locus-tag class description BCQ_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCQ_0003 ENOG410848D S4 domain protein YaaA BCQ_0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCQ_0014 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BCQ_0021 ENOG4105ZMH deoxynucleoside kinase BCQ_0023 ENOG4105GTG Isochorismatase BCQ_0024 ENOG4108Z6B deaminase BCQ_0025 ENOG4105C6E dna polymerase iii BCQ_0026 ENOG4105C6E dna polymerase iii BCQ_0030 ENOG41067KS pro-sigma K processing BCQ_0036 ENOG4105CXN decarboxylase BCQ_0038 ENOG4105FA2 dna polymerase iii BCQ_0039 ENOG4105MA4 psp1 domain protein BCQ_0041 ENOG41060K3 Methyltransferase BCQ_0043 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BCQ_0044 ENOG4105KRN Transcriptional regulator, abrb family BCQ_0046 ENOG4105F8V Hydrolase, tatD family BCQ_0047 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BCQ_0049 ENOG4105XFA sporulation peptidase YabG BCQ_0050 ENOG4105W42 Veg protein BCQ_0053 ENOG4105DFT pur operon repressor BCQ_0054 ENOG4105KME endoribonuclease L-psp BCQ_0057 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BCQ_0060 ENOG4108JA2 transcriptioN-repair coupling factor BCQ_0061 ENOG4108M14 stage v sporulation protein t BCQ_0063 ENOG4108IY2 MazG family BCQ_0064 ENOG41082I2 s4 domain protein BCQ_0065 ENOG4105VYY sporulation protein yabp BCQ_0068 ENOG41060GV RNA binding s1 domain protein BCQ_0073 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCQ_0074 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BCQ_0077 ENOG4105C6T cysteine synthase BCQ_0078 ENOG4105CRQ synthase (Component I) BCQ_0079 ENOG4105DDQ anthranilate synthase BCQ_0080 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BCQ_0081 ENOG4105EEI dihydropteroate synthase BCQ_0082 ENOG4105KRF dihydroneopterin aldolase BCQ_0083 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BCQ_0085 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BCQ_0093 ENOG4108Z0C Uvrb UvrC protein BCQ_0096 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BCQ_0098 ENOG4105CTP PilT protein domain protein BCQ_0102 ENOG4105D7W serine acetyltransferase BCQ_0105 ENOG4105C2N RNA methyltransferase TrmH family group 3 BCQ_0106 ENOG4105M0M Tetracycline resistance protein BCQ_0107 ENOG4105QIV RNA polymerase BCQ_0109 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BCQ_0114 ENOG4107Y49 methyltransferase BCQ_0117 ENOG4105XPM ribosomal protein BCQ_0138 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BCQ_0143 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCQ_0145 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCQ_0147 ENOG41067V7 50S ribosomal protein L36 BCQ_0153 ENOG4108JJB ABC transporter BCQ_0154 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCQ_0160 ENOG4105D1F ATP-binding protein BCQ_0163 ENOG4108NMV polysaccharide deacetylase BCQ_0180 ENOG4105C8B TIGR00159 family BCQ_0181 ENOG4107U5W ybbr family BCQ_0184 ENOG4108VQT Alpha beta hydrolase fold protein BCQ_0186 ENOG4105CMG Carbohydrate kinase BCQ_0188 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BCQ_0195 ENOG4108PSK reductase BCQ_0196 ENOG4108UMI ABC transporter, permease BCQ_0198 ENOG4105D01 (LipO)protein BCQ_0199 ENOG4105EE1 crotonyl-CoA reductase BCQ_0201 ENOG4105IQ5 FAD linked oxidase domain protein BCQ_0204 ENOG4105C2C drug resistance transporter, Bcr CflA BCQ_0208 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCQ_0209 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCQ_0210 ENOG4105C3U ABC transporter BCQ_0211 ENOG4108JQ7 (ABC) transporter BCQ_0215 ENOG4105U5Y Transcriptional regulator BCQ_0217 ENOG4108J59 Extracellular solute-binding protein, family 5 BCQ_0218 ENOG4108J59 Extracellular solute-binding protein, family 