSW12_21120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSW12_21125	COG0358	DNA primase activity
CSW12_21145	COG0517	IMP dehydrogenase activity
CSW12_21160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSW12_21165	COG0295	cytidine deaminase activity
CSW12_21170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CSW12_21180	COG1480	7TM receptor with intracellular HD hydrolase
CSW12_21185	COG1702	phosphate starvation-inducible protein PhoH
CSW12_21205	COG1610	YqeY-like protein
CSW12_21220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSW12_21225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSW12_21255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSW12_21260	COG1733	regulation of RNA biosynthetic process
CSW12_21285	COG1466	dna polymerase III delta subunit
CSW12_21295	COG2333	competence protein COMEC
CSW12_21295	COG0658	competence protein
CSW12_21300	COG2131	deaminase
CSW12_21320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_21325	COG2226	methyltransferase
CSW12_21330	COG0799	negative regulation of ribosome biogenesis
CSW12_21335	COG1713	HD superfamily hydrolase involved in NAD metabolism
CSW12_21345	COG1534	Rna-binding protein
CSW12_21355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CSW12_21360	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CSW12_21375	COG1191	sigma factor activity
CSW12_21395	COG0778	Nitroreductase
CSW12_21400	COG2357	RelA SpoT domain protein
CSW12_21410	COG1785	Belongs to the alkaline phosphatase family
CSW12_21425	COG2267	carboxylic ester hydrolase activity
CSW12_21460	COG1404	Belongs to the peptidase S8 family
CSW12_21465	COG3186	Phenylalanine-4-hydroxylase
CSW12_21475	COG2514	catechol 2,3-dioxygenase activity
CSW12_21480	COG2259	Doxx family
CSW12_21525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_21540	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_21540	COG1454	alcohol dehydrogenase
CSW12_21545	COG0626	cystathionine gamma-synthase activity
CSW12_21550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_21575	COG0768	penicillin binding
CSW12_21605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSW12_21635	COG0628	permease
CSW12_21655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSW12_21670	COG1104	cysteine desulfurase activity
CSW12_21675	COG1959	2 iron, 2 sulfur cluster binding
CSW12_21680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSW12_21700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSW12_21725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSW12_21735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSW12_21735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSW12_21740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSW12_21745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW12_21745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW12_21755	COG2244	polysaccharide biosynthetic process
CSW12_21760	COG2323	membrane
CSW12_21770	COG1862	Preprotein translocase
CSW12_21800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSW12_21830	COG0157	Belongs to the NadC ModD family
CSW12_21835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CSW12_21840	COG1104	cysteine desulfurase activity
CSW12_21845	COG1827	regulation of RNA biosynthetic process
CSW12_21850	COG2258	MOSC domain
CSW12_21855	COG0077	Prephenate dehydratase
CSW12_21860	COG0577	efflux transmembrane transporter activity
CSW12_21865	COG0577	efflux transmembrane transporter activity
CSW12_21870	COG1136	(ABC) transporter
CSW12_21875	COG5002	protein histidine kinase activity
CSW12_21880	COG0745	RESPONSE REGULATOR receiver
CSW12_21890	COG3290	protein histidine kinase activity
CSW12_21900	COG2868	ribosomal protein
CSW12_21910	COG1530	ribonuclease E activity
CSW12_21915	COG1994	Peptidase M50
CSW12_21920	COG0739	heme binding
CSW12_21925	COG2894	cell division
CSW12_21940	COG1792	Involved in formation and maintenance of cell shape
CSW12_21945	COG1077	Cell shape determining protein MreB Mrl
CSW12_21970	COG0285	dihydrofolate synthase activity
CSW12_21985	COG1388	LysM domain
CSW12_21995	COG0113	porphobilinogen synthase activity
CSW12_22000	COG1587	Uroporphyrinogen-III synthase
CSW12_22010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW12_22020	COG1846	Transcriptional regulator
CSW12_22030	COG1764	response to oxidative stress
CSW12_22045	COG0470	DNA polymerase III
CSW12_22045	COG1067	ATP-dependent peptidase activity
CSW12_22105	COG0622	Phosphoesterase
CSW12_22120	COG5401	PFAM Sporulation and spore germination
CSW12_22140	COG1309	transcriptional regulator
CSW12_22150	COG2197	response regulator
CSW12_22160	COG0402	S-adenosylhomocysteine deaminase activity
CSW12_22165	COG1983	PspC domain protein
CSW12_22170	COG1396	sequence-specific DNA binding
CSW12_22175	COG0697	spore germination
CSW12_22185	COG1959	2 iron, 2 sulfur cluster binding
CSW12_22190	COG1668	transmembrane transport
CSW12_22195	COG4152	abc transporter atp-binding protein
CSW12_22200	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_22205	COG1360	Flagellar Motor Protein
CSW12_22210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSW12_22220	COG1876	peptidase activity
CSW12_22225	COG0824	Thioesterase
CSW12_22230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSW12_22235	COG1053	succinate dehydrogenase
CSW12_22240	COG2009	succinate dehydrogenase
CSW12_22245	COG1719	4-vinyl reductase, 4VR
CSW12_22255	COG3118	belongs to the thioredoxin family
CSW12_22260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CSW12_22265	COG2086	electron transfer activity
CSW12_22270	COG1024	Enoyl-CoA hydratase
CSW12_22275	COG1309	transcriptional regulator
CSW12_22280	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_22315	COG2318	DinB family
CSW12_22345	COG1131	(ABC) transporter
CSW12_22350	COG2205	protein histidine kinase activity
CSW12_22355	COG0745	RESPONSE REGULATOR receiver
CSW12_22365	COG4895	conserved protein (DUF2196)
CSW12_22370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSW12_22380	COG4509	Sortase family
CSW12_22385	COG1120	ATPase activity
CSW12_22400	COG5386	Cell surface protein
CSW12_22410	COG5386	Cell surface protein
CSW12_22415	COG1114	Component of the transport system for branched-chain amino acids
CSW12_22420	COG1187	pseudouridine synthase activity
CSW12_22435	COG1796	DNA polymerase
CSW12_22435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSW12_22440	COG1286	toxin biosynthetic process
CSW12_22470	COG0017	Asparaginyl-tRNA synthetase
CSW12_22485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW12_22495	COG1418	mRNA catabolic process
CSW12_22515	COG2814	Major facilitator Superfamily
CSW12_22520	COG1566	PFAM secretion protein HlyD family protein
CSW12_22525	COG1309	transcriptional regulator
CSW12_22530	COG1363	Peptidase, m42
CSW12_22555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSW12_22570	COG1484	DNA-dependent DNA replication
CSW12_22575	COG3611	Membrane attachment protein
CSW12_22585	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CSW12_22595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW12_22600	COG0237	dephospho-CoA kinase activity
CSW12_22605	COG1971	Probably functions as a manganese efflux pump
CSW12_22615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_22615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_22620	COG5002	protein histidine kinase activity
CSW12_22625	COG0745	RESPONSE REGULATOR receiver
CSW12_22650	COG0538	isocitrate dehydrogenase activity
CSW12_22655	COG0372	Belongs to the citrate synthase family
CSW12_22670	COG0628	permease
CSW12_22675	COG3030	protein affecting phage T7 exclusion by the F plasmid
CSW12_22700	COG1725	Transcriptional regulator
CSW12_22705	COG0281	malic enzyme
CSW12_22710	COG0587	DNA-directed DNA polymerase activity
CSW12_22725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CSW12_22740	COG4109	DRTGG domain
CSW12_22755	COG0006	proline dipeptidase activity
CSW12_22785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_22790	COG0662	Cupin 2, conserved barrel domain protein
CSW12_22805	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_22810	COG0589	response to stress
CSW12_22855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_22880	COG0827	DNA restriction-modification system
CSW12_22885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSW12_22890	COG3874	Sporulation protein YtfJ
CSW12_22910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CSW12_22930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_22945	COG1104	cysteine desulfurase activity
CSW12_22955	COG0583	DNA-binding transcription factor activity
CSW12_22960	COG0697	spore germination
CSW12_22965	COG1309	transcriptional regulator
CSW12_22970	COG1956	GAF domain-containing protein
CSW12_22975	COG0626	cystathionine gamma-synthase activity
CSW12_23015	COG1595	DNA-templated transcription, initiation
CSW12_23025	COG0110	maltose O-acetyltransferase activity
CSW12_23030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_23035	COG0454	-acetyltransferase
CSW12_23040	COG0517	IMP dehydrogenase activity
CSW12_23045	COG0123	including yeast histone deacetylase and acetoin utilization protein
CSW12_23060	COG0745	RESPONSE REGULATOR receiver
CSW12_23065	COG5002	protein histidine kinase activity
CSW12_23070	COG0666	response to abiotic stimulus
CSW12_23100	COG1609	Transcriptional regulator
CSW12_23115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_23115	COG1605	Chorismate mutase
CSW12_23120	COG1605	Chorismate mutase
CSW12_23120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_23125	COG4851	CamS sex pheromone cAM373 precursor
CSW12_23130	COG3118	belongs to the thioredoxin family
CSW12_23140	COG2309	aminopeptidase activity
CSW12_23160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_23165	COG0697	spore germination
CSW12_23170	COG0789	Transcriptional regulator
CSW12_23185	COG1674	ftsk spoiiie
CSW12_23190	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_23200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW12_23210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_23215	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CSW12_23220	COG1363	Peptidase, m42
CSW12_23230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_23250	COG0510	thiamine kinase activity
CSW12_23255	COG1523	belongs to the glycosyl hydrolase 13 family
CSW12_23265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_23270	COG1349	DNA-binding transcription factor activity
CSW12_23275	COG1187	pseudouridine synthase activity
CSW12_23280	COG2244	polysaccharide biosynthetic process
CSW12_23285	COG2081	HI0933 family
CSW12_23295	COG2814	Major facilitator Superfamily
CSW12_23305	COG3832	glyoxalase III activity
CSW12_23330	COG1329	Transcriptional regulator
CSW12_23355	COG0314	molybdopterin synthase activity
CSW12_23360	COG1763	Mo-molybdopterin cofactor biosynthetic process
CSW12_23365	COG0303	'Molybdopterin
CSW12_23375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_23380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSW12_23405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_23415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSW12_23455	COG2814	Major facilitator Superfamily
CSW12_23460	COG0475	glutathione-regulated potassium exporter activity
CSW12_23465	COG0490	domain, Protein
CSW12_23470	COG0582	viral genome integration into host DNA
CSW12_23485	COG1136	(ABC) transporter
CSW12_23505	COG1242	4 iron, 4 sulfur cluster binding
CSW12_23510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CSW12_23520	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_23545	COG2267	carboxylic ester hydrolase activity
CSW12_23550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSW12_23555	COG0671	phosphoesterase, PA-phosphatase related
CSW12_23560	COG0438	transferase activity, transferring glycosyl groups
CSW12_23670	COG5002	protein histidine kinase activity
CSW12_23675	COG3852	Histidine kinase
CSW12_23680	COG2267	carboxylic ester hydrolase activity
CSW12_23685	COG1368	sulfuric ester hydrolase activity
CSW12_23700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_23705	COG1116	anion transmembrane transporter activity
CSW12_23710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_23735	COG0494	nUDIX hydrolase
CSW12_23775	COG0288	reversible hydration of carbon dioxide
CSW12_23780	COG1271	oxidase subunit
CSW12_23785	COG1294	oxidase, subunit
CSW12_23805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_23830	COG1842	Phage shock protein A
CSW12_23855	COG3859	Proton-coupled thiamine transporter YuaJ
CSW12_23860	COG5002	protein histidine kinase activity
CSW12_23865	COG0745	RESPONSE REGULATOR receiver
CSW12_23895	COG1597	lipid kinase activity
CSW12_23925	COG0586	Pfam SNARE associated Golgi protein
CSW12_23935	COG0577	efflux transmembrane transporter activity
CSW12_23940	COG1136	(ABC) transporter
CSW12_23945	COG3708	Transcriptional regulator
CSW12_23945	COG2207	Transcriptional regulator
CSW12_23955	COG5658	integral membrane protein
CSW12_23960	COG0640	Transcriptional regulator
CSW12_23965	COG0745	RESPONSE REGULATOR receiver
CSW12_23970	COG2205	protein histidine kinase activity
CSW12_23985	COG0577	efflux transmembrane transporter activity
CSW12_23990	COG0577	efflux transmembrane transporter activity
CSW12_23995	COG1136	(ABC) transporter
CSW12_24000	COG0577	efflux transmembrane transporter activity
CSW12_24035	COG3964	amidohydrolase
CSW12_24060	COG4948	Mandelate Racemase Muconate Lactonizing
CSW12_24080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CSW12_24085	COG0596	Alpha beta hydrolase
CSW12_24095	COG1169	isochorismate synthase
CSW12_24100	COG1575	Belongs to the MenA family. Type 1 subfamily
CSW12_24105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSW12_24110	COG1278	Cold shock
CSW12_24140	COG0058	SHG alpha-glucan phosphorylase activity
CSW12_24150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CSW12_24170	COG1404	Belongs to the peptidase S8 family
CSW12_24185	COG1309	transcriptional regulator
CSW12_24325	COG1285	pathogenesis
CSW12_24330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW12_24350	COG2155	Conserved Protein
CSW12_24355	COG1098	S1 RNA binding domain
CSW12_24360	COG0436	Aminotransferase
CSW12_24365	COG1522	sequence-specific DNA binding
CSW12_24370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_24375	COG2267	carboxylic ester hydrolase activity
CSW12_24385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CSW12_24400	COG5018	Exonuclease
CSW12_24405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_24425	COG0423	glycine-tRNA ligase activity
CSW12_24430	COG2050	protein possibly involved in aromatic compounds catabolism
CSW12_24440	COG1268	BioY protein
CSW12_24445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSW12_24450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSW12_24465	COG3584	3D domain protein
CSW12_24480	COG1252	NADH dehydrogenase
CSW12_24495	COG3708	Transcriptional regulator
CSW12_24510	COG1683	Conserved Protein
CSW12_24545	COG0316	Belongs to the HesB IscA family
CSW12_24560	COG1252	NADH dehydrogenase
CSW12_24570	COG2274	protein secretion by the type I secretion system
CSW12_24575	COG0390	transport system, permease component
CSW12_24580	COG2824	Alkylphosphonate utilization operon protein PhnA
CSW12_24605	COG4837	Protein of unknown function (DUF1462)
CSW12_24610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSW12_24620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSW12_24625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSW12_24645	COG1358	cellular component organization or biogenesis
CSW12_24655	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_24660	COG0647	UMP catabolic process
CSW12_24670	COG2445	Protein of unknown function DUF86
CSW12_24675	COG1494	fructose-1,6-bisphosphatase
CSW12_24695	COG4470	Protein conserved in bacteria
CSW12_24705	COG0789	Transcriptional regulator
CSW12_24710	COG4377	Putative membrane peptidase family (DUF2324)
CSW12_24735	COG0739	heme binding
CSW12_24745	COG3377	Domain of unknown function (DUF1805)
CSW12_24760	COG0719	Fe-S assembly protein
CSW12_24765	COG0822	iron-sulfur transferase activity
CSW12_24770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSW12_24775	COG0719	Fe-S assembly protein
CSW12_24780	COG0396	ATPase activity
CSW12_24785	COG1464	Belongs to the NlpA lipoprotein family
CSW12_24790	COG1464	Belongs to the NlpA lipoprotein family
CSW12_24795	COG2011	ABC-type metal ion transport system permease component
CSW12_24810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_24815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSW12_24830	COG1393	Belongs to the ArsC family
CSW12_24850	COG0039	L-malate dehydrogenase activity
CSW12_24870	COG1309	transcriptional regulator
CSW12_24875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_24880	COG1960	acyl-CoA dehydrogenase activity
CSW12_24885	COG0183	Belongs to the thiolase family
CSW12_24890	COG1024	Enoyl-CoA hydratase
CSW12_24890	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSW12_24900	COG1686	Belongs to the peptidase S11 family
CSW12_24915	COG0011	TIGRFAM Protein of
CSW12_24920	COG0840	transmembrane signaling receptor activity
CSW12_24935	COG2814	Major facilitator Superfamily
CSW12_24940	COG0531	amino acid
CSW12_24965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_25005	COG0586	Pfam SNARE associated Golgi protein
CSW12_25015	COG1376	ErfK ybiS ycfS ynhG family protein
CSW12_25020	COG0745	RESPONSE REGULATOR receiver
CSW12_25025	COG5002	protein histidine kinase activity
CSW12_25055	COG0840	transmembrane signaling receptor activity
CSW12_25060	COG2151	metal-sulfur cluster biosynthetic enzyme
CSW12_25065	COG3227	Zinc metalloprotease (Elastase)
CSW12_25085	COG0586	Pfam SNARE associated Golgi protein
CSW12_25090	COG0475	glutathione-regulated potassium exporter activity
CSW12_25095	COG0490	domain, Protein
CSW12_25105	COG1115	amino acid carrier protein
CSW12_25110	COG0783	Belongs to the Dps family
CSW12_25125	COG1611	Belongs to the LOG family
CSW12_25135	COG1528	Iron-storage protein
CSW12_25150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_25155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_25160	COG1115	amino acid carrier protein
CSW12_25165	COG1115	amino acid carrier protein
CSW12_25170	COG2910	NAD(P)H-binding
CSW12_25195	COG0656	L-ascorbic acid biosynthetic process
CSW12_25200	COG2814	Major facilitator Superfamily
CSW12_25210	COG1733	regulation of RNA biosynthetic process
CSW12_25220	COG1252	NADH dehydrogenase
CSW12_25275	COG0488	(ABC) transporter
CSW12_25280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_25285	COG3223	Belongs to the PsiE family
CSW12_25295	COG1335	isochorismatase
CSW12_25310	COG1522	sequence-specific DNA binding
CSW12_25315	COG0288	reversible hydration of carbon dioxide
CSW12_25320	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CSW12_25325	COG2233	PERMEase
CSW12_25370	COG0557	exoribonuclease II activity
CSW12_25375	COG1647	Serine aminopeptidase, S33
CSW12_25380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW12_25385	COG1346	cytolysis
CSW12_25420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW12_25435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSW12_25450	COG4152	abc transporter atp-binding protein
CSW12_25455	COG4585	Histidine kinase
CSW12_25485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_25500	COG2323	membrane
