locus-tag class description BCN_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCN_0003 ENOG410848D S4 domain protein YaaA BCN_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCN_0009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCN_0015 ENOG4105ZMH deoxynucleoside kinase BCN_0017 ENOG4105GTG Isochorismatase BCN_0019 ENOG4108Z6B deaminase BCN_0020 ENOG4105C6E dna polymerase iii BCN_0024 ENOG41067KS pro-sigma K processing BCN_0026 ENOG4105CXN decarboxylase BCN_0028 ENOG4105FA2 dna polymerase iii BCN_0029 ENOG4105MA4 psp1 domain protein BCN_0031 ENOG41060K3 Methyltransferase BCN_0033 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCN_0034 ENOG4105KRN Transcriptional regulator, abrb family BCN_0036 ENOG4105F8V Hydrolase, tatD family BCN_0037 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCN_0039 ENOG4105XFA sporulation peptidase YabG BCN_0040 ENOG4105W42 Veg protein BCN_0043 ENOG4105DFT pur operon repressor BCN_0044 ENOG4105KME endoribonuclease L-psp BCN_0047 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCN_0050 ENOG4108JA2 transcriptioN-repair coupling factor BCN_0051 ENOG4108M14 stage v sporulation protein t BCN_0053 ENOG4108IY2 MazG family BCN_0054 ENOG41082I2 s4 domain protein BCN_0055 ENOG4105VYY sporulation protein yabp BCN_0058 ENOG41060GV RNA binding s1 domain protein BCN_0061 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCN_0062 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCN_0065 ENOG4105C6T cysteine synthase BCN_0066 ENOG4105CRQ synthase (Component I) BCN_0067 ENOG4105DDQ anthranilate synthase BCN_0068 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCN_0069 ENOG4105EEI dihydropteroate synthase BCN_0070 ENOG4105KRF dihydroneopterin aldolase BCN_0071 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCN_0073 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCN_0079 ENOG4108Z0C Uvrb UvrC protein BCN_0082 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCN_0084 ENOG4105CTP PilT protein domain protein BCN_0088 ENOG4105D7W serine acetyltransferase BCN_0091 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCN_0092 ENOG4105M0M Tetracycline resistance protein BCN_0093 ENOG4105QIV RNA polymerase BCN_0096 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCN_0101 ENOG4107Y49 methyltransferase BCN_0104 ENOG4105XPM ribosomal protein BCN_0125 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCN_0130 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCN_0132 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCN_0134 ENOG41067V7 50S ribosomal protein L36 BCN_0140 ENOG4108JJB ABC transporter BCN_0141 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCN_0147 ENOG4105D1F ATP-binding protein BCN_0150 ENOG4108NMV polysaccharide deacetylase BCN_0154 ENOG4105C8B TIGR00159 family BCN_0155 ENOG4107U5W ybbr family BCN_0159 ENOG4108VQT Alpha beta hydrolase fold protein BCN_0161 ENOG4105CMG Carbohydrate kinase BCN_0163 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BCN_0171 ENOG4108PSK reductase BCN_0172 ENOG4108UMI ABC transporter, permease BCN_0174 ENOG4105D01 (LipO)protein BCN_0175 ENOG4105EE1 crotonyl-CoA reductase BCN_0177 ENOG4105IQ5 FAD linked oxidase domain protein BCN_0180 ENOG4105C2C drug resistance transporter, Bcr CflA BCN_0183 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCN_0184 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCN_0185 ENOG4105C3U ABC transporter BCN_0186 ENOG4108JQ7 (ABC) transporter BCN_0190 ENOG4108J59 Extracellular solute-binding protein, family 5 BCN_0191 ENOG4108J59 Extracellular solute-binding protein, family 5 BCN_0195 ENOG4107XDY Nicotinamide Mononucleotide Transporter BCN_0197 ENOG4105E0C molybdate abc transporter BCN_0199 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCN_0200 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCN_0208 ENOG4105F6E Acyl-transferase BCN_0213 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCN_0216 ENOG4108RE7 deoxyribonuclease BCN_0217 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCN_0221 ENOG4105C5H ABC transporter BCN_0223 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCN_0224 ENOG4105DEF Extracellular solute-binding protein, family 5 BCN_0226 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCN_0227 ENOG4105C3U ABC transporter BCN_0228 ENOG4108JQ7 (ABC) transporter BCN_0229 ENOG410667J hydrolase BCN_0231 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCN_0232 ENOG4105ERH Fumarylacetoacetate hydrolase BCN_0235 ENOG4105CUB amino acid BCN_0236 ENOG4108SC4 )-transporter BCN_0237 ENOG4105CPF Cell wall formation (By similarity) BCN_0238 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCN_0243 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCN_0244 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCN_0246 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCN_0251 ENOG4105K8N protein family UPF0079, ATPase BCN_0252 ENOG41072GX Peptidase M22 Glycoprotease BCN_0253 ENOG410801F ribosomal-protein-alanine acetyltransferase BCN_0256 ENOG4105C5H ABC transporter BCN_0259 ENOG4108TYN CAAX amino terminal protease family protein BCN_0263 ENOG4105C7N Xanthine uracil vitamin C permease BCN_0265 ENOG4105BZU Histidine kinase BCN_0268 ENOG4107ZXU DSBA oxidoreductase BCN_0271 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCN_0275 ENOG4108SHN Glycosyl transferase, family 2 BCN_0276 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCN_0280 ENOG4105SX7 Transporter BCN_0282 ENOG4105DQ6 Transposase BCN_0284 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCN_0285 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCN_0286 ENOG4105C83 adenylosuccinate lyase BCN_0288 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCN_0293 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCN_0296 ENOG4105C12 Phosphoribosylglycinamide synthetase BCN_0301 ENOG4105C4R Atp-dependent dna helicase BCN_0307 ENOG4108W2Y isochorismatase BCN_0309 ENOG4108UMI ABC transporter, permease BCN_0310 ENOG4105D01 (LipO)protein BCN_0314 ENOG410834F Transcriptional regulator BCN_0315 ENOG4107I77 yiaA/B two helix domain BCN_0319 ENOG4105CBD Diacylglycerol kinase BCN_0320 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCN_0321 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BCN_0322 ENOG4108JPW Aminotransferase BCN_0324 ENOG4105C26 Dehydrogenase BCN_0325 ENOG4105KPY Small multidrug resistance protein BCN_0328 ENOG4105D9N nucleoside BCN_0329 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCN_0331 ENOG4105BZU Histidine kinase BCN_0332 ENOG4105C7K acetolactate synthase BCN_0334 ENOG4108W15 Protein of unknown function (DUF1456) BCN_0339 ENOG4105DDC Oxidoreductase domain protein BCN_0340 ENOG4105CQB FAD linked oxidase domain protein BCN_0341 ENOG4105CWC Acetylornithine deacetylase BCN_0344 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BCN_0345 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCN_0347 ENOG4107Y80 Major Facilitator superfamily BCN_0350 ENOG4108W15 Protein of unknown function (DUF1456) BCN_0353 ENOG4105DTQ mandelate racemase muconate lactonizing BCN_0355 ENOG4105DFD Na H antiporter BCN_0359 ENOG4105D3R alkyl hydroperoxide reductase BCN_0360 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BCN_0362 ENOG4107W7X Aldolase BCN_0365 ENOG4105EHG Permease protein BCN_0366 ENOG4105DQ5 transport system permease protein BCN_0367 ENOG4108V5C ABC transporter BCN_0372 ENOG4106UIA BCN_0373 ENOG4106UIA BCN_0380 ENOG410756H nucleotidyltransferase BCN_0381 ENOG4105D2S major facilitator superfamily BCN_0386 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCN_0387 ENOG4105E5Q amino acid AbC transporter BCN_0388 ENOG4105EAB amino acid AbC transporter BCN_0390 ENOG4105C8Q Methyl-accepting chemotaxis BCN_0392 ENOG4105CI1 PTS System BCN_0398 ENOG4107RBB ABC transporter, permease BCN_0399 ENOG4105C19 ABC transporter BCN_0404 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BCN_0411 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCN_0415 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCN_0419 ENOG4105C5H ABC transporter BCN_0425 ENOG41062JF Transcriptional regulator BCN_0429 ENOG4105DEU major facilitator superfamily BCN_0435 ENOG4108N0M stress protein BCN_0436 ENOG4106FN3 tellurium resistance protein BCN_0437 ENOG4106FN3 tellurium resistance protein BCN_0438 ENOG4107TS3 membrane protein, TerC BCN_0439 ENOG4108TTB tellurium resistance protein BCN_0443 ENOG4105KJF protein tyrosine phosphatase BCN_0445 ENOG4107U9T Pfam:Ribonuclease_BN BCN_0446 ENOG4105C59 p-type ATPase BCN_0447 ENOG4108IPJ Membrane BCN_0450 ENOG4105C3F Signal peptidase i BCN_0452 ENOG4107ZTW SNARE associated Golgi BCN_0455 ENOG410606W general stress protein BCN_0456 ENOG4105UPD Calcium Proton BCN_0466 ENOG4108JUB Transcriptional regulator BCN_0468 ENOG4108IQI permease BCN_0474 ENOG4105DQ6 Transposase BCN_0476 ENOG4105CSV Glutaminase BCN_0479 ENOG4108A04 Beta-lactamase BCN_0482 ENOG4105CKK Glycosyl transferase, family 2 BCN_0483 ENOG4107QQG Dehydrogenase BCN_0484 ENOG4105C3I Nad-dependent epimerase dehydratase BCN_0487 ENOG4105F1A Pyruvate formate-lyase BCN_0491 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BCN_0492 ENOG4105ECP epimerase BCN_0498 ENOG41067AE Membrane-bound metal-dependent hydrolase BCN_0499 ENOG4105CEN a g-specific adenine glycosylase BCN_0500 ENOG4106BXE BCN_0504 ENOG4105BZ1 (ABC) transporter BCN_0505 ENOG4107NBY Membrane BCN_0507 ENOG4105CBC glutamate synthase BCN_0509 ENOG4108IUW ABC transporter BCN_0513 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCN_0514 ENOG4105G5W regulator Fur family BCN_0518 ENOG4108JQC penicillin-binding protein 1A BCN_0519 ENOG4108R9S DSBA oxidoreductase BCN_0521 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCN_0523 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCN_0524 ENOG4105BZU Histidine kinase BCN_0526 ENOG4105CYN Serine protein kinase BCN_0531 ENOG4105C94 Transporter BCN_0534 ENOG4105DZ6 Band 7 protein BCN_0536 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCN_0537 ENOG4108V9W transcriptional regulatory protein BCN_0538 ENOG4105D4T Citrate transporter BCN_0543 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCN_0544 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCN_0545 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCN_0546 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCN_0547 ENOG4105BZ7 extracellular solute-binding protein family 1 BCN_0548 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCN_0549 ENOG4108STX response regulator BCN_0550 ENOG4105US7 Histidine kinase BCN_0554 ENOG4108UZ3 Transporter BCN_0555 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCN_0557 ENOG4105BZU Histidine kinase BCN_0558 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_0561 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCN_0562 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCN_0563 ENOG4108JB9 formate dehydrogenase BCN_0568 ENOG4105CUB amino acid BCN_0570 ENOG4105C59 p-type ATPase BCN_0571 ENOG4105DAP Nicotinate phosphoribosyltransferase BCN_0578 ENOG41073R8 VanW family BCN_0579 ENOG4108KGH TRANSCRIPTIONal BCN_0580 ENOG4105D9N nucleoside BCN_0581 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCN_0582 ENOG4105C37 (CBS) domain BCN_0583 ENOG4108IJ0 Aspartate ammonia-lyase BCN_0584 ENOG4105DQ6 Transposase BCN_0586 ENOG4105DAA L-lactate BCN_0590 ENOG4105DUX Transporter BCN_0591 ENOG4108MES Periplasmic binding protein BCN_0592 ENOG4105DQ5 transport system permease protein BCN_0593 ENOG4108IHU transport system permease protein BCN_0594 ENOG4105E0A ABC, transporter BCN_0595 ENOG4105DMQ Methyltransferase BCN_0597 ENOG4105EXW epimerase dehydratase BCN_0598 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BCN_0600 ENOG4107T89 von Willebrand factor, type A BCN_0601 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCN_0602 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCN_0605 ENOG4105BZU Histidine kinase BCN_0606 ENOG4105D5Q Arginine ornithine antiporter BCN_0607 ENOG4107414 GntR family transcriptional regulator BCN_0608 ENOG4105C5Y PTS System BCN_0609 ENOG4105CG3 alpha amylase, catalytic region BCN_0613 ENOG4105E1K spore germination protein BCN_0614 ENOG4105CRN Aminoglycoside phosphotransferase BCN_0615 ENOG4105BZG amino acid carrier protein BCN_0616 ENOG4105CDA abc transporter atp-binding protein BCN_0617 ENOG4105CT1 (ABC) transporter BCN_0618 ENOG4105EAD ABC transporter BCN_0619 ENOG4105DRP amino acid AbC transporter BCN_0620 ENOG4108IQI permease BCN_0623 ENOG4105GFR rna polymerase sigma factor BCN_0625 ENOG4105D29 Helix-turn-helix type 11 domain protein BCN_0626 ENOG4105NAE bifunctional deaminase-reductase domain protein BCN_0627 ENOG4105BZU Histidine kinase BCN_0630 ENOG4105CHH sulfate transporter BCN_0631 ENOG41068KF Universal stress protein BCN_0633 ENOG4105DEF Extracellular solute-binding protein, family 5 BCN_0635 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCN_0636 ENOG4108JQ7 (ABC) transporter BCN_0638 ENOG4105CXY transporter BCN_0639 ENOG41067TZ transcriptional regulator, MarR family BCN_0640 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_0641 ENOG4105ETE Transcriptional regulator (LacI family BCN_0642 ENOG4108RVA ribokinase BCN_0644 ENOG4105C2J ABC transporter BCN_0645 ENOG4105CNN ABC, transporter BCN_0646 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCN_0647 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCN_0659 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCN_0660 ENOG41069ER domain protein BCN_0661 ENOG4105VZ8 Transcriptional regulator BCN_0662 ENOG4107D63 BCN_0665 ENOG4105DUX Transporter BCN_0669 ENOG4105C85 amino acid BCN_0670 ENOG4105C7N Xanthine uracil vitamin C permease BCN_0673 ENOG4105MA6 gCN5-related N-acetyltransferase BCN_0678 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCN_0679 ENOG4105E2S oxidase) subunit II BCN_0684 ENOG4106CAD Protein of unknown function (DUF3311) BCN_0685 ENOG4105E1V na solute symporter BCN_0688 ENOG4108NHD germination protein BCN_0690 ENOG4105CE1 Ferrous iron transport protein b BCN_0691 ENOG4105CE1 Ferrous iron transport protein b BCN_0692 ENOG4105CE1 Ferrous iron transport protein b BCN_0693 ENOG4105CVA phosphate BCN_0694 ENOG4105C8U phosphate abc transporter BCN_0695 ENOG4105E2Z phosphate ABC transporter (Permease BCN_0698 ENOG41080XQ Signal transduction protein with cbs domains BCN_0703 ENOG4105ETU transcriptional activator (TenA BCN_0705 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCN_0707 ENOG4108VEU Thiamine monophosphate synthase BCN_0708 ENOG41080HI glycine oxidase BCN_0711 ENOG4105D06 uba thif-type nad fad binding protein BCN_0712 ENOG4105DWF phosphomethylpyrimidine kinase BCN_0722 ENOG4108INS Transcriptional regulator BCN_0727 ENOG4105C19 ABC transporter BCN_0729 ENOG4105F5R ABC transporter BCN_0730 ENOG4105C2J ABC transporter BCN_0731 ENOG4108QGH periplasmic BCN_0733 ENOG4105C7N Xanthine uracil vitamin C permease BCN_0739 ENOG4105C5Y PTS System BCN_0746 ENOG4108B31 Spore germination protein BCN_0750 ENOG4107Y03 Nitroreductase BCN_0751 ENOG4105ED1 spovr family BCN_0757 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BCN_0758 ENOG4105XTG Pfam:DUF156 BCN_0759 ENOG4105VFE sira family BCN_0760 ENOG4107TPS domain protein BCN_0761 ENOG4105VFE sira family BCN_0762 ENOG4105VFE sira family BCN_0764 ENOG4105VFE sira family BCN_0766 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCN_0767 ENOG41087NI Sulfite exporter TauE/SafE BCN_0769 ENOG4108KGH TRANSCRIPTIONal BCN_0774 ENOG4105EMD TRANSCRIPTIONal BCN_0775 ENOG4105VCP PTS System BCN_0776 ENOG4105VZJ PTS System BCN_0781 ENOG41069ER domain protein BCN_0782 ENOG4107RBB ABC transporter, permease BCN_0783 ENOG4105C19 ABC transporter BCN_0789 ENOG4105WEF catalase BCN_0796 ENOG4107T5V SNARE associated Golgi BCN_0803 ENOG4105CUB amino acid BCN_0804 ENOG4107RWR Sodium hydrogen exchanger BCN_0806 ENOG4106KNT transcriptional regulator BCN_0814 ENOG4108YXU transcriptional regulator AsnC family BCN_0816 ENOG4105KPY Small multidrug resistance protein BCN_0817 ENOG4105KPY Small multidrug resistance protein BCN_0821 ENOG41082F9 transcriptional regulator BCN_0822 ENOG41061H0 Monooxygenase BCN_0823 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_0828 ENOG4106A3M Cytochrome p-450 BCN_0834 ENOG4105EWC Purine nucleoside phosphorylase BCN_0836 ENOG4105K8R UPF0145 protein BCN_0837 ENOG4105C5X domain protein BCN_0838 ENOG4105EKQ RNA-directed DNA polymerase BCN_0839 ENOG4105C5X domain protein BCN_0842 ENOG4105NF4 modulator of drug activity BCN_0843 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCN_0844 ENOG4105E5W Transporter BCN_0846 ENOG4107RKG DJ-1/PfpI family BCN_0848 ENOG4105D5Q Arginine ornithine antiporter BCN_0849 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BCN_0850 ENOG4105C26 Dehydrogenase BCN_0852 ENOG4105BZ1 (ABC) transporter BCN_0853 ENOG4105BZ1 (ABC) transporter BCN_0855 ENOG4105DRP amino acid AbC transporter BCN_0856 ENOG4105CDA abc transporter atp-binding protein BCN_0859 ENOG410839P BCN_0866 ENOG4107FQX Alpha-acetolactate decarboxylase BCN_0869 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCN_0870 ENOG4105D4P Coproporphyrinogen iii oxidase BCN_0873 ENOG4105EKQ RNA-directed DNA polymerase BCN_0876 ENOG4105CHH sulfate transporter BCN_0884 ENOG4106AKK s-layer domain-containing protein BCN_0886 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCN_0887 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCN_0890 ENOG4105CGU Enoyl-CoA hydratase BCN_0896 ENOG4105DER m42 family BCN_0908 ENOG4105CSH Transporter BCN_0910 ENOG4108MRH transcriptional regulatory protein BCN_0924 ENOG4105VTR Integrase BCN_0931 ENOG4105CDU Replicative dna helicase BCN_0936 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_0950 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCN_0953 ENOG4105CMT Dihydroxyacetone kinase BCN_0955 ENOG4105CMT Dihydroxyacetone kinase BCN_0959 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCN_0978 ENOG4105WN5 stage II sporulation protein BCN_0980 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_0982 ENOG4108MJI response regulator BCN_0983 ENOG4105BZU Histidine kinase BCN_0984 ENOG4105BZU Histidine kinase BCN_0989 ENOG4105K8R UPF0145 protein BCN_0997 ENOG4107VRP DNA repair exonuclease BCN_1000 ENOG4108IND Tetr family transcriptional regulator BCN_1001 ENOG4105EQ0 Major Facilitator superfamily BCN_1005 ENOG4108MUZ hydrolase BCN_1010 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCN_1013 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCN_1014 ENOG4105DQ6 Transposase BCN_1015 ENOG4105IYK transposase BCN_1018 ENOG4105EMN RNA polymerase sigma factor BCN_1020 ENOG4105CNI cell division protein FtsW BCN_1022 ENOG4105EEM helicase BCN_1023 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCN_1029 ENOG4105K59 histidine triad (HIT) protein BCN_1036 ENOG410905X membrane-flanked domain protein BCN_1037 ENOG4105CKV Membrane BCN_1043 ENOG410905X membrane-flanked domain protein BCN_1044 ENOG4105CKV Membrane BCN_1045 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCN_1046 ENOG4105BZ4 penicillin-binding protein BCN_1048 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCN_1049 ENOG4105C1Q protoporphyrinogen oxidase BCN_1055 ENOG4105ECB domain protein BCN_1060 ENOG4105D29 Helix-turn-helix type 11 domain protein BCN_1062 ENOG4106AXD BCN_1063 ENOG4108RQ5 Beta-lactamase domain-containing protein BCN_1064 ENOG4105DF9 Lipoate-protein, ligase BCN_1067 ENOG4105CEY Amp-dependent synthetase and ligase BCN_1070 ENOG4105CNA YD repeat protein BCN_1084 ENOG4105ENX hydrolase BCN_1085 ENOG4107RN3 metallophosphoesterase BCN_1087 ENOG4107TVP HD domain protein BCN_1089 ENOG4108AEY RNA polymerase sigma factor BCN_1090 ENOG41086D8 Transcriptional regulator BCN_1094 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCN_1099 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCN_1103 ENOG4105ZU5 s-layer protein BCN_1104 ENOG4107QP3 malate synthase g BCN_1107 ENOG4105VEQ Cold shock protein BCN_1110 ENOG4105XVF Competence transcription factor BCN_1124 ENOG4105ERH Fumarylacetoacetate hydrolase BCN_1129 ENOG4105CAQ asparagine synthetase BCN_1131 ENOG4105CH6 catalase BCN_1132 ENOG4105BZU Histidine kinase BCN_1138 ENOG4105QNR S1 RNA binding domain protein BCN_1139 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCN_1141 ENOG4107AYK membrAne BCN_1142 ENOG41073B9 BCN_1144 ENOG4108KP7 hydrolase BCN_1152 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCN_1153 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCN_1156 ENOG4105C31 Tryptophanyl-tRNA synthetase BCN_1159 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCN_1160 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCN_1162 ENOG4108JQ7 (ABC) transporter BCN_1163 ENOG4105UQX Mate efflux family protein BCN_1167 ENOG4108ZCF integral membrane protein BCN_1170 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCN_1172 ENOG4105DPN Oligoendopeptidase f BCN_1175 ENOG4108Z18 K06886 hemoglobin BCN_1176 ENOG4105MIX Adenylate cyclase BCN_1177 ENOG4106EFP UPF0738 protein BCN_1180 ENOG4105EMS pseudouridine synthase BCN_1185 ENOG4105K64 Glycosyl transferase, family 2 BCN_1189 ENOG4107TVC Glycosyl transferase, family 2 BCN_1193 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCN_1194 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCN_1196 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCN_1211 ENOG4105CK7 Sodium proline symporter BCN_1214 ENOG4105CRQ synthase (Component I) BCN_1215 ENOG4105DDQ anthranilate synthase BCN_1239 ENOG4105C7S Dehydrogenase BCN_1241 ENOG4105VZ8 Transcriptional regulator BCN_1251 ENOG4105DZ1 carboxypeptidase BCN_1252 ENOG4105VFR signal peptidase BCN_1259 ENOG4105C26 Dehydrogenase BCN_1261 ENOG4105F38 ABC transporter, permease BCN_1262 ENOG4105D38 putrescine abc transporter BCN_1263 ENOG4107RUE extracellular solute-binding protein family 1 BCN_1265 ENOG4105EYF MMPL domain protein BCN_1267 ENOG4108YBP pseudouridine synthase BCN_1269 ENOG4105K4I Scp-like extracellular BCN_1270 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCN_1271 ENOG4105CQB FAD linked oxidase domain protein BCN_1274 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_1275 ENOG4105BZU Histidine kinase BCN_1276 ENOG4105JXH GntR family transcriptional regulator BCN_1280 ENOG4106A3R peptidase BCN_1282 ENOG4108QTI )-transporter BCN_1283 ENOG4107TS3 membrane protein, TerC BCN_1284 ENOG4105CZN Potassium uptake protein BCN_1285 ENOG410681C small acid-soluble spore protein BCN_1286 ENOG4108Z7G MaoC domain protein dehydratase BCN_1290 ENOG4105CHR reductase BCN_1296 ENOG4105C4Y ABC transporter BCN_1297 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCN_1298 ENOG4107RCV ABC transporter, permease BCN_1302 ENOG4105E98 transcriptional regulator DeoR family BCN_1305 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCN_1307 ENOG4105PXI polysaccharide deacetylase BCN_1309 ENOG4105BZU Histidine kinase BCN_1310 ENOG41090MY MarR family Transcriptional regulator BCN_1312 ENOG4106DF1 BCN_1314 ENOG4105BZU Histidine kinase BCN_1316 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCN_1317 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCN_1326 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCN_1327 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCN_1328 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCN_1329 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCN_1330 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCN_1331 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCN_1332 ENOG4105CZV ABC transporter BCN_1334 ENOG4105CJ1 ABC, transporter BCN_1342 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCN_1343 ENOG4105EA8 2-Nitropropane dioxygenase BCN_1344 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCN_1346 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCN_1351 ENOG4105NQC Flavodoxin BCN_1359 ENOG4107QMU Mate efflux family protein BCN_1366 ENOG4105CZN Potassium uptake protein BCN_1367 ENOG41063Y9 BCN_1368 ENOG4105KBJ sporulation protein ytfj BCN_1374 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCN_1375 ENOG4105C7K acetolactate synthase BCN_1376 ENOG4108ZP8 Acetolactate synthase small subunit BCN_1391 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCN_1394 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCN_1395 ENOG4105E0M Sulfatase BCN_1397 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCN_1401 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCN_1402 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCN_1404 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCN_1405 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCN_1406 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCN_1407 ENOG4105C8J )-transporter BCN_1411 ENOG4105DFD Na H antiporter BCN_1415 ENOG4105ENE Histidine kinase BCN_1416 ENOG4105WH1 Two component transcriptional regulator luxr family BCN_1421 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCN_1431 ENOG4105CJ3 phosphate transporter BCN_1432 ENOG4107GRR phosphate transport regulator BCN_1433 ENOG4105BZ4 penicillin-binding protein BCN_1436 ENOG4105BZU Histidine kinase BCN_1437 ENOG4105I3N Conserved Protein BCN_1441 ENOG4105BZU Histidine kinase BCN_1447 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCN_1448 ENOG4105DZ1 carboxypeptidase BCN_1449 ENOG4108JIC nucleoside recognition domain protein BCN_1451 ENOG4105FE9 pseudouridine synthase BCN_1453 ENOG4107TWT Cytochrome c biogenesis protein BCN_1454 ENOG4105CRE cytochrome C BCN_1455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_1456 ENOG4105BZU Histidine kinase BCN_1457 ENOG4108WBT adenosyltransferase BCN_1458 ENOG41063SB peptidase BCN_1460 ENOG4108SAX Membrane BCN_1463 ENOG4105C9U ATP-dependent DNA helicase RecQ BCN_1464 ENOG4105I7S Abortive infection protein BCN_1466 ENOG4107RGJ metallophosphoesterase BCN_1467 ENOG4107X2D transcriptional regulator, merr family BCN_1468 ENOG4108S6Z Negative regulator of genetic competence BCN_1473 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCN_1474 ENOG4105HDK L-asparaginase BCN_1481 ENOG4105S2F BCN_1482 ENOG41065D1 BCN_1489 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCN_1492 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCN_1494 ENOG4105EAH synthase BCN_1498 ENOG4105CIH Imidazole acetol-phosphate transaminase BCN_1499 ENOG41068YB TPR repeat-containing protein BCN_1502 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCN_1503 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCN_1506 ENOG4105DQ6 Transposase BCN_1513 ENOG4108JYZ YitT family BCN_1514 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCN_1517 ENOG4105FJR Lmbe family BCN_1518 ENOG4105CPK Glycosyl transferase (Group 1 BCN_1526 ENOG4105DVT helicase BCN_1527 ENOG4105YAC BCN_1531 ENOG4105CSM endonuclease III BCN_1533 ENOG4105BZ4 penicillin-binding protein BCN_1544 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCN_1546 ENOG4105DVT helicase BCN_1547 ENOG4105CTD carboxy-peptidase BCN_1549 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCN_1551 ENOG4105C2W permease BCN_1552 ENOG4105DHF Membrane BCN_1554 ENOG410890F Dynamin family BCN_1556 ENOG4108W0I acetyltransferase BCN_1558 ENOG4105KHC sulfurtransferase BCN_1561 ENOG4106032 Glutathionylspermidine synthase BCN_1575 ENOG41081VK Ribonuclease BCN_1588 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCN_1590 ENOG4107RWR Sodium hydrogen exchanger BCN_1591 ENOG4105CN5 Metallo-Beta-Lactamase BCN_1592 ENOG4108Z5V transcriptional regulator, merr family BCN_1594 ENOG4105DQ6 Transposase BCN_1596 ENOG4105H67 Protein of unknown function (DUF421) BCN_1598 ENOG41080C8 DUF218 domain BCN_1605 ENOG4107Y80 Major Facilitator superfamily BCN_1611 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCN_1613 ENOG4107R0U MotA TolQ exbB proton channel BCN_1614 ENOG4105ER2 Ompa motb domain protein BCN_1615 ENOG4107YTP response regulator receiver protein BCN_1616 ENOG4105CBS Chea signal transduction histidine kinase BCN_1617 ENOG4105DD5 Flagellar motor switch protein BCN_1620 ENOG4105BZU Histidine kinase BCN_1624 ENOG4105E1Q flagellar hook-associated protein BCN_1625 ENOG4105DTJ flagellar hook-associated protein BCN_1626 ENOG4107TPX flagellar hook-associated BCN_1629 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCN_1630 ENOG4108ZC9 flagellar basal-body rod protein flgc BCN_1631 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCN_1632 ENOG4107U2N Flagellar M-ring protein BCN_1633 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCN_1639 ENOG4105BZE flagellar hook protein, FlgE BCN_1643 ENOG4107R88 Chemotaxis protein (CheV) BCN_1647 ENOG4105I03 Flagellin BCN_1648 ENOG4105I03 Flagellin BCN_1649 ENOG4105E4C Lytic transglycosylase catalytic BCN_1651 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCN_1652 ENOG4105DD5 Flagellar motor switch protein BCN_1654 ENOG4105CN7 Flagellar biosynthetic protein FliP BCN_1655 ENOG4105VS8 Flagellar biosynthetic protein fliq BCN_1657 ENOG4105D00 flagellar biosynthetic protein flhB BCN_1658 ENOG4105D7B Flagellar biosynthesis protein flha BCN_1659 ENOG4105FZW flagellar biosynthesis regulator FlhF BCN_1660 ENOG4105KTQ flagellar basal-body rod protein BCN_1661 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCN_1668 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCN_1672 ENOG4108U4N (sortase) family BCN_1677 ENOG4105DUM transcriptional regulator, lysR family BCN_1678 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCN_1680 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCN_1681 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BCN_1684 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BCN_1689 ENOG4105CVJ phosphoglycerate mutase BCN_1693 ENOG4105K56 Transcriptional regulator BCN_1695 ENOG4105CAQ asparagine synthetase BCN_1696 ENOG4105EKQ RNA-directed DNA polymerase BCN_1697 ENOG4105CAQ asparagine synthetase BCN_1701 ENOG4105PGM cation diffusion facilitator family transporter BCN_1703 ENOG4105DRR Transcriptional regulator, GntR family BCN_1704 ENOG4108UZ3 Transporter BCN_1706 ENOG4105DFD Na H antiporter BCN_1707 ENOG4105C9Q fumarate hydratase class II BCN_1710 ENOG4107QJQ Mate efflux family protein BCN_1711 ENOG4105EC3 peptidase S51, dipeptidase E BCN_1719 ENOG4106BRA Membrane BCN_1726 ENOG4105CJ1 ABC, transporter BCN_1730 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCN_1733 ENOG4108IJ0 Aspartate ammonia-lyase BCN_1734 ENOG4105C6K Malic enzyme BCN_1745 ENOG4105FVX BCN_1754 ENOG4105CSR polyphosphate kinase 2 BCN_1755 ENOG4105U3E Transcriptional regulator BCN_1757 ENOG4105DXI Major Facilitator superfamily BCN_1761 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCN_1763 ENOG4105EU0 Major facilitator Superfamily BCN_1764 ENOG4105C6T cysteine synthase BCN_1768 ENOG4105C8J )-transporter BCN_1770 ENOG4105X5K response regulator receiver protein BCN_1771 ENOG4105H67 Protein of unknown function (DUF421) BCN_1776 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCN_1777 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCN_1778 ENOG4105C7K acetolactate synthase BCN_1779 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BCN_1781 ENOG4105C7B Threonine dehydratase BCN_1786 ENOG4105C6X Major Facilitator BCN_1787 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCN_1789 ENOG4105DY9 regulatoR BCN_1790 ENOG4105CYC Transferase BCN_1794 ENOG4105F6J Alpha beta hydrolase fold BCN_1797 ENOG41068WN BCN_1798 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCN_1801 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCN_1805 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCN_1807 ENOG4105C0X amino acid BCN_1813 ENOG4107RHR regulatoR BCN_1815 ENOG4105D9N nucleoside BCN_1816 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCN_1820 ENOG4107RAQ aminopeptidase BCN_1830 ENOG4108T5E Copper resistance protein BCN_1831 ENOG4105KTB nuclear export factor GLE1 BCN_1832 ENOG4107RT3 EamA-like transporter family BCN_1833 ENOG4105GZI Transcriptional regulator BCN_1834 ENOG4108Z40 Transcriptional regulator BCN_1835 ENOG4107ZXU DSBA oxidoreductase BCN_1836 ENOG4108TVJ Nitroreductase BCN_1838 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCN_1839 ENOG4106F5Q Membrane BCN_1840 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCN_1842 ENOG4105CKI cobalamin synthesis protein BCN_1844 ENOG4105C0Z ABC transporter BCN_1845 ENOG4108IV0 ABC, transporter BCN_1846 ENOG4105C32 Amino acid ABC transporter (Permease) BCN_1848 ENOG4105SKE transcriptional Regulator LysR family BCN_1850 ENOG4105MDS 4-oxalocrotonate tautomerase BCN_1854 ENOG4105C4M (Ubiquinol oxidase) subunit I BCN_1855 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCN_1856 ENOG4108JJ9 ABC, transporter BCN_1857 ENOG4108JJ8 (ABC) transporter BCN_1859 ENOG4105K64 Glycosyl transferase, family 2 BCN_1861 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCN_1866 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCN_1872 ENOG4105BZ1 (ABC) transporter BCN_1873 ENOG4105EFI regulatoR BCN_1874 ENOG4105BZU Histidine kinase BCN_1880 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCN_1881 ENOG4108ZJ4 polysaccharide deacetylase BCN_1887 ENOG4105D6E homoserine dehydrogenase BCN_1892 ENOG4108KGH TRANSCRIPTIONal BCN_1893 ENOG4107VMI polysaccharide deacetylase BCN_1895 ENOG4105KT7 mgtC SapB transporter BCN_1896 ENOG4105VRR gCN5-related N-acetyltransferase BCN_1897 ENOG4105YWU small acid-soluble spore protein BCN_1899 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCN_1900 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCN_1910 ENOG4105KRN Transcriptional regulator, abrb family BCN_1915 ENOG4108KB1 transcriptional regulator, arac family BCN_1917 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BCN_1918 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BCN_1919 ENOG4105CT8 Phosphorylase BCN_1920 ENOG4105DKQ ROK family BCN_1921 ENOG4105E70 isomerase BCN_1922 ENOG4105CE4 GlcNAc 6-P deacetylase BCN_1923 ENOG4105DE4 1-phosphofructokinase BCN_1924 ENOG4105D2M Aldolase BCN_1925 ENOG4105ESP cell wall surface anchor family protein BCN_1926 ENOG4105ESP cell wall surface anchor family protein BCN_1927 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BCN_1928 ENOG4105YVS arsR family transcriptional regulator BCN_1929 ENOG4105CPC Aldo Keto reductase BCN_1930 ENOG4107XZQ multidrug resistance protein BCN_1935 ENOG4105C8Q Methyl-accepting chemotaxis BCN_1939 ENOG4108K88 Membrane BCN_1940 ENOG4108WPJ Ferritin-like domain BCN_1943 ENOG4105DEN Luciferase family BCN_1946 ENOG4105VMI -acetyltransferase BCN_1947 ENOG4107QM2 Aldo Keto reductase BCN_1948 ENOG4105CKI cobalamin synthesis protein BCN_1950 ENOG4105DSE periplasmic solute binding protein BCN_1952 ENOG4105K4T epimerase BCN_1954 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCN_1963 ENOG4107T5V SNARE associated Golgi BCN_1966 ENOG4108PJD permease BCN_1968 ENOG4108S4H thioesterase Superfamily protein BCN_1969 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCN_1973 ENOG4105SXS Protein of unknown function (DUF456) BCN_1974 ENOG4105C37 (CBS) domain BCN_1978 ENOG4108Z7R Chaperone CsaA BCN_1982 ENOG4108ZRV stage ii sporulation protein p BCN_1984 ENOG4108VXD carboxy-peptidase BCN_1986 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCN_1991 ENOG4108X4Q Hydrolase BCN_1993 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCN_1994 ENOG4107RBS Methyltransferase BCN_1997 ENOG41087PP glycosyltransferase MGT family BCN_1998 ENOG4108JYZ YitT family BCN_1999 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCN_2005 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCN_2010 ENOG4105KBJ sporulation protein ytfj BCN_2015 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCN_2019 ENOG4105VTR Integrase BCN_2022 ENOG41067QW Transcriptional regulator BCN_2030 ENOG4105KRN Transcriptional regulator, abrb family BCN_2043 ENOG410682Q Phage transcriptional regulator, ArpU BCN_2050 ENOG4105CAR Terminase, large subunit BCN_2052 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCN_2076 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCN_2077 ENOG4105EMN RNA polymerase sigma factor BCN_2080 ENOG4105CNW domain protein BCN_2082 ENOG4108V06 Glutathione peroxidase BCN_2085 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCN_2087 ENOG4108IUE nitrate reductase beta subunit BCN_2088 ENOG4105R3A Nitrate reductase BCN_2090 ENOG4107V6Q Cyclic nucleotide-binding domain BCN_2092 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCN_2093 ENOG4105D06 uba thif-type nad fad binding protein BCN_2094 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCN_2095 ENOG4108ZAF Molybdopterin BCN_2101 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCN_2102 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCN_2103 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCN_2104 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BCN_2105 ENOG4108IFG nitrite reductase, (NAD(P)H) BCN_2106 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BCN_2113 ENOG4105MCT stage V sporulation protein S BCN_2118 ENOG4105C5H ABC transporter BCN_2121 ENOG4108UUM single-stranded DNA-binding protein BCN_2127 ENOG4107YX5 Pfam:DUF548 BCN_2140 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCN_2142 ENOG4105C5S asparaginyl-tRNA synthetase BCN_2143 ENOG4105C8J )-transporter BCN_2147 ENOG4107XGZ Hydrolase BCN_2148 ENOG4105CY2 Citrate transporter BCN_2149 ENOG4105C0A alcohol dehydrogenase BCN_2152 ENOG4105KD7 acetyltransferase BCN_2153 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCN_2158 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCN_2161 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCN_2165 ENOG4107RVG penicillin-binding protein BCN_2166 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BCN_2167 ENOG4105E9Q Acyl-transferase BCN_2168 ENOG4108UT2 hemolysin iii BCN_2171 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCN_2174 ENOG4108RCR degv family BCN_2175 ENOG4105E8R UPF0173 metal-dependent hydrolase BCN_2176 ENOG4108KF3 Electron transport protein SCO1 SenC BCN_2177 ENOG4107Y70 Heat shock protein BCN_2178 ENOG4105CAQ asparagine synthetase BCN_2183 ENOG4108MES Periplasmic binding protein BCN_2184 ENOG4105F0I Aminotransferase BCN_2191 ENOG4105D8X mechanosensitive ion channel BCN_2192 ENOG4105BZU Histidine kinase BCN_2193 ENOG4105WH1 Two component transcriptional regulator luxr family BCN_2195 ENOG4106KNT transcriptional regulator BCN_2208 ENOG4108IJ8 ABC transporter BCN_2209 ENOG4105E90 ABC transporter BCN_2216 ENOG4105C37 (CBS) domain BCN_2222 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCN_2225 ENOG4107S4Y M20 DapE family protein YgeY BCN_2226 ENOG4108TSC N-acetyltransferase BCN_2227 ENOG4108JUB Transcriptional regulator BCN_2228 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCN_2236 ENOG4108N23 SpoOM-related protein BCN_2237 ENOG410841Q phosphoesterase PA-phosphatase related protein BCN_2239 ENOG4105SZ6 Thioredoxin BCN_2248 ENOG4108AEY RNA polymerase sigma factor BCN_2255 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCN_2267 ENOG4105BZ4 penicillin-binding protein BCN_2269 ENOG4105CZM Major Facilitator BCN_2270 ENOG4105W8X HesB YadR YfhF-family protein BCN_2272 ENOG4105DXD 2-methylcitrate dehydratase BCN_2273 ENOG4105CR4 methylisocitrate lyase BCN_2274 ENOG4105C1G acyl-Coa dehydrogenase BCN_2275 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCN_2277 ENOG4105N14 lysine exporter protein LysE YggA BCN_2278 ENOG4105E39 Enoyl-CoA hydratase BCN_2281 ENOG4107RFY SbcCD D subunit BCN_2288 ENOG4105FCD Major Facilitator BCN_2289 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCN_2290 ENOG4105E4F Isochorismate synthase BCN_2291 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCN_2292 ENOG4105WQI isochorismatase BCN_2293 ENOG4105CEY Amp-dependent synthetase and ligase BCN_2295 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_2298 ENOG4105K70 DNA-binding protein BCN_2302 ENOG4105BZG amino acid carrier protein BCN_2309 ENOG4105FE9 pseudouridine synthase BCN_2310 ENOG4105C22 threonyL-tRNA synthetase BCN_2311 ENOG4105C19 ABC transporter BCN_2318 ENOG4108D32 Methyltransferase BCN_2323 ENOG41081I9 integral membrane protein BCN_2328 ENOG4105EYF MMPL domain protein BCN_2333 ENOG4105WCN acetyltransferase BCN_2338 ENOG4105C1Q protoporphyrinogen oxidase BCN_2340 ENOG41068WN BCN_2345 ENOG410667J hydrolase BCN_2349 ENOG4107V2S Transcriptional regulator BCN_2350 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCN_2353 ENOG4105DND Transcriptional regulator BCN_2354 ENOG4108RPX mosc domain containing protein BCN_2357 ENOG4105BZ1 (ABC) transporter BCN_2358 ENOG4105BZ1 (ABC) transporter BCN_2361 ENOG4108JCI Transcriptional regulator BCN_2368 ENOG4108KPJ rna polymerase sigma factor BCN_2373 ENOG4105F32 YngK protein BCN_2378 ENOG4105RD7 BadF BadG BcrA BcrD BCN_2380 ENOG4107STF Involved in phosphonate degradation (By similarity) BCN_2385 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BCN_2387 ENOG4105C1J atp-dependent rna helicase BCN_2392 ENOG4108RZE Tetr family transcriptional regulator BCN_2396 ENOG41088CC tellurite resistance protein tehB BCN_2398 ENOG4107RA9 decarboxylase BCN_2405 ENOG4105CIN aminoacyl-histidine dipeptidase BCN_2410 ENOG4107RF6 penicillin-binding protein BCN_2411 ENOG4107RF6 penicillin-binding protein BCN_2413 ENOG4105DIN metallophosphoesterase BCN_2415 ENOG4105CJ1 ABC, transporter BCN_2417 ENOG4107Z3H Transcriptional regulator, TetR family BCN_2420 ENOG4105C1G acyl-Coa dehydrogenase BCN_2421 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCN_2422 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCN_2423 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCN_2424 ENOG4105E39 Enoyl-CoA hydratase BCN_2425 ENOG4107QX3 carboxylase BCN_2426 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCN_2429 ENOG4105DBI uridine monophosphokinase BCN_2434 ENOG4105T9C HD domain BCN_2436 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCN_2445 ENOG4105FQP Beta-lactamase BCN_2447 ENOG4107Y80 Major Facilitator superfamily BCN_2449 ENOG41089UC methyltransferase, type 11 BCN_2457 ENOG4105CPQ Dehydrogenase BCN_2459 ENOG410900G Protein of unknown function (DUF421) BCN_2460 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCN_2461 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCN_2462 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCN_2464 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BCN_2466 ENOG4105DK7 lysyl-tRNA synthetase BCN_2478 ENOG4105D6E homoserine dehydrogenase BCN_2481 ENOG4105ETU transcriptional activator (TenA BCN_2499 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCN_2501 ENOG4107EV6 Inherit from COG: YD repeat protein BCN_2515 ENOG410667J hydrolase BCN_2517 ENOG4105BZU Histidine kinase BCN_2518 ENOG4107RF6 penicillin-binding protein BCN_2525 ENOG4108HGU Histidine kinase BCN_2527 ENOG4105RHY Pfam:UPF0157 BCN_2528 ENOG4105CB2 alcohol dehydrogenase BCN_2529 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCN_2530 ENOG4105CJN penicillin-binding protein BCN_2531 ENOG4108IG5 Transcriptional regulator BCN_2532 ENOG4105CHR reductase BCN_2545 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCN_2550 ENOG4107Y9U Membrane BCN_2552 ENOG4105EGD dinuclear metal center protein, YbgI family BCN_2557 ENOG4105FCD Major Facilitator BCN_2560 ENOG4105E09 nadh pyrophosphatase BCN_2561 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCN_2562 ENOG4108Z4K mutator MutT protein BCN_2567 ENOG4108XI2 Domain of unknown function (DUF1963) BCN_2572 ENOG4108NRW Phospholipase, patatin family BCN_2573 ENOG4105KWG Pfam:DUF1696 BCN_2580 ENOG4105PKS Excinuclease abc c subunit domain protein BCN_2586 ENOG4107VFR oxidoreductase BCN_2591 ENOG4105U0R haloacid dehalogenase-like hydrolase BCN_2595 ENOG4108IUM Glycogen debranching enzyme BCN_2599 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCN_2600 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCN_2611 ENOG4105MSI germination protein ypeb BCN_2619 ENOG4107Z3H Transcriptional regulator, TetR family BCN_2625 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCN_2629 ENOG4105E98 transcriptional regulator DeoR family BCN_2633 ENOG4107QKR Dehydrogenase BCN_2635 ENOG4107RUY (E1 component), alpha subunit BCN_2637 ENOG4105E1F short-chain dehydrogenase reductase BCN_2638 ENOG4105RHY Pfam:UPF0157 BCN_2639 ENOG4105DBI uridine monophosphokinase BCN_2646 ENOG4107SQ8 Glycine betaine BCN_2647 ENOG4108IJ7 Glycine betaine BCN_2652 ENOG4105E66 phosphoriboisomerase A BCN_2653 ENOG41082BV acetyltransferase BCN_2654 ENOG4108M1A Chitin-binding protein BCN_2656 ENOG41087PP glycosyltransferase MGT family BCN_2660 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCN_2661 ENOG4105MSB protein, conserved in bacteria BCN_2663 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCN_2667 ENOG4108Z7F N-acetyltransferase BCN_2671 ENOG4105EEM helicase BCN_2675 ENOG4105C9U ATP-dependent DNA helicase RecQ BCN_2687 ENOG4108M1A Chitin-binding protein BCN_2692 ENOG4105BZG amino acid carrier protein BCN_2693 ENOG4105C26 Dehydrogenase BCN_2694 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCN_2695 ENOG4105CTU Proline racemase BCN_2696 ENOG4105CTU Proline racemase BCN_2697 ENOG41080HI glycine oxidase BCN_2699 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCN_2705 ENOG4107T5V SNARE associated Golgi BCN_2706 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCN_2707 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BCN_2710 ENOG4105DTQ mandelate racemase muconate lactonizing BCN_2719 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCN_2720 ENOG4105BZU Histidine kinase BCN_2721 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_2725 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BCN_2728 ENOG4105DPN Oligoendopeptidase f BCN_2729 ENOG4105EPR degv family BCN_2742 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCN_2743 ENOG4106K7D Major facilitator family transporter BCN_2748 ENOG4107BMA Transglycosylase associated protein BCN_2751 ENOG41089UC methyltransferase, type 11 BCN_2758 ENOG4105CHM Aminotransferase BCN_2761 ENOG4108ZMI UPF0477 protein BCN_2772 ENOG4105C02 permease BCN_2775 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCN_2776 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCN_2777 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCN_2786 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCN_2795 ENOG4107VC0 DNA alkylation repair enzyme BCN_2797 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_2798 ENOG4107VMI polysaccharide deacetylase BCN_2800 ENOG4108ZCF integral membrane protein BCN_2801 ENOG4105E0M Sulfatase BCN_2802 ENOG4105C5H ABC transporter BCN_2804 ENOG4105EYF MMPL domain protein BCN_2805 ENOG41082JN Transcriptional regulator BCN_2809 ENOG4105CIH Imidazole acetol-phosphate transaminase BCN_2811 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCN_2817 ENOG41069ER domain protein BCN_2820 ENOG4105D4B ABC, transporter BCN_2822 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCN_2824 ENOG4105DKT Transcriptional regulator BCN_2825 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BCN_2827 ENOG41061GT Aldolase BCN_2829 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCN_2835 ENOG4105II7 pyrroline-5-carboxylate reductase BCN_2837 ENOG4107258 Transcriptional regulator BCN_2839 ENOG4105E0Y RtcB Protein BCN_2840 ENOG4105ECK Fatty Acid Desaturase BCN_2842 ENOG4105G6Z alkaline phosphatase BCN_2844 ENOG4105VMP Transcriptional regulator BCN_2847 ENOG41090T1 Membrane BCN_2849 ENOG4108WCX response regulator BCN_2851 ENOG4105KNA -acetyltransferase BCN_2856 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCN_2860 ENOG4105C8Y Acetylornithine aminotransferase BCN_2862 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCN_2866 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCN_2873 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCN_2875 ENOG4108TVJ Nitroreductase BCN_2876 ENOG4105FS7 Transcriptional regulator BCN_2883 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCN_2886 ENOG4105C19 ABC transporter BCN_2891 ENOG4108DMH HTH_ARAC BCN_2892 ENOG4108XET gCN5-related N-acetyltransferase BCN_2895 ENOG4108PCN EamA-like transporter family BCN_2904 ENOG410635A Membrane BCN_2905 ENOG4105KNA -acetyltransferase BCN_2906 ENOG4108IQI permease BCN_2908 ENOG4105F1N DNA alkylation repair BCN_2916 ENOG4107RF6 penicillin-binding protein BCN_2924 ENOG4105P4J Allophanate hydrolase, subunit 1 BCN_2925 ENOG4107258 Transcriptional regulator BCN_2927 ENOG4106N3A copper homeostasis protein cutc BCN_2928 ENOG4108ZRV stage ii sporulation protein p BCN_2929 ENOG4108ZHR arsR family transcriptional regulator BCN_2931 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_2932 ENOG4105FDT acyl-CoA dehydrogenase BCN_2936 ENOG4105DWD nucleoside recognition domain protein BCN_2943 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCN_2959 ENOG4105E2A Dehydrogenase BCN_2961 ENOG4108IJ0 Aspartate ammonia-lyase BCN_2962 ENOG4108IJ0 Aspartate ammonia-lyase BCN_2963 ENOG4105HDK L-asparaginase BCN_2964 ENOG4108IMY Transcriptional regulator BCN_2965 ENOG4105DQ6 Transposase BCN_2966 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCN_2967 ENOG4105CUB amino acid BCN_2968 ENOG4105II7 pyrroline-5-carboxylate reductase BCN_2969 ENOG4108NHD germination protein BCN_2970 ENOG4108Q8B Spore germination protein BCN_2975 ENOG4105CSV Glutaminase BCN_2981 ENOG4107QJQ Mate efflux family protein BCN_2982 ENOG4107QTZ amino acid BCN_2983 ENOG4105CGH 5'-nucleotidase BCN_2984 ENOG4105CH6 catalase BCN_2993 ENOG4108606 TspO/MBR family BCN_2994 ENOG4105CVP deoxyribo-dipyrimidine photolyase BCN_2999 ENOG4108TWJ NADH dehydrogenase subunit 5 BCN_3000 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCN_3003 ENOG4105E1K spore germination protein BCN_3005 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCN_3012 ENOG4105DET Rhamnulokinase BCN_3013 ENOG4105MP9 class II Aldolase BCN_3015 ENOG4105CNN ABC, transporter BCN_3017 ENOG4105NWF RbsD or FucU transport BCN_3018 ENOG4105ETE Transcriptional regulator (LacI family BCN_3020 ENOG4105D6J arsenicaL-resistance protein BCN_3021 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_3022 ENOG41085FC arsR family transcriptional regulator BCN_3025 ENOG4105NAE bifunctional deaminase-reductase domain protein BCN_3028 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCN_3033 ENOG4107P5I polyketide synthase BCN_3034 ENOG4108IG5 Transcriptional regulator BCN_3035 ENOG4105F27 Major Facilitator BCN_3036 ENOG4105M4P Tetr family transcriptional regulator BCN_3037 ENOG4105CHR reductase BCN_3038 ENOG4108YXU transcriptional regulator AsnC family BCN_3044 ENOG4105N0V mono-oxygenase ydhR BCN_3047 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCN_3048 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_3060 ENOG4105K6H D-cysteine desulfhydrase BCN_3062 ENOG4105C88 aminopeptidase BCN_3065 ENOG4105W1Y Transcriptional regulator BCN_3066 ENOG4105JQZ Methyltransferase BCN_3070 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCN_3074 ENOG4105BZU Histidine kinase BCN_3077 ENOG4108U05 Transcriptional regulator BCN_3078 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BCN_3080 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCN_3085 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCN_3088 ENOG4108JQ1 Dehydrogenase BCN_3092 ENOG41082W1 Cupin 2, conserved barrel domain protein BCN_3093 ENOG410874W AraC family transcriptional regulator BCN_3098 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCN_3106 ENOG4108ISG Major Facilitator BCN_3109 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCN_3110 ENOG4105CZM Major Facilitator BCN_3114 ENOG4105DA5 (ABC) transporter BCN_3115 ENOG41069JR BCN_3117 ENOG4105RXJ BCN_3118 ENOG4105KPY Small multidrug resistance protein BCN_3119 ENOG4105KBX Transcriptional regulator, TetR family BCN_3120 ENOG4107AUC BCN_3122 ENOG4105CRW Short chain fatty acid transporter BCN_3124 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCN_3131 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCN_3139 ENOG4107TXC Transcriptional regulator BCN_3143 ENOG4105EKQ RNA-directed DNA polymerase BCN_3144 ENOG4105RHY Pfam:UPF0157 BCN_3146 ENOG4108Z66 YbaK ebsC protein BCN_3150 ENOG4105KVH Transcriptional regulator BCN_3151 ENOG4108RCM Nitroreductase BCN_3156 ENOG4108PSK reductase BCN_3158 ENOG4105CJ1 ABC, transporter BCN_3168 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_3169 ENOG4105DKQ ROK family BCN_3170 ENOG4108UW5 maltose o-acetyltransferase BCN_3171 ENOG4105C31 Tryptophanyl-tRNA synthetase BCN_3179 ENOG4105DMQ Methyltransferase BCN_3181 ENOG4105EV4 Multidrug resistance protein mdtH BCN_3186 ENOG4105C37 (CBS) domain BCN_3189 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCN_3190 ENOG4105FAW cDP-glucose 4,6-dehydratase BCN_3196 ENOG4105DDN Pentapeptide repeat-containing protein BCN_3197 ENOG4105XDF Protein of unknown function (DUF1272) BCN_3198 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCN_3199 ENOG4105CMG Carbohydrate kinase BCN_3200 ENOG4105C6Z Gluconate BCN_3201 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCN_3204 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCN_3205 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCN_3206 ENOG4105CIS alcohol dehydrogenase BCN_3207 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BCN_3210 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BCN_3213 ENOG4105CV8 reductase BCN_3214 ENOG4105F27 Major Facilitator BCN_3217 ENOG4105C44 Serine transporter BCN_3218 ENOG4105EKQ RNA-directed DNA polymerase BCN_3225 ENOG4105KVH Transcriptional regulator BCN_3226 ENOG4108TZY GntR Family Transcriptional Regulator BCN_3227 ENOG4105D9R oxidoreductase BCN_3228 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCN_3229 ENOG4105KVH Transcriptional regulator BCN_3230 ENOG4105KVH Transcriptional regulator BCN_3238 ENOG4105JAB phenazine biosynthesis protein, phzf family BCN_3240 ENOG4105CHR reductase BCN_3244 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCN_3245 ENOG4105KVH Transcriptional regulator BCN_3248 ENOG4108ZJ4 polysaccharide deacetylase BCN_3261 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCN_3270 ENOG4105H3G oxidoreductase BCN_3279 ENOG4105K7K Transcriptional regulator BCN_3280 ENOG4105CIS alcohol dehydrogenase BCN_3287 ENOG4108TN2 lmbE family BCN_3289 ENOG4107R3E Citrate transporter BCN_3291 ENOG4108MES Periplasmic binding protein BCN_3292 ENOG4105EHG Permease protein BCN_3293 ENOG4105DQ5 transport system permease protein BCN_3294 ENOG4105NX3 Membrane BCN_3298 ENOG4107CUJ Protein of unknown function (DUF2690) BCN_3300 ENOG4107V2S Transcriptional regulator BCN_3304 ENOG4105C98 muts2 protein BCN_3305 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCN_3306 ENOG4105DPN Oligoendopeptidase f BCN_3307 ENOG4108A04 Beta-lactamase BCN_3312 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCN_3314 ENOG41082BM Transcriptional regulator, arsr family BCN_3315 ENOG4105CIS alcohol dehydrogenase BCN_3317 ENOG4107JM4 Tetratricopeptide repeat BCN_3320 ENOG4105RHY Pfam:UPF0157 BCN_3322 ENOG4105C09 Bile acid BCN_3323 ENOG4105CQB FAD linked oxidase domain protein BCN_3328 ENOG4105KT7 mgtC SapB transporter BCN_3331 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_3332 ENOG4105EAB amino acid AbC transporter BCN_3334 ENOG4108HW4 amino acid AbC transporter BCN_3336 ENOG41073R8 VanW family BCN_3338 ENOG4108R1P BCN_3342 ENOG4105VEQ Cold shock protein BCN_3346 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCN_3350 ENOG410904N short-chain dehydrogenase reductase BCN_3352 ENOG4106IQC argininosuccinate lyase BCN_3355 ENOG4108IA2 Sodium pantothenate symporter BCN_3357 ENOG4105C26 Dehydrogenase BCN_3365 ENOG4105CHR reductase BCN_3367 ENOG4105EWU Squalene--hopene cyclase BCN_3369 ENOG4105FR1 rard protein BCN_3370 ENOG410696E Membrane BCN_3373 ENOG4105D1F ATP-binding protein BCN_3375 ENOG4108ZAF Molybdopterin BCN_3376 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCN_3377 ENOG4105D06 uba thif-type nad fad binding protein BCN_3378 ENOG4105TMB Formate nitrite transporter BCN_3381 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCN_3382 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCN_3384 ENOG4108JB9 formate dehydrogenase BCN_3385 ENOG4105E1K spore germination protein BCN_3397 ENOG4107QJT sodium dicarboxylate symporter BCN_3398 ENOG4108KGH TRANSCRIPTIONal BCN_3400 ENOG4105EMN RNA polymerase sigma factor BCN_3403 ENOG4105CIG ABC transporter BCN_3405 ENOG4105D9R oxidoreductase BCN_3407 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCN_3409 ENOG4105K4P CoA-binding domain protein BCN_3410 ENOG4105C0H protease BCN_3411 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_3413 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCN_3415 ENOG4105W8X HesB YadR YfhF-family protein BCN_3421 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCN_3422 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCN_3423 ENOG4105BZ1 (ABC) transporter BCN_3424 ENOG4108I0Z Aconitate hydratase BCN_3430 ENOG4105E5W Transporter BCN_3435 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCN_3442 ENOG4107F3J Amp-dependent synthetase and ligase BCN_3443 ENOG4107ZYJ bioY protein BCN_3444 ENOG4105CEY Amp-dependent synthetase and ligase BCN_3447 ENOG4108IMY Transcriptional regulator BCN_3456 ENOG4107AYK membrAne BCN_3458 ENOG4105BZU Histidine kinase BCN_3459 ENOG4105FBA Phospholipase Carboxylesterase BCN_3460 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCN_3461 ENOG4105CK7 Sodium proline symporter BCN_3463 ENOG4105CBC glutamate synthase BCN_3464 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCN_3465 ENOG4108VJ1 Transcriptional regulator (CarD family BCN_3466 ENOG4108903 Formimidoylglutamase BCN_3471 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BCN_3481 ENOG4105EKQ RNA-directed DNA polymerase BCN_3486 ENOG4107QIV Cytochrome c biogenesis protein BCN_3488 ENOG4105CH2 amidohydrolase BCN_3490 ENOG4105CJ1 ABC, transporter BCN_3492 ENOG4107RSM transcriptional regulator BCN_3494 ENOG41067MG lrgb family BCN_3499 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCN_3502 ENOG4105BZ1 (ABC) transporter BCN_3503 ENOG4105BZ1 (ABC) transporter BCN_3521 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCN_3527 ENOG4105D5T phosphonate abc transporter BCN_3528 ENOG4108HW3 (ABC) transporter BCN_3529 ENOG4105CGH 5'-nucleotidase BCN_3531 ENOG4108SVB resolvase BCN_3535 ENOG4105K7K Transcriptional regulator BCN_3536 ENOG4105C5F glutamine synthetase BCN_3537 ENOG4105KV4 Transcriptional regulator BCN_3538 ENOG4105CXI aluminum resistance protein BCN_3539 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCN_3540 ENOG4105EN6 Membrane BCN_3541 ENOG4106F1P AAA ATPase, central domain protein BCN_3547 ENOG41069ER domain protein BCN_3548 ENOG4105DM4 PTS System BCN_3549 ENOG4105DE4 1-phosphofructokinase BCN_3550 ENOG4105E98 transcriptional regulator DeoR family BCN_3551 ENOG4107QW4 alcohol dehydrogenase BCN_3552 ENOG4108SJC Membrane BCN_3554 ENOG4105C85 amino acid BCN_3557 ENOG4105TMB Formate nitrite transporter BCN_3558 ENOG4105K70 DNA-binding protein BCN_3559 ENOG4105C59 p-type ATPase BCN_3560 ENOG410681U heavy metal transport detoxification protein BCN_3561 ENOG4105VPX protein, conserved in bacteria BCN_3563 ENOG4105NIV Esterase BCN_3564 ENOG4105E0A ABC, transporter BCN_3569 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCN_3570 ENOG4105D03 DNA-3-methyladenine glycosylase II BCN_3574 ENOG4105BZU Histidine kinase BCN_3583 ENOG4105F0V Cell wall hydrolase BCN_3584 ENOG4105E0M Sulfatase BCN_3585 ENOG410890F Dynamin family BCN_3588 ENOG4107QHE Choloylglycine hydrolase BCN_3593 ENOG4105DA5 (ABC) transporter BCN_3601 ENOG4105DQU oxidoreductase, subunit beta BCN_3602 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCN_3603 ENOG4108IGT Dipeptidase BCN_3604 ENOG4105MCT stage V sporulation protein S BCN_3605 ENOG4105D48 metallophosphoesterase BCN_3606 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) BCN_3610 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCN_3613 ENOG4105XZV Protein of unknown function (DUF3243) BCN_3614 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCN_3618 ENOG4105UIB (ABC) transporter BCN_3619 ENOG4108JQ9 ABC transporter BCN_3620 ENOG4105DIH basic membrane BCN_3621 ENOG4105FDP GntR family transcriptional regulator BCN_3622 ENOG4107QZI cell division protein FtsK BCN_3624 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCN_3627 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCN_3629 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCN_3630 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCN_3631 ENOG4105E35 Dipicolinate synthase subunit A BCN_3633 ENOG4105C1V Peptidase, M16 BCN_3637 ENOG4105DTN riboflavin biosynthesis protein ribF BCN_3640 ENOG4105W7A Protein of unknown function (DUF503) BCN_3642 ENOG4105VHM ribosomal protein BCN_3643 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCN_3644 ENOG4105CHV Transcription elongation factor NusA BCN_3646 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCN_3649 ENOG4105DZP Membrane-associated zinc metalloprotease BCN_3651 ENOG4105KNE Phosphatidate cytidylyltransferase BCN_3660 ENOG4108HE4 integrase family BCN_3662 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCN_3663 ENOG4105C79 DNA protecting protein DprA BCN_3664 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCN_3667 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCN_3672 ENOG4105VB6 UPF0109 protein BCN_3676 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCN_3677 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCN_3680 ENOG4105CHR reductase BCN_3681 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCN_3684 ENOG4105CB5 ATP-dependent DNA helicase recG BCN_3685 ENOG4105DP4 dak2 domain fusion protein ylov BCN_3686 ENOG4108ZAA Alkaline-shock protein BCN_3688 ENOG4105FJ0 thiamine BCN_3689 ENOG4105DJV ribulose-phosphate 3-epimerase BCN_3691 ENOG4105D9P serine threonine protein kinase BCN_3692 ENOG4108ZF3 Phosphatase BCN_3694 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCN_3696 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCN_3697 ENOG4105C25 Primosomal protein n' BCN_3698 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCN_3702 ENOG4105DSJ YicC domain protein BCN_3704 ENOG4105F23 Fibronectin-binding protein BCN_3705 ENOG4105DC7 peptidase M24 BCN_3724 ENOG4105C34 Pseudouridine synthase BCN_3729 ENOG4105DBK s4 domain protein BCN_3730 ENOG41067XK integral membrane protein BCN_3732 ENOG4105DFA alanine racemase domain protein BCN_3733 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCN_3734 ENOG4105WR5 sporulation protein, YlmC YmxH family BCN_3736 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_3738 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCN_3739 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCN_3740 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BCN_3743 ENOG4105CNI cell division protein FtsW BCN_3746 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCN_3747 ENOG4105CJN penicillin-binding protein BCN_3748 ENOG4105CJN penicillin-binding protein BCN_3749 ENOG41068DC Essential cell division protein (By similarity) BCN_3756 ENOG4105KNH Nucleic acid-binding protein BCN_3782 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCN_3784 ENOG4105CAR Terminase, large subunit BCN_3811 ENOG4108IMY Transcriptional regulator BCN_3819 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BCN_3821 ENOG41063PX domain protein BCN_3822 ENOG4105D78 K07001 NTE family protein BCN_3823 ENOG4105H20 Sporulation integral membrane protein YlbJ BCN_3825 ENOG4106H78 methyltransferase BCN_3827 ENOG4105DQ6 Transposase BCN_3831 ENOG4107TB6 phosphoglycerate mutase BCN_3834 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCN_3836 ENOG4105EKQ RNA-directed DNA polymerase BCN_3842 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCN_3846 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCN_3848 ENOG4105CNI cell division protein FtsW BCN_3851 ENOG4108IAB Phoh family BCN_3855 ENOG4105QA2 BCN_3856 ENOG4105CI3 gtp-binding protein typa BCN_3858 ENOG4105ECY inositol monophosphatase BCN_3862 ENOG4105CXN decarboxylase BCN_3872 ENOG4105CPP Dehydrogenase, E1 component BCN_3875 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCN_3876 ENOG4108X4Q Hydrolase BCN_3878 ENOG4105CN5 Metallo-Beta-Lactamase BCN_3879 ENOG4107ZYR domain protein BCN_3886 ENOG4108XRC Protein of unknown function (DUF458) BCN_3888 ENOG4107IN1 Protein of unknown function (DUF1797) BCN_3892 ENOG4105EPM Diguanylate phosphodiesterase BCN_3893 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCN_3896 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCN_3898 ENOG4105UIN BCN_3904 ENOG4105D7V transposase BCN_3912 ENOG4108HGU Histidine kinase BCN_3914 ENOG4105CHM Aminotransferase BCN_3915 ENOG4105FKQ transcriptional regulator BCN_3916 ENOG4105EG2 ABC transporter, permease BCN_3918 ENOG4107FKK extracellular solute-binding protein family 1 BCN_3920 ENOG4105CG3 alpha amylase, catalytic region BCN_3929 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BCN_3930 ENOG4105CHU acetyl-coa acetyltransferase BCN_3937 ENOG4105K7K Transcriptional regulator BCN_3938 ENOG4105DTD Dehydrogenase BCN_3944 ENOG4105EKQ RNA-directed DNA polymerase BCN_3946 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCN_3954 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCN_3956 ENOG4106TD9 Diguanylate cyclase BCN_3960 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCN_3963 ENOG4105CID antiterminator BCN_3965 ENOG4105FDP GntR family transcriptional regulator BCN_3967 ENOG4105CE4 GlcNAc 6-P deacetylase BCN_3974 ENOG4107ZE5 PPIases accelerate the folding of proteins BCN_3975 ENOG4105PTM secreted protein BCN_3976 ENOG4105J7I hydrolase BCN_3978 ENOG4105G6R Stage v sporulation protein ae BCN_3980 ENOG4105CZ3 stage V sporulation protein ad BCN_3981 ENOG41090VF Stage v sporulation protein ac BCN_3985 ENOG4105C8J )-transporter BCN_3986 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_3988 ENOG41082AN stage II sporulation protein BCN_3989 ENOG4105DZ1 carboxypeptidase BCN_3990 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCN_3991 ENOG4105DVE abc transporter atp-binding protein BCN_3998 ENOG4105DQ6 Transposase BCN_4000 ENOG4105D7N magnesium and cobalt transport protein CorA BCN_4005 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCN_4007 ENOG4105I3K Ferric uptake regulator, Fur family BCN_4008 ENOG4105MZ9 stage II sporulation protein m BCN_4012 ENOG4105CPC Aldo Keto reductase BCN_4014 ENOG4105RHY Pfam:UPF0157 BCN_4018 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCN_4020 ENOG4105ETE Transcriptional regulator (LacI family BCN_4021 ENOG4108YM7 Gcn5-related n-acetyltransferase BCN_4025 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCN_4026 ENOG4108R6K riboflavin synthase, subunit alpha BCN_4031 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCN_4032 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCN_4035 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCN_4038 ENOG4105DFD Na H antiporter BCN_4039 ENOG4105CGH 5'-nucleotidase BCN_4050 ENOG4108IXY short-chain dehydrogenase reductase BCN_4051 ENOG41069FQ Metallo-beta-lactamase superfamily BCN_4052 ENOG4105II7 pyrroline-5-carboxylate reductase BCN_4053 ENOG4105EJQ L-serine dehydratase BCN_4057 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCN_4059 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCN_4060 ENOG4105D9U N-acetyltransferase BCN_4063 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCN_4064 ENOG4108QEG Membrane BCN_4065 ENOG4105CDA abc transporter atp-binding protein BCN_4066 ENOG4105E5Q amino acid AbC transporter BCN_4067 ENOG4108HW3 (ABC) transporter BCN_4070 ENOG4108QY0 Membrane BCN_4073 ENOG4105C7S Dehydrogenase BCN_4074 ENOG4105CPP Dehydrogenase, E1 component BCN_4078 ENOG4107RDP Dehydrogenase BCN_4081 ENOG4108JUB Transcriptional regulator BCN_4083 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCN_4085 ENOG4107QQR Sporulation BCN_4086 ENOG4105S1Z Stage IV sporulation protein B BCN_4087 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCN_4089 ENOG4105DX0 Hemolysin A BCN_4091 ENOG4105CTB Polyprenyl synthetase BCN_4096 ENOG4108ZSR alkaline shock protein BCN_4097 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCN_4102 ENOG410644B Stage III sporulation protein af BCN_4104 ENOG4105KQ4 Stage iii sporulation protein ad BCN_4105 ENOG4108CQH stage III sporulation protein AC BCN_4106 ENOG4105KR5 Stage iii sporulation protein BCN_4107 ENOG4105CD2 stage iii sporulation protein aa BCN_4112 ENOG4105DC7 peptidase M24 BCN_4115 ENOG4105CBJ Metal-dependent enzyme BCN_4122 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BCN_4123 ENOG4105WZW rhodanese family BCN_4127 ENOG41080TC multidrug resistance protein BCN_4134 ENOG4105CJ1 ABC, transporter BCN_4135 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCN_4141 ENOG4105C0D helicase BCN_4166 ENOG4105C3R Methionine synthase BCN_4168 ENOG4105C28 cystathionine BCN_4169 ENOG4105C28 cystathionine BCN_4174 ENOG4105C5X domain protein BCN_4176 ENOG4105DKQ ROK family BCN_4178 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCN_4181 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCN_4182 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCN_4183 ENOG4105E2Z phosphate ABC transporter (Permease BCN_4184 ENOG4105C8U phosphate abc transporter BCN_4185 ENOG4105PWN phosphate abc transporter BCN_4186 ENOG4107RF6 penicillin-binding protein BCN_4188 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCN_4192 ENOG4105N80 Ferric uptake regulator, Fur family BCN_4194 ENOG4105FDK ABC transporter BCN_4195 ENOG4108JYZ YitT family BCN_4196 ENOG41069ZM Protein of unknown function (DUF2624) BCN_4201 ENOG4105EGD dinuclear metal center protein, YbgI family BCN_4204 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_4205 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCN_4211 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCN_4212 ENOG4105KG3 cytidine deaminase BCN_4213 ENOG4107YR5 Diacylglycerol kinase BCN_4215 ENOG4105CTJ Metal Dependent Phosphohydrolase BCN_4216 ENOG4105C9A Phoh family BCN_4219 ENOG41068P3 sporulation protein YqfC BCN_4220 ENOG4105KTH gatB Yqey BCN_4222 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCN_4223 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCN_4230 ENOG4105CSA Coproporphyrinogen iii oxidase BCN_4231 ENOG4105KVH Transcriptional regulator BCN_4236 ENOG4105TQK DNA polymerase iii, delta' subunit BCN_4238 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCN_4239 ENOG4108UK2 deaminase BCN_4240 ENOG4105KQC Competence protein BCN_4242 ENOG4105DXX methyltransferase BCN_4244 ENOG4108WF2 Metal Dependent Phosphohydrolase BCN_4246 ENOG410812S Rna-binding protein BCN_4248 ENOG4105CQW ribosome biogenesis GTPase YqeH BCN_4249 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCN_4252 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_4258 ENOG4105G6Z alkaline phosphatase BCN_4259 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BCN_4260 ENOG4108MUZ hydrolase BCN_4267 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCN_4268 ENOG4105MIR Phenylalanine 4-monooxygenase BCN_4270 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_4278 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCN_4279 ENOG4108HUF Transporter BCN_4281 ENOG4108EKI Dehydrogenase BCN_4282 ENOG4105C28 cystathionine BCN_4288 ENOG4107XRG penicillin-binding protein BCN_4291 ENOG4105CFP Peptidase U32 BCN_4292 ENOG4105XYU peptidase (U32 family) BCN_4293 ENOG4108VQJ O-methyltransferase BCN_4294 ENOG4105HHA aminodeoxychorismate lyase BCN_4300 ENOG4105C02 permease BCN_4303 ENOG41060CR BCN_4304 ENOG4105C7H Helicase, RecD TraA family BCN_4307 ENOG4105C3J Cysteine desulfurase BCN_4309 ENOG4105D1H recombination factor protein RarA BCN_4310 ENOG4108VCI transcription factor, rsfa family BCN_4311 ENOG4105CUZ uba thif-type nad fad binding protein BCN_4317 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCN_4319 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCN_4320 ENOG41076HS cation diffusion facilitator family transporter BCN_4321 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCN_4323 ENOG4105CKP Polysaccharide Biosynthesis Protein BCN_4324 ENOG4108QG2 Membrane BCN_4326 ENOG4105VIE preprotein translocase, subunit YajC BCN_4330 ENOG41061AI Protein of unknown function (DUF2905) BCN_4338 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCN_4339 ENOG4108IYU L-aspartate oxidase BCN_4342 ENOG4108RPX mosc domain containing protein BCN_4343 ENOG4105CQC Prephenate dehydratase BCN_4347 ENOG4105EWM Histidine kinase BCN_4352 ENOG4105X36 (ribosomal) protein BCN_4354 ENOG4105C03 ribonuclease BCN_4357 ENOG4107QMS site-determining protein BCN_4360 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCN_4361 ENOG4105DFF Rod shape-determining protein mreb BCN_4365 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCN_4370 ENOG41068KH stage VI sporulation protein D BCN_4372 ENOG4105D52 delta-aminolevulinic acid dehydratase BCN_4377 ENOG4105K56 Transcriptional regulator BCN_4381 ENOG4108IUQ atp-dependent protease BCN_4387 ENOG4108QCI YvbH-like oligomerisation region BCN_4392 ENOG4105M59 Phosphodiesterase, mj0936 family BCN_4393 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BCN_4395 ENOG4108XJQ germination protein BCN_4397 ENOG4108PCX Major Facilitator BCN_4399 ENOG4105KBX Transcriptional regulator, TetR family BCN_4402 ENOG4105PFC Transcriptional regulator BCN_4405 ENOG4105DZC cytosine deaminase BCN_4406 ENOG41067S9 phage shock protein C, PspC BCN_4407 ENOG4108JCI Transcriptional regulator BCN_4410 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCN_4411 ENOG4108Z40 Transcriptional regulator BCN_4412 ENOG4105RHA ABC transporter, permease BCN_4413 ENOG4108IUX (ABC) transporter BCN_4414 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCN_4415 ENOG4105ER2 Ompa motb domain protein BCN_4416 ENOG4105E14 MotA TolQ exbB proton channel BCN_4417 ENOG4108VXD carboxy-peptidase BCN_4419 ENOG4105E33 succinate dehydrogenase BCN_4421 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCN_4424 ENOG4105K63 Thioredoxin BCN_4425 ENOG4105C10 Electron transfer flavoprotein BCN_4426 ENOG4105BZJ Electron transfer flavoprotein BCN_4427 ENOG41060WC Enoyl-CoA hydratase BCN_4428 ENOG4107Z3H Transcriptional regulator, TetR family BCN_4429 ENOG4105CEY Amp-dependent synthetase and ligase BCN_4438 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCN_4441 ENOG4105DR4 Methyltransferase BCN_4444 ENOG4105KFN sortase, SrtB family BCN_4445 ENOG4105E0A ABC, transporter BCN_4448 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCN_4449 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCN_4451 ENOG4105FE9 pseudouridine synthase BCN_4454 ENOG4105DCG PHP domain protein BCN_4464 ENOG4108RWN rrna methyltransferase BCN_4468 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_4469 ENOG4105CW7 secretion protein, HlyD family BCN_4470 ENOG4108JGH Tetr family transcriptional regulator BCN_4471 ENOG4105CN9 Peptidase m42 family protein BCN_4475 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCN_4476 ENOG4105C22 threonyL-tRNA synthetase BCN_4477 ENOG4108TDW sporulation protein YtxC BCN_4481 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCN_4483 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCN_4484 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BCN_4487 ENOG4105C2M dna polymerase I BCN_4488 ENOG4105BZU Histidine kinase BCN_4489 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCN_4494 ENOG4108HMX isocitrate dehydrogenase (NADP) BCN_4495 ENOG4105BZN citrate synthase BCN_4498 ENOG4108REF Sporulation integral membrane protein ytvi BCN_4499 ENOG4105FS0 cytoplasmic membrane protein BCN_4504 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCN_4505 ENOG4105C6K Malic enzyme BCN_4506 ENOG4105C0B DNA polymerase III (alpha subunit) BCN_4507 ENOG4105VV2 BCN_4509 ENOG4105SFS phosphoesterase RecJ domain protein BCN_4517 ENOG4105DC7 peptidase M24 BCN_4524 ENOG4105Z7P Acetyltransferase (GNAT) family BCN_4525 ENOG41082W1 Cupin 2, conserved barrel domain protein BCN_4528 ENOG4107YZX Universal stress protein BCN_4541 ENOG4108JYZ YitT family BCN_4548 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCN_4549 ENOG4105KBJ sporulation protein ytfj BCN_4552 ENOG4105EFZ amidohydrolase BCN_4554 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCN_4559 ENOG4105C5Q Transcriptional regulator BCN_4561 ENOG4105U5Y Transcriptional regulator BCN_4563 ENOG4105C28 cystathionine BCN_4570 ENOG4105EMN RNA polymerase sigma factor BCN_4573 ENOG4105F1V Acetoin utilization protein BCN_4574 ENOG4105W87 Cbs domain BCN_4575 ENOG4105DGU Histone deacetylase BCN_4578 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCN_4580 ENOG4105EP9 oxidoreductase BCN_4586 ENOG4105ETE Transcriptional regulator (LacI family BCN_4591 ENOG4105C88 aminopeptidase BCN_4601 ENOG4108VDD TRNA binding domain protein BCN_4607 ENOG4105C8F Beta-lactamase domain protein BCN_4610 ENOG4108V15 phosphotransferase enzyme family BCN_4611 ENOG4108IUM Glycogen debranching enzyme BCN_4613 ENOG4107QSE Dipeptidase BCN_4614 ENOG4105YW5 deoR family transcriptional regulator BCN_4617 ENOG4105CBX hi0933 family BCN_4624 ENOG4108VJ1 Transcriptional regulator (CarD family BCN_4625 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCN_4629 ENOG4108ZAF Molybdopterin BCN_4630 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCN_4631 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCN_4633 ENOG4105D06 uba thif-type nad fad binding protein BCN_4634 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCN_4638 ENOG41085GJ domain protein BCN_4640 ENOG4105DWV Homoserine O-trans-acetylase BCN_4642 ENOG4108B31 Spore germination protein BCN_4648 ENOG410605W Major Facilitator BCN_4649 ENOG4107S91 Sodium hydrogen exchanger BCN_4650 ENOG4105NCW Trka-c domain protein BCN_4653 ENOG4105C19 ABC transporter BCN_4658 ENOG4105N5T Radical SAM Protein BCN_4660 ENOG4105CIG ABC transporter BCN_4667 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCN_4668 ENOG4108Z0R Transferase BCN_4669 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCN_4670 ENOG4105BZF Glycosyl transferase (Group 1 BCN_4672 ENOG4108RIR Molybdenum cofactor biosynthesis protein BCN_4675 ENOG4108MK9 spermidine N(1)-acetyltransferase BCN_4688 ENOG4105BZU Histidine kinase BCN_4689 ENOG4105BZU Histidine kinase BCN_4690 ENOG4107S9D Alpha beta hydrolase BCN_4691 ENOG4107T7U Sulfatase BCN_4695 ENOG4105D2X ABC transporter substrate-binding protein BCN_4697 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCN_4708 ENOG4108V2W Carbonate dehydratase BCN_4709 ENOG4105C4M (Ubiquinol oxidase) subunit I BCN_4710 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCN_4720 ENOG41087YS Phage shock protein A BCN_4727 ENOG4105BZU Histidine kinase BCN_4728 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_4734 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCN_4735 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCN_4740 ENOG4105C19 ABC transporter BCN_4743 ENOG4107ZTW SNARE associated Golgi BCN_4749 ENOG4105C19 ABC transporter BCN_4750 ENOG41086D8 Transcriptional regulator BCN_4752 ENOG41082BM Transcriptional regulator, arsr family BCN_4760 ENOG4105C6Z Gluconate BCN_4761 ENOG4105FDP GntR family transcriptional regulator BCN_4765 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCN_4769 ENOG4105DTQ mandelate racemase muconate lactonizing BCN_4771 ENOG4108IPT Naphthoate synthase BCN_4772 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCN_4774 ENOG4105E4F Isochorismate synthase BCN_4775 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCN_4777 ENOG4105VEQ Cold shock protein BCN_4788 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCN_4791 ENOG4105KT7 mgtC SapB transporter BCN_4792 ENOG4107PBV potassium channel BCN_4795 ENOG4105WG9 Conserved Protein BCN_4797 ENOG4105CHM Aminotransferase BCN_4798 ENOG4108ZB6 transcriptional regulator AsnC family BCN_4799 ENOG4105C5I Dehydrogenase BCN_4800 ENOG4108MUZ hydrolase BCN_4802 ENOG4105C87 Aminotransferase class I and II BCN_4805 ENOG4105Y38 Kinase-associated protein B BCN_4807 ENOG4107R3E Citrate transporter BCN_4811 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCN_4812 ENOG4105KA0 thioesterase Superfamily protein BCN_4816 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCN_4820 ENOG41069ER domain protein BCN_4823 ENOG4105CEP NADH dehydrogenase BCN_4828 ENOG4105EWC Purine nucleoside phosphorylase BCN_4832 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCN_4837 ENOG4108JJA ABC, transporter BCN_4838 ENOG4105C4B ABC transporter, permease BCN_4839 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCN_4848 ENOG41083MR nifu domain-containing protein BCN_4851 ENOG4108W5N phosphatidylglycerophosphatase a BCN_4853 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCN_4854 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCN_4857 ENOG4105CBT Fructose-1,6-bisphosphatase BCN_4861 ENOG4105MMD transcriptional regulator BCN_4862 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCN_4863 ENOG4107TXC Transcriptional regulator BCN_4864 ENOG41090T1 Membrane BCN_4869 ENOG4105FAA peptidase M23 BCN_4871 ENOG4105KZD Domain of unknown function (DUF1805) BCN_4872 ENOG4107R8B 5'-nucleotidase BCN_4874 ENOG4105DIW FeS assembly protein SUFB BCN_4875 ENOG4108UNV SUF system FeS assembly protein, NifU family BCN_4876 ENOG4105C9B Cysteine desulfurase BCN_4877 ENOG4105JRK feS assembly protein SufD BCN_4878 ENOG4105C3K feS assembly ATPase SufC BCN_4879 ENOG4105D01 (LipO)protein BCN_4880 ENOG4105D01 (LipO)protein BCN_4881 ENOG4108UMI ABC transporter, permease BCN_4887 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCN_4902 ENOG4108W8B Beta-lactamase domain protein BCN_4903 ENOG4105C1G acyl-Coa dehydrogenase BCN_4904 ENOG4105CHU acetyl-coa acetyltransferase BCN_4908 ENOG4105DZ1 carboxypeptidase BCN_4912 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCN_4913 ENOG4105D7V transposase BCN_4917 ENOG4105F27 Major Facilitator BCN_4918 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BCN_4920 ENOG4107R7I amino acid BCN_4926 ENOG4105DQ6 Transposase BCN_4927 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCN_4930 ENOG4107AYK membrAne BCN_4937 ENOG4107ZTW SNARE associated Golgi BCN_4939 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCN_4940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_4941 ENOG4105BZU Histidine kinase BCN_4946 ENOG4105C8Q Methyl-accepting chemotaxis BCN_4947 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCN_4948 ENOG4105VG1 fes assembly suf system protein BCN_4949 ENOG4105D4Y metalloprotease BCN_4953 ENOG4107S91 Sodium hydrogen exchanger BCN_4954 ENOG4105NCW Trka-c domain protein BCN_4959 ENOG4108RMU ferritin dps family protein BCN_4963 ENOG4108URH decarboxylase BCN_4967 ENOG4105D9N nucleoside BCN_4970 ENOG4108RYK Nad-dependent epimerase dehydratase BCN_4972 ENOG4105DQ6 Transposase BCN_4976 ENOG4105CV8 reductase BCN_4977 ENOG4105F27 Major Facilitator BCN_4978 ENOG4105KVH Transcriptional regulator BCN_4982 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCN_4983 ENOG4105D4A Cell wall formation (By similarity) BCN_4988 ENOG4105C8Q Methyl-accepting chemotaxis BCN_4990 ENOG4105WMR Protein CrcB homolog BCN_4995 ENOG4105C5H ABC transporter BCN_4996 ENOG4108MK9 spermidine N(1)-acetyltransferase BCN_4997 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BCN_4999 ENOG4108IPW abc transporter atp-binding protein BCN_5000 ENOG4105CM4 permease protein BCN_5006 ENOG4105C19 ABC transporter BCN_5010 ENOG4107ZTW SNARE associated Golgi BCN_5016 ENOG41086D8 Transcriptional regulator BCN_5019 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BCN_5020 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCN_5022 ENOG4108ZHR arsR family transcriptional regulator BCN_5023 ENOG4105DHF Membrane BCN_5027 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCN_5029 ENOG4105XZU Preprotein translocase, subunit SecG BCN_5030 ENOG41067MG lrgb family BCN_5040 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_5050 ENOG4107QMH DNA methylase BCN_5055 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCN_5058 ENOG41090VF Stage v sporulation protein ac BCN_5059 ENOG4105CZ3 stage V sporulation protein ad BCN_5062 ENOG4108QY0 Membrane BCN_5063 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCN_5064 ENOG4105KRI phosphocarrier protein (HPr BCN_5066 ENOG4105CHW UPF0052 protein BCN_5068 ENOG4108Z4K mutator MutT protein BCN_5070 ENOG4105C3M thioredoxin reductase BCN_5072 ENOG4108S4C acetyltransferase BCN_5076 ENOG41086DT Membrane protein of unknown function BCN_5079 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCN_5083 ENOG4107TXC Transcriptional regulator BCN_5090 ENOG4105DUM transcriptional regulator, lysR family BCN_5092 ENOG4108WS4 fmn reductase BCN_5093 ENOG4105C5H ABC transporter BCN_5095 ENOG4105BZ1 (ABC) transporter BCN_5097 ENOG4105CN1 protease BCN_5098 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCN_5099 ENOG4105CAK Cell division ATP-binding protein ftsE BCN_5102 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BCN_5105 ENOG4105MS2 ribosomal subunit Interface protein BCN_5107 ENOG4105VEQ Cold shock protein BCN_5108 ENOG41081UC Inherit from COG: Competence protein BCN_5110 ENOG4105K4H Nlp p60 protein BCN_5111 ENOG4105KVH Transcriptional regulator BCN_5114 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCN_5115 ENOG4108KGH TRANSCRIPTIONal BCN_5116 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCN_5117 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCN_5118 ENOG4105ESV Glycosyl transferase, family 4 BCN_5120 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCN_5124 ENOG4105F8D glycoside hydrolase family 4 BCN_5125 ENOG4105VCP PTS System BCN_5126 ENOG4105CK1 PTS System BCN_5128 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BCN_5132 ENOG4105VCP PTS System BCN_5134 ENOG4105VZJ PTS System BCN_5137 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BCN_5141 ENOG4105ECB domain protein BCN_5142 ENOG4105ECB domain protein BCN_5143 ENOG4107RSM transcriptional regulator BCN_5150 ENOG4105DAA L-lactate BCN_5152 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCN_5154 ENOG4105E0M Sulfatase BCN_5160 ENOG4107R8N Glycosyl transferase, family 2 BCN_5163 ENOG4105C94 Transporter BCN_5164 ENOG41069ER domain protein BCN_5169 ENOG4105KBK Zinc finger, swim domain protein BCN_5170 ENOG4105C0D helicase BCN_5176 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCN_5178 ENOG4107RBB ABC transporter, permease BCN_5179 ENOG4105C19 ABC transporter BCN_5181 ENOG4105CXY transporter BCN_5184 ENOG41062D9 Histidine kinase BCN_5185 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_5186 ENOG4105CMR udp-glucose 4-epimerase BCN_5188 ENOG4108KGH TRANSCRIPTIONal BCN_5189 ENOG4105CMR udp-glucose 4-epimerase BCN_5192 ENOG4105CG5 Glycosyl transferase (Group 1 BCN_5196 ENOG4105C5E polysaccharide biosynthesis protein BCN_5198 ENOG4105CMR udp-glucose 4-epimerase BCN_5199 ENOG4105D3Q Sugar transferase BCN_5201 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCN_5202 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BCN_5203 ENOG4107YJ4 chain length determinant protein BCN_5204 ENOG4105HTX biosynthesis protein BCN_5205 ENOG4108QV3 biosynthesis protein BCN_5208 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCN_5210 ENOG4105FRN stage II sporulation protein BCN_5213 ENOG4105DY9 regulatoR BCN_5217 ENOG4106778 Protein of unknown function (DUF1146) BCN_5218 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCN_5219 ENOG4105C8S subunit m BCN_5220 ENOG4105D65 subunit l BCN_5226 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCN_5228 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCN_5229 ENOG4105BZU Histidine kinase BCN_5240 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCN_5241 ENOG41062M3 atp synthase BCN_5248 ENOG4108YZG isomerase BCN_5251 ENOG4108VGI doxx family BCN_5252 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCN_5255 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCN_5257 ENOG4108ZXQ stage ii sporulation protein r BCN_5258 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCN_5259 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCN_5262 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCN_5263 ENOG4105CBT Fructose-1,6-bisphosphatase BCN_5264 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCN_5271 ENOG4105C1G acyl-Coa dehydrogenase BCN_5272 ENOG4105C1G acyl-Coa dehydrogenase BCN_5273 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCN_5275 ENOG4105DF6 Fe-S oxidoreductase BCN_5278 ENOG4105BZU Histidine kinase BCN_5282 ENOG4105BZU Histidine kinase BCN_5283 ENOG4105KCT ABC transporter BCN_5284 ENOG4108M15 ABC transporter BCN_5285 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCN_5287 ENOG4105IIU Aminopeptidase BCN_5291 ENOG4105EMN RNA polymerase sigma factor BCN_5293 ENOG410684U Domain of unknown function (DUF1934) BCN_5297 ENOG4105CYW agmatinase BCN_5299 ENOG4105DXB Major Facilitator superfamily BCN_5300 ENOG4107SWG transcriptional regulator MERR family BCN_5301 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCN_5302 ENOG4105BZ4 penicillin-binding protein BCN_5303 ENOG4108XFG YwhD family BCN_5304 ENOG4108Z4T Peptidase M50 BCN_5305 ENOG41069HH 4-oxalocrotonate tautomerase BCN_5306 ENOG4105DCI Phosphohydrolase BCN_5307 ENOG4108MES Periplasmic binding protein BCN_5308 ENOG4105E0A ABC, transporter BCN_5309 ENOG4105EHG Permease protein BCN_5310 ENOG4105DQ5 transport system permease protein BCN_5312 ENOG4108VCI transcription factor, rsfa family BCN_5315 ENOG4108IJ2 phosphate acetyltransferase BCN_5318 ENOG4108VKI Cell wall hydrolase BCN_5322 ENOG4107SVH Potassium channel protein BCN_5324 ENOG410667J hydrolase BCN_5325 ENOG4105VCH membrane BCN_5327 ENOG4108TU7 Inherit from COG: (ABC) transporter BCN_5328 ENOG4105CJ1 ABC, transporter BCN_5329 ENOG41090WU lipolytic protein G-D-S-L family BCN_5332 ENOG4105D6E homoserine dehydrogenase BCN_5337 ENOG4108Y4K DNA-binding transcriptional activator BCN_5339 ENOG4105WH1 Two component transcriptional regulator luxr family BCN_5340 ENOG4105BZU Histidine kinase BCN_5341 ENOG4105DWF phosphomethylpyrimidine kinase BCN_5342 ENOG4105BZU Histidine kinase BCN_5343 ENOG4105VCD cytoplasmic protein BCN_5344 ENOG4105D22 carbon starvation protein BCN_5345 ENOG4105DY9 regulatoR BCN_5346 ENOG41079KZ Major Facilitator Superfamily BCN_5348 ENOG4105CG5 Glycosyl transferase (Group 1 BCN_5350 ENOG4105EN6 Membrane BCN_5351 ENOG4106YBV Methyl-accepting chemotaxis BCN_5353 ENOG4108S4H thioesterase Superfamily protein BCN_5354 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BCN_5357 ENOG4105K64 Glycosyl transferase, family 2 BCN_5359 ENOG4105C5H ABC transporter BCN_5360 ENOG41067SE Tetr family transcriptional regulator BCN_5362 ENOG4105E0X reductase BCN_5363 ENOG4106F5Q Membrane BCN_5366 ENOG4105DY9 regulatoR BCN_5367 ENOG4108HRK Histidine kinase BCN_5368 ENOG4107RGD Major Facilitator superfamily BCN_5371 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCN_5373 ENOG4105IW1 AmiS UreI transporter BCN_5379 ENOG4105CMR udp-glucose 4-epimerase BCN_5380 ENOG4108UT2 hemolysin iii BCN_5382 ENOG4105C1J atp-dependent rna helicase BCN_5384 ENOG4105DPN Oligoendopeptidase f BCN_5388 ENOG4105C0H protease BCN_5389 ENOG4105Q2H domain protein BCN_5392 ENOG4105BZU Histidine kinase BCN_5393 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_5395 ENOG4105CDU Replicative dna helicase BCN_5397 ENOG4105BZR domain protein BCN_5398 ENOG4108XMW Membrane BCN_5400 ENOG4108UUM single-stranded DNA-binding protein BCN_5402 ENOG4105C3G gtp-binding protein BCN_5403 ENOG4105VDK protein, conserved in bacteria BCN_5404 ENOG4105D8X mechanosensitive ion channel BCN_5405 ENOG4108ZDA Sporulation protein YyaC BCN_5406 ENOG4105FA0 parb-like partition protein BCN_5407 ENOG4107QJE Chromosome Partitioning Protein BCN_5413 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCN_C1_05 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCN_C1_24 ENOG4108TFU terminase (Small subunit) BCN_C1_38 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BCN_C2_06 ENOG4105VN1 Heat shock protein BCN_C2_08 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BCN_P011 ENOG4105EKQ RNA-directed DNA polymerase BCN_P015 ENOG4105CIG ABC transporter BCN_P027 ENOG4108M1A Chitin-binding protein BCN_P032 ENOG4107SDU Methyl-accepting chemotaxis BCN_P036 ENOG4105K4H Nlp p60 protein BCN_P038 ENOG41080HT Transcriptional regulator, arsr family BCN_P064 ENOG4105EKQ RNA-directed DNA polymerase BCN_P076 ENOG4105EKQ RNA-directed DNA polymerase BCN_P077 ENOG4107QZI cell division protein FtsK BCN_P083 ENOG4105D7V transposase BCN_P092 ENOG4105DQ6 Transposase BCN_P093 ENOG4105IYK transposase BCN_P103 ENOG4105D7V transposase BCN_P133 ENOG41067XF inhibitor BCN_P146 ENOG4105EKQ RNA-directed DNA polymerase BCN_P158 ENOG4105DHF Membrane BCN_P162 ENOG4105K70 DNA-binding protein BCN_P165 ENOG4105KRN Transcriptional regulator, abrb family BCN_P168 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCN_P175 ENOG4108IBT Inherit from COG: transposase BCN_P186 ENOG41086D8 Transcriptional regulator BCN_P191 ENOG4105K59 histidine triad (HIT) protein BCN_P200 ENOG4105VMP Transcriptional regulator BCN_P204 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCN_P206 ENOG4105H67 Protein of unknown function (DUF421) BCN_P211 ENOG41090VF Stage v sporulation protein ac BCN_P212 ENOG4105CZ3 stage V sporulation protein ad BCN_P215 ENOG4108QY0 Membrane BCN_P216 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCN_P220 ENOG4108B31 Spore germination protein BCN_P221 ENOG4105E1K spore germination protein BCN_P225 ENOG4105KVH Transcriptional regulator BCN_P227 ENOG4105C4W S-formylglutathione hydrolase BCN_P230 ENOG4105D9M gamma-glutamylcysteine synthetase BCN_P234 ENOG4108NHD germination protein BCN_P238 ENOG4108W2Y isochorismatase BCN_P241 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCN_P242 ENOG4105BZU Histidine kinase BCN_P253 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)