locus-tag	class	description
BCM0045_0002	COG0592	DNA-directed DNA polymerase activity
BCM0045_0003	COG2501	S4 domain
BCM0045_0005	COG0187	DNA topoisomerase II activity
BCM0045_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCM0045_0008	COG0516	GMP reductase activity
BCM0045_0008	COG0517	IMP dehydrogenase activity
BCM0045_0009	COG1686	Belongs to the peptidase S11 family
BCM0045_0014	COG1428	Deoxynucleoside kinase
BCM0045_0015	COG1428	Deoxynucleoside kinase
BCM0045_0016	COG1335	isochorismatase
BCM0045_0017	COG0590	tRNA wobble adenosine to inosine editing
BCM0045_0018	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCM0045_0024	COG1982	Orn Lys Arg decarboxylase major
BCM0045_0026	COG0470	DNA polymerase III
BCM0045_0027	COG1774	PSP1 C-terminal conserved region
BCM0045_0029	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCM0045_0031	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCM0045_0032	COG2002	toxin-antitoxin pair type II binding
BCM0045_0033	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0045_0033	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0045_0034	COG0084	hydrolase, TatD family'
BCM0045_0035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCM0045_0038	COG4466	Protein conserved in bacteria
BCM0045_0041	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCM0045_0042	COG0251	oxidation-reduction process
BCM0045_0048	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCM0045_0049	COG2002	toxin-antitoxin pair type II binding
BCM0045_0050	COG2244	polysaccharide biosynthetic process
BCM0045_0051	COG3956	TIGRFAM MazG family protein
BCM0045_0052	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCM0045_0056	COG1098	S1 RNA binding domain
BCM0045_0057	COG2208	phosphoserine phosphatase activity
BCM0045_0059	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCM0045_0060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCM0045_0063	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0045_0064	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCM0045_0065	COG0512	Glutamine amidotransferase of anthranilate synthase
BCM0045_0066	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0045_0067	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCM0045_0068	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCM0045_0069	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCM0045_0070	COG1396	sequence-specific DNA binding
BCM0045_0071	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCM0045_0074	COG3880	PFAM UvrB UvrC protein
BCM0045_0076	COG0542	response to heat
BCM0045_0077	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCM0045_0079	COG4956	integral membrane protein (PIN domain superfamily)
BCM0045_0083	COG1045	serine acetyltransferase
BCM0045_0086	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCM0045_0087	COG3688	RNA-binding protein containing a PIN domain
BCM0045_0089	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCM0045_0090	COG0250	Participates in transcription elongation, termination and antitermination
BCM0045_0091	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCM0045_0095	COG2813	Specifically methylates the guanine in position
BCM0045_0098	COG1358	cellular component organization or biogenesis
BCM0045_0112	COG0255	Belongs to the universal ribosomal protein uL29 family
BCM0045_0124	COG0201	protein transport
BCM0045_0126	COG0024	Methionine aminopeptidase
BCM0045_0128	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCM0045_0134	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCM0045_0139	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0045_0140	COG0489	protein tyrosine kinase activity
BCM0045_0142	COG2194	sulfuric ester hydrolase activity
BCM0045_0143	COG0726	polysaccharide deacetylase
BCM0045_0147	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCM0045_0148	COG4856	YbbR-like protein
BCM0045_0152	COG0596	Alpha beta hydrolase
BCM0045_0156	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCM0045_0162	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_0163	COG2011	ABC-type metal ion transport system permease component
BCM0045_0165	COG1464	Belongs to the NlpA lipoprotein family
BCM0045_0166	COG0604	alcohol dehydrogenase
BCM0045_0168	COG0277	FAD linked oxidase domain protein
BCM0045_0169	COG2271	Major facilitator Superfamily
BCM0045_0171	COG2814	Major facilitator Superfamily
BCM0045_0174	COG0601	transmembrane transport
BCM0045_0175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0045_0176	COG0444	Belongs to the ABC transporter superfamily
BCM0045_0177	COG4608	Belongs to the ABC transporter superfamily
BCM0045_0178	COG4166	transmembrane transport
BCM0045_0180	COG2207	Transcriptional regulator
BCM0045_0182	COG1309	transcriptional regulator
BCM0045_0184	COG4166	transmembrane transport
BCM0045_0185	COG4166	transmembrane transport
BCM0045_0186	COG0656	L-ascorbic acid biosynthetic process
BCM0045_0187	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0045_0190	COG4149	molybdate abc transporter
BCM0045_0191	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCM0045_0192	COG1910	domain protein
BCM0045_0194	COG0697	spore germination
BCM0045_0196	COG0204	Acyl-transferase
BCM0045_0197	COG1609	Transcriptional regulator
BCM0045_0199	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_0201	COG0084	hydrolase, TatD family'
BCM0045_0203	COG5298	Protein conserved in bacteria
BCM0045_0208	COG0488	(ABC) transporter
BCM0045_0209	COG4585	Histidine kinase
BCM0045_0210	COG2197	response regulator
BCM0045_0211	COG1131	(ABC) transporter
BCM0045_0212	COG0842	Transport permease protein
BCM0045_0212	COG1511	domain protein
BCM0045_0213	COG0842	Transport permease protein
BCM0045_0215	COG0747	negative chemotaxis
BCM0045_0216	COG0601	transmembrane transport
BCM0045_0217	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0045_0218	COG0444	Belongs to the ABC transporter superfamily
BCM0045_0219	COG4608	Belongs to the ABC transporter superfamily
BCM0045_0220	COG0561	phosphatase activity
BCM0045_0223	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BCM0045_0224	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCM0045_0226	COG2814	Major facilitator Superfamily
BCM0045_0228	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCM0045_0230	COG4294	response to UV
BCM0045_0231	COG0705	Rhomboid family
BCM0045_0231	COG0457	Tetratricopeptide repeat
BCM0045_0233	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCM0045_0234	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCM0045_0236	COG0864	Transcriptional regulator
BCM0045_0237	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCM0045_0238	COG2183	response to ionizing radiation
BCM0045_0240	COG0802	atpase or kinase
BCM0045_0241	COG1214	PFAM Peptidase M22, glycoprotease
BCM0045_0242	COG0456	acetyltransferase
BCM0045_0244	COG0488	(ABC) transporter
BCM0045_0247	COG1266	CAAX protease self-immunity
BCM0045_0251	COG2252	PERMEase
BCM0045_0253	COG5002	protein histidine kinase activity
BCM0045_0255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCM0045_0261	COG2205	protein histidine kinase activity
BCM0045_0262	COG0745	RESPONSE REGULATOR receiver
BCM0045_0263	COG0697	spore germination
BCM0045_0265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCM0045_0266	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCM0045_0267	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCM0045_0269	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCM0045_0272	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCM0045_0274	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCM0045_0276	COG0151	Belongs to the GarS family
BCM0045_0281	COG0210	DNA helicase
BCM0045_0283	COG4851	CamS sex pheromone cAM373 precursor
BCM0045_0287	COG1335	isochorismatase
BCM0045_0288	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCM0045_0289	COG2011	ABC-type metal ion transport system permease component
BCM0045_0290	COG1464	Belongs to the NlpA lipoprotein family
BCM0045_0292	COG0003	Pfam Anion-transporting ATPase
BCM0045_0293	COG1846	Transcriptional regulator
BCM0045_0294	COG4682	membrane
BCM0045_0298	COG1597	lipid kinase activity
BCM0045_0299	COG0546	phosphoglycolate phosphatase activity
BCM0045_0300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCM0045_0302	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_0303	COG2076	Multidrug Resistance protein
BCM0045_0305	COG2309	aminopeptidase activity
BCM0045_0310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_0311	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCM0045_0312	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCM0045_0314	COG5002	protein histidine kinase activity
BCM0045_0315	COG4807	Protein conserved in bacteria
BCM0045_0320	COG1757	Na H antiporter
BCM0045_0321	COG1473	amidohydrolase
BCM0045_0324	COG0450	alkyl hydroperoxide reductase
BCM0045_0328	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_0329	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_0330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_0334	COG0166	Belongs to the GPI family
BCM0045_0342	COG3541	Predicted nucleotidyltransferase
BCM0045_0343	COG2814	Major facilitator Superfamily
BCM0045_0344	COG0723	plastoquinol--plastocyanin reductase activity
BCM0045_0344	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0045_0349	COG0765	amino acid transport
BCM0045_0350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_0352	COG0840	transmembrane signaling receptor activity
BCM0045_0353	COG0840	transmembrane signaling receptor activity
BCM0045_0354	COG0277	FAD linked oxidase domain protein
BCM0045_0359	COG0366	Alpha amylase catalytic
BCM0045_0360	COG1263	PTS System
BCM0045_0360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_0360	COG2190	(PTS) system
BCM0045_0366	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCM0045_0367	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCM0045_0370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0045_0372	COG1116	anion transmembrane transporter activity
BCM0045_0373	COG0488	(ABC) transporter
BCM0045_0383	COG2270	Major facilitator Superfamily
BCM0045_0389	COG2310	stress, protein
BCM0045_0390	COG2310	stress, protein
BCM0045_0391	COG2310	stress, protein
BCM0045_0392	COG0861	Integral membrane protein TerC family
BCM0045_0394	COG3853	Toxic anion resistance protein (TelA)
BCM0045_0397	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCM0045_0399	COG1295	ribonuclease BN
BCM0045_0401	COG2217	Heavy metal translocating P-type atpase
BCM0045_0402	COG0697	spore germination
BCM0045_0404	COG0681	Belongs to the peptidase S26 family
BCM0045_0406	COG0586	Pfam SNARE associated Golgi protein
BCM0045_0409	COG3871	stress protein (general stress protein 26)
BCM0045_0410	COG0387	Pfam Sodium calcium exchanger
BCM0045_0412	COG0535	radical SAM domain protein
BCM0045_0416	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCM0045_0417	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCM0045_0418	COG0101	tRNA pseudouridine synthase activity
BCM0045_0422	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0045_0428	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_0428	COG1263	PTS System
BCM0045_0429	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0045_0433	COG0463	Glycosyl transferase, family 2
BCM0045_0435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCM0045_0438	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCM0045_0444	COG1228	amidohydrolase
BCM0045_0445	COG1090	epimerase
BCM0045_0451	COG1988	membrane-bound metal-dependent
BCM0045_0452	COG1194	a g-specific adenine glycosylase
BCM0045_0457	COG1132	(ABC) transporter
BCM0045_0458	COG4129	membrane
BCM0045_0459	COG0069	glutamate synthase activity
BCM0045_0459	COG0067	glutamate synthase
BCM0045_0459	COG0070	glutamate synthase
BCM0045_0461	COG4555	ABC transporter
BCM0045_0465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCM0045_0466	COG0735	belongs to the Fur family
BCM0045_0478	COG1201	RNA secondary structure unwinding
BCM0045_0494	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCM0045_0498	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCM0045_0499	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCM0045_0500	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCM0045_0502	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCM0045_0503	COG5001	Diguanylate cyclase
BCM0045_0503	COG1716	ATPase activity
BCM0045_0504	COG2766	serine protein kinase
BCM0045_0508	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0045_0510	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCM0045_0511	COG2268	Band 7 protein
BCM0045_0513	COG3290	protein histidine kinase activity
BCM0045_0514	COG4565	transcriptional regulatory protein
BCM0045_0515	COG2851	Citrate transporter
BCM0045_0519	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCM0045_0520	COG3842	ATPase activity
BCM0045_0521	COG1175	transmembrane transport
BCM0045_0522	COG0395	ABC-type sugar transport system, permease component
BCM0045_0525	COG0745	RESPONSE REGULATOR receiver
BCM0045_0526	COG5002	protein histidine kinase activity
BCM0045_0531	COG4990	cell redox homeostasis
BCM0045_0533	COG0697	spore germination
BCM0045_0534	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_0536	COG5002	protein histidine kinase activity
BCM0045_0537	COG0745	RESPONSE REGULATOR receiver
BCM0045_0539	COG0456	acetyltransferase
BCM0045_0539	COG0454	-acetyltransferase
BCM0045_0540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCM0045_0541	COG3383	formate dehydrogenase (NAD+) activity
BCM0045_0542	COG2427	Protein of unknown function (DUF1641)
BCM0045_0545	COG0531	amino acid
BCM0045_0547	COG0640	Transcriptional regulator
BCM0045_0548	COG2217	Heavy metal translocating P-type atpase
BCM0045_0549	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCM0045_0552	COG3227	Zinc metalloprotease (Elastase)
BCM0045_0556	COG2720	vancomycin resistance protein
BCM0045_0557	COG1316	TRANSCRIPTIONal
BCM0045_0558	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_0559	COG0346	lactoylglutathione lyase activity
BCM0045_0560	COG1253	flavin adenine dinucleotide binding
BCM0045_0561	COG1027	Aspartate ammonia-lyase
BCM0045_0562	COG1620	l-lactate permease
BCM0045_0565	COG3104	oligopeptide transport
BCM0045_0566	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_0567	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_0568	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_0570	COG2226	methyltransferase
BCM0045_0571	COG0156	8-amino-7-oxononanoate synthase activity
BCM0045_0572	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCM0045_0573	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCM0045_0575	COG4548	von Willebrand factor, type A
BCM0045_0576	COG0714	Associated with various cellular activities
BCM0045_0577	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0045_0580	COG0531	amino acid
BCM0045_0581	COG2188	Transcriptional regulator
BCM0045_0582	COG1263	PTS System
BCM0045_0582	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_0583	COG0366	Alpha amylase catalytic
BCM0045_0586	COG0697	spore germination
BCM0045_0588	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0045_0589	COG1115	amino acid carrier protein
BCM0045_0590	COG1126	abc transporter atp-binding protein
BCM0045_0591	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_0592	COG0765	amino acid transport
BCM0045_0593	COG0765	amino acid transport
BCM0045_0594	COG0833	amino acid
BCM0045_0599	COG2378	regulation of single-species biofilm formation
BCM0045_0600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCM0045_0601	COG5002	protein histidine kinase activity
BCM0045_0604	COG0659	secondary active sulfate transmembrane transporter activity
BCM0045_0606	COG4166	transmembrane transport
BCM0045_0608	COG0601	transmembrane transport
BCM0045_0609	COG4608	Belongs to the ABC transporter superfamily
BCM0045_0611	COG2271	Major facilitator Superfamily
BCM0045_0612	COG1846	Transcriptional regulator