CSW12_25515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_25525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CSW12_25535	COG1051	belongs to the nudix hydrolase family
CSW12_25545	COG0492	ferredoxin-NADP+ reductase activity
CSW12_25550	COG0457	Tetratricopeptide repeat
CSW12_25555	COG0110	maltose O-acetyltransferase activity
CSW12_25575	COG1950	PFAM Membrane protein of
CSW12_25580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSW12_25600	COG0789	Transcriptional regulator
CSW12_25630	COG0583	DNA-binding transcription factor activity
CSW12_25640	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSW12_25645	COG0488	(ABC) transporter
CSW12_25655	COG1132	(ABC) transporter
CSW12_25660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_25665	COG0793	Belongs to the peptidase S41A family
CSW12_25665	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_25670	COG2177	Part of the ABC transporter FtsEX involved in
CSW12_25675	COG2884	Cell division ATP-binding protein ftsE
CSW12_25705	COG1131	(ABC) transporter
CSW12_25735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSW12_25740	COG1278	Cold shock
CSW12_25745	COG1040	competence protein
CSW12_25755	COG1388	LysM domain
CSW12_25755	COG0791	NLP P60 protein
CSW12_25760	COG1733	regulation of RNA biosynthetic process
CSW12_25770	COG1307	EDD domain protein, DegV family
CSW12_25775	COG1739	Uncharacterized protein family UPF0029
CSW12_25780	COG1316	TRANSCRIPTIONal
CSW12_25785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSW12_25795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSW12_25805	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSW12_25805	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CSW12_25825	COG1486	melibiose metabolic process
CSW12_25830	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_25835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_25855	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_25865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_25870	COG1301	dicarboxylic acid transport
CSW12_25885	COG1511	domain protein
CSW12_25890	COG0583	DNA-binding transcription factor activity
CSW12_25895	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CSW12_25905	COG1271	oxidase subunit
CSW12_25910	COG1294	oxidase, subunit
CSW12_25915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_25945	COG1620	l-lactate permease
CSW12_25960	COG2389	metal-binding protein
CSW12_25975	COG1368	sulfuric ester hydrolase activity
CSW12_25990	COG1388	LysM domain
CSW12_25990	COG0791	NLP P60 protein
CSW12_25995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_26005	COG1215	transferase activity, transferring glycosyl groups
CSW12_26015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_26025	COG3584	3D domain protein
CSW12_26025	COG1388	LysM domain
CSW12_26050	COG4715	Zinc finger, swim domain protein
CSW12_26055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_26085	COG1191	sigma factor activity
CSW12_26095	COG0577	efflux transmembrane transporter activity
CSW12_26100	COG1136	(ABC) transporter
CSW12_26120	COG2271	Major facilitator Superfamily
CSW12_26135	COG5002	protein histidine kinase activity
CSW12_26140	COG0745	RESPONSE REGULATOR receiver
CSW12_26145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSW12_26165	COG1442	glycosyl transferase family 8
CSW12_26165	COG1216	Glycosyl transferase, family 2
CSW12_26175	COG0438	transferase activity, transferring glycosyl groups
CSW12_26180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW12_26190	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSW12_26200	COG1086	Polysaccharide biosynthesis protein
CSW12_26205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSW12_26210	COG4464	protein tyrosine phosphatase activity
CSW12_26215	COG0489	protein tyrosine kinase activity
CSW12_26220	COG3944	biosynthesis protein
CSW12_26225	COG0489	protein tyrosine kinase activity
CSW12_26240	COG1609	Transcriptional regulator
CSW12_26250	COG0739	heme binding
CSW12_26265	COG3279	Response regulator of the LytR AlgR family
CSW12_26270	COG2385	sporulation resulting in formation of a cellular spore
CSW12_26275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSW12_26285	COG4836	Membrane
CSW12_26290	COG1007	ATP synthesis coupled electron transport
CSW12_26295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSW12_26300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW12_26310	COG0839	Belongs to the complex I subunit 6 family
CSW12_26330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSW12_26345	COG3300	MHYT domain
CSW12_26345	COG5001	Diguanylate cyclase
CSW12_26400	COG0356	it plays a direct role in the translocation of protons across the membrane
CSW12_26440	COG0698	ribose 5-phosphate isomerase
CSW12_26455	COG2190	(PTS) system
CSW12_26460	COG2259	Doxx family
CSW12_26465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSW12_26480	COG0009	L-threonylcarbamoyladenylate synthase
CSW12_26500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSW12_26520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSW12_26525	COG1494	fructose-1,6-bisphosphatase
CSW12_26545	COG4821	SIS domain
CSW12_26565	COG1960	acyl-CoA dehydrogenase activity
CSW12_26570	COG1960	acyl-CoA dehydrogenase activity
CSW12_26575	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSW12_26580	COG0183	Belongs to the thiolase family
CSW12_26585	COG0247	lactate metabolic process
CSW12_26585	COG2181	nitrate reductase activity
CSW12_26595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_26605	COG3300	MHYT domain
CSW12_26605	COG5001	Diguanylate cyclase
CSW12_26620	COG3227	Zinc metalloprotease (Elastase)
CSW12_26625	COG2197	response regulator
CSW12_26630	COG4585	Histidine kinase
CSW12_26635	COG0842	Transport permease protein
CSW12_26640	COG1131	(ABC) transporter
CSW12_26645	COG0024	Methionine aminopeptidase
CSW12_26660	COG2234	aminopeptidase activity
CSW12_26670	COG1595	DNA-templated transcription, initiation
CSW12_26680	COG4506	Protein conserved in bacteria
CSW12_26685	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_26710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CSW12_26715	COG2814	Major facilitator Superfamily
CSW12_26720	COG0789	Transcriptional regulator
CSW12_26725	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_26730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_26740	COG1994	Peptidase M50
CSW12_26750	COG1078	dGTPase activity
CSW12_26755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_26760	COG1120	ATPase activity
CSW12_26765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_26790	COG0280	phosphate acetyltransferase
CSW12_26805	COG3773	Cell wall hydrolase
CSW12_26815	COG2363	Small membrane protein
CSW12_26830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW12_26835	COG2233	PERMEase
CSW12_26840	COG0561	phosphatase activity
CSW12_26845	COG2814	Major facilitator Superfamily
CSW12_26855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CSW12_26860	COG1131	(ABC) transporter
CSW12_26865	COG2755	lipolytic protein G-D-S-L family
CSW12_26870	COG1609	Transcriptional regulator
CSW12_26880	COG0460	homoserine dehydrogenase
CSW12_26900	COG1011	Hydrolase
CSW12_26905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_26915	COG2197	response regulator
CSW12_26920	COG2203	Gaf domain
CSW12_26920	COG4585	Histidine kinase
CSW12_26925	COG0351	phosphomethylpyrimidine kinase
CSW12_26930	COG3706	GGDEF domain
CSW12_26935	COG2879	small protein
CSW12_26940	COG1966	Carbon starvation protein
CSW12_26945	COG3279	Response regulator of the LytR AlgR family
CSW12_26950	COG0477	Major facilitator Superfamily
CSW12_26960	COG0438	transferase activity, transferring glycosyl groups
CSW12_26975	COG0840	transmembrane signaling receptor activity
CSW12_26985	COG1607	acyl-coa hydrolase
CSW12_26995	COG1216	Glycosyl transferase, family 2
CSW12_27005	COG0488	(ABC) transporter
CSW12_27020	COG0463	Glycosyl transferase, family 2
CSW12_27025	COG1309	transcriptional regulator
CSW12_27030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW12_27035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_27035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_27040	COG0628	permease
CSW12_27060	COG3275	phosphorelay sensor kinase activity
CSW12_27065	COG2814	Major facilitator Superfamily
CSW12_27070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_27075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CSW12_27105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSW12_27110	COG2801	Transposase and inactivated derivatives
CSW12_27115	COG2801	Transposase and inactivated derivatives
CSW12_27135	COG1695	Transcriptional regulator
CSW12_27140	COG1132	(ABC) transporter
CSW12_27145	COG0515	serine threonine protein kinase
CSW12_27175	COG1272	protein, Hemolysin III
CSW12_27200	COG1164	Oligoendopeptidase f
CSW12_27210	COG5002	protein histidine kinase activity
CSW12_27225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_27230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSW12_27235	COG4853	Protein conserved in bacteria
CSW12_27245	COG5002	protein histidine kinase activity
CSW12_27250	COG0745	RESPONSE REGULATOR receiver
CSW12_27280	COG0305	Participates in initiation and elongation during chromosome replication
CSW12_27290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CSW12_27295	COG4241	membrane
CSW12_27305	COG0629	single-stranded DNA binding
CSW12_27315	COG0012	GTP binding
CSW12_27320	COG4481	Protein conserved in bacteria
CSW12_27325	COG0668	transmembrane transport
CSW12_27335	COG1475	DNA binding
CSW12_27340	COG1192	Involved in chromosome partitioning
CSW12_27365	COG1847	R3H domain protein
CSW12_27390	COG0592	DNA-directed DNA polymerase activity
CSW12_27395	COG2501	S4 domain
CSW12_27405	COG0187	DNA topoisomerase II activity
CSW12_27410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSW12_27445	COG0516	GMP reductase activity
CSW12_27445	COG0517	IMP dehydrogenase activity
CSW12_27450	COG1686	Belongs to the peptidase S11 family
CSW12_27480	COG1428	Deoxynucleoside kinase
CSW12_27485	COG1428	Deoxynucleoside kinase
CSW12_27490	COG1335	isochorismatase
CSW12_27500	COG0590	tRNA wobble adenosine to inosine editing
CSW12_27510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSW12_27565	COG1982	Orn Lys Arg decarboxylase major
CSW12_27575	COG0470	DNA polymerase III
CSW12_27580	COG1774	PSP1 C-terminal conserved region
CSW12_27590	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CSW12_27600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSW12_27605	COG2002	toxin-antitoxin pair type II binding
CSW12_27615	COG0084	hydrolase, TatD family'
CSW12_27635	COG4466	Protein conserved in bacteria
CSW12_27650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSW12_27655	COG0251	oxidation-reduction process
CSW12_27670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSW12_27685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSW12_27690	COG2002	toxin-antitoxin pair type II binding
CSW12_27695	COG2244	polysaccharide biosynthetic process
CSW12_27700	COG3956	TIGRFAM MazG family protein
CSW12_27705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSW12_27725	COG1098	S1 RNA binding domain
CSW12_27740	COG2208	phosphoserine phosphatase activity
CSW12_27755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSW12_27770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_27775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSW12_27780	COG0512	Glutamine amidotransferase of anthranilate synthase
CSW12_27785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_27790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSW12_27795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSW12_27800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSW12_27805	COG1396	sequence-specific DNA binding
CSW12_27810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW12_27900	COG3880	PFAM UvrB UvrC protein
CSW12_27910	COG0542	response to heat
CSW12_27915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSW12_27925	COG4956	integral membrane protein (PIN domain superfamily)
CSW12_27945	COG1045	serine acetyltransferase
CSW12_27960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW12_27965	COG3688	RNA-binding protein containing a PIN domain
CSW12_27975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSW12_27980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW12_27985	COG0250	Participates in transcription elongation, termination and antitermination
CSW12_28010	COG2813	Specifically methylates the guanine in position
CSW12_28025	COG1358	cellular component organization or biogenesis
CSW12_28135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CSW12_28160	COG0201	protein transport
CSW12_28170	COG0024	Methionine aminopeptidase
CSW12_28180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSW12_28215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CSW12_28240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_28245	COG0489	protein tyrosine kinase activity
CSW12_28255	COG2194	sulfuric ester hydrolase activity
CSW12_28260	COG0726	polysaccharide deacetylase
CSW12_28345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CSW12_28350	COG4856	YbbR-like protein
CSW12_28390	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_28395	COG2011	ABC-type metal ion transport system permease component
CSW12_28400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSW12_28405	COG1464	Belongs to the NlpA lipoprotein family
CSW12_28410	COG0604	alcohol dehydrogenase
CSW12_28420	COG0277	FAD linked oxidase domain protein
CSW12_28425	COG2271	Major facilitator Superfamily
CSW12_28435	COG2814	Major facilitator Superfamily
CSW12_28455	COG0601	transmembrane transport
CSW12_28460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_28465	COG0444	Belongs to the ABC transporter superfamily
CSW12_28470	COG4608	Belongs to the ABC transporter superfamily
CSW12_28475	COG4166	transmembrane transport
CSW12_28490	COG4166	transmembrane transport
CSW12_28495	COG4166	transmembrane transport
CSW12_28500	COG0656	L-ascorbic acid biosynthetic process
CSW12_28525	COG4149	molybdate abc transporter
CSW12_28530	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSW12_28535	COG1910	domain protein
CSW12_28550	COG0697	spore germination
CSW12_28565	COG0204	Acyl-transferase
CSW12_28580	COG1609	Transcriptional regulator
CSW12_28590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_28610	COG5298	Protein conserved in bacteria
CSW12_28640	COG0488	(ABC) transporter
CSW12_28655	COG0747	negative chemotaxis
CSW12_28660	COG0601	transmembrane transport
CSW12_28670	COG0444	Belongs to the ABC transporter superfamily
CSW12_28675	COG4608	Belongs to the ABC transporter superfamily
CSW12_28680	COG0561	phosphatase activity
CSW12_28710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CSW12_28715	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSW12_28725	COG0531	amino acid
CSW12_28730	COG2814	Major facilitator Superfamily
CSW12_28740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSW12_28755	COG0705	Rhomboid family
CSW12_28765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSW12_28770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW12_28775	COG0864	Transcriptional regulator
CSW12_28780	COG2337	Toxic component of a toxin-antitoxin (TA) module
CSW12_28785	COG2183	response to ionizing radiation
CSW12_28885	COG0802	atpase or kinase
CSW12_28890	COG1214	PFAM Peptidase M22, glycoprotease
CSW12_28895	COG0456	acetyltransferase
CSW12_28905	COG0488	(ABC) transporter
CSW12_28920	COG1266	CAAX protease self-immunity
CSW12_28940	COG2252	PERMEase
CSW12_28950	COG5002	protein histidine kinase activity
CSW12_28980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSW12_29000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_29005	COG0506	proline dehydrogenase activity
CSW12_29055	COG1215	transferase activity, transferring glycosyl groups
CSW12_29075	COG0697	spore germination
CSW12_29130	COG1215	transferase activity, transferring glycosyl groups
CSW12_29185	COG3316	Transposase and inactivated derivatives
CSW12_29220	COG2801	Transposase and inactivated derivatives
CSW12_29225	COG3316	Transposase and inactivated derivatives
CSW12_29475	COG3209	COG3209 Rhs family protein
CSW12_29480	COG0582	viral genome integration into host DNA
CSW12_29490	COG3316	Transposase and inactivated derivatives
CSW12_29495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_29520	COG3316	Transposase and inactivated derivatives
CSW12_29530	COG1136	(ABC) transporter
CSW12_29535	COG3316	Transposase and inactivated derivatives
CSW12_29590	COG3316	Transposase and inactivated derivatives
CSW12_29600	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CSW12_29605	COG3316	Transposase and inactivated derivatives
CSW12_29615	COG4644	lycopene metabolic process
CSW12_29645	COG3316	Transposase and inactivated derivatives
CSW12_29650	COG2801	Transposase and inactivated derivatives
CSW12_29715	COG3316	Transposase and inactivated derivatives
CSW12_29750	COG2801	Transposase and inactivated derivatives
CSW12_29755	COG3316	Transposase and inactivated derivatives
CSW12_29815	COG1396	sequence-specific DNA binding
CSW12_29845	COG0457	Tetratricopeptide repeat
CSW12_29950	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_29990	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_29995	COG0288	reversible hydration of carbon dioxide
CSW12_30015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSW12_30015	COG2755	lipolytic protein G-D-S-L family
CSW12_30045	COG3316	Transposase and inactivated derivatives
CSW12_30110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_30135	COG4644	lycopene metabolic process
CSW12_30160	COG0270	DNA (cytosine-5-)-methyltransferase activity
CSW12_30175	COG3316	Transposase and inactivated derivatives
CSW12_30190	COG2002	toxin-antitoxin pair type II binding
CSW12_30195	COG1923	regulation of RNA biosynthetic process
CSW12_30240	COG3316	Transposase and inactivated derivatives
CSW12_30265	COG1215	transferase activity, transferring glycosyl groups
CSW12_30300	COG3316	Transposase and inactivated derivatives
CSW12_30305	COG0697	spore germination
CSW12_30315	COG4644	lycopene metabolic process
CSW12_30430	COG1923	regulation of RNA biosynthetic process
CSW12_30435	COG2002	toxin-antitoxin pair type II binding
CSW12_30525	COG0791	NLP P60 protein
CSW12_30525	COG0741	lytic transglycosylase activity
CSW12_30575	COG1396	sequence-specific DNA binding
CSW12_30595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSW12_30635	COG3344	reverse transcriptase
CSW12_30690	COG1785	Belongs to the alkaline phosphatase family
CSW12_30725	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_30740	COG2755	lipolytic protein G-D-S-L family
CSW12_30740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSW12_30765	COG0288	reversible hydration of carbon dioxide
CSW12_30770	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_30885	COG1073	alpha beta
CSW12_30895	COG0745	RESPONSE REGULATOR receiver
CSW12_30945	COG1396	sequence-specific DNA binding
CSW12_31015	COG3505	Type IV secretory pathway VirD4
CSW12_31050	COG0791	NLP P60 protein
CSW12_31050	COG3883	PFAM NLP P60 protein
CSW12_31120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW12_31140	COG2002	toxin-antitoxin pair type II binding
CSW12_31155	COG3341	Caulimovirus viroplasmin
CSW12_31155	COG0328	RNA-DNA hybrid ribonuclease activity
CSW12_31235	COG3344	reverse transcriptase
CSW12_31270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII