locus-tag class description ACN91_00010 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) ACN91_00020 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ACN91_00025 ENOG4105KRF dihydroneopterin aldolase ACN91_00030 ENOG4105EEI dihydropteroate synthase ACN91_00035 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 ACN91_00040 ENOG4105DDQ anthranilate synthase ACN91_00045 ENOG4105CRQ synthase (Component I) ACN91_00050 ENOG4105C6T cysteine synthase ACN91_00065 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) ACN91_00070 ENOG4108UGV hypoxanthine phosphoribosyltransferase ACN91_00075 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) ACN91_00095 ENOG41060GV RNA binding s1 domain protein ACN91_00110 ENOG4105VYY sporulation protein yabp ACN91_00115 ENOG41082I2 s4 domain protein ACN91_00120 ENOG4108IY2 MazG family ACN91_00130 ENOG4108M14 stage v sporulation protein t ACN91_00135 ENOG4108JA2 transcriptioN-repair coupling factor ACN91_00145 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) ACN91_00150 ENOG4105C5T Phosphoribosyl pyrophosphate synthase ACN91_00165 ENOG4105KME endoribonuclease L-psp ACN91_00170 ENOG4105DFT pur operon repressor ACN91_00185 ENOG4105W42 Veg protein ACN91_00190 ENOG4105XFA sporulation peptidase YabG ACN91_00200 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) ACN91_00205 ENOG4105F8V Hydrolase, tatD family ACN91_00210 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) ACN91_00215 ENOG4105KRN Transcriptional regulator, abrb family ACN91_00220 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) ACN91_00230 ENOG41060K3 Methyltransferase ACN91_00240 ENOG4105MA4 psp1 domain protein ACN91_00245 ENOG4105FA2 dna polymerase iii ACN91_00255 ENOG4105CXN decarboxylase ACN91_00290 ENOG41067KS pro-sigma K processing ACN91_00310 ENOG4105C6E dna polymerase iii ACN91_00315 ENOG4108Z6B deaminase ACN91_00325 ENOG4105GTG Isochorismatase ACN91_00335 ENOG4105ZMH deoxynucleoside kinase ACN91_00370 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) ACN91_00405 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ACN91_00420 ENOG410848D S4 domain protein YaaA ACN91_00425 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ACN91_00445 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ACN91_00455 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) ACN91_00460 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) ACN91_00475 ENOG4107QJE Chromosome Partitioning Protein ACN91_00480 ENOG4105FA0 parb-like partition protein ACN91_00485 ENOG4108ZDA Sporulation protein YyaC ACN91_00490 ENOG4105D8X mechanosensitive ion channel ACN91_00495 ENOG4105VDK protein, conserved in bacteria ACN91_00500 ENOG4105C3G gtp-binding protein ACN91_00510 ENOG4108UUM single-stranded DNA-binding protein ACN91_00520 ENOG4108XMW Membrane ACN91_00525 ENOG4105BZR domain protein ACN91_00535 ENOG4105CDU Replicative dna helicase ACN91_00540 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis ACN91_00565 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_00570 ENOG4105BZU Histidine kinase ACN91_00585 ENOG4105Q2H domain protein ACN91_00590 ENOG4105C0H protease ACN91_00605 ENOG4105BZU Histidine kinase ACN91_00615 ENOG4105DPN Oligoendopeptidase f ACN91_00620 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) ACN91_00625 ENOG4105C1J atp-dependent rna helicase ACN91_00640 ENOG4108UT2 hemolysin iii ACN91_00645 ENOG4105CMR udp-glucose 4-epimerase ACN91_00650 ENOG4105IW1 AmiS UreI transporter ACN91_00660 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ACN91_00675 ENOG4107RGD Major Facilitator superfamily ACN91_00680 ENOG4108HRK Histidine kinase ACN91_00685 ENOG4108NEV two component transcriptional regulator, LytTR family ACN91_00700 ENOG4106F5Q Membrane ACN91_00705 ENOG4105E0X reductase ACN91_00715 ENOG41067SE Tetr family transcriptional regulator ACN91_00720 ENOG4105CKK Glycosyl transferase, family 2 ACN91_00735 ENOG4105C5H ABC transporter ACN91_00745 ENOG4105K64 Glycosyl transferase, family 2 ACN91_00755 ENOG4108S4H thioesterase Superfamily protein ACN91_00765 ENOG4106YBV Methyl-accepting chemotaxis ACN91_00770 ENOG4105EN6 Membrane ACN91_00780 ENOG4105CG5 Glycosyl transferase (Group 1 ACN91_00790 ENOG41079KZ Major Facilitator Superfamily ACN91_00795 ENOG4105DY9 regulatoR ACN91_00800 ENOG4105D22 carbon starvation protein ACN91_00805 ENOG4105VCD cytoplasmic protein ACN91_00810 ENOG4105BZU Histidine kinase ACN91_00815 ENOG4105DWF phosphomethylpyrimidine kinase ACN91_00820 ENOG4105BZU Histidine kinase ACN91_00825 ENOG4105WH1 Two component transcriptional regulator luxr family ACN91_00835 ENOG4108Y4K DNA-binding transcriptional activator ACN91_00855 ENOG4105CVG Homoserine O-transsuccinylase ACN91_00860 ENOG4105D6E homoserine dehydrogenase ACN91_00875 ENOG41090WU lipolytic protein G-D-S-L family ACN91_00880 ENOG4105CJ1 ABC, transporter ACN91_00885 ENOG4108TU7 Inherit from COG: (ABC) transporter ACN91_00895 ENOG4105VCH membrane ACN91_00900 ENOG410667J hydrolase ACN91_00910 ENOG4107SVH Potassium channel protein ACN91_00930 ENOG4108VKI Cell wall hydrolase ACN91_00940 ENOG4107UEZ chlorite dismutase ACN91_00945 ENOG4108IJ2 phosphate acetyltransferase ACN91_00950 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) ACN91_00955 ENOG4108VCI transcription factor, rsfa family ACN91_00965 ENOG4105DQ5 transport system permease protein ACN91_00970 ENOG4105EHG Permease protein ACN91_00975 ENOG4105E0A ABC, transporter ACN91_00980 ENOG4108MES Periplasmic binding protein ACN91_00985 ENOG4105DCI Phosphohydrolase ACN91_00990 ENOG41069HH 4-oxalocrotonate tautomerase ACN91_00995 ENOG4108Z4T Peptidase M50 ACN91_01000 ENOG4108XFG YwhD family ACN91_01005 ENOG4105BZ4 penicillin-binding protein ACN91_01010 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ACN91_01015 ENOG4107SWG transcriptional regulator MERR family ACN91_01020 ENOG4105DXB Major Facilitator superfamily ACN91_01030 ENOG4105CYW agmatinase ACN91_01050 ENOG410684U Domain of unknown function (DUF1934) ACN91_01060 ENOG4105EMN RNA polymerase sigma factor ACN91_01080 ENOG4105IIU Aminopeptidase ACN91_01090 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) ACN91_01095 ENOG4108M15 ABC transporter ACN91_01100 ENOG4105KCT ABC transporter ACN91_01105 ENOG4105BZU Histidine kinase ACN91_01115 ENOG4105D4Y metalloprotease ACN91_01130 ENOG4105BZU Histidine kinase ACN91_01145 ENOG4105DF6 Fe-S oxidoreductase ACN91_01155 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase ACN91_01160 ENOG4105C1G acyl-Coa dehydrogenase ACN91_01165 ENOG4105C1G acyl-Coa dehydrogenase ACN91_01180 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) ACN91_01200 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) ACN91_01205 ENOG4105CBT Fructose-1,6-bisphosphatase ACN91_01210 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) ACN91_01225 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) ACN91_01230 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) ACN91_01235 ENOG4108ZXQ stage ii sporulation protein r ACN91_01245 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ACN91_01265 ENOG4107XC4 flavin reductase domain protein, FMN-binding ACN91_01270 ENOG4108VGI doxx family ACN91_01285 ENOG4108YZG isomerase ACN91_01290 ENOG4108UIC UPF0340 protein ACN91_01295 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) ACN91_01315 ENOG41062M3 atp synthase ACN91_01320 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) ACN91_01370 ENOG4105BZU Histidine kinase ACN91_01375 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain ACN91_01385 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain ACN91_01390 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ACN91_01415 ENOG4105D65 subunit l ACN91_01420 ENOG4105C8S subunit m ACN91_01425 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) ACN91_01430 ENOG4106778 Protein of unknown function (DUF1146) ACN91_01450 ENOG4105DY9 regulatoR ACN91_01465 ENOG4105FRN stage II sporulation protein ACN91_01475 ENOG4105MT0 Sporulation transcriptional regulator spoiiid ACN91_01490 ENOG4107YJ4 chain length determinant protein ACN91_01495 ENOG4105HTX biosynthesis protein ACN91_01500 ENOG4107YJ4 chain length determinant protein ACN91_01505 ENOG4108RB3 Capsular polysaccharide biosynthesis protein ACN91_01510 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ACN91_01520 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase ACN91_01525 ENOG4105CPF Cell wall formation (By similarity) ACN91_01530 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) ACN91_01540 ENOG4107T8Q Glycosyl transferase (Group 1 ACN91_01550 ENOG4105K64 Glycosyl transferase, family 2 ACN91_01560 ENOG4108KGH TRANSCRIPTIONal ACN91_01570 ENOG4105CMR udp-glucose 4-epimerase ACN91_01575 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_01580 ENOG4105BZU Histidine kinase ACN91_01595 ENOG4105CXY transporter ACN91_01605 ENOG4105C19 ABC transporter ACN91_01610 ENOG4107RBB ABC transporter, permease ACN91_01620 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_01655 ENOG4105C0D helicase ACN91_01660 ENOG4105KBK Zinc finger, swim domain protein ACN91_01685 ENOG41069ER domain protein ACN91_01690 ENOG4105C94 Transporter ACN91_01700 ENOG4107R8N Glycosyl transferase, family 2 ACN91_01725 ENOG4105E0M Sulfatase ACN91_01735 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) ACN91_01745 ENOG4105DAA L-lactate ACN91_01800 ENOG4107RSM transcriptional regulator ACN91_01805 ENOG4105ECB domain protein ACN91_01825 ENOG4105VZJ PTS System ACN91_01835 ENOG4105VCP PTS System ACN91_01840 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) ACN91_01845 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) ACN91_01855 ENOG4105CK1 PTS System ACN91_01860 ENOG4105VCP PTS System ACN91_01865 ENOG4105F8D glycoside hydrolase family 4 ACN91_01885 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family ACN91_01895 ENOG4105ESV Glycosyl transferase, family 4 ACN91_01905 ENOG4105C6Y Udp-glucose 6-dehydrogenase ACN91_01910 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase ACN91_01915 ENOG4108KGH TRANSCRIPTIONal ACN91_01920 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein ACN91_01930 ENOG4105KVH Transcriptional regulator ACN91_01945 ENOG41081UC Inherit from COG: Competence protein ACN91_01950 ENOG4105VEQ Cold shock protein ACN91_01955 ENOG4105MS2 ribosomal subunit Interface protein ACN91_01965 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) ACN91_01980 ENOG4105CAK Cell division ATP-binding protein ftsE ACN91_01985 ENOG4105CRP Part of the ABC transporter FtsEX involved in ACN91_01990 ENOG4105CN1 protease ACN91_02000 ENOG4105BZ1 (ABC) transporter ACN91_02010 ENOG4105C5H ABC transporter ACN91_02015 ENOG4108WS4 fmn reductase ACN91_02025 ENOG4105DUM transcriptional regulator, lysR family ACN91_02030 ENOG4105HMI Membrane ACN91_02060 ENOG4107TXC Transcriptional regulator ACN91_02080 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ACN91_02085 ENOG41086DT Membrane protein of unknown function ACN91_02105 ENOG4108S4C acetyltransferase ACN91_02115 ENOG4105C3M thioredoxin reductase ACN91_02125 ENOG4108Z4K mutator MutT protein ACN91_02130 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) ACN91_02135 ENOG4105CHW UPF0052 protein ACN91_02145 ENOG4105KRI phosphocarrier protein (HPr ACN91_02150 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) ACN91_02155 ENOG4108QY0 Membrane ACN91_02170 ENOG4105CZ3 stage V sporulation protein ad ACN91_02175 ENOG41090VF Stage v sporulation protein ac ACN91_02195 ENOG4108W5X Transcriptional Regulator, LuxR family ACN91_02200 ENOG4105BZU Histidine kinase ACN91_02205 ENOG4108IUX (ABC) transporter ACN91_02210 ENOG4105RHA ABC transporter, permease ACN91_02215 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_02265 ENOG41067MG lrgb family ACN91_02270 ENOG4105XZU Preprotein translocase, subunit SecG ACN91_02280 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) ACN91_02305 ENOG4105CM4 permease protein ACN91_02310 ENOG4108IPW abc transporter atp-binding protein ACN91_02345 ENOG4108W2Y isochorismatase ACN91_02355 ENOG4108VY7 phosphate-starvation-inducible protein PsiE ACN91_02360 ENOG4108MK9 spermidine N(1)-acetyltransferase ACN91_02365 ENOG4105C5H ABC transporter ACN91_02385 ENOG4105WMR Protein CrcB homolog ACN91_02390 ENOG4105WMR Protein CrcB homolog ACN91_02410 ENOG4105D4A Cell wall formation (By similarity) ACN91_02415 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) ACN91_02430 ENOG4105KVH Transcriptional regulator ACN91_02435 ENOG4105F27 Major Facilitator ACN91_02440 ENOG4105CV8 reductase ACN91_02455 ENOG4108RYK Nad-dependent epimerase dehydratase ACN91_02470 ENOG4105D9N nucleoside ACN91_02475 ENOG4105D9N nucleoside ACN91_02485 ENOG41090A1 ferritin ACN91_02495 ENOG4108URH decarboxylase ACN91_02515 ENOG4108RMU ferritin dps family protein ACN91_02530 ENOG4105NCW Trka-c domain protein ACN91_02535 ENOG4107S91 Sodium hydrogen exchanger ACN91_02540 ENOG4107T5V SNARE associated Golgi ACN91_02560 ENOG4105D4Y metalloprotease ACN91_02565 ENOG4105VG1 fes assembly suf system protein ACN91_02570 ENOG4105C8Q Methyl-accepting chemotaxis ACN91_02600 ENOG4105BZU Histidine kinase ACN91_02605 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_02610 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ACN91_02620 ENOG4107ZTW SNARE associated Golgi ACN91_02655 ENOG4107AYK membrAne ACN91_02665 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins ACN91_02680 ENOG4107R7I amino acid ACN91_02685 ENOG4108SUT Major Facilitator Superfamily ACN91_02705 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer ACN91_02740 ENOG4105DZ1 carboxypeptidase ACN91_02755 ENOG4105CHU acetyl-coa acetyltransferase ACN91_02760 ENOG4105C1G acyl-Coa dehydrogenase ACN91_02765 ENOG4108W8B Beta-lactamase domain protein ACN91_02790 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) ACN91_02825 ENOG41080E8 Transcriptional regulator, Spx MgsR family ACN91_02850 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ACN91_02855 ENOG4108UMI ABC transporter, permease ACN91_02860 ENOG4105D01 (LipO)protein ACN91_02865 ENOG4105D01 (LipO)protein ACN91_02870 ENOG4105C3K feS assembly ATPase SufC ACN91_02875 ENOG4105JRK feS assembly protein SufD ACN91_02880 ENOG4105C9B Cysteine desulfurase ACN91_02885 ENOG4108UNV SUF system FeS assembly protein, NifU family ACN91_02890 ENOG4105DIW FeS assembly protein SUFB ACN91_02895 ENOG4107R8B 5'-nucleotidase ACN91_02900 ENOG4105KZD Domain of unknown function (DUF1805) ACN91_02905 ENOG4108YTE sporulation protein YunB ACN91_02910 ENOG4105FAA peptidase M23 ACN91_02935 ENOG41090T1 Membrane ACN91_02940 ENOG4107TXC Transcriptional regulator ACN91_02945 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ACN91_02950 ENOG4105MMD transcriptional regulator ACN91_02970 ENOG4105CBT Fructose-1,6-bisphosphatase ACN91_02985 ENOG4105D4U had-superfamily hydrolase, subfamily iia ACN91_02990 ENOG4105DYS nad(p)h dehydrogenase (quinone) ACN91_03000 ENOG4105DAX Pfam:DUF2983 ACN91_03020 ENOG4108W5N phosphatidylglycerophosphatase a ACN91_03035 ENOG41083MR nifu domain-containing protein ACN91_03090 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ACN91_03095 ENOG4105C4B ABC transporter, permease ACN91_03100 ENOG4108JJA ABC, transporter ACN91_03125 ENOG4108YX9 iron--sulfur cluster insertion protein erpA ACN91_03140 ENOG4108VQJ O-methyltransferase ACN91_03150 ENOG4105EWC Purine nucleoside phosphorylase ACN91_03180 ENOG4105CEP NADH dehydrogenase ACN91_03195 ENOG41069ER domain protein ACN91_03215 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase ACN91_03230 ENOG4105KA0 thioesterase Superfamily protein ACN91_03235 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) ACN91_03250 ENOG4107R3E Citrate transporter ACN91_03260 ENOG4105Y38 Kinase-associated protein B ACN91_03275 ENOG4105C87 Aminotransferase class I and II ACN91_03285 ENOG4108MUZ hydrolase ACN91_03290 ENOG4105C5I Dehydrogenase ACN91_03295 ENOG4108ZB6 transcriptional regulator AsnC family ACN91_03300 ENOG4105CHM Aminotransferase ACN91_03310 ENOG4105WG9 Conserved Protein ACN91_03330 ENOG4107PBV potassium channel ACN91_03335 ENOG4105KT7 mgtC SapB transporter ACN91_03480 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin ACN91_03490 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) ACN91_03495 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) ACN91_03540 ENOG4105VEQ Cold shock protein ACN91_03550 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ACN91_03555 ENOG4105E4F Isochorismate synthase ACN91_03560 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) ACN91_03565 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) ACN91_03570 ENOG4108IPT Naphthoate synthase ACN91_03575 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_03580 ENOG4105DTQ mandelate racemase muconate lactonizing ACN91_03590 ENOG4105C19 ABC transporter ACN91_03595 ENOG4105CJZ response regulator ACN91_03620 ENOG41069H0 dihydroorotase EC 3.5.2.3 ACN91_03640 ENOG4105FDP GntR family transcriptional regulator ACN91_03645 ENOG4105C6Z Gluconate ACN91_03695 ENOG41082BM Transcriptional regulator, arsr family ACN91_03710 ENOG41086D8 Transcriptional regulator ACN91_03715 ENOG4105C19 ABC transporter ACN91_03730 ENOG4107ZTW SNARE associated Golgi ACN91_03770 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) ACN91_03775 ENOG4108UGV hypoxanthine phosphoribosyltransferase ACN91_03800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_03805 ENOG4105BZU Histidine kinase ACN91_03810 ENOG4105N67 Proton-coupled thiamine transporter YuaJ ACN91_03850 ENOG41087YS Phage shock protein A ACN91_03890 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ACN91_03895 ENOG4105C4M (Ubiquinol oxidase) subunit I ACN91_03900 ENOG4108V2W Carbonate dehydratase ACN91_03965 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component ACN91_03975 ENOG4105D2X ABC transporter substrate-binding protein ACN91_03990 ENOG4107T7U Sulfatase ACN91_03995 ENOG4107S9D Alpha beta hydrolase ACN91_04000 ENOG4105CH6 catalase ACN91_04005 ENOG4105BZU Histidine kinase ACN91_04010 ENOG4105BZU Histidine kinase ACN91_04085 ENOG4105EPU Molybdenum cofactor synthesis domain protein ACN91_04095 ENOG4105BZF Glycosyl transferase (Group 1 ACN91_04100 ENOG4105YVM Phosphoesterase, PA-phosphatase related ACN91_04105 ENOG4108Z0R Transferase ACN91_04110 ENOG4105E8V Alpha Beta Hydrolase Fold protein ACN91_04140 ENOG4105N5T Radical SAM Protein ACN91_04160 ENOG4105C19 ABC transporter ACN91_04175 ENOG4105NCW Trka-c domain protein ACN91_04180 ENOG4107S91 Sodium hydrogen exchanger ACN91_04185 ENOG410605W Major Facilitator ACN91_04190 ENOG4105C8T Leucyl-tRNA synthetase ACN91_04215 ENOG4108B31 Spore germination protein ACN91_04225 ENOG4105DWV Homoserine O-trans-acetylase ACN91_04235 ENOG41085GJ domain protein ACN91_04255 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ACN91_04260 ENOG4105D06 uba thif-type nad fad binding protein ACN91_04270 ENOG4105CVM Molybdenum cofactor synthesis domain protein ACN91_04275 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein ACN91_04280 ENOG4108ZAF Molybdopterin ACN91_04295 ENOG4105CSC Glucose uptake protein ACN91_04300 ENOG4107EXU Short-chain dehydrogenase reductase Sdr ACN91_04305 ENOG4108VJ1 Transcriptional regulator (CarD family ACN91_04340 ENOG4105CBX hi0933 family ACN91_04355 ENOG4105YW5 deoR family transcriptional regulator ACN91_04360 ENOG4107QSE Dipeptidase ACN91_04375 ENOG4108IUM Glycogen debranching enzyme ACN91_04380 ENOG4108V15 phosphotransferase enzyme family ACN91_04395 ENOG4105C8F Beta-lactamase domain protein ACN91_04400 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) ACN91_04430 ENOG4108VDD TRNA binding domain protein ACN91_04480 ENOG4105C88 aminopeptidase ACN91_04500 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ACN91_04505 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ACN91_04510 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ACN91_04520 ENOG4105ETE Transcriptional regulator (LacI family ACN91_04545 ENOG4105EP9 oxidoreductase ACN91_04550 ENOG4107SNB ankyrin repeat protein YahD ACN91_04555 ENOG4105BZU Histidine kinase ACN91_04560 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_04570 ENOG4106HB6 Alpha beta hydrolase ACN91_04575 ENOG4105DGU Histone deacetylase ACN91_04580 ENOG4105W87 Cbs domain ACN91_04585 ENOG4105F1V Acetoin utilization protein ACN91_04595 ENOG4108UW5 maltose o-acetyltransferase ACN91_04605 ENOG4105EMN RNA polymerase sigma factor ACN91_04640 ENOG4105C28 cystathionine ACN91_04650 ENOG4105U5Y Transcriptional regulator ACN91_04660 ENOG4105RQF LysR family Transcriptional regulator ACN91_04685 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ACN91_04695 ENOG4105EFZ amidohydrolase ACN91_04710 ENOG4105KBJ sporulation protein ytfj ACN91_04715 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) ACN91_04725 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) ACN91_04745 ENOG4108JYZ YitT family ACN91_04785 ENOG4107YZX Universal stress protein ACN91_04805 ENOG41082W1 Cupin 2, conserved barrel domain protein ACN91_04810 ENOG4105Z7P Acetyltransferase (GNAT) family ACN91_04850 ENOG4105DC7 peptidase M24 ACN91_04880 ENOG4105SFS phosphoesterase RecJ domain protein ACN91_04890 ENOG4105VV2 ACN91_04895 ENOG4105C0B DNA polymerase III (alpha subunit) ACN91_04900 ENOG4105C6K Malic enzyme ACN91_04905 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family ACN91_04930 ENOG4105FS0 cytoplasmic membrane protein ACN91_04935 ENOG4108REF Sporulation integral membrane protein ytvi ACN91_04950 ENOG4105BZN citrate synthase ACN91_04955 ENOG4108HMX isocitrate dehydrogenase (NADP) ACN91_04975 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_04980 ENOG4105BZU Histidine kinase ACN91_04985 ENOG4105C2M dna polymerase I ACN91_04990 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) ACN91_05000 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) ACN91_05005 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase ACN91_05010 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) ACN91_05035 ENOG4108TDW sporulation protein YtxC ACN91_05040 ENOG4105C22 threonyL-tRNA synthetase ACN91_05045 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) ACN91_05065 ENOG4105CN9 Peptidase m42 family protein ACN91_05070 ENOG4108JGH Tetr family transcriptional regulator ACN91_05075 ENOG4105CW7 secretion protein, HlyD family ACN91_05080 ENOG4105C0R drug resistance transporter emrb qaca subfamily ACN91_05110 ENOG4108RWN rrna methyltransferase ACN91_05120 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) ACN91_05125 ENOG4105C5S asparaginyl-tRNA synthetase ACN91_05145 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) ACN91_05160 ENOG4105DCG PHP domain protein ACN91_05175 ENOG4105FE9 pseudouridine synthase ACN91_05185 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) ACN91_05195 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) ACN91_05210 ENOG4105E0A ABC, transporter ACN91_05215 ENOG4105KFN sortase, SrtB family ACN91_05225 ENOG4105DR4 Methyltransferase ACN91_05240 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_05290 ENOG4105S6R Iron-hydroxamate transporter permease subunit ACN91_05295 ENOG4105J76 Periplasmic binding protein ACN91_05305 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_05310 ENOG4107Z3H Transcriptional regulator, TetR family ACN91_05315 ENOG41060WC Enoyl-CoA hydratase ACN91_05320 ENOG4105BZJ Electron transfer flavoprotein ACN91_05325 ENOG4105C10 Electron transfer flavoprotein ACN91_05330 ENOG4105K63 Thioredoxin ACN91_05335 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) ACN91_05345 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit ACN91_05355 ENOG4105E33 succinate dehydrogenase ACN91_05365 ENOG4108VXD carboxy-peptidase ACN91_05370 ENOG4105E14 MotA TolQ exbB proton channel ACN91_05375 ENOG4105ER2 Ompa motb domain protein ACN91_05380 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family ACN91_05385 ENOG4108IUX (ABC) transporter ACN91_05390 ENOG4105RHA ABC transporter, permease ACN91_05395 ENOG4108Z40 Transcriptional regulator ACN91_05400 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) ACN91_05410 ENOG4108JCI Transcriptional regulator ACN91_05415 ENOG41067S9 phage shock protein C, PspC ACN91_05420 ENOG4105DZC cytosine deaminase ACN91_05430 ENOG4105PFC Transcriptional regulator ACN91_05440 ENOG4105KBX Transcriptional regulator, TetR family ACN91_05450 ENOG4108PCX Major Facilitator ACN91_05460 ENOG4108XJQ germination protein ACN91_05475 ENOG4105M59 Phosphodiesterase, mj0936 family ACN91_05510 ENOG4108QCI YvbH-like oligomerisation region ACN91_05540 ENOG4108IUQ atp-dependent protease ACN91_05560 ENOG4105K56 Transcriptional regulator ACN91_05585 ENOG4105D52 delta-aminolevulinic acid dehydratase ACN91_05595 ENOG41068KH stage VI sporulation protein D ACN91_05605 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) ACN91_05610 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase ACN91_05630 ENOG4105DFF Rod shape-determining protein mreb ACN91_05635 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) ACN91_05650 ENOG4107QMS site-determining protein ACN91_05665 ENOG4105C03 ribonuclease ACN91_05675 ENOG4105X36 (ribosomal) protein ACN91_05690 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control ACN91_05700 ENOG4105EWM Histidine kinase ACN91_05705 ENOG4105C19 ABC transporter ACN91_05720 ENOG4105CQC Prephenate dehydratase ACN91_05725 ENOG4108RPX mosc domain containing protein ACN91_05740 ENOG4108IYU L-aspartate oxidase ACN91_05745 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase ACN91_05775 ENOG4108HUF Transporter ACN91_05790 ENOG41061AI Protein of unknown function (DUF2905) ACN91_05805 ENOG4105VIE preprotein translocase, subunit YajC ACN91_05815 ENOG4108QG2 Membrane ACN91_05820 ENOG4105CKP Polysaccharide Biosynthesis Protein ACN91_05830 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) ACN91_05835 ENOG41076HS cation diffusion facilitator family transporter ACN91_05840 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) ACN91_05850 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) ACN91_05855 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) ACN91_05870 ENOG4105CUT histidyl-tRNA synthetase ACN91_05880 ENOG4105CUZ uba thif-type nad fad binding protein ACN91_05890 ENOG4108VCI transcription factor, rsfa family ACN91_05895 ENOG4105D1H recombination factor protein RarA ACN91_05905 ENOG4105C3J Cysteine desulfurase ACN91_05910 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) ACN91_05920 ENOG4105C7H Helicase, RecD TraA family ACN91_05925 ENOG41060CR ACN91_05940 ENOG4105C02 permease ACN91_05950 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) ACN91_05970 ENOG4105HHA aminodeoxychorismate lyase ACN91_05975 ENOG4108VQJ O-methyltransferase ACN91_05980 ENOG4105XYU peptidase (U32 family) ACN91_05985 ENOG4105CFP Peptidase U32 ACN91_05995 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) ACN91_06000 ENOG4107XRG penicillin-binding protein ACN91_06030 ENOG4105C28 cystathionine ACN91_06035 ENOG4108EKI Dehydrogenase ACN91_06045 ENOG4108V5C ABC transporter ACN91_06050 ENOG4105S6R Iron-hydroxamate transporter permease subunit ACN91_06090 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase ACN91_06100 ENOG4105MIR Phenylalanine 4-monooxygenase ACN91_06105 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin ACN91_06140 ENOG4108MUZ hydrolase ACN91_06145 ENOG4105KEG ribosomal-protein-alanine acetyltransferase ACN91_06150 ENOG4105G6Z alkaline phosphatase ACN91_06165 ENOG4108TVJ Nitroreductase ACN91_06185 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_06200 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase ACN91_06205 ENOG4105CQW ribosome biogenesis GTPase YqeH ACN91_06215 ENOG410812S Rna-binding protein ACN91_06225 ENOG4108WF2 Metal Dependent Phosphohydrolase ACN91_06235 ENOG4105DXX methyltransferase ACN91_06245 ENOG4105KQC Competence protein ACN91_06250 ENOG4108UK2 deaminase ACN91_06255 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 ACN91_06265 ENOG4105TQK DNA polymerase iii, delta' subunit ACN91_06290 ENOG4105KVH Transcriptional regulator ACN91_06295 ENOG4105CSA Coproporphyrinogen iii oxidase ACN91_06305 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ ACN91_06325 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) ACN91_06330 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) ACN91_06340 ENOG4105KTH gatB Yqey ACN91_06350 ENOG41068P3 sporulation protein YqfC ACN91_06360 ENOG4105C9A Phoh family ACN91_06365 ENOG4105CTJ Metal Dependent Phosphohydrolase ACN91_06370 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) ACN91_06375 ENOG4107YR5 Diacylglycerol kinase ACN91_06380 ENOG4105KG3 cytidine deaminase ACN91_06385 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) ACN91_06415 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) ACN91_06420 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_06435 ENOG4105EGD dinuclear metal center protein, YbgI family ACN91_06460 ENOG41069ZM Protein of unknown function (DUF2624) ACN91_06465 ENOG4108JYZ YitT family ACN91_06470 ENOG4105FDK ABC transporter ACN91_06480 ENOG4105N80 Ferric uptake regulator, Fur family ACN91_06505 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ACN91_06515 ENOG4107RF6 penicillin-binding protein ACN91_06520 ENOG4105EXS phosphate abc transporter ACN91_06525 ENOG4105C8U phosphate abc transporter ACN91_06530 ENOG4105C8U phosphate abc transporter ACN91_06535 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) ACN91_06540 ENOG4108UTW Plays a role in the regulation of phosphate uptake ACN91_06555 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase ACN91_06565 ENOG4105DKQ ROK family ACN91_06575 ENOG4105C5X domain protein ACN91_06595 ENOG4105C28 cystathionine ACN91_06600 ENOG4105C28 cystathionine ACN91_06610 ENOG4105C3R Methionine synthase ACN91_06615 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) ACN91_06650 ENOG4107R6U sodium dicarboxylate symporter ACN91_06735 ENOG4105C0D helicase ACN91_06765 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family ACN91_06810 ENOG41080TC multidrug resistance protein ACN91_06835 ENOG4105WZW rhodanese family ACN91_06840 ENOG41082GG biotin lipoate A B protein ligase ACN91_06870 ENOG4107YBY Hydrolase ACN91_06880 ENOG4105CBJ Metal-dependent enzyme ACN91_06890 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) ACN91_06895 ENOG4105DC7 peptidase M24 ACN91_06920 ENOG4105CD2 stage iii sporulation protein aa ACN91_06925 ENOG4105KR5 Stage iii sporulation protein ACN91_06930 ENOG4108CQH stage III sporulation protein AC ACN91_06935 ENOG4105KQ4 Stage iii sporulation protein ad ACN91_06945 ENOG410644B Stage III sporulation protein af ACN91_06970 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ACN91_06975 ENOG4108ZSR alkaline shock protein ACN91_06985 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) ACN91_07000 ENOG4105CTB Polyprenyl synthetase ACN91_07010 ENOG4105DX0 Hemolysin A ACN91_07015 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) ACN91_07020 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) ACN91_07025 ENOG4105S1Z Stage IV sporulation protein B ACN91_07035 ENOG4107QQR Sporulation ACN91_07050 ENOG4108QXE glycerophosphoryl diester phosphodiesterase ACN91_07060 ENOG4108JUB Transcriptional regulator ACN91_07075 ENOG4107RDP Dehydrogenase ACN91_07080 ENOG4105CKM Branched-chain carboxylic acid kinase ACN91_07095 ENOG4105CPP Dehydrogenase, E1 component ACN91_07100 ENOG4105C7S Dehydrogenase ACN91_07115 ENOG4108QY0 Membrane ACN91_07125 ENOG4105G7B Protein of unknown function (DUF2992) ACN91_07140 ENOG4108HW3 (ABC) transporter ACN91_07145 ENOG4105E5Q amino acid AbC transporter ACN91_07150 ENOG4105CDA abc transporter atp-binding protein ACN91_07155 ENOG4108QEG Membrane ACN91_07160 ENOG4108VZI ErfK ybiS ycfS ynhG family protein ACN91_07175 ENOG4105D9U N-acetyltransferase ACN91_07180 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) ACN91_07200 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic ACN91_07230 ENOG4105EJQ L-serine dehydratase ACN91_07235 ENOG4105II7 pyrroline-5-carboxylate reductase ACN91_07240 ENOG41069FQ Metallo-beta-lactamase superfamily ACN91_07245 ENOG4108IXY short-chain dehydrogenase reductase ACN91_07260 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) ACN91_07275 ENOG4105DBV ornithine carbamoyltransferase ACN91_07300 ENOG4105CGH 5'-nucleotidase ACN91_07305 ENOG4105DFD Na H antiporter ACN91_07315 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ACN91_07330 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ACN91_07335 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) ACN91_07360 ENOG4108R6K riboflavin synthase, subunit alpha ACN91_07365 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) ACN91_07385 ENOG4108YM7 Gcn5-related n-acetyltransferase ACN91_07390 ENOG4105ETE Transcriptional regulator (LacI family ACN91_07400 ENOG4107SKW Inherit from COG: Alpha beta hydrolase ACN91_07420 ENOG4105RHY Pfam:UPF0157 ACN91_07430 ENOG4105CPC Aldo Keto reductase ACN91_07450 ENOG4105MZ9 stage II sporulation protein m ACN91_07455 ENOG4105I3K Ferric uptake regulator, Fur family ACN91_07465 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) ACN91_07490 ENOG4105D7N magnesium and cobalt transport protein CorA ACN91_07525 ENOG4105DVE abc transporter atp-binding protein ACN91_07530 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family ACN91_07535 ENOG4105DZ1 carboxypeptidase ACN91_07540 ENOG41082AN stage II sporulation protein ACN91_07550 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_07555 ENOG4105C8J )-transporter ACN91_07575 ENOG41090VF Stage v sporulation protein ac ACN91_07580 ENOG4105CZ3 stage V sporulation protein ad ACN91_07590 ENOG4105G6R Stage v sporulation protein ae ACN91_07600 ENOG4105J7I hydrolase ACN91_07605 ENOG4105PTM secreted protein ACN91_07610 ENOG4107ZE5 PPIases accelerate the folding of proteins ACN91_07650 ENOG4105CE4 GlcNAc 6-P deacetylase ACN91_07660 ENOG4105FDP GntR family transcriptional regulator ACN91_07670 ENOG4105CID antiterminator ACN91_07685 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) ACN91_07705 ENOG4105BZU Histidine kinase ACN91_07715 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ACN91_07730 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) ACN91_07755 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase ACN91_07775 ENOG4105DTD Dehydrogenase ACN91_07780 ENOG4105K7K Transcriptional regulator ACN91_07815 ENOG4105CHU acetyl-coa acetyltransferase ACN91_07860 ENOG4105CG3 alpha amylase, catalytic region ACN91_07870 ENOG4107FKK extracellular solute-binding protein family 1 ACN91_07880 ENOG4105EG2 ABC transporter, permease ACN91_07885 ENOG4105FKQ transcriptional regulator ACN91_07890 ENOG4105CHM Aminotransferase ACN91_07900 ENOG4108HGU Histidine kinase ACN91_07920 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) ACN91_07960 ENOG4105UIN ACN91_07970 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) ACN91_07985 ENOG4105K6S Short-chain dehydrogenase reductase Sdr ACN91_07990 ENOG4105EPM Diguanylate phosphodiesterase ACN91_08005 ENOG4107IN1 Protein of unknown function (DUF1797) ACN91_08015 ENOG4108XRC Protein of unknown function (DUF458) ACN91_08050 ENOG4107ZYR domain protein ACN91_08055 ENOG4105CN5 Metallo-Beta-Lactamase ACN91_08065 ENOG4108X4Q Hydrolase ACN91_08070 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) ACN91_08085 ENOG4105CPP Dehydrogenase, E1 component ACN91_08135 ENOG4105CXN decarboxylase ACN91_08155 ENOG4105ECY inositol monophosphatase ACN91_08165 ENOG4105CI3 gtp-binding protein typa ACN91_08170 ENOG4105QA2 ACN91_08190 ENOG4108IAB Phoh family ACN91_08205 ENOG4105CNI cell division protein FtsW ACN91_08210 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) ACN91_08260 ENOG4106UY4 Inherit from COG: Scp-like extracellular ACN91_08275 ENOG4107TB6 phosphoglycerate mutase ACN91_08295 ENOG4106H78 methyltransferase ACN91_08305 ENOG4105H20 Sporulation integral membrane protein YlbJ ACN91_08310 ENOG4105D78 K07001 NTE family protein ACN91_08315 ENOG41063PX domain protein ACN91_08325 ENOG4105KNH Nucleic acid-binding protein ACN91_08350 ENOG41074B2 UPF0747 protein ACN91_08365 ENOG4105CJN penicillin-binding protein ACN91_08370 ENOG4105CJN penicillin-binding protein ACN91_08375 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) ACN91_08390 ENOG4105CNI cell division protein FtsW ACN91_08395 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) ACN91_08400 ENOG4105D4A Cell wall formation (By similarity) ACN91_08410 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) ACN91_08415 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) ACN91_08425 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_08435 ENOG4105WR5 sporulation protein, YlmC YmxH family ACN91_08440 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase ACN91_08445 ENOG4105DFA alanine racemase domain protein ACN91_08455 ENOG41067XK integral membrane protein ACN91_08460 ENOG4105DBK s4 domain protein ACN91_08470 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ACN91_08485 ENOG4105C34 Pseudouridine synthase ACN91_08520 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) ACN91_08570 ENOG4105DC7 peptidase M24 ACN91_08580 ENOG4105F23 Fibronectin-binding protein ACN91_08590 ENOG4105DSJ YicC domain protein ACN91_08610 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase ACN91_08615 ENOG4105C25 Primosomal protein n' ACN91_08630 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B ACN91_08640 ENOG4108ZF3 Phosphatase ACN91_08645 ENOG4105D9P serine threonine protein kinase ACN91_08650 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) ACN91_08655 ENOG4105DJV ribulose-phosphate 3-epimerase ACN91_08660 ENOG4105FJ0 thiamine ACN91_08675 ENOG4108ZAA Alkaline-shock protein ACN91_08680 ENOG4105DP4 dak2 domain fusion protein ylov ACN91_08685 ENOG4105CB5 ATP-dependent DNA helicase recG ACN91_08700 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase ACN91_08705 ENOG4105CHR reductase ACN91_08720 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) ACN91_08725 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ACN91_08745 ENOG4105VB6 UPF0109 protein ACN91_08770 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) ACN91_08785 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha ACN91_08790 ENOG4105C79 DNA protecting protein DprA ACN91_08795 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) ACN91_08805 ENOG4108HE4 integrase family ACN91_08835 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) ACN91_08845 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) ACN91_08850 ENOG4105KNE Phosphatidate cytidylyltransferase ACN91_08855 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) ACN91_08860 ENOG4105DZP Membrane-associated zinc metalloprotease ACN91_08870 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) ACN91_08880 ENOG4105CHV Transcription elongation factor NusA ACN91_08885 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination ACN91_08890 ENOG4105VHM ribosomal protein ACN91_08900 ENOG4105W7A Protein of unknown function (DUF503) ACN91_08915 ENOG4105DTN riboflavin biosynthesis protein ribF ACN91_08935 ENOG4105C1V Peptidase, M16 ACN91_08945 ENOG4105E35 Dipicolinate synthase subunit A ACN91_08950 ENOG4108S0H Dipicolinic acid synthetase, b subunit ACN91_08955 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ACN91_08965 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ACN91_08980 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit ACN91_08990 ENOG4105CNU cell division protein FtsK ACN91_09000 ENOG4105FDP GntR family transcriptional regulator ACN91_09005 ENOG4105DIH basic membrane ACN91_09010 ENOG4108JQ9 ABC transporter ACN91_09015 ENOG4105UIB (ABC) transporter ACN91_09035 ENOG4108RKS Short-chain dehydrogenase reductase Sdr ACN91_09040 ENOG4105XZV Protein of unknown function (DUF3243) ACN91_09055 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase ACN91_09085 ENOG4105D48 metallophosphoesterase ACN91_09090 ENOG4105MCT stage V sporulation protein S ACN91_09095 ENOG4108IGT Dipeptidase ACN91_09100 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein ACN91_09105 ENOG4105DQU oxidoreductase, subunit beta ACN91_09140 ENOG410890F Dynamin family ACN91_09145 ENOG4105E0M Sulfatase ACN91_09155 ENOG4105F0V Cell wall hydrolase ACN91_09170 ENOG4105CS2 ec 3.2.1.21 ACN91_09175 ENOG4108S3Y transcriptional regulator ACN91_09195 ENOG41067MG lrgb family ACN91_09235 ENOG4105BZU Histidine kinase ACN91_09265 ENOG4105D03 DNA-3-methyladenine glycosylase II ACN91_09270 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ACN91_09280 ENOG4105CGK Exodeoxyribonuclease III ACN91_09300 ENOG4105E0A ABC, transporter ACN91_09305 ENOG4105NIV Esterase ACN91_09325 ENOG4105VPX protein, conserved in bacteria ACN91_09330 ENOG410681U heavy metal transport detoxification protein ACN91_09335 ENOG4105C59 p-type ATPase ACN91_09345 ENOG4105K70 DNA-binding protein ACN91_09350 ENOG4105TMB Formate nitrite transporter ACN91_09365 ENOG4105C85 amino acid ACN91_09380 ENOG4108SJC Membrane ACN91_09385 ENOG4107QW4 alcohol dehydrogenase ACN91_09390 ENOG4105E98 transcriptional regulator DeoR family ACN91_09395 ENOG4105DE4 1-phosphofructokinase ACN91_09400 ENOG4105DM4 PTS System ACN91_09405 ENOG41069ER domain protein ACN91_09440 ENOG4106F1P AAA ATPase, central domain protein ACN91_09450 ENOG4105EN6 Membrane ACN91_09455 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ACN91_09460 ENOG4105CXI aluminum resistance protein ACN91_09465 ENOG4105KV4 Transcriptional regulator ACN91_09470 ENOG4105C5F glutamine synthetase ACN91_09475 ENOG4105K7K Transcriptional regulator ACN91_09495 ENOG4108SVB resolvase ACN91_09505 ENOG4105CGH 5'-nucleotidase ACN91_09510 ENOG4108HW3 (ABC) transporter ACN91_09545 ENOG4105BZ1 (ABC) transporter ACN91_09550 ENOG4105BZ1 (ABC) transporter ACN91_09590 ENOG41067MG lrgb family ACN91_09595 ENOG4105VAW lrga family ACN91_09600 ENOG4107RSM transcriptional regulator ACN91_09615 ENOG4105CJ1 ABC, transporter ACN91_09625 ENOG4105CH2 amidohydrolase ACN91_09635 ENOG4107QIV Cytochrome c biogenesis protein ACN91_09670 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) ACN91_09695 ENOG4108903 Formimidoylglutamase ACN91_09700 ENOG4108VJ1 Transcriptional regulator (CarD family ACN91_09705 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase ACN91_09710 ENOG4105CBC glutamate synthase ACN91_09715 ENOG4105CK7 Sodium proline symporter ACN91_09720 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase ACN91_09725 ENOG4105FBA Phospholipase Carboxylesterase ACN91_09730 ENOG4105BZU Histidine kinase ACN91_09740 ENOG4107AYK membrAne ACN91_09775 ENOG4108IMY Transcriptional regulator ACN91_09780 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_09785 ENOG4107ZYJ bioY protein ACN91_09790 ENOG4107F3J Amp-dependent synthetase and ligase ACN91_09810 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) ACN91_09820 ENOG4105E5W Transporter ACN91_09850 ENOG4108I0Z Aconitate hydratase ACN91_09855 ENOG4108JJA ABC, transporter ACN91_09865 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ACN91_09870 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) ACN91_09895 ENOG4105W8X HesB YadR YfhF-family protein ACN91_09900 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) ACN91_09905 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase ACN91_09915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_09920 ENOG4105C0H protease ACN91_09925 ENOG4105K4P CoA-binding domain protein ACN91_09935 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) ACN91_09945 ENOG4105D9R oxidoreductase ACN91_09965 ENOG4105CIG ABC transporter ACN91_09975 ENOG4105EMN RNA polymerase sigma factor ACN91_09985 ENOG4108KGH TRANSCRIPTIONal ACN91_10040 ENOG4105CUB amino acid ACN91_10055 ENOG4105E1K spore germination protein ACN91_10065 ENOG4108JB9 formate dehydrogenase ACN91_10075 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) ACN91_10080 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) ACN91_10090 ENOG4105TMB Formate nitrite transporter ACN91_10095 ENOG4105D06 uba thif-type nad fad binding protein ACN91_10100 ENOG4105CVM Molybdenum cofactor synthesis domain protein ACN91_10105 ENOG4108ZAF Molybdopterin ACN91_10115 ENOG4105D1F ATP-binding protein ACN91_10130 ENOG410696E Membrane ACN91_10135 ENOG4105FR1 rard protein ACN91_10145 ENOG4105EWU Squalene--hopene cyclase ACN91_10155 ENOG4105CHR reductase ACN91_10160 ENOG4105C26 Dehydrogenase ACN91_10170 ENOG4108IA2 Sodium pantothenate symporter ACN91_10185 ENOG4106IQC argininosuccinate lyase ACN91_10195 ENOG410904N short-chain dehydrogenase reductase ACN91_10215 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) ACN91_10235 ENOG4105VEQ Cold shock protein ACN91_10255 ENOG4108R1P ACN91_10265 ENOG41073R8 VanW family ACN91_10270 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase ACN91_10285 ENOG4105KT7 mgtC SapB transporter ACN91_10295 ENOG4105BZU Histidine kinase ACN91_10315 ENOG4107DUR UPF0457 protein ACN91_10330 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity ACN91_10335 ENOG41067SE Tetr family transcriptional regulator ACN91_10340 ENOG4105C5H ABC transporter ACN91_10345 ENOG4105BZU Histidine kinase ACN91_10385 ENOG4105E1K spore germination protein ACN91_10395 ENOG4108M1A Chitin-binding protein ACN91_10400 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C ACN91_10425 ENOG4105CQB FAD linked oxidase domain protein ACN91_10455 ENOG4105CNG UPF0061 protein ACN91_10460 ENOG4105CIS alcohol dehydrogenase ACN91_10465 ENOG41082BM Transcriptional regulator, arsr family ACN91_10510 ENOG4107VXM glycerophosphoryl diester phosphodiesterase ACN91_10535 ENOG4108A04 Beta-lactamase ACN91_10550 ENOG4105FFC UPF0187 protein ACN91_10570 ENOG4105DPN Oligoendopeptidase f ACN91_10575 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase ACN91_10580 ENOG4105E5K Alpha-amylase ACN91_10590 ENOG4105C98 muts2 protein ACN91_10610 ENOG4107V2S Transcriptional regulator ACN91_10620 ENOG4107CUJ Protein of unknown function (DUF2690) ACN91_10640 ENOG4105NX3 Membrane ACN91_10645 ENOG4105DQ5 transport system permease protein ACN91_10650 ENOG4105EHG Permease protein ACN91_10655 ENOG4108MES Periplasmic binding protein ACN91_10670 ENOG4107R3E Citrate transporter ACN91_10680 ENOG4108TN2 lmbE family ACN91_10745 ENOG4105H3G oxidoreductase ACN91_10775 ENOG4107YXZ hydrolase, family 25 ACN91_10785 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) ACN91_10860 ENOG4108ZJ4 polysaccharide deacetylase ACN91_10875 ENOG4105KVH Transcriptional regulator ACN91_10880 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein ACN91_10900 ENOG4105CHR reductase ACN91_10910 ENOG4105JAB phenazine biosynthesis protein, phzf family ACN91_10955 ENOG4105KVH Transcriptional regulator ACN91_10960 ENOG4105KVH Transcriptional regulator ACN91_10965 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase ACN91_10970 ENOG4105D9R oxidoreductase ACN91_10975 ENOG4108TZY GntR Family Transcriptional Regulator ACN91_10980 ENOG4105KVH Transcriptional regulator ACN91_11015 ENOG4105C44 Serine transporter ACN91_11030 ENOG4105CHH sulfate transporter ACN91_11035 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA ACN91_11050 ENOG41090KN UPF0303 protein ACN91_11060 ENOG4105F27 Major Facilitator ACN91_11065 ENOG4105CV8 reductase ACN91_11080 ENOG4105EWI Short-chain dehydrogenase reductase Sdr ACN91_11095 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone ACN91_11100 ENOG4105CIS alcohol dehydrogenase ACN91_11105 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ACN91_11110 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase ACN91_11115 ENOG4105CV1 Transketolase (EC 2.2.1.1) ACN91_11130 ENOG4105C6Z Gluconate ACN91_11135 ENOG4105CMG Carbohydrate kinase ACN91_11140 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) ACN91_11145 ENOG4105XDF Protein of unknown function (DUF1272) ACN91_11150 ENOG4105DDN Pentapeptide repeat-containing protein ACN91_11180 ENOG4105FAW cDP-glucose 4,6-dehydratase ACN91_11185 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase ACN91_11200 ENOG4105C37 (CBS) domain ACN91_11260 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) ACN91_11265 ENOG4105C31 Tryptophanyl-tRNA synthetase ACN91_11270 ENOG4108UW5 maltose o-acetyltransferase ACN91_11280 ENOG4105DKQ ROK family ACN91_11355 ENOG4108PSK reductase ACN91_11385 ENOG4108RCM Nitroreductase ACN91_11390 ENOG4105KVH Transcriptional regulator ACN91_11405 ENOG4105CUT histidyl-tRNA synthetase ACN91_11410 ENOG4108Z66 YbaK ebsC protein ACN91_11435 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) ACN91_11445 ENOG4108K8S endonuclease I ACN91_11505 ENOG4105DYS nad(p)h dehydrogenase (quinone) ACN91_11515 ENOG4105CRW Short chain fatty acid transporter ACN91_11540 ENOG4105CZM Major Facilitator ACN91_11545 ENOG4107MII Sugar-specific transcriptional regulator TrmB ACN91_11560 ENOG4108ISG Major Facilitator ACN91_11570 ENOG4105PNM synthesis protein ACN91_11575 ENOG4108VXD carboxy-peptidase ACN91_11595 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ACN91_11615 ENOG410874W AraC family transcriptional regulator ACN91_11620 ENOG41082W1 Cupin 2, conserved barrel domain protein ACN91_11635 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) ACN91_11640 ENOG4108JQ1 Dehydrogenase ACN91_11660 ENOG4105DVH amino acid ACN91_11670 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) ACN91_11685 ENOG4108JPW Aminotransferase ACN91_11700 ENOG4105EJQ L-serine dehydratase ACN91_11705 ENOG4105C44 Serine transporter ACN91_11750 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A ACN91_11765 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) ACN91_11775 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 ACN91_11780 ENOG4108U05 Transcriptional regulator ACN91_11795 ENOG4105BZU Histidine kinase ACN91_11815 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) ACN91_11835 ENOG4105JQZ Methyltransferase ACN91_11845 ENOG4105E0Y RtcB Protein ACN91_11855 ENOG4105K6H D-cysteine desulfhydrase ACN91_11880 ENOG4105C0R drug resistance transporter emrb qaca subfamily ACN91_11885 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) ACN91_11915 ENOG4105C19 ABC transporter ACN91_11955 ENOG41062D9 Histidine kinase ACN91_11960 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_12075 ENOG4108YXU transcriptional regulator AsnC family ACN91_12080 ENOG4105CHR reductase ACN91_12085 ENOG4105M4P Tetr family transcriptional regulator ACN91_12090 ENOG4105F27 Major Facilitator ACN91_12145 ENOG4108IG5 Transcriptional regulator ACN91_12150 ENOG4107P5I polyketide synthase ACN91_12155 ENOG4105NAE bifunctional deaminase-reductase domain protein ACN91_12170 ENOG41085FC arsR family transcriptional regulator ACN91_12175 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase ACN91_12180 ENOG4105D6J arsenicaL-resistance protein ACN91_12190 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase ACN91_12195 ENOG4105KY5 gCN5-related N-acetyltransferase ACN91_12200 ENOG4107VMI polysaccharide deacetylase ACN91_12205 ENOG4105E1K spore germination protein ACN91_12220 ENOG4105GPN Uncharacterized conserved protein (DUF2294) ACN91_12225 ENOG4108TWJ NADH dehydrogenase subunit 5 ACN91_12250 ENOG4105CVP deoxyribo-dipyrimidine photolyase ACN91_12255 ENOG4108606 TspO/MBR family ACN91_12270 ENOG4105E1K spore germination protein ACN91_12330 ENOG41090MY MarR family Transcriptional regulator ACN91_12355 ENOG4105CHJ isochorismatase hydrolase ACN91_12365 ENOG4105CGH 5'-nucleotidase ACN91_12385 ENOG4108FPN Integrase ACN91_12485 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 ACN91_12510 ENOG4105CN5 Metallo-Beta-Lactamase ACN91_12520 ENOG4105E2A Dehydrogenase ACN91_12545 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) ACN91_12590 ENOG4105DWD nucleoside recognition domain protein ACN91_12605 ENOG4105FDT acyl-CoA dehydrogenase ACN91_12615 ENOG4108ZHR arsR family transcriptional regulator ACN91_12620 ENOG4106N3A copper homeostasis protein cutc ACN91_12635 ENOG4107258 Transcriptional regulator ACN91_12640 ENOG4105P4J Allophanate hydrolase, subunit 1 ACN91_12650 ENOG4105E7W lamb ycsf family protein ACN91_12665 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) ACN91_12670 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) ACN91_12675 ENOG4107RF6 penicillin-binding protein ACN91_12715 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) ACN91_12725 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_12730 ENOG4105BZU Histidine kinase ACN91_12740 ENOG4105F1N DNA alkylation repair ACN91_12750 ENOG4108IQI permease ACN91_12760 ENOG410635A Membrane ACN91_12780 ENOG4105RHY Pfam:UPF0157 ACN91_12820 ENOG4108PCN EamA-like transporter family ACN91_12835 ENOG4108XET gCN5-related N-acetyltransferase ACN91_12840 ENOG4108DMH HTH_ARAC ACN91_12865 ENOG4105C19 ABC transporter ACN91_12875 ENOG4105WEC Molybdate metabolism regulator ACN91_12895 ENOG4105FS7 Transcriptional regulator ACN91_12900 ENOG4108TVJ Nitroreductase ACN91_12940 ENOG4105C8Y Acetylornithine aminotransferase ACN91_12960 ENOG4105C7R Atpase associated with various cellular activities aaa_3 ACN91_12990 ENOG41068WN ACN91_13015 ENOG4105VMP Transcriptional regulator ACN91_13025 ENOG4105G6Z alkaline phosphatase ACN91_13030 ENOG4107RBI VanW family ACN91_13040 ENOG4105ECK Fatty Acid Desaturase ACN91_13060 ENOG4107258 Transcriptional regulator ACN91_13070 ENOG4105II7 pyrroline-5-carboxylate reductase ACN91_13100 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) ACN91_13110 ENOG41061GT Aldolase ACN91_13120 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) ACN91_13125 ENOG4105DKT Transcriptional regulator ACN91_13135 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane ACN91_13140 ENOG4105F5R ABC transporter ACN91_13145 ENOG4105D4B ABC, transporter ACN91_13170 ENOG4105JVQ RNA Polymerase ACN91_13180 ENOG41082JN Transcriptional regulator ACN91_13190 ENOG4105DNP FAD linked oxidase domain protein ACN91_13200 ENOG41069ER domain protein ACN91_13245 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase ACN91_13250 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase ACN91_13275 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) ACN91_13280 ENOG41082JN Transcriptional regulator ACN91_13285 ENOG4105EYF MMPL domain protein ACN91_13290 ENOG4105C5H ABC transporter ACN91_13295 ENOG4105E0M Sulfatase ACN91_13300 ENOG4108ZCF integral membrane protein ACN91_13310 ENOG4107VMI polysaccharide deacetylase ACN91_13325 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase ACN91_13330 ENOG4105C6T cysteine synthase ACN91_13335 ENOG4107VC0 DNA alkylation repair enzyme ACN91_13375 ENOG4108AQF aminoglycoside N(3)-acetyltransferase ACN91_13410 ENOG4105D7T ABC transporter ACN91_13415 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein ACN91_13420 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component ACN91_13425 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) ACN91_13440 ENOG4105C02 permease ACN91_13500 ENOG4105DVE abc transporter atp-binding protein ACN91_13515 ENOG4108ZMI UPF0477 protein ACN91_13530 ENOG4105CHM Aminotransferase ACN91_13565 ENOG41089UC methyltransferase, type 11 ACN91_13580 ENOG4107BMA Transglycosylase associated protein ACN91_13605 ENOG4106K7D Major facilitator family transporter ACN91_13610 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) ACN91_13670 ENOG4105EPR degv family ACN91_13675 ENOG4105DPN Oligoendopeptidase f ACN91_13695 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 ACN91_13715 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_13720 ENOG4105BZU Histidine kinase ACN91_13725 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ACN91_13730 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) ACN91_13760 ENOG4107SET aldo keto reductase ACN91_13775 ENOG4105DTQ mandelate racemase muconate lactonizing ACN91_13790 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD ACN91_13800 ENOG4107T5V SNARE associated Golgi ACN91_13805 ENOG4105DCI Phosphohydrolase ACN91_13850 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein ACN91_13860 ENOG41080HI glycine oxidase ACN91_13865 ENOG4105CTU Proline racemase ACN91_13870 ENOG4105CTU Proline racemase ACN91_13875 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) ACN91_13880 ENOG4105C26 Dehydrogenase ACN91_13885 ENOG4105BZG amino acid carrier protein ACN91_13905 ENOG4108M1A Chitin-binding protein ACN91_13960 ENOG4105C9U ATP-dependent DNA helicase RecQ ACN91_13980 ENOG4105EEM helicase ACN91_14005 ENOG4108Z7F N-acetyltransferase ACN91_14025 ENOG4105MSB protein, conserved in bacteria ACN91_14055 ENOG4108M1A Chitin-binding protein ACN91_14065 ENOG41082BV acetyltransferase ACN91_14070 ENOG4105E66 phosphoriboisomerase A ACN91_14095 ENOG4108IJ7 Glycine betaine ACN91_14100 ENOG4107SQ8 Glycine betaine ACN91_14140 ENOG4105RHY Pfam:UPF0157 ACN91_14145 ENOG4105E1F short-chain dehydrogenase reductase ACN91_14155 ENOG4107RUY (E1 component), alpha subunit ACN91_14165 ENOG4107QKR Dehydrogenase ACN91_14185 ENOG41062ES Transcriptional regulator ACN91_14200 ENOG4105E98 transcriptional regulator DeoR family ACN91_14220 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family ACN91_14245 ENOG4107Z3H Transcriptional regulator, TetR family ACN91_14250 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) ACN91_14255 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) ACN91_14285 ENOG4105MSI germination protein ypeb ACN91_14330 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) ACN91_14335 ENOG4105CIS alcohol dehydrogenase ACN91_14345 ENOG4105FDR Membrane ACN91_14350 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) ACN91_14360 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ACN91_14385 ENOG4108IUM Glycogen debranching enzyme ACN91_14400 ENOG4105DY8 decarboxylase ACN91_14415 ENOG4107WD8 ABC transporter, permease ACN91_14435 ENOG4105BZU Histidine kinase ACN91_14440 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_14445 ENOG4105U0R haloacid dehalogenase-like hydrolase ACN91_14470 ENOG4107VFR oxidoreductase ACN91_14510 ENOG4105PKS Excinuclease abc c subunit domain protein ACN91_14535 ENOG4108YYS metal-dependent hydrolase (By similarity) ACN91_14545 ENOG4105KWG Pfam:DUF1696 ACN91_14550 ENOG4108NRW Phospholipase, patatin family ACN91_14570 ENOG4108XI2 Domain of unknown function (DUF1963) ACN91_14575 ENOG4105KME endoribonuclease L-psp ACN91_14600 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) ACN91_14605 ENOG4105E09 nadh pyrophosphatase ACN91_14615 ENOG4105FCD Major Facilitator ACN91_14660 ENOG4107Y9U Membrane ACN91_14685 ENOG4107VXM glycerophosphoryl diester phosphodiesterase ACN91_14705 ENOG4108Z5V transcriptional regulator, merr family ACN91_14710 ENOG4107Y80 Major Facilitator superfamily ACN91_14760 ENOG4105CJN penicillin-binding protein ACN91_14765 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase ACN91_14770 ENOG4105CB2 alcohol dehydrogenase ACN91_14835 ENOG4108HGU Histidine kinase ACN91_14845 ENOG4108JJB ABC transporter ACN91_14870 ENOG4107RF6 penicillin-binding protein ACN91_14875 ENOG4105BZU Histidine kinase ACN91_14880 ENOG410667J hydrolase ACN91_14965 ENOG4105XSJ toxin secretion phage lysis holin ACN91_15255 ENOG4105VTR Integrase ACN91_15280 ENOG4105ETU transcriptional activator (TenA ACN91_15285 ENOG4105CPF Cell wall formation (By similarity) ACN91_15295 ENOG4105D6E homoserine dehydrogenase ACN91_15365 ENOG4105DK7 lysyl-tRNA synthetase ACN91_15375 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein ACN91_15390 ENOG410900G Protein of unknown function (DUF421) ACN91_15400 ENOG4105CPQ Dehydrogenase ACN91_15465 ENOG4105KVH Transcriptional regulator ACN91_15470 ENOG41061TZ Short-chain dehydrogenase reductase Sdr ACN91_15480 ENOG4107Y80 Major Facilitator superfamily ACN91_15485 ENOG4108V4B ThiJ pfpI ACN91_15500 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) ACN91_15530 ENOG41075H3 AraC family transcriptional regulator ACN91_15550 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) ACN91_15565 ENOG4105T9C HD domain ACN91_15580 ENOG4105DZ1 carboxypeptidase ACN91_15600 ENOG4105DBI uridine monophosphokinase ACN91_15620 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) ACN91_15625 ENOG4107QX3 carboxylase ACN91_15630 ENOG4105E39 Enoyl-CoA hydratase ACN91_15635 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase ACN91_15640 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit ACN91_15645 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase ACN91_15650 ENOG4105C1G acyl-Coa dehydrogenase ACN91_15665 ENOG4107Z3H Transcriptional regulator, TetR family ACN91_15675 ENOG4105CJ1 ABC, transporter ACN91_15685 ENOG4105DIN metallophosphoesterase ACN91_15700 ENOG4107RF6 penicillin-binding protein ACN91_15705 ENOG4107RF6 penicillin-binding protein ACN91_15720 ENOG4107RVG penicillin-binding protein ACN91_15725 ENOG4105FQP Beta-lactamase ACN91_15730 ENOG4107SCK Monooxygenase ACN91_15785 ENOG4107S9D Alpha beta hydrolase ACN91_15795 ENOG4105BZU Histidine kinase ACN91_15820 ENOG41075H3 AraC family transcriptional regulator ACN91_15830 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) ACN91_15835 ENOG4105CUB amino acid ACN91_15840 ENOG4105II7 pyrroline-5-carboxylate reductase ACN91_15845 ENOG4108NHD germination protein ACN91_15850 ENOG4108Q8B Spore germination protein ACN91_15895 ENOG4105W8Z 4'-phosphopantetheinyl transferase ACN91_15935 ENOG4105EQK -acetyltransferase ACN91_15940 ENOG4105EJ9 Membrane ACN91_15950 ENOG4105KRN Transcriptional regulator, abrb family ACN91_15980 ENOG4105CIN aminoacyl-histidine dipeptidase ACN91_16005 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) ACN91_16010 ENOG4105K56 Transcriptional regulator ACN91_16015 ENOG4107RA9 decarboxylase ACN91_16020 ENOG4108I0C methyltransferase ACN91_16030 ENOG41088CC tellurite resistance protein tehB ACN91_16035 ENOG4105C1J atp-dependent rna helicase ACN91_16050 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ACN91_16065 ENOG4108INS Transcriptional regulator ACN91_16070 ENOG4105C7B Threonine dehydratase ACN91_16080 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) ACN91_16085 ENOG4105RD7 BadF BadG BcrA BcrD ACN91_16090 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) ACN91_16110 ENOG4105F32 YngK protein ACN91_16135 ENOG4108KPJ rna polymerase sigma factor ACN91_16140 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) ACN91_16175 ENOG4108JCI Transcriptional regulator ACN91_16210 ENOG4105BZ1 (ABC) transporter ACN91_16215 ENOG4105BZ1 (ABC) transporter ACN91_16230 ENOG4108RPX mosc domain containing protein ACN91_16235 ENOG4105DND Transcriptional regulator ACN91_16255 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) ACN91_16260 ENOG4107V2S Transcriptional regulator ACN91_16290 ENOG41068WN ACN91_16300 ENOG4105C1Q protoporphyrinogen oxidase ACN91_16325 ENOG4105WCN acetyltransferase ACN91_16350 ENOG4105EYF MMPL domain protein ACN91_16360 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) ACN91_16375 ENOG4108Y4K DNA-binding transcriptional activator ACN91_16385 ENOG41081I9 integral membrane protein ACN91_16400 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) ACN91_16435 ENOG4105C19 ABC transporter ACN91_16440 ENOG4105C22 threonyL-tRNA synthetase ACN91_16445 ENOG4105FE9 pseudouridine synthase ACN91_16465 ENOG4105BZG amino acid carrier protein ACN91_16485 ENOG4105K70 DNA-binding protein ACN91_16500 ENOG4105C0R drug resistance transporter emrb qaca subfamily ACN91_16505 ENOG4105WQT MbtH domain protein ACN91_16510 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_16515 ENOG4105WQI isochorismatase ACN91_16520 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase ACN91_16525 ENOG4105E4F Isochorismate synthase ACN91_16530 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase ACN91_16535 ENOG4105FCD Major Facilitator ACN91_16560 ENOG4105EYH Exonuclease ACN91_16565 ENOG4107RFY SbcCD D subunit ACN91_16580 ENOG4105E39 Enoyl-CoA hydratase ACN91_16585 ENOG4105N14 lysine exporter protein LysE YggA ACN91_16595 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase ACN91_16600 ENOG4105C1G acyl-Coa dehydrogenase ACN91_16605 ENOG4105CR4 methylisocitrate lyase ACN91_16610 ENOG4105DXD 2-methylcitrate dehydratase ACN91_16620 ENOG4105W8X HesB YadR YfhF-family protein ACN91_16625 ENOG4105CZM Major Facilitator ACN91_16635 ENOG4105BZ4 penicillin-binding protein ACN91_16655 ENOG4105CHR reductase ACN91_16690 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ACN91_16730 ENOG4105KNA -acetyltransferase ACN91_16735 ENOG4105SZ6 Thioredoxin ACN91_16745 ENOG410841Q phosphoesterase PA-phosphatase related protein ACN91_16855 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein ACN91_16860 ENOG4108JUB Transcriptional regulator ACN91_16865 ENOG4108TSC N-acetyltransferase ACN91_16870 ENOG4107S4Y M20 DapE family protein YgeY ACN91_16885 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ACN91_16910 ENOG4105C37 (CBS) domain ACN91_16945 ENOG4105E90 ABC transporter ACN91_16950 ENOG4108IJ8 ABC transporter ACN91_16990 ENOG4105C6Z Gluconate ACN91_16995 ENOG4105CMG Carbohydrate kinase ACN91_17015 ENOG4107ZY0 Phenazine biosynthesis-like protein ACN91_17020 ENOG4106KNT transcriptional regulator ACN91_17025 ENOG4105WH1 Two component transcriptional regulator luxr family ACN91_17030 ENOG4105BZU Histidine kinase ACN91_17035 ENOG4105D8X mechanosensitive ion channel ACN91_17065 ENOG4105F0I Aminotransferase ACN91_17070 ENOG4108MES Periplasmic binding protein ACN91_17075 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase ACN91_17090 ENOG4105CAQ asparagine synthetase ACN91_17095 ENOG4107Y70 Heat shock protein ACN91_17100 ENOG4108KF3 Electron transport protein SCO1 SenC ACN91_17110 ENOG4108RCR degv family ACN91_17120 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) ACN91_17130 ENOG4108UT2 hemolysin iii ACN91_17135 ENOG4105E9Q Acyl-transferase ACN91_17145 ENOG4107RVG penicillin-binding protein ACN91_17155 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) ACN91_17160 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) ACN91_17175 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 ACN91_17200 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase ACN91_17205 ENOG4105VMP Transcriptional regulator ACN91_17215 ENOG4105KD7 acetyltransferase ACN91_17235 ENOG4105CY2 Citrate transporter ACN91_17240 ENOG4107XGZ Hydrolase ACN91_17260 ENOG4105C8J )-transporter ACN91_17265 ENOG4106849 propeptide, pepSY amd peptidase M4 ACN91_17275 ENOG41062D9 Histidine kinase ACN91_17280 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_17285 ENOG4107QPK )-transporter ACN91_17290 ENOG4105BZW Glycerate kinase ACN91_17340 ENOG4105EC2 ftsk spoIIIe ACN91_17360 ENOG4105C5S asparaginyl-tRNA synthetase ACN91_17385 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) ACN91_17400 ENOG4105C75 arginyL-tRNA synthetase ACN91_17405 ENOG4107YX5 Pfam:DUF548 ACN91_17430 ENOG4108UUM single-stranded DNA-binding protein ACN91_17445 ENOG4105C5H ABC transporter ACN91_17460 ENOG4108IBT Inherit from COG: transposase ACN91_17470 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ACN91_17490 ENOG4105MCT stage V sporulation protein S ACN91_17525 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) ACN91_17530 ENOG4108IFG nitrite reductase, (NAD(P)H) ACN91_17535 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit ACN91_17540 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ACN91_17545 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein ACN91_17550 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein ACN91_17580 ENOG4108ZAF Molybdopterin ACN91_17585 ENOG4105CVM Molybdenum cofactor synthesis domain protein ACN91_17590 ENOG4105D06 uba thif-type nad fad binding protein ACN91_17595 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) ACN91_17600 ENOG4107V6Q Cyclic nucleotide-binding domain ACN91_17610 ENOG4105R3A Nitrate reductase ACN91_17615 ENOG4108IUE nitrate reductase beta subunit ACN91_17625 ENOG4105C7R Atpase associated with various cellular activities aaa_3 ACN91_17640 ENOG4108V06 Glutathione peroxidase ACN91_17650 ENOG4105CNW domain protein ACN91_17665 ENOG4105EMN RNA polymerase sigma factor ACN91_17670 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein ACN91_17680 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ACN91_17705 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ACN91_17730 ENOG4105KBJ sporulation protein ytfj ACN91_17755 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) ACN91_17785 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ACN91_17790 ENOG4108JYZ YitT family ACN91_17795 ENOG41087PP glycosyltransferase MGT family ACN91_17810 ENOG4107RBS Methyltransferase ACN91_17815 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ACN91_17825 ENOG4105D94 Major Facilitator Superfamily ACN91_17830 ENOG41082F9 transcriptional regulator ACN91_17835 ENOG4108X4Q Hydrolase ACN91_17845 ENOG4108ZRV stage ii sporulation protein p ACN91_17875 ENOG4108VXD carboxy-peptidase ACN91_17885 ENOG4108ZRV stage ii sporulation protein p ACN91_17905 ENOG4108Z7R Chaperone CsaA ACN91_17935 ENOG4105C37 (CBS) domain ACN91_17940 ENOG4105SXS Protein of unknown function (DUF456) ACN91_17960 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ACN91_17965 ENOG4108S4H thioesterase Superfamily protein ACN91_17975 ENOG4108PJD permease ACN91_17990 ENOG4107T5V SNARE associated Golgi ACN91_18035 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) ACN91_18045 ENOG4105K4T epimerase ACN91_18055 ENOG4105DSE periplasmic solute binding protein ACN91_18065 ENOG4105CKI cobalamin synthesis protein ACN91_18075 ENOG4107QM2 Aldo Keto reductase ACN91_18080 ENOG4105VMI -acetyltransferase ACN91_18095 ENOG4105DEN Luciferase family ACN91_18110 ENOG4108WPJ Ferritin-like domain ACN91_18115 ENOG4108K88 Membrane ACN91_18135 ENOG4105C8Q Methyl-accepting chemotaxis ACN91_18160 ENOG4107XZQ multidrug resistance protein ACN91_18165 ENOG4105CPC Aldo Keto reductase ACN91_18170 ENOG4105YVS arsR family transcriptional regulator ACN91_18180 ENOG4105KRN Transcriptional regulator, abrb family ACN91_18230 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ACN91_18235 ENOG4108ZUB Lysine exporter protein (Lyse ygga) ACN91_18245 ENOG4105YWU small acid-soluble spore protein ACN91_18250 ENOG4108WBH protein TIM barrel ACN91_18265 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_18270 ENOG4105DUU IucA IucC family protein ACN91_18280 ENOG4105VRR gCN5-related N-acetyltransferase ACN91_18285 ENOG4105KT7 mgtC SapB transporter ACN91_18295 ENOG4107VMI polysaccharide deacetylase ACN91_18300 ENOG4105BZU Histidine kinase ACN91_18305 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_18315 ENOG4108KGH TRANSCRIPTIONal ACN91_18330 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) ACN91_18340 ENOG4105D6E homoserine dehydrogenase ACN91_18360 ENOG4108ZJ4 polysaccharide deacetylase ACN91_18365 ENOG41075D4 Aminoglycoside 6-adenylyltransferase ACN91_18385 ENOG4105BZU Histidine kinase ACN91_18390 ENOG4105EFI regulatoR ACN91_18395 ENOG4105BZ1 (ABC) transporter ACN91_18445 ENOG4108UT6 Transferase hexapeptide repeat containing protein ACN91_18455 ENOG4105K64 Glycosyl transferase, family 2 ACN91_18465 ENOG4108JJ8 (ABC) transporter ACN91_18470 ENOG4108JJ9 ABC, transporter ACN91_18475 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii ACN91_18480 ENOG4105C4M (Ubiquinol oxidase) subunit I ACN91_18500 ENOG4105MDS 4-oxalocrotonate tautomerase ACN91_18510 ENOG4105EGI Transcriptional regulator ACN91_18520 ENOG4105C32 Amino acid ABC transporter (Permease) ACN91_18525 ENOG4108IV0 ABC, transporter ACN91_18530 ENOG4105C0Z ABC transporter ACN91_18540 ENOG4105CKI cobalamin synthesis protein ACN91_18550 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) ACN91_18555 ENOG4106F5Q Membrane ACN91_18560 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) ACN91_18570 ENOG4108TVJ Nitroreductase ACN91_18575 ENOG4107ZXU DSBA oxidoreductase ACN91_18580 ENOG4108Z40 Transcriptional regulator ACN91_18585 ENOG4105GZI Transcriptional regulator ACN91_18590 ENOG4107RT3 EamA-like transporter family ACN91_18595 ENOG4105KTB nuclear export factor GLE1 ACN91_18600 ENOG4108T5E Copper resistance protein ACN91_18605 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase ACN91_18640 ENOG4107R16 Multicopper oxidase ACN91_18650 ENOG4107RAQ aminopeptidase ACN91_18665 ENOG410811B TRANSCRIPTIONal ACN91_18695 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) ACN91_18700 ENOG4105D9N nucleoside ACN91_18710 ENOG4107RHR regulatoR ACN91_18720 ENOG4108TYN CAAX amino terminal protease family protein ACN91_18725 ENOG4105K8R UPF0145 protein ACN91_18730 ENOG410849A acetyltransferase, (GNAT) family ACN91_18775 ENOG4105C0X amino acid ACN91_18785 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) ACN91_18800 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) ACN91_18820 ENOG41068WN ACN91_18830 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) ACN91_18840 ENOG4105K5X acetyltransferase ACN91_18845 ENOG4105CYC Transferase ACN91_18850 ENOG4105DY9 regulatoR ACN91_18860 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b ACN91_18865 ENOG4105C6X Major Facilitator ACN91_18885 ENOG4105C7B Threonine dehydratase ACN91_18895 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase ACN91_18905 ENOG4105C7K acetolactate synthase ACN91_18910 ENOG4105CM2 brancheD-chain amino acid aminotransferase ACN91_18915 ENOG4105CHR reductase ACN91_18920 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) ACN91_18940 ENOG4105H67 Protein of unknown function (DUF421) ACN91_18945 ENOG4105X5K response regulator receiver protein ACN91_18955 ENOG4105C8J )-transporter ACN91_18970 ENOG4105C6T cysteine synthase ACN91_18975 ENOG4105EU0 Major facilitator Superfamily ACN91_18980 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) ACN91_18995 ENOG4105DXI Major Facilitator superfamily ACN91_19005 ENOG4105U3E Transcriptional regulator ACN91_19010 ENOG4105CSR polyphosphate kinase 2 ACN91_19025 ENOG4105FVX ACN91_19090 ENOG4105C6K Malic enzyme ACN91_19095 ENOG4108IJ0 Aspartate ammonia-lyase ACN91_19105 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) ACN91_19125 ENOG4105CJ1 ABC, transporter ACN91_19160 ENOG4106BRA Membrane ACN91_19165 ENOG4105BZC d-serine deaminase ACN91_19180 ENOG4107JM4 Tetratricopeptide repeat ACN91_19195 ENOG4107QIV Cytochrome c biogenesis protein ACN91_19215 ENOG4105EC3 peptidase S51, dipeptidase E ACN91_19220 ENOG4107QJQ Mate efflux family protein ACN91_19245 ENOG4105C9Q fumarate hydratase class II ACN91_19255 ENOG4105VUF Transcriptional regulator ACN91_19260 ENOG4105DFD Na H antiporter ACN91_19275 ENOG4108PJD permease ACN91_19280 ENOG4105CKI cobalamin synthesis protein ACN91_19290 ENOG4108UZ3 Transporter ACN91_19295 ENOG4105DRR Transcriptional regulator, GntR family ACN91_19305 ENOG4105PGM cation diffusion facilitator family transporter ACN91_19325 ENOG4105CAQ asparagine synthetase ACN91_19345 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) ACN91_19355 ENOG4105CVJ phosphoglycerate mutase ACN91_19395 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component ACN91_19405 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ACN91_19410 ENOG4105DUM transcriptional regulator, lysR family ACN91_19435 ENOG4107QZ7 Cellulose synthase catalytic subunit ACN91_19440 ENOG4105KAC Antibiotic biosynthesis monooxygenase ACN91_19480 ENOG4105CPU Monooxygenase ACN91_19485 ENOG4105KTQ flagellar basal-body rod protein ACN91_19490 ENOG4105FZW flagellar biosynthesis regulator FlhF ACN91_19495 ENOG4105D7B Flagellar biosynthesis protein flha ACN91_19500 ENOG4105D00 flagellar biosynthetic protein flhB ACN91_19510 ENOG4105VS8 Flagellar biosynthetic protein fliq ACN91_19515 ENOG4105CN7 Flagellar biosynthetic protein FliP ACN91_19525 ENOG4105DD5 Flagellar motor switch protein ACN91_19530 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ACN91_19540 ENOG4105E4C Lytic transglycosylase catalytic ACN91_19545 ENOG4105I03 Flagellin ACN91_19550 ENOG4105I03 Flagellin ACN91_19555 ENOG4105I03 Flagellin ACN91_19570 ENOG4107R88 Chemotaxis protein (CheV) ACN91_19585 ENOG4105BZE flagellar hook protein, FlgE ACN91_19615 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) ACN91_19620 ENOG4107U2N Flagellar M-ring protein ACN91_19625 ENOG41075Z6 flagellar hook-basal body complex protein fliE ACN91_19630 ENOG4108ZC9 flagellar basal-body rod protein flgc ACN91_19635 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) ACN91_19650 ENOG4107TPX flagellar hook-associated ACN91_19655 ENOG4105DTJ flagellar hook-associated protein ACN91_19660 ENOG4105E1Q flagellar hook-associated protein ACN91_19680 ENOG4105BZU Histidine kinase ACN91_19695 ENOG4105DD5 Flagellar motor switch protein ACN91_19700 ENOG4105CBS Chea signal transduction histidine kinase ACN91_19705 ENOG4107YTP response regulator receiver protein ACN91_19710 ENOG4105ER2 Ompa motb domain protein ACN91_19715 ENOG4107R0U MotA TolQ exbB proton channel ACN91_19725 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) ACN91_19775 ENOG41080C8 DUF218 domain ACN91_19780 ENOG4105H67 Protein of unknown function (DUF421) ACN91_19790 ENOG4108Z5V transcriptional regulator, merr family ACN91_19795 ENOG4107RWR Sodium hydrogen exchanger ACN91_19805 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) ACN91_19870 ENOG41081VK Ribonuclease ACN91_19890 ENOG4108SZE gCN5-related N-acetyltransferase ACN91_19905 ENOG4105CPK Glycosyl transferase (Group 1 ACN91_19935 ENOG4105HTX biosynthesis protein ACN91_19980 ENOG4105KHC sulfurtransferase ACN91_19990 ENOG4108W0I acetyltransferase ACN91_20000 ENOG410890F Dynamin family ACN91_20005 ENOG4105DHF Membrane ACN91_20010 ENOG4105C2W permease ACN91_20020 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ACN91_20030 ENOG4105CTD carboxy-peptidase ACN91_20035 ENOG4105DVT helicase ACN91_20070 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) ACN91_20080 ENOG4106F55 Protein of unknown function (DUF1273) ACN91_20120 ENOG4105BZ4 penicillin-binding protein ACN91_20130 ENOG4105CSM endonuclease III ACN91_20150 ENOG4105YAC ACN91_20155 ENOG4105DVT helicase ACN91_20170 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) ACN91_20195 ENOG4105CPK Glycosyl transferase (Group 1 ACN91_20200 ENOG4105FJR Lmbe family ACN91_20215 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase ACN91_20220 ENOG4108JYZ YitT family ACN91_20255 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) ACN91_20260 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) ACN91_20275 ENOG41068YB TPR repeat-containing protein ACN91_20290 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase ACN91_20295 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) ACN91_20300 ENOG4105EAH synthase ACN91_20310 ENOG4105XXQ heptaprenyl diphosphate synthase component I ACN91_20325 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) ACN91_20355 ENOG41065D1 ACN91_20360 ENOG4105S2F ACN91_20395 ENOG4107RB3 L-asparaginase ACN91_20400 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase ACN91_20425 ENOG4108S6Z Negative regulator of genetic competence ACN91_20430 ENOG4108XDN Transcriptional regulator ACN91_20435 ENOG4107RGJ metallophosphoesterase ACN91_20445 ENOG4105I7S Abortive infection protein ACN91_20450 ENOG4105C9U ATP-dependent DNA helicase RecQ ACN91_20465 ENOG4108SAX Membrane ACN91_20480 ENOG4108WBT adenosyltransferase ACN91_20485 ENOG4105BZU Histidine kinase ACN91_20490 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_20495 ENOG4105CRE cytochrome C ACN91_20500 ENOG4107TWT Cytochrome c biogenesis protein ACN91_20505 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ACN91_20510 ENOG4105FE9 pseudouridine synthase ACN91_20520 ENOG4108JIC nucleoside recognition domain protein ACN91_20525 ENOG4105DZ1 carboxypeptidase ACN91_20530 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) ACN91_20560 ENOG4105BZU Histidine kinase ACN91_20575 ENOG4105I3N Conserved Protein ACN91_20580 ENOG4105BZU Histidine kinase ACN91_20595 ENOG4105BZ4 penicillin-binding protein ACN91_20600 ENOG4107GRR phosphate transport regulator ACN91_20605 ENOG4105CJ3 phosphate transporter ACN91_20630 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) ACN91_20655 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) ACN91_20675 ENOG4105WH1 Two component transcriptional regulator luxr family ACN91_20680 ENOG4105ENE Histidine kinase ACN91_20700 ENOG4105DFD Na H antiporter ACN91_20720 ENOG4105C8J )-transporter ACN91_20730 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein ACN91_20735 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein ACN91_20740 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) ACN91_20750 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) ACN91_20755 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) ACN91_20775 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) ACN91_20785 ENOG4105E0M Sulfatase ACN91_20790 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase ACN91_20805 ENOG4107RVV histidinol phosphate phosphatase, hisj family ACN91_20830 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) ACN91_20835 ENOG4105ECC imidazole-glycerol-phosphate dehydratase ACN91_20840 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) ACN91_20860 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) ACN91_20875 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase ACN91_20880 ENOG4108ZP8 Acetolactate synthase small subunit ACN91_20885 ENOG4105C7K acetolactate synthase ACN91_20890 ENOG4105CM2 brancheD-chain amino acid aminotransferase ACN91_20920 ENOG4105KBJ sporulation protein ytfj ACN91_20925 ENOG41063Y9 ACN91_20930 ENOG4105CZN Potassium uptake protein ACN91_20960 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) ACN91_21000 ENOG4105NQC Flavodoxin ACN91_21025 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein ACN91_21035 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD ACN91_21040 ENOG4105EA8 2-Nitropropane dioxygenase ACN91_21045 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A ACN91_21085 ENOG4105CJ1 ABC, transporter ACN91_21095 ENOG4105CZV ABC transporter ACN91_21100 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family ACN91_21105 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ACN91_21110 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) ACN91_21115 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) ACN91_21165 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) ACN91_21170 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase ACN91_21175 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) ACN91_21180 ENOG4105BZU Histidine kinase ACN91_21190 ENOG4106DF1 ACN91_21200 ENOG41090MY MarR family Transcriptional regulator ACN91_21205 ENOG4105BZU Histidine kinase ACN91_21215 ENOG4105PXI polysaccharide deacetylase ACN91_21225 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) ACN91_21240 ENOG4105E98 transcriptional regulator DeoR family ACN91_21260 ENOG4107RCV ABC transporter, permease ACN91_21265 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ACN91_21270 ENOG4105C4Y ABC transporter ACN91_21300 ENOG4105CHR reductase ACN91_21320 ENOG4108Z7G MaoC domain protein dehydratase ACN91_21325 ENOG410681C small acid-soluble spore protein ACN91_21330 ENOG4105CZN Potassium uptake protein ACN91_21335 ENOG4107TS3 membrane protein, TerC ACN91_21340 ENOG4108QTI )-transporter ACN91_21350 ENOG4106A3R peptidase ACN91_21370 ENOG4105JXH GntR family transcriptional regulator ACN91_21375 ENOG4105BZU Histidine kinase ACN91_21380 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_21395 ENOG4105CQB FAD linked oxidase domain protein ACN91_21400 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) ACN91_21405 ENOG4105K4I Scp-like extracellular ACN91_21415 ENOG4108YBP pseudouridine synthase ACN91_21425 ENOG4105EYF MMPL domain protein ACN91_21435 ENOG4107RUE extracellular solute-binding protein family 1 ACN91_21440 ENOG4105D38 putrescine abc transporter ACN91_21445 ENOG4105F38 ABC transporter, permease ACN91_21450 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ACN91_21455 ENOG4105C26 Dehydrogenase ACN91_21490 ENOG4105VFR signal peptidase ACN91_21495 ENOG4105DZ1 carboxypeptidase ACN91_21525 ENOG4108HE4 integrase family ACN91_21530 ENOG4108NE4 ACN91_21645 ENOG4105VZ8 Transcriptional regulator ACN91_21650 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 ACN91_21655 ENOG4105C7S Dehydrogenase ACN91_21675 ENOG41089UC methyltransferase, type 11 ACN91_21740 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) ACN91_21750 ENOG4105DK0 Indole-3-glycerol phosphate synthase ACN91_21755 ENOG4108I0Q anthranilate phosphoribosyltransferase ACN91_21760 ENOG4105DDQ anthranilate synthase ACN91_21765 ENOG4105CRQ synthase (Component I) ACN91_21775 ENOG4105CK7 Sodium proline symporter ACN91_21850 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase ACN91_21860 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase ACN91_21865 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) ACN91_21885 ENOG4107TVC Glycosyl transferase, family 2 ACN91_21905 ENOG4105K64 Glycosyl transferase, family 2 ACN91_21925 ENOG4105EMS pseudouridine synthase ACN91_21930 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) ACN91_21940 ENOG4106EFP UPF0738 protein ACN91_21945 ENOG4105MIX Adenylate cyclase ACN91_21950 ENOG4108Z18 K06886 hemoglobin ACN91_21965 ENOG4105DPN Oligoendopeptidase f ACN91_21975 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ACN91_21985 ENOG4108ZCF integral membrane protein ACN91_22010 ENOG4105UQX Mate efflux family protein ACN91_22015 ENOG4108JQ7 (ABC) transporter ACN91_22025 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ACN91_22030 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ACN91_22045 ENOG4105C31 Tryptophanyl-tRNA synthetase ACN91_22060 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) ACN91_22065 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) ACN91_22090 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit ACN91_22105 ENOG4108KP7 hydrolase ACN91_22115 ENOG41073B9 ACN91_22120 ENOG4107AYK membrAne ACN91_22130 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ACN91_22155 ENOG4105CNA YD repeat protein ACN91_22160 ENOG4105QNR S1 RNA binding domain protein ACN91_22180 ENOG4105BZU Histidine kinase ACN91_22185 ENOG4105CH6 catalase ACN91_22190 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) ACN91_22195 ENOG4105CAQ asparagine synthetase ACN91_22205 ENOG4106BKT UPF0344 protein ACN91_22210 ENOG4105C8Y Acetylornithine aminotransferase ACN91_22220 ENOG4105ERH Fumarylacetoacetate hydrolase ACN91_22260 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ACN91_22265 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation ACN91_22300 ENOG4105VEQ Cold shock protein ACN91_22320 ENOG4107QP3 malate synthase g ACN91_22330 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) ACN91_22335 ENOG4105C8Q Methyl-accepting chemotaxis ACN91_22340 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 ACN91_22365 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_22380 ENOG41086D8 Transcriptional regulator ACN91_22385 ENOG4108AEY RNA polymerase sigma factor ACN91_22415 ENOG4108JJB ABC transporter ACN91_22420 ENOG4107TVP HD domain protein ACN91_22430 ENOG4107RN3 metallophosphoesterase ACN91_22440 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) ACN91_22445 ENOG4108IJ6 ABC transporter ACN91_22450 ENOG4105ECW sulfate abc transporter ACN91_22455 ENOG4108I5D sulfate abc transporter ACN91_22460 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein ACN91_22470 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_22480 ENOG4105DF9 Lipoate-protein, ligase ACN91_22485 ENOG4108RQ5 Beta-lactamase domain-containing protein ACN91_22490 ENOG4106AXD ACN91_22520 ENOG4105ECB domain protein ACN91_22535 ENOG4105NA0 Transcriptional regulator ACN91_22560 ENOG4105C1Q protoporphyrinogen oxidase ACN91_22565 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) ACN91_22575 ENOG4105BZ4 penicillin-binding protein ACN91_22580 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation ACN91_22585 ENOG4105CKV Membrane ACN91_22590 ENOG410905X membrane-flanked domain protein ACN91_22640 ENOG4105CKV Membrane ACN91_22645 ENOG410905X membrane-flanked domain protein ACN91_22675 ENOG4105K59 histidine triad (HIT) protein ACN91_22705 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) ACN91_22715 ENOG4105EEM helicase ACN91_22725 ENOG4105CNI cell division protein FtsW ACN91_22735 ENOG4105EMN RNA polymerase sigma factor ACN91_22745 ENOG4105C6V Glycerol-3-phosphate dehydrogenase ACN91_22760 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator ACN91_22765 ENOG4105D7V transposase ACN91_22770 ENOG41067QW Transcriptional regulator ACN91_22775 ENOG4105F0F Oxalate decarboxylase ACN91_22790 ENOG4108MUZ hydrolase ACN91_22815 ENOG410829K Lysine exporter protein (Lyse ygga) ACN91_22830 ENOG4106D4I domain protein ACN91_22835 ENOG4107VRP DNA repair exonuclease ACN91_22855 ENOG4107QHE Choloylglycine hydrolase ACN91_22895 ENOG4105BZU Histidine kinase ACN91_22900 ENOG4105BZU Histidine kinase ACN91_22905 ENOG4108MJI response regulator ACN91_22915 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) ACN91_22925 ENOG4105WN5 stage II sporulation protein ACN91_22965 ENOG4108WC5 Alpha Beta Hydrolase Fold protein ACN91_23030 ENOG4105CMT Dihydroxyacetone kinase ACN91_23040 ENOG4105CMT Dihydroxyacetone kinase ACN91_23055 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase ACN91_23100 ENOG4105F6J Alpha beta hydrolase fold ACN91_23125 ENOG4105D9U N-acetyltransferase ACN91_23135 ENOG4105C0R drug resistance transporter emrb qaca subfamily ACN91_23165 ENOG4105CDU Replicative dna helicase ACN91_23200 ENOG4105CFI type iii restriction protein res subunit ACN91_23215 ENOG4105M6F mutator MutT protein ACN91_23225 ENOG4108MRH transcriptional regulatory protein ACN91_23235 ENOG4105CSH Transporter ACN91_23260 ENOG4108JQ7 (ABC) transporter ACN91_23270 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ACN91_23290 ENOG4105CIF Ornithine Cyclodeaminase ACN91_23295 ENOG4105CTU Proline racemase ACN91_23315 ENOG4105DER m42 family ACN91_23335 ENOG4105CGU Enoyl-CoA hydratase ACN91_23360 ENOG4105CHH sulfate transporter ACN91_23375 ENOG4105CEY Amp-dependent synthetase and ligase ACN91_23380 ENOG4105D4P Coproporphyrinogen iii oxidase ACN91_23385 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase ACN91_23400 ENOG4108VX5 3-methyladenine DNA glycosylase ACN91_23405 ENOG4107FQX Alpha-acetolactate decarboxylase ACN91_23435 ENOG4108UH6 UPF0754 membrane protein ACN91_23445 ENOG410839P ACN91_23460 ENOG4105CDA abc transporter atp-binding protein ACN91_23465 ENOG4105DRP amino acid AbC transporter ACN91_23475 ENOG4105BZ1 (ABC) transporter ACN91_23480 ENOG4105BZ1 (ABC) transporter ACN91_23490 ENOG4105C26 Dehydrogenase ACN91_23500 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) ACN91_23505 ENOG4105D5Q Arginine ornithine antiporter ACN91_23515 ENOG4107RKG DJ-1/PfpI family ACN91_23525 ENOG4105E5W Transporter ACN91_23530 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) ACN91_23540 ENOG4105NF4 modulator of drug activity ACN91_23570 ENOG4105KPY Small multidrug resistance protein ACN91_23580 ENOG4108IXY short-chain dehydrogenase reductase ACN91_23585 ENOG4105CH7 arginosuccinase ACN91_23590 ENOG4108YXU transcriptional regulator AsnC family ACN91_23625 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate ACN91_23630 ENOG4106KNT transcriptional regulator ACN91_23640 ENOG4107RWR Sodium hydrogen exchanger ACN91_23645 ENOG4105CUB amino acid ACN91_23680 ENOG4107T5V SNARE associated Golgi ACN91_23715 ENOG4105WEF catalase ACN91_23750 ENOG4105C19 ABC transporter ACN91_23755 ENOG4107RBB ABC transporter, permease ACN91_23760 ENOG41069ER domain protein ACN91_23780 ENOG4105VZJ PTS System ACN91_23785 ENOG4105VCP PTS System ACN91_23790 ENOG4105EMD TRANSCRIPTIONal ACN91_23815 ENOG4108KGH TRANSCRIPTIONal ACN91_23825 ENOG41087NI Sulfite exporter TauE/SafE ACN91_23830 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase ACN91_23845 ENOG4105VFE sira family ACN91_23850 ENOG4107TPS domain protein ACN91_23855 ENOG4105VFE sira family ACN91_23860 ENOG4105XTG Pfam:DUF156 ACN91_23865 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase ACN91_23870 ENOG4108TCS Glutamyl endopeptidase ACN91_23880 ENOG4105ED1 spovr family ACN91_23885 ENOG4107Y03 Nitroreductase ACN91_23905 ENOG4108B31 Spore germination protein ACN91_23925 ENOG4105K63 Thioredoxin ACN91_23940 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein ACN91_23950 ENOG4105C7N Xanthine uracil vitamin C permease ACN91_23960 ENOG4105C2J ABC transporter ACN91_23965 ENOG4105CNN ABC, transporter ACN91_23975 ENOG4105C19 ABC transporter ACN91_24000 ENOG4108INS Transcriptional regulator ACN91_24015 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) ACN91_24050 ENOG4105DWF phosphomethylpyrimidine kinase ACN91_24055 ENOG4105D06 uba thif-type nad fad binding protein ACN91_24070 ENOG41080HI glycine oxidase ACN91_24075 ENOG4108VEU Thiamine monophosphate synthase ACN91_24085 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ACN91_24095 ENOG4105ETU transcriptional activator (TenA ACN91_24120 ENOG41080XQ Signal transduction protein with cbs domains ACN91_24260 ENOG4105E2Z phosphate ABC transporter (Permease ACN91_24265 ENOG4105C8U phosphate abc transporter ACN91_24270 ENOG4105CVA phosphate ACN91_24275 ENOG4105CE1 Ferrous iron transport protein b ACN91_24280 ENOG4105CE1 Ferrous iron transport protein b ACN91_24285 ENOG4105CE1 Ferrous iron transport protein b ACN91_24295 ENOG4108NHD germination protein ACN91_24310 ENOG4105E1V na solute symporter ACN91_24315 ENOG4106CAD Protein of unknown function (DUF3311) ACN91_24335 ENOG4105E2S oxidase) subunit II ACN91_24340 ENOG4105BZ9 Cytochrome C oxidase, subunit I ACN91_24365 ENOG4105MA6 gCN5-related N-acetyltransferase ACN91_24380 ENOG4105C7N Xanthine uracil vitamin C permease ACN91_24385 ENOG4105C85 amino acid ACN91_24405 ENOG4105DUX Transporter ACN91_24420 ENOG4107D63 ACN91_24425 ENOG4105VZ8 Transcriptional regulator ACN91_24430 ENOG41069ER domain protein ACN91_24435 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer ACN91_24440 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) ACN91_24470 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) ACN91_24510 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) ACN91_24515 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator ACN91_24520 ENOG4105CNN ABC, transporter ACN91_24525 ENOG4105C2J ABC transporter ACN91_24535 ENOG4108RVA ribokinase ACN91_24540 ENOG4105ETE Transcriptional regulator (LacI family ACN91_24545 ENOG4105C0R drug resistance transporter emrb qaca subfamily ACN91_24550 ENOG41067TZ transcriptional regulator, MarR family ACN91_24555 ENOG4105CXY transporter ACN91_24565 ENOG4108JQ7 (ABC) transporter ACN91_24570 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ACN91_24580 ENOG4105DEF Extracellular solute-binding protein, family 5 ACN91_24590 ENOG4107YZX Universal stress protein ACN91_24595 ENOG4105CHH sulfate transporter ACN91_24610 ENOG4105BZU Histidine kinase ACN91_24615 ENOG4105NAE bifunctional deaminase-reductase domain protein ACN91_24620 ENOG4105D29 Helix-turn-helix type 11 domain protein ACN91_24635 ENOG4108IQI permease ACN91_24640 ENOG4105DRP amino acid AbC transporter ACN91_24645 ENOG4105EAD ABC transporter ACN91_24650 ENOG4105CT1 (ABC) transporter ACN91_24655 ENOG4105CDA abc transporter atp-binding protein ACN91_24660 ENOG4105BZG amino acid carrier protein ACN91_24665 ENOG4105CRN Aminoglycoside phosphotransferase ACN91_24670 ENOG4105E1K spore germination protein ACN91_24685 ENOG4105CG3 alpha amylase, catalytic region ACN91_24690 ENOG4105C5Y PTS System ACN91_24695 ENOG4107414 GntR family transcriptional regulator ACN91_24700 ENOG4105D5Q Arginine ornithine antiporter ACN91_24705 ENOG4105BZU Histidine kinase ACN91_24715 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) ACN91_24720 ENOG4105GMT ATPase associated with various cellular activities aaa_5 ACN91_24725 ENOG4107T89 von Willebrand factor, type A ACN91_24735 ENOG4105EXW epimerase dehydratase ACN91_24750 ENOG4105E0A ABC, transporter ACN91_24755 ENOG4108IHU transport system permease protein ACN91_24760 ENOG4105DQ5 transport system permease protein ACN91_24765 ENOG4108MES Periplasmic binding protein ACN91_24770 ENOG4105DUX Transporter ACN91_24785 ENOG4105DAA L-lactate ACN91_24790 ENOG4108IJ0 Aspartate ammonia-lyase ACN91_24795 ENOG4105C37 (CBS) domain ACN91_24800 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase ACN91_24805 ENOG4105D9N nucleoside ACN91_24810 ENOG4108KGH TRANSCRIPTIONal ACN91_24815 ENOG41073R8 VanW family ACN91_24845 ENOG4105DAP Nicotinate phosphoribosyltransferase ACN91_24850 ENOG4105C59 p-type ATPase ACN91_24860 ENOG4105CUB amino acid ACN91_24880 ENOG4108JB9 formate dehydrogenase ACN91_24885 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) ACN91_24900 ENOG4105CK6 Two component transcriptional regulator (Winged helix family ACN91_24905 ENOG4105BZU Histidine kinase ACN91_24915 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family ACN91_24920 ENOG4108UZ3 Transporter ACN91_24930 ENOG4105C6K Malic enzyme ACN91_24940 ENOG4108MRH transcriptional regulatory protein ACN91_24965 ENOG4105US7 Histidine kinase ACN91_24970 ENOG4108STX response regulator ACN91_24975 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) ACN91_24980 ENOG4105BZ7 extracellular solute-binding protein family 1 ACN91_24985 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component ACN91_24990 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component ACN91_24995 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) ACN91_25000 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator ACN91_25025 ENOG4105D4T Citrate transporter ACN91_25030 ENOG4108V9W transcriptional regulatory protein ACN91_25035 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism ACN91_25045 ENOG4105DZ6 Band 7 protein ACN91_25060 ENOG4105C94 Transporter ACN91_25095 ENOG41062ES Transcriptional regulator ACN91_25100 ENOG4105C57 major facilitator superfamily ACN91_25120 ENOG4105CYN Serine protein kinase ACN91_25135 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) ACN91_25145 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) ACN91_25155 ENOG4108R9S DSBA oxidoreductase ACN91_25160 ENOG4108JQC penicillin-binding protein 1A ACN91_25290 ENOG4105G5W regulator Fur family ACN91_25295 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ACN91_25315 ENOG4108IUW ABC transporter ACN91_25325 ENOG4105CBC glutamate synthase ACN91_25330 ENOG4107NBY Membrane ACN91_25335 ENOG4105BZ1 (ABC) transporter ACN91_25355 ENOG4106BXE ACN91_25360 ENOG4105CEN a g-specific adenine glycosylase ACN91_25365 ENOG41067AE Membrane-bound metal-dependent hydrolase ACN91_25395 ENOG4105ECP epimerase ACN91_25400 ENOG4105CI2 imidazolone-5-propionate hydrolase ACN91_25420 ENOG4105F1A Pyruvate formate-lyase ACN91_25435 ENOG4105CKK Glycosyl transferase, family 2 ACN91_25440 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) ACN91_25445 ENOG4107QQG Dehydrogenase ACN91_25450 ENOG4107R51 Glycosyl transferase, family 2 ACN91_25465 ENOG4108A04 Beta-lactamase ACN91_25505 ENOG4108IQI permease ACN91_25515 ENOG4108JUB Transcriptional regulator ACN91_25525 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) ACN91_25530 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ACN91_25565 ENOG4105UPD Calcium Proton ACN91_25570 ENOG410606W general stress protein ACN91_25585 ENOG4107ZTW SNARE associated Golgi ACN91_25605 ENOG4108IPJ Membrane ACN91_25610 ENOG4105C59 p-type ATPase ACN91_25615 ENOG4107U9T Pfam:Ribonuclease_BN ACN91_25625 ENOG4105KJF protein tyrosine phosphatase ACN91_25630 ENOG41068PA UPF0435 protein ACN91_25645 ENOG4108TTB tellurium resistance protein ACN91_25650 ENOG4107TS3 membrane protein, TerC ACN91_25655 ENOG4106FN3 tellurium resistance protein ACN91_25660 ENOG4106FN3 tellurium resistance protein ACN91_25665 ENOG4108N0M stress protein ACN91_25680 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) ACN91_25695 ENOG4105DEU major facilitator superfamily ACN91_25710 ENOG41062JF Transcriptional regulator ACN91_25740 ENOG4105C5H ABC transporter ACN91_25750 ENOG4105D2X ABC transporter substrate-binding protein ACN91_25755 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component ACN91_25775 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter ACN91_25790 ENOG4105C9U ATP-dependent DNA helicase RecQ ACN91_25805 ENOG4105CI1 PTS System ACN91_25815 ENOG4105DNP FAD linked oxidase domain protein ACN91_25825 ENOG4108W63 CRP FNR family transcriptional regulator ACN91_25830 ENOG4105C5B carbamate kinase ACN91_25840 ENOG4105DBV ornithine carbamoyltransferase ACN91_25855 ENOG4105C8Q Methyl-accepting chemotaxis ACN91_25860 ENOG4105CDA abc transporter atp-binding protein ACN91_25865 ENOG4105EAB amino acid AbC transporter ACN91_25870 ENOG4105E5Q amino acid AbC transporter ACN91_25885 ENOG4105D2S major facilitator superfamily ACN91_25890 ENOG410756H nucleotidyltransferase ACN91_25910 ENOG4105BZU Histidine kinase ACN91_25925 ENOG4106UIA ACN91_25930 ENOG4106UIA ACN91_25950 ENOG4105CAY ferredoxin--nadp reductase ACN91_25960 ENOG4108V5C ABC transporter ACN91_25965 ENOG4105DQ5 transport system permease protein ACN91_25970 ENOG4105EHG Permease protein ACN91_25975 ENOG4107W7X Aldolase ACN91_25980 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) ACN91_25985 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) ACN91_25990 ENOG4105D3R alkyl hydroperoxide reductase ACN91_26010 ENOG4105DFD Na H antiporter ACN91_26020 ENOG4105DTQ mandelate racemase muconate lactonizing ACN91_26035 ENOG4108W15 Protein of unknown function (DUF1456) ACN91_26045 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) ACN91_26050 ENOG4105D9N nucleoside ACN91_26075 ENOG4105KPY Small multidrug resistance protein ACN91_26080 ENOG4105C26 Dehydrogenase ACN91_26090 ENOG4108JPW Aminotransferase ACN91_26100 ENOG4105CBD Diacylglycerol kinase ACN91_26120 ENOG4107I77 yiaA/B two helix domain ACN91_26125 ENOG4105D01 (LipO)protein ACN91_26130 ENOG4108UMI ABC transporter, permease ACN91_26135 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ACN91_26145 ENOG4108W2Y isochorismatase ACN91_26170 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) ACN91_26175 ENOG4105C4R Atp-dependent dna helicase ACN91_26200 ENOG4105EGI Transcriptional regulator ACN91_26210 ENOG4105C12 Phosphoribosylglycinamide synthetase ACN91_26220 ENOG4108V3E phosphoribosylglycinamide formyltransferase ACN91_26245 ENOG4105VR9 phosphoribosylformylglycinamidine synthase ACN91_26255 ENOG4105C83 adenylosuccinate lyase ACN91_26260 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit ACN91_26265 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) ACN91_26295 ENOG4105BZU Histidine kinase ACN91_26305 ENOG4105C7N Xanthine uracil vitamin C permease ACN91_26325 ENOG4108TYN CAAX amino terminal protease family protein ACN91_26340 ENOG4105C5H ABC transporter ACN91_26345 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) ACN91_26350 ENOG410801F ribosomal-protein-alanine acetyltransferase ACN91_26355 ENOG41072GX Peptidase M22 Glycoprotease ACN91_26360 ENOG4105K8N protein family UPF0079, ATPase ACN91_26475 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) ACN91_26485 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) ACN91_26490 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein ACN91_26515 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) ACN91_26520 ENOG4105CPF Cell wall formation (By similarity) ACN91_26525 ENOG4108SC4 )-transporter ACN91_26530 ENOG4105CUB amino acid ACN91_26540 ENOG4105ERH Fumarylacetoacetate hydrolase ACN91_26545 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase ACN91_26570 ENOG410667J hydrolase ACN91_26575 ENOG4108JQ7 (ABC) transporter ACN91_26580 ENOG4105C3U ABC transporter ACN91_26585 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ACN91_26595 ENOG4105DEF Extracellular solute-binding protein, family 5 ACN91_26605 ENOG4105C5H ABC transporter ACN91_26630 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) ACN91_26650 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) ACN91_26670 ENOG4105F6E Acyl-transferase ACN91_26690 ENOG4105EGI Transcriptional regulator ACN91_26705 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family ACN91_26710 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein ACN91_26715 ENOG4105E0C molybdate abc transporter ACN91_26725 ENOG4106Z1T Nicotinamide Mononucleotide Transporter ACN91_26745 ENOG4108J59 Extracellular solute-binding protein, family 5 ACN91_26750 ENOG4108J59 Extracellular solute-binding protein, family 5 ACN91_26770 ENOG4108JQ7 (ABC) transporter ACN91_26775 ENOG4105C3U ABC transporter ACN91_26780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component ACN91_26785 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component ACN91_26805 ENOG4105C2C drug resistance transporter, Bcr CflA ACN91_26820 ENOG4105IQ5 FAD linked oxidase domain protein ACN91_26830 ENOG4105CB2 alcohol dehydrogenase ACN91_26835 ENOG4105D01 (LipO)protein ACN91_26840 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) ACN91_26845 ENOG4108UMI ABC transporter, permease ACN91_26850 ENOG4108PSK reductase ACN91_26870 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein ACN91_26875 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) ACN91_26890 ENOG4107U5W ybbr family ACN91_26895 ENOG4105C8B TIGR00159 family ACN91_26985 ENOG4108NMV polysaccharide deacetylase ACN91_27000 ENOG4105D1F ATP-binding protein ACN91_27025 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) ACN91_27030 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) ACN91_27035 ENOG4108JJB ABC transporter ACN91_27040 ENOG4108JJB ABC transporter ACN91_27065 ENOG41067V7 50S ribosomal protein L36 ACN91_27075 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) ACN91_27085 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) ACN91_27110 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) ACN91_27215 ENOG4105XPM ribosomal protein ACN91_27220 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) ACN91_27230 ENOG4107Y49 methyltransferase ACN91_27235 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) ACN91_27255 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) ACN91_27270 ENOG4105QIV RNA polymerase ACN91_27275 ENOG4105M0M Tetracycline resistance protein ACN91_27280 ENOG4105C2N RNA methyltransferase TrmH family group 3 ACN91_27295 ENOG4105D7W serine acetyltransferase ACN91_27315 ENOG4105CTP PilT protein domain protein ACN91_27325 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) ACN91_27340 ENOG4108Z0C Uvrb UvrC protein ACN91_27380 ENOG4105SX7 Transporter ACN91_27390 ENOG4105SX7 Transporter ACN91_27405 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) ACN91_27455 ENOG4105DPZ Two component transcriptional regulator (Winged helix family ACN91_27520 ENOG4108RDQ ABC transporter ACN91_27555 ENOG4105RHY Pfam:UPF0157 ACN91_27615 ENOG4105DA5 (ABC) transporter