BCM0045_0613	COG0477	Major facilitator Superfamily
BCM0045_0614	COG1609	Transcriptional regulator
BCM0045_0615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCM0045_0618	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCM0045_0619	COG1879	ABC-type sugar transport system periplasmic component
BCM0045_0624	COG1063	alcohol dehydrogenase
BCM0045_0627	COG3568	Endonuclease Exonuclease Phosphatase
BCM0045_0633	COG0840	transmembrane signaling receptor activity
BCM0045_0634	COG1388	LysM domain
BCM0045_0634	COG3584	3D domain protein
BCM0045_0635	COG1476	TRANSCRIPTIONal
BCM0045_0638	COG3104	oligopeptide transport
BCM0045_0640	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_0641	COG1464	Belongs to the NlpA lipoprotein family
BCM0045_0642	COG1960	acyl-CoA dehydrogenase activity
BCM0045_0643	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCM0045_0644	COG2011	ABC-type metal ion transport system permease component
BCM0045_0647	COG1113	amino acid transport
BCM0045_0648	COG2252	PERMEase
BCM0045_0651	COG2153	protein acetylation
BCM0045_0653	COG0569	domain protein
BCM0045_0653	COG0475	glutathione-regulated potassium exporter activity
BCM0045_0656	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCM0045_0657	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCM0045_0658	COG4990	cell redox homeostasis
BCM0045_0661	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0045_0662	COG0697	spore germination
BCM0045_0663	COG0531	amino acid
BCM0045_0665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0045_0666	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0045_0667	COG1918	ferrous iron import across plasma membrane
BCM0045_0667	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0045_0668	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCM0045_0669	COG0573	inorganic phosphate transmembrane transporter activity
BCM0045_0670	COG0581	inorganic phosphate transmembrane transporter activity
BCM0045_0671	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCM0045_0672	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BCM0045_0676	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCM0045_0677	COG1116	anion transmembrane transporter activity
BCM0045_0678	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0045_0679	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0045_0680	COG0352	thiamine-phosphate diphosphorylase activity
BCM0045_0681	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0045_0682	COG2104	thiamine diphosphate biosynthetic process
BCM0045_0684	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0045_0685	COG0351	phosphomethylpyrimidine kinase
BCM0045_0692	COG2205	protein histidine kinase activity
BCM0045_0693	COG2814	Major facilitator Superfamily
BCM0045_0694	COG1846	Transcriptional regulator
BCM0045_0698	COG1136	(ABC) transporter
BCM0045_0700	COG2252	PERMEase
BCM0045_0701	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_0705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0045_0713	COG0778	Nitroreductase
BCM0045_0714	COG2719	SpoVR family
BCM0045_0717	COG3591	Belongs to the peptidase S1B family
BCM0045_0719	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCM0045_0720	COG1937	Protein conserved in bacteria
BCM0045_0721	COG0425	Belongs to the sulfur carrier protein TusA family
BCM0045_0721	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0045_0722	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_0722	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0045_0723	COG0425	Belongs to the sulfur carrier protein TusA family
BCM0045_0724	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0045_0726	COG2210	Belongs to the sulfur carrier protein TusA family
BCM0045_0727	COG0730	response to heat
BCM0045_0729	COG1316	TRANSCRIPTIONal
BCM0045_0730	COG0604	alcohol dehydrogenase
BCM0045_0731	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCM0045_0734	COG3711	transcriptional antiterminator
BCM0045_0734	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0045_0735	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0045_0736	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0045_0740	COG3584	3D domain protein
BCM0045_0740	COG1388	LysM domain
BCM0045_0741	COG0577	efflux transmembrane transporter activity
BCM0045_0742	COG1136	(ABC) transporter
BCM0045_0744	COG5522	Integral membrane protein (intg_mem_TP0381)
BCM0045_0747	COG0577	efflux transmembrane transporter activity
BCM0045_0748	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_0749	COG3546	catalase activity
BCM0045_0756	COG0586	Pfam SNARE associated Golgi protein
BCM0045_0764	COG0531	amino acid
BCM0045_0765	COG0475	glutathione-regulated potassium exporter activity
BCM0045_0767	COG1737	Transcriptional regulator
BCM0045_0769	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_0769	COG1263	PTS System
BCM0045_0771	COG2259	Doxx family
BCM0045_0774	COG1522	sequence-specific DNA binding
BCM0045_0777	COG2076	Multidrug Resistance protein
BCM0045_0778	COG1309	transcriptional regulator
BCM0045_0779	COG2814	Major facilitator Superfamily
BCM0045_0780	COG0657	acetylesterase activity
BCM0045_0781	COG1309	transcriptional regulator
BCM0045_0782	COG2124	cytochrome p450
BCM0045_0784	COG1063	alcohol dehydrogenase
BCM0045_0785	COG4533	DNA binding
BCM0045_0786	COG2211	Major facilitator Superfamily
BCM0045_0788	COG0693	protein deglycase activity
BCM0045_0789	COG0753	catalase activity
BCM0045_0791	COG0531	amino acid
BCM0045_0792	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_0793	COG1132	(ABC) transporter
BCM0045_0794	COG1132	(ABC) transporter
BCM0045_0795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_0796	COG0765	amino acid transport
BCM0045_0797	COG1126	abc transporter atp-binding protein
BCM0045_0800	COG0189	ligase activity
BCM0045_0806	COG0028	Belongs to the TPP enzyme family
BCM0045_0807	COG3527	Alpha-acetolactate decarboxylase
BCM0045_0809	COG0561	phosphatase activity
BCM0045_0810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCM0045_0813	COG0659	secondary active sulfate transmembrane transporter activity
BCM0045_0817	COG2244	polysaccharide biosynthetic process
BCM0045_0820	COG5263	repeat protein
BCM0045_0820	COG4193	domain, Protein
BCM0045_0823	COG1024	Enoyl-CoA hydratase
BCM0045_0827	COG1363	Peptidase, m42
BCM0045_0842	COG0582	viral genome integration into host DNA
BCM0045_0851	COG0322	excinuclease ABC activity
BCM0045_0853	COG1649	PFAM Uncharacterised BCR, COG1649
BCM0045_0859	COG0601	transmembrane transport
BCM0045_0860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0045_0861	COG0444	Belongs to the ABC transporter superfamily
BCM0045_0862	COG4608	Belongs to the ABC transporter superfamily
BCM0045_0868	COG0477	Major facilitator Superfamily
BCM0045_0870	COG3290	protein histidine kinase activity
BCM0045_0871	COG4565	transcriptional regulatory protein
BCM0045_0872	COG3181	Tripartite tricarboxylate transporter family receptor
BCM0045_0875	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BCM0045_0882	COG4978	Transcriptional regulator
BCM0045_0882	COG0789	Transcriptional regulator
BCM0045_0890	COG0305	Participates in initiation and elongation during chromosome replication
BCM0045_0899	COG0477	Major facilitator Superfamily
BCM0045_0906	COG2801	Transposase and inactivated derivatives
BCM0045_0907	COG2801	Transposase and inactivated derivatives
BCM0045_0916	COG1404	Belongs to the peptidase S8 family
BCM0045_0930	COG3711	transcriptional antiterminator
BCM0045_0931	COG2190	(PTS) system
BCM0045_0931	COG1263	PTS System
BCM0045_0931	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_0932	COG2723	6-phospho-beta-galactosidase activity
BCM0045_0937	COG0367	asparagine synthase
BCM0045_0940	COG1132	(ABC) transporter
BCM0045_0942	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCM0045_0942	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCM0045_0954	COG1136	(ABC) transporter
BCM0045_0954	COG0577	efflux transmembrane transporter activity
BCM0045_0960	COG1183	phosphatidylcholine synthase activity
BCM0045_0963	COG2376	Dihydroxyacetone kinase
BCM0045_0965	COG2376	Dihydroxyacetone kinase
BCM0045_0984	COG3237	CsbD-like
BCM0045_0989	COG1191	sigma factor activity
BCM0045_0991	COG2208	phosphoserine phosphatase activity
BCM0045_0992	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCM0045_0993	COG0784	Response regulator, receiver
BCM0045_0993	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_0993	COG2198	Histidine kinase
BCM0045_0993	COG2205	protein histidine kinase activity
BCM0045_1000	COG0745	RESPONSE REGULATOR receiver
BCM0045_1001	COG2205	protein histidine kinase activity
BCM0045_1009	COG0420	3'-5' exonuclease activity
BCM0045_1010	COG4717	serine-type aminopeptidase activity
BCM0045_1013	COG0346	lactoylglutathione lyase activity
BCM0045_1014	COG0346	lactoylglutathione lyase activity
BCM0045_1015	COG0457	Tetratricopeptide repeat
BCM0045_1017	COG2267	carboxylic ester hydrolase activity
BCM0045_1023	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCM0045_1024	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCM0045_1026	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCM0045_1027	COG2963	transposase activity
BCM0045_1028	COG2801	Transposase and inactivated derivatives
BCM0045_1037	COG0477	Major facilitator Superfamily
BCM0045_1038	COG0477	Major facilitator Superfamily
BCM0045_1040	COG3973	AAA domain
BCM0045_1041	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0045_1045	COG4980	gas vesicle protein
BCM0045_1046	COG0537	adenosine 5'-monophosphoramidase activity
BCM0045_1047	COG1131	(ABC) transporter
BCM0045_1048	COG4473	ABC transporter
BCM0045_1051	COG1309	transcriptional regulator
BCM0045_1053	COG3402	PFAM membrane-flanked domain
BCM0045_1054	COG3428	Bacterial PH domain
BCM0045_1061	COG3402	PFAM membrane-flanked domain
BCM0045_1062	COG3428	Bacterial PH domain
BCM0045_1063	COG2329	Antibiotic biosynthesis monooxygenase
BCM0045_1064	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0045_1067	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCM0045_1072	COG1309	transcriptional regulator
BCM0045_1073	COG1511	domain protein
BCM0045_1079	COG2378	regulation of single-species biofilm formation
BCM0045_1080	COG1609	Transcriptional regulator
BCM0045_1082	COG1234	tRNA 3'-trailer cleavage
BCM0045_1083	COG0095	Lipoate-protein ligase
BCM0045_1084	COG3328	transposase activity
BCM0045_1085	COG2205	protein histidine kinase activity
BCM0045_1086	COG0745	RESPONSE REGULATOR receiver
BCM0045_1091	COG0501	Belongs to the peptidase M48B family
BCM0045_1092	COG0697	spore germination
BCM0045_1096	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCM0045_1097	COG2224	Isocitrate lyase
BCM0045_1099	COG1278	Cold shock
BCM0045_1102	COG4903	ComK protein
BCM0045_1104	COG4585	Histidine kinase
BCM0045_1105	COG2197	response regulator
BCM0045_1108	COG0398	Pfam SNARE associated Golgi protein
BCM0045_1123	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCM0045_1128	COG0367	asparagine synthase
BCM0045_1129	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCM0045_1130	COG0753	catalase activity
BCM0045_1132	COG0004	ammonium transporteR
BCM0045_1138	COG2996	Protein conserved in bacteria
BCM0045_1139	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0045_1141	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_1144	COG0561	phosphatase activity
BCM0045_1146	COG0542	response to heat
BCM0045_1148	COG2267	carboxylic ester hydrolase activity
BCM0045_1151	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0045_1152	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCM0045_1153	COG5504	Zn-dependent protease
BCM0045_1155	COG0180	Tryptophanyl-tRNA synthetase
BCM0045_1156	COG4166	transmembrane transport
BCM0045_1157	COG0601	transmembrane transport
BCM0045_1158	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0045_1159	COG0444	Belongs to the ABC transporter superfamily
BCM0045_1160	COG4608	Belongs to the ABC transporter superfamily
BCM0045_1161	COG0534	Mate efflux family protein
BCM0045_1162	COG4166	transmembrane transport
BCM0045_1166	COG0861	Integral membrane protein TerC family
BCM0045_1167	COG4862	establishment of competence for transformation
BCM0045_1168	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0045_1170	COG1164	Oligoendopeptidase f
BCM0045_1173	COG2346	COG2346, Truncated hemoglobins
BCM0045_1174	COG4116	CYTH
BCM0045_1176	COG2357	RelA SpoT domain protein
BCM0045_1178	COG0564	pseudouridine synthase activity
BCM0045_1181	COG0772	Belongs to the SEDS family
BCM0045_1182	COG1216	Glycosyl transferase, family 2
BCM0045_1186	COG0457	Tetratricopeptide repeat
BCM0045_1186	COG0463	Glycosyl transferase, family 2
BCM0045_1190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCM0045_1193	COG1091	dTDP-4-dehydrorhamnose reductase activity
BCM0045_1202	COG2153	protein acetylation
BCM0045_1204	COG2382	esterase
BCM0045_1207	COG5492	domain, Protein
BCM0045_1208	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0045_1210	COG0512	Glutamine amidotransferase of anthranilate synthase
BCM0045_1210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCM0045_1217	COG1620	l-lactate permease
BCM0045_1218	COG5634	Uncharacterized conserved protein (DUF2278)
BCM0045_1231	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0045_1233	COG1476	TRANSCRIPTIONal
BCM0045_1241	COG2226	methyltransferase
BCM0045_1243	COG1686	Belongs to the peptidase S11 family
BCM0045_1244	COG0681	Belongs to the peptidase S26 family
BCM0045_1248	COG1396	sequence-specific DNA binding
BCM0045_1251	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_1253	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCM0045_1254	COG1177	transmembrane transport
BCM0045_1255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCM0045_1257	COG2409	Drug exporters of the RND superfamily
BCM0045_1259	COG0564	pseudouridine synthase activity
BCM0045_1261	COG2340	Cysteine-rich secretory protein family
BCM0045_1262	COG0247	lactate metabolic process
BCM0045_1263	COG0277	FAD linked oxidase domain protein
BCM0045_1264	COG3835	regulator
BCM0045_1266	COG0745	RESPONSE REGULATOR receiver
BCM0045_1267	COG5002	protein histidine kinase activity
BCM0045_1268	COG2186	Transcriptional regulator
BCM0045_1272	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCM0045_1274	COG2116	formate transmembrane transporter activity
BCM0045_1275	COG0861	Integral membrane protein TerC family
BCM0045_1276	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0045_1278	COG2030	dehydratase
BCM0045_1282	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_1283	COG3243	poly(R)-hydroxyalkanoic acid synthase
BCM0045_1284	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0045_1285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0045_1289	COG1840	ABC-type Fe3 transport system, periplasmic component
BCM0045_1290	COG3842	ATPase activity
BCM0045_1295	COG1349	DNA-binding transcription factor activity
BCM0045_1298	COG0235	Class ii aldolase
BCM0045_1300	COG2861	carbohydrate metabolic process
BCM0045_1302	COG3852	Histidine kinase
BCM0045_1303	COG1846	Transcriptional regulator
BCM0045_1305	COG2318	DinB family
BCM0045_1306	COG5002	protein histidine kinase activity
BCM0045_1308	COG0720	synthase
BCM0045_1311	COG4873	Protein conserved in bacteria
BCM0045_1317	COG1780	Probably involved in ribonucleotide reductase function
BCM0045_1318	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0045_1319	COG1403	HNH endonuclease
BCM0045_1320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0045_1320	COG1372	Participates in initiation and elongation during chromosome replication
BCM0045_1321	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0045_1322	COG1725	Transcriptional regulator
BCM0045_1323	COG1131	(ABC) transporter
BCM0045_1325	COG1131	(ABC) transporter
BCM0045_1326	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0045_1329	COG1522	sequence-specific DNA binding
BCM0045_1331	COG1335	isochorismatase
BCM0045_1333	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0045_1334	COG2070	2-Nitropropane dioxygenase
BCM0045_1335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCM0045_1337	COG1696	Membrane protein involved in D-alanine export
BCM0045_1342	COG0716	FMN binding
BCM0045_1345	COG3173	Aminoglycoside phosphotransferase
BCM0045_1349	COG0534	Mate efflux family protein
BCM0045_1350	COG1968	undecaprenyl-diphosphatase activity
BCM0045_1353	COG1846	Transcriptional regulator
BCM0045_1355	COG1301	dicarboxylic acid transport
BCM0045_1356	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0045_1357	COG4709	membrane
BCM0045_1358	COG3874	Sporulation protein YtfJ
BCM0045_1362	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0045_1363	COG0028	Belongs to the TPP enzyme family
BCM0045_1364	COG0440	acetolactate synthase activity
BCM0045_1379	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCM0045_1382	COG1183	phosphatidylcholine synthase activity
BCM0045_1383	COG1368	sulfuric ester hydrolase activity
BCM0045_1385	COG0019	diaminopimelate decarboxylase activity
BCM0045_1389	COG0529	Catalyzes the synthesis of activated sulfate
BCM0045_1390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCM0045_1394	COG1648	precorrin-2 dehydrogenase activity
BCM0045_1395	COG0733	neurotransmitter:sodium symporter activity
BCM0045_1399	COG1757	Na H antiporter
BCM0045_1402	COG4758	membrane
BCM0045_1403	COG4585	Histidine kinase
BCM0045_1404	COG2197	response regulator
BCM0045_1406	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_1408	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCM0045_1416	COG0730	response to heat
BCM0045_1417	COG0306	phosphate transporter
BCM0045_1418	COG1392	Phosphate transport regulator
BCM0045_1419	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0045_1422	COG3852	Histidine kinase
BCM0045_1423	COG1801	Protein of unknown function DUF72
BCM0045_1425	COG2801	Transposase and inactivated derivatives
BCM0045_1427	COG0582	viral genome integration into host DNA
BCM0045_1428	COG5002	protein histidine kinase activity
BCM0045_1432	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCM0045_1432	COG0392	lysyltransferase activity
BCM0045_1435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0045_1436	COG1686	Belongs to the peptidase S11 family
BCM0045_1437	COG2715	membrane protein required for spore maturation
BCM0045_1438	COG0700	Nucleoside recognition
BCM0045_1439	COG1187	pseudouridine synthase activity
BCM0045_1441	COG1333	cytochrome c biogenesis protein
BCM0045_1442	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCM0045_1443	COG0745	RESPONSE REGULATOR receiver
BCM0045_1444	COG5002	protein histidine kinase activity
BCM0045_1445	COG2096	Adenosyltransferase
BCM0045_1446	COG4942	peptidase
BCM0045_1448	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCM0045_1449	COG1141	Ferredoxin
BCM0045_1451	COG0514	ATP-dependent DNA helicase (RecQ)
BCM0045_1452	COG1266	CAAX protease self-immunity
BCM0045_1454	COG1408	metallophosphoesterase
BCM0045_1456	COG4862	establishment of competence for transformation
BCM0045_1457	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCM0045_1461	COG0492	ferredoxin-NADP+ reductase activity
BCM0045_1476	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0045_1479	COG0142	geranyltranstransferase activity
BCM0045_1481	COG0142	geranyltranstransferase activity
BCM0045_1486	COG0457	Tetratricopeptide repeat
BCM0045_1490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCM0045_1492	COG4347	Protein of unknown function (DUF1405)
BCM0045_1495	COG2738	Putative neutral zinc metallopeptidase
BCM0045_1497	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_1498	COG1694	Mazg nucleotide pyrophosphohydrolase
BCM0045_1501	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCM0045_1502	COG0438	transferase activity, transferring glycosyl groups
BCM0045_1510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCM0045_1510	COG1199	ATP-dependent helicase activity
BCM0045_1514	COG3935	DnaD domain protein
BCM0045_1515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCM0045_1517	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0045_1517	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCM0045_1528	COG0116	Belongs to the methyltransferase superfamily
BCM0045_1530	COG1199	ATP-dependent helicase activity
BCM0045_1531	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCM0045_1533	COG3173	Aminoglycoside phosphotransferase
BCM0045_1534	COG0024	Methionine aminopeptidase
BCM0045_1536	COG2233	PERMEase
BCM0045_1537	COG2311	Membrane
BCM0045_1539	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0045_1541	COG0456	acetyltransferase
BCM0045_1547	COG0754	glutathionylspermidine amidase activity
BCM0045_1550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0045_1553	COG0454	-acetyltransferase
BCM0045_1557	COG0328	RNA-DNA hybrid ribonuclease activity
BCM0045_1564	COG3403	YqcI/YcgG family
BCM0045_1565	COG1280	lysine exporter protein (LysE YggA)
BCM0045_1568	COG3162	membrane
BCM0045_1569	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0045_1570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0045_1572	COG0475	glutathione-regulated potassium exporter activity
BCM0045_1573	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0045_1574	COG4978	Transcriptional regulator
BCM0045_1574	COG0789	Transcriptional regulator
BCM0045_1576	COG2323	membrane
BCM0045_1577	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCM0045_1584	COG2814	Major facilitator Superfamily
BCM0045_1590	COG1923	regulation of RNA biosynthetic process
BCM0045_1592	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCM0045_1593	COG1360	Flagellar Motor Protein
BCM0045_1594	COG2201	protein-glutamate methylesterase activity
BCM0045_1595	COG0643	Histidine kinase
BCM0045_1595	COG2198	Histidine kinase
BCM0045_1596	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0045_1596	COG1776	CheC inhibitor of MCP methylation
BCM0045_1599	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCM0045_1603	COG1256	bacterial-type flagellum assembly
BCM0045_1604	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCM0045_1605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCM0045_1608	COG1815	bacterial-type flagellum-dependent cell motility
BCM0045_1609	COG1558	bacterial-type flagellum-dependent cell motility
BCM0045_1611	COG1766	The M ring may be actively involved in energy transduction
BCM0045_1612	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0045_1614	COG1157	protein secretion by the type III secretion system
BCM0045_1621	COG0784	Response regulator, receiver
BCM0045_1621	COG0835	chemotaxis
BCM0045_1623	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCM0045_1625	COG0741	lytic transglycosylase activity
BCM0045_1627	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0045_1628	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0045_1628	COG1776	CheC inhibitor of MCP methylation
BCM0045_1630	COG1338	Plays a role in the flagellum-specific transport system
BCM0045_1631	COG1987	bacterial-type flagellum assembly
BCM0045_1633	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCM0045_1634	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCM0045_1635	COG1419	protein localization to endoplasmic reticulum
BCM0045_1636	COG4786	Flagellar basal body rod
BCM0045_1637	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCM0045_1642	COG1309	transcriptional regulator
BCM0045_1645	COG2329	Antibiotic biosynthesis monooxygenase
BCM0045_1648	COG3764	Sortase (surface protein transpeptidase)
BCM0045_1649	COG3764	Sortase (surface protein transpeptidase)
BCM0045_1654	COG0583	DNA-binding transcription factor activity
BCM0045_1655	COG3842	ATPase activity
BCM0045_1656	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCM0045_1658	COG1234	tRNA 3'-trailer cleavage
BCM0045_1661	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_1665	COG0406	alpha-ribazole phosphatase activity
BCM0045_1669	COG1846	Transcriptional regulator
BCM0045_1671	COG0367	asparagine synthase
BCM0045_1677	COG1802	Transcriptional regulator
BCM0045_1678	COG0697	spore germination
BCM0045_1679	COG0523	cobalamin synthesis protein
BCM0045_1681	COG0701	Predicted permease
BCM0045_1684	COG1757	Na H antiporter
BCM0045_1685	COG0114	fumarate hydratase activity
BCM0045_1690	COG0534	Mate efflux family protein
BCM0045_1691	COG3340	Belongs to the peptidase S51 family
BCM0045_1695	COG0785	Cytochrome C biogenesis protein
BCM0045_1702	COG2733	membrane
BCM0045_1709	COG1131	(ABC) transporter
BCM0045_1712	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0045_1717	COG0528	UMP kinase activity
BCM0045_1719	COG1027	Aspartate ammonia-lyase
BCM0045_1720	COG0281	malic enzyme
BCM0045_1721	COG4191	Histidine kinase
BCM0045_1722	COG0784	Response regulator, receiver
BCM0045_1724	COG1361	Conserved repeat domain
BCM0045_1734	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0045_1744	COG2814	Major facilitator Superfamily
BCM0045_1747	COG1966	Carbon starvation protein
BCM0045_1749	COG1695	Transcriptional regulator
BCM0045_1751	COG0477	Major facilitator Superfamily
BCM0045_1752	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0045_1753	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCM0045_1754	COG4166	transmembrane transport
BCM0045_1755	COG2223	nitrite transmembrane transporter activity
BCM0045_1756	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0045_1759	COG2244	polysaccharide biosynthetic process
BCM0045_1760	COG0733	neurotransmitter:sodium symporter activity
BCM0045_1762	COG5566	PFAM Mor transcription activator
BCM0045_1764	COG2323	membrane
BCM0045_1766	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0045_1768	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0045_1769	COG0028	Belongs to the TPP enzyme family
BCM0045_1771	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCM0045_1773	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCM0045_1778	COG2814	Major facilitator Superfamily
BCM0045_1779	COG3384	dioxygenase
BCM0045_1781	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCM0045_1783	COG0427	acetyl-CoA hydrolase
BCM0045_1787	COG1073	alpha beta
BCM0045_1788	COG4166	transmembrane transport
BCM0045_1793	COG0535	radical SAM domain protein
BCM0045_1794	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_1799	COG1914	H( )-stimulated, divalent metal cation uptake system
BCM0045_1802	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCM0045_1804	COG0531	amino acid
BCM0045_1810	COG0714	Associated with various cellular activities
BCM0045_1812	COG3552	Protein containing von Willebrand factor type A (VWA) domain
BCM0045_1817	COG2390	Transcriptional regulator
BCM0045_1819	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_1820	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCM0045_1822	COG4846	Membrane protein involved in cytochrome C biogenesis
BCM0045_1826	COG0006	proline dipeptidase activity
BCM0045_1827	COG2132	Multicopper oxidase
BCM0045_1830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCM0045_1836	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_1838	COG2372	response to copper ion
BCM0045_1838	COG1276	copper resistance
BCM0045_1839	COG4549	nuclear export factor GLE1
BCM0045_1841	COG0697	spore germination
BCM0045_1842	COG0583	DNA-binding transcription factor activity
BCM0045_1843	COG1959	2 iron, 2 sulfur cluster binding
BCM0045_1844	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCM0045_1845	COG0778	Nitroreductase
BCM0045_1848	COG0628	permease
BCM0045_1850	COG1231	oxidoreductase activity
BCM0045_1851	COG0523	cobalamin synthesis protein
BCM0045_1853	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0045_1854	COG2030	dehydratase
BCM0045_1855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0045_1857	COG0411	ABC transporter
BCM0045_1861	COG0583	DNA-binding transcription factor activity
BCM0045_1867	COG1271	oxidase subunit
BCM0045_1868	COG1294	oxidase, subunit
BCM0045_1869	COG4988	ABC transporter
BCM0045_1870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCM0045_1874	COG1686	Belongs to the peptidase S11 family
BCM0045_1877	COG0791	NLP P60 protein
BCM0045_1877	COG1388	LysM domain
BCM0045_1879	COG1132	(ABC) transporter
BCM0045_1880	COG0745	RESPONSE REGULATOR receiver
BCM0045_1881	COG5002	protein histidine kinase activity
BCM0045_1882	COG2205	protein histidine kinase activity
BCM0045_1883	COG0745	RESPONSE REGULATOR receiver
BCM0045_1888	COG0300	oxidoreductase activity
BCM0045_1889	COG4122	O-methyltransferase activity
BCM0045_1892	COG5658	integral membrane protein
BCM0045_1896	COG0460	homoserine dehydrogenase
BCM0045_1901	COG1316	TRANSCRIPTIONal
BCM0045_1903	COG0745	RESPONSE REGULATOR receiver
BCM0045_1904	COG5002	protein histidine kinase activity
BCM0045_1907	COG1285	pathogenesis
BCM0045_1908	COG1247	-acetyltransferase
BCM0045_1912	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0045_1914	COG1082	Xylose isomerase domain protein TIM barrel
BCM0045_1916	COG2814	Major facilitator Superfamily
BCM0045_1917	COG1279	arginine transmembrane transporter activity
BCM0045_1919	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCM0045_1926	COG0577	efflux transmembrane transporter activity
BCM0045_1927	COG2002	toxin-antitoxin pair type II binding
BCM0045_1928	COG1404	Belongs to the peptidase S8 family
BCM0045_1929	COG0640	Transcriptional regulator
BCM0045_1930	COG0667	Aldo Keto reductase
BCM0045_1931	COG2814	Major facilitator Superfamily
BCM0045_1936	COG0840	transmembrane signaling receptor activity
BCM0045_1939	COG3949	Membrane
BCM0045_1940	COG0783	Belongs to the Dps family
BCM0045_1943	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCM0045_1945	COG1231	oxidoreductase activity
BCM0045_1947	COG4989	oxidoreductase activity
BCM0045_1948	COG0523	cobalamin synthesis protein
BCM0045_1949	COG0456	acetyltransferase
BCM0045_1950	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCM0045_1950	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCM0045_1952	COG0702	epimerase
BCM0045_1954	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCM0045_1956	COG4166	transmembrane transport
BCM0045_1959	COG0406	alpha-ribazole phosphatase activity
BCM0045_1961	COG5337	Spore coat protein CotH
BCM0045_1962	COG1051	belongs to the nudix hydrolase family
BCM0045_1963	COG0586	Pfam SNARE associated Golgi protein
BCM0045_1964	COG2244	polysaccharide biosynthetic process
BCM0045_1966	COG0701	Predicted permease
BCM0045_1967	COG3689	TIGRFAM TIGR03943 family protein
BCM0045_1968	COG1607	acyl-coa hydrolase
BCM0045_1969	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0045_1972	COG0702	epimerase
BCM0045_1973	COG2839	Protein conserved in bacteria
BCM0045_1974	COG1253	flavin adenine dinucleotide binding
BCM0045_1977	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_1978	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0045_1981	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0045_1983	COG1876	peptidase activity
BCM0045_1985	COG0154	amidase activity
BCM0045_1986	COG2211	Major facilitator Superfamily
BCM0045_1990	COG2368	4-hydroxyphenylacetate
BCM0045_1992	COG0196	riboflavin kinase activity
BCM0045_1995	COG0251	oxidation-reduction process
BCM0045_1997	COG3971	2-oxopent-4-enoate hydratase activity
BCM0045_2001	COG1942	4-Oxalocrotonate Tautomerase
BCM0045_2003	COG0561	phosphatase activity
BCM0045_2006	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCM0045_2007	COG4106	trans-aconitate 2-methyltransferase activity
BCM0045_2010	COG1819	glycosyl
BCM0045_2011	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_2012	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2017	COG0456	acetyltransferase
BCM0045_2026	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCM0045_2046	COG3874	Sporulation protein YtfJ
BCM0045_2051	COG2226	methyltransferase
BCM0045_2055	COG1082	Xylose isomerase domain protein TIM barrel
BCM0045_2056	COG0346	lactoylglutathione lyase activity
BCM0045_2058	COG0604	alcohol dehydrogenase
BCM0045_2059	COG1595	DNA-templated transcription, initiation
BCM0045_2065	COG0386	Belongs to the glutathione peroxidase family
BCM0045_2066	COG1305	Transglutaminase-like
BCM0045_2068	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BCM0045_2069	COG0714	Associated with various cellular activities
BCM0045_2073	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCM0045_2074	COG1140	nitrate reductase beta subunit
BCM0045_2075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCM0045_2076	COG2181	nitrate reductase activity
BCM0045_2077	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCM0045_2078	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCM0045_2079	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0045_2080	COG0303	'Molybdopterin
BCM0045_2081	COG0314	molybdopterin synthase activity
BCM0045_2083	COG2223	nitrite transmembrane transporter activity
BCM0045_2085	COG1648	precorrin-2 dehydrogenase activity
BCM0045_2087	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCM0045_2087	COG1587	Uroporphyrinogen-III synthase
BCM0045_2088	COG2146	nitrite reductase [NAD(P)H] activity
BCM0045_2089	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCM0045_2090	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BCM0045_2097	COG2359	stage V sporulation protein S
BCM0045_2098	COG2801	Transposase and inactivated derivatives
BCM0045_2103	COG1418	mRNA catabolic process
BCM0045_2104	COG0488	(ABC) transporter
BCM0045_2107	COG0629	single-stranded DNA binding
BCM0045_2110	COG1413	lyase activity
BCM0045_2113	COG2521	methyltransferase
BCM0045_2113	COG2136	Putative SAM-dependent methyltransferase
BCM0045_2118	COG3328	transposase activity
BCM0045_2124	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCM0045_2125	COG0017	Asparaginyl-tRNA synthetase
BCM0045_2126	COG1929	Belongs to the glycerate kinase type-1 family
BCM0045_2127	COG0471	metal ion transport
BCM0045_2128	COG0745	RESPONSE REGULATOR receiver
BCM0045_2129	COG5002	protein histidine kinase activity
BCM0045_2129	COG3850	Histidine kinase
BCM0045_2132	COG0733	neurotransmitter:sodium symporter activity
BCM0045_2137	COG2610	gluconate transmembrane transporter activity
BCM0045_2138	COG1454	alcohol dehydrogenase
BCM0045_2139	COG1794	racemase activity, acting on amino acids and derivatives
BCM0045_2141	COG0456	acetyltransferase
BCM0045_2142	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCM0045_2144	COG1131	(ABC) transporter
BCM0045_2145	COG4473	ABC transporter
BCM0045_2147	COG0546	phosphoglycolate phosphatase activity
BCM0045_2151	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0045_2152	COG3250	beta-galactosidase activity
BCM0045_2155	COG0768	penicillin binding
BCM0045_2157	COG0204	Acyl-transferase
BCM0045_2158	COG1272	protein, Hemolysin III
BCM0045_2160	COG0805	protein transport
BCM0045_2162	COG1307	EDD domain protein, DegV family
BCM0045_2164	COG2801	Transposase and inactivated derivatives
BCM0045_2165	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCM0045_2166	COG1999	signal sequence binding
BCM0045_2167	COG0071	Belongs to the small heat shock protein (HSP20) family
BCM0045_2168	COG0367	asparagine synthase
BCM0045_2171	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_2172	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0045_2176	COG1335	isochorismatase
BCM0045_2177	COG0071	Belongs to the small heat shock protein (HSP20) family
BCM0045_2178	COG0668	transmembrane transport
BCM0045_2179	COG2203	Gaf domain
BCM0045_2179	COG4585	Histidine kinase
BCM0045_2180	COG2197	response regulator
BCM0045_2182	COG1064	alcohol dehydrogenase
BCM0045_2194	COG0517	IMP dehydrogenase activity
BCM0045_2194	COG1125	glycine betaine transport
BCM0045_2195	COG1174	glycine betaine transport
BCM0045_2198	COG2801	Transposase and inactivated derivatives
BCM0045_2204	COG1253	flavin adenine dinucleotide binding
BCM0045_2205	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_2206	COG5506	Protein of unknown function (DUF1694)
BCM0045_2209	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0045_2210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BCM0045_2211	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCM0045_2212	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0045_2213	COG0456	acetyltransferase
BCM0045_2214	COG3829	transcription factor binding
BCM0045_2215	COG1509	lysine 2,3-aminomutase activity
BCM0045_2222	COG0515	serine threonine protein kinase
BCM0045_2222	COG4991	sh3 domain protein
BCM0045_2222	COG3064	Membrane
BCM0045_2223	COG4326	sporulation control protein
BCM0045_2224	COG0671	phosphoesterase, PA-phosphatase related
BCM0045_2229	COG0456	acetyltransferase
BCM0045_2229	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0045_2232	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCM0045_2233	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0045_2245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0045_2251	COG0300	oxidoreductase activity
BCM0045_2255	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCM0045_2255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0045_2257	COG4841	protein insertion into membrane
BCM0045_2258	COG0372	Belongs to the citrate synthase family
BCM0045_2259	COG2079	MmgE PrpD family protein
BCM0045_2260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCM0045_2261	COG1960	acyl-CoA dehydrogenase activity
BCM0045_2262	COG2084	Dehydrogenase
BCM0045_2264	COG1280	lysine exporter protein (LysE YggA)
BCM0045_2265	COG1024	Enoyl-CoA hydratase
BCM0045_2268	COG0420	3'-5' exonuclease activity
BCM0045_2274	COG2223	nitrite transmembrane transporter activity
BCM0045_2276	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_2277	COG1169	isochorismate synthase
BCM0045_2278	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCM0045_2279	COG1535	isochorismatase
BCM0045_2279	COG3433	isochorismatase activity
BCM0045_2280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCM0045_2281	COG3251	PFAM MbtH domain protein
BCM0045_2282	COG2814	Major facilitator Superfamily
BCM0045_2285	COG0776	regulation of translation
BCM0045_2287	COG2318	DinB family
BCM0045_2289	COG1115	amino acid carrier protein
BCM0045_2292	COG2329	Antibiotic biosynthesis monooxygenase
BCM0045_2293	COG1187	pseudouridine synthase activity
BCM0045_2294	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCM0045_2295	COG1136	(ABC) transporter
BCM0045_2297	COG0596	Alpha beta hydrolase
BCM0045_2299	COG2814	Major facilitator Superfamily
BCM0045_2312	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_2319	COG1247	-acetyltransferase
BCM0045_2325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCM0045_2327	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_2329	COG1278	Cold shock
BCM0045_2332	COG0010	Belongs to the arginase family
BCM0045_2334	COG1846	Transcriptional regulator
BCM0045_2335	COG2814	Major facilitator Superfamily
BCM0045_2336	COG0583	DNA-binding transcription factor activity
BCM0045_2337	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCM0045_2340	COG0583	DNA-binding transcription factor activity
BCM0045_2341	COG2258	MOSC domain
BCM0045_2345	COG1132	(ABC) transporter
BCM0045_2346	COG1132	(ABC) transporter
BCM0045_2350	COG1396	sequence-specific DNA binding
BCM0045_2356	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCM0045_2358	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BCM0045_2359	COG1595	DNA-templated transcription, initiation
BCM0045_2364	COG1649	PFAM Uncharacterised BCR, COG1649
BCM0045_2369	COG2971	BadF BadG BcrA BcrD
BCM0045_2371	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCM0045_2375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_2382	COG1309	transcriptional regulator
BCM0045_2385	COG1136	(ABC) transporter
BCM0045_2385	COG0577	efflux transmembrane transporter activity
BCM0045_2392	COG2801	Transposase and inactivated derivatives
BCM0045_2398	COG1846	Transcriptional regulator
BCM0045_2404	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCM0045_2406	COG0110	maltose O-acetyltransferase activity
BCM0045_2408	COG1686	Belongs to the peptidase S11 family
BCM0045_2410	COG0768	penicillin binding
BCM0045_2412	COG1595	DNA-templated transcription, initiation
BCM0045_2414	COG0768	penicillin binding
BCM0045_2415	COG0768	penicillin binding
BCM0045_2416	COG2367	Beta-lactamase
BCM0045_2417	COG1408	metallophosphoesterase
BCM0045_2419	COG1131	(ABC) transporter
BCM0045_2421	COG1309	transcriptional regulator
BCM0045_2424	COG1960	acyl-CoA dehydrogenase activity
BCM0045_2425	COG0439	Biotin carboxylase
BCM0045_2426	COG0511	ligase activity, forming carbon-carbon bonds
BCM0045_2427	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCM0045_2428	COG1024	Enoyl-CoA hydratase
BCM0045_2429	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCM0045_2430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0045_2432	COG1247	-acetyltransferase
BCM0045_2433	COG0572	uridine kinase
BCM0045_2434	COG1686	Belongs to the peptidase S11 family
BCM0045_2440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCM0045_2444	COG3227	Zinc metalloprotease (Elastase)
BCM0045_2447	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCM0045_2453	COG2814	Major facilitator Superfamily
BCM0045_2455	COG2226	methyltransferase
BCM0045_2462	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2472	COG3386	PFAM SMP-30 Gluconolaconase
BCM0045_2474	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BCM0045_2475	COG3773	Cell wall hydrolase
BCM0045_2477	COG0745	RESPONSE REGULATOR receiver
BCM0045_2478	COG2205	protein histidine kinase activity
BCM0045_2480	COG0488	(ABC) transporter
BCM0045_2482	COG1136	(ABC) transporter
BCM0045_2483	COG0577	efflux transmembrane transporter activity
BCM0045_2488	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCM0045_2513	COG2124	cytochrome p450
BCM0045_2521	COG0561	phosphatase activity
BCM0045_2522	COG5002	protein histidine kinase activity
BCM0045_2523	COG0768	penicillin binding
BCM0045_2525	COG1819	glycosyl
BCM0045_2526	COG1794	racemase activity, acting on amino acids and derivatives
BCM0045_2530	COG2205	protein histidine kinase activity
BCM0045_2532	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0045_2533	COG0604	alcohol dehydrogenase
BCM0045_2534	COG0671	phosphoesterase, PA-phosphatase related
BCM0045_2535	COG0768	penicillin binding
BCM0045_2537	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_2539	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0045_2546	COG0693	protein deglycase activity
BCM0045_2552	COG2814	Major facilitator Superfamily
BCM0045_2555	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0045_2559	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2560	COG0697	spore germination
BCM0045_2564	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0045_2566	COG2223	nitrite transmembrane transporter activity
BCM0045_2569	COG2816	NAD+ diphosphatase activity
BCM0045_2570	COG0592	DNA-directed DNA polymerase activity
BCM0045_2571	COG1051	belongs to the nudix hydrolase family
BCM0045_2577	COG3878	Protein conserved in bacteria
BCM0045_2582	COG4667	esterase of the alpha-beta hydrolase superfamily
BCM0045_2587	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCM0045_2590	COG0322	excinuclease ABC activity
BCM0045_2599	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0045_2604	COG1011	Hydrolase
BCM0045_2608	COG1523	belongs to the glycosyl hydrolase 13 family
BCM0045_2609	COG3227	Zinc metalloprotease (Elastase)
BCM0045_2613	COG0201	protein transport
BCM0045_2615	COG0697	spore germination
BCM0045_2616	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2623	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_2626	COG2959	enzyme of heme biosynthesis
BCM0045_2632	COG3844	kynureninase activity
BCM0045_2633	COG1309	transcriptional regulator
BCM0045_2639	COG3284	Transcriptional regulator
BCM0045_2643	COG1349	DNA-binding transcription factor activity
BCM0045_2645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCM0045_2646	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0045_2647	COG0022	dehydrogenase e1 component
BCM0045_2648	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0045_2650	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_2654	COG1051	belongs to the nudix hydrolase family
BCM0045_2658	COG4176	ABC-type proline glycine betaine transport system permease component
BCM0045_2659	COG0517	IMP dehydrogenase activity
BCM0045_2659	COG4175	Glycine betaine
BCM0045_2664	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BCM0045_2665	COG2153	protein acetylation
BCM0045_2666	COG3397	chitin binding
BCM0045_2670	COG2205	protein histidine kinase activity
BCM0045_2671	COG2226	methyltransferase
BCM0045_2672	COG2315	Protein conserved in bacteria
BCM0045_2673	COG2153	protein acetylation
BCM0045_2674	COG2333	competence protein COMEC
BCM0045_2674	COG0658	competence protein
BCM0045_2684	COG3973	AAA domain
BCM0045_2688	COG0514	ATP-dependent DNA helicase (RecQ)
BCM0045_2693	COG4637	Psort location Cytoplasmic, score
BCM0045_2698	COG3397	chitin binding
BCM0045_2700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCM0045_2701	COG1115	amino acid carrier protein
BCM0045_2702	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_2703	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCM0045_2705	COG3938	Belongs to the proline racemase family
BCM0045_2706	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0045_2714	COG0586	Pfam SNARE associated Golgi protein
BCM0045_2717	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCM0045_2718	COG0519	Catalyzes the synthesis of GMP from XMP
BCM0045_2719	COG4166	transmembrane transport
BCM0045_2721	COG4948	Mandelate Racemase Muconate Lactonizing
BCM0045_2728	COG2936	dipeptidyl-peptidase activity
BCM0045_2729	COG5002	protein histidine kinase activity
BCM0045_2730	COG0745	RESPONSE REGULATOR receiver
BCM0045_2737	COG1164	Oligoendopeptidase f
BCM0045_2738	COG0531	amino acid
BCM0045_2739	COG1522	sequence-specific DNA binding
BCM0045_2740	COG1307	EDD domain protein, DegV family
BCM0045_2743	COG2801	Transposase and inactivated derivatives
BCM0045_2751	COG2814	Major facilitator Superfamily
BCM0045_2753	COG1664	Polymer-forming cytoskeletal
BCM0045_2754	COG0789	Transcriptional regulator
BCM0045_2755	COG4533	DNA binding
BCM0045_2756	COG0477	Major facilitator Superfamily
BCM0045_2756	COG2814	Major facilitator Superfamily
BCM0045_2760	COG2261	transglycosylase associated protein
BCM0045_2763	COG2226	methyltransferase
BCM0045_2769	COG0436	Aminotransferase
BCM0045_2770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCM0045_2771	COG5146	pantothenate kinase activity
BCM0045_2772	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCM0045_2775	COG1131	(ABC) transporter
BCM0045_2785	COG0628	permease
BCM0045_2787	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCM0045_2788	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0045_2789	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0045_2792	COG2816	NAD+ diphosphatase activity
BCM0045_2796	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCM0045_2801	COG0697	spore germination
BCM0045_2802	COG2318	DinB family
BCM0045_2803	COG0454	-acetyltransferase
BCM0045_2806	COG4912	Dna alkylation repair
BCM0045_2810	COG0861	Integral membrane protein TerC family
BCM0045_2811	COG1368	sulfuric ester hydrolase activity
BCM0045_2812	COG0488	(ABC) transporter
BCM0045_2814	COG2409	Drug exporters of the RND superfamily
BCM0045_2814	COG1033	growth of symbiont in host cell
BCM0045_2815	COG1309	transcriptional regulator
BCM0045_2819	COG0287	Prephenate dehydrogenase
BCM0045_2820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCM0045_2822	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCM0045_2822	COG1605	Chorismate mutase
BCM0045_2829	COG1388	LysM domain
BCM0045_2829	COG3584	3D domain protein
BCM0045_2831	COG1595	DNA-templated transcription, initiation
BCM0045_2836	COG1879	ABC-type sugar transport system periplasmic component
BCM0045_2838	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCM0045_2849	COG2390	Transcriptional regulator
BCM0045_2850	COG1070	Carbohydrate kinase
BCM0045_2856	COG2329	Antibiotic biosynthesis monooxygenase
BCM0045_2860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_2863	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0045_2864	COG4187	Peptidase family M20/M25/M40
BCM0045_2865	COG1414	Transcriptional regulator
BCM0045_2866	COG0833	amino acid
BCM0045_2867	COG1690	Belongs to the RtcB family
BCM0045_2869	COG3239	Fatty acid desaturase
BCM0045_2870	COG1785	Belongs to the alkaline phosphatase family
BCM0045_2872	COG3655	Transcriptional regulator
BCM0045_2875	COG4377	Putative membrane peptidase family (DUF2324)
BCM0045_2877	COG3279	Response regulator of the LytR AlgR family
BCM0045_2879	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_2880	COG0346	lactoylglutathione lyase activity
BCM0045_2885	COG0714	Associated with various cellular activities
BCM0045_2889	COG0463	Glycosyl transferase, family 2
BCM0045_2894	COG0463	Glycosyl transferase, family 2
BCM0045_2896	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCM0045_2897	COG0753	catalase activity
BCM0045_2899	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BCM0045_2901	COG1280	lysine exporter protein (LysE YggA)
BCM0045_2906	COG0714	Associated with various cellular activities
BCM0045_2931	COG0778	Nitroreductase
BCM0045_2932	COG1846	Transcriptional regulator
BCM0045_2940	COG1725	Transcriptional regulator
BCM0045_2944	COG1136	(ABC) transporter
BCM0045_2944	COG0577	efflux transmembrane transporter activity
BCM0045_2949	COG2207	Transcriptional regulator
BCM0045_2950	COG0456	acetyltransferase
BCM0045_2953	COG0697	spore germination
BCM0045_2954	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_2963	COG0730	response to heat
BCM0045_2965	COG0833	amino acid
BCM0045_2967	COG4335	DNA alkylation repair
BCM0045_2974	COG0768	penicillin binding
BCM0045_2981	COG1984	allophanate hydrolase subunit 2
BCM0045_2982	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCM0045_2983	COG1414	Transcriptional regulator
BCM0045_2987	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0045_2988	COG0640	Transcriptional regulator
BCM0045_2990	COG1960	acyl-CoA dehydrogenase activity
BCM0045_2993	COG3314	Sporulation integral membrane protein YlbJ
BCM0045_2998	COG3848	Pyruvate phosphate dikinase
BCM0045_2998	COG0574	Belongs to the PEP-utilizing enzyme family
BCM0045_2999	COG1819	glycosyl
BCM0045_3000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_3004	COG5577	PFAM Coat F domain
BCM0045_3005	COG3403	YqcI/YcgG family
BCM0045_3006	COG1280	lysine exporter protein (LysE YggA)
BCM0045_3007	COG1113	amino acid transport
BCM0045_3013	COG1063	alcohol dehydrogenase
BCM0045_3020	COG4974	Belongs to the 'phage' integrase family
BCM0045_3022	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0045_3036	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0045_3037	COG0753	catalase activity
BCM0045_3038	COG0598	Magnesium transport protein CorA
BCM0045_3045	COG0415	Belongs to the DNA photolyase family
BCM0045_3046	COG0288	reversible hydration of carbon dioxide
BCM0045_3048	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCM0045_3049	COG5609	conserved protein (DUF2294)
BCM0045_3052	COG0714	Associated with various cellular activities
BCM0045_3053	COG1575	Belongs to the MenA family. Type 1 subfamily
BCM0045_3055	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCM0045_3056	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCM0045_3057	COG1121	(ABC) transporter
BCM0045_3060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_3062	COG0798	PFAM Bile acid sodium symporter
BCM0045_3063	COG0346	lactoylglutathione lyase activity
BCM0045_3064	COG0640	Transcriptional regulator
BCM0045_3066	COG0456	acetyltransferase
BCM0045_3067	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0045_3067	COG3320	Male sterility
BCM0045_3068	COG1309	transcriptional regulator
BCM0045_3069	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3070	COG1522	sequence-specific DNA binding
BCM0045_3073	COG0346	lactoylglutathione lyase activity
BCM0045_3080	COG2814	Major facilitator Superfamily
BCM0045_3085	COG0745	RESPONSE REGULATOR receiver
BCM0045_3086	COG3850	Histidine kinase
BCM0045_3086	COG5002	protein histidine kinase activity
BCM0045_3092	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BCM0045_3096	COG1476	TRANSCRIPTIONal
BCM0045_3101	COG0789	Transcriptional regulator
BCM0045_3102	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BCM0045_3105	COG1136	(ABC) transporter
BCM0045_3106	COG0577	efflux transmembrane transporter activity
BCM0045_3109	COG5002	protein histidine kinase activity
BCM0045_3109	COG3850	Histidine kinase
BCM0045_3111	COG2364	Membrane
BCM0045_3112	COG1846	Transcriptional regulator
BCM0045_3113	COG0456	acetyltransferase
BCM0045_3114	COG2808	Putative FMN-binding domain
BCM0045_3115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_3116	COG2271	Major facilitator Superfamily
BCM0045_3117	COG1556	Lactate utilization protein
BCM0045_3118	COG1139	Iron-sulfur cluster binding protein
BCM0045_3120	COG0583	DNA-binding transcription factor activity
BCM0045_3124	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0045_3127	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCM0045_3131	COG1595	DNA-templated transcription, initiation
BCM0045_3134	COG0662	Cupin 2, conserved barrel domain protein
BCM0045_3135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_3135	COG2207	Transcriptional regulator
BCM0045_3139	COG3409	Peptidoglycan-binding domain 1 protein
BCM0045_3139	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0045_3189	COG5444	nuclease activity
BCM0045_3197	COG2373	Large extracellular alpha-helical protein
BCM0045_3201	COG0477	Major facilitator Superfamily
BCM0045_3203	COG1846	Transcriptional regulator
BCM0045_3204	COG2814	Major facilitator Superfamily
BCM0045_3207	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0045_3208	COG1131	(ABC) transporter
BCM0045_3212	COG2076	Multidrug Resistance protein
BCM0045_3213	COG1309	transcriptional regulator
BCM0045_3216	COG1476	TRANSCRIPTIONal
BCM0045_3219	COG2031	fatty acid transporter
BCM0045_3221	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0045_3230	COG1122	ATPase activity
BCM0045_3232	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCM0045_3235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCM0045_3236	COG1288	antiporter activity
BCM0045_3238	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0045_3238	COG3409	Peptidoglycan-binding domain 1 protein
BCM0045_3240	COG3620	sequence-specific DNA binding
BCM0045_3243	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCM0045_3247	COG1733	regulation of RNA biosynthetic process
BCM0045_3248	COG0778	Nitroreductase
BCM0045_3252	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3254	COG1131	(ABC) transporter
BCM0045_3259	COG1011	Hydrolase
BCM0045_3261	COG2365	Tyrosine phosphatase family
BCM0045_3266	COG0346	lactoylglutathione lyase activity
BCM0045_3267	COG1940	carbohydrate kinase activity
BCM0045_3268	COG0110	maltose O-acetyltransferase activity
BCM0045_3270	COG1136	(ABC) transporter
BCM0045_3270	COG0577	efflux transmembrane transporter activity
BCM0045_3274	COG0628	permease
BCM0045_3278	COG2226	methyltransferase
BCM0045_3280	COG0477	Major facilitator Superfamily
BCM0045_3286	COG1253	flavin adenine dinucleotide binding
BCM0045_3287	COG0789	Transcriptional regulator
BCM0045_3289	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCM0045_3295	COG0697	spore germination
BCM0045_3296	COG1357	PFAM Pentapeptide repeats (8 copies)
BCM0045_3297	COG3813	Protein conserved in bacteria
BCM0045_3298	COG3328	transposase activity
BCM0045_3299	COG3328	transposase activity
BCM0045_3300	COG2706	6-phosphogluconolactonase activity
BCM0045_3301	COG1070	Carbohydrate kinase
BCM0045_3303	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCM0045_3304	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCM0045_3306	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCM0045_3308	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCM0045_3310	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3315	COG0656	L-ascorbic acid biosynthetic process
BCM0045_3319	COG0814	amino acid
BCM0045_3325	COG1393	Belongs to the ArsC family
BCM0045_3326	COG1733	regulation of RNA biosynthetic process
BCM0045_3327	COG2188	Transcriptional regulator
BCM0045_3328	COG0673	inositol 2-dehydrogenase activity
BCM0045_3329	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCM0045_3330	COG1733	regulation of RNA biosynthetic process
BCM0045_3331	COG1733	regulation of RNA biosynthetic process
BCM0045_3335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_3344	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0045_3345	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0045_3346	COG1733	regulation of RNA biosynthetic process
BCM0045_3352	COG1191	sigma factor activity
BCM0045_3357	COG1309	transcriptional regulator
BCM0045_3361	COG3152	Membrane
BCM0045_3366	COG1151	hydroxylamine reductase activity
BCM0045_3368	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_3369	COG3409	Peptidoglycan-binding domain 1 protein
BCM0045_3369	COG3757	hydrolase, family 25
BCM0045_3376	COG2072	flavoprotein involved in K transport
BCM0045_3384	COG1113	amino acid transport
BCM0045_3385	COG2814	Major facilitator Superfamily
BCM0045_3392	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCM0045_3393	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0045_3394	COG3328	transposase activity
BCM0045_3395	COG3328	transposase activity
BCM0045_3398	COG3739	integral membrane protein
BCM0045_3399	COG0384	phenazine biosynthesis protein PhzF
BCM0045_3405	COG0583	DNA-binding transcription factor activity
BCM0045_3409	COG1193	negative regulation of DNA recombination
BCM0045_3413	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCM0045_3414	COG1164	Oligoendopeptidase f
BCM0045_3416	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0045_3421	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0045_3425	COG0640	Transcriptional regulator
BCM0045_3426	COG0604	alcohol dehydrogenase
BCM0045_3428	COG0457	Tetratricopeptide repeat
BCM0045_3430	COG2808	Putative FMN-binding domain
BCM0045_3432	COG0456	acetyltransferase
BCM0045_3432	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0045_3434	COG0385	Bile acid
BCM0045_3435	COG0277	FAD linked oxidase domain protein
BCM0045_3441	COG1216	Glycosyl transferase, family 2
BCM0045_3442	COG1024	Enoyl-CoA hydratase
BCM0045_3444	COG1285	pathogenesis
BCM0045_3448	COG2514	catechol 2,3-dioxygenase activity
BCM0045_3449	COG2720	vancomycin resistance protein
BCM0045_3457	COG0716	FMN binding
BCM0045_3460	COG0494	nUDIX hydrolase
BCM0045_3464	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3466	COG0165	Argininosuccinate lyase
BCM0045_3469	COG4145	pantothenate transmembrane transporter activity
BCM0045_3471	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_3481	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_3482	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3484	COG1657	PFAM Prenyltransferase squalene oxidase
BCM0045_3485	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCM0045_3486	COG2962	Rard protein
BCM0045_3487	COG3326	Membrane
BCM0045_3490	COG0489	protein tyrosine kinase activity
BCM0045_3492	COG0314	molybdopterin synthase activity
BCM0045_3493	COG0303	'Molybdopterin
BCM0045_3494	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0045_3495	COG2116	formate transmembrane transporter activity
BCM0045_3497	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCM0045_3498	COG5609	conserved protein (DUF2294)
BCM0045_3499	COG2427	Protein of unknown function (DUF1641)
BCM0045_3500	COG3383	formate dehydrogenase (NAD+) activity
BCM0045_3502	COG0697	spore germination
BCM0045_3510	COG2226	methyltransferase
BCM0045_3511	COG4166	transmembrane transport
BCM0045_3513	COG2801	Transposase and inactivated derivatives
BCM0045_3514	COG4166	transmembrane transport
BCM0045_3515	COG4166	transmembrane transport
BCM0045_3516	COG1301	dicarboxylic acid transport
BCM0045_3517	COG1316	TRANSCRIPTIONal
BCM0045_3519	COG1595	DNA-templated transcription, initiation
BCM0045_3522	COG1131	(ABC) transporter
BCM0045_3527	COG0673	inositol 2-dehydrogenase activity
BCM0045_3528	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCM0045_3529	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCM0045_3530	COG0187	DNA topoisomerase II activity
BCM0045_3531	COG1832	CoA-binding protein
BCM0045_3532	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0045_3533	COG0745	RESPONSE REGULATOR receiver
BCM0045_3537	COG4841	protein insertion into membrane
BCM0045_3538	COG0824	Thioesterase
BCM0045_3544	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0045_3546	COG1132	(ABC) transporter
BCM0045_3547	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCM0045_3553	COG2211	Major facilitator Superfamily
BCM0045_3555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCM0045_3558	COG0183	Belongs to the thiolase family
BCM0045_3559	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0045_3560	COG1268	BioY protein
BCM0045_3561	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0045_3574	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_3576	COG5002	protein histidine kinase activity
BCM0045_3577	COG5002	protein histidine kinase activity
BCM0045_3578	COG0400	carboxylic ester hydrolase activity
BCM0045_3579	COG0346	lactoylglutathione lyase activity
BCM0045_3580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0045_3581	COG0069	glutamate synthase activity
BCM0045_3582	COG1902	pentaerythritol trinitrate reductase activity
BCM0045_3583	COG1329	Transcriptional regulator
BCM0045_3584	COG0010	Belongs to the arginase family
BCM0045_3589	COG2226	methyltransferase
BCM0045_3601	COG4846	Membrane protein involved in cytochrome C biogenesis
BCM0045_3602	COG0785	Cytochrome C biogenesis protein
BCM0045_3604	COG1473	amidohydrolase
BCM0045_3606	COG1131	(ABC) transporter
BCM0045_3608	COG0583	DNA-binding transcription factor activity
BCM0045_3610	COG1346	cytolysis
BCM0045_3613	COG0730	response to heat
BCM0045_3618	COG1132	(ABC) transporter
BCM0045_3619	COG1132	(ABC) transporter
BCM0045_3625	COG3639	organic phosphonate transmembrane transporter activity
BCM0045_3626	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BCM0045_3627	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_3628	COG0737	Belongs to the 5'-nucleotidase family
BCM0045_3630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCM0045_3634	COG1695	Transcriptional regulator
BCM0045_3635	COG0174	glutamine synthetase
BCM0045_3636	COG0789	Transcriptional regulator
BCM0045_3637	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCM0045_3638	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCM0045_3639	COG2860	membrane
BCM0045_3641	COG0464	growth
BCM0045_3645	COG2801	Transposase and inactivated derivatives
BCM0045_3649	COG1388	LysM domain
BCM0045_3649	COG3584	3D domain protein
BCM0045_3650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCM0045_3650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCM0045_3650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0045_3651	COG1105	Belongs to the carbohydrate kinase PfkB family
BCM0045_3652	COG1349	DNA-binding transcription factor activity
BCM0045_3653	COG1979	alcohol dehydrogenase
BCM0045_3654	COG2322	membrane
BCM0045_3656	COG1113	amino acid transport
BCM0045_3658	COG1408	metallophosphoesterase
BCM0045_3659	COG2116	formate transmembrane transporter activity
BCM0045_3661	COG2217	Heavy metal translocating P-type atpase
BCM0045_3662	COG2608	mercury ion transmembrane transporter activity
BCM0045_3663	COG1937	Protein conserved in bacteria
BCM0045_3671	COG2819	hydrolase of the alpha beta superfamily
BCM0045_3672	COG1120	ATPase activity
BCM0045_3673	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_3674	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_3675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_3676	COG0708	Exodeoxyribonuclease III
BCM0045_3677	COG2169	Transcriptional regulator
BCM0045_3678	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCM0045_3679	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCM0045_3681	COG2364	Membrane
BCM0045_3684	COG2267	carboxylic ester hydrolase activity
BCM0045_3685	COG0346	lactoylglutathione lyase activity
BCM0045_3686	COG5001	Diguanylate cyclase
BCM0045_3686	COG3300	MHYT domain
BCM0045_3690	COG1380	Effector of murein hydrolase LrgA
BCM0045_3691	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0045_3695	COG1404	Belongs to the peptidase S8 family
BCM0045_3696	COG3773	Cell wall hydrolase
BCM0045_3697	COG0562	UDP-galactopyranose mutase
BCM0045_3698	COG1368	sulfuric ester hydrolase activity
BCM0045_3699	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0045_3703	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCM0045_3704	COG2814	Major facilitator Superfamily
BCM0045_3706	COG0640	Transcriptional regulator
BCM0045_3710	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCM0045_3712	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCM0045_3713	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCM0045_3713	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCM0045_3715	COG2359	stage V sporulation protein S
BCM0045_3716	COG1692	metallophosphoesterase
BCM0045_3723	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCM0045_3724	COG1426	Protein conserved in bacteria
BCM0045_3727	COG0300	oxidoreductase activity
BCM0045_3728	COG0612	Peptidase, M16
BCM0045_3729	COG0612	Peptidase, M16
BCM0045_3730	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCM0045_3731	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCM0045_3732	COG3845	ABC transporter
BCM0045_3733	COG1744	ABC transporter substrate-binding protein PnrA-like
BCM0045_3734	COG2188	Transcriptional regulator
BCM0045_3735	COG1674	ftsk spoiiie
BCM0045_3737	COG0740	serine-type endopeptidase activity
BCM0045_3738	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0045_3741	COG0527	aspartate kinase activity
BCM0045_3742	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCM0045_3743	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCM0045_3744	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCM0045_3745	COG1873	PFAM PRC-barrel domain
BCM0045_3746	COG0612	Peptidase, M16
BCM0045_3747	COG0726	polysaccharide deacetylase
BCM0045_3750	COG0196	riboflavin kinase activity
BCM0045_3753	COG1550	Protein conserved in bacteria
BCM0045_3755	COG1358	cellular component organization or biogenesis
BCM0045_3756	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCM0045_3757	COG0195	Participates in both transcription termination and antitermination
BCM0045_3764	COG0750	zinc metalloprotease
BCM0045_3766	COG4589	Belongs to the CDS family
BCM0045_3769	COG0528	UMP kinase activity
BCM0045_3775	COG4974	Belongs to the 'phage' integrase family
BCM0045_3777	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCM0045_3778	COG0758	DNA mediated transformation
BCM0045_3779	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCM0045_3787	COG1837	Belongs to the UPF0109 family
BCM0045_3789	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCM0045_3791	COG0552	protein localization to endoplasmic reticulum
BCM0045_3792	COG1196	nuclear chromosome segregation
BCM0045_3794	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0045_3795	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3796	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCM0045_3799	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCM0045_3800	COG1461	Dihydroxyacetone kinase
BCM0045_3801	COG1302	Protein conserved in bacteria
BCM0045_3803	COG1564	THIamine pyrophosphokinase
BCM0045_3804	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCM0045_3805	COG1162	GTPase activity
BCM0045_3806	COG0515	serine threonine protein kinase
BCM0045_3806	COG2815	serine threonine protein kinase
BCM0045_3807	COG0631	protein serine/threonine phosphatase activity
BCM0045_3809	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCM0045_3809	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCM0045_3811	COG0242	peptide deformylase activity
BCM0045_3812	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCM0045_3813	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCM0045_3817	COG1561	YicC-like family, N-terminal region
BCM0045_3818	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCM0045_3820	COG0006	proline dipeptidase activity
BCM0045_3824	COG3069	C4-dicarboxylate transmembrane transporter activity
BCM0045_3836	COG0564	pseudouridine synthase activity
BCM0045_3840	COG3599	regulation of cell shape
BCM0045_3841	COG2302	S4 RNA-binding domain
BCM0045_3842	COG0762	integral membrane protein
BCM0045_3844	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCM0045_3845	COG1496	oxidoreductase activity
BCM0045_3846	COG1873	PFAM PRC-barrel domain
BCM0045_3847	COG1191	sigma factor activity
BCM0045_3848	COG1191	sigma factor activity
BCM0045_3850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCM0045_3851	COG0849	cell division
BCM0045_3852	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCM0045_3855	COG0772	Belongs to the SEDS family
BCM0045_3858	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCM0045_3859	COG0768	penicillin binding
BCM0045_3860	COG0768	penicillin binding
BCM0045_3861	COG4839	cell division protein FtsL
BCM0045_3864	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCM0045_3867	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCM0045_3868	COG1399	metal-binding, possibly nucleic acid-binding protein
BCM0045_3870	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCM0045_3871	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCM0045_3872	COG3314	Sporulation integral membrane protein YlbJ
BCM0045_3874	COG0742	ribosomal rna small subunit methyltransferase
BCM0045_3877	COG3679	Belongs to the UPF0342 family
BCM0045_3878	COG0406	alpha-ribazole phosphatase activity
BCM0045_3881	COG2340	Cysteine-rich secretory protein family
BCM0045_3884	COG3336	cytochrome c oxidase
BCM0045_3891	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCM0045_3892	COG0772	Belongs to the SEDS family
BCM0045_3894	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCM0045_3895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCM0045_3897	COG4896	Protein conserved in bacteria
BCM0045_3900	COG1217	gtp-binding protein TYPA
BCM0045_3902	COG0483	inositol monophosphate 1-phosphatase activity
BCM0045_3906	COG1982	Orn Lys Arg decarboxylase major
BCM0045_3916	COG0022	dehydrogenase e1 component
BCM0045_3917	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0045_3919	COG0242	peptide deformylase activity
BCM0045_3920	COG0561	phosphatase activity
BCM0045_3922	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0045_3923	COG0569	domain protein
BCM0045_3927	COG0583	DNA-binding transcription factor activity
BCM0045_3928	COG0517	IMP dehydrogenase activity
BCM0045_3930	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BCM0045_3932	COG4703	Protein of unknown function (DUF1797)
BCM0045_3935	COG2200	EAL domain
BCM0045_3936	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3937	COG1408	metallophosphoesterase
BCM0045_3939	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCM0045_3946	COG2814	Major facilitator Superfamily
BCM0045_3950	COG3209	COG3209 Rhs family protein
BCM0045_3952	COG2205	protein histidine kinase activity
BCM0045_3954	COG0436	Aminotransferase
BCM0045_3955	COG1609	Transcriptional regulator
BCM0045_3956	COG3833	ABC-type maltose transport systems, permease component
BCM0045_3957	COG1175	transmembrane transport
BCM0045_3958	COG2182	Extracellular solute-binding protein
BCM0045_3960	COG0366	Alpha amylase catalytic
BCM0045_3961	COG3842	ATPase activity
BCM0045_3969	COG0183	Belongs to the thiolase family
BCM0045_3976	COG1695	Transcriptional regulator
BCM0045_3977	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_3981	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCM0045_3982	COG0436	Aminotransferase
BCM0045_3989	COG2084	Dehydrogenase
BCM0045_3990	COG2199	diguanylate cyclase activity
BCM0045_3991	COG0778	Nitroreductase
BCM0045_3996	COG1263	PTS System
BCM0045_3996	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_3996	COG2190	(PTS) system
BCM0045_3997	COG3711	transcriptional antiterminator
BCM0045_3999	COG2188	Transcriptional regulator
BCM0045_4001	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCM0045_4005	COG1547	Domain of unknown function (DUF309)
BCM0045_4006	COG0456	acetyltransferase
BCM0045_4007	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCM0045_4008	COG4086	secreted protein
BCM0045_4009	COG0561	phosphatase activity
BCM0045_4010	COG0697	spore germination
BCM0045_4013	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0045_4017	COG0733	neurotransmitter:sodium symporter activity
BCM0045_4021	COG1686	Belongs to the peptidase S11 family
BCM0045_4022	COG1725	Transcriptional regulator
BCM0045_4023	COG1131	(ABC) transporter
BCM0045_4027	COG1846	Transcriptional regulator
BCM0045_4030	COG0598	Magnesium transport protein CorA
BCM0045_4035	COG4974	Belongs to the 'phage' integrase family
BCM0045_4037	COG0735	belongs to the Fur family
BCM0045_4038	COG1300	Membrane
BCM0045_4042	COG0667	Aldo Keto reductase
BCM0045_4043	COG0656	L-ascorbic acid biosynthetic process
BCM0045_4044	COG0456	acetyltransferase
BCM0045_4044	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0045_4046	COG1525	nuclease
BCM0045_4046	COG0737	Belongs to the 5'-nucleotidase family
BCM0045_4046	COG4085	toxin activity
BCM0045_4048	COG0596	Alpha beta hydrolase
BCM0045_4049	COG2056	Na+-H+ antiporter family
BCM0045_4050	COG1609	Transcriptional regulator
BCM0045_4051	COG0454	-acetyltransferase
BCM0045_4052	COG1073	alpha beta
BCM0045_4055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCM0045_4055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCM0045_4056	COG0307	riboflavin synthase, alpha
BCM0045_4061	COG4106	trans-aconitate 2-methyltransferase activity
BCM0045_4062	COG1073	alpha beta
BCM0045_4062	COG2226	methyltransferase
BCM0045_4065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0045_4067	COG1757	Na H antiporter
BCM0045_4068	COG0737	Belongs to the 5'-nucleotidase family
BCM0045_4070	COG1522	sequence-specific DNA binding
BCM0045_4074	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCM0045_4079	COG0300	oxidoreductase activity
BCM0045_4080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_4081	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0045_4082	COG1760	l-serine dehydratase
BCM0045_4083	COG1760	l-serine dehydratase
BCM0045_4087	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0045_4089	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCM0045_4090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_4092	COG1376	ErfK ybiS ycfS ynhG family protein
BCM0045_4093	COG4129	membrane
BCM0045_4094	COG1126	abc transporter atp-binding protein
BCM0045_4095	COG0765	amino acid transport
BCM0045_4096	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0045_4098	COG2816	NAD+ diphosphatase activity
BCM0045_4099	COG0772	Belongs to the SEDS family
BCM0045_4100	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0045_4101	COG0022	dehydrogenase e1 component
BCM0045_4102	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0045_4103	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCM0045_4106	COG0280	phosphate acetyltransferase
BCM0045_4107	COG3829	transcription factor binding
BCM0045_4107	COG3290	protein histidine kinase activity
BCM0045_4109	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0045_4110	COG3093	addiction module antidote protein HigA
BCM0045_4112	COG0745	RESPONSE REGULATOR receiver
BCM0045_4113	COG0750	zinc metalloprotease
BCM0045_4114	COG0497	DNA recombination
BCM0045_4116	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCM0045_4118	COG0142	geranyltranstransferase activity
BCM0045_4123	COG1302	Protein conserved in bacteria
BCM0045_4124	COG0439	Biotin carboxylase
BCM0045_4125	COG0511	ligase activity, forming carbon-carbon bonds
BCM0045_4133	COG3854	ATPases associated with a variety of cellular activities
BCM0045_4138	COG0006	proline dipeptidase activity
BCM0045_4141	COG3872	metal-dependent enzyme
BCM0045_4143	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCM0045_4150	COG0095	Lipoate-protein ligase
BCM0045_4151	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0045_4152	COG1609	Transcriptional regulator
BCM0045_4154	COG2076	Multidrug Resistance protein
BCM0045_4155	COG2076	Multidrug Resistance protein
BCM0045_4163	COG1131	(ABC) transporter
BCM0045_4164	COG1725	Transcriptional regulator
BCM0045_4170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0045_4181	COG4970	Tfp pilus assembly protein FimT
BCM0045_4183	COG1459	type II secretion system
BCM0045_4184	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCM0045_4194	COG1410	methionine synthase
BCM0045_4194	COG0646	methionine synthase
BCM0045_4195	COG0646	methionine synthase
BCM0045_4195	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCM0045_4196	COG0626	cystathionine gamma-synthase activity
BCM0045_4197	COG0626	cystathionine gamma-synthase activity
BCM0045_4201	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_4203	COG1940	carbohydrate kinase activity
BCM0045_4204	COG4483	Protein conserved in bacteria
BCM0045_4205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCM0045_4206	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCM0045_4207	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCM0045_4208	COG0704	Plays a role in the regulation of phosphate uptake
BCM0045_4210	COG0581	inorganic phosphate transmembrane transporter activity
BCM0045_4211	COG0573	inorganic phosphate transmembrane transporter activity
BCM0045_4212	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCM0045_4214	COG0768	penicillin binding
BCM0045_4215	COG0477	Major facilitator Superfamily
BCM0045_4216	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0045_4220	COG0735	belongs to the Fur family
BCM0045_4221	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCM0045_4222	COG1121	(ABC) transporter
BCM0045_4223	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_4229	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCM0045_4230	COG2384	SAM-dependent methyltransferase
BCM0045_4231	COG2010	Cytochrome c
BCM0045_4232	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCM0045_4233	COG0358	DNA primase activity
BCM0045_4235	COG0517	IMP dehydrogenase activity
BCM0045_4238	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCM0045_4239	COG0295	cytidine deaminase activity
BCM0045_4240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCM0045_4242	COG1480	7TM receptor with intracellular HD hydrolase
BCM0045_4243	COG1702	phosphate starvation-inducible protein PhoH
BCM0045_4246	COG1610	YqeY-like protein
BCM0045_4247	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCM0045_4248	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCM0045_4249	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCM0045_4255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCM0045_4256	COG1733	regulation of RNA biosynthetic process
BCM0045_4261	COG1466	dna polymerase III delta subunit
BCM0045_4263	COG0658	competence protein
BCM0045_4263	COG2333	competence protein COMEC
BCM0045_4264	COG2131	deaminase
BCM0045_4265	COG1555	photosystem II stabilization
BCM0045_4265	COG1596	polysaccharide export
BCM0045_4266	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0045_4267	COG2226	methyltransferase
BCM0045_4268	COG0799	negative regulation of ribosome biogenesis
BCM0045_4269	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCM0045_4271	COG1534	Rna-binding protein
BCM0045_4273	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCM0045_4274	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCM0045_4279	COG1595	DNA-templated transcription, initiation
BCM0045_4281	COG0778	Nitroreductase
BCM0045_4282	COG2357	RelA SpoT domain protein
BCM0045_4284	COG1785	Belongs to the alkaline phosphatase family
BCM0045_4286	COG2267	carboxylic ester hydrolase activity
BCM0045_4293	COG1404	Belongs to the peptidase S8 family
BCM0045_4294	COG3186	Phenylalanine-4-hydroxylase
BCM0045_4296	COG2514	catechol 2,3-dioxygenase activity
BCM0045_4297	COG2259	Doxx family
BCM0045_4305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCM0045_4307	COG1012	belongs to the aldehyde dehydrogenase family
BCM0045_4307	COG1454	alcohol dehydrogenase
BCM0045_4308	COG0626	cystathionine gamma-synthase activity
BCM0045_4309	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0045_4314	COG0768	penicillin binding
BCM0045_4317	COG0826	peptidase U32
BCM0045_4318	COG0826	peptidase U32
BCM0045_4319	COG4122	O-methyltransferase activity
BCM0045_4320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCM0045_4326	COG0628	permease
BCM0045_4330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCM0045_4333	COG1104	cysteine desulfurase activity
BCM0045_4334	COG1959	2 iron, 2 sulfur cluster binding
BCM0045_4335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCM0045_4338	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCM0045_4346	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCM0045_4348	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCM0045_4348	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCM0045_4349	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCM0045_4350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCM0045_4350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCM0045_4352	COG2244	polysaccharide biosynthetic process
BCM0045_4353	COG2323	membrane
BCM0045_4355	COG1862	Preprotein translocase
BCM0045_4361	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCM0045_4363	COG0697	spore germination
BCM0045_4364	COG0640	Transcriptional regulator
BCM0045_4369	COG0157	Belongs to the NadC ModD family
BCM0045_4370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCM0045_4371	COG1104	cysteine desulfurase activity
BCM0045_4372	COG1827	regulation of RNA biosynthetic process
BCM0045_4373	COG2258	MOSC domain
BCM0045_4374	COG0077	Prephenate dehydratase
BCM0045_4375	COG0577	efflux transmembrane transporter activity
BCM0045_4376	COG0577	efflux transmembrane transporter activity
BCM0045_4377	COG1136	(ABC) transporter
BCM0045_4378	COG5002	protein histidine kinase activity
BCM0045_4379	COG0745	RESPONSE REGULATOR receiver
BCM0045_4381	COG3290	protein histidine kinase activity
BCM0045_4383	COG2868	ribosomal protein
BCM0045_4384	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCM0045_4385	COG1530	ribonuclease E activity
BCM0045_4386	COG1994	Peptidase M50
BCM0045_4387	COG0739	heme binding
BCM0045_4388	COG2894	cell division
BCM0045_4392	COG1077	Cell shape determining protein MreB Mrl
BCM0045_4393	COG2003	Belongs to the UPF0758 family
BCM0045_4400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCM0045_4400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCM0045_4428	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCM0045_4439	COG0285	dihydrofolate synthase activity
BCM0045_4442	COG1388	LysM domain
BCM0045_4444	COG0113	porphobilinogen synthase activity
BCM0045_4445	COG1587	Uroporphyrinogen-III synthase
BCM0045_4447	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCM0045_4449	COG1846	Transcriptional regulator
BCM0045_4450	COG1764	response to oxidative stress
BCM0045_4453	COG0470	DNA polymerase III
BCM0045_4453	COG1067	ATP-dependent peptidase activity
BCM0045_4462	COG0622	Phosphoesterase
BCM0045_4465	COG5401	PFAM Sporulation and spore germination
BCM0045_4468	COG2197	response regulator
BCM0045_4469	COG2233	PERMEase
BCM0045_4470	COG0402	S-adenosylhomocysteine deaminase activity
BCM0045_4471	COG1983	PspC domain protein
BCM0045_4472	COG1396	sequence-specific DNA binding
BCM0045_4473	COG0697	spore germination
BCM0045_4475	COG1959	2 iron, 2 sulfur cluster binding
BCM0045_4476	COG1668	transmembrane transport
BCM0045_4477	COG4152	abc transporter atp-binding protein
BCM0045_4478	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCM0045_4479	COG1360	Flagellar Motor Protein
BCM0045_4480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCM0045_4481	COG1876	peptidase activity
BCM0045_4482	COG0824	Thioesterase
BCM0045_4483	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCM0045_4484	COG1053	succinate dehydrogenase
BCM0045_4485	COG2009	succinate dehydrogenase
BCM0045_4486	COG1719	4-vinyl reductase, 4VR
BCM0045_4488	COG3118	belongs to the thioredoxin family
BCM0045_4489	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCM0045_4490	COG2086	electron transfer activity
BCM0045_4491	COG1024	Enoyl-CoA hydratase
BCM0045_4492	COG1309	transcriptional regulator
BCM0045_4493	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0045_4495	COG2318	DinB family
BCM0045_4500	COG1131	(ABC) transporter
BCM0045_4501	COG2205	protein histidine kinase activity
BCM0045_4502	COG0745	RESPONSE REGULATOR receiver
BCM0045_4504	COG4895	conserved protein (DUF2196)
BCM0045_4505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCM0045_4508	COG4509	Sortase family
BCM0045_4509	COG1120	ATPase activity
BCM0045_4512	COG5386	Cell surface protein
BCM0045_4513	COG5386	Cell surface protein
BCM0045_4515	COG1114	Component of the transport system for branched-chain amino acids
BCM0045_4516	COG1187	pseudouridine synthase activity
BCM0045_4518	COG1796	DNA polymerase
BCM0045_4518	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCM0045_4519	COG1286	toxin biosynthetic process
BCM0045_4527	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCM0045_4529	COG1418	mRNA catabolic process
BCM0045_4531	COG2814	Major facilitator Superfamily
BCM0045_4532	COG1566	PFAM secretion protein HlyD family protein
BCM0045_4533	COG1309	transcriptional regulator
BCM0045_4534	COG1363	Peptidase, m42
BCM0045_4539	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCM0045_4541	COG1484	DNA-dependent DNA replication
BCM0045_4542	COG3611	Membrane attachment protein
BCM0045_4544	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCM0045_4545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCM0045_4546	COG0237	dephospho-CoA kinase activity
BCM0045_4547	COG1971	Probably functions as a manganese efflux pump
BCM0045_4549	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0045_4549	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0045_4550	COG5002	protein histidine kinase activity
BCM0045_4551	COG0745	RESPONSE REGULATOR receiver
BCM0045_4556	COG0538	isocitrate dehydrogenase activity
BCM0045_4557	COG0372	Belongs to the citrate synthase family
BCM0045_4559	COG0628	permease
BCM0045_4560	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCM0045_4565	COG1725	Transcriptional regulator
BCM0045_4566	COG0281	malic enzyme
BCM0045_4567	COG0587	DNA-directed DNA polymerase activity
BCM0045_4570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCM0045_4573	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0045_4575	COG4109	DRTGG domain
BCM0045_4578	COG0006	proline dipeptidase activity
BCM0045_4584	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_4585	COG0662	Cupin 2, conserved barrel domain protein
BCM0045_4588	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0045_4589	COG0589	response to stress
BCM0045_4597	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_4600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCM0045_4601	COG0827	DNA restriction-modification system
BCM0045_4602	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCM0045_4604	COG3874	Sporulation protein YtfJ
BCM0045_4607	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BCM0045_4609	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0045_4613	COG1104	cysteine desulfurase activity
BCM0045_4615	COG0583	DNA-binding transcription factor activity
BCM0045_4616	COG0697	spore germination
BCM0045_4617	COG1309	transcriptional regulator
BCM0045_4618	COG1956	GAF domain-containing protein
BCM0045_4619	COG0626	cystathionine gamma-synthase activity
BCM0045_4628	COG1595	DNA-templated transcription, initiation
BCM0045_4631	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0045_4632	COG0454	-acetyltransferase
BCM0045_4633	COG0517	IMP dehydrogenase activity
BCM0045_4634	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCM0045_4635	COG2267	carboxylic ester hydrolase activity
BCM0045_4637	COG0745	RESPONSE REGULATOR receiver
BCM0045_4639	COG0666	response to abiotic stimulus
BCM0045_4640	COG0745	RESPONSE REGULATOR receiver
BCM0045_4640	COG2972	Histidine kinase
BCM0045_4651	COG1609	Transcriptional regulator
BCM0045_4652	COG4851	CamS sex pheromone cAM373 precursor
BCM0045_4653	COG3118	belongs to the thioredoxin family
BCM0045_4655	COG2309	aminopeptidase activity
BCM0045_4657	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_4658	COG0697	spore germination
BCM0045_4659	COG0789	Transcriptional regulator
BCM0045_4660	COG1695	Transcriptional regulator
BCM0045_4664	COG1674	ftsk spoiiie
BCM0045_4664	COG1674	ftsk spoiiie
BCM0045_4666	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0045_4668	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0045_4669	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BCM0045_4670	COG1363	Peptidase, m42
BCM0045_4672	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_4675	COG0510	thiamine kinase activity
BCM0045_4676	COG1523	belongs to the glycosyl hydrolase 13 family
BCM0045_4678	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0045_4679	COG1349	DNA-binding transcription factor activity
BCM0045_4680	COG1187	pseudouridine synthase activity
BCM0045_4681	COG2244	polysaccharide biosynthetic process
BCM0045_4682	COG2081	HI0933 family
BCM0045_4683	COG3328	transposase activity
BCM0045_4685	COG2814	Major facilitator Superfamily
BCM0045_4687	COG3832	glyoxalase III activity
BCM0045_4691	COG1329	Transcriptional regulator
BCM0045_4696	COG0314	molybdopterin synthase activity
BCM0045_4699	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCM0045_4700	COG0303	'Molybdopterin
BCM0045_4702	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0045_4703	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCM0045_4707	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0045_4709	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCM0045_4718	COG2814	Major facilitator Superfamily
BCM0045_4719	COG3328	transposase activity
BCM0045_4720	COG3328	transposase activity
BCM0045_4721	COG0475	glutathione-regulated potassium exporter activity
BCM0045_4722	COG0490	domain, Protein
BCM0045_4723	COG0582	viral genome integration into host DNA
BCM0045_4725	COG1136	(ABC) transporter
BCM0045_4729	COG1242	4 iron, 4 sulfur cluster binding
BCM0045_4730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCM0045_4733	COG1794	racemase activity, acting on amino acids and derivatives
BCM0045_4738	COG2267	carboxylic ester hydrolase activity
BCM0045_4739	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCM0045_4740	COG0671	phosphoesterase, PA-phosphatase related
BCM0045_4741	COG0438	transferase activity, transferring glycosyl groups
BCM0045_4743	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCM0045_4753	COG3328	transposase activity
BCM0045_4754	COG3328	transposase activity
BCM0045_4759	COG5002	protein histidine kinase activity
BCM0045_4760	COG4191	Histidine kinase
BCM0045_4761	COG2267	carboxylic ester hydrolase activity
BCM0045_4762	COG1368	sulfuric ester hydrolase activity
BCM0045_4765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0045_4766	COG1116	anion transmembrane transporter activity
BCM0045_4767	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0045_4772	COG0494	nUDIX hydrolase
BCM0045_4778	COG0288	reversible hydration of carbon dioxide
BCM0045_4779	COG1271	oxidase subunit
BCM0045_4780	COG1294	oxidase, subunit
BCM0045_4784	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_4789	COG1842	Phage shock protein A
BCM0045_4795	COG5002	protein histidine kinase activity
BCM0045_4797	COG0745	RESPONSE REGULATOR receiver
BCM0045_4803	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCM0045_4805	COG1597	lipid kinase activity
BCM0045_4809	COG0586	Pfam SNARE associated Golgi protein
BCM0045_4811	COG4977	sequence-specific DNA binding
BCM0045_4813	COG0577	efflux transmembrane transporter activity
BCM0045_4814	COG1136	(ABC) transporter
BCM0045_4815	COG3708	Transcriptional regulator
BCM0045_4815	COG2207	Transcriptional regulator
BCM0045_4818	COG0745	RESPONSE REGULATOR receiver
BCM0045_4819	COG2205	protein histidine kinase activity
BCM0045_4820	COG0577	efflux transmembrane transporter activity
BCM0045_4821	COG0577	efflux transmembrane transporter activity
BCM0045_4822	COG0577	efflux transmembrane transporter activity
BCM0045_4823	COG1136	(ABC) transporter
BCM0045_4824	COG0577	efflux transmembrane transporter activity
BCM0045_4829	COG2188	Transcriptional regulator
BCM0045_4833	COG3964	amidohydrolase
BCM0045_4835	COG2801	Transposase and inactivated derivatives
BCM0045_4839	COG4948	Mandelate Racemase Muconate Lactonizing
BCM0045_4841	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCM0045_4842	COG0596	Alpha beta hydrolase
BCM0045_4844	COG1169	isochorismate synthase
BCM0045_4845	COG1575	Belongs to the MenA family. Type 1 subfamily
BCM0045_4846	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCM0045_4871	COG0058	SHG alpha-glucan phosphorylase activity
BCM0045_4873	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCM0045_4877	COG1404	Belongs to the peptidase S8 family
BCM0045_4880	COG1595	DNA-templated transcription, initiation
BCM0045_4881	COG1285	pathogenesis
BCM0045_4882	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCM0045_4885	COG2155	Conserved Protein
BCM0045_4886	COG1098	S1 RNA binding domain
BCM0045_4887	COG0436	Aminotransferase
BCM0045_4888	COG1522	sequence-specific DNA binding
BCM0045_4889	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCM0045_4890	COG2267	carboxylic ester hydrolase activity
BCM0045_4892	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCM0045_4896	COG5018	Exonuclease
BCM0045_4897	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0045_4902	COG2050	protein possibly involved in aromatic compounds catabolism
BCM0045_4904	COG1268	BioY protein
BCM0045_4905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCM0045_4906	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCM0045_4909	COG3584	3D domain protein
BCM0045_4912	COG1252	NADH dehydrogenase
BCM0045_4914	COG3708	Transcriptional regulator
BCM0045_4917	COG1683	Conserved Protein
BCM0045_4919	COG0316	Belongs to the HesB IscA family
BCM0045_4925	COG1252	NADH dehydrogenase
BCM0045_4926	COG2274	protein secretion by the type I secretion system
BCM0045_4927	COG0390	transport system, permease component
BCM0045_4928	COG3328	transposase activity
BCM0045_4929	COG3328	transposase activity
BCM0045_4930	COG2824	Alkylphosphonate utilization operon protein PhnA
BCM0045_4934	COG4837	Protein of unknown function (DUF1462)
BCM0045_4935	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCM0045_4937	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0045_4938	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCM0045_4940	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0045_4941	COG0647	UMP catabolic process
BCM0045_4943	COG2445	Protein of unknown function DUF86
BCM0045_4944	COG1494	fructose-1,6-bisphosphatase
BCM0045_4947	COG4470	Protein conserved in bacteria
BCM0045_4949	COG0789	Transcriptional regulator
BCM0045_4950	COG4377	Putative membrane peptidase family (DUF2324)
BCM0045_4955	COG0739	heme binding
BCM0045_4957	COG3377	Domain of unknown function (DUF1805)
BCM0045_4958	COG0737	Belongs to the 5'-nucleotidase family
BCM0045_4959	COG0719	Fe-S assembly protein
BCM0045_4960	COG0822	iron-sulfur transferase activity
BCM0045_4961	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCM0045_4962	COG0719	Fe-S assembly protein
BCM0045_4963	COG0396	ATPase activity
BCM0045_4964	COG1464	Belongs to the NlpA lipoprotein family
BCM0045_4965	COG1464	Belongs to the NlpA lipoprotein family
BCM0045_4966	COG2011	ABC-type metal ion transport system permease component
BCM0045_4969	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0045_4970	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCM0045_4972	COG1393	Belongs to the ArsC family
BCM0045_4986	COG1396	sequence-specific DNA binding
BCM0045_4988	COG1309	transcriptional regulator
BCM0045_4989	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0045_4990	COG1960	acyl-CoA dehydrogenase activity
BCM0045_4991	COG0183	Belongs to the thiolase family
BCM0045_4992	COG1024	Enoyl-CoA hydratase
BCM0045_4992	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCM0045_4994	COG1686	Belongs to the peptidase S11 family
BCM0045_4997	COG0011	TIGRFAM Protein of
BCM0045_4998	COG0840	transmembrane signaling receptor activity
BCM0045_5001	COG2814	Major facilitator Superfamily
BCM0045_5002	COG0531	amino acid
BCM0045_5007	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0045_5010	COG3328	transposase activity
BCM0045_5011	COG3328	transposase activity
BCM0045_5017	COG0586	Pfam SNARE associated Golgi protein
BCM0045_5019	COG1376	ErfK ybiS ycfS ynhG family protein
BCM0045_5020	COG0745	RESPONSE REGULATOR receiver
BCM0045_5021	COG5002	protein histidine kinase activity
BCM0045_5026	COG0840	transmembrane signaling receptor activity
BCM0045_5027	COG2151	metal-sulfur cluster biosynthetic enzyme
BCM0045_5028	COG3227	Zinc metalloprotease (Elastase)
BCM0045_5029	COG1741	Belongs to the pirin family
BCM0045_5032	COG0475	glutathione-regulated potassium exporter activity
BCM0045_5033	COG0490	domain, Protein
BCM0045_5035	COG1115	amino acid carrier protein
BCM0045_5036	COG0783	Belongs to the Dps family
BCM0045_5039	COG1611	Belongs to the LOG family
BCM0045_5042	COG2311	Membrane
BCM0045_5043	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_5044	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_5045	COG1115	amino acid carrier protein
BCM0045_5046	COG1115	amino acid carrier protein
BCM0045_5047	COG2910	NAD(P)H-binding
BCM0045_5052	COG0656	L-ascorbic acid biosynthetic process
BCM0045_5053	COG2814	Major facilitator Superfamily
BCM0045_5054	COG1733	regulation of RNA biosynthetic process
BCM0045_5056	COG1252	NADH dehydrogenase
BCM0045_5057	COG3328	transposase activity
BCM0045_5058	COG3328	transposase activity
BCM0045_5059	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCM0045_5062	COG0840	transmembrane signaling receptor activity
BCM0045_5062	COG3290	protein histidine kinase activity
BCM0045_5069	COG0488	(ABC) transporter
BCM0045_5070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0045_5072	COG2814	Major facilitator Superfamily
BCM0045_5082	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0045_5083	COG0697	spore germination
BCM0045_5086	COG0557	exoribonuclease II activity
BCM0045_5087	COG1647	Serine aminopeptidase, S33
BCM0045_5088	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCM0045_5089	COG1346	cytolysis
BCM0045_5096	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCM0045_5099	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCM0045_5103	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0045_5106	COG2323	membrane
BCM0045_5108	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0045_5110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCM0045_5112	COG1051	belongs to the nudix hydrolase family
BCM0045_5114	COG0492	ferredoxin-NADP+ reductase activity
BCM0045_5115	COG0457	Tetratricopeptide repeat
BCM0045_5116	COG0110	maltose O-acetyltransferase activity
BCM0045_5120	COG1950	PFAM Membrane protein of
BCM0045_5122	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCM0045_5123	COG0556	nucleotide-excision repair
BCM0045_5126	COG0789	Transcriptional regulator
BCM0045_5131	COG2855	membrane
BCM0045_5132	COG0583	DNA-binding transcription factor activity
BCM0045_5134	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCM0045_5135	COG0488	(ABC) transporter
BCM0045_5137	COG1132	(ABC) transporter
BCM0045_5138	COG3328	transposase activity
BCM0045_5139	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0045_5140	COG0793	Belongs to the peptidase S41A family
BCM0045_5140	COG3409	Peptidoglycan-binding domain 1 protein
BCM0045_5141	COG2177	Part of the ABC transporter FtsEX involved in
BCM0045_5142	COG2884	Cell division ATP-binding protein ftsE
BCM0045_5144	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCM0045_5147	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCM0045_5148	COG1278	Cold shock
BCM0045_5149	COG1040	competence protein
BCM0045_5150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCM0045_5151	COG0791	NLP P60 protein
BCM0045_5151	COG1388	LysM domain
BCM0045_5152	COG1733	regulation of RNA biosynthetic process
BCM0045_5153	COG1307	EDD domain protein, DegV family
BCM0045_5154	COG1739	Uncharacterized protein family UPF0029
BCM0045_5155	COG1316	TRANSCRIPTIONal
BCM0045_5156	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCM0045_5157	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCM0045_5158	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCM0045_5160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCM0045_5160	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCM0045_5164	COG1486	melibiose metabolic process
BCM0045_5165	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0045_5166	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0045_5168	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCM0045_5172	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0045_5174	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0045_5175	COG1301	dicarboxylic acid transport
BCM0045_5177	COG0346	lactoylglutathione lyase activity
BCM0045_5181	COG1511	domain protein
BCM0045_5182	COG0583	DNA-binding transcription factor activity
BCM0045_5183	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCM0045_5185	COG1271	oxidase subunit
BCM0045_5186	COG1294	oxidase, subunit
BCM0045_5187	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0045_5189	COG1620	l-lactate permease
BCM0045_5193	COG1620	l-lactate permease
BCM0045_5195	COG2389	metal-binding protein
BCM0045_5198	COG1368	sulfuric ester hydrolase activity
BCM0045_5200	COG0791	NLP P60 protein
BCM0045_5200	COG1388	LysM domain
BCM0045_5201	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0045_5203	COG1215	transferase activity, transferring glycosyl groups
BCM0045_5205	COG2801	Transposase and inactivated derivatives
BCM0045_5207	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0045_5208	COG3584	3D domain protein
BCM0045_5208	COG1388	LysM domain
BCM0045_5210	COG4715	Zinc finger, swim domain protein
BCM0045_5211	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0045_5220	COG0577	efflux transmembrane transporter activity
BCM0045_5221	COG1136	(ABC) transporter
BCM0045_5228	COG3850	Histidine kinase
BCM0045_5228	COG5002	protein histidine kinase activity
BCM0045_5229	COG0745	RESPONSE REGULATOR receiver
BCM0045_5230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCM0045_5234	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCM0045_5236	COG0438	transferase activity, transferring glycosyl groups
BCM0045_5237	COG1045	serine acetyltransferase
BCM0045_5239	COG0438	transferase activity, transferring glycosyl groups
BCM0045_5240	COG0438	transferase activity, transferring glycosyl groups
BCM0045_5241	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCM0045_5242	COG0151	Belongs to the GarS family
BCM0045_5244	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCM0045_5245	COG1086	Polysaccharide biosynthesis protein
BCM0045_5246	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCM0045_5247	COG4464	protein tyrosine phosphatase activity
BCM0045_5248	COG0489	protein tyrosine kinase activity
BCM0045_5249	COG3944	biosynthesis protein
BCM0045_5250	COG0489	protein tyrosine kinase activity
BCM0045_5253	COG1609	Transcriptional regulator
BCM0045_5255	COG0739	heme binding
BCM0045_5258	COG3279	Response regulator of the LytR AlgR family
BCM0045_5259	COG2385	sporulation resulting in formation of a cellular spore
BCM0045_5262	COG4836	Membrane
BCM0045_5263	COG1007	ATP synthesis coupled electron transport
BCM0045_5265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCM0045_5267	COG0839	Belongs to the complex I subunit 6 family
BCM0045_5271	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCM0045_5274	COG5001	Diguanylate cyclase
BCM0045_5274	COG3300	MHYT domain
BCM0045_5284	COG0356	it plays a direct role in the translocation of protons across the membrane
BCM0045_5290	COG0698	ribose 5-phosphate isomerase
BCM0045_5292	COG2190	(PTS) system
BCM0045_5293	COG2259	Doxx family
BCM0045_5294	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCM0045_5299	COG0009	L-threonylcarbamoyladenylate synthase
BCM0045_5302	COG2890	protein-(glutamine-N5) methyltransferase activity
BCM0045_5306	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCM0045_5307	COG1494	fructose-1,6-bisphosphatase
BCM0045_5311	COG4821	SIS domain
BCM0045_5315	COG1960	acyl-CoA dehydrogenase activity
BCM0045_5316	COG1960	acyl-CoA dehydrogenase activity
BCM0045_5317	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCM0045_5318	COG0183	Belongs to the thiolase family
BCM0045_5319	COG0247	lactate metabolic process
BCM0045_5319	COG2181	nitrate reductase activity
BCM0045_5320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0045_5322	COG5001	Diguanylate cyclase
BCM0045_5322	COG3300	MHYT domain
BCM0045_5326	COG2197	response regulator
BCM0045_5327	COG4585	Histidine kinase
BCM0045_5328	COG0842	Transport permease protein
BCM0045_5329	COG1131	(ABC) transporter
BCM0045_5330	COG0024	Methionine aminopeptidase
BCM0045_5331	COG2234	aminopeptidase activity
BCM0045_5335	COG1595	DNA-templated transcription, initiation
BCM0045_5337	COG4506	Protein conserved in bacteria
BCM0045_5338	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0045_5341	COG0010	Belongs to the arginase family
BCM0045_5343	COG2814	Major facilitator Superfamily
BCM0045_5344	COG0789	Transcriptional regulator
BCM0045_5345	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0045_5346	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0045_5348	COG1994	Peptidase M50
BCM0045_5350	COG1078	dGTPase activity
BCM0045_5351	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0045_5352	COG1120	ATPase activity
BCM0045_5353	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_5354	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0045_5358	COG0095	Lipoate-protein ligase
BCM0045_5359	COG0280	phosphate acetyltransferase
BCM0045_5362	COG3773	Cell wall hydrolase
BCM0045_5364	COG2363	Small membrane protein
BCM0045_5366	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCM0045_5367	COG2233	PERMEase
BCM0045_5368	COG0561	phosphatase activity
BCM0045_5369	COG2814	Major facilitator Superfamily
BCM0045_5371	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0045_5372	COG1131	(ABC) transporter
BCM0045_5373	COG2755	lipolytic protein G-D-S-L family
BCM0045_5374	COG1609	Transcriptional regulator
BCM0045_5376	COG0460	homoserine dehydrogenase
BCM0045_5378	COG2873	o-acetylhomoserine
BCM0045_5379	COG1011	Hydrolase
BCM0045_5380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCM0045_5382	COG2197	response regulator
BCM0045_5383	COG4585	Histidine kinase
BCM0045_5383	COG2203	Gaf domain
BCM0045_5384	COG0351	phosphomethylpyrimidine kinase
BCM0045_5385	COG3706	GGDEF domain
BCM0045_5386	COG2879	small protein
BCM0045_5387	COG1966	Carbon starvation protein
BCM0045_5388	COG3279	Response regulator of the LytR AlgR family
BCM0045_5389	COG0477	Major facilitator Superfamily
BCM0045_5394	COG0840	transmembrane signaling receptor activity
BCM0045_5396	COG1607	acyl-coa hydrolase
BCM0045_5397	COG1216	Glycosyl transferase, family 2
BCM0045_5399	COG0488	(ABC) transporter
BCM0045_5403	COG0463	Glycosyl transferase, family 2
BCM0045_5404	COG1309	transcriptional regulator
BCM0045_5405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCM0045_5406	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0045_5406	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0045_5407	COG0628	permease
BCM0045_5410	COG3279	Response regulator of the LytR AlgR family
BCM0045_5411	COG3275	phosphorelay sensor kinase activity
BCM0045_5412	COG2814	Major facilitator Superfamily
BCM0045_5413	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0045_5414	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BCM0045_5415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0045_5425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCM0045_5426	COG1272	protein, Hemolysin III
BCM0045_5432	COG1164	Oligoendopeptidase f
BCM0045_5434	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCM0045_5442	COG4974	Belongs to the 'phage' integrase family
BCM0045_5454	COG1196	nuclear chromosome segregation
BCM0045_5458	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0045_5459	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCM0045_5460	COG4853	Protein conserved in bacteria
BCM0045_5461	COG4863	YycH protein
BCM0045_5462	COG5002	protein histidine kinase activity
BCM0045_5463	COG0745	RESPONSE REGULATOR receiver
BCM0045_5465	COG0305	Participates in initiation and elongation during chromosome replication
BCM0045_5467	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCM0045_5468	COG4241	membrane
BCM0045_5470	COG0629	single-stranded DNA binding
BCM0045_5472	COG0012	GTP binding
BCM0045_5473	COG4481	Protein conserved in bacteria
BCM0045_5474	COG0668	transmembrane transport
BCM0045_5476	COG1475	DNA binding
BCM0045_5477	COG1192	Involved in chromosome partitioning
BCM0045_5482	COG1847	R3H domain protein
BCM0045_5483	COG0706	membrane insertase activity
BCM0045_5485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCM0045_p1014	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCM0045_p1018	COG4166	transmembrane transport
BCM0045_p1019	COG0747	negative chemotaxis
BCM0045_p1023	COG2002	toxin-antitoxin pair type II binding
BCM0045_p1032	COG0776	regulation of translation
BCM0045_p1038	COG2311	Membrane
BCM0045_p1045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCM0045_p1046	COG1621	beta-fructofuranosidase activity
BCM0045_p1047	COG1263	PTS System
BCM0045_p1047	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0045_p1048	COG1609	Transcriptional regulator
BCM0045_p1099	COG2801	Transposase and inactivated derivatives
BCM0045_p1150	COG1309	transcriptional regulator
BCM0045_p1160	COG0640	Transcriptional regulator
BCM0045_p1171	COG3103	Sh3 type 3 domain protein
BCM0045_p1171	COG1388	LysM domain
BCM0045_p1171	COG0791	NLP P60 protein
BCM0045_p1180	COG3397	chitin binding
BCM0045_p1191	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCM0045_p1194	COG2003	Belongs to the UPF0758 family
BCM0045_p1200	COG0582	viral genome integration into host DNA
BCM0045_p1201	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCM0045_p1208	COG1396	sequence-specific DNA binding
BCM0045_p1221	COG3344	reverse transcriptase
BCM0045_p1225	COG3344	reverse transcriptase
BCM0045_p1249	COG0457	Tetratricopeptide repeat
BCM0045_p1252	COG4974	Belongs to the 'phage' integrase family
BCM0045_p1258	COG5002	protein histidine kinase activity
BCM0045_p1260	COG0745	RESPONSE REGULATOR receiver
BCM0045_p1261	COG4990	cell redox homeostasis
BCM0045_p1262	COG1335	isochorismatase
BCM0045_p1272	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCM0045_p1272	COG2918	glutathione biosynthetic process
BCM0045_p1274	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BCM0045_p1276	COG1733	regulation of RNA biosynthetic process
BCM0045_p1280	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0045_p1283	COG2207	Transcriptional regulator
BCM0045_p1283	COG3708	Transcriptional regulator
BCM0045_t0098	COG0544	peptidyl-prolyl cis-trans isomerase activity