locus-tag	class	description
BCM0060_0002	COG0592	DNA-directed DNA polymerase activity
BCM0060_0003	COG2501	S4 domain
BCM0060_0005	COG0187	DNA topoisomerase II activity
BCM0060_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCM0060_0008	COG0516	GMP reductase activity
BCM0060_0008	COG0517	IMP dehydrogenase activity
BCM0060_0009	COG1686	Belongs to the peptidase S11 family
BCM0060_0014	COG1428	Deoxynucleoside kinase
BCM0060_0015	COG1428	Deoxynucleoside kinase
BCM0060_0016	COG1335	isochorismatase
BCM0060_0017	COG0590	tRNA wobble adenosine to inosine editing
BCM0060_0018	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCM0060_0024	COG1982	Orn Lys Arg decarboxylase major
BCM0060_0026	COG0470	DNA polymerase III
BCM0060_0027	COG1774	PSP1 C-terminal conserved region
BCM0060_0029	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCM0060_0031	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCM0060_0032	COG2002	toxin-antitoxin pair type II binding
BCM0060_0033	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0060_0033	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0060_0034	COG0084	hydrolase, TatD family'
BCM0060_0035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCM0060_0038	COG4466	Protein conserved in bacteria
BCM0060_0041	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCM0060_0042	COG0251	oxidation-reduction process
BCM0060_0048	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCM0060_0049	COG2002	toxin-antitoxin pair type II binding
BCM0060_0050	COG2244	polysaccharide biosynthetic process
BCM0060_0051	COG3956	TIGRFAM MazG family protein
BCM0060_0052	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCM0060_0056	COG1098	S1 RNA binding domain
BCM0060_0057	COG2208	phosphoserine phosphatase activity
BCM0060_0059	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCM0060_0060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCM0060_0063	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0060_0064	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCM0060_0065	COG0512	Glutamine amidotransferase of anthranilate synthase
BCM0060_0066	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0060_0067	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCM0060_0068	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCM0060_0069	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCM0060_0070	COG1396	sequence-specific DNA binding
BCM0060_0071	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCM0060_0074	COG3880	PFAM UvrB UvrC protein
BCM0060_0076	COG0542	response to heat
BCM0060_0077	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCM0060_0079	COG4956	integral membrane protein (PIN domain superfamily)
BCM0060_0083	COG1045	serine acetyltransferase
BCM0060_0086	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCM0060_0087	COG3688	RNA-binding protein containing a PIN domain
BCM0060_0089	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCM0060_0090	COG0250	Participates in transcription elongation, termination and antitermination
BCM0060_0091	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCM0060_0095	COG2813	Specifically methylates the guanine in position
BCM0060_0098	COG1358	cellular component organization or biogenesis
BCM0060_0112	COG0255	Belongs to the universal ribosomal protein uL29 family
BCM0060_0124	COG0201	protein transport
BCM0060_0126	COG0024	Methionine aminopeptidase
BCM0060_0134	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCM0060_0139	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0060_0140	COG0489	protein tyrosine kinase activity
BCM0060_0142	COG2194	sulfuric ester hydrolase activity
BCM0060_0143	COG0726	polysaccharide deacetylase
BCM0060_0148	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCM0060_0149	COG4856	YbbR-like protein
BCM0060_0157	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCM0060_0158	COG0823	Involved in the tonB-independent uptake of proteins
BCM0060_0158	COG1506	peptidase
BCM0060_0158	COG4946	Tricorn protease homolog
BCM0060_0164	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_0165	COG2011	ABC-type metal ion transport system permease component
BCM0060_0166	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCM0060_0167	COG1464	Belongs to the NlpA lipoprotein family
BCM0060_0168	COG0604	alcohol dehydrogenase
BCM0060_0170	COG0277	FAD linked oxidase domain protein
BCM0060_0171	COG2271	Major facilitator Superfamily
BCM0060_0173	COG2814	Major facilitator Superfamily
BCM0060_0176	COG0601	transmembrane transport
BCM0060_0177	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0060_0178	COG0444	Belongs to the ABC transporter superfamily
BCM0060_0179	COG4608	Belongs to the ABC transporter superfamily
BCM0060_0180	COG4166	transmembrane transport
BCM0060_0182	COG2207	Transcriptional regulator
BCM0060_0184	COG1309	transcriptional regulator
BCM0060_0186	COG4166	transmembrane transport
BCM0060_0187	COG4166	transmembrane transport
BCM0060_0188	COG0656	L-ascorbic acid biosynthetic process
BCM0060_0189	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0060_0192	COG4149	molybdate abc transporter
BCM0060_0193	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCM0060_0194	COG1910	domain protein
BCM0060_0196	COG0697	spore germination
BCM0060_0198	COG0204	Acyl-transferase
BCM0060_0199	COG1609	Transcriptional regulator
BCM0060_0201	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_0203	COG0084	hydrolase, TatD family'
BCM0060_0205	COG5298	Protein conserved in bacteria
BCM0060_0210	COG0488	(ABC) transporter
BCM0060_0212	COG0747	negative chemotaxis
BCM0060_0213	COG0601	transmembrane transport
BCM0060_0214	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0060_0215	COG0444	Belongs to the ABC transporter superfamily
BCM0060_0216	COG4608	Belongs to the ABC transporter superfamily
BCM0060_0217	COG0561	phosphatase activity
BCM0060_0220	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BCM0060_0221	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCM0060_0223	COG0531	amino acid
BCM0060_0224	COG2814	Major facilitator Superfamily
BCM0060_0226	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCM0060_0228	COG4294	response to UV
BCM0060_0229	COG0705	Rhomboid family
BCM0060_0229	COG0457	Tetratricopeptide repeat
BCM0060_0231	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCM0060_0232	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCM0060_0233	COG0864	Transcriptional regulator
BCM0060_0234	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCM0060_0235	COG2183	response to ionizing radiation
BCM0060_0237	COG0802	atpase or kinase
BCM0060_0238	COG1214	PFAM Peptidase M22, glycoprotease
BCM0060_0239	COG0456	acetyltransferase
BCM0060_0241	COG0488	(ABC) transporter
BCM0060_0244	COG1266	CAAX protease self-immunity
BCM0060_0247	COG5444	nuclease activity
BCM0060_0250	COG2252	PERMEase
BCM0060_0252	COG5002	protein histidine kinase activity
BCM0060_0254	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCM0060_0257	COG0697	spore germination
BCM0060_0259	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCM0060_0260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCM0060_0261	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCM0060_0263	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCM0060_0266	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCM0060_0268	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCM0060_0270	COG0151	Belongs to the GarS family
BCM0060_0275	COG0210	DNA helicase
BCM0060_0277	COG4851	CamS sex pheromone cAM373 precursor
BCM0060_0281	COG1335	isochorismatase
BCM0060_0283	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCM0060_0284	COG2011	ABC-type metal ion transport system permease component
BCM0060_0285	COG1464	Belongs to the NlpA lipoprotein family
BCM0060_0287	COG0003	Pfam Anion-transporting ATPase
BCM0060_0288	COG1846	Transcriptional regulator
BCM0060_0289	COG4682	membrane
BCM0060_0293	COG1597	lipid kinase activity
BCM0060_0294	COG0546	phosphoglycolate phosphatase activity
BCM0060_0295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCM0060_0297	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_0298	COG2076	Multidrug Resistance protein
BCM0060_0299	COG2309	aminopeptidase activity
BCM0060_0302	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_0303	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCM0060_0304	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCM0060_0305	COG5002	protein histidine kinase activity
BCM0060_0306	COG4807	Protein conserved in bacteria
BCM0060_0311	COG1757	Na H antiporter
BCM0060_0312	COG1473	amidohydrolase
BCM0060_0315	COG0450	alkyl hydroperoxide reductase
BCM0060_0320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_0321	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_0322	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_0326	COG0166	Belongs to the GPI family
BCM0060_0331	COG5002	protein histidine kinase activity
BCM0060_0335	COG3541	Predicted nucleotidyltransferase
BCM0060_0336	COG2814	Major facilitator Superfamily
BCM0060_0337	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0060_0337	COG0723	plastoquinol--plastocyanin reductase activity
BCM0060_0339	COG0765	amino acid transport
BCM0060_0340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0060_0342	COG0840	transmembrane signaling receptor activity
BCM0060_0343	COG0840	transmembrane signaling receptor activity
BCM0060_0344	COG0366	Alpha amylase catalytic
BCM0060_0345	COG1263	PTS System
BCM0060_0345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_0345	COG2190	(PTS) system
BCM0060_0351	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCM0060_0354	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0060_0356	COG1116	anion transmembrane transporter activity
BCM0060_0358	COG0488	(ABC) transporter
BCM0060_0368	COG2270	Major facilitator Superfamily
BCM0060_0374	COG2310	stress, protein
BCM0060_0375	COG2310	stress, protein
BCM0060_0376	COG2310	stress, protein
BCM0060_0377	COG0861	Integral membrane protein TerC family
BCM0060_0379	COG3853	Toxic anion resistance protein (TelA)
BCM0060_0382	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCM0060_0384	COG1295	ribonuclease BN
BCM0060_0386	COG2217	Heavy metal translocating P-type atpase
BCM0060_0387	COG0697	spore germination
BCM0060_0389	COG0681	Belongs to the peptidase S26 family
BCM0060_0391	COG0586	Pfam SNARE associated Golgi protein
BCM0060_0394	COG3871	stress protein (general stress protein 26)
BCM0060_0395	COG0387	Pfam Sodium calcium exchanger
BCM0060_0397	COG0535	radical SAM domain protein
BCM0060_0401	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCM0060_0404	COG3829	transcription factor binding
BCM0060_0406	COG0833	amino acid
BCM0060_0407	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0060_0413	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_0413	COG1263	PTS System
BCM0060_0414	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0060_0417	COG0463	Glycosyl transferase, family 2
BCM0060_0419	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCM0060_0419	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCM0060_0422	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCM0060_0427	COG1228	amidohydrolase
BCM0060_0428	COG1090	epimerase
BCM0060_0434	COG1988	membrane-bound metal-dependent
BCM0060_0435	COG1194	a g-specific adenine glycosylase
BCM0060_0440	COG1132	(ABC) transporter
BCM0060_0441	COG4129	membrane
BCM0060_0442	COG0069	glutamate synthase activity
BCM0060_0442	COG0070	glutamate synthase
BCM0060_0442	COG0067	glutamate synthase
BCM0060_0444	COG4555	ABC transporter
BCM0060_0448	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCM0060_0449	COG0735	belongs to the Fur family
BCM0060_0461	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCM0060_0462	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCM0060_0464	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCM0060_0466	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCM0060_0467	COG1716	ATPase activity
BCM0060_0467	COG5001	Diguanylate cyclase
BCM0060_0468	COG2766	serine protein kinase
BCM0060_0473	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0060_0475	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCM0060_0476	COG2268	Band 7 protein
BCM0060_0478	COG3290	protein histidine kinase activity
BCM0060_0479	COG4565	transcriptional regulatory protein
BCM0060_0480	COG2851	Citrate transporter
BCM0060_0484	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCM0060_0485	COG0745	RESPONSE REGULATOR receiver
BCM0060_0486	COG5002	protein histidine kinase activity
BCM0060_0488	COG4990	cell redox homeostasis
BCM0060_0490	COG3290	protein histidine kinase activity
BCM0060_0491	COG4565	transcriptional regulatory protein
BCM0060_0492	COG3493	citrate carrier protein
BCM0060_0493	COG0281	malic enzyme
BCM0060_0496	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_0498	COG5002	protein histidine kinase activity
BCM0060_0499	COG0745	RESPONSE REGULATOR receiver
BCM0060_0501	COG0456	acetyltransferase
BCM0060_0501	COG0454	-acetyltransferase
BCM0060_0502	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCM0060_0503	COG3383	formate dehydrogenase (NAD+) activity
BCM0060_0504	COG2427	Protein of unknown function (DUF1641)
BCM0060_0507	COG0531	amino acid
BCM0060_0508	COG0640	Transcriptional regulator
BCM0060_0509	COG2217	Heavy metal translocating P-type atpase
BCM0060_0510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCM0060_0513	COG3227	Zinc metalloprotease (Elastase)
BCM0060_0517	COG2720	vancomycin resistance protein
BCM0060_0518	COG1316	TRANSCRIPTIONal
BCM0060_0519	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_0520	COG0346	lactoylglutathione lyase activity
BCM0060_0521	COG1253	flavin adenine dinucleotide binding
BCM0060_0522	COG1027	Aspartate ammonia-lyase
BCM0060_0523	COG1620	l-lactate permease
BCM0060_0526	COG3104	oligopeptide transport
BCM0060_0527	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_0528	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_0529	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_0532	COG0156	8-amino-7-oxononanoate synthase activity
BCM0060_0533	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCM0060_0534	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCM0060_0536	COG4548	von Willebrand factor, type A
BCM0060_0537	COG0714	Associated with various cellular activities
BCM0060_0538	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0060_0541	COG0531	amino acid
BCM0060_0542	COG2188	Transcriptional regulator
BCM0060_0543	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_0543	COG1263	PTS System
BCM0060_0544	COG0366	Alpha amylase catalytic
BCM0060_0550	COG0697	spore germination
BCM0060_0551	COG4585	Histidine kinase
BCM0060_0552	COG2197	response regulator
BCM0060_0554	COG1404	Belongs to the peptidase S8 family
BCM0060_0558	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0060_0559	COG1115	amino acid carrier protein
BCM0060_0560	COG1126	abc transporter atp-binding protein
BCM0060_0561	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0060_0562	COG0765	amino acid transport
BCM0060_0563	COG0765	amino acid transport
BCM0060_0564	COG0833	amino acid
BCM0060_0567	COG1595	DNA-templated transcription, initiation
BCM0060_0569	COG2378	regulation of single-species biofilm formation
BCM0060_0570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCM0060_0571	COG5002	protein histidine kinase activity
BCM0060_0574	COG0659	secondary active sulfate transmembrane transporter activity
BCM0060_0577	COG0747	negative chemotaxis
BCM0060_0579	COG0601	transmembrane transport
BCM0060_0580	COG4608	Belongs to the ABC transporter superfamily
BCM0060_0582	COG2271	Major facilitator Superfamily
BCM0060_0583	COG1846	Transcriptional regulator
BCM0060_0584	COG0477	Major facilitator Superfamily
BCM0060_0585	COG1609	Transcriptional regulator
BCM0060_0586	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCM0060_0589	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCM0060_0590	COG1879	ABC-type sugar transport system periplasmic component
BCM0060_0594	COG1063	alcohol dehydrogenase
BCM0060_0597	COG3568	Endonuclease Exonuclease Phosphatase
BCM0060_0603	COG0840	transmembrane signaling receptor activity
BCM0060_0604	COG3584	3D domain protein
BCM0060_0604	COG1388	LysM domain
BCM0060_0605	COG1476	TRANSCRIPTIONal
BCM0060_0608	COG3104	oligopeptide transport
BCM0060_0609	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_0612	COG1113	amino acid transport
BCM0060_0613	COG2252	PERMEase
BCM0060_0616	COG2153	protein acetylation
BCM0060_0618	COG0569	domain protein
BCM0060_0618	COG0475	glutathione-regulated potassium exporter activity
BCM0060_0621	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCM0060_0622	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCM0060_0623	COG4990	cell redox homeostasis
BCM0060_0626	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0060_0627	COG0697	spore germination
BCM0060_0628	COG0531	amino acid
BCM0060_0630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0060_0631	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0060_0632	COG1918	ferrous iron import across plasma membrane
BCM0060_0632	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCM0060_0633	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCM0060_0634	COG0573	inorganic phosphate transmembrane transporter activity
BCM0060_0635	COG0581	inorganic phosphate transmembrane transporter activity
BCM0060_0637	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCM0060_0638	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BCM0060_0642	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCM0060_0643	COG1116	anion transmembrane transporter activity
BCM0060_0644	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0060_0645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0060_0646	COG0352	thiamine-phosphate diphosphorylase activity
BCM0060_0647	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0060_0648	COG2104	thiamine diphosphate biosynthetic process
BCM0060_0650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0060_0651	COG0351	phosphomethylpyrimidine kinase
BCM0060_0658	COG2205	protein histidine kinase activity
BCM0060_0659	COG2814	Major facilitator Superfamily
BCM0060_0660	COG1846	Transcriptional regulator
BCM0060_0665	COG1136	(ABC) transporter
BCM0060_0665	COG0577	efflux transmembrane transporter activity
BCM0060_0667	COG2252	PERMEase
BCM0060_0668	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_0671	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCM0060_0672	COG1621	beta-fructofuranosidase activity
BCM0060_0673	COG1263	PTS System
BCM0060_0673	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_0674	COG1609	Transcriptional regulator
BCM0060_0676	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0060_0684	COG0778	Nitroreductase
BCM0060_0685	COG2719	SpoVR family
BCM0060_0686	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCM0060_0687	COG1937	Protein conserved in bacteria
BCM0060_0688	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0060_0688	COG0425	Belongs to the sulfur carrier protein TusA family
BCM0060_0689	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_0689	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0060_0690	COG0425	Belongs to the sulfur carrier protein TusA family
BCM0060_0691	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0060_0693	COG2210	Belongs to the sulfur carrier protein TusA family
BCM0060_0694	COG0730	response to heat
BCM0060_0696	COG1316	TRANSCRIPTIONal
BCM0060_0697	COG0604	alcohol dehydrogenase
BCM0060_0698	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCM0060_0701	COG3711	transcriptional antiterminator
BCM0060_0701	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0060_0702	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0060_0703	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0060_0707	COG1388	LysM domain
BCM0060_0707	COG3584	3D domain protein
BCM0060_0708	COG0577	efflux transmembrane transporter activity
BCM0060_0709	COG1136	(ABC) transporter
BCM0060_0711	COG5522	Integral membrane protein (intg_mem_TP0381)
BCM0060_0714	COG0577	efflux transmembrane transporter activity
BCM0060_0715	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_0716	COG3546	catalase activity
BCM0060_0723	COG0586	Pfam SNARE associated Golgi protein
BCM0060_0730	COG0531	amino acid
BCM0060_0732	COG0475	glutathione-regulated potassium exporter activity
BCM0060_0734	COG1737	Transcriptional regulator
BCM0060_0736	COG1263	PTS System
BCM0060_0736	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_0739	COG2259	Doxx family
BCM0060_0743	COG1522	sequence-specific DNA binding
BCM0060_0746	COG2076	Multidrug Resistance protein
BCM0060_0747	COG1309	transcriptional regulator
BCM0060_0748	COG2814	Major facilitator Superfamily
BCM0060_0755	COG1136	(ABC) transporter
BCM0060_0756	COG0577	efflux transmembrane transporter activity
BCM0060_0757	COG1136	(ABC) transporter
BCM0060_0758	COG0577	efflux transmembrane transporter activity
BCM0060_0761	COG1733	regulation of RNA biosynthetic process
BCM0060_0765	COG4533	DNA binding
BCM0060_0766	COG2211	Major facilitator Superfamily
BCM0060_0768	COG0693	protein deglycase activity
BCM0060_0769	COG0753	catalase activity
BCM0060_0769	COG0693	protein deglycase activity
BCM0060_0771	COG0531	amino acid
BCM0060_0774	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_0775	COG1132	(ABC) transporter
BCM0060_0776	COG1132	(ABC) transporter
BCM0060_0777	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0060_0778	COG0765	amino acid transport
BCM0060_0779	COG1126	abc transporter atp-binding protein
BCM0060_0782	COG0189	ligase activity
BCM0060_0788	COG0028	Belongs to the TPP enzyme family
BCM0060_0789	COG3527	Alpha-acetolactate decarboxylase
BCM0060_0791	COG0561	phosphatase activity
BCM0060_0793	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0060_0793	COG3409	Peptidoglycan-binding domain 1 protein
BCM0060_0794	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCM0060_0797	COG0659	secondary active sulfate transmembrane transporter activity
BCM0060_0800	COG0653	protein targeting
BCM0060_0801	COG2244	polysaccharide biosynthetic process
BCM0060_0804	COG4196	transglutaminase domain protein
BCM0060_0805	COG4196	transglutaminase domain protein
BCM0060_0809	COG1024	Enoyl-CoA hydratase
BCM0060_0812	COG1363	Peptidase, m42
BCM0060_0816	COG3938	Belongs to the proline racemase family
BCM0060_0820	COG0601	transmembrane transport
BCM0060_0821	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0060_0822	COG0444	Belongs to the ABC transporter superfamily
BCM0060_0823	COG4608	Belongs to the ABC transporter superfamily
BCM0060_0832	COG0477	Major facilitator Superfamily
BCM0060_0833	COG3290	protein histidine kinase activity
BCM0060_0834	COG4565	transcriptional regulatory protein
BCM0060_0835	COG3181	Tripartite tricarboxylate transporter family receptor
BCM0060_0847	COG0305	Participates in initiation and elongation during chromosome replication
BCM0060_0852	COG0477	Major facilitator Superfamily
BCM0060_0864	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0060_0864	COG3320	Male sterility
BCM0060_0865	COG1309	transcriptional regulator
BCM0060_0868	COG1183	phosphatidylcholine synthase activity
BCM0060_0874	COG2376	Dihydroxyacetone kinase
BCM0060_0876	COG2376	Dihydroxyacetone kinase
BCM0060_0877	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCM0060_0878	COG1959	2 iron, 2 sulfur cluster binding
BCM0060_0881	COG0457	Tetratricopeptide repeat
BCM0060_0884	COG2770	Histidine kinase
BCM0060_0884	COG3437	response regulator, receiver
BCM0060_0899	COG1191	sigma factor activity
BCM0060_0901	COG2208	phosphoserine phosphatase activity
BCM0060_0902	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCM0060_0903	COG2198	Histidine kinase
BCM0060_0903	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0060_0903	COG2205	protein histidine kinase activity
BCM0060_0903	COG0784	Response regulator, receiver
BCM0060_0916	COG0420	3'-5' exonuclease activity
BCM0060_0917	COG4717	serine-type aminopeptidase activity
BCM0060_0923	COG0346	lactoylglutathione lyase activity
BCM0060_0924	COG0346	lactoylglutathione lyase activity
BCM0060_0925	COG0457	Tetratricopeptide repeat
BCM0060_0927	COG2267	carboxylic ester hydrolase activity
BCM0060_0931	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCM0060_0932	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCM0060_0934	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCM0060_0935	COG2963	transposase activity
BCM0060_0936	COG2801	Transposase and inactivated derivatives
BCM0060_0948	COG0477	Major facilitator Superfamily
BCM0060_0949	COG0477	Major facilitator Superfamily
BCM0060_0951	COG3973	AAA domain
BCM0060_0952	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0060_0956	COG4980	gas vesicle protein
BCM0060_0957	COG0537	adenosine 5'-monophosphoramidase activity
BCM0060_0958	COG1131	(ABC) transporter
BCM0060_0959	COG4473	ABC transporter
BCM0060_0973	COG1309	transcriptional regulator
BCM0060_0975	COG3402	PFAM membrane-flanked domain
BCM0060_0976	COG3428	Bacterial PH domain
BCM0060_0984	COG3402	PFAM membrane-flanked domain
BCM0060_0985	COG3428	Bacterial PH domain
BCM0060_0986	COG2329	Antibiotic biosynthesis monooxygenase
BCM0060_0987	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0060_0990	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCM0060_0998	COG0675	Transposase, IS605 OrfB family
BCM0060_0999	COG1309	transcriptional regulator
BCM0060_1000	COG1511	domain protein
BCM0060_1003	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_1004	COG1609	Transcriptional regulator
BCM0060_1006	COG1234	tRNA 3'-trailer cleavage
BCM0060_1007	COG0095	Lipoate-protein ligase
BCM0060_1010	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_1017	COG1408	metallophosphoesterase
BCM0060_1020	COG1078	dGTPase activity
BCM0060_1022	COG0477	Major facilitator Superfamily
BCM0060_1024	COG1595	DNA-templated transcription, initiation
BCM0060_1025	COG2207	Transcriptional regulator
BCM0060_1025	COG3708	Transcriptional regulator
BCM0060_1026	COG2205	protein histidine kinase activity
BCM0060_1027	COG0745	RESPONSE REGULATOR receiver
BCM0060_1031	COG0501	Belongs to the peptidase M48B family
BCM0060_1032	COG0697	spore germination
BCM0060_1036	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCM0060_1037	COG2224	Isocitrate lyase
BCM0060_1042	COG4903	ComK protein
BCM0060_1043	COG0398	Pfam SNARE associated Golgi protein
BCM0060_1055	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCM0060_1060	COG0367	asparagine synthase
BCM0060_1061	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCM0060_1062	COG0753	catalase activity
BCM0060_1063	COG0004	ammonium transporteR
BCM0060_1069	COG2996	Protein conserved in bacteria
BCM0060_1070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0060_1072	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_1075	COG0561	phosphatase activity
BCM0060_1077	COG0542	response to heat
BCM0060_1079	COG2267	carboxylic ester hydrolase activity
BCM0060_1082	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_1083	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCM0060_1084	COG5504	Zn-dependent protease
BCM0060_1086	COG0180	Tryptophanyl-tRNA synthetase
BCM0060_1088	COG4166	transmembrane transport
BCM0060_1089	COG0601	transmembrane transport
BCM0060_1090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCM0060_1091	COG0444	Belongs to the ABC transporter superfamily
BCM0060_1092	COG4608	Belongs to the ABC transporter superfamily
BCM0060_1093	COG0534	Mate efflux family protein
BCM0060_1094	COG4166	transmembrane transport
BCM0060_1098	COG0861	Integral membrane protein TerC family
BCM0060_1099	COG4862	establishment of competence for transformation
BCM0060_1100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0060_1102	COG1164	Oligoendopeptidase f
BCM0060_1105	COG2346	COG2346, Truncated hemoglobins
BCM0060_1106	COG4116	CYTH
BCM0060_1108	COG2357	RelA SpoT domain protein
BCM0060_1110	COG0564	pseudouridine synthase activity
BCM0060_1113	COG0772	Belongs to the SEDS family
BCM0060_1114	COG1216	Glycosyl transferase, family 2
BCM0060_1120	COG0457	Tetratricopeptide repeat
BCM0060_1120	COG0463	Glycosyl transferase, family 2
BCM0060_1124	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCM0060_1127	COG1091	dTDP-4-dehydrorhamnose reductase activity
BCM0060_1136	COG2153	protein acetylation
BCM0060_1138	COG2382	esterase
BCM0060_1141	COG5492	domain, Protein
BCM0060_1142	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0060_1144	COG0512	Glutamine amidotransferase of anthranilate synthase
BCM0060_1144	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCM0060_1151	COG1620	l-lactate permease
BCM0060_1152	COG5634	Uncharacterized conserved protein (DUF2278)
BCM0060_1163	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0060_1165	COG1476	TRANSCRIPTIONal
BCM0060_1183	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCM0060_1184	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCM0060_1188	COG4152	abc transporter atp-binding protein
BCM0060_1189	COG1668	transmembrane transport
BCM0060_1213	COG2226	methyltransferase
BCM0060_1215	COG1686	Belongs to the peptidase S11 family
BCM0060_1216	COG0681	Belongs to the peptidase S26 family
BCM0060_1224	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_1226	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCM0060_1227	COG1177	transmembrane transport
BCM0060_1228	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCM0060_1230	COG2409	Drug exporters of the RND superfamily
BCM0060_1232	COG0564	pseudouridine synthase activity
BCM0060_1234	COG2340	Cysteine-rich secretory protein family
BCM0060_1235	COG0247	lactate metabolic process
BCM0060_1236	COG0277	FAD linked oxidase domain protein
BCM0060_1237	COG3835	regulator
BCM0060_1239	COG0745	RESPONSE REGULATOR receiver
BCM0060_1240	COG5002	protein histidine kinase activity
BCM0060_1241	COG2186	Transcriptional regulator
BCM0060_1245	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCM0060_1247	COG2116	formate transmembrane transporter activity
BCM0060_1248	COG0861	Integral membrane protein TerC family
BCM0060_1249	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0060_1251	COG2030	dehydratase
BCM0060_1255	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_1256	COG3243	poly(R)-hydroxyalkanoic acid synthase
BCM0060_1257	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0060_1258	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0060_1261	COG1840	ABC-type Fe3 transport system, periplasmic component
BCM0060_1262	COG3842	ATPase activity
BCM0060_1267	COG1349	DNA-binding transcription factor activity
BCM0060_1271	COG0235	Class ii aldolase
BCM0060_1273	COG2861	carbohydrate metabolic process
BCM0060_1275	COG3852	Histidine kinase
BCM0060_1276	COG1846	Transcriptional regulator
BCM0060_1278	COG2318	DinB family
BCM0060_1279	COG5002	protein histidine kinase activity
BCM0060_1281	COG0720	synthase
BCM0060_1284	COG4873	Protein conserved in bacteria
BCM0060_1290	COG1780	Probably involved in ribonucleotide reductase function
BCM0060_1291	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0060_1292	COG1403	HNH endonuclease
BCM0060_1293	COG1372	Participates in initiation and elongation during chromosome replication
BCM0060_1293	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0060_1294	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCM0060_1295	COG1725	Transcriptional regulator
BCM0060_1296	COG1131	(ABC) transporter
BCM0060_1299	COG1131	(ABC) transporter
BCM0060_1300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0060_1303	COG1522	sequence-specific DNA binding
BCM0060_1305	COG1335	isochorismatase
BCM0060_1307	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0060_1308	COG2070	2-Nitropropane dioxygenase
BCM0060_1309	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCM0060_1311	COG1696	Membrane protein involved in D-alanine export
BCM0060_1316	COG0716	FMN binding
BCM0060_1319	COG3173	Aminoglycoside phosphotransferase
BCM0060_1323	COG0534	Mate efflux family protein
BCM0060_1324	COG1968	undecaprenyl-diphosphatase activity
BCM0060_1327	COG1846	Transcriptional regulator
BCM0060_1329	COG1301	dicarboxylic acid transport
BCM0060_1330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCM0060_1331	COG4709	membrane
BCM0060_1332	COG3874	Sporulation protein YtfJ
BCM0060_1336	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0060_1337	COG0028	Belongs to the TPP enzyme family
BCM0060_1338	COG0440	acetolactate synthase activity
BCM0060_1353	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCM0060_1355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCM0060_1356	COG1183	phosphatidylcholine synthase activity
BCM0060_1357	COG1368	sulfuric ester hydrolase activity
BCM0060_1359	COG0019	diaminopimelate decarboxylase activity
BCM0060_1363	COG0529	Catalyzes the synthesis of activated sulfate
BCM0060_1364	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCM0060_1368	COG1648	precorrin-2 dehydrogenase activity
BCM0060_1369	COG0733	neurotransmitter:sodium symporter activity
BCM0060_1373	COG1757	Na H antiporter
BCM0060_1376	COG4758	membrane
BCM0060_1377	COG4585	Histidine kinase
BCM0060_1378	COG2197	response regulator
BCM0060_1380	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_1382	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCM0060_1390	COG0730	response to heat
BCM0060_1391	COG0306	phosphate transporter
BCM0060_1392	COG1392	Phosphate transport regulator
BCM0060_1393	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0060_1397	COG3852	Histidine kinase
BCM0060_1398	COG1801	Protein of unknown function DUF72
BCM0060_1400	COG0582	viral genome integration into host DNA
BCM0060_1401	COG5002	protein histidine kinase activity
BCM0060_1404	COG0392	lysyltransferase activity
BCM0060_1404	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCM0060_1406	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0060_1407	COG1686	Belongs to the peptidase S11 family
BCM0060_1408	COG2715	membrane protein required for spore maturation
BCM0060_1409	COG0700	Nucleoside recognition
BCM0060_1410	COG1187	pseudouridine synthase activity
BCM0060_1412	COG1333	cytochrome c biogenesis protein
BCM0060_1413	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCM0060_1414	COG0745	RESPONSE REGULATOR receiver
BCM0060_1415	COG5002	protein histidine kinase activity
BCM0060_1416	COG2096	Adenosyltransferase
BCM0060_1417	COG4942	peptidase
BCM0060_1419	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCM0060_1420	COG1141	Ferredoxin
BCM0060_1422	COG0514	ATP-dependent DNA helicase (RecQ)
BCM0060_1423	COG1266	CAAX protease self-immunity
BCM0060_1425	COG1408	metallophosphoesterase
BCM0060_1427	COG4862	establishment of competence for transformation
BCM0060_1428	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCM0060_1432	COG0492	ferredoxin-NADP+ reductase activity
BCM0060_1446	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0060_1449	COG0142	geranyltranstransferase activity
BCM0060_1451	COG0142	geranyltranstransferase activity
BCM0060_1455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCM0060_1456	COG0457	Tetratricopeptide repeat
BCM0060_1460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCM0060_1462	COG4347	Protein of unknown function (DUF1405)
BCM0060_1465	COG2738	Putative neutral zinc metallopeptidase
BCM0060_1467	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_1468	COG1694	Mazg nucleotide pyrophosphohydrolase
BCM0060_1471	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCM0060_1472	COG0438	transferase activity, transferring glycosyl groups
BCM0060_1480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCM0060_1480	COG1199	ATP-dependent helicase activity
BCM0060_1484	COG3935	DnaD domain protein
BCM0060_1485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCM0060_1487	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCM0060_1487	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0060_1498	COG0116	Belongs to the methyltransferase superfamily
BCM0060_1500	COG1199	ATP-dependent helicase activity
BCM0060_1501	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCM0060_1503	COG3173	Aminoglycoside phosphotransferase
BCM0060_1504	COG0024	Methionine aminopeptidase
BCM0060_1506	COG2233	PERMEase
BCM0060_1507	COG2311	Membrane
BCM0060_1509	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0060_1511	COG0456	acetyltransferase
BCM0060_1516	COG0754	glutathionylspermidine amidase activity
BCM0060_1519	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0060_1524	COG0454	-acetyltransferase
BCM0060_1528	COG0328	RNA-DNA hybrid ribonuclease activity
BCM0060_1535	COG3403	YqcI/YcgG family
BCM0060_1536	COG1280	lysine exporter protein (LysE YggA)
BCM0060_1539	COG3162	membrane
BCM0060_1540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0060_1541	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0060_1543	COG0475	glutathione-regulated potassium exporter activity
BCM0060_1544	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0060_1545	COG4978	Transcriptional regulator
BCM0060_1545	COG0789	Transcriptional regulator
BCM0060_1547	COG2323	membrane
BCM0060_1548	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCM0060_1561	COG1923	regulation of RNA biosynthetic process
BCM0060_1563	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCM0060_1564	COG1360	Flagellar Motor Protein
BCM0060_1565	COG2201	protein-glutamate methylesterase activity
BCM0060_1566	COG2198	Histidine kinase
BCM0060_1566	COG0643	Histidine kinase
BCM0060_1567	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0060_1567	COG1776	CheC inhibitor of MCP methylation
BCM0060_1570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCM0060_1574	COG1256	bacterial-type flagellum assembly
BCM0060_1575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCM0060_1576	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCM0060_1579	COG1815	bacterial-type flagellum-dependent cell motility
BCM0060_1580	COG1558	bacterial-type flagellum-dependent cell motility
BCM0060_1582	COG1766	The M ring may be actively involved in energy transduction
BCM0060_1583	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0060_1585	COG1157	protein secretion by the type III secretion system
BCM0060_1592	COG0784	Response regulator, receiver
BCM0060_1592	COG0835	chemotaxis
BCM0060_1596	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCM0060_1597	COG0741	lytic transglycosylase activity
BCM0060_1599	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0060_1600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCM0060_1600	COG1776	CheC inhibitor of MCP methylation
BCM0060_1602	COG1338	Plays a role in the flagellum-specific transport system
BCM0060_1603	COG1987	bacterial-type flagellum assembly
BCM0060_1605	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCM0060_1606	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCM0060_1607	COG1419	protein localization to endoplasmic reticulum
BCM0060_1608	COG4786	Flagellar basal body rod
BCM0060_1609	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCM0060_1619	COG2329	Antibiotic biosynthesis monooxygenase
BCM0060_1624	COG0583	DNA-binding transcription factor activity
BCM0060_1625	COG3842	ATPase activity
BCM0060_1626	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCM0060_1627	COG1178	ABC-type Fe3 transport system permease component
BCM0060_1629	COG1234	tRNA 3'-trailer cleavage
BCM0060_1632	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_1636	COG1686	Belongs to the peptidase S11 family
BCM0060_1638	COG0406	alpha-ribazole phosphatase activity
BCM0060_1641	COG1846	Transcriptional regulator
BCM0060_1643	COG0367	asparagine synthase
BCM0060_1649	COG1802	Transcriptional regulator
BCM0060_1650	COG0697	spore germination
BCM0060_1651	COG0523	cobalamin synthesis protein
BCM0060_1653	COG0701	Predicted permease
BCM0060_1656	COG1757	Na H antiporter
BCM0060_1657	COG0114	fumarate hydratase activity
BCM0060_1662	COG0534	Mate efflux family protein
BCM0060_1663	COG3340	Belongs to the peptidase S51 family
BCM0060_1667	COG0785	Cytochrome C biogenesis protein
BCM0060_1673	COG2733	membrane
BCM0060_1680	COG1131	(ABC) transporter
BCM0060_1683	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0060_1684	COG0528	UMP kinase activity
BCM0060_1686	COG1027	Aspartate ammonia-lyase
BCM0060_1687	COG0281	malic enzyme
BCM0060_1688	COG4191	Histidine kinase
BCM0060_1689	COG0784	Response regulator, receiver
BCM0060_1690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0060_1694	COG3620	sequence-specific DNA binding
BCM0060_1699	COG1051	belongs to the nudix hydrolase family
BCM0060_1704	COG1966	Carbon starvation protein
BCM0060_1706	COG1695	Transcriptional regulator
BCM0060_1708	COG0477	Major facilitator Superfamily
BCM0060_1709	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_1711	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCM0060_1712	COG4166	transmembrane transport
BCM0060_1713	COG2223	nitrite transmembrane transporter activity
BCM0060_1714	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0060_1717	COG2244	polysaccharide biosynthetic process
BCM0060_1718	COG0733	neurotransmitter:sodium symporter activity
BCM0060_1720	COG5566	PFAM Mor transcription activator
BCM0060_1721	COG2323	membrane
BCM0060_1724	COG2084	Dehydrogenase
BCM0060_1727	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0060_1729	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0060_1730	COG0028	Belongs to the TPP enzyme family
BCM0060_1731	COG0440	acetolactate synthase activity
BCM0060_1732	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCM0060_1734	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCM0060_1738	COG2814	Major facilitator Superfamily
BCM0060_1739	COG3384	dioxygenase
BCM0060_1743	COG3279	Response regulator of the LytR AlgR family
BCM0060_1744	COG0427	acetyl-CoA hydrolase
BCM0060_1751	COG4166	transmembrane transport
BCM0060_1756	COG0535	radical SAM domain protein
BCM0060_1757	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_1758	COG0745	RESPONSE REGULATOR receiver
BCM0060_1762	COG1914	H( )-stimulated, divalent metal cation uptake system
BCM0060_1765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCM0060_1767	COG0531	amino acid
BCM0060_1772	COG2390	Transcriptional regulator
BCM0060_1774	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_1775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCM0060_1780	COG0006	proline dipeptidase activity
BCM0060_1781	COG2132	Multicopper oxidase
BCM0060_1785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCM0060_1789	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_1791	COG1276	copper resistance
BCM0060_1791	COG2372	response to copper ion
BCM0060_1792	COG4549	nuclear export factor GLE1
BCM0060_1793	COG0697	spore germination
BCM0060_1794	COG0583	DNA-binding transcription factor activity
BCM0060_1795	COG1959	2 iron, 2 sulfur cluster binding
BCM0060_1796	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCM0060_1797	COG0778	Nitroreductase
BCM0060_1800	COG0628	permease
BCM0060_1802	COG1231	oxidoreductase activity
BCM0060_1803	COG0523	cobalamin synthesis protein
BCM0060_1806	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_1807	COG2030	dehydratase
BCM0060_1808	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_1810	COG0411	ABC transporter
BCM0060_1814	COG0583	DNA-binding transcription factor activity
BCM0060_1816	COG1942	4-Oxalocrotonate Tautomerase
BCM0060_1820	COG1271	oxidase subunit
BCM0060_1821	COG1294	oxidase, subunit
BCM0060_1822	COG4988	ABC transporter
BCM0060_1823	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCM0060_1826	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0060_1827	COG1686	Belongs to the peptidase S11 family
BCM0060_1830	COG1388	LysM domain
BCM0060_1830	COG0791	NLP P60 protein
BCM0060_1832	COG1132	(ABC) transporter
BCM0060_1833	COG0745	RESPONSE REGULATOR receiver
BCM0060_1834	COG2205	protein histidine kinase activity
BCM0060_1836	COG0300	oxidoreductase activity
BCM0060_1837	COG4122	O-methyltransferase activity
BCM0060_1844	COG0460	homoserine dehydrogenase
BCM0060_1849	COG1316	TRANSCRIPTIONal
BCM0060_1851	COG0745	RESPONSE REGULATOR receiver
BCM0060_1852	COG5002	protein histidine kinase activity
BCM0060_1855	COG1285	pathogenesis
BCM0060_1856	COG1247	-acetyltransferase
BCM0060_1860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0060_1862	COG1082	Xylose isomerase domain protein TIM barrel
BCM0060_1864	COG2814	Major facilitator Superfamily
BCM0060_1865	COG1279	arginine transmembrane transporter activity
BCM0060_1866	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_1868	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCM0060_1875	COG0577	efflux transmembrane transporter activity
BCM0060_1876	COG2002	toxin-antitoxin pair type II binding
BCM0060_1877	COG1404	Belongs to the peptidase S8 family
BCM0060_1878	COG0640	Transcriptional regulator
BCM0060_1879	COG0667	Aldo Keto reductase
BCM0060_1880	COG2814	Major facilitator Superfamily
BCM0060_1885	COG0840	transmembrane signaling receptor activity
BCM0060_1888	COG3949	Membrane
BCM0060_1889	COG0783	Belongs to the Dps family
BCM0060_1892	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCM0060_1894	COG1231	oxidoreductase activity
BCM0060_1895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_1896	COG4989	oxidoreductase activity
BCM0060_1897	COG0523	cobalamin synthesis protein
BCM0060_1898	COG0456	acetyltransferase
BCM0060_1902	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCM0060_1902	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCM0060_1904	COG0702	epimerase
BCM0060_1906	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCM0060_1908	COG4166	transmembrane transport
BCM0060_1911	COG0406	alpha-ribazole phosphatase activity
BCM0060_1913	COG5337	Spore coat protein CotH
BCM0060_1914	COG1051	belongs to the nudix hydrolase family
BCM0060_1915	COG0586	Pfam SNARE associated Golgi protein
BCM0060_1916	COG2244	polysaccharide biosynthetic process
BCM0060_1918	COG0701	Predicted permease
BCM0060_1919	COG3689	TIGRFAM TIGR03943 family protein
BCM0060_1920	COG1607	acyl-coa hydrolase
BCM0060_1921	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0060_1924	COG0702	epimerase
BCM0060_1925	COG2839	Protein conserved in bacteria
BCM0060_1926	COG1253	flavin adenine dinucleotide binding
BCM0060_1929	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_1930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0060_1933	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0060_1935	COG1876	peptidase activity
BCM0060_1938	COG2211	Major facilitator Superfamily
BCM0060_1942	COG2368	4-hydroxyphenylacetate
BCM0060_1944	COG0196	riboflavin kinase activity
BCM0060_1947	COG0251	oxidation-reduction process
BCM0060_1949	COG3971	2-oxopent-4-enoate hydratase activity
BCM0060_1953	COG1942	4-Oxalocrotonate Tautomerase
BCM0060_1955	COG0561	phosphatase activity
BCM0060_1957	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCM0060_1958	COG4106	trans-aconitate 2-methyltransferase activity
BCM0060_1961	COG1819	glycosyl
BCM0060_1962	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_1963	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_1969	COG0456	acetyltransferase
BCM0060_1987	COG3874	Sporulation protein YtfJ
BCM0060_1992	COG2226	methyltransferase
BCM0060_1996	COG1082	Xylose isomerase domain protein TIM barrel
BCM0060_1997	COG0346	lactoylglutathione lyase activity
BCM0060_1999	COG0604	alcohol dehydrogenase
BCM0060_2000	COG1595	DNA-templated transcription, initiation
BCM0060_2003	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCM0060_2003	COG0426	domain, Protein
BCM0060_2005	COG0386	Belongs to the glutathione peroxidase family
BCM0060_2006	COG1305	Transglutaminase-like
BCM0060_2007	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BCM0060_2008	COG0714	Associated with various cellular activities
BCM0060_2012	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCM0060_2013	COG1140	nitrate reductase beta subunit
BCM0060_2014	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCM0060_2015	COG2181	nitrate reductase activity
BCM0060_2016	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCM0060_2017	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCM0060_2018	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0060_2019	COG0303	'Molybdopterin
BCM0060_2020	COG0314	molybdopterin synthase activity
BCM0060_2022	COG2223	nitrite transmembrane transporter activity
BCM0060_2024	COG1648	precorrin-2 dehydrogenase activity
BCM0060_2026	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCM0060_2026	COG1587	Uroporphyrinogen-III synthase
BCM0060_2027	COG2146	nitrite reductase [NAD(P)H] activity
BCM0060_2028	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCM0060_2029	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BCM0060_2034	COG2359	stage V sporulation protein S
BCM0060_2043	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0060_2048	COG1418	mRNA catabolic process
BCM0060_2049	COG0488	(ABC) transporter
BCM0060_2052	COG0629	single-stranded DNA binding
BCM0060_2055	COG1413	lyase activity
BCM0060_2058	COG2521	methyltransferase
BCM0060_2058	COG2136	Putative SAM-dependent methyltransferase
BCM0060_2066	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCM0060_2067	COG0017	Asparaginyl-tRNA synthetase
BCM0060_2071	COG1674	ftsk spoiiie
BCM0060_2080	COG1929	Belongs to the glycerate kinase type-1 family
BCM0060_2081	COG0471	metal ion transport
BCM0060_2082	COG0745	RESPONSE REGULATOR receiver
BCM0060_2083	COG3850	Histidine kinase
BCM0060_2083	COG5002	protein histidine kinase activity
BCM0060_2086	COG0733	neurotransmitter:sodium symporter activity
BCM0060_2087	COG0733	neurotransmitter:sodium symporter activity
BCM0060_2093	COG2610	gluconate transmembrane transporter activity
BCM0060_2094	COG1454	alcohol dehydrogenase
BCM0060_2095	COG1794	racemase activity, acting on amino acids and derivatives
BCM0060_2097	COG0456	acetyltransferase
BCM0060_2098	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCM0060_2100	COG1131	(ABC) transporter
BCM0060_2101	COG4473	ABC transporter
BCM0060_2103	COG0546	phosphoglycolate phosphatase activity
BCM0060_2107	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0060_2108	COG3250	beta-galactosidase activity
BCM0060_2111	COG0768	penicillin binding
BCM0060_2113	COG0204	Acyl-transferase
BCM0060_2114	COG1272	protein, Hemolysin III
BCM0060_2116	COG0805	protein transport
BCM0060_2118	COG1307	EDD domain protein, DegV family
BCM0060_2119	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCM0060_2120	COG1999	signal sequence binding
BCM0060_2121	COG0071	Belongs to the small heat shock protein (HSP20) family
BCM0060_2122	COG0367	asparagine synthase
BCM0060_2125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_2126	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCM0060_2130	COG1335	isochorismatase
BCM0060_2131	COG1051	belongs to the nudix hydrolase family
BCM0060_2133	COG0668	transmembrane transport
BCM0060_2134	COG2203	Gaf domain
BCM0060_2134	COG4585	Histidine kinase
BCM0060_2135	COG2197	response regulator
BCM0060_2136	COG1737	Transcriptional regulator
BCM0060_2137	COG1064	alcohol dehydrogenase
BCM0060_2142	COG1070	Carbohydrate kinase
BCM0060_2143	COG1070	Carbohydrate kinase
BCM0060_2149	COG0517	IMP dehydrogenase activity
BCM0060_2149	COG1125	glycine betaine transport
BCM0060_2150	COG1174	glycine betaine transport
BCM0060_2158	COG1253	flavin adenine dinucleotide binding
BCM0060_2159	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_2160	COG5506	Protein of unknown function (DUF1694)
BCM0060_2163	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0060_2164	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BCM0060_2165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCM0060_2166	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0060_2167	COG0456	acetyltransferase
BCM0060_2168	COG3829	transcription factor binding
BCM0060_2169	COG1509	lysine 2,3-aminomutase activity
BCM0060_2176	COG3064	Membrane
BCM0060_2176	COG4991	sh3 domain protein
BCM0060_2176	COG0515	serine threonine protein kinase
BCM0060_2177	COG4326	sporulation control protein
BCM0060_2178	COG0671	phosphoesterase, PA-phosphatase related
BCM0060_2179	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCM0060_2180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0060_2193	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCM0060_2200	COG0300	oxidoreductase activity
BCM0060_2204	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCM0060_2204	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0060_2206	COG2814	Major facilitator Superfamily
BCM0060_2207	COG4841	protein insertion into membrane
BCM0060_2208	COG0372	Belongs to the citrate synthase family
BCM0060_2209	COG2079	MmgE PrpD family protein
BCM0060_2210	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCM0060_2211	COG1960	acyl-CoA dehydrogenase activity
BCM0060_2212	COG2084	Dehydrogenase
BCM0060_2214	COG1280	lysine exporter protein (LysE YggA)
BCM0060_2215	COG1024	Enoyl-CoA hydratase
BCM0060_2218	COG0420	3'-5' exonuclease activity
BCM0060_2219	COG0419	ATPase involved in DNA repair
BCM0060_2223	COG2223	nitrite transmembrane transporter activity
BCM0060_2224	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_2225	COG1169	isochorismate synthase
BCM0060_2226	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCM0060_2227	COG1535	isochorismatase
BCM0060_2227	COG3433	isochorismatase activity
BCM0060_2228	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCM0060_2229	COG3251	PFAM MbtH domain protein
BCM0060_2230	COG2814	Major facilitator Superfamily
BCM0060_2233	COG0776	regulation of translation
BCM0060_2235	COG2318	DinB family
BCM0060_2237	COG1115	amino acid carrier protein
BCM0060_2240	COG2329	Antibiotic biosynthesis monooxygenase
BCM0060_2241	COG1187	pseudouridine synthase activity
BCM0060_2242	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCM0060_2243	COG1136	(ABC) transporter
BCM0060_2245	COG0596	Alpha beta hydrolase
BCM0060_2246	COG2814	Major facilitator Superfamily
BCM0060_2250	COG2226	methyltransferase
BCM0060_2260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_2267	COG1247	-acetyltransferase
BCM0060_2273	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCM0060_2275	COG2226	methyltransferase
BCM0060_2276	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_2278	COG1278	Cold shock
BCM0060_2281	COG0010	Belongs to the arginase family
BCM0060_2283	COG0583	DNA-binding transcription factor activity
BCM0060_2284	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCM0060_2287	COG0583	DNA-binding transcription factor activity
BCM0060_2288	COG2258	MOSC domain
BCM0060_2292	COG1132	(ABC) transporter
BCM0060_2293	COG1132	(ABC) transporter
BCM0060_2297	COG1396	sequence-specific DNA binding
BCM0060_2304	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCM0060_2306	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BCM0060_2307	COG1595	DNA-templated transcription, initiation
BCM0060_2312	COG1649	PFAM Uncharacterised BCR, COG1649
BCM0060_2317	COG2971	BadF BadG BcrA BcrD
BCM0060_2319	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCM0060_2326	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_2333	COG1309	transcriptional regulator
BCM0060_2336	COG0577	efflux transmembrane transporter activity
BCM0060_2336	COG1136	(ABC) transporter
BCM0060_2337	COG0500	methyltransferase
BCM0060_2337	COG3615	Tellurite resistance protein tehB
BCM0060_2339	COG2226	methyltransferase
BCM0060_2340	COG3961	Belongs to the TPP enzyme family
BCM0060_2341	COG1846	Transcriptional regulator
BCM0060_2351	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCM0060_2353	COG0110	maltose O-acetyltransferase activity
BCM0060_2355	COG1686	Belongs to the peptidase S11 family
BCM0060_2357	COG0768	penicillin binding
BCM0060_2358	COG1595	DNA-templated transcription, initiation
BCM0060_2361	COG0768	penicillin binding
BCM0060_2362	COG2367	Beta-lactamase
BCM0060_2363	COG1408	metallophosphoesterase
BCM0060_2364	COG0675	Transposase, IS605 OrfB family
BCM0060_2368	COG1960	acyl-CoA dehydrogenase activity
BCM0060_2369	COG0439	Biotin carboxylase
BCM0060_2370	COG0511	ligase activity, forming carbon-carbon bonds
BCM0060_2371	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCM0060_2372	COG1024	Enoyl-CoA hydratase
BCM0060_2373	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCM0060_2374	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0060_2376	COG1247	-acetyltransferase
BCM0060_2377	COG0572	uridine kinase
BCM0060_2379	COG2318	DinB family
BCM0060_2385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCM0060_2389	COG3227	Zinc metalloprotease (Elastase)
BCM0060_2393	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCM0060_2393	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCM0060_2406	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_2410	COG1063	alcohol dehydrogenase
BCM0060_2414	COG3386	PFAM SMP-30 Gluconolaconase
BCM0060_2416	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BCM0060_2417	COG3773	Cell wall hydrolase
BCM0060_2419	COG0745	RESPONSE REGULATOR receiver
BCM0060_2420	COG2205	protein histidine kinase activity
BCM0060_2422	COG0488	(ABC) transporter
BCM0060_2424	COG1136	(ABC) transporter
BCM0060_2425	COG0577	efflux transmembrane transporter activity
BCM0060_2429	COG0460	homoserine dehydrogenase
BCM0060_2430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_2432	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCM0060_2452	COG2124	cytochrome p450
BCM0060_2460	COG0561	phosphatase activity
BCM0060_2463	COG2814	Major facilitator Superfamily
BCM0060_2468	COG5002	protein histidine kinase activity
BCM0060_2469	COG0768	penicillin binding
BCM0060_2470	COG1819	glycosyl
BCM0060_2471	COG1794	racemase activity, acting on amino acids and derivatives
BCM0060_2475	COG2205	protein histidine kinase activity
BCM0060_2477	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0060_2478	COG0604	alcohol dehydrogenase
BCM0060_2479	COG0671	phosphoesterase, PA-phosphatase related
BCM0060_2480	COG0768	penicillin binding
BCM0060_2482	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_2484	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0060_2491	COG0693	protein deglycase activity
BCM0060_2492	COG0693	protein deglycase activity
BCM0060_2495	COG2814	Major facilitator Superfamily
BCM0060_2499	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0060_2503	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_2504	COG0697	spore germination
BCM0060_2509	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0060_2511	COG2223	nitrite transmembrane transporter activity
BCM0060_2512	COG2816	NAD+ diphosphatase activity
BCM0060_2513	COG0592	DNA-directed DNA polymerase activity
BCM0060_2514	COG1051	belongs to the nudix hydrolase family
BCM0060_2519	COG0406	alpha-ribazole phosphatase activity
BCM0060_2521	COG3878	Protein conserved in bacteria
BCM0060_2522	COG3878	Protein conserved in bacteria
BCM0060_2526	COG4667	esterase of the alpha-beta hydrolase superfamily
BCM0060_2532	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCM0060_2535	COG0322	excinuclease ABC activity
BCM0060_2543	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0060_2548	COG1011	Hydrolase
BCM0060_2552	COG1523	belongs to the glycosyl hydrolase 13 family
BCM0060_2553	COG3227	Zinc metalloprotease (Elastase)
BCM0060_2557	COG0346	lactoylglutathione lyase activity
BCM0060_2558	COG0201	protein transport
BCM0060_2560	COG0697	spore germination
BCM0060_2561	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_2568	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_2571	COG2959	enzyme of heme biosynthesis
BCM0060_2578	COG1309	transcriptional regulator
BCM0060_2583	COG3284	Transcriptional regulator
BCM0060_2586	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_2587	COG1349	DNA-binding transcription factor activity
BCM0060_2591	COG1959	2 iron, 2 sulfur cluster binding
BCM0060_2594	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCM0060_2595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0060_2596	COG0022	dehydrogenase e1 component
BCM0060_2597	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0060_2599	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_2600	COG0456	acetyltransferase
BCM0060_2600	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0060_2601	COG0572	uridine kinase
BCM0060_2604	COG0494	nUDIX hydrolase
BCM0060_2609	COG4176	ABC-type proline glycine betaine transport system permease component
BCM0060_2610	COG0517	IMP dehydrogenase activity
BCM0060_2610	COG4175	Glycine betaine
BCM0060_2616	COG2153	protein acetylation
BCM0060_2617	COG3397	chitin binding
BCM0060_2619	COG2205	protein histidine kinase activity
BCM0060_2620	COG2226	methyltransferase
BCM0060_2621	COG2315	Protein conserved in bacteria
BCM0060_2622	COG2153	protein acetylation
BCM0060_2623	COG2333	competence protein COMEC
BCM0060_2623	COG0658	competence protein
BCM0060_2633	COG3973	AAA domain
BCM0060_2637	COG0514	ATP-dependent DNA helicase (RecQ)
BCM0060_2642	COG4637	Psort location Cytoplasmic, score
BCM0060_2647	COG3397	chitin binding
BCM0060_2649	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCM0060_2650	COG1115	amino acid carrier protein
BCM0060_2651	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_2652	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCM0060_2654	COG3938	Belongs to the proline racemase family
BCM0060_2655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCM0060_2663	COG0586	Pfam SNARE associated Golgi protein
BCM0060_2666	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCM0060_2667	COG0519	Catalyzes the synthesis of GMP from XMP
BCM0060_2668	COG4166	transmembrane transport
BCM0060_2670	COG4948	Mandelate Racemase Muconate Lactonizing
BCM0060_2678	COG2936	dipeptidyl-peptidase activity
BCM0060_2679	COG5002	protein histidine kinase activity
BCM0060_2680	COG0745	RESPONSE REGULATOR receiver
BCM0060_2686	COG1164	Oligoendopeptidase f
BCM0060_2687	COG0531	amino acid
BCM0060_2688	COG1522	sequence-specific DNA binding
BCM0060_2689	COG1307	EDD domain protein, DegV family
BCM0060_2693	COG2814	Major facilitator Superfamily
BCM0060_2695	COG1664	Polymer-forming cytoskeletal
BCM0060_2696	COG0789	Transcriptional regulator
BCM0060_2697	COG4533	DNA binding
BCM0060_2698	COG2814	Major facilitator Superfamily
BCM0060_2698	COG0477	Major facilitator Superfamily
BCM0060_2702	COG2261	transglycosylase associated protein
BCM0060_2706	COG2226	methyltransferase
BCM0060_2712	COG0436	Aminotransferase
BCM0060_2713	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCM0060_2714	COG5146	pantothenate kinase activity
BCM0060_2715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCM0060_2718	COG1131	(ABC) transporter
BCM0060_2727	COG0628	permease
BCM0060_2729	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCM0060_2730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0060_2731	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0060_2734	COG2816	NAD+ diphosphatase activity
BCM0060_2738	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCM0060_2743	COG0697	spore germination
BCM0060_2744	COG2318	DinB family
BCM0060_2752	COG0861	Integral membrane protein TerC family
BCM0060_2753	COG1368	sulfuric ester hydrolase activity
BCM0060_2754	COG0488	(ABC) transporter
BCM0060_2756	COG1033	growth of symbiont in host cell
BCM0060_2756	COG2409	Drug exporters of the RND superfamily
BCM0060_2757	COG1309	transcriptional regulator
BCM0060_2760	COG0287	Prephenate dehydrogenase
BCM0060_2761	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCM0060_2763	COG1605	Chorismate mutase
BCM0060_2763	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCM0060_2771	COG3584	3D domain protein
BCM0060_2771	COG1388	LysM domain
BCM0060_2773	COG2610	gluconate transmembrane transporter activity
BCM0060_2774	COG1024	Enoyl-CoA hydratase
BCM0060_2776	COG3829	transcription factor binding
BCM0060_2776	COG3290	protein histidine kinase activity
BCM0060_2780	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCM0060_2781	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCM0060_2783	COG2390	Transcriptional regulator
BCM0060_2784	COG1070	Carbohydrate kinase
BCM0060_2791	COG2329	Antibiotic biosynthesis monooxygenase
BCM0060_2795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_2798	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0060_2799	COG4187	Peptidase family M20/M25/M40
BCM0060_2800	COG1414	Transcriptional regulator
BCM0060_2801	COG0833	amino acid
BCM0060_2804	COG0833	amino acid
BCM0060_2805	COG1690	Belongs to the RtcB family
BCM0060_2806	COG3239	Fatty acid desaturase
BCM0060_2807	COG1785	Belongs to the alkaline phosphatase family
BCM0060_2809	COG3655	Transcriptional regulator
BCM0060_2812	COG4377	Putative membrane peptidase family (DUF2324)
BCM0060_2814	COG3279	Response regulator of the LytR AlgR family
BCM0060_2819	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_2820	COG0346	lactoylglutathione lyase activity
BCM0060_2824	COG0714	Associated with various cellular activities
BCM0060_2833	COG0463	Glycosyl transferase, family 2
BCM0060_2835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCM0060_2836	COG0753	catalase activity
BCM0060_2838	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BCM0060_2844	COG0778	Nitroreductase
BCM0060_2845	COG1846	Transcriptional regulator
BCM0060_2852	COG1725	Transcriptional regulator
BCM0060_2855	COG0577	efflux transmembrane transporter activity
BCM0060_2855	COG1136	(ABC) transporter
BCM0060_2860	COG2207	Transcriptional regulator
BCM0060_2861	COG0456	acetyltransferase
BCM0060_2865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_2873	COG0730	response to heat
BCM0060_2875	COG0833	amino acid
BCM0060_2877	COG4335	DNA alkylation repair
BCM0060_2883	COG0768	penicillin binding
BCM0060_2890	COG1984	allophanate hydrolase subunit 2
BCM0060_2891	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCM0060_2892	COG1414	Transcriptional regulator
BCM0060_2894	COG3142	Participates in the control of copper homeostasis
BCM0060_2895	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0060_2896	COG0640	Transcriptional regulator
BCM0060_2898	COG1960	acyl-CoA dehydrogenase activity
BCM0060_2901	COG3314	Sporulation integral membrane protein YlbJ
BCM0060_2907	COG0574	Belongs to the PEP-utilizing enzyme family
BCM0060_2907	COG3848	Pyruvate phosphate dikinase
BCM0060_2909	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_2913	COG5577	PFAM Coat F domain
BCM0060_2914	COG3403	YqcI/YcgG family
BCM0060_2915	COG1280	lysine exporter protein (LysE YggA)
BCM0060_2916	COG1113	amino acid transport
BCM0060_2922	COG1063	alcohol dehydrogenase
BCM0060_2925	COG4977	sequence-specific DNA binding
BCM0060_2927	COG4974	Belongs to the 'phage' integrase family
BCM0060_2930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0060_2932	COG0737	Belongs to the 5'-nucleotidase family
BCM0060_2936	COG3344	reverse transcriptase
BCM0060_2937	COG2329	Antibiotic biosynthesis monooxygenase
BCM0060_2939	COG0598	Magnesium transport protein CorA
BCM0060_2946	COG0415	Belongs to the DNA photolyase family
BCM0060_2947	COG0288	reversible hydration of carbon dioxide
BCM0060_2949	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCM0060_2950	COG5609	conserved protein (DUF2294)
BCM0060_2953	COG0714	Associated with various cellular activities
BCM0060_2954	COG1575	Belongs to the MenA family. Type 1 subfamily
BCM0060_2955	COG2267	carboxylic ester hydrolase activity
BCM0060_2956	COG4641	Protein conserved in bacteria
BCM0060_2957	COG1136	(ABC) transporter
BCM0060_2958	COG0577	efflux transmembrane transporter activity
BCM0060_2962	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCM0060_2963	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCM0060_2964	COG1121	(ABC) transporter
BCM0060_2970	COG0798	PFAM Bile acid sodium symporter
BCM0060_2971	COG0346	lactoylglutathione lyase activity
BCM0060_2972	COG0640	Transcriptional regulator
BCM0060_2975	COG0443	Heat shock 70 kDa protein
BCM0060_2979	COG0346	lactoylglutathione lyase activity
BCM0060_2988	COG2814	Major facilitator Superfamily
BCM0060_2993	COG0745	RESPONSE REGULATOR receiver
BCM0060_2994	COG3850	Histidine kinase
BCM0060_2994	COG5002	protein histidine kinase activity
BCM0060_3001	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BCM0060_3006	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_3007	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCM0060_3009	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_3012	COG2309	aminopeptidase activity
BCM0060_3014	COG0789	Transcriptional regulator
BCM0060_3015	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BCM0060_3019	COG0577	efflux transmembrane transporter activity
BCM0060_3023	COG5002	protein histidine kinase activity
BCM0060_3023	COG3850	Histidine kinase
BCM0060_3025	COG2364	Membrane
BCM0060_3027	COG1846	Transcriptional regulator
BCM0060_3028	COG0456	acetyltransferase
BCM0060_3029	COG2808	Putative FMN-binding domain
BCM0060_3030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_3031	COG2271	Major facilitator Superfamily
BCM0060_3032	COG1556	Lactate utilization protein
BCM0060_3033	COG1139	Iron-sulfur cluster binding protein
BCM0060_3035	COG0583	DNA-binding transcription factor activity
BCM0060_3039	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0060_3042	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCM0060_3046	COG1595	DNA-templated transcription, initiation
BCM0060_3049	COG0662	Cupin 2, conserved barrel domain protein
BCM0060_3050	COG2207	Transcriptional regulator
BCM0060_3050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_3057	COG3409	Peptidoglycan-binding domain 1 protein
BCM0060_3057	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0060_3065	COG0477	Major facilitator Superfamily
BCM0060_3067	COG1846	Transcriptional regulator
BCM0060_3068	COG2814	Major facilitator Superfamily
BCM0060_3071	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0060_3072	COG1131	(ABC) transporter
BCM0060_3076	COG2076	Multidrug Resistance protein
BCM0060_3077	COG1309	transcriptional regulator
BCM0060_3081	COG2031	fatty acid transporter
BCM0060_3083	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0060_3089	COG1122	ATPase activity
BCM0060_3090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCM0060_3093	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCM0060_3094	COG1288	antiporter activity
BCM0060_3095	COG2356	endonuclease I
BCM0060_3096	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCM0060_3100	COG3620	sequence-specific DNA binding
BCM0060_3101	COG2819	hydrolase of the alpha beta superfamily
BCM0060_3102	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCM0060_3106	COG1733	regulation of RNA biosynthetic process
BCM0060_3107	COG0778	Nitroreductase
BCM0060_3113	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3115	COG1131	(ABC) transporter
BCM0060_3123	COG1011	Hydrolase
BCM0060_3128	COG2365	Tyrosine phosphatase family
BCM0060_3133	COG0346	lactoylglutathione lyase activity
BCM0060_3134	COG1940	carbohydrate kinase activity
BCM0060_3135	COG0110	maltose O-acetyltransferase activity
BCM0060_3136	COG0628	permease
BCM0060_3140	COG2226	methyltransferase
BCM0060_3142	COG0477	Major facilitator Superfamily
BCM0060_3148	COG1253	flavin adenine dinucleotide binding
BCM0060_3149	COG0789	Transcriptional regulator
BCM0060_3150	COG0697	spore germination
BCM0060_3151	COG1357	PFAM Pentapeptide repeats (8 copies)
BCM0060_3152	COG3813	Protein conserved in bacteria
BCM0060_3153	COG2706	6-phosphogluconolactonase activity
BCM0060_3154	COG1070	Carbohydrate kinase
BCM0060_3156	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCM0060_3157	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCM0060_3159	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCM0060_3166	COG0814	amino acid
BCM0060_3171	COG1393	Belongs to the ArsC family
BCM0060_3173	COG2188	Transcriptional regulator
BCM0060_3174	COG0673	inositol 2-dehydrogenase activity
BCM0060_3177	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_3181	COG0384	phenazine biosynthesis protein PhzF
BCM0060_3184	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_3185	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0060_3186	COG1733	regulation of RNA biosynthetic process
BCM0060_3190	COG1191	sigma factor activity
BCM0060_3192	COG1266	CAAX protease self-immunity
BCM0060_3193	COG1309	transcriptional regulator
BCM0060_3197	COG3152	Membrane
BCM0060_3207	COG1151	hydroxylamine reductase activity
BCM0060_3209	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_3210	COG3757	hydrolase, family 25
BCM0060_3210	COG3409	Peptidoglycan-binding domain 1 protein
BCM0060_3217	COG2072	flavoprotein involved in K transport
BCM0060_3224	COG0604	alcohol dehydrogenase
BCM0060_3225	COG0604	alcohol dehydrogenase
BCM0060_3226	COG1113	amino acid transport
BCM0060_3227	COG2814	Major facilitator Superfamily
BCM0060_3231	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3232	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3234	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCM0060_3235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0060_3238	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_3239	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_3240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_3241	COG3739	integral membrane protein
BCM0060_3242	COG0384	phenazine biosynthesis protein PhzF
BCM0060_3246	COG0583	DNA-binding transcription factor activity
BCM0060_3250	COG1193	negative regulation of DNA recombination
BCM0060_3254	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCM0060_3255	COG1164	Oligoendopeptidase f
BCM0060_3256	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCM0060_3262	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0060_3267	COG0640	Transcriptional regulator
BCM0060_3268	COG0604	alcohol dehydrogenase
BCM0060_3270	COG0457	Tetratricopeptide repeat
BCM0060_3272	COG2808	Putative FMN-binding domain
BCM0060_3273	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0060_3275	COG0385	Bile acid
BCM0060_3276	COG0277	FAD linked oxidase domain protein
BCM0060_3282	COG1216	Glycosyl transferase, family 2
BCM0060_3283	COG1024	Enoyl-CoA hydratase
BCM0060_3285	COG1285	pathogenesis
BCM0060_3288	COG2514	catechol 2,3-dioxygenase activity
BCM0060_3289	COG2720	vancomycin resistance protein
BCM0060_3297	COG0716	FMN binding
BCM0060_3303	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3305	COG0165	Argininosuccinate lyase
BCM0060_3308	COG4145	pantothenate transmembrane transporter activity
BCM0060_3310	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_3311	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3313	COG1657	PFAM Prenyltransferase squalene oxidase
BCM0060_3314	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCM0060_3315	COG2962	Rard protein
BCM0060_3316	COG3326	Membrane
BCM0060_3319	COG0489	protein tyrosine kinase activity
BCM0060_3321	COG0314	molybdopterin synthase activity
BCM0060_3322	COG0303	'Molybdopterin
BCM0060_3323	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0060_3324	COG2116	formate transmembrane transporter activity
BCM0060_3326	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCM0060_3327	COG5609	conserved protein (DUF2294)
BCM0060_3328	COG2427	Protein of unknown function (DUF1641)
BCM0060_3329	COG3383	formate dehydrogenase (NAD+) activity
BCM0060_3330	COG0697	spore germination
BCM0060_3338	COG2226	methyltransferase
BCM0060_3339	COG4166	transmembrane transport
BCM0060_3340	COG4166	transmembrane transport
BCM0060_3341	COG4166	transmembrane transport
BCM0060_3342	COG1301	dicarboxylic acid transport
BCM0060_3343	COG1316	TRANSCRIPTIONal
BCM0060_3345	COG1595	DNA-templated transcription, initiation
BCM0060_3349	COG1131	(ABC) transporter
BCM0060_3355	COG0673	inositol 2-dehydrogenase activity
BCM0060_3357	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCM0060_3358	COG0187	DNA topoisomerase II activity
BCM0060_3359	COG1832	CoA-binding protein
BCM0060_3360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0060_3361	COG0745	RESPONSE REGULATOR receiver
BCM0060_3365	COG4841	protein insertion into membrane
BCM0060_3366	COG0824	Thioesterase
BCM0060_3372	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0060_3374	COG1132	(ABC) transporter
BCM0060_3375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCM0060_3381	COG2211	Major facilitator Superfamily
BCM0060_3383	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCM0060_3386	COG0183	Belongs to the thiolase family
BCM0060_3387	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_3388	COG1268	BioY protein
BCM0060_3389	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_3399	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_3401	COG5002	protein histidine kinase activity
BCM0060_3402	COG0400	carboxylic ester hydrolase activity
BCM0060_3403	COG0346	lactoylglutathione lyase activity
BCM0060_3404	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCM0060_3405	COG0069	glutamate synthase activity
BCM0060_3407	COG1329	Transcriptional regulator
BCM0060_3408	COG0010	Belongs to the arginase family
BCM0060_3413	COG2226	methyltransferase
BCM0060_3421	COG3344	reverse transcriptase
BCM0060_3424	COG4846	Membrane protein involved in cytochrome C biogenesis
BCM0060_3425	COG0785	Cytochrome C biogenesis protein
BCM0060_3427	COG1473	amidohydrolase
BCM0060_3429	COG1131	(ABC) transporter
BCM0060_3431	COG0583	DNA-binding transcription factor activity
BCM0060_3433	COG1346	cytolysis
BCM0060_3436	COG0730	response to heat
BCM0060_3438	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0060_3438	COG3409	Peptidoglycan-binding domain 1 protein
BCM0060_3441	COG1132	(ABC) transporter
BCM0060_3442	COG1132	(ABC) transporter
BCM0060_3463	COG3639	organic phosphonate transmembrane transporter activity
BCM0060_3466	COG0737	Belongs to the 5'-nucleotidase family
BCM0060_3468	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCM0060_3472	COG1695	Transcriptional regulator
BCM0060_3474	COG0174	glutamine synthetase
BCM0060_3475	COG0789	Transcriptional regulator
BCM0060_3476	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCM0060_3477	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCM0060_3478	COG2860	membrane
BCM0060_3480	COG0464	growth
BCM0060_3489	COG1388	LysM domain
BCM0060_3489	COG3584	3D domain protein
BCM0060_3490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0060_3490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCM0060_3490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCM0060_3491	COG1105	Belongs to the carbohydrate kinase PfkB family
BCM0060_3492	COG1349	DNA-binding transcription factor activity
BCM0060_3493	COG1979	alcohol dehydrogenase
BCM0060_3494	COG2322	membrane
BCM0060_3496	COG1113	amino acid transport
BCM0060_3499	COG1408	metallophosphoesterase
BCM0060_3500	COG2116	formate transmembrane transporter activity
BCM0060_3505	COG2217	Heavy metal translocating P-type atpase
BCM0060_3506	COG2608	mercury ion transmembrane transporter activity
BCM0060_3507	COG1937	Protein conserved in bacteria
BCM0060_3509	COG2819	hydrolase of the alpha beta superfamily
BCM0060_3510	COG1120	ATPase activity
BCM0060_3511	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_3512	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_3513	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_3514	COG0708	Exodeoxyribonuclease III
BCM0060_3515	COG2169	Transcriptional regulator
BCM0060_3516	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCM0060_3517	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCM0060_3519	COG2364	Membrane
BCM0060_3522	COG2267	carboxylic ester hydrolase activity
BCM0060_3523	COG0346	lactoylglutathione lyase activity
BCM0060_3524	COG3300	MHYT domain
BCM0060_3524	COG5001	Diguanylate cyclase
BCM0060_3534	COG1346	cytolysis
BCM0060_3535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCM0060_3538	COG1404	Belongs to the peptidase S8 family
BCM0060_3539	COG3773	Cell wall hydrolase
BCM0060_3541	COG1368	sulfuric ester hydrolase activity
BCM0060_3542	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCM0060_3544	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BCM0060_3548	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCM0060_3550	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCM0060_3551	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCM0060_3551	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCM0060_3553	COG2359	stage V sporulation protein S
BCM0060_3554	COG1692	metallophosphoesterase
BCM0060_3558	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCM0060_3559	COG1426	Protein conserved in bacteria
BCM0060_3562	COG0300	oxidoreductase activity
BCM0060_3563	COG0612	Peptidase, M16
BCM0060_3564	COG0612	Peptidase, M16
BCM0060_3565	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCM0060_3566	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCM0060_3567	COG3845	ABC transporter
BCM0060_3568	COG1744	ABC transporter substrate-binding protein PnrA-like
BCM0060_3569	COG2188	Transcriptional regulator
BCM0060_3570	COG1674	ftsk spoiiie
BCM0060_3572	COG0740	serine-type endopeptidase activity
BCM0060_3573	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0060_3576	COG0527	aspartate kinase activity
BCM0060_3577	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCM0060_3578	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCM0060_3579	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCM0060_3580	COG1873	PFAM PRC-barrel domain
BCM0060_3581	COG0612	Peptidase, M16
BCM0060_3582	COG0726	polysaccharide deacetylase
BCM0060_3585	COG0196	riboflavin kinase activity
BCM0060_3588	COG1550	Protein conserved in bacteria
BCM0060_3590	COG1358	cellular component organization or biogenesis
BCM0060_3591	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCM0060_3592	COG0195	Participates in both transcription termination and antitermination
BCM0060_3599	COG0750	zinc metalloprotease
BCM0060_3601	COG4589	Belongs to the CDS family
BCM0060_3604	COG0528	UMP kinase activity
BCM0060_3610	COG4974	Belongs to the 'phage' integrase family
BCM0060_3612	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCM0060_3613	COG0758	DNA mediated transformation
BCM0060_3614	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCM0060_3622	COG1837	Belongs to the UPF0109 family
BCM0060_3624	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCM0060_3626	COG0552	protein localization to endoplasmic reticulum
BCM0060_3627	COG1196	nuclear chromosome segregation
BCM0060_3629	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCM0060_3630	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3631	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCM0060_3634	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCM0060_3635	COG1461	Dihydroxyacetone kinase
BCM0060_3636	COG1302	Protein conserved in bacteria
BCM0060_3638	COG1564	THIamine pyrophosphokinase
BCM0060_3639	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCM0060_3640	COG1162	GTPase activity
BCM0060_3641	COG2815	serine threonine protein kinase
BCM0060_3641	COG0515	serine threonine protein kinase
BCM0060_3642	COG0631	protein serine/threonine phosphatase activity
BCM0060_3644	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCM0060_3644	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCM0060_3646	COG0242	peptide deformylase activity
BCM0060_3647	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCM0060_3648	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCM0060_3652	COG1561	YicC-like family, N-terminal region
BCM0060_3653	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCM0060_3655	COG0006	proline dipeptidase activity
BCM0060_3659	COG3069	C4-dicarboxylate transmembrane transporter activity
BCM0060_3671	COG0564	pseudouridine synthase activity
BCM0060_3675	COG3599	regulation of cell shape
BCM0060_3676	COG2302	S4 RNA-binding domain
BCM0060_3677	COG0762	integral membrane protein
BCM0060_3679	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCM0060_3680	COG1496	oxidoreductase activity
BCM0060_3681	COG1873	PFAM PRC-barrel domain
BCM0060_3682	COG1191	sigma factor activity
BCM0060_3683	COG1191	sigma factor activity
BCM0060_3685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCM0060_3686	COG0849	cell division
BCM0060_3687	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCM0060_3688	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCM0060_3690	COG0772	Belongs to the SEDS family
BCM0060_3693	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCM0060_3694	COG0768	penicillin binding
BCM0060_3695	COG0768	penicillin binding
BCM0060_3696	COG4839	cell division protein FtsL
BCM0060_3699	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCM0060_3702	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCM0060_3703	COG1399	metal-binding, possibly nucleic acid-binding protein
BCM0060_3705	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCM0060_3706	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCM0060_3707	COG3314	Sporulation integral membrane protein YlbJ
BCM0060_3709	COG0742	ribosomal rna small subunit methyltransferase
BCM0060_3712	COG3679	Belongs to the UPF0342 family
BCM0060_3713	COG0406	alpha-ribazole phosphatase activity
BCM0060_3716	COG2340	Cysteine-rich secretory protein family
BCM0060_3719	COG3336	cytochrome c oxidase
BCM0060_3726	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCM0060_3727	COG0772	Belongs to the SEDS family
BCM0060_3729	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCM0060_3730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCM0060_3732	COG4896	Protein conserved in bacteria
BCM0060_3735	COG1217	gtp-binding protein TYPA
BCM0060_3737	COG0483	inositol monophosphate 1-phosphatase activity
BCM0060_3741	COG1982	Orn Lys Arg decarboxylase major
BCM0060_3750	COG0022	dehydrogenase e1 component
BCM0060_3751	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0060_3753	COG0242	peptide deformylase activity
BCM0060_3754	COG0561	phosphatase activity
BCM0060_3756	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0060_3757	COG0569	domain protein
BCM0060_3761	COG0583	DNA-binding transcription factor activity
BCM0060_3762	COG0517	IMP dehydrogenase activity
BCM0060_3764	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BCM0060_3766	COG4703	Protein of unknown function (DUF1797)
BCM0060_3769	COG2200	EAL domain
BCM0060_3770	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3771	COG1408	metallophosphoesterase
BCM0060_3773	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCM0060_3780	COG2814	Major facilitator Superfamily
BCM0060_3784	COG3209	COG3209 Rhs family protein
BCM0060_3786	COG2205	protein histidine kinase activity
BCM0060_3788	COG0436	Aminotransferase
BCM0060_3789	COG1609	Transcriptional regulator
BCM0060_3790	COG3833	ABC-type maltose transport systems, permease component
BCM0060_3791	COG1175	transmembrane transport
BCM0060_3792	COG2182	Extracellular solute-binding protein
BCM0060_3794	COG0366	Alpha amylase catalytic
BCM0060_3795	COG3842	ATPase activity
BCM0060_3802	COG0183	Belongs to the thiolase family
BCM0060_3808	COG1695	Transcriptional regulator
BCM0060_3809	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_3813	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCM0060_3814	COG0436	Aminotransferase
BCM0060_3821	COG2084	Dehydrogenase
BCM0060_3822	COG2199	diguanylate cyclase activity
BCM0060_3823	COG0778	Nitroreductase
BCM0060_3828	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCM0060_3828	COG1263	PTS System
BCM0060_3828	COG2190	(PTS) system
BCM0060_3830	COG3711	transcriptional antiterminator
BCM0060_3832	COG2188	Transcriptional regulator
BCM0060_3834	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCM0060_3838	COG1547	Domain of unknown function (DUF309)
BCM0060_3839	COG0456	acetyltransferase
BCM0060_3841	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCM0060_3842	COG4086	secreted protein
BCM0060_3843	COG0561	phosphatase activity
BCM0060_3844	COG0697	spore germination
BCM0060_3847	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_3851	COG0733	neurotransmitter:sodium symporter activity
BCM0060_3855	COG1686	Belongs to the peptidase S11 family
BCM0060_3856	COG1725	Transcriptional regulator
BCM0060_3857	COG1131	(ABC) transporter
BCM0060_3860	COG1846	Transcriptional regulator
BCM0060_3863	COG0598	Magnesium transport protein CorA
BCM0060_3868	COG4974	Belongs to the 'phage' integrase family
BCM0060_3870	COG0735	belongs to the Fur family
BCM0060_3871	COG1300	Membrane
BCM0060_3875	COG0667	Aldo Keto reductase
BCM0060_3876	COG0656	L-ascorbic acid biosynthetic process
BCM0060_3877	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCM0060_3877	COG0456	acetyltransferase
BCM0060_3879	COG0737	Belongs to the 5'-nucleotidase family
BCM0060_3879	COG1525	nuclease
BCM0060_3879	COG4085	toxin activity
BCM0060_3881	COG0596	Alpha beta hydrolase
BCM0060_3882	COG2056	Na+-H+ antiporter family
BCM0060_3883	COG1609	Transcriptional regulator
BCM0060_3884	COG0456	acetyltransferase
BCM0060_3885	COG1073	alpha beta
BCM0060_3888	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCM0060_3888	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCM0060_3889	COG0307	riboflavin synthase, alpha
BCM0060_3894	COG4106	trans-aconitate 2-methyltransferase activity
BCM0060_3895	COG1073	alpha beta
BCM0060_3895	COG2226	methyltransferase
BCM0060_3898	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCM0060_3900	COG1757	Na H antiporter
BCM0060_3901	COG0737	Belongs to the 5'-nucleotidase family
BCM0060_3903	COG1522	sequence-specific DNA binding
BCM0060_3907	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCM0060_3909	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BCM0060_3912	COG0300	oxidoreductase activity
BCM0060_3913	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_3914	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0060_3915	COG1760	l-serine dehydratase
BCM0060_3916	COG1760	l-serine dehydratase
BCM0060_3920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0060_3922	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCM0060_3923	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_3925	COG1376	ErfK ybiS ycfS ynhG family protein
BCM0060_3926	COG4129	membrane
BCM0060_3927	COG1126	abc transporter atp-binding protein
BCM0060_3928	COG0765	amino acid transport
BCM0060_3929	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCM0060_3932	COG2816	NAD+ diphosphatase activity
BCM0060_3933	COG0772	Belongs to the SEDS family
BCM0060_3934	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCM0060_3935	COG0022	dehydrogenase e1 component
BCM0060_3936	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCM0060_3937	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCM0060_3940	COG0280	phosphate acetyltransferase
BCM0060_3941	COG3829	transcription factor binding
BCM0060_3941	COG3290	protein histidine kinase activity
BCM0060_3943	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0060_3944	COG3093	addiction module antidote protein HigA
BCM0060_3946	COG0745	RESPONSE REGULATOR receiver
BCM0060_3947	COG0750	zinc metalloprotease
BCM0060_3948	COG0497	DNA recombination
BCM0060_3950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCM0060_3952	COG0142	geranyltranstransferase activity
BCM0060_3957	COG1302	Protein conserved in bacteria
BCM0060_3958	COG0439	Biotin carboxylase
BCM0060_3959	COG0511	ligase activity, forming carbon-carbon bonds
BCM0060_3967	COG3854	ATPases associated with a variety of cellular activities
BCM0060_3972	COG0006	proline dipeptidase activity
BCM0060_3975	COG3872	metal-dependent enzyme
BCM0060_3977	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCM0060_3980	COG1695	Transcriptional regulator
BCM0060_3983	COG0095	Lipoate-protein ligase
BCM0060_3984	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0060_3985	COG1609	Transcriptional regulator
BCM0060_3987	COG2076	Multidrug Resistance protein
BCM0060_3988	COG2076	Multidrug Resistance protein
BCM0060_3996	COG1131	(ABC) transporter
BCM0060_3997	COG1725	Transcriptional regulator
BCM0060_4003	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0060_4014	COG4970	Tfp pilus assembly protein FimT
BCM0060_4016	COG1459	type II secretion system
BCM0060_4017	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCM0060_4027	COG0646	methionine synthase
BCM0060_4027	COG1410	methionine synthase
BCM0060_4028	COG0646	methionine synthase
BCM0060_4028	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCM0060_4029	COG0626	cystathionine gamma-synthase activity
BCM0060_4030	COG0626	cystathionine gamma-synthase activity
BCM0060_4034	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_4036	COG1940	carbohydrate kinase activity
BCM0060_4037	COG4483	Protein conserved in bacteria
BCM0060_4038	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCM0060_4039	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCM0060_4040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCM0060_4041	COG0704	Plays a role in the regulation of phosphate uptake
BCM0060_4043	COG0581	inorganic phosphate transmembrane transporter activity
BCM0060_4044	COG0573	inorganic phosphate transmembrane transporter activity
BCM0060_4045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCM0060_4046	COG0768	penicillin binding
BCM0060_4047	COG0477	Major facilitator Superfamily
BCM0060_4048	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0060_4052	COG0735	belongs to the Fur family
BCM0060_4053	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCM0060_4054	COG1121	(ABC) transporter
BCM0060_4055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_4061	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCM0060_4062	COG2384	SAM-dependent methyltransferase
BCM0060_4063	COG2010	Cytochrome c
BCM0060_4064	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCM0060_4065	COG0358	DNA primase activity
BCM0060_4067	COG0517	IMP dehydrogenase activity
BCM0060_4070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCM0060_4071	COG0295	cytidine deaminase activity
BCM0060_4072	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCM0060_4074	COG1480	7TM receptor with intracellular HD hydrolase
BCM0060_4075	COG1702	phosphate starvation-inducible protein PhoH
BCM0060_4078	COG1610	YqeY-like protein
BCM0060_4079	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCM0060_4080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCM0060_4081	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCM0060_4087	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCM0060_4088	COG1733	regulation of RNA biosynthetic process
BCM0060_4093	COG1466	dna polymerase III delta subunit
BCM0060_4095	COG2333	competence protein COMEC
BCM0060_4095	COG0658	competence protein
BCM0060_4096	COG2131	deaminase
BCM0060_4097	COG1596	polysaccharide export
BCM0060_4097	COG1555	photosystem II stabilization
BCM0060_4098	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCM0060_4099	COG2226	methyltransferase
BCM0060_4100	COG0799	negative regulation of ribosome biogenesis
BCM0060_4101	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCM0060_4103	COG1534	Rna-binding protein
BCM0060_4105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCM0060_4106	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCM0060_4113	COG0778	Nitroreductase
BCM0060_4114	COG2357	RelA SpoT domain protein
BCM0060_4116	COG1785	Belongs to the alkaline phosphatase family
BCM0060_4118	COG2267	carboxylic ester hydrolase activity
BCM0060_4125	COG1404	Belongs to the peptidase S8 family
BCM0060_4126	COG3186	Phenylalanine-4-hydroxylase
BCM0060_4128	COG2514	catechol 2,3-dioxygenase activity
BCM0060_4129	COG2259	Doxx family
BCM0060_4137	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_4139	COG1012	belongs to the aldehyde dehydrogenase family
BCM0060_4139	COG1454	alcohol dehydrogenase
BCM0060_4140	COG0626	cystathionine gamma-synthase activity
BCM0060_4141	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCM0060_4146	COG0768	penicillin binding
BCM0060_4149	COG0826	peptidase U32
BCM0060_4150	COG0826	peptidase U32
BCM0060_4151	COG4122	O-methyltransferase activity
BCM0060_4152	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCM0060_4158	COG0628	permease
BCM0060_4162	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCM0060_4165	COG1104	cysteine desulfurase activity
BCM0060_4166	COG1959	2 iron, 2 sulfur cluster binding
BCM0060_4167	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCM0060_4169	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCM0060_4174	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCM0060_4176	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCM0060_4176	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCM0060_4177	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCM0060_4178	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCM0060_4178	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCM0060_4180	COG2244	polysaccharide biosynthetic process
BCM0060_4181	COG2323	membrane
BCM0060_4183	COG1862	Preprotein translocase
BCM0060_4189	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCM0060_4191	COG0697	spore germination
BCM0060_4192	COG0640	Transcriptional regulator
BCM0060_4198	COG0157	Belongs to the NadC ModD family
BCM0060_4199	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCM0060_4200	COG1104	cysteine desulfurase activity
BCM0060_4201	COG1827	regulation of RNA biosynthetic process
BCM0060_4202	COG2258	MOSC domain
BCM0060_4203	COG0077	Prephenate dehydratase
BCM0060_4204	COG0577	efflux transmembrane transporter activity
BCM0060_4205	COG0577	efflux transmembrane transporter activity
BCM0060_4206	COG1136	(ABC) transporter
BCM0060_4207	COG5002	protein histidine kinase activity
BCM0060_4208	COG0745	RESPONSE REGULATOR receiver
BCM0060_4210	COG3290	protein histidine kinase activity
BCM0060_4212	COG2868	ribosomal protein
BCM0060_4214	COG1530	ribonuclease E activity
BCM0060_4215	COG1994	Peptidase M50
BCM0060_4216	COG0739	heme binding
BCM0060_4217	COG2894	cell division
BCM0060_4221	COG1077	Cell shape determining protein MreB Mrl
BCM0060_4225	COG0285	dihydrofolate synthase activity
BCM0060_4228	COG1388	LysM domain
BCM0060_4230	COG0113	porphobilinogen synthase activity
BCM0060_4231	COG1587	Uroporphyrinogen-III synthase
BCM0060_4233	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCM0060_4235	COG1846	Transcriptional regulator
BCM0060_4236	COG1764	response to oxidative stress
BCM0060_4239	COG0470	DNA polymerase III
BCM0060_4239	COG1067	ATP-dependent peptidase activity
BCM0060_4247	COG0622	Phosphoesterase
BCM0060_4250	COG5401	PFAM Sporulation and spore germination
BCM0060_4254	COG1309	transcriptional regulator
BCM0060_4258	COG0419	ATPase involved in DNA repair
BCM0060_4271	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCM0060_4271	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCM0060_4281	COG2197	response regulator
BCM0060_4282	COG2233	PERMEase
BCM0060_4283	COG0402	S-adenosylhomocysteine deaminase activity
BCM0060_4284	COG1983	PspC domain protein
BCM0060_4285	COG1396	sequence-specific DNA binding
BCM0060_4286	COG0697	spore germination
BCM0060_4289	COG1959	2 iron, 2 sulfur cluster binding
BCM0060_4290	COG1668	transmembrane transport
BCM0060_4291	COG4152	abc transporter atp-binding protein
BCM0060_4292	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCM0060_4293	COG1360	Flagellar Motor Protein
BCM0060_4294	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCM0060_4295	COG1876	peptidase activity
BCM0060_4296	COG0824	Thioesterase
BCM0060_4297	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCM0060_4298	COG1053	succinate dehydrogenase
BCM0060_4299	COG2009	succinate dehydrogenase
BCM0060_4300	COG1719	4-vinyl reductase, 4VR
BCM0060_4302	COG3118	belongs to the thioredoxin family
BCM0060_4303	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCM0060_4304	COG2086	electron transfer activity
BCM0060_4305	COG1024	Enoyl-CoA hydratase
BCM0060_4306	COG1309	transcriptional regulator
BCM0060_4307	COG0318	PFAM AMP-dependent synthetase and ligase
BCM0060_4311	COG2318	DinB family
BCM0060_4316	COG1131	(ABC) transporter
BCM0060_4317	COG2205	protein histidine kinase activity
BCM0060_4318	COG0745	RESPONSE REGULATOR receiver
BCM0060_4320	COG4895	conserved protein (DUF2196)
BCM0060_4321	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCM0060_4324	COG4509	Sortase family
BCM0060_4325	COG1120	ATPase activity
BCM0060_4328	COG5386	Cell surface protein
BCM0060_4329	COG5386	Cell surface protein
BCM0060_4331	COG1114	Component of the transport system for branched-chain amino acids
BCM0060_4332	COG1187	pseudouridine synthase activity
BCM0060_4334	COG1796	DNA polymerase
BCM0060_4334	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCM0060_4335	COG1286	toxin biosynthetic process
BCM0060_4344	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCM0060_4346	COG1418	mRNA catabolic process
BCM0060_4353	COG2814	Major facilitator Superfamily
BCM0060_4354	COG1566	PFAM secretion protein HlyD family protein
BCM0060_4355	COG1309	transcriptional regulator
BCM0060_4356	COG1363	Peptidase, m42
BCM0060_4361	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCM0060_4363	COG1484	DNA-dependent DNA replication
BCM0060_4364	COG3611	Membrane attachment protein
BCM0060_4366	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCM0060_4367	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCM0060_4368	COG0237	dephospho-CoA kinase activity
BCM0060_4369	COG1971	Probably functions as a manganese efflux pump
BCM0060_4371	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0060_4371	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCM0060_4372	COG5002	protein histidine kinase activity
BCM0060_4373	COG0745	RESPONSE REGULATOR receiver
BCM0060_4378	COG0538	isocitrate dehydrogenase activity
BCM0060_4379	COG0372	Belongs to the citrate synthase family
BCM0060_4381	COG0628	permease
BCM0060_4382	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCM0060_4387	COG1725	Transcriptional regulator
BCM0060_4388	COG0281	malic enzyme
BCM0060_4389	COG0587	DNA-directed DNA polymerase activity
BCM0060_4392	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCM0060_4395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0060_4397	COG4109	DRTGG domain
BCM0060_4400	COG0006	proline dipeptidase activity
BCM0060_4408	COG0662	Cupin 2, conserved barrel domain protein
BCM0060_4410	COG1476	TRANSCRIPTIONal
BCM0060_4413	COG1028	Short-chain dehydrogenase reductase Sdr
BCM0060_4414	COG0589	response to stress
BCM0060_4422	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_4425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCM0060_4426	COG0827	DNA restriction-modification system
BCM0060_4427	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCM0060_4428	COG3874	Sporulation protein YtfJ
BCM0060_4431	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BCM0060_4433	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0060_4437	COG1104	cysteine desulfurase activity
BCM0060_4439	COG0583	DNA-binding transcription factor activity
BCM0060_4440	COG0697	spore germination
BCM0060_4441	COG1309	transcriptional regulator
BCM0060_4442	COG1956	GAF domain-containing protein
BCM0060_4443	COG0626	cystathionine gamma-synthase activity
BCM0060_4453	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCM0060_4454	COG0454	-acetyltransferase
BCM0060_4455	COG0517	IMP dehydrogenase activity
BCM0060_4456	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCM0060_4459	COG0745	RESPONSE REGULATOR receiver
BCM0060_4460	COG5002	protein histidine kinase activity
BCM0060_4461	COG0666	response to abiotic stimulus
BCM0060_4468	COG1609	Transcriptional regulator
BCM0060_4469	COG4851	CamS sex pheromone cAM373 precursor
BCM0060_4470	COG3118	belongs to the thioredoxin family
BCM0060_4472	COG2309	aminopeptidase activity
BCM0060_4475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_4479	COG1674	ftsk spoiiie
BCM0060_4481	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCM0060_4483	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0060_4484	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BCM0060_4485	COG1363	Peptidase, m42
BCM0060_4487	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_4490	COG0510	thiamine kinase activity
BCM0060_4491	COG1523	belongs to the glycosyl hydrolase 13 family
BCM0060_4493	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCM0060_4494	COG1349	DNA-binding transcription factor activity
BCM0060_4495	COG1187	pseudouridine synthase activity
BCM0060_4496	COG2244	polysaccharide biosynthetic process
BCM0060_4497	COG2081	HI0933 family
BCM0060_4498	COG2814	Major facilitator Superfamily
BCM0060_4500	COG3832	glyoxalase III activity
BCM0060_4504	COG1329	Transcriptional regulator
BCM0060_4509	COG0314	molybdopterin synthase activity
BCM0060_4510	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCM0060_4511	COG0303	'Molybdopterin
BCM0060_4513	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCM0060_4514	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCM0060_4518	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCM0060_4520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCM0060_4530	COG2814	Major facilitator Superfamily
BCM0060_4531	COG0475	glutathione-regulated potassium exporter activity
BCM0060_4532	COG0490	domain, Protein
BCM0060_4533	COG0582	viral genome integration into host DNA
BCM0060_4535	COG1136	(ABC) transporter
BCM0060_4540	COG1242	4 iron, 4 sulfur cluster binding
BCM0060_4541	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCM0060_4544	COG1794	racemase activity, acting on amino acids and derivatives
BCM0060_4546	COG5504	Zn-dependent protease
BCM0060_4551	COG2267	carboxylic ester hydrolase activity
BCM0060_4552	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCM0060_4553	COG0671	phosphoesterase, PA-phosphatase related
BCM0060_4554	COG0438	transferase activity, transferring glycosyl groups
BCM0060_4556	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCM0060_4569	COG0546	phosphoglycolate phosphatase activity
BCM0060_4570	COG1349	DNA-binding transcription factor activity
BCM0060_4572	COG5002	protein histidine kinase activity
BCM0060_4573	COG4191	Histidine kinase
BCM0060_4574	COG2267	carboxylic ester hydrolase activity
BCM0060_4575	COG1368	sulfuric ester hydrolase activity
BCM0060_4578	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCM0060_4579	COG1116	anion transmembrane transporter activity
BCM0060_4580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCM0060_4583	COG0546	phosphoglycolate phosphatase activity
BCM0060_4585	COG0494	nUDIX hydrolase
BCM0060_4591	COG0288	reversible hydration of carbon dioxide
BCM0060_4592	COG1271	oxidase subunit
BCM0060_4593	COG1294	oxidase, subunit
BCM0060_4597	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_4602	COG1842	Phage shock protein A
BCM0060_4609	COG3859	Proton-coupled thiamine transporter YuaJ
BCM0060_4610	COG5002	protein histidine kinase activity
BCM0060_4611	COG0745	RESPONSE REGULATOR receiver
BCM0060_4616	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCM0060_4617	COG1597	lipid kinase activity
BCM0060_4623	COG0586	Pfam SNARE associated Golgi protein
BCM0060_4625	COG0577	efflux transmembrane transporter activity
BCM0060_4626	COG1136	(ABC) transporter
BCM0060_4627	COG2207	Transcriptional regulator
BCM0060_4627	COG3708	Transcriptional regulator
BCM0060_4629	COG1595	DNA-templated transcription, initiation
BCM0060_4630	COG0745	RESPONSE REGULATOR receiver
BCM0060_4631	COG2205	protein histidine kinase activity
BCM0060_4632	COG0577	efflux transmembrane transporter activity
BCM0060_4633	COG0577	efflux transmembrane transporter activity
BCM0060_4634	COG1136	(ABC) transporter
BCM0060_4635	COG0577	efflux transmembrane transporter activity
BCM0060_4638	COG2188	Transcriptional regulator
BCM0060_4642	COG3964	amidohydrolase
BCM0060_4646	COG4948	Mandelate Racemase Muconate Lactonizing
BCM0060_4648	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCM0060_4649	COG0596	Alpha beta hydrolase
BCM0060_4651	COG1169	isochorismate synthase
BCM0060_4652	COG1575	Belongs to the MenA family. Type 1 subfamily
BCM0060_4653	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCM0060_4657	COG0058	SHG alpha-glucan phosphorylase activity
BCM0060_4659	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCM0060_4663	COG1404	Belongs to the peptidase S8 family
BCM0060_4665	COG1285	pathogenesis
BCM0060_4666	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCM0060_4669	COG2155	Conserved Protein
BCM0060_4670	COG1098	S1 RNA binding domain
BCM0060_4671	COG0436	Aminotransferase
BCM0060_4672	COG1522	sequence-specific DNA binding
BCM0060_4673	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCM0060_4674	COG2267	carboxylic ester hydrolase activity
BCM0060_4676	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCM0060_4680	COG5018	Exonuclease
BCM0060_4681	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0060_4685	COG2050	protein possibly involved in aromatic compounds catabolism
BCM0060_4687	COG1268	BioY protein
BCM0060_4688	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCM0060_4689	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCM0060_4692	COG3584	3D domain protein
BCM0060_4695	COG1252	NADH dehydrogenase
BCM0060_4701	COG1683	Conserved Protein
BCM0060_4703	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCM0060_4707	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCM0060_4731	COG5492	domain, Protein
BCM0060_4754	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCM0060_4757	COG0316	Belongs to the HesB IscA family
BCM0060_4760	COG1252	NADH dehydrogenase
BCM0060_4761	COG2274	protein secretion by the type I secretion system
BCM0060_4762	COG0390	transport system, permease component
BCM0060_4763	COG2824	Alkylphosphonate utilization operon protein PhnA
BCM0060_4767	COG4837	Protein of unknown function (DUF1462)
BCM0060_4768	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCM0060_4770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCM0060_4771	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCM0060_4774	COG1136	(ABC) transporter
BCM0060_4774	COG0577	efflux transmembrane transporter activity
BCM0060_4775	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCM0060_4777	COG0647	UMP catabolic process
BCM0060_4779	COG2445	Protein of unknown function DUF86
BCM0060_4780	COG1494	fructose-1,6-bisphosphatase
BCM0060_4783	COG4470	Protein conserved in bacteria
BCM0060_4785	COG0789	Transcriptional regulator
BCM0060_4786	COG4377	Putative membrane peptidase family (DUF2324)
BCM0060_4791	COG0739	heme binding
BCM0060_4793	COG3377	Domain of unknown function (DUF1805)
BCM0060_4794	COG0737	Belongs to the 5'-nucleotidase family
BCM0060_4795	COG1695	Transcriptional regulator
BCM0060_4797	COG0719	Fe-S assembly protein
BCM0060_4798	COG0822	iron-sulfur transferase activity
BCM0060_4799	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCM0060_4800	COG0719	Fe-S assembly protein
BCM0060_4801	COG0396	ATPase activity
BCM0060_4802	COG1464	Belongs to the NlpA lipoprotein family
BCM0060_4803	COG1464	Belongs to the NlpA lipoprotein family
BCM0060_4804	COG2011	ABC-type metal ion transport system permease component
BCM0060_4805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCM0060_4807	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCM0060_4808	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCM0060_4810	COG1393	Belongs to the ArsC family
BCM0060_4820	COG0039	L-malate dehydrogenase activity
BCM0060_4825	COG1309	transcriptional regulator
BCM0060_4826	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCM0060_4830	COG4555	ABC transporter
BCM0060_4837	COG1960	acyl-CoA dehydrogenase activity
BCM0060_4838	COG0183	Belongs to the thiolase family
BCM0060_4839	COG1024	Enoyl-CoA hydratase
BCM0060_4839	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCM0060_4841	COG1686	Belongs to the peptidase S11 family
BCM0060_4844	COG0011	TIGRFAM Protein of
BCM0060_4845	COG0840	transmembrane signaling receptor activity
BCM0060_4849	COG2814	Major facilitator Superfamily
BCM0060_4850	COG0531	amino acid
BCM0060_4853	COG0706	membrane insertase activity
BCM0060_4855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCM0060_4862	COG0586	Pfam SNARE associated Golgi protein
BCM0060_4864	COG1376	ErfK ybiS ycfS ynhG family protein
BCM0060_4865	COG0745	RESPONSE REGULATOR receiver
BCM0060_4866	COG5002	protein histidine kinase activity
BCM0060_4871	COG0840	transmembrane signaling receptor activity
BCM0060_4872	COG2151	metal-sulfur cluster biosynthetic enzyme
BCM0060_4873	COG3227	Zinc metalloprotease (Elastase)
BCM0060_4874	COG1741	Belongs to the pirin family
BCM0060_4877	COG0475	glutathione-regulated potassium exporter activity
BCM0060_4878	COG0490	domain, Protein
BCM0060_4880	COG1115	amino acid carrier protein
BCM0060_4881	COG0783	Belongs to the Dps family
BCM0060_4884	COG1611	Belongs to the LOG family
BCM0060_4888	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_4889	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_4890	COG1115	amino acid carrier protein
BCM0060_4891	COG1115	amino acid carrier protein
BCM0060_4892	COG2910	NAD(P)H-binding
BCM0060_4895	COG0656	L-ascorbic acid biosynthetic process
BCM0060_4896	COG2814	Major facilitator Superfamily
BCM0060_4897	COG1733	regulation of RNA biosynthetic process
BCM0060_4899	COG1252	NADH dehydrogenase
BCM0060_4900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCM0060_4905	COG0840	transmembrane signaling receptor activity
BCM0060_4905	COG3290	protein histidine kinase activity
BCM0060_4907	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCM0060_4912	COG0488	(ABC) transporter
BCM0060_4913	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCM0060_4923	COG0557	exoribonuclease II activity
BCM0060_4924	COG1647	Serine aminopeptidase, S33
BCM0060_4925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCM0060_4926	COG1346	cytolysis
BCM0060_4933	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCM0060_4936	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCM0060_4943	COG4974	Belongs to the 'phage' integrase family
BCM0060_4947	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_4950	COG2323	membrane
BCM0060_4952	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCM0060_4954	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCM0060_4956	COG1051	belongs to the nudix hydrolase family
BCM0060_4958	COG0492	ferredoxin-NADP+ reductase activity
BCM0060_4959	COG0457	Tetratricopeptide repeat
BCM0060_4960	COG0110	maltose O-acetyltransferase activity
BCM0060_4964	COG1950	PFAM Membrane protein of
BCM0060_4966	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCM0060_4967	COG0556	nucleotide-excision repair
BCM0060_4970	COG0789	Transcriptional regulator
BCM0060_4975	COG2855	membrane
BCM0060_4976	COG0583	DNA-binding transcription factor activity
BCM0060_4978	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCM0060_4979	COG0488	(ABC) transporter
BCM0060_4981	COG1132	(ABC) transporter
BCM0060_4983	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0060_4984	COG0793	Belongs to the peptidase S41A family
BCM0060_4984	COG3409	Peptidoglycan-binding domain 1 protein
BCM0060_4985	COG2177	Part of the ABC transporter FtsEX involved in
BCM0060_4986	COG2884	Cell division ATP-binding protein ftsE
BCM0060_4988	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCM0060_4990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCM0060_4991	COG1278	Cold shock
BCM0060_4992	COG1040	competence protein
BCM0060_4993	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCM0060_4994	COG1388	LysM domain
BCM0060_4994	COG0791	NLP P60 protein
BCM0060_4995	COG1733	regulation of RNA biosynthetic process
BCM0060_4996	COG1307	EDD domain protein, DegV family
BCM0060_4997	COG1739	Uncharacterized protein family UPF0029
BCM0060_4998	COG1316	TRANSCRIPTIONal
BCM0060_4999	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCM0060_5000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCM0060_5001	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCM0060_5003	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCM0060_5003	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCM0060_5007	COG1486	melibiose metabolic process
BCM0060_5008	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0060_5009	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0060_5011	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCM0060_5015	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCM0060_5017	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCM0060_5018	COG1301	dicarboxylic acid transport
BCM0060_5020	COG0346	lactoylglutathione lyase activity
BCM0060_5024	COG1511	domain protein
BCM0060_5025	COG0583	DNA-binding transcription factor activity
BCM0060_5026	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCM0060_5028	COG1271	oxidase subunit
BCM0060_5029	COG1294	oxidase, subunit
BCM0060_5030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCM0060_5032	COG1620	l-lactate permease
BCM0060_5035	COG2389	metal-binding protein
BCM0060_5038	COG1368	sulfuric ester hydrolase activity
BCM0060_5040	COG0791	NLP P60 protein
BCM0060_5040	COG1388	LysM domain
BCM0060_5041	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCM0060_5043	COG1215	transferase activity, transferring glycosyl groups
BCM0060_5045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0060_5046	COG3584	3D domain protein
BCM0060_5046	COG1388	LysM domain
BCM0060_5051	COG4715	Zinc finger, swim domain protein
BCM0060_5052	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCM0060_5062	COG0577	efflux transmembrane transporter activity
BCM0060_5063	COG1136	(ABC) transporter
BCM0060_5071	COG0745	RESPONSE REGULATOR receiver
BCM0060_5072	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCM0060_5076	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCM0060_5077	COG1134	teichoic acid transport
BCM0060_5078	COG1682	transport, permease protein
BCM0060_5079	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCM0060_5089	COG1609	Transcriptional regulator
BCM0060_5092	COG0739	heme binding
BCM0060_5095	COG3279	Response regulator of the LytR AlgR family
BCM0060_5096	COG2385	sporulation resulting in formation of a cellular spore
BCM0060_5099	COG4836	Membrane
BCM0060_5100	COG1007	ATP synthesis coupled electron transport
BCM0060_5101	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCM0060_5102	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCM0060_5104	COG0839	Belongs to the complex I subunit 6 family
BCM0060_5108	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCM0060_5111	COG5001	Diguanylate cyclase
BCM0060_5111	COG3300	MHYT domain
BCM0060_5121	COG0356	it plays a direct role in the translocation of protons across the membrane
BCM0060_5127	COG0698	ribose 5-phosphate isomerase
BCM0060_5129	COG2190	(PTS) system
BCM0060_5130	COG2259	Doxx family
BCM0060_5131	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCM0060_5135	COG0009	L-threonylcarbamoyladenylate synthase
BCM0060_5138	COG2890	protein-(glutamine-N5) methyltransferase activity
BCM0060_5142	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCM0060_5143	COG1494	fructose-1,6-bisphosphatase
BCM0060_5147	COG4821	SIS domain
BCM0060_5151	COG1960	acyl-CoA dehydrogenase activity
BCM0060_5152	COG1960	acyl-CoA dehydrogenase activity
BCM0060_5153	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCM0060_5154	COG0183	Belongs to the thiolase family
BCM0060_5155	COG0247	lactate metabolic process
BCM0060_5155	COG2181	nitrate reductase activity
BCM0060_5156	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCM0060_5158	COG5001	Diguanylate cyclase
BCM0060_5158	COG3300	MHYT domain
BCM0060_5162	COG2197	response regulator
BCM0060_5163	COG4585	Histidine kinase
BCM0060_5164	COG0842	Transport permease protein
BCM0060_5165	COG1131	(ABC) transporter
BCM0060_5166	COG0024	Methionine aminopeptidase
BCM0060_5168	COG2234	aminopeptidase activity
BCM0060_5172	COG1595	DNA-templated transcription, initiation
BCM0060_5174	COG4506	Protein conserved in bacteria
BCM0060_5175	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCM0060_5178	COG0010	Belongs to the arginase family
BCM0060_5180	COG2814	Major facilitator Superfamily
BCM0060_5181	COG0789	Transcriptional regulator
BCM0060_5182	COG0584	glycerophosphoryl diester phosphodiesterase
BCM0060_5183	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCM0060_5185	COG1994	Peptidase M50
BCM0060_5187	COG1078	dGTPase activity
BCM0060_5188	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCM0060_5189	COG1120	ATPase activity
BCM0060_5190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_5191	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCM0060_5195	COG0095	Lipoate-protein ligase
BCM0060_5196	COG0280	phosphate acetyltransferase
BCM0060_5199	COG3773	Cell wall hydrolase
BCM0060_5201	COG2363	Small membrane protein
BCM0060_5203	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCM0060_5204	COG2233	PERMEase
BCM0060_5205	COG0561	phosphatase activity
BCM0060_5206	COG2814	Major facilitator Superfamily
BCM0060_5208	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCM0060_5209	COG1131	(ABC) transporter
BCM0060_5210	COG2755	lipolytic protein G-D-S-L family
BCM0060_5211	COG1609	Transcriptional regulator
BCM0060_5213	COG0460	homoserine dehydrogenase
BCM0060_5215	COG2873	o-acetylhomoserine
BCM0060_5216	COG1011	Hydrolase
BCM0060_5217	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCM0060_5220	COG2197	response regulator
BCM0060_5221	COG4585	Histidine kinase
BCM0060_5221	COG2203	Gaf domain
BCM0060_5222	COG0351	phosphomethylpyrimidine kinase
BCM0060_5223	COG3706	GGDEF domain
BCM0060_5224	COG2879	small protein
BCM0060_5225	COG1966	Carbon starvation protein
BCM0060_5226	COG3279	Response regulator of the LytR AlgR family
BCM0060_5227	COG0477	Major facilitator Superfamily
BCM0060_5232	COG0840	transmembrane signaling receptor activity
BCM0060_5242	COG1607	acyl-coa hydrolase
BCM0060_5246	COG0488	(ABC) transporter
BCM0060_5250	COG0463	Glycosyl transferase, family 2
BCM0060_5251	COG1309	transcriptional regulator
BCM0060_5252	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCM0060_5253	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0060_5253	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCM0060_5254	COG0628	permease
BCM0060_5257	COG3279	Response regulator of the LytR AlgR family
BCM0060_5258	COG3275	phosphorelay sensor kinase activity
BCM0060_5259	COG2814	Major facilitator Superfamily
BCM0060_5260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCM0060_5261	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BCM0060_5262	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCM0060_5266	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCM0060_5267	COG1272	protein, Hemolysin III
BCM0060_5272	COG1164	Oligoendopeptidase f
BCM0060_5276	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCM0060_5277	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCM0060_5278	COG4853	Protein conserved in bacteria
BCM0060_5279	COG4863	YycH protein
BCM0060_5280	COG5002	protein histidine kinase activity
BCM0060_5281	COG0745	RESPONSE REGULATOR receiver
BCM0060_5283	COG0305	Participates in initiation and elongation during chromosome replication
BCM0060_5285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCM0060_5286	COG4241	membrane
BCM0060_5288	COG0629	single-stranded DNA binding
BCM0060_5290	COG0012	GTP binding
BCM0060_5291	COG4481	Protein conserved in bacteria
BCM0060_5292	COG0668	transmembrane transport
BCM0060_5294	COG1475	DNA binding
BCM0060_5295	COG1192	Involved in chromosome partitioning
BCM0060_5300	COG1847	R3H domain protein
BCM0060_5301	COG0706	membrane insertase activity
BCM0060_5303	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCM0060_p1002	COG3344	reverse transcriptase
BCM0060_p1030	COG3344	reverse transcriptase
BCM0060_p1039	COG4372	Transposase
BCM0060_p1040	COG3546	catalase activity
BCM0060_p1043	COG0305	Participates in initiation and elongation during chromosome replication
BCM0060_p1064	COG3344	reverse transcriptase
BCM0060_p1088	COG0457	Tetratricopeptide repeat
BCM0060_p1091	COG4974	Belongs to the 'phage' integrase family
BCM0060_p1097	COG5002	protein histidine kinase activity
BCM0060_p1099	COG0745	RESPONSE REGULATOR receiver
BCM0060_p1100	COG4990	cell redox homeostasis
BCM0060_p1101	COG1335	isochorismatase
BCM0060_p1112	COG2918	glutathione biosynthetic process
BCM0060_p1112	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCM0060_p1114	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BCM0060_p1116	COG1733	regulation of RNA biosynthetic process
BCM0060_p1120	COG0697	spore germination
BCM0060_p1125	COG2323	membrane
BCM0060_p1128	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCM0060_p1138	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCM0060_p1141	COG3708	Transcriptional regulator
BCM0060_p1141	COG2207	Transcriptional regulator
BCM0060_p1151	COG0789	Transcriptional regulator
BCM0060_p1167	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCM0060_p1170	COG4166	transmembrane transport
BCM0060_p1176	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCM0060_p1177	COG4977	sequence-specific DNA binding
BCM0060_p1180	COG4974	Belongs to the 'phage' integrase family
BCM0060_p1189	COG2002	toxin-antitoxin pair type II binding
BCM0060_p1204	COG2311	Membrane
BCM0060_p1220	COG3344	reverse transcriptase
BCM0060_p1238	COG0798	PFAM Bile acid sodium symporter
BCM0060_p1239	COG0640	Transcriptional regulator
BCM0060_p1242	COG2824	Alkylphosphonate utilization operon protein PhnA
BCM0060_p1245	COG0659	secondary active sulfate transmembrane transporter activity
BCM0060_p1248	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCM0060_p1249	COG0659	secondary active sulfate transmembrane transporter activity
BCM0060_p1250	COG0589	response to stress
BCM0060_p1251	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCM0060_p1253	COG2072	flavoprotein involved in K transport
BCM0060_p1256	COG0640	Transcriptional regulator
BCM0060_p1277	COG2801	Transposase and inactivated derivatives
BCM0060_p1278	COG2963	transposase activity
BCM0060_p2004	COG0546	phosphoglycolate phosphatase activity
BCM0060_p2025	COG2801	Transposase and inactivated derivatives
BCM0060_p2032	COG4824	toxin secretion phage lysis holin
BCM0060_p2042	COG1780	Probably involved in ribonucleotide reductase function
BCM0060_p2052	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCM0060_p2055	COG4372	Transposase
BCM0060_p2060	COG2801	Transposase and inactivated derivatives
BCM0060_p2068	COG0681	Belongs to the peptidase S26 family
BCM0060_p2073	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCM0060_p2083	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCM0060_p2101	COG3344	reverse transcriptase
BCM0060_p2105	COG0741	lytic transglycosylase activity
BCM0060_p2105	COG0791	NLP P60 protein
BCM0060_p2109	COG0582	viral genome integration into host DNA
BCM0060_p2122	COG2003	Belongs to the UPF0758 family
BCM0060_p2124	COG3012	SEC-C Motif Domain Protein
BCM0060_p2124	COG1405	negative regulation of cell septum assembly
BCM0060_p2147	COG4974	Belongs to the 'phage' integrase family
BCM0060_p2151	COG1674	ftsk spoiiie
BCM0060_p2162	COG0582	viral genome integration into host DNA
BCM0060_p2170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCM0060_p2170	COG0758	DNA mediated transformation
BCM0060_p2178	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCM0060_p2195	COG0457	Tetratricopeptide repeat
BCM0060_p2215	COG4974	Belongs to the 'phage' integrase family
BCM0060_p2216	COG2801	Transposase and inactivated derivatives
BCM0060_p2226	COG3708	Transcriptional regulator
BCM0060_p2226	COG2207	Transcriptional regulator
BCM0060_p56	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCM0060_t0096	COG0544	peptidyl-prolyl cis-trans isomerase activity