5 BCQ_0220 ENOG4105II7 pyrroline-5-carboxylate reductase BCQ_0221 ENOG4107XDY Nicotinamide Mononucleotide Transporter BCQ_0223 ENOG4105E0C molybdate abc transporter BCQ_0224 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCQ_0225 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BCQ_0233 ENOG4105F6E Acyl-transferase BCQ_0236 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCQ_0238 ENOG4108RE7 deoxyribonuclease BCQ_0239 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BCQ_0244 ENOG4105C5H ABC transporter BCQ_0246 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BCQ_0247 ENOG4105DEF Extracellular solute-binding protein, family 5 BCQ_0249 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCQ_0250 ENOG4105C3U ABC transporter BCQ_0251 ENOG4108JQ7 (ABC) transporter BCQ_0252 ENOG410667J hydrolase BCQ_0256 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BCQ_0257 ENOG4105ERH Fumarylacetoacetate hydrolase BCQ_0259 ENOG4105CUB amino acid BCQ_0260 ENOG4108SC4 )-transporter BCQ_0261 ENOG4105CPF Cell wall formation (By similarity) BCQ_0262 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCQ_0267 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BCQ_0268 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCQ_0270 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BCQ_0290 ENOG4105K8N protein family UPF0079, ATPase BCQ_0291 ENOG41072GX Peptidase M22 Glycoprotease BCQ_0292 ENOG410801F ribosomal-protein-alanine acetyltransferase BCQ_0294 ENOG4105C5H ABC transporter BCQ_0296 ENOG4108TYN CAAX amino terminal protease family protein BCQ_0300 ENOG4105C7N Xanthine uracil vitamin C permease BCQ_0302 ENOG4105BZU Histidine kinase BCQ_0315 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCQ_0324 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCQ_0331 ENOG4105SX7 Transporter BCQ_0333 ENOG4105DQ6 Transposase BCQ_0340 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BCQ_0341 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BCQ_0342 ENOG4105C83 adenylosuccinate lyase BCQ_0344 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BCQ_0349 ENOG4108V3E phosphoribosylglycinamide formyltransferase BCQ_0351 ENOG4105C12 Phosphoribosylglycinamide synthetase BCQ_0356 ENOG4105C4R Atp-dependent dna helicase BCQ_0362 ENOG4108W2Y isochorismatase BCQ_0364 ENOG4108UMI ABC transporter, permease BCQ_0365 ENOG4105D01 (LipO)protein BCQ_0368 ENOG410834F Transcriptional regulator BCQ_0369 ENOG4107I77 yiaA/B two helix domain BCQ_0373 ENOG4105CBD Diacylglycerol kinase BCQ_0374 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCQ_0375 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BCQ_0376 ENOG4108JPW Aminotransferase BCQ_0378 ENOG4105C26 Dehydrogenase BCQ_0379 ENOG4105KPY Small multidrug resistance protein BCQ_0382 ENOG4105D9N nucleoside BCQ_0383 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BCQ_0385 ENOG4105BZU Histidine kinase BCQ_0388 ENOG4108W15 Protein of unknown function (DUF1456) BCQ_0392 ENOG4105DDC Oxidoreductase domain protein BCQ_0393 ENOG4105CQB FAD linked oxidase domain protein BCQ_0394 ENOG4105CWC Acetylornithine deacetylase BCQ_0400 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BCQ_0401 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCQ_0403 ENOG4107Y80 Major Facilitator superfamily BCQ_0406 ENOG4108W15 Protein of unknown function (DUF1456) BCQ_0409 ENOG4105DTQ mandelate racemase muconate lactonizing BCQ_0411 ENOG4105DFD Na H antiporter BCQ_0415 ENOG4105D3R alkyl hydroperoxide reductase BCQ_0416 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BCQ_0418 ENOG4107W7X Aldolase BCQ_0421 ENOG4105EHG Permease protein BCQ_0422 ENOG4105DQ5 transport system permease protein BCQ_0423 ENOG4108V5C ABC transporter BCQ_0427 ENOG4106UIA BCQ_0434 ENOG410756H nucleotidyltransferase BCQ_0435 ENOG4105D2S major facilitator superfamily BCQ_0438 ENOG4107QJZ Glycosyl transferase, family 2 BCQ_0440 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCQ_0441 ENOG4105E5Q amino acid AbC transporter BCQ_0442 ENOG4105EAB amino acid AbC transporter BCQ_0444 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCQ_0446 ENOG4105CI1 PTS System BCQ_0451 ENOG4107RBB ABC transporter, permease BCQ_0452 ENOG4105C19 ABC transporter BCQ_0457 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BCQ_0464 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BCQ_0467 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCQ_0471 ENOG4105C5H ABC transporter BCQ_0477 ENOG41062JF Transcriptional regulator BCQ_0481 ENOG4105DEU major facilitator superfamily BCQ_0487 ENOG4108N0M stress protein BCQ_0488 ENOG4106FN3 tellurium resistance protein BCQ_0489 ENOG4106FN3 tellurium resistance protein BCQ_0490 ENOG4107TS3 membrane protein, TerC BCQ_0491 ENOG4108TTB tellurium resistance protein BCQ_0495 ENOG4105KJF protein tyrosine phosphatase BCQ_0497 ENOG4107U9T Pfam:Ribonuclease_BN BCQ_0498 ENOG4105C59 p-type ATPase BCQ_0499 ENOG4108IPJ Membrane BCQ_0502 ENOG4105C3F Signal peptidase i BCQ_0504 ENOG4107ZTW SNARE associated Golgi BCQ_0507 ENOG410606W general stress protein BCQ_0508 ENOG4105UPD Calcium Proton BCQ_0520 ENOG4108JUB Transcriptional regulator BCQ_0522 ENOG4108IQI permease BCQ_0528 ENOG4105CSV Glutaminase BCQ_0530 ENOG4108A04 Beta-lactamase BCQ_0533 ENOG4105CKK Glycosyl transferase, family 2 BCQ_0534 ENOG4107QQG Dehydrogenase BCQ_0535 ENOG4105C3I Nad-dependent epimerase dehydratase BCQ_0538 ENOG4105F1A Pyruvate formate-lyase BCQ_0542 ENOG4105CI2 imidazolone-5-propionate hydrolase BCQ_0543 ENOG4105ECP epimerase BCQ_0549 ENOG41067AE Membrane-bound metal-dependent hydrolase BCQ_0550 ENOG4105CEN a g-specific adenine glycosylase BCQ_0551 ENOG4106BXE BCQ_0556 ENOG4105BZ1 (ABC) transporter BCQ_0557 ENOG4107NBY Membrane BCQ_0558 ENOG4105CBC glutamate synthase BCQ_0560 ENOG4108IUW ABC transporter BCQ_0564 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCQ_0565 ENOG4105G5W regulator Fur family BCQ_0587 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCQ_0602 ENOG4108IBT Inherit from COG: transposase BCQ_0607 ENOG4108JQC penicillin-binding protein 1A BCQ_0608 ENOG4108R9S DSBA oxidoreductase BCQ_0611 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BCQ_0613 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BCQ_0614 ENOG4105BZU Histidine kinase BCQ_0616 ENOG4105CYN Serine protein kinase BCQ_0619 ENOG4105C94 Transporter BCQ_0622 ENOG4105DZ6 Band 7 protein BCQ_0624 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BCQ_0625 ENOG4108V9W transcriptional regulatory protein BCQ_0626 ENOG4105D4T Citrate transporter BCQ_0631 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCQ_0632 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCQ_0633 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BCQ_0634 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BCQ_0635 ENOG4105BZ7 extracellular solute-binding protein family 1 BCQ_0636 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BCQ_0637 ENOG4108STX response regulator BCQ_0638 ENOG4105US7 Histidine kinase BCQ_0643 ENOG4108MRH transcriptional regulatory protein BCQ_0645 ENOG4105C6K Malic enzyme BCQ_0647 ENOG4108UZ3 Transporter BCQ_0648 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCQ_0650 ENOG4105BZU Histidine kinase BCQ_0651 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_0653 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCQ_0654 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCQ_0655 ENOG4108JB9 formate dehydrogenase BCQ_0659 ENOG4105CUB amino acid BCQ_0661 ENOG4105C59 p-type ATPase BCQ_0662 ENOG4105DAP Nicotinate phosphoribosyltransferase BCQ_0669 ENOG41073R8 VanW family BCQ_0670 ENOG4108KGH TRANSCRIPTIONal BCQ_0671 ENOG4105D9N nucleoside BCQ_0672 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BCQ_0673 ENOG4105C37 (CBS) domain BCQ_0674 ENOG4108IJ0 Aspartate ammonia-lyase BCQ_0676 ENOG4105DAA L-lactate BCQ_0679 ENOG4105DUX Transporter BCQ_0680 ENOG4108MES Periplasmic binding protein BCQ_0681 ENOG4105DQ5 transport system permease protein BCQ_0682 ENOG4108IHU transport system permease protein BCQ_0683 ENOG4105E0A ABC, transporter BCQ_0684 ENOG4105DMQ Methyltransferase BCQ_0686 ENOG4105EXW epimerase dehydratase BCQ_0687 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BCQ_0689 ENOG4107T89 von Willebrand factor, type A BCQ_0690 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BCQ_0691 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCQ_0694 ENOG4105BZU Histidine kinase BCQ_0695 ENOG4105D5Q Arginine ornithine antiporter BCQ_0696 ENOG4107414 GntR family transcriptional regulator BCQ_0697 ENOG4105C5Y PTS System BCQ_0698 ENOG4105C5Y PTS System BCQ_0699 ENOG4105C5Y PTS System BCQ_0700 ENOG4105CG3 alpha amylase, catalytic region BCQ_0703 ENOG4105E1K spore germination protein BCQ_0705 ENOG4105CRN Aminoglycoside phosphotransferase BCQ_0706 ENOG4105BZG amino acid carrier protein BCQ_0707 ENOG4105CDA abc transporter atp-binding protein BCQ_0708 ENOG4105CT1 (ABC) transporter BCQ_0709 ENOG4105EAD ABC transporter BCQ_0710 ENOG4105DRP amino acid AbC transporter BCQ_0711 ENOG4108IQI permease BCQ_0716 ENOG4105D29 Helix-turn-helix type 11 domain protein BCQ_0717 ENOG4105NAE bifunctional deaminase-reductase domain protein BCQ_0718 ENOG4105BZU Histidine kinase BCQ_0721 ENOG4105CHH sulfate transporter BCQ_0722 ENOG41068KF Universal stress protein BCQ_0726 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCQ_0727 ENOG4108JQ7 (ABC) transporter BCQ_0729 ENOG4105CXY transporter BCQ_0730 ENOG41067TZ transcriptional regulator, MarR family BCQ_0731 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_0732 ENOG4105ETE Transcriptional regulator (LacI family BCQ_0733 ENOG4108RVA ribokinase BCQ_0735 ENOG4105C2J ABC transporter BCQ_0736 ENOG4105CNN ABC, transporter BCQ_0737 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BCQ_0738 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCQ_0744 ENOG4105D7V transposase BCQ_0751 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCQ_0752 ENOG41069ER domain protein BCQ_0753 ENOG4105VZ8 Transcriptional regulator BCQ_0754 ENOG4107D63 BCQ_0757 ENOG4105DUX Transporter BCQ_0762 ENOG4105C85 amino acid BCQ_0763 ENOG4105C7N Xanthine uracil vitamin C permease BCQ_0767 ENOG4105MA6 gCN5-related N-acetyltransferase BCQ_0771 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCQ_0772 ENOG4105E2S oxidase) subunit II BCQ_0776 ENOG4106CAD Protein of unknown function (DUF3311) BCQ_0777 ENOG4105E1V na solute symporter BCQ_0780 ENOG4108NHD germination protein BCQ_0782 ENOG4105CE1 Ferrous iron transport protein b BCQ_0783 ENOG4105CE1 Ferrous iron transport protein b BCQ_0784 ENOG4105CE1 Ferrous iron transport protein b BCQ_0785 ENOG4105CVA phosphate BCQ_0786 ENOG4105C8U phosphate abc transporter BCQ_0787 ENOG4105E2Z phosphate ABC transporter (Permease BCQ_0813 ENOG41080XQ Signal transduction protein with cbs domains BCQ_0816 ENOG4105ETU transcriptional activator (TenA BCQ_0818 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCQ_0820 ENOG4108VEU Thiamine monophosphate synthase BCQ_0821 ENOG41080HI glycine oxidase BCQ_0824 ENOG4105D06 uba thif-type nad fad binding protein BCQ_0825 ENOG4105DWF phosphomethylpyrimidine kinase BCQ_0834 ENOG4108INS Transcriptional regulator BCQ_0839 ENOG4105C19 ABC transporter BCQ_0841 ENOG4105CNN ABC, transporter BCQ_0842 ENOG4105C2J ABC transporter BCQ_0844 ENOG4105C7N Xanthine uracil vitamin C permease BCQ_0846 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCQ_0853 ENOG4108B31 Spore germination protein BCQ_0857 ENOG4107Y03 Nitroreductase BCQ_0858 ENOG4105ED1 spovr family BCQ_0861 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BCQ_0862 ENOG4105XTG Pfam:DUF156 BCQ_0863 ENOG4105VFE sira family BCQ_0864 ENOG4107TPS domain protein BCQ_0865 ENOG4105VFE sira family BCQ_0866 ENOG4105VFE sira family BCQ_0867 ENOG4105VFE sira family BCQ_0869 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BCQ_0870 ENOG41087NI Sulfite exporter TauE/SafE BCQ_0872 ENOG4108KGH TRANSCRIPTIONal BCQ_0877 ENOG4105EMD TRANSCRIPTIONal BCQ_0878 ENOG4105VCP PTS System BCQ_0879 ENOG4105VZJ PTS System BCQ_0884 ENOG41069ER domain protein BCQ_0885 ENOG4107RBB ABC transporter, permease BCQ_0886 ENOG4105C19 ABC transporter BCQ_0892 ENOG4105WEF catalase BCQ_0899 ENOG4107T5V SNARE associated Golgi BCQ_0905 ENOG4105CUB amino acid BCQ_0906 ENOG4107RWR Sodium hydrogen exchanger BCQ_0908 ENOG4106KNT transcriptional regulator BCQ_0916 ENOG4108YXU transcriptional regulator AsnC family BCQ_0918 ENOG4105KPY Small multidrug resistance protein BCQ_0919 ENOG4105KPY Small multidrug resistance protein BCQ_0924 ENOG4105NF4 modulator of drug activity BCQ_0925 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCQ_0926 ENOG4105E5W Transporter BCQ_0928 ENOG4107RKG DJ-1/PfpI family BCQ_0929 ENOG4105CH6 catalase BCQ_0931 ENOG4105D5Q Arginine ornithine antiporter BCQ_0932 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BCQ_0934 ENOG4105C26 Dehydrogenase BCQ_0935 ENOG4105BZ1 (ABC) transporter BCQ_0936 ENOG4105BZ1 (ABC) transporter BCQ_0938 ENOG4105DRP amino acid AbC transporter BCQ_0939 ENOG4105CDA abc transporter atp-binding protein BCQ_0942 ENOG410839P BCQ_0947 ENOG4105BZU Histidine kinase BCQ_0948 ENOG4105WH1 Two component transcriptional regulator luxr family BCQ_0957 ENOG4107FQX Alpha-acetolactate decarboxylase BCQ_0961 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCQ_0962 ENOG4105D4P Coproporphyrinogen iii oxidase BCQ_0963 ENOG4105IYK transposase BCQ_0964 ENOG4105DQ6 Transposase BCQ_0967 ENOG4105CHH sulfate transporter BCQ_0976 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCQ_0977 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCQ_0981 ENOG4105CGU Enoyl-CoA hydratase BCQ_0984 ENOG4105DER m42 family BCQ_0995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCQ_0996 ENOG4105C3U ABC transporter BCQ_0997 ENOG4108JQ7 (ABC) transporter BCQ_0998 ENOG4105CSH Transporter BCQ_1000 ENOG4108MRH transcriptional regulatory protein BCQ_1021 ENOG4105CDU Replicative dna helicase BCQ_1024 ENOG4105CDU Replicative dna helicase BCQ_1039 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCQ_1042 ENOG4105CMT Dihydroxyacetone kinase BCQ_1044 ENOG4105CMT Dihydroxyacetone kinase BCQ_1050 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BCQ_1066 ENOG4105WN5 stage II sporulation protein BCQ_1068 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_1070 ENOG4108MJI response regulator BCQ_1071 ENOG4105BZU Histidine kinase BCQ_1072 ENOG4105BZU Histidine kinase BCQ_1077 ENOG4105K8R UPF0145 protein BCQ_1087 ENOG4107VRP DNA repair exonuclease BCQ_1088 ENOG4106D4I domain protein BCQ_1090 ENOG4108IND Tetr family transcriptional regulator BCQ_1091 ENOG4105EQ0 Major Facilitator superfamily BCQ_1095 ENOG4108MUZ hydrolase BCQ_1102 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BCQ_1105 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BCQ_1107 ENOG4105EMN RNA polymerase sigma factor BCQ_1109 ENOG4105CNI cell division protein FtsW BCQ_1115 ENOG4105EEM helicase BCQ_1116 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCQ_1120 ENOG4105K59 histidine triad (HIT) protein BCQ_1127 ENOG410905X membrane-flanked domain protein BCQ_1128 ENOG4105CKV Membrane BCQ_1134 ENOG410905X membrane-flanked domain protein BCQ_1135 ENOG4105CKV Membrane BCQ_1136 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BCQ_1137 ENOG4105BZ4 penicillin-binding protein BCQ_1139 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCQ_1140 ENOG4105C1Q protoporphyrinogen oxidase BCQ_1146 ENOG4105ECB domain protein BCQ_1151 ENOG4105D29 Helix-turn-helix type 11 domain protein BCQ_1153 ENOG4108RQ5 Beta-lactamase domain-containing protein BCQ_1154 ENOG4105DF9 Lipoate-protein, ligase BCQ_1156 ENOG4105CEY Amp-dependent synthetase and ligase BCQ_1159 ENOG4105CNA YD repeat protein BCQ_1171 ENOG4105ST3 Transcriptional regulator BCQ_1172 ENOG4105ENX hydrolase BCQ_1173 ENOG4107RN3 metallophosphoesterase BCQ_1175 ENOG4107TVP HD domain protein BCQ_1177 ENOG4108AEY RNA polymerase sigma factor BCQ_1178 ENOG41086D8 Transcriptional regulator BCQ_1181 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCQ_1186 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BCQ_1190 ENOG4105ZU5 s-layer protein BCQ_1191 ENOG4107QP3 malate synthase g BCQ_1194 ENOG4105VEQ Cold shock protein BCQ_1196 ENOG4105XVF Competence transcription factor BCQ_1210 ENOG4105ERH Fumarylacetoacetate hydrolase BCQ_1214 ENOG4105CAQ asparagine synthetase BCQ_1215 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BCQ_1216 ENOG4105CH6 catalase BCQ_1217 ENOG4105BZU Histidine kinase BCQ_1221 ENOG4105QNR S1 RNA binding domain protein BCQ_1222 ENOG4105CNA YD repeat protein BCQ_1224 ENOG4105CNA YD repeat protein BCQ_1228 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCQ_1230 ENOG4107AYK membrAne BCQ_1231 ENOG41073B9 BCQ_1233 ENOG4108KP7 hydrolase BCQ_1235 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BCQ_1240 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BCQ_1241 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BCQ_1244 ENOG4105C31 Tryptophanyl-tRNA synthetase BCQ_1247 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BCQ_1248 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BCQ_1250 ENOG4108JQ7 (ABC) transporter BCQ_1251 ENOG4105UQX Mate efflux family protein BCQ_1256 ENOG4108ZCF integral membrane protein BCQ_1258 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCQ_1260 ENOG4105DPN Oligoendopeptidase f BCQ_1262 ENOG4108Z18 K06886 hemoglobin BCQ_1263 ENOG4105MIX Adenylate cyclase BCQ_1264 ENOG4106EFP UPF0738 protein BCQ_1267 ENOG4105EMS pseudouridine synthase BCQ_1271 ENOG4105K64 Glycosyl transferase, family 2 BCQ_1276 ENOG4107TVC Glycosyl transferase, family 2 BCQ_1280 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BCQ_1281 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BCQ_1283 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BCQ_1298 ENOG4105CK7 Sodium proline symporter BCQ_1299 ENOG4105CRQ synthase (Component I) BCQ_1300 ENOG4105DDQ anthranilate synthase BCQ_1323 ENOG4105C7S Dehydrogenase BCQ_1325 ENOG4105VZ8 Transcriptional regulator BCQ_1345 ENOG4105VTR Integrase BCQ_1348 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BCQ_1350 ENOG4105DZ1 carboxypeptidase BCQ_1351 ENOG4105VFR signal peptidase BCQ_1358 ENOG4105C26 Dehydrogenase BCQ_1360 ENOG4105F38 ABC transporter, permease BCQ_1361 ENOG4105D38 putrescine abc transporter BCQ_1362 ENOG4107RUE extracellular solute-binding protein family 1 BCQ_1364 ENOG4105EYF MMPL domain protein BCQ_1366 ENOG4108YBP pseudouridine synthase BCQ_1368 ENOG4105K4I Scp-like extracellular BCQ_1369 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BCQ_1370 ENOG4105CQB FAD linked oxidase domain protein BCQ_1373 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_1374 ENOG4105BZU Histidine kinase BCQ_1375 ENOG4105JXH GntR family transcriptional regulator BCQ_1379 ENOG4106A3R peptidase BCQ_1381 ENOG4108QTI )-transporter BCQ_1382 ENOG4107TS3 membrane protein, TerC BCQ_1383 ENOG4105CZN Potassium uptake protein BCQ_1384 ENOG410681C small acid-soluble spore protein BCQ_1385 ENOG4108Z7G MaoC domain protein dehydratase BCQ_1389 ENOG4105CHR reductase BCQ_1395 ENOG4105C4Y ABC transporter BCQ_1396 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCQ_1397 ENOG4107RCV ABC transporter, permease BCQ_1401 ENOG4105E98 transcriptional regulator DeoR family BCQ_1403 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BCQ_1405 ENOG4105PXI polysaccharide deacetylase BCQ_1407 ENOG4105BZU Histidine kinase BCQ_1408 ENOG41090MY MarR family Transcriptional regulator BCQ_1410 ENOG4106DF1 BCQ_1412 ENOG4105BZU Histidine kinase BCQ_1414 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BCQ_1415 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BCQ_1423 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BCQ_1424 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCQ_1425 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCQ_1426 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCQ_1428 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BCQ_1429 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCQ_1430 ENOG4105CZV ABC transporter BCQ_1432 ENOG4105CJ1 ABC, transporter BCQ_1433 ENOG4108TU7 Inherit from COG: (ABC) transporter BCQ_1440 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCQ_1441 ENOG4105EA8 2-Nitropropane dioxygenase BCQ_1442 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCQ_1444 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BCQ_1450 ENOG4105NQC Flavodoxin BCQ_1457 ENOG4107QMU Mate efflux family protein BCQ_1463 ENOG4105CZN Potassium uptake protein BCQ_1464 ENOG41063Y9 BCQ_1465 ENOG4105KBJ sporulation protein ytfj BCQ_1469 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCQ_1470 ENOG4105C7K acetolactate synthase BCQ_1471 ENOG4108ZP8 Acetolactate synthase small subunit BCQ_1486 ENOG4107RVV histidinol phosphate phosphatase, hisj family BCQ_1489 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BCQ_1490 ENOG4105E0M Sulfatase BCQ_1492 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BCQ_1496 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BCQ_1497 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BCQ_1499 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCQ_1500 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCQ_1501 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCQ_1502 ENOG4105C8J )-transporter BCQ_1507 ENOG4105DFD Na H antiporter BCQ_1511 ENOG4105ENE Histidine kinase BCQ_1512 ENOG4105WH1 Two component transcriptional regulator luxr family BCQ_1515 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCQ_1524 ENOG4105CJ3 phosphate transporter BCQ_1525 ENOG4107GRR phosphate transport regulator BCQ_1526 ENOG4105BZ4 penicillin-binding protein BCQ_1528 ENOG4105BZU Histidine kinase BCQ_1529 ENOG4105I3N Conserved Protein BCQ_1532 ENOG4105BZU Histidine kinase BCQ_1538 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCQ_1539 ENOG4105DZ1 carboxypeptidase BCQ_1540 ENOG4108JIC nucleoside recognition domain protein BCQ_1542 ENOG4105FE9 pseudouridine synthase BCQ_1544 ENOG4107TWT Cytochrome c biogenesis protein BCQ_1545 ENOG4105CRE cytochrome C BCQ_1546 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_1547 ENOG4105BZU Histidine kinase BCQ_1548 ENOG4108WBT adenosyltransferase BCQ_1549 ENOG41063SB peptidase BCQ_1551 ENOG4108SAX Membrane BCQ_1554 ENOG4105C9U ATP-dependent DNA helicase RecQ BCQ_1555 ENOG4105I7S Abortive infection protein BCQ_1557 ENOG4107RGJ metallophosphoesterase BCQ_1559 ENOG4108S6Z Negative regulator of genetic competence BCQ_1564 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BCQ_1565 ENOG4107RB3 L-asparaginase BCQ_1571 ENOG4105S2F BCQ_1572 ENOG41065D1 BCQ_1578 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BCQ_1581 ENOG4105XXQ heptaprenyl diphosphate synthase component I BCQ_1583 ENOG4105EAH synthase BCQ_1587 ENOG4105CIH Imidazole acetol-phosphate transaminase BCQ_1588 ENOG41068YB TPR repeat-containing protein BCQ_1591 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BCQ_1592 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BCQ_1600 ENOG4108JYZ YitT family BCQ_1601 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BCQ_1604 ENOG4105FJR Lmbe family BCQ_1605 ENOG4105CPK Glycosyl transferase (Group 1 BCQ_1611 ENOG4105DVT helicase BCQ_1612 ENOG4105YAC BCQ_1616 ENOG4105CSM endonuclease III BCQ_1618 ENOG4105BZ4 penicillin-binding protein BCQ_1629 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BCQ_1631 ENOG4105DVT helicase BCQ_1632 ENOG4105CTD carboxy-peptidase BCQ_1634 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BCQ_1636 ENOG4105C2W permease BCQ_1637 ENOG4105DHF Membrane BCQ_1638 ENOG410890F Dynamin family BCQ_1639 ENOG4108W0I acetyltransferase BCQ_1641 ENOG4105KHC sulfurtransferase BCQ_1644 ENOG4106032 Glutathionylspermidine synthase BCQ_1651 ENOG4108SZE gCN5-related N-acetyltransferase BCQ_1655 ENOG41081VK Ribonuclease BCQ_1668 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCQ_1670 ENOG4107RWR Sodium hydrogen exchanger BCQ_1672 ENOG4105CN5 Metallo-Beta-Lactamase BCQ_1673 ENOG4108Z5V transcriptional regulator, merr family BCQ_1675 ENOG4105H67 Protein of unknown function (DUF421) BCQ_1677 ENOG41080C8 DUF218 domain BCQ_1684 ENOG4107Y80 Major Facilitator superfamily BCQ_1689 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BCQ_1691 ENOG4107R0U MotA TolQ exbB proton channel BCQ_1692 ENOG4105ER2 Ompa motb domain protein BCQ_1693 ENOG4107YTP response regulator receiver protein BCQ_1694 ENOG4105CBS Chea signal transduction histidine kinase BCQ_1695 ENOG4105DD5 Flagellar motor switch protein BCQ_1698 ENOG4105BZU Histidine kinase BCQ_1702 ENOG4105E1Q flagellar hook-associated protein BCQ_1703 ENOG4105DTJ flagellar hook-associated protein BCQ_1704 ENOG4105DTS flagellar hook-associated BCQ_1707 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BCQ_1708 ENOG4108ZC9 flagellar basal-body rod protein flgc BCQ_1709 ENOG41075Z6 flagellar hook-basal body complex protein fliE BCQ_1710 ENOG4107U2N Flagellar M-ring protein BCQ_1711 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCQ_1717 ENOG4105BZE flagellar hook protein, FlgE BCQ_1720 ENOG4107R88 Chemotaxis protein (CheV) BCQ_1722 ENOG4105I03 Flagellin BCQ_1724 ENOG4105E4C Lytic transglycosylase catalytic BCQ_1726 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BCQ_1727 ENOG4105DD5 Flagellar motor switch protein BCQ_1729 ENOG4105CN7 Flagellar biosynthetic protein FliP BCQ_1730 ENOG4105VS8 Flagellar biosynthetic protein fliq BCQ_1732 ENOG4105D00 flagellar biosynthetic protein flhB BCQ_1733 ENOG4105D7B Flagellar biosynthesis protein flha BCQ_1734 ENOG4105FZW flagellar biosynthesis regulator FlhF BCQ_1735 ENOG4105KTQ flagellar basal-body rod protein BCQ_1740 ENOG4108RZE Tetr family transcriptional regulator BCQ_1743 ENOG4105KAC Antