locus-tag	class	description
PFY08_00010	COG0592	DNA-directed DNA polymerase activity
PFY08_00015	COG2501	S4 domain
PFY08_00025	COG0187	DNA topoisomerase II activity
PFY08_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFY08_00065	COG0516	GMP reductase activity
PFY08_00065	COG0517	IMP dehydrogenase activity
PFY08_00070	COG1686	Belongs to the peptidase S11 family
PFY08_00100	COG1428	Deoxynucleoside kinase
PFY08_00105	COG1428	Deoxynucleoside kinase
PFY08_00110	COG1335	isochorismatase
PFY08_00115	COG0590	tRNA wobble adenosine to inosine editing
PFY08_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFY08_00180	COG1982	Orn Lys Arg decarboxylase major
PFY08_00190	COG0470	DNA polymerase III
PFY08_00195	COG1774	PSP1 C-terminal conserved region
PFY08_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PFY08_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PFY08_00220	COG2002	toxin-antitoxin pair type II binding
PFY08_00230	COG0084	hydrolase, TatD family'
PFY08_00250	COG4466	Protein conserved in bacteria
PFY08_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PFY08_00270	COG0251	oxidation-reduction process
PFY08_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PFY08_00305	COG2002	toxin-antitoxin pair type II binding
PFY08_00310	COG2244	polysaccharide biosynthetic process
PFY08_00315	COG3956	TIGRFAM MazG family protein
PFY08_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PFY08_00340	COG1098	S1 RNA binding domain
PFY08_00355	COG2208	phosphoserine phosphatase activity
PFY08_00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFY08_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PFY08_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PFY08_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PFY08_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
PFY08_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PFY08_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PFY08_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PFY08_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PFY08_00420	COG1396	sequence-specific DNA binding
PFY08_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFY08_00515	COG3880	PFAM UvrB UvrC protein
PFY08_00525	COG0542	response to heat
PFY08_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PFY08_00560	COG1045	serine acetyltransferase
PFY08_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFY08_00580	COG3688	RNA-binding protein containing a PIN domain
PFY08_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PFY08_00600	COG0250	Participates in transcription elongation, termination and antitermination
PFY08_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PFY08_00625	COG2813	Specifically methylates the guanine in position
PFY08_00640	COG1358	cellular component organization or biogenesis
PFY08_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PFY08_00710	COG0255	Belongs to the universal ribosomal protein uL29 family
PFY08_00770	COG0201	protein transport
PFY08_00780	COG0024	Methionine aminopeptidase
PFY08_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PFY08_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFY08_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
PFY08_00855	COG0489	protein tyrosine kinase activity
PFY08_00865	COG2194	sulfuric ester hydrolase activity
PFY08_00870	COG0726	polysaccharide deacetylase
PFY08_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFY08_00955	COG4856	YbbR-like protein
PFY08_00995	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_01000	COG2011	ABC-type metal ion transport system permease component
PFY08_01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PFY08_01010	COG1464	Belongs to the NlpA lipoprotein family
PFY08_01015	COG0604	alcohol dehydrogenase
PFY08_01025	COG0277	FAD linked oxidase domain protein
PFY08_01030	COG2271	Major facilitator Superfamily
PFY08_01040	COG2814	Major facilitator Superfamily
PFY08_01060	COG0601	transmembrane transport
PFY08_01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFY08_01070	COG0444	Belongs to the ABC transporter superfamily
PFY08_01075	COG4608	Belongs to the ABC transporter superfamily
PFY08_01080	COG4166	transmembrane transport
PFY08_01090	COG2207	Transcriptional regulator
PFY08_01105	COG4166	transmembrane transport
PFY08_01110	COG4166	transmembrane transport
PFY08_01115	COG0656	L-ascorbic acid biosynthetic process
PFY08_01135	COG4149	molybdate abc transporter
PFY08_01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
PFY08_01145	COG1910	domain protein
PFY08_01160	COG0697	spore germination
PFY08_01175	COG0204	Acyl-transferase
PFY08_01185	COG1609	Transcriptional regulator
PFY08_01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_01210	COG5298	Protein conserved in bacteria
PFY08_01235	COG0488	(ABC) transporter
PFY08_01245	COG0747	negative chemotaxis
PFY08_01250	COG0601	transmembrane transport
PFY08_01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFY08_01260	COG0444	Belongs to the ABC transporter superfamily
PFY08_01265	COG4608	Belongs to the ABC transporter superfamily
PFY08_01270	COG0561	phosphatase activity
PFY08_01300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PFY08_01305	COG0179	Fumarylacetoacetate (FAA) hydrolase
PFY08_01315	COG0531	amino acid
PFY08_01320	COG2814	Major facilitator Superfamily
PFY08_01330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PFY08_01340	COG4294	response to UV
PFY08_01345	COG0705	Rhomboid family
PFY08_01355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PFY08_01360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFY08_01365	COG0864	Transcriptional regulator
PFY08_01370	COG2337	Toxic component of a toxin-antitoxin (TA) module
PFY08_01375	COG2183	response to ionizing radiation
PFY08_01475	COG0802	atpase or kinase
PFY08_01480	COG1214	PFAM Peptidase M22, glycoprotease
PFY08_01485	COG0456	acetyltransferase
PFY08_01495	COG0488	(ABC) transporter
PFY08_01510	COG1266	CAAX protease self-immunity
PFY08_01530	COG2252	PERMEase
PFY08_01540	COG5002	protein histidine kinase activity
PFY08_01565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PFY08_01605	COG2205	protein histidine kinase activity
PFY08_01610	COG0745	RESPONSE REGULATOR receiver
PFY08_01640	COG2226	methyltransferase
PFY08_01650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PFY08_01660	COG1215	transferase activity, transferring glycosyl groups
PFY08_01680	COG0697	spore germination
PFY08_01710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PFY08_01715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PFY08_01720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PFY08_01730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFY08_01745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PFY08_01755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PFY08_01765	COG0151	Belongs to the GarS family
PFY08_01790	COG0210	DNA helicase
PFY08_01800	COG4851	CamS sex pheromone cAM373 precursor
PFY08_01815	COG1335	isochorismatase
PFY08_01825	COG2011	ABC-type metal ion transport system permease component
PFY08_01830	COG1464	Belongs to the NlpA lipoprotein family
PFY08_01845	COG0003	Pfam Anion-transporting ATPase
PFY08_01850	COG1846	Transcriptional regulator
PFY08_01855	COG4682	membrane
PFY08_01875	COG1597	lipid kinase activity
PFY08_01885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFY08_01895	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_01900	COG2076	Multidrug Resistance protein
PFY08_01910	COG2309	aminopeptidase activity
PFY08_01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFY08_01945	COG4807	Protein conserved in bacteria
PFY08_01970	COG1757	Na H antiporter
PFY08_01975	COG1473	amidohydrolase
PFY08_01990	COG0450	alkyl hydroperoxide reductase
PFY08_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_02020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_02025	COG0492	ferredoxin-NADP+ reductase activity
PFY08_02035	COG0166	Belongs to the GPI family
PFY08_02060	COG5002	protein histidine kinase activity
PFY08_02080	COG3541	Predicted nucleotidyltransferase
PFY08_02085	COG2814	Major facilitator Superfamily
PFY08_02090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PFY08_02090	COG0723	plastoquinol--plastocyanin reductase activity
PFY08_02100	COG0765	amino acid transport
PFY08_02105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PFY08_02110	COG1126	abc transporter atp-binding protein
PFY08_02115	COG0840	transmembrane signaling receptor activity
PFY08_02140	COG0549	Belongs to the carbamate kinase family
PFY08_02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PFY08_02155	COG0277	FAD linked oxidase domain protein
PFY08_02160	COG0366	Alpha amylase catalytic
PFY08_02165	COG2190	(PTS) system
PFY08_02165	COG1263	PTS System
PFY08_02165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_02195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PFY08_02215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PFY08_02220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PFY08_02225	COG1116	anion transmembrane transporter activity
PFY08_02275	COG2270	Major facilitator Superfamily
PFY08_02305	COG2310	stress, protein
PFY08_02310	COG2310	stress, protein
PFY08_02315	COG2310	stress, protein
PFY08_02320	COG0861	Integral membrane protein TerC family
PFY08_02330	COG3853	Toxic anion resistance protein (TelA)
PFY08_02345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PFY08_02355	COG1295	ribonuclease BN
PFY08_02360	COG2217	Heavy metal translocating P-type atpase
PFY08_02365	COG0697	spore germination
PFY08_02375	COG0681	Belongs to the peptidase S26 family
PFY08_02385	COG0586	Pfam SNARE associated Golgi protein
PFY08_02400	COG3871	stress protein (general stress protein 26)
PFY08_02405	COG0387	Pfam Sodium calcium exchanger
PFY08_02415	COG0535	radical SAM domain protein
PFY08_02435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PFY08_02440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFY08_02460	COG3829	transcription factor binding
PFY08_02470	COG0833	amino acid
PFY08_02475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PFY08_02505	COG1263	PTS System
PFY08_02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_02510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PFY08_02525	COG0463	Glycosyl transferase, family 2
PFY08_02535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PFY08_02535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PFY08_02555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PFY08_02575	COG1228	amidohydrolase
PFY08_02580	COG1090	epimerase
PFY08_02610	COG1988	membrane-bound metal-dependent
PFY08_02615	COG1194	a g-specific adenine glycosylase
PFY08_02640	COG1132	(ABC) transporter
PFY08_02645	COG4129	membrane
PFY08_02650	COG0070	glutamate synthase
PFY08_02650	COG0069	glutamate synthase activity
PFY08_02650	COG0067	glutamate synthase
PFY08_02660	COG4555	ABC transporter
PFY08_02680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PFY08_02685	COG0735	belongs to the Fur family
PFY08_02805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PFY08_02830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PFY08_02835	COG5001	Diguanylate cyclase
PFY08_02835	COG1716	ATPase activity
PFY08_02840	COG2766	serine protein kinase
PFY08_02860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PFY08_02870	COG1585	Membrane protein implicated in regulation of membrane protease activity
PFY08_02875	COG2268	Band 7 protein
PFY08_02885	COG3290	protein histidine kinase activity
PFY08_02890	COG4565	transcriptional regulatory protein
PFY08_02895	COG2851	Citrate transporter
PFY08_02920	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PFY08_02925	COG3842	ATPase activity
PFY08_02930	COG1175	transmembrane transport
PFY08_02935	COG0395	ABC-type sugar transport system, permease component
PFY08_02945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PFY08_02950	COG0745	RESPONSE REGULATOR receiver
PFY08_02955	COG5002	protein histidine kinase activity
PFY08_02965	COG4990	cell redox homeostasis
PFY08_02975	COG3290	protein histidine kinase activity
PFY08_02980	COG4565	transcriptional regulatory protein
PFY08_02985	COG3493	citrate carrier protein
PFY08_02990	COG0281	malic enzyme
PFY08_03000	COG0697	spore germination
PFY08_03005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_03015	COG5002	protein histidine kinase activity
PFY08_03035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PFY08_03040	COG3383	formate dehydrogenase (NAD+) activity
PFY08_03045	COG2427	Protein of unknown function (DUF1641)
PFY08_03060	COG0531	amino acid
PFY08_03070	COG0640	Transcriptional regulator
PFY08_03075	COG2217	Heavy metal translocating P-type atpase
PFY08_03080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFY08_03115	COG2720	vancomycin resistance protein
PFY08_03120	COG1316	TRANSCRIPTIONal
PFY08_03125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_03130	COG0346	lactoylglutathione lyase activity
PFY08_03135	COG1253	flavin adenine dinucleotide binding
PFY08_03140	COG1027	Aspartate ammonia-lyase
PFY08_03145	COG1620	l-lactate permease
PFY08_03160	COG3104	oligopeptide transport
PFY08_03165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_03170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_03175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_03195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PFY08_03205	COG4548	von Willebrand factor, type A
PFY08_03210	COG0714	Associated with various cellular activities
PFY08_03230	COG0531	amino acid
PFY08_03235	COG2188	Transcriptional regulator
PFY08_03240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_03240	COG1263	PTS System
PFY08_03245	COG0366	Alpha amylase catalytic
PFY08_03260	COG0697	spore germination
PFY08_03265	COG4585	Histidine kinase
PFY08_03270	COG2197	response regulator
PFY08_03275	COG1404	Belongs to the peptidase S8 family
PFY08_03285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PFY08_03290	COG1115	amino acid carrier protein
PFY08_03295	COG1126	abc transporter atp-binding protein
PFY08_03300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PFY08_03305	COG0765	amino acid transport
PFY08_03310	COG0765	amino acid transport
PFY08_03315	COG0833	amino acid
PFY08_03340	COG2378	regulation of single-species biofilm formation
PFY08_03345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFY08_03350	COG5002	protein histidine kinase activity
PFY08_03365	COG0659	secondary active sulfate transmembrane transporter activity
PFY08_03380	COG2271	Major facilitator Superfamily
PFY08_03385	COG1846	Transcriptional regulator
PFY08_03390	COG0477	Major facilitator Superfamily
PFY08_03395	COG1609	Transcriptional regulator
PFY08_03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFY08_03415	COG1172	Belongs to the binding-protein-dependent transport system permease family
PFY08_03420	COG1879	ABC-type sugar transport system periplasmic component
PFY08_03445	COG1063	alcohol dehydrogenase
PFY08_03495	COG0840	transmembrane signaling receptor activity
PFY08_03500	COG3583	domain protein
PFY08_03500	COG3584	3D domain protein
PFY08_03505	COG1476	TRANSCRIPTIONal
PFY08_03525	COG3104	oligopeptide transport
PFY08_03530	COG1114	Component of the transport system for branched-chain amino acids
PFY08_03545	COG1113	amino acid transport
PFY08_03550	COG2252	PERMEase
PFY08_03565	COG2153	protein acetylation
PFY08_03575	COG0475	glutathione-regulated potassium exporter activity
PFY08_03575	COG0569	domain protein
PFY08_03590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PFY08_03600	COG0833	amino acid
PFY08_03605	COG4990	cell redox homeostasis
PFY08_03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFY08_03625	COG0697	spore germination
PFY08_03630	COG0531	amino acid
PFY08_03645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PFY08_03650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PFY08_03655	COG1918	ferrous iron import across plasma membrane
PFY08_03655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PFY08_03660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PFY08_03665	COG0573	inorganic phosphate transmembrane transporter activity
PFY08_03670	COG0581	inorganic phosphate transmembrane transporter activity
PFY08_03680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PFY08_03800	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PFY08_03820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PFY08_03825	COG1116	anion transmembrane transporter activity
PFY08_03830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PFY08_03835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PFY08_03840	COG0352	thiamine-phosphate diphosphorylase activity
PFY08_03845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PFY08_03850	COG2104	thiamine diphosphate biosynthetic process
PFY08_03860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PFY08_03865	COG0351	phosphomethylpyrimidine kinase
PFY08_03905	COG2205	protein histidine kinase activity
PFY08_03910	COG2814	Major facilitator Superfamily
PFY08_03915	COG1846	Transcriptional regulator
PFY08_03940	COG1136	(ABC) transporter
PFY08_03955	COG1172	Belongs to the binding-protein-dependent transport system permease family
PFY08_03960	COG1129	ABC transporter
PFY08_03970	COG2252	PERMEase
PFY08_03975	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_03990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFY08_03995	COG1621	beta-fructofuranosidase activity
PFY08_04000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_04000	COG1263	PTS System
PFY08_04005	COG1609	Transcriptional regulator
PFY08_04055	COG0778	Nitroreductase
PFY08_04060	COG2719	SpoVR family
PFY08_04070	COG1414	Transcriptional regulator
PFY08_04085	COG0446	pyridine nucleotide-disulphide oxidoreductase
PFY08_04090	COG1937	Protein conserved in bacteria
PFY08_04095	COG0425	Belongs to the sulfur carrier protein TusA family
PFY08_04095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_04100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_04100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_04105	COG0425	Belongs to the sulfur carrier protein TusA family
PFY08_04110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_04110	COG0425	Belongs to the sulfur carrier protein TusA family
PFY08_04115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_04120	COG2210	Belongs to the sulfur carrier protein TusA family
PFY08_04125	COG0730	response to heat
PFY08_04135	COG1316	TRANSCRIPTIONal
PFY08_04140	COG0604	alcohol dehydrogenase
PFY08_04145	COG1283	sodium-dependent phosphate transmembrane transporter activity
PFY08_04160	COG3711	transcriptional antiterminator
PFY08_04160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PFY08_04165	COG1447	Phosphotransferase system cellobiose-specific component IIA
PFY08_04170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PFY08_04190	COG1388	LysM domain
PFY08_04190	COG3584	3D domain protein
PFY08_04195	COG0577	efflux transmembrane transporter activity
PFY08_04200	COG1136	(ABC) transporter
PFY08_04210	COG5522	Integral membrane protein (intg_mem_TP0381)
PFY08_04225	COG1114	Component of the transport system for branched-chain amino acids
PFY08_04230	COG3546	catalase activity
PFY08_04265	COG0586	Pfam SNARE associated Golgi protein
PFY08_04300	COG0531	amino acid
PFY08_04305	COG0475	glutathione-regulated potassium exporter activity
PFY08_04315	COG1737	Transcriptional regulator
PFY08_04325	COG1263	PTS System
PFY08_04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_04335	COG2259	Doxx family
PFY08_04355	COG1522	sequence-specific DNA binding
PFY08_04360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PFY08_04360	COG0165	Argininosuccinate lyase
PFY08_04365	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_04385	COG1309	transcriptional regulator
PFY08_04390	COG2814	Major facilitator Superfamily
PFY08_04395	COG1733	regulation of RNA biosynthetic process
PFY08_04435	COG0693	protein deglycase activity
PFY08_04440	COG0693	protein deglycase activity
PFY08_04440	COG0753	catalase activity
PFY08_04450	COG0531	amino acid
PFY08_04465	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_04470	COG1132	(ABC) transporter
PFY08_04475	COG1132	(ABC) transporter
PFY08_04480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PFY08_04485	COG0765	amino acid transport
PFY08_04490	COG1126	abc transporter atp-binding protein
PFY08_04505	COG0189	ligase activity
PFY08_04535	COG0028	Belongs to the TPP enzyme family
PFY08_04540	COG3527	Alpha-acetolactate decarboxylase
PFY08_04550	COG0561	phosphatase activity
PFY08_04560	COG5632	N-Acetylmuramoyl-L-alanine amidase
PFY08_04560	COG3409	Peptidoglycan-binding domain 1 protein
PFY08_04565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PFY08_04570	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_04585	COG0659	secondary active sulfate transmembrane transporter activity
PFY08_04590	COG2244	polysaccharide biosynthetic process
PFY08_04610	COG1024	Enoyl-CoA hydratase
PFY08_04630	COG1363	Peptidase, m42
PFY08_04665	COG0601	transmembrane transport
PFY08_04670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFY08_04675	COG0444	Belongs to the ABC transporter superfamily
PFY08_04680	COG4608	Belongs to the ABC transporter superfamily
PFY08_04690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_04830	COG0477	Major facilitator Superfamily
PFY08_04835	COG3290	protein histidine kinase activity
PFY08_04840	COG4565	transcriptional regulatory protein
PFY08_04845	COG3181	Tripartite tricarboxylate transporter family receptor
PFY08_04870	COG1401	restriction endodeoxyribonuclease activity
PFY08_04920	COG0789	Transcriptional regulator
PFY08_04920	COG4978	Transcriptional regulator
PFY08_04935	COG0305	Participates in initiation and elongation during chromosome replication
PFY08_04965	COG0477	Major facilitator Superfamily
PFY08_04990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_05015	COG1073	alpha beta
PFY08_05055	COG1183	phosphatidylcholine synthase activity
PFY08_05070	COG2376	Dihydroxyacetone kinase
PFY08_05080	COG2376	Dihydroxyacetone kinase
PFY08_05110	COG2373	Large extracellular alpha-helical protein
PFY08_05175	COG1191	sigma factor activity
PFY08_05185	COG2208	phosphoserine phosphatase activity
PFY08_05190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PFY08_05195	COG0784	Response regulator, receiver
PFY08_05195	COG5002	protein histidine kinase activity
PFY08_05195	COG2205	protein histidine kinase activity
PFY08_05235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
PFY08_05255	COG0420	3'-5' exonuclease activity
PFY08_05260	COG4717	serine-type aminopeptidase activity
PFY08_05275	COG1280	lysine exporter protein (LysE YggA)
PFY08_05280	COG0346	lactoylglutathione lyase activity
PFY08_05285	COG0346	lactoylglutathione lyase activity
PFY08_05290	COG0457	Tetratricopeptide repeat
PFY08_05300	COG2267	carboxylic ester hydrolase activity
PFY08_05325	COG2140	Oxalate decarboxylase
PFY08_05330	COG3620	sequence-specific DNA binding
PFY08_05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PFY08_05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PFY08_05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PFY08_05355	COG1695	Transcriptional regulator
PFY08_05370	COG3973	AAA domain
PFY08_05400	COG4980	gas vesicle protein
PFY08_05405	COG0537	adenosine 5'-monophosphoramidase activity
PFY08_05410	COG1131	(ABC) transporter
PFY08_05415	COG4473	ABC transporter
PFY08_05440	COG3402	PFAM membrane-flanked domain
PFY08_05445	COG3428	Bacterial PH domain
PFY08_05480	COG0697	spore germination
PFY08_05485	COG3402	PFAM membrane-flanked domain
PFY08_05495	COG2329	Antibiotic biosynthesis monooxygenase
PFY08_05500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PFY08_05515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PFY08_05550	COG1309	transcriptional regulator
PFY08_05555	COG1511	domain protein
PFY08_05570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_05585	COG1234	tRNA 3'-trailer cleavage
PFY08_05590	COG0095	Lipoate-protein ligase
PFY08_05600	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_05610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PFY08_05620	COG4208	sulfate ABC transporter
PFY08_05640	COG1408	metallophosphoesterase
PFY08_05645	COG1078	dGTPase activity
PFY08_05655	COG1595	DNA-templated transcription, initiation
PFY08_05660	COG3708	Transcriptional regulator
PFY08_05660	COG2207	Transcriptional regulator
PFY08_05670	COG2205	protein histidine kinase activity
PFY08_05675	COG0745	RESPONSE REGULATOR receiver
PFY08_05695	COG0501	Belongs to the peptidase M48B family
PFY08_05700	COG0840	transmembrane signaling receptor activity
PFY08_05705	COG3693	PFAM glycoside hydrolase, family 10
PFY08_05715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PFY08_05720	COG2224	Isocitrate lyase
PFY08_05760	COG0398	Pfam SNARE associated Golgi protein
PFY08_05820	COG0179	Fumarylacetoacetate (FAA) hydrolase
PFY08_05845	COG0367	asparagine synthase
PFY08_05855	COG0753	catalase activity
PFY08_05860	COG0004	ammonium transporteR
PFY08_05880	COG2996	Protein conserved in bacteria
PFY08_05895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_05910	COG0561	phosphatase activity
PFY08_05930	COG2267	carboxylic ester hydrolase activity
PFY08_05950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PFY08_05955	COG5504	Zn-dependent protease
PFY08_05965	COG0180	Tryptophanyl-tRNA synthetase
PFY08_05975	COG4166	transmembrane transport
PFY08_05980	COG0601	transmembrane transport
PFY08_05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFY08_05990	COG0444	Belongs to the ABC transporter superfamily
PFY08_05995	COG4608	Belongs to the ABC transporter superfamily
PFY08_06000	COG0534	Mate efflux family protein
PFY08_06005	COG4166	transmembrane transport
PFY08_06020	COG0861	Integral membrane protein TerC family
PFY08_06040	COG1164	Oligoendopeptidase f
PFY08_06055	COG2346	COG2346, Truncated hemoglobins
PFY08_06060	COG4116	CYTH
PFY08_06070	COG2357	RelA SpoT domain protein
PFY08_06080	COG0564	pseudouridine synthase activity
PFY08_06095	COG0772	Belongs to the SEDS family
PFY08_06100	COG1216	Glycosyl transferase, family 2
PFY08_06120	COG0457	Tetratricopeptide repeat
PFY08_06120	COG0463	Glycosyl transferase, family 2
PFY08_06140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PFY08_06155	COG1091	dTDP-4-dehydrorhamnose reductase activity
PFY08_06200	COG2153	protein acetylation
PFY08_06210	COG2382	esterase
PFY08_06230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFY08_06240	COG0512	Glutamine amidotransferase of anthranilate synthase
PFY08_06240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PFY08_06275	COG1620	l-lactate permease
PFY08_06280	COG5634	Uncharacterized conserved protein (DUF2278)
PFY08_06330	COG0508	dehydrogenase complex catalyzes the overall conversion of
PFY08_06340	COG1476	TRANSCRIPTIONal
PFY08_06455	COG4974	Belongs to the 'phage' integrase family
PFY08_06485	COG1686	Belongs to the peptidase S11 family
PFY08_06490	COG0681	Belongs to the peptidase S26 family
PFY08_06535	COG1176	ABC-type spermidine putrescine transport system, permease component I
PFY08_06540	COG1177	transmembrane transport
PFY08_06555	COG2409	Drug exporters of the RND superfamily
PFY08_06565	COG0564	pseudouridine synthase activity
PFY08_06575	COG2340	Cysteine-rich secretory protein family
PFY08_06580	COG0247	lactate metabolic process
PFY08_06585	COG0277	FAD linked oxidase domain protein
PFY08_06590	COG3835	regulator
PFY08_06600	COG0745	RESPONSE REGULATOR receiver
PFY08_06605	COG5002	protein histidine kinase activity
PFY08_06610	COG2186	Transcriptional regulator
PFY08_06630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PFY08_06640	COG2116	formate transmembrane transporter activity
PFY08_06645	COG0861	Integral membrane protein TerC family
PFY08_06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PFY08_06660	COG2030	dehydratase
PFY08_06680	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_06685	COG3243	poly(R)-hydroxyalkanoic acid synthase
PFY08_06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PFY08_06710	COG1840	ABC-type Fe3 transport system, periplasmic component
PFY08_06740	COG1349	DNA-binding transcription factor activity
PFY08_06750	COG0235	Class ii aldolase
PFY08_06760	COG2861	carbohydrate metabolic process
PFY08_06770	COG3852	Histidine kinase
PFY08_06775	COG1846	Transcriptional regulator
PFY08_06785	COG2318	DinB family
PFY08_06795	COG5002	protein histidine kinase activity
PFY08_06805	COG0720	synthase
PFY08_06820	COG4873	Protein conserved in bacteria
PFY08_06850	COG1780	Probably involved in ribonucleotide reductase function
PFY08_06855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFY08_06875	COG1725	Transcriptional regulator
PFY08_06880	COG1131	(ABC) transporter
PFY08_06890	COG1131	(ABC) transporter
PFY08_06910	COG1522	sequence-specific DNA binding
PFY08_06920	COG1335	isochorismatase
PFY08_06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
PFY08_06935	COG2070	2-Nitropropane dioxygenase
PFY08_06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFY08_06950	COG1696	Membrane protein involved in D-alanine export
PFY08_06975	COG0716	FMN binding
PFY08_06990	COG3173	Aminoglycoside phosphotransferase
PFY08_07030	COG1846	Transcriptional regulator
PFY08_07040	COG1301	dicarboxylic acid transport
PFY08_07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PFY08_07050	COG4709	membrane
PFY08_07055	COG3874	Sporulation protein YtfJ
PFY08_07075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PFY08_07080	COG0028	Belongs to the TPP enzyme family
PFY08_07085	COG0440	acetolactate synthase activity
PFY08_07160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PFY08_07175	COG1183	phosphatidylcholine synthase activity
PFY08_07180	COG1368	sulfuric ester hydrolase activity
PFY08_07190	COG0019	diaminopimelate decarboxylase activity
PFY08_07210	COG0529	Catalyzes the synthesis of activated sulfate
PFY08_07215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PFY08_07235	COG1648	precorrin-2 dehydrogenase activity
PFY08_07240	COG0733	neurotransmitter:sodium symporter activity
PFY08_07260	COG1757	Na H antiporter
PFY08_07275	COG4758	membrane
PFY08_07280	COG4585	Histidine kinase
PFY08_07285	COG2197	response regulator
PFY08_07295	COG1114	Component of the transport system for branched-chain amino acids
PFY08_07345	COG0730	response to heat
PFY08_07350	COG0306	phosphate transporter
PFY08_07355	COG1392	Phosphate transport regulator
PFY08_07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PFY08_07375	COG3852	Histidine kinase
PFY08_07380	COG1801	Protein of unknown function DUF72
PFY08_07390	COG0582	viral genome integration into host DNA
PFY08_07395	COG5002	protein histidine kinase activity
PFY08_07410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFY08_07410	COG0392	lysyltransferase activity
PFY08_07425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PFY08_07430	COG1686	Belongs to the peptidase S11 family
PFY08_07435	COG2715	membrane protein required for spore maturation
PFY08_07440	COG0700	Nucleoside recognition
PFY08_07445	COG1187	pseudouridine synthase activity
PFY08_07455	COG1333	cytochrome c biogenesis protein
PFY08_07460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PFY08_07465	COG0745	RESPONSE REGULATOR receiver
PFY08_07470	COG5002	protein histidine kinase activity
PFY08_07475	COG2096	Adenosyltransferase
PFY08_07490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PFY08_07495	COG1141	Ferredoxin
PFY08_07505	COG0514	ATP-dependent DNA helicase (RecQ)
PFY08_07510	COG1266	CAAX protease self-immunity
PFY08_07520	COG1408	metallophosphoesterase
PFY08_07525	COG0789	Transcriptional regulator
PFY08_07535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PFY08_07555	COG0492	ferredoxin-NADP+ reductase activity
PFY08_07560	COG0252	asparaginase activity
PFY08_07630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PFY08_07645	COG0142	geranyltranstransferase activity
PFY08_07655	COG0142	geranyltranstransferase activity
PFY08_07680	COG0457	Tetratricopeptide repeat
PFY08_07700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PFY08_07705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PFY08_07705	COG2010	Cytochrome c
PFY08_07710	COG4347	Protein of unknown function (DUF1405)
PFY08_07725	COG2738	Putative neutral zinc metallopeptidase
PFY08_07735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_07740	COG1694	Mazg nucleotide pyrophosphohydrolase
PFY08_07760	COG0438	transferase activity, transferring glycosyl groups
PFY08_07795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PFY08_07795	COG1199	ATP-dependent helicase activity
PFY08_07815	COG3935	DnaD domain protein
PFY08_07820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PFY08_07830	COG4499	WXG100 protein secretion system (Wss), protein YukC
PFY08_07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PFY08_07885	COG0116	Belongs to the methyltransferase superfamily
PFY08_07895	COG1199	ATP-dependent helicase activity
PFY08_07900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PFY08_07910	COG0024	Methionine aminopeptidase
PFY08_07920	COG2233	PERMEase
PFY08_07925	COG2311	Membrane
PFY08_07930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PFY08_07940	COG0456	acetyltransferase
PFY08_07990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFY08_08005	COG3944	biosynthesis protein
PFY08_08015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PFY08_08030	COG1215	transferase activity, transferring glycosyl groups
PFY08_08035	COG0438	transferase activity, transferring glycosyl groups
PFY08_08050	COG0454	-acetyltransferase
PFY08_08070	COG0328	RNA-DNA hybrid ribonuclease activity
PFY08_08105	COG3403	YqcI/YcgG family
PFY08_08110	COG1280	lysine exporter protein (LysE YggA)
PFY08_08130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFY08_08135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PFY08_08145	COG0475	glutathione-regulated potassium exporter activity
PFY08_08150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFY08_08155	COG4978	Transcriptional regulator
PFY08_08155	COG0789	Transcriptional regulator
PFY08_08165	COG2323	membrane
PFY08_08170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PFY08_08205	COG1923	regulation of RNA biosynthetic process
PFY08_08215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PFY08_08220	COG1360	Flagellar Motor Protein
PFY08_08225	COG2201	protein-glutamate methylesterase activity
PFY08_08230	COG2198	Histidine kinase
PFY08_08230	COG0643	Histidine kinase
PFY08_08235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PFY08_08235	COG1776	CheC inhibitor of MCP methylation
PFY08_08250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PFY08_08270	COG1256	bacterial-type flagellum assembly
PFY08_08275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFY08_08295	COG1815	bacterial-type flagellum-dependent cell motility
PFY08_08300	COG1558	bacterial-type flagellum-dependent cell motility
PFY08_08310	COG1766	The M ring may be actively involved in energy transduction
PFY08_08315	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PFY08_08325	COG1157	protein secretion by the type III secretion system
PFY08_08360	COG0784	Response regulator, receiver
PFY08_08360	COG0835	chemotaxis
PFY08_08370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFY08_08375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFY08_08380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFY08_08385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PFY08_08390	COG0741	lytic transglycosylase activity
PFY08_08400	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PFY08_08405	COG1776	CheC inhibitor of MCP methylation
PFY08_08405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PFY08_08415	COG1338	Plays a role in the flagellum-specific transport system
PFY08_08420	COG1987	bacterial-type flagellum assembly
PFY08_08430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PFY08_08435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PFY08_08440	COG1419	protein localization to endoplasmic reticulum
PFY08_08445	COG4786	Flagellar basal body rod
PFY08_08450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFY08_08485	COG2329	Antibiotic biosynthesis monooxygenase
PFY08_08510	COG0583	DNA-binding transcription factor activity
PFY08_08560	COG0406	alpha-ribazole phosphatase activity
PFY08_08590	COG0367	asparagine synthase
PFY08_08620	COG1802	Transcriptional regulator
PFY08_08625	COG0697	spore germination
PFY08_08635	COG0523	cobalamin synthesis protein
PFY08_08640	COG0701	Predicted permease
PFY08_08655	COG1757	Na H antiporter
PFY08_08660	COG0789	Transcriptional regulator
PFY08_08685	COG0534	Mate efflux family protein
PFY08_08690	COG3340	Belongs to the peptidase S51 family
PFY08_08710	COG0785	Cytochrome C biogenesis protein
PFY08_08715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PFY08_08735	COG2733	membrane
PFY08_08770	COG1131	(ABC) transporter
PFY08_08785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFY08_08790	COG0528	UMP kinase activity
PFY08_08800	COG1027	Aspartate ammonia-lyase
PFY08_08805	COG0281	malic enzyme
PFY08_08810	COG4191	Histidine kinase
PFY08_08815	COG0784	Response regulator, receiver
PFY08_08820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PFY08_08865	COG2814	Major facilitator Superfamily
PFY08_08885	COG1695	Transcriptional regulator
PFY08_08900	COG0477	Major facilitator Superfamily
PFY08_08910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFY08_08915	COG2223	nitrite transmembrane transporter activity
PFY08_08920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PFY08_08940	COG0733	neurotransmitter:sodium symporter activity
PFY08_08950	COG5566	PFAM Mor transcription activator
PFY08_08955	COG2323	membrane
PFY08_08975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFY08_08985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PFY08_08990	COG0028	Belongs to the TPP enzyme family
PFY08_09010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PFY08_09035	COG2814	Major facilitator Superfamily
PFY08_09040	COG3384	dioxygenase
PFY08_09050	COG3279	Response regulator of the LytR AlgR family
PFY08_09055	COG0427	acetyl-CoA hydrolase
PFY08_09075	COG4166	transmembrane transport
PFY08_09080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_09100	COG1914	H( )-stimulated, divalent metal cation uptake system
PFY08_09115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFY08_09125	COG0531	amino acid
PFY08_09150	COG2309	aminopeptidase activity
PFY08_09165	COG0456	acetyltransferase
PFY08_09180	COG1309	transcriptional regulator
PFY08_09185	COG2390	Transcriptional regulator
PFY08_09195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_09200	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PFY08_09210	COG4846	Membrane protein involved in cytochrome C biogenesis
PFY08_09220	COG0006	proline dipeptidase activity
PFY08_09230	COG2132	Multicopper oxidase
PFY08_09240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFY08_09265	COG1114	Component of the transport system for branched-chain amino acids
PFY08_09275	COG2372	response to copper ion
PFY08_09275	COG1276	copper resistance
PFY08_09280	COG4549	nuclear export factor GLE1
PFY08_09285	COG0697	spore germination
PFY08_09290	COG0583	DNA-binding transcription factor activity
PFY08_09295	COG1959	2 iron, 2 sulfur cluster binding
PFY08_09300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PFY08_09305	COG0778	Nitroreductase
PFY08_09320	COG0628	permease
PFY08_09330	COG1231	oxidoreductase activity
PFY08_09335	COG0523	cobalamin synthesis protein
PFY08_09345	COG0411	ABC transporter
PFY08_09365	COG0583	DNA-binding transcription factor activity
PFY08_09375	COG1942	4-Oxalocrotonate Tautomerase
PFY08_09395	COG1271	oxidase subunit
PFY08_09400	COG1294	oxidase, subunit
PFY08_09405	COG4988	ABC transporter
PFY08_09410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PFY08_09420	COG1216	Glycosyl transferase, family 2
PFY08_09460	COG1686	Belongs to the peptidase S11 family
PFY08_09475	COG0791	NLP P60 protein
PFY08_09475	COG1388	LysM domain
PFY08_09485	COG1132	(ABC) transporter
PFY08_09490	COG0745	RESPONSE REGULATOR receiver
PFY08_09495	COG5002	protein histidine kinase activity
PFY08_09505	COG0300	oxidoreductase activity
PFY08_09535	COG0460	homoserine dehydrogenase
PFY08_09560	COG1316	TRANSCRIPTIONal
PFY08_09570	COG0745	RESPONSE REGULATOR receiver
PFY08_09575	COG5002	protein histidine kinase activity
PFY08_09590	COG1285	pathogenesis
PFY08_09600	COG1247	-acetyltransferase
PFY08_09620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFY08_09630	COG1082	Xylose isomerase domain protein TIM barrel
PFY08_09640	COG2814	Major facilitator Superfamily
PFY08_09645	COG1279	arginine transmembrane transporter activity
PFY08_09650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_09660	COG1752	Esterase of the alpha-beta hydrolase superfamily
PFY08_09695	COG0577	efflux transmembrane transporter activity
PFY08_09700	COG2002	toxin-antitoxin pair type II binding
PFY08_09705	COG1404	Belongs to the peptidase S8 family
PFY08_09715	COG3152	Membrane
PFY08_09740	COG0840	transmembrane signaling receptor activity
PFY08_09755	COG3949	Membrane
PFY08_09760	COG0783	Belongs to the Dps family
PFY08_09775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFY08_09785	COG1231	oxidoreductase activity
PFY08_09790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_09795	COG4989	oxidoreductase activity
PFY08_09800	COG0523	cobalamin synthesis protein
PFY08_09805	COG0456	acetyltransferase
PFY08_09810	COG0803	Belongs to the bacterial solute-binding protein 9 family
PFY08_09820	COG0702	epimerase
PFY08_09830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PFY08_09840	COG4166	transmembrane transport
PFY08_09865	COG5337	Spore coat protein CotH
PFY08_09870	COG1051	belongs to the nudix hydrolase family
PFY08_09875	COG0586	Pfam SNARE associated Golgi protein
PFY08_09880	COG2244	polysaccharide biosynthetic process
PFY08_09890	COG0701	Predicted permease
PFY08_09895	COG3689	TIGRFAM TIGR03943 family protein
PFY08_09900	COG1607	acyl-coa hydrolase
PFY08_09910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFY08_09925	COG0702	epimerase
PFY08_09930	COG2839	Protein conserved in bacteria
PFY08_09935	COG1253	flavin adenine dinucleotide binding
PFY08_09950	COG1114	Component of the transport system for branched-chain amino acids
PFY08_09955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFY08_09975	COG0860	N-Acetylmuramoyl-L-alanine amidase
PFY08_09985	COG1876	peptidase activity
PFY08_09995	COG0154	amidase activity
PFY08_10000	COG2211	Major facilitator Superfamily
PFY08_10015	COG0860	N-Acetylmuramoyl-L-alanine amidase
PFY08_10025	COG0561	phosphatase activity
PFY08_10040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFY08_10060	COG1819	glycosyl
PFY08_10065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_10100	COG0456	acetyltransferase
PFY08_10135	COG4499	WXG100 protein secretion system (Wss), protein YukC
PFY08_10245	COG3874	Sporulation protein YtfJ
PFY08_10270	COG2226	methyltransferase
PFY08_10290	COG1082	Xylose isomerase domain protein TIM barrel
PFY08_10295	COG0346	lactoylglutathione lyase activity
PFY08_10305	COG0604	alcohol dehydrogenase
PFY08_10310	COG1595	DNA-templated transcription, initiation
PFY08_10320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PFY08_10330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PFY08_10330	COG0426	domain, Protein
PFY08_10340	COG0386	Belongs to the glutathione peroxidase family
PFY08_10345	COG1305	Transglutaminase-like
PFY08_10350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
PFY08_10355	COG0714	Associated with various cellular activities
PFY08_10365	COG1140	nitrate reductase beta subunit
PFY08_10370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PFY08_10375	COG2181	nitrate reductase activity
PFY08_10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PFY08_10385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PFY08_10390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PFY08_10395	COG0303	'Molybdopterin
PFY08_10400	COG0314	molybdopterin synthase activity
PFY08_10410	COG2223	nitrite transmembrane transporter activity
PFY08_10430	COG1648	precorrin-2 dehydrogenase activity
PFY08_10440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PFY08_10440	COG1587	Uroporphyrinogen-III synthase
PFY08_10445	COG2146	nitrite reductase [NAD(P)H] activity
PFY08_10450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PFY08_10455	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PFY08_10490	COG2359	stage V sporulation protein S
PFY08_10515	COG0457	Tetratricopeptide repeat
PFY08_10530	COG1418	mRNA catabolic process
PFY08_10535	COG0488	(ABC) transporter
PFY08_10550	COG0629	single-stranded DNA binding
PFY08_10555	COG1413	lyase activity
PFY08_10570	COG2521	methyltransferase
PFY08_10570	COG2136	Putative SAM-dependent methyltransferase
PFY08_10575	COG0018	arginyl-trna synthetase
PFY08_10625	COG0017	Asparaginyl-tRNA synthetase
PFY08_10630	COG0733	neurotransmitter:sodium symporter activity
PFY08_10655	COG2610	gluconate transmembrane transporter activity
PFY08_10665	COG1794	racemase activity, acting on amino acids and derivatives
PFY08_10675	COG0456	acetyltransferase
PFY08_10685	COG3655	Transcriptional regulator
PFY08_10690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PFY08_10700	COG1131	(ABC) transporter
PFY08_10705	COG4473	ABC transporter
PFY08_10715	COG0546	phosphoglycolate phosphatase activity
PFY08_10730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PFY08_10745	COG0768	penicillin binding
PFY08_10755	COG0204	Acyl-transferase
PFY08_10760	COG1272	protein, Hemolysin III
PFY08_10770	COG0805	protein transport
PFY08_10780	COG1307	EDD domain protein, DegV family
PFY08_10790	COG1999	signal sequence binding
PFY08_10800	COG0367	asparagine synthase
PFY08_10815	COG0860	N-Acetylmuramoyl-L-alanine amidase
PFY08_10820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_10825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PFY08_10840	COG1335	isochorismatase
PFY08_10855	COG0668	transmembrane transport
PFY08_10860	COG2203	Gaf domain
PFY08_10860	COG4585	Histidine kinase
PFY08_10865	COG2197	response regulator
PFY08_10870	COG1737	Transcriptional regulator
PFY08_10875	COG0384	phenazine biosynthesis protein PhzF
PFY08_10880	COG1064	alcohol dehydrogenase
PFY08_10905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PFY08_10940	COG0517	IMP dehydrogenase activity
PFY08_10940	COG1125	glycine betaine transport
PFY08_10945	COG1174	glycine betaine transport
PFY08_10980	COG1253	flavin adenine dinucleotide binding
PFY08_10985	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_10990	COG5506	Protein of unknown function (DUF1694)
PFY08_11005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PFY08_11010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PFY08_11015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PFY08_11020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PFY08_11025	COG0456	acetyltransferase
PFY08_11030	COG3829	transcription factor binding
PFY08_11035	COG1509	lysine 2,3-aminomutase activity
PFY08_11070	COG0515	serine threonine protein kinase
PFY08_11070	COG3064	Membrane
PFY08_11070	COG4991	sh3 domain protein
PFY08_11080	COG0671	phosphoesterase, PA-phosphatase related
PFY08_11085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFY08_11090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PFY08_11175	COG0300	oxidoreductase activity
PFY08_11195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PFY08_11195	COG4499	WXG100 protein secretion system (Wss), protein YukC
PFY08_11205	COG2814	Major facilitator Superfamily
PFY08_11210	COG4841	protein insertion into membrane
PFY08_11215	COG0372	Belongs to the citrate synthase family
PFY08_11220	COG2079	MmgE PrpD family protein
PFY08_11225	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PFY08_11230	COG1960	acyl-CoA dehydrogenase activity
PFY08_11235	COG2084	Dehydrogenase
PFY08_11245	COG1280	lysine exporter protein (LysE YggA)
PFY08_11250	COG1024	Enoyl-CoA hydratase
PFY08_11265	COG0420	3'-5' exonuclease activity
PFY08_11270	COG0419	ATPase involved in DNA repair
PFY08_11295	COG2223	nitrite transmembrane transporter activity
PFY08_11300	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_11305	COG1169	isochorismate synthase
PFY08_11310	COG1021	2,3-dihydroxybenzoate-AMP ligase
PFY08_11315	COG3433	isochorismatase activity
PFY08_11315	COG1535	isochorismatase
PFY08_11320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PFY08_11325	COG3251	PFAM MbtH domain protein
PFY08_11330	COG2814	Major facilitator Superfamily
PFY08_11345	COG0776	regulation of translation
PFY08_11355	COG2318	DinB family
PFY08_11365	COG1115	amino acid carrier protein
PFY08_11385	COG1187	pseudouridine synthase activity
PFY08_11390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFY08_11395	COG1136	(ABC) transporter
PFY08_11420	COG0028	Belongs to the TPP enzyme family
PFY08_11455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PFY08_11480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_11525	COG1247	-acetyltransferase
PFY08_11550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PFY08_11560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_11590	COG0583	DNA-binding transcription factor activity
PFY08_11595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFY08_11615	COG0583	DNA-binding transcription factor activity
PFY08_11620	COG2258	MOSC domain
PFY08_11635	COG1132	(ABC) transporter
PFY08_11640	COG1132	(ABC) transporter
PFY08_11670	COG1396	sequence-specific DNA binding
PFY08_11700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PFY08_11705	COG1595	DNA-templated transcription, initiation
PFY08_11730	COG1649	PFAM Uncharacterised BCR, COG1649
PFY08_11755	COG2971	BadF BadG BcrA BcrD
PFY08_11765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PFY08_11775	COG1846	Transcriptional regulator
PFY08_11795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_11820	COG1309	transcriptional regulator
PFY08_11940	COG3615	Tellurite resistance protein tehB
PFY08_11940	COG0500	methyltransferase
PFY08_11955	COG3961	Belongs to the TPP enzyme family
PFY08_11960	COG1846	Transcriptional regulator
PFY08_11990	COG2195	Cleaves the N-terminal amino acid of tripeptides
PFY08_12020	COG2002	toxin-antitoxin pair type II binding
PFY08_12030	COG0730	response to heat
PFY08_12035	COG0110	maltose O-acetyltransferase activity
PFY08_12040	COG1686	Belongs to the peptidase S11 family
PFY08_12055	COG2814	Major facilitator Superfamily
PFY08_12090	COG2312	Erythromycin esterase
PFY08_12100	COG0741	lytic transglycosylase activity
PFY08_12105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_12145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PFY08_12150	COG0768	penicillin binding
PFY08_12155	COG1595	DNA-templated transcription, initiation
PFY08_12165	COG0768	penicillin binding
PFY08_12170	COG0768	penicillin binding
PFY08_12180	COG1408	metallophosphoesterase
PFY08_12190	COG1131	(ABC) transporter
PFY08_12200	COG1309	transcriptional regulator
PFY08_12215	COG1960	acyl-CoA dehydrogenase activity
PFY08_12220	COG0439	Biotin carboxylase
PFY08_12225	COG0511	ligase activity, forming carbon-carbon bonds
PFY08_12230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PFY08_12235	COG1024	Enoyl-CoA hydratase
PFY08_12240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PFY08_12245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PFY08_12270	COG0572	uridine kinase
PFY08_12295	COG1686	Belongs to the peptidase S11 family
PFY08_12320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PFY08_12335	COG3227	Zinc metalloprotease (Elastase)
PFY08_12340	COG2207	Transcriptional regulator
PFY08_12370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PFY08_12385	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_12390	COG1733	regulation of RNA biosynthetic process
PFY08_12395	COG2226	methyltransferase
PFY08_12435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_12445	COG2368	4-hydroxyphenylacetate
PFY08_12460	COG1063	alcohol dehydrogenase
PFY08_12470	COG2323	membrane
PFY08_12475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PFY08_12485	COG3386	PFAM SMP-30 Gluconolaconase
PFY08_12495	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PFY08_12500	COG3773	Cell wall hydrolase
PFY08_12505	COG0596	Alpha beta hydrolase
PFY08_12515	COG0745	RESPONSE REGULATOR receiver
PFY08_12520	COG2205	protein histidine kinase activity
PFY08_12530	COG0488	(ABC) transporter
PFY08_12540	COG1136	(ABC) transporter
PFY08_12545	COG0577	efflux transmembrane transporter activity
PFY08_12565	COG0460	homoserine dehydrogenase
PFY08_12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_12580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PFY08_12610	COG0582	viral genome integration into host DNA
PFY08_12635	COG1396	sequence-specific DNA binding
PFY08_12660	COG2002	toxin-antitoxin pair type II binding
PFY08_12715	COG0582	viral genome integration into host DNA
PFY08_12835	COG5632	N-Acetylmuramoyl-L-alanine amidase
PFY08_12835	COG1388	LysM domain
PFY08_12835	COG3409	Peptidoglycan-binding domain 1 protein
PFY08_12880	COG2124	cytochrome p450
PFY08_12915	COG0561	phosphatase activity
PFY08_12920	COG5002	protein histidine kinase activity
PFY08_12925	COG0768	penicillin binding
PFY08_12935	COG1819	glycosyl
PFY08_12940	COG1794	racemase activity, acting on amino acids and derivatives
PFY08_12965	COG2205	protein histidine kinase activity
PFY08_13030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFY08_13035	COG0604	alcohol dehydrogenase
PFY08_13040	COG0671	phosphoesterase, PA-phosphatase related
PFY08_13045	COG0768	penicillin binding
PFY08_13105	COG0789	Transcriptional regulator
PFY08_13110	COG2814	Major facilitator Superfamily
PFY08_13115	COG4978	Transcriptional regulator
PFY08_13115	COG0789	Transcriptional regulator
PFY08_13135	COG0584	glycerophosphoryl diester phosphodiesterase
PFY08_13155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_13160	COG0697	spore germination
PFY08_13195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PFY08_13205	COG2223	nitrite transmembrane transporter activity
PFY08_13225	COG0592	DNA-directed DNA polymerase activity
PFY08_13245	COG0251	oxidation-reduction process
PFY08_13250	COG3878	Protein conserved in bacteria
PFY08_13275	COG4667	esterase of the alpha-beta hydrolase superfamily
PFY08_13315	COG0322	excinuclease ABC activity
PFY08_13345	COG1131	(ABC) transporter
PFY08_13365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PFY08_13395	COG1011	Hydrolase
PFY08_13400	COG0745	RESPONSE REGULATOR receiver
PFY08_13405	COG5002	protein histidine kinase activity
PFY08_13420	COG1136	(ABC) transporter
PFY08_13425	COG0577	efflux transmembrane transporter activity
PFY08_13430	COG1073	alpha beta
PFY08_13435	COG0657	acetylesterase activity
PFY08_13440	COG0076	glutamate decarboxylase activity
PFY08_13455	COG1523	belongs to the glycosyl hydrolase 13 family
PFY08_13460	COG3227	Zinc metalloprotease (Elastase)
PFY08_13465	COG0737	Belongs to the 5'-nucleotidase family
PFY08_13485	COG0201	protein transport
PFY08_13490	COG0697	spore germination
PFY08_13495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_13505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PFY08_13535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_13550	COG2959	enzyme of heme biosynthesis
PFY08_13590	COG1309	transcriptional regulator
PFY08_13610	COG3284	Transcriptional regulator
PFY08_13625	COG1349	DNA-binding transcription factor activity
PFY08_13640	COG1959	2 iron, 2 sulfur cluster binding
PFY08_13655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PFY08_13660	COG0508	dehydrogenase complex catalyzes the overall conversion of
PFY08_13665	COG0022	dehydrogenase e1 component
PFY08_13670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PFY08_13680	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_13710	COG4176	ABC-type proline glycine betaine transport system permease component
PFY08_13715	COG0517	IMP dehydrogenase activity
PFY08_13715	COG4175	Glycine betaine
PFY08_13745	COG2153	protein acetylation
PFY08_13750	COG3397	chitin binding
PFY08_13755	COG1819	glycosyl
PFY08_13775	COG2205	protein histidine kinase activity
PFY08_13780	COG2226	methyltransferase
PFY08_13785	COG2315	Protein conserved in bacteria
PFY08_13835	COG3973	AAA domain
PFY08_13850	COG0514	ATP-dependent DNA helicase (RecQ)
PFY08_13895	COG4637	Psort location Cytoplasmic, score
PFY08_13915	COG3397	chitin binding
PFY08_13930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PFY08_13935	COG1115	amino acid carrier protein
PFY08_13940	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_13945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PFY08_13955	COG3938	Belongs to the proline racemase family
PFY08_13960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PFY08_14005	COG1078	dGTPase activity
PFY08_14010	COG0586	Pfam SNARE associated Golgi protein
PFY08_14020	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFY08_14030	COG4166	transmembrane transport
PFY08_14040	COG4948	Mandelate Racemase Muconate Lactonizing
PFY08_14055	COG0667	Aldo Keto reductase
PFY08_14100	COG3850	Histidine kinase
PFY08_14100	COG5002	protein histidine kinase activity
PFY08_14105	COG0745	RESPONSE REGULATOR receiver
PFY08_14140	COG1164	Oligoendopeptidase f
PFY08_14145	COG1307	EDD domain protein, DegV family
PFY08_14185	COG2814	Major facilitator Superfamily
PFY08_14195	COG1664	Polymer-forming cytoskeletal
PFY08_14200	COG0789	Transcriptional regulator
PFY08_14205	COG4533	DNA binding
PFY08_14210	COG0477	Major facilitator Superfamily
PFY08_14210	COG2814	Major facilitator Superfamily
PFY08_14230	COG2261	transglycosylase associated protein
PFY08_14245	COG2226	methyltransferase
PFY08_14280	COG0436	Aminotransferase
PFY08_14285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PFY08_14360	COG0628	permease
PFY08_14375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFY08_14380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PFY08_14385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PFY08_14425	COG2746	aminoglycoside 3-N-acetyltransferase activity
PFY08_14435	COG0697	spore germination
PFY08_14440	COG2318	DinB family
PFY08_14460	COG4912	Dna alkylation repair
PFY08_14465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PFY08_14470	COG0346	lactoylglutathione lyase activity
PFY08_14475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_14490	COG0861	Integral membrane protein TerC family
PFY08_14495	COG1368	sulfuric ester hydrolase activity
PFY08_14500	COG0488	(ABC) transporter
PFY08_14505	COG1033	growth of symbiont in host cell
PFY08_14505	COG2409	Drug exporters of the RND superfamily
PFY08_14510	COG1309	transcriptional regulator
PFY08_14525	COG0287	Prephenate dehydrogenase
PFY08_14540	COG1605	Chorismate mutase
PFY08_14540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PFY08_14580	COG3584	3D domain protein
PFY08_14580	COG1388	LysM domain
PFY08_14590	COG0346	lactoylglutathione lyase activity
PFY08_14595	COG0277	FAD linked oxidase domain protein
PFY08_14605	COG1309	transcriptional regulator
PFY08_14620	COG1879	ABC-type sugar transport system periplasmic component
PFY08_14625	COG1172	Belongs to the binding-protein-dependent transport system permease family
PFY08_14630	COG1172	Belongs to the binding-protein-dependent transport system permease family
PFY08_14640	COG2390	Transcriptional regulator
PFY08_14645	COG1070	Carbohydrate kinase
PFY08_14670	COG2329	Antibiotic biosynthesis monooxygenase
PFY08_14690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_14705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFY08_14710	COG4187	Peptidase family M20/M25/M40
PFY08_14715	COG1414	Transcriptional regulator
PFY08_14720	COG0833	amino acid
PFY08_14730	COG3239	Fatty acid desaturase
PFY08_14740	COG2720	vancomycin resistance protein
PFY08_14745	COG1785	Belongs to the alkaline phosphatase family
PFY08_14755	COG3655	Transcriptional regulator
PFY08_14775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_14780	COG0346	lactoylglutathione lyase activity
PFY08_14805	COG0714	Associated with various cellular activities
PFY08_14830	COG0463	Glycosyl transferase, family 2
PFY08_14860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PFY08_14865	COG0753	catalase activity
PFY08_14905	COG0714	Associated with various cellular activities
PFY08_14975	COG0778	Nitroreductase
PFY08_14980	COG1846	Transcriptional regulator
PFY08_15000	COG4884	unkown
PFY08_15000	COG3831	ATPase activity
PFY08_15025	COG0037	tRNA processing
PFY08_15025	COG0590	tRNA wobble adenosine to inosine editing
PFY08_15030	COG0456	acetyltransferase
PFY08_15045	COG0697	spore germination
PFY08_15050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_15105	COG0730	response to heat
PFY08_15115	COG0833	amino acid
PFY08_15125	COG4335	DNA alkylation repair
PFY08_15135	COG5002	protein histidine kinase activity
PFY08_15140	COG0745	RESPONSE REGULATOR receiver
PFY08_15150	COG1136	(ABC) transporter
PFY08_15180	COG0768	penicillin binding
PFY08_15215	COG1984	allophanate hydrolase subunit 2
PFY08_15220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PFY08_15225	COG1414	Transcriptional regulator
PFY08_15240	COG0640	Transcriptional regulator
PFY08_15250	COG1960	acyl-CoA dehydrogenase activity
PFY08_15265	COG3314	Sporulation integral membrane protein YlbJ
PFY08_15285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PFY08_15310	COG0574	Belongs to the PEP-utilizing enzyme family
PFY08_15310	COG3848	Pyruvate phosphate dikinase
PFY08_15315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_15335	COG1063	alcohol dehydrogenase
PFY08_15345	COG0252	asparaginase activity
PFY08_15350	COG1396	sequence-specific DNA binding
PFY08_15380	COG5002	protein histidine kinase activity
PFY08_15410	COG2207	Transcriptional regulator
PFY08_15425	COG0322	excinuclease ABC activity
PFY08_15430	COG0531	amino acid
PFY08_15435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFY08_15445	COG0531	amino acid
PFY08_15450	COG0697	spore germination
PFY08_15455	COG0784	Response regulator, receiver
PFY08_15470	COG1115	amino acid carrier protein
PFY08_15480	COG2124	cytochrome p450
PFY08_15500	COG2267	carboxylic ester hydrolase activity
PFY08_15505	COG1335	isochorismatase
PFY08_15525	COG0583	DNA-binding transcription factor activity
PFY08_15530	COG1846	Transcriptional regulator
PFY08_15535	COG0598	Magnesium transport protein CorA
PFY08_15555	COG1073	alpha beta
PFY08_15575	COG0415	Belongs to the DNA photolyase family
PFY08_15590	COG0288	reversible hydration of carbon dioxide
PFY08_15600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PFY08_15605	COG5609	conserved protein (DUF2294)
PFY08_15620	COG0697	spore germination
PFY08_15630	COG0456	acetyltransferase
PFY08_15635	COG1575	Belongs to the MenA family. Type 1 subfamily
PFY08_15645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_15655	COG0798	PFAM Bile acid sodium symporter
PFY08_15660	COG0346	lactoylglutathione lyase activity
PFY08_15665	COG0640	Transcriptional regulator
PFY08_15675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFY08_15680	COG3320	Male sterility
PFY08_15680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFY08_15685	COG1309	transcriptional regulator
PFY08_15690	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_15695	COG1522	sequence-specific DNA binding
PFY08_15710	COG0346	lactoylglutathione lyase activity
PFY08_15735	COG1309	transcriptional regulator
PFY08_15800	COG0745	RESPONSE REGULATOR receiver
PFY08_15805	COG3850	Histidine kinase
PFY08_15805	COG5002	protein histidine kinase activity
PFY08_15855	COG2814	Major facilitator Superfamily
PFY08_15875	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PFY08_15885	COG1690	Belongs to the RtcB family
PFY08_15895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PFY08_15910	COG0577	efflux transmembrane transporter activity
PFY08_15930	COG3850	Histidine kinase
PFY08_15930	COG5002	protein histidine kinase activity
PFY08_15940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_15950	COG1619	proteins homologs of microcin C7 resistance protein MccF
PFY08_15995	COG0814	amino acid
PFY08_16000	COG1760	l-serine dehydratase
PFY08_16005	COG1760	l-serine dehydratase
PFY08_16015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PFY08_16020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PFY08_16030	COG1335	isochorismatase
PFY08_16035	COG1522	sequence-specific DNA binding
PFY08_16040	COG0531	amino acid
PFY08_16055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PFY08_16075	COG0662	Cupin 2, conserved barrel domain protein
PFY08_16080	COG2207	Transcriptional regulator
PFY08_16080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_16095	COG3409	Peptidoglycan-binding domain 1 protein
PFY08_16095	COG5632	N-Acetylmuramoyl-L-alanine amidase
PFY08_16135	COG5444	nuclease activity
PFY08_16185	COG1876	peptidase activity
PFY08_16190	COG2843	Capsule synthesis protein
PFY08_16200	COG0477	Major facilitator Superfamily
PFY08_16215	COG1846	Transcriptional regulator
PFY08_16220	COG2814	Major facilitator Superfamily
PFY08_16230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PFY08_16235	COG1131	(ABC) transporter
PFY08_16255	COG2031	fatty acid transporter
PFY08_16265	COG2249	NAD(P)H dehydrogenase (quinone) activity
PFY08_16320	COG1288	antiporter activity
PFY08_16325	COG2356	endonuclease I
PFY08_16340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PFY08_16360	COG1733	regulation of RNA biosynthetic process
PFY08_16365	COG0778	Nitroreductase
PFY08_16395	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_16405	COG1131	(ABC) transporter
PFY08_16430	COG1011	Hydrolase
PFY08_16440	COG2365	Tyrosine phosphatase family
PFY08_16475	COG0628	permease
PFY08_16510	COG0477	Major facilitator Superfamily
PFY08_16540	COG1253	flavin adenine dinucleotide binding
PFY08_16545	COG0789	Transcriptional regulator
PFY08_16555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PFY08_16585	COG0697	spore germination
PFY08_16595	COG1357	PFAM Pentapeptide repeats (8 copies)
PFY08_16600	COG3813	Protein conserved in bacteria
PFY08_16605	COG2706	6-phosphogluconolactonase activity
PFY08_16610	COG1070	Carbohydrate kinase
PFY08_16625	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PFY08_16630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PFY08_16635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PFY08_16645	COG0604	alcohol dehydrogenase
PFY08_16650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PFY08_16660	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_16675	COG0840	transmembrane signaling receptor activity
PFY08_16685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFY08_16685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFY08_16690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PFY08_16690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PFY08_16695	COG1733	regulation of RNA biosynthetic process
PFY08_16710	COG0656	L-ascorbic acid biosynthetic process
PFY08_16715	COG2814	Major facilitator Superfamily
PFY08_16740	COG0814	amino acid
PFY08_16775	COG1733	regulation of RNA biosynthetic process
PFY08_16780	COG2188	Transcriptional regulator
PFY08_16785	COG0673	inositol 2-dehydrogenase activity
PFY08_16790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PFY08_16795	COG1733	regulation of RNA biosynthetic process
PFY08_16800	COG1733	regulation of RNA biosynthetic process
PFY08_16825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_16845	COG0384	phenazine biosynthesis protein PhzF
PFY08_16855	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_16860	COG2249	NAD(P)H dehydrogenase (quinone) activity
PFY08_16865	COG1733	regulation of RNA biosynthetic process
PFY08_16880	COG0726	polysaccharide deacetylase
PFY08_16890	COG1191	sigma factor activity
PFY08_16900	COG1280	lysine exporter protein (LysE YggA)
PFY08_16955	COG1151	hydroxylamine reductase activity
PFY08_16980	COG2072	flavoprotein involved in K transport
PFY08_17015	COG1113	amino acid transport
PFY08_17020	COG2814	Major facilitator Superfamily
PFY08_17050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PFY08_17055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PFY08_17070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_17075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_17105	COG3739	integral membrane protein
PFY08_17135	COG0583	DNA-binding transcription factor activity
PFY08_17155	COG1193	negative regulation of DNA recombination
PFY08_17170	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PFY08_17175	COG1164	Oligoendopeptidase f
PFY08_17180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PFY08_17205	COG0584	glycerophosphoryl diester phosphodiesterase
PFY08_17215	COG0640	Transcriptional regulator
PFY08_17220	COG0604	alcohol dehydrogenase
PFY08_17230	COG0457	Tetratricopeptide repeat
PFY08_17260	COG0277	FAD linked oxidase domain protein
PFY08_17285	COG1183	phosphatidylcholine synthase activity
PFY08_17295	COG1252	NADH dehydrogenase
PFY08_17305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PFY08_17315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PFY08_17325	COG0457	Tetratricopeptide repeat
PFY08_17355	COG1309	transcriptional regulator
PFY08_17390	COG3852	Histidine kinase
PFY08_17400	COG1285	pathogenesis
PFY08_17410	COG2514	catechol 2,3-dioxygenase activity
PFY08_17415	COG2720	vancomycin resistance protein
PFY08_17450	COG0716	FMN binding
PFY08_17480	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_17490	COG0165	Argininosuccinate lyase
PFY08_17505	COG4145	pantothenate transmembrane transporter activity
PFY08_17515	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_17520	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_17530	COG1657	PFAM Prenyltransferase squalene oxidase
PFY08_17535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
PFY08_17540	COG2962	Rard protein
PFY08_17545	COG3326	Membrane
PFY08_17560	COG0489	protein tyrosine kinase activity
PFY08_17570	COG0314	molybdopterin synthase activity
PFY08_17575	COG0303	'Molybdopterin
PFY08_17580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PFY08_17585	COG2116	formate transmembrane transporter activity
PFY08_17595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PFY08_17600	COG5609	conserved protein (DUF2294)
PFY08_17605	COG2427	Protein of unknown function (DUF1641)
PFY08_17610	COG3383	formate dehydrogenase (NAD+) activity
PFY08_17615	COG0697	spore germination
PFY08_17630	COG0531	amino acid
PFY08_17665	COG2226	methyltransferase
PFY08_17670	COG4166	transmembrane transport
PFY08_17675	COG4166	transmembrane transport
PFY08_17680	COG4166	transmembrane transport
PFY08_17685	COG1316	TRANSCRIPTIONal
PFY08_17695	COG1595	DNA-templated transcription, initiation
PFY08_17705	COG1131	(ABC) transporter
PFY08_17725	COG0673	inositol 2-dehydrogenase activity
PFY08_17730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFY08_17735	COG0187	DNA topoisomerase II activity
PFY08_17740	COG1832	CoA-binding protein
PFY08_17745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFY08_17750	COG0745	RESPONSE REGULATOR receiver
PFY08_17770	COG4841	protein insertion into membrane
PFY08_17775	COG0824	Thioesterase
PFY08_17805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PFY08_17820	COG1132	(ABC) transporter
PFY08_17825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PFY08_17855	COG2211	Major facilitator Superfamily
PFY08_17865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFY08_17880	COG0183	Belongs to the thiolase family
PFY08_17885	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_17890	COG1268	BioY protein
PFY08_17895	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_17940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_17950	COG5002	protein histidine kinase activity
PFY08_17955	COG0400	carboxylic ester hydrolase activity
PFY08_17960	COG0346	lactoylglutathione lyase activity
PFY08_17965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFY08_17970	COG0069	glutamate synthase activity
PFY08_17975	COG1902	pentaerythritol trinitrate reductase activity
PFY08_17980	COG1329	Transcriptional regulator
PFY08_17985	COG0010	Belongs to the arginase family
PFY08_18035	COG4846	Membrane protein involved in cytochrome C biogenesis
PFY08_18040	COG0785	Cytochrome C biogenesis protein
PFY08_18050	COG1473	amidohydrolase
PFY08_18060	COG1131	(ABC) transporter
PFY08_18075	COG0583	DNA-binding transcription factor activity
PFY08_18085	COG1346	cytolysis
PFY08_18100	COG0730	response to heat
PFY08_18125	COG1132	(ABC) transporter
PFY08_18130	COG1132	(ABC) transporter
PFY08_18155	COG3639	organic phosphonate transmembrane transporter activity
PFY08_18165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PFY08_18170	COG0737	Belongs to the 5'-nucleotidase family
PFY08_18180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PFY08_18200	COG1695	Transcriptional regulator
PFY08_18205	COG0174	glutamine synthetase
PFY08_18210	COG0789	Transcriptional regulator
PFY08_18215	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PFY08_18220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFY08_18225	COG2860	membrane
PFY08_18235	COG0464	growth
PFY08_18270	COG1388	LysM domain
PFY08_18270	COG3584	3D domain protein
PFY08_18275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PFY08_18275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PFY08_18275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PFY08_18280	COG1105	Belongs to the carbohydrate kinase PfkB family
PFY08_18285	COG1349	DNA-binding transcription factor activity
PFY08_18290	COG1979	alcohol dehydrogenase
PFY08_18295	COG2322	membrane
PFY08_18305	COG1113	amino acid transport
PFY08_18315	COG1408	metallophosphoesterase
PFY08_18320	COG2116	formate transmembrane transporter activity
PFY08_18335	COG2217	Heavy metal translocating P-type atpase
PFY08_18340	COG2608	mercury ion transmembrane transporter activity
PFY08_18345	COG1937	Protein conserved in bacteria
PFY08_18355	COG2819	hydrolase of the alpha beta superfamily
PFY08_18360	COG1120	ATPase activity
PFY08_18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_18370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_18375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_18380	COG0708	Exodeoxyribonuclease III
PFY08_18385	COG2169	Transcriptional regulator
PFY08_18390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PFY08_18395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PFY08_18415	COG2267	carboxylic ester hydrolase activity
PFY08_18420	COG3300	MHYT domain
PFY08_18420	COG5001	Diguanylate cyclase
PFY08_18440	COG1086	Polysaccharide biosynthesis protein
PFY08_18460	COG1346	cytolysis
PFY08_18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PFY08_18480	COG2188	Transcriptional regulator
PFY08_18485	COG2723	6-phospho-beta-galactosidase activity
PFY08_18495	COG1404	Belongs to the peptidase S8 family
PFY08_18500	COG3773	Cell wall hydrolase
PFY08_18510	COG1368	sulfuric ester hydrolase activity
PFY08_18515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PFY08_18540	COG4550	Control of competence regulator ComK, YlbF/YmcA
PFY08_18550	COG1013	pyruvate-flavodoxin oxidoreductase activity
PFY08_18555	COG0674	pyruvate-flavodoxin oxidoreductase activity
PFY08_18555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PFY08_18565	COG2359	stage V sporulation protein S
PFY08_18570	COG1692	metallophosphoesterase
PFY08_18590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFY08_18595	COG1426	Protein conserved in bacteria
PFY08_18610	COG0300	oxidoreductase activity
PFY08_18615	COG0612	Peptidase, M16
PFY08_18620	COG0612	Peptidase, M16
PFY08_18625	COG1079	Belongs to the binding-protein-dependent transport system permease family
PFY08_18630	COG4603	Belongs to the binding-protein-dependent transport system permease family
PFY08_18635	COG3845	ABC transporter
PFY08_18640	COG1744	ABC transporter substrate-binding protein PnrA-like
PFY08_18645	COG2188	Transcriptional regulator
PFY08_18660	COG0740	serine-type endopeptidase activity
PFY08_18665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFY08_18675	COG0527	aspartate kinase activity
PFY08_18680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFY08_18685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFY08_18690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFY08_18695	COG1873	PFAM PRC-barrel domain
PFY08_18700	COG0612	Peptidase, M16
PFY08_18705	COG0726	polysaccharide deacetylase
PFY08_18720	COG0196	riboflavin kinase activity
PFY08_18730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PFY08_18735	COG1550	Protein conserved in bacteria
PFY08_18745	COG1358	cellular component organization or biogenesis
PFY08_18750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PFY08_18755	COG0195	Participates in both transcription termination and antitermination
PFY08_18775	COG0750	zinc metalloprotease
PFY08_18785	COG4589	Belongs to the CDS family
PFY08_18830	COG4974	Belongs to the 'phage' integrase family
PFY08_18840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFY08_18845	COG0758	DNA mediated transformation
PFY08_18850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PFY08_18890	COG1837	Belongs to the UPF0109 family
PFY08_18900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PFY08_18910	COG0552	protein localization to endoplasmic reticulum
PFY08_18915	COG1196	nuclear chromosome segregation
PFY08_18925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFY08_18930	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_18935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PFY08_18950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PFY08_18955	COG1461	Dihydroxyacetone kinase
PFY08_18960	COG1302	Protein conserved in bacteria
PFY08_18975	COG1564	THIamine pyrophosphokinase
PFY08_18980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PFY08_18990	COG2815	serine threonine protein kinase
PFY08_18990	COG0515	serine threonine protein kinase
PFY08_18995	COG0631	protein serine/threonine phosphatase activity
PFY08_19005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PFY08_19005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PFY08_19020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFY08_19025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFY08_19045	COG1561	YicC-like family, N-terminal region
PFY08_19050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PFY08_19060	COG0006	proline dipeptidase activity
PFY08_19070	COG3069	C4-dicarboxylate transmembrane transporter activity
PFY08_19135	COG0564	pseudouridine synthase activity
PFY08_19155	COG3599	regulation of cell shape
PFY08_19160	COG2302	S4 RNA-binding domain
PFY08_19165	COG0762	integral membrane protein
PFY08_19175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PFY08_19185	COG1873	PFAM PRC-barrel domain
PFY08_19190	COG1191	sigma factor activity
PFY08_19195	COG1191	sigma factor activity
PFY08_19205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PFY08_19210	COG0849	cell division
PFY08_19230	COG0772	Belongs to the SEDS family
PFY08_19250	COG0768	penicillin binding
PFY08_19255	COG0768	penicillin binding
PFY08_19275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFY08_19290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PFY08_19295	COG1399	metal-binding, possibly nucleic acid-binding protein
PFY08_19305	COG3480	Lon protease (S16) C-terminal proteolytic domain
PFY08_19310	COG1752	Esterase of the alpha-beta hydrolase superfamily
PFY08_19315	COG3314	Sporulation integral membrane protein YlbJ
PFY08_19325	COG0742	ribosomal rna small subunit methyltransferase
PFY08_19340	COG3679	Belongs to the UPF0342 family
PFY08_19345	COG0406	alpha-ribazole phosphatase activity
PFY08_19360	COG2340	Cysteine-rich secretory protein family
PFY08_19375	COG3336	cytochrome c oxidase
PFY08_19410	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PFY08_19415	COG0772	Belongs to the SEDS family
PFY08_19425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PFY08_19430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PFY08_19440	COG4896	Protein conserved in bacteria
PFY08_19455	COG1217	gtp-binding protein TYPA
PFY08_19465	COG0483	inositol monophosphate 1-phosphatase activity
PFY08_19485	COG1982	Orn Lys Arg decarboxylase major
PFY08_19535	COG0022	dehydrogenase e1 component
PFY08_19540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PFY08_19555	COG0561	phosphatase activity
PFY08_19565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFY08_19570	COG0569	domain protein
PFY08_19590	COG0583	DNA-binding transcription factor activity
PFY08_19595	COG0517	IMP dehydrogenase activity
PFY08_19605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
PFY08_19615	COG4703	Protein of unknown function (DUF1797)
PFY08_19630	COG2200	EAL domain
PFY08_19635	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_19640	COG1408	metallophosphoesterase
PFY08_19685	COG2814	Major facilitator Superfamily
PFY08_19705	COG3209	COG3209 Rhs family protein
PFY08_19715	COG2205	protein histidine kinase activity
PFY08_19725	COG0436	Aminotransferase
PFY08_19730	COG1609	Transcriptional regulator
PFY08_19735	COG3833	ABC-type maltose transport systems, permease component
PFY08_19740	COG1175	transmembrane transport
PFY08_19745	COG2182	Extracellular solute-binding protein
PFY08_19755	COG0366	Alpha amylase catalytic
PFY08_19760	COG3842	ATPase activity
PFY08_19800	COG0183	Belongs to the thiolase family
PFY08_19835	COG1695	Transcriptional regulator
PFY08_19840	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_19860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PFY08_19865	COG0436	Aminotransferase
PFY08_19900	COG2084	Dehydrogenase
PFY08_19910	COG2199	diguanylate cyclase activity
PFY08_19915	COG0778	Nitroreductase
PFY08_19940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PFY08_19940	COG2190	(PTS) system
PFY08_19940	COG1263	PTS System
PFY08_19945	COG3711	transcriptional antiterminator
PFY08_19955	COG2188	Transcriptional regulator
PFY08_19965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFY08_19990	COG1547	Domain of unknown function (DUF309)
PFY08_19995	COG0456	acetyltransferase
PFY08_20000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PFY08_20005	COG4086	secreted protein
PFY08_20010	COG0561	phosphatase activity
PFY08_20015	COG0697	spore germination
PFY08_20030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFY08_20055	COG0733	neurotransmitter:sodium symporter activity
PFY08_20075	COG1686	Belongs to the peptidase S11 family
PFY08_20080	COG1725	Transcriptional regulator
PFY08_20085	COG1131	(ABC) transporter
PFY08_20105	COG1846	Transcriptional regulator
PFY08_20120	COG0598	Magnesium transport protein CorA
PFY08_20145	COG4974	Belongs to the 'phage' integrase family
PFY08_20155	COG0735	belongs to the Fur family
PFY08_20160	COG1300	Membrane
PFY08_20180	COG0667	Aldo Keto reductase
PFY08_20185	COG0656	L-ascorbic acid biosynthetic process
PFY08_20190	COG0456	acetyltransferase
PFY08_20190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFY08_20200	COG1525	nuclease
PFY08_20200	COG4085	toxin activity
PFY08_20200	COG0737	Belongs to the 5'-nucleotidase family
PFY08_20210	COG0596	Alpha beta hydrolase
PFY08_20215	COG2056	Na+-H+ antiporter family
PFY08_20220	COG1609	Transcriptional regulator
PFY08_20225	COG0456	acetyltransferase
PFY08_20230	COG1073	alpha beta
PFY08_20245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFY08_20245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PFY08_20250	COG0307	riboflavin synthase, alpha
PFY08_20280	COG2226	methyltransferase
PFY08_20280	COG1073	alpha beta
PFY08_20295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PFY08_20305	COG1757	Na H antiporter
PFY08_20310	COG0737	Belongs to the 5'-nucleotidase family
PFY08_20320	COG1522	sequence-specific DNA binding
PFY08_20365	COG0300	oxidoreductase activity
PFY08_20370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_20375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFY08_20380	COG1760	l-serine dehydratase
PFY08_20385	COG1760	l-serine dehydratase
PFY08_20415	COG1285	pathogenesis
PFY08_20425	COG2195	Cleaves the N-terminal amino acid of tripeptides
PFY08_20430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_20445	COG1376	ErfK ybiS ycfS ynhG family protein
PFY08_20450	COG4129	membrane
PFY08_20455	COG1126	abc transporter atp-binding protein
PFY08_20460	COG0765	amino acid transport
PFY08_20465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PFY08_20485	COG2323	membrane
PFY08_20490	COG0772	Belongs to the SEDS family
PFY08_20495	COG0508	dehydrogenase complex catalyzes the overall conversion of
PFY08_20500	COG0022	dehydrogenase e1 component
PFY08_20505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PFY08_20510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PFY08_20525	COG0280	phosphate acetyltransferase
PFY08_20530	COG3290	protein histidine kinase activity
PFY08_20530	COG3829	transcription factor binding
PFY08_20540	COG0584	glycerophosphoryl diester phosphodiesterase
PFY08_20545	COG3093	addiction module antidote protein HigA
PFY08_20560	COG0750	zinc metalloprotease
PFY08_20565	COG0497	DNA recombination
PFY08_20575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PFY08_20585	COG0142	geranyltranstransferase activity
PFY08_20610	COG1302	Protein conserved in bacteria
PFY08_20615	COG0439	Biotin carboxylase
PFY08_20620	COG0511	ligase activity, forming carbon-carbon bonds
PFY08_20665	COG3854	ATPases associated with a variety of cellular activities
PFY08_20690	COG0006	proline dipeptidase activity
PFY08_20705	COG3872	metal-dependent enzyme
PFY08_20715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PFY08_20750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_20760	COG1609	Transcriptional regulator
PFY08_20770	COG2076	Multidrug Resistance protein
PFY08_20775	COG2076	Multidrug Resistance protein
PFY08_20810	COG1131	(ABC) transporter
PFY08_20815	COG1725	Transcriptional regulator
PFY08_20845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PFY08_20915	COG1459	type II secretion system
PFY08_20920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PFY08_20975	COG1410	methionine synthase
PFY08_20975	COG0646	methionine synthase
PFY08_20980	COG0646	methionine synthase
PFY08_20980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PFY08_20985	COG0626	cystathionine gamma-synthase activity
PFY08_20990	COG0626	cystathionine gamma-synthase activity
PFY08_21010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_21020	COG1940	carbohydrate kinase activity
PFY08_21025	COG4483	Protein conserved in bacteria
PFY08_21030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PFY08_21035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PFY08_21040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PFY08_21045	COG0704	Plays a role in the regulation of phosphate uptake
PFY08_21055	COG0573	inorganic phosphate transmembrane transporter activity
PFY08_21060	COG0573	inorganic phosphate transmembrane transporter activity
PFY08_21065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PFY08_21070	COG0768	penicillin binding
PFY08_21075	COG0477	Major facilitator Superfamily
PFY08_21080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PFY08_21090	COG5521	maltodextrose utilization protein MalA
PFY08_21105	COG0735	belongs to the Fur family
PFY08_21110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PFY08_21115	COG1121	(ABC) transporter
PFY08_21120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_21150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PFY08_21155	COG2384	SAM-dependent methyltransferase
PFY08_21165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PFY08_21170	COG0358	DNA primase activity
PFY08_21185	COG0517	IMP dehydrogenase activity
PFY08_21200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PFY08_21205	COG0295	cytidine deaminase activity
PFY08_21210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PFY08_21220	COG1480	7TM receptor with intracellular HD hydrolase
PFY08_21225	COG1702	phosphate starvation-inducible protein PhoH
PFY08_21240	COG1610	YqeY-like protein
PFY08_21245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PFY08_21250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PFY08_21255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PFY08_21285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PFY08_21290	COG1733	regulation of RNA biosynthetic process
PFY08_21315	COG1466	dna polymerase III delta subunit
PFY08_21325	COG0658	competence protein
PFY08_21325	COG2333	competence protein COMEC
PFY08_21330	COG2131	deaminase
PFY08_21335	COG1555	photosystem II stabilization
PFY08_21335	COG1596	polysaccharide export
PFY08_21340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFY08_21345	COG2226	methyltransferase
PFY08_21350	COG0799	negative regulation of ribosome biogenesis
PFY08_21355	COG1713	HD superfamily hydrolase involved in NAD metabolism
PFY08_21365	COG1534	Rna-binding protein
PFY08_21375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PFY08_21380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
PFY08_21415	COG0778	Nitroreductase
PFY08_21420	COG2357	RelA SpoT domain protein
PFY08_21430	COG1785	Belongs to the alkaline phosphatase family
PFY08_21440	COG2267	carboxylic ester hydrolase activity
PFY08_21475	COG1404	Belongs to the peptidase S8 family
PFY08_21480	COG3186	Phenylalanine-4-hydroxylase
PFY08_21490	COG2514	catechol 2,3-dioxygenase activity
PFY08_21495	COG2259	Doxx family
PFY08_21535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PFY08_21550	COG1012	belongs to the aldehyde dehydrogenase family
PFY08_21550	COG1454	alcohol dehydrogenase
PFY08_21555	COG0626	cystathionine gamma-synthase activity
PFY08_21560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PFY08_21585	COG0768	penicillin binding
PFY08_21605	COG0826	peptidase U32
PFY08_21610	COG0826	peptidase U32
PFY08_21615	COG4122	O-methyltransferase activity
PFY08_21620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PFY08_21650	COG0628	permease
PFY08_21670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PFY08_21685	COG1104	cysteine desulfurase activity
PFY08_21690	COG1959	2 iron, 2 sulfur cluster binding
PFY08_21695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PFY08_21705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PFY08_21730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PFY08_21740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PFY08_21740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PFY08_21745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFY08_21750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PFY08_21750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PFY08_21760	COG2244	polysaccharide biosynthetic process
PFY08_21765	COG2323	membrane
PFY08_21775	COG1862	Preprotein translocase
PFY08_21805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PFY08_21835	COG0157	Belongs to the NadC ModD family
PFY08_21840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PFY08_21845	COG1104	cysteine desulfurase activity
PFY08_21850	COG1827	regulation of RNA biosynthetic process
PFY08_21855	COG2258	MOSC domain
PFY08_21860	COG0077	Prephenate dehydratase
PFY08_21865	COG0577	efflux transmembrane transporter activity
PFY08_21870	COG0577	efflux transmembrane transporter activity
PFY08_21875	COG1136	(ABC) transporter
PFY08_21880	COG5002	protein histidine kinase activity
PFY08_21885	COG0745	RESPONSE REGULATOR receiver
PFY08_21895	COG3290	protein histidine kinase activity
PFY08_21905	COG2868	ribosomal protein
PFY08_21915	COG1530	ribonuclease E activity
PFY08_21920	COG1994	Peptidase M50
PFY08_21925	COG0739	heme binding
PFY08_21930	COG2894	cell division
PFY08_21950	COG1077	Cell shape determining protein MreB Mrl
PFY08_21970	COG0285	dihydrofolate synthase activity
PFY08_21985	COG1388	LysM domain
PFY08_21995	COG0113	porphobilinogen synthase activity
PFY08_22000	COG1587	Uroporphyrinogen-III synthase
PFY08_22010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PFY08_22020	COG1846	Transcriptional regulator
PFY08_22025	COG1764	response to oxidative stress
PFY08_22040	COG0470	DNA polymerase III
PFY08_22040	COG1067	ATP-dependent peptidase activity
PFY08_22085	COG0622	Phosphoesterase
PFY08_22100	COG5401	PFAM Sporulation and spore germination
PFY08_22120	COG1309	transcriptional regulator
PFY08_22130	COG2197	response regulator
PFY08_22135	COG2233	PERMEase
PFY08_22140	COG0402	S-adenosylhomocysteine deaminase activity
PFY08_22145	COG1983	PspC domain protein
PFY08_22150	COG1396	sequence-specific DNA binding
PFY08_22155	COG0697	spore germination
PFY08_22165	COG1959	2 iron, 2 sulfur cluster binding
PFY08_22170	COG1668	transmembrane transport
PFY08_22175	COG4152	abc transporter atp-binding protein
PFY08_22180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
PFY08_22185	COG1360	Flagellar Motor Protein
PFY08_22190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PFY08_22195	COG1876	peptidase activity
PFY08_22200	COG0824	Thioesterase
PFY08_22205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PFY08_22210	COG1053	succinate dehydrogenase
PFY08_22215	COG2009	succinate dehydrogenase
PFY08_22220	COG1719	4-vinyl reductase, 4VR
PFY08_22230	COG3118	belongs to the thioredoxin family
PFY08_22235	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PFY08_22240	COG2086	electron transfer activity
PFY08_22245	COG1024	Enoyl-CoA hydratase
PFY08_22250	COG1309	transcriptional regulator
PFY08_22255	COG0318	PFAM AMP-dependent synthetase and ligase
PFY08_22280	COG2318	DinB family
PFY08_22310	COG1131	(ABC) transporter
PFY08_22315	COG2205	protein histidine kinase activity
PFY08_22320	COG0745	RESPONSE REGULATOR receiver
PFY08_22330	COG4895	conserved protein (DUF2196)
PFY08_22335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PFY08_22345	COG4509	Sortase family
PFY08_22350	COG1120	ATPase activity
PFY08_22365	COG5386	Cell surface protein
PFY08_22375	COG5386	Cell surface protein
PFY08_22380	COG1114	Component of the transport system for branched-chain amino acids
PFY08_22385	COG1187	pseudouridine synthase activity
PFY08_22395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PFY08_22395	COG1796	DNA polymerase
PFY08_22400	COG1286	toxin biosynthetic process
PFY08_22445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFY08_22455	COG1418	mRNA catabolic process
PFY08_22475	COG2814	Major facilitator Superfamily
PFY08_22480	COG1566	PFAM secretion protein HlyD family protein
PFY08_22485	COG1309	transcriptional regulator
PFY08_22490	COG1363	Peptidase, m42
PFY08_22515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFY08_22530	COG1484	DNA-dependent DNA replication
PFY08_22535	COG3611	Membrane attachment protein
PFY08_22545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PFY08_22550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PFY08_22560	COG1971	Probably functions as a manganese efflux pump
PFY08_22570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFY08_22570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFY08_22575	COG5002	protein histidine kinase activity
PFY08_22580	COG0745	RESPONSE REGULATOR receiver
PFY08_22605	COG0538	isocitrate dehydrogenase activity
PFY08_22610	COG0372	Belongs to the citrate synthase family
PFY08_22620	COG0628	permease
PFY08_22625	COG3030	protein affecting phage T7 exclusion by the F plasmid
PFY08_22650	COG1725	Transcriptional regulator
PFY08_22655	COG0281	malic enzyme
PFY08_22660	COG0587	DNA-directed DNA polymerase activity
PFY08_22675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PFY08_22690	COG4109	DRTGG domain
PFY08_22705	COG0006	proline dipeptidase activity
PFY08_22745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_22750	COG0662	Cupin 2, conserved barrel domain protein
PFY08_22765	COG1028	Short-chain dehydrogenase reductase Sdr
PFY08_22770	COG0589	response to stress
PFY08_22810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_22835	COG0827	DNA restriction-modification system
PFY08_22840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PFY08_22845	COG3874	Sporulation protein YtfJ
PFY08_22860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PFY08_22870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PFY08_22885	COG1104	cysteine desulfurase activity
PFY08_22895	COG0583	DNA-binding transcription factor activity
PFY08_22905	COG1309	transcriptional regulator
PFY08_22910	COG1956	GAF domain-containing protein
PFY08_22915	COG0626	cystathionine gamma-synthase activity
PFY08_22940	COG0110	maltose O-acetyltransferase activity
PFY08_22945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PFY08_22950	COG0454	-acetyltransferase
PFY08_22955	COG0517	IMP dehydrogenase activity
PFY08_22960	COG0123	including yeast histone deacetylase and acetoin utilization protein
PFY08_22975	COG0745	RESPONSE REGULATOR receiver
PFY08_22985	COG0666	response to abiotic stimulus
PFY08_23010	COG1609	Transcriptional regulator
PFY08_23015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PFY08_23015	COG1605	Chorismate mutase
PFY08_23020	COG4851	CamS sex pheromone cAM373 precursor
PFY08_23025	COG3118	belongs to the thioredoxin family
PFY08_23035	COG2309	aminopeptidase activity
PFY08_23060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_23080	COG0860	N-Acetylmuramoyl-L-alanine amidase
PFY08_23080	COG1388	LysM domain
PFY08_23090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFY08_23100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PFY08_23105	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PFY08_23110	COG1363	Peptidase, m42
PFY08_23120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_23135	COG0510	thiamine kinase activity
PFY08_23140	COG1523	belongs to the glycosyl hydrolase 13 family
PFY08_23150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PFY08_23155	COG1349	DNA-binding transcription factor activity
PFY08_23160	COG1187	pseudouridine synthase activity
PFY08_23165	COG2244	polysaccharide biosynthetic process
PFY08_23170	COG2081	HI0933 family
PFY08_23175	COG2814	Major facilitator Superfamily
PFY08_23185	COG3832	glyoxalase III activity
PFY08_23205	COG1329	Transcriptional regulator
PFY08_23230	COG0314	molybdopterin synthase activity
PFY08_23235	COG1763	Mo-molybdopterin cofactor biosynthetic process
PFY08_23240	COG0303	'Molybdopterin
PFY08_23250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PFY08_23255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PFY08_23275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFY08_23285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PFY08_23325	COG2814	Major facilitator Superfamily
PFY08_23330	COG0475	glutathione-regulated potassium exporter activity
PFY08_23335	COG0490	domain, Protein
PFY08_23340	COG0582	viral genome integration into host DNA
PFY08_23350	COG1136	(ABC) transporter
PFY08_23370	COG1242	4 iron, 4 sulfur cluster binding
PFY08_23375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PFY08_23380	COG1794	racemase activity, acting on amino acids and derivatives
PFY08_23400	COG2267	carboxylic ester hydrolase activity
PFY08_23405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PFY08_23410	COG0671	phosphoesterase, PA-phosphatase related
PFY08_23415	COG0438	transferase activity, transferring glycosyl groups
PFY08_23435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_23480	COG5002	protein histidine kinase activity
PFY08_23485	COG3852	Histidine kinase
PFY08_23490	COG0753	catalase activity
PFY08_23500	COG2267	carboxylic ester hydrolase activity
PFY08_23505	COG1368	sulfuric ester hydrolase activity
PFY08_23520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PFY08_23525	COG1116	anion transmembrane transporter activity
PFY08_23530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PFY08_23555	COG0494	nUDIX hydrolase
PFY08_23585	COG1854	S-ribosylhomocysteine lyase activity
PFY08_23595	COG0288	reversible hydration of carbon dioxide
PFY08_23600	COG1271	oxidase subunit
PFY08_23605	COG1294	oxidase, subunit
PFY08_23620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_23640	COG1842	Phage shock protein A
PFY08_23670	COG5002	protein histidine kinase activity
PFY08_23675	COG0745	RESPONSE REGULATOR receiver
PFY08_23700	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PFY08_23705	COG1597	lipid kinase activity
PFY08_23725	COG0577	efflux transmembrane transporter activity
PFY08_23730	COG1136	(ABC) transporter
PFY08_23745	COG0586	Pfam SNARE associated Golgi protein
PFY08_23750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PFY08_23755	COG0577	efflux transmembrane transporter activity
PFY08_23760	COG1136	(ABC) transporter
PFY08_23765	COG3708	Transcriptional regulator
PFY08_23765	COG2207	Transcriptional regulator
PFY08_23775	COG5658	integral membrane protein
PFY08_23780	COG0640	Transcriptional regulator
PFY08_23785	COG0745	RESPONSE REGULATOR receiver
PFY08_23790	COG2205	protein histidine kinase activity
PFY08_23795	COG0577	efflux transmembrane transporter activity
PFY08_23800	COG0577	efflux transmembrane transporter activity
PFY08_23805	COG1136	(ABC) transporter
PFY08_23810	COG0577	efflux transmembrane transporter activity
PFY08_23835	COG2188	Transcriptional regulator
PFY08_23855	COG3964	amidohydrolase
PFY08_23885	COG4948	Mandelate Racemase Muconate Lactonizing
PFY08_23895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PFY08_23900	COG0596	Alpha beta hydrolase
PFY08_23910	COG1169	isochorismate synthase
PFY08_23915	COG1575	Belongs to the MenA family. Type 1 subfamily
PFY08_23920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PFY08_23950	COG0058	SHG alpha-glucan phosphorylase activity
PFY08_23960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PFY08_23980	COG1404	Belongs to the peptidase S8 family
PFY08_24080	COG0544	peptidyl-prolyl cis-trans isomerase activity
PFY08_24115	COG1285	pathogenesis
PFY08_24120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PFY08_24135	COG2155	Conserved Protein
PFY08_24140	COG1098	S1 RNA binding domain
PFY08_24145	COG0436	Aminotransferase
PFY08_24150	COG1522	sequence-specific DNA binding
PFY08_24155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFY08_24160	COG2267	carboxylic ester hydrolase activity
PFY08_24170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PFY08_24190	COG5018	Exonuclease
PFY08_24195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PFY08_24215	COG2050	protein possibly involved in aromatic compounds catabolism
PFY08_24225	COG1268	BioY protein
PFY08_24230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PFY08_24235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PFY08_24255	COG2076	Multidrug Resistance protein
PFY08_24260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PFY08_24280	COG2076	Multidrug Resistance protein
PFY08_24285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PFY08_24290	COG3584	3D domain protein
PFY08_24305	COG1252	NADH dehydrogenase
PFY08_24320	COG3708	Transcriptional regulator
PFY08_24335	COG1683	Conserved Protein
PFY08_24435	COG4974	Belongs to the 'phage' integrase family
PFY08_24440	COG0316	Belongs to the HesB IscA family
PFY08_24455	COG1252	NADH dehydrogenase
PFY08_24465	COG2274	protein secretion by the type I secretion system
PFY08_24470	COG0390	transport system, permease component
PFY08_24475	COG2824	Alkylphosphonate utilization operon protein PhnA
PFY08_24500	COG4837	Protein of unknown function (DUF1462)
PFY08_24505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PFY08_24515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PFY08_24520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PFY08_24540	COG1358	cellular component organization or biogenesis
PFY08_24550	COG2249	NAD(P)H dehydrogenase (quinone) activity
PFY08_24555	COG0647	UMP catabolic process
PFY08_24565	COG2445	Protein of unknown function DUF86
PFY08_24570	COG1494	fructose-1,6-bisphosphatase
PFY08_24585	COG4470	Protein conserved in bacteria
PFY08_24595	COG0789	Transcriptional regulator
PFY08_24600	COG4377	Putative membrane peptidase family (DUF2324)
PFY08_24625	COG0739	heme binding
PFY08_24635	COG3377	Domain of unknown function (DUF1805)
PFY08_24640	COG0737	Belongs to the 5'-nucleotidase family
PFY08_24645	COG0719	Fe-S assembly protein
PFY08_24650	COG0822	iron-sulfur transferase activity
PFY08_24655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PFY08_24660	COG0719	Fe-S assembly protein
PFY08_24665	COG0396	ATPase activity
PFY08_24670	COG1464	Belongs to the NlpA lipoprotein family
PFY08_24675	COG1464	Belongs to the NlpA lipoprotein family
PFY08_24680	COG2011	ABC-type metal ion transport system permease component
PFY08_24695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PFY08_24700	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PFY08_24710	COG1393	Belongs to the ArsC family
PFY08_24750	COG1309	transcriptional regulator
PFY08_24755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PFY08_24760	COG1960	acyl-CoA dehydrogenase activity
PFY08_24765	COG0183	Belongs to the thiolase family
PFY08_24770	COG1250	3-hydroxyacyl-CoA dehydrogenase
PFY08_24770	COG1024	Enoyl-CoA hydratase
PFY08_24780	COG1686	Belongs to the peptidase S11 family
PFY08_24795	COG0011	TIGRFAM Protein of
PFY08_24800	COG0840	transmembrane signaling receptor activity
PFY08_24815	COG2814	Major facilitator Superfamily
PFY08_24820	COG0531	amino acid
PFY08_24845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFY08_24880	COG0586	Pfam SNARE associated Golgi protein
PFY08_24890	COG1376	ErfK ybiS ycfS ynhG family protein
PFY08_24895	COG0745	RESPONSE REGULATOR receiver
PFY08_24900	COG5002	protein histidine kinase activity
PFY08_24930	COG0840	transmembrane signaling receptor activity
PFY08_24935	COG2151	metal-sulfur cluster biosynthetic enzyme
PFY08_24940	COG3227	Zinc metalloprotease (Elastase)
PFY08_24945	COG1741	Belongs to the pirin family
PFY08_24960	COG0586	Pfam SNARE associated Golgi protein
PFY08_24965	COG0475	glutathione-regulated potassium exporter activity
PFY08_24970	COG0490	domain, Protein
PFY08_24975	COG1115	amino acid carrier protein
PFY08_24980	COG0783	Belongs to the Dps family
PFY08_24995	COG1611	Belongs to the LOG family
PFY08_25005	COG1528	Iron-storage protein
PFY08_25015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_25020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_25025	COG1115	amino acid carrier protein
PFY08_25030	COG1115	amino acid carrier protein
PFY08_25035	COG2910	NAD(P)H-binding
PFY08_25050	COG0656	L-ascorbic acid biosynthetic process
PFY08_25055	COG2814	Major facilitator Superfamily
PFY08_25060	COG1733	regulation of RNA biosynthetic process
PFY08_25070	COG1252	NADH dehydrogenase
PFY08_25090	COG0840	transmembrane signaling receptor activity
PFY08_25090	COG3290	protein histidine kinase activity
PFY08_25125	COG0488	(ABC) transporter
PFY08_25130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFY08_25205	COG0557	exoribonuclease II activity
PFY08_25210	COG1647	Serine aminopeptidase, S33
PFY08_25215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PFY08_25220	COG1346	cytolysis
PFY08_25255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PFY08_25270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PFY08_25295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFY08_25310	COG2323	membrane
PFY08_25320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PFY08_25330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PFY08_25340	COG1051	belongs to the nudix hydrolase family
PFY08_25350	COG0492	ferredoxin-NADP+ reductase activity
PFY08_25355	COG0457	Tetratricopeptide repeat
PFY08_25360	COG0110	maltose O-acetyltransferase activity
PFY08_25380	COG1950	PFAM Membrane protein of
PFY08_25385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PFY08_25405	COG0789	Transcriptional regulator
PFY08_25425	COG0583	DNA-binding transcription factor activity
PFY08_25435	COG0655	NAD(P)H dehydrogenase (quinone) activity
PFY08_25440	COG0488	(ABC) transporter
PFY08_25450	COG1132	(ABC) transporter
PFY08_25460	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PFY08_25465	COG0583	DNA-binding transcription factor activity
PFY08_25470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFY08_25475	COG0793	Belongs to the peptidase S41A family
PFY08_25475	COG3409	Peptidoglycan-binding domain 1 protein
PFY08_25480	COG2177	Part of the ABC transporter FtsEX involved in
PFY08_25485	COG2884	Cell division ATP-binding protein ftsE
PFY08_25505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PFY08_25510	COG1278	Cold shock
PFY08_25515	COG1040	competence protein
PFY08_25520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PFY08_25525	COG0791	NLP P60 protein
PFY08_25525	COG1388	LysM domain
PFY08_25530	COG1733	regulation of RNA biosynthetic process
PFY08_25535	COG1307	EDD domain protein, DegV family
PFY08_25540	COG1739	Uncharacterized protein family UPF0029
PFY08_25545	COG1316	TRANSCRIPTIONal
PFY08_25550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PFY08_25555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PFY08_25560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PFY08_25570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PFY08_25570	COG3933	PFAM sigma-54 factor interaction domain-containing protein
PFY08_25590	COG1486	melibiose metabolic process
PFY08_25595	COG1447	Phosphotransferase system cellobiose-specific component IIA
PFY08_25600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PFY08_25620	COG1447	Phosphotransferase system cellobiose-specific component IIA
PFY08_25630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PFY08_25635	COG1301	dicarboxylic acid transport
PFY08_25650	COG1511	domain protein
PFY08_25655	COG0583	DNA-binding transcription factor activity
PFY08_25660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PFY08_25670	COG1271	oxidase subunit
PFY08_25675	COG1294	oxidase, subunit
PFY08_25680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PFY08_25710	COG1620	l-lactate permease
PFY08_25720	COG2389	metal-binding protein
PFY08_25730	COG1368	sulfuric ester hydrolase activity
PFY08_25745	COG1388	LysM domain
PFY08_25745	COG0791	NLP P60 protein
PFY08_25750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PFY08_25760	COG1215	transferase activity, transferring glycosyl groups
PFY08_25765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PFY08_25770	COG3584	3D domain protein
PFY08_25770	COG1388	LysM domain
PFY08_25795	COG4715	Zinc finger, swim domain protein
PFY08_25800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PFY08_25840	COG0577	efflux transmembrane transporter activity
PFY08_25845	COG1136	(ABC) transporter
PFY08_25880	COG5002	protein histidine kinase activity
PFY08_25885	COG0745	RESPONSE REGULATOR receiver
PFY08_25895	COG1316	TRANSCRIPTIONal
PFY08_25900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PFY08_25905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PFY08_25910	COG1215	transferase activity, transferring glycosyl groups
PFY08_25940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PFY08_25945	COG4464	protein tyrosine phosphatase activity
PFY08_25950	COG0489	protein tyrosine kinase activity
PFY08_25955	COG3944	biosynthesis protein
PFY08_25965	COG0489	protein tyrosine kinase activity
PFY08_25980	COG1609	Transcriptional regulator
PFY08_25990	COG0739	heme binding
PFY08_26005	COG4555	ABC transporter
PFY08_26010	COG2385	sporulation resulting in formation of a cellular spore
PFY08_26025	COG4836	Membrane
PFY08_26030	COG1007	ATP synthesis coupled electron transport
PFY08_26035	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PFY08_26040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PFY08_26050	COG0839	Belongs to the complex I subunit 6 family
PFY08_26070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PFY08_26085	COG5001	Diguanylate cyclase
PFY08_26085	COG3300	MHYT domain
PFY08_26135	COG0356	it plays a direct role in the translocation of protons across the membrane
PFY08_26170	COG0698	ribose 5-phosphate isomerase
PFY08_26185	COG2259	Doxx family
PFY08_26190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PFY08_26210	COG0009	L-threonylcarbamoyladenylate synthase
PFY08_26245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PFY08_26250	COG1494	fructose-1,6-bisphosphatase
PFY08_26270	COG4821	SIS domain
PFY08_26290	COG1960	acyl-CoA dehydrogenase activity
PFY08_26295	COG1960	acyl-CoA dehydrogenase activity
PFY08_26300	COG1250	3-hydroxyacyl-CoA dehydrogenase
PFY08_26305	COG0183	Belongs to the thiolase family
PFY08_26310	COG0247	lactate metabolic process
PFY08_26310	COG2181	nitrate reductase activity
PFY08_26315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFY08_26325	COG5001	Diguanylate cyclase
PFY08_26325	COG3300	MHYT domain
PFY08_26340	COG3227	Zinc metalloprotease (Elastase)
PFY08_26345	COG2197	response regulator
PFY08_26350	COG4585	Histidine kinase
PFY08_26355	COG0842	Transport permease protein
PFY08_26360	COG1131	(ABC) transporter
PFY08_26365	COG0024	Methionine aminopeptidase
PFY08_26375	COG2234	aminopeptidase activity
PFY08_26405	COG4506	Protein conserved in bacteria
PFY08_26410	COG1619	proteins homologs of microcin C7 resistance protein MccF
PFY08_26435	COG2814	Major facilitator Superfamily
PFY08_26440	COG0789	Transcriptional regulator
PFY08_26445	COG0584	glycerophosphoryl diester phosphodiesterase
PFY08_26450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PFY08_26460	COG1994	Peptidase M50
PFY08_26470	COG1078	dGTPase activity
PFY08_26475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PFY08_26480	COG1120	ATPase activity
PFY08_26485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_26490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PFY08_26510	COG0280	phosphate acetyltransferase
PFY08_26525	COG3773	Cell wall hydrolase
PFY08_26535	COG2363	Small membrane protein
PFY08_26545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PFY08_26550	COG2233	PERMEase
PFY08_26555	COG0561	phosphatase activity
PFY08_26560	COG2814	Major facilitator Superfamily
PFY08_26570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PFY08_26575	COG1131	(ABC) transporter
PFY08_26580	COG2755	lipolytic protein G-D-S-L family
PFY08_26585	COG1609	Transcriptional regulator
PFY08_26595	COG0460	homoserine dehydrogenase
PFY08_26605	COG2873	o-acetylhomoserine
PFY08_26615	COG1011	Hydrolase
PFY08_26620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PFY08_26630	COG2197	response regulator
PFY08_26635	COG2203	Gaf domain
PFY08_26635	COG4585	Histidine kinase
PFY08_26640	COG0351	phosphomethylpyrimidine kinase
PFY08_26645	COG3706	GGDEF domain
PFY08_26650	COG2879	small protein
PFY08_26655	COG1966	Carbon starvation protein
PFY08_26660	COG3279	Response regulator of the LytR AlgR family
PFY08_26665	COG0477	Major facilitator Superfamily
PFY08_26675	COG0438	transferase activity, transferring glycosyl groups
PFY08_26690	COG0840	transmembrane signaling receptor activity
PFY08_26700	COG1607	acyl-coa hydrolase
PFY08_26710	COG1216	Glycosyl transferase, family 2
PFY08_26725	COG0463	Glycosyl transferase, family 2
PFY08_26730	COG0488	(ABC) transporter
PFY08_26745	COG1309	transcriptional regulator
PFY08_26750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PFY08_26755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFY08_26765	COG0628	permease
PFY08_26790	COG2814	Major facilitator Superfamily
PFY08_26795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PFY08_26800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PFY08_26820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PFY08_26825	COG1272	protein, Hemolysin III
PFY08_26845	COG1164	Oligoendopeptidase f
PFY08_26855	COG5002	protein histidine kinase activity
PFY08_26870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PFY08_26875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PFY08_26880	COG4853	Protein conserved in bacteria
PFY08_26890	COG5002	protein histidine kinase activity
PFY08_26895	COG0745	RESPONSE REGULATOR receiver
PFY08_26925	COG0305	Participates in initiation and elongation during chromosome replication
PFY08_26935	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PFY08_26940	COG4241	membrane
PFY08_26960	COG0012	GTP binding
PFY08_26965	COG4481	Protein conserved in bacteria
PFY08_26970	COG0668	transmembrane transport
PFY08_26980	COG1475	DNA binding
PFY08_26985	COG1192	Involved in chromosome partitioning
PFY08_27010	COG1847	R3H domain protein
PFY08_27025	COG0230	Belongs to the bacterial ribosomal protein bL34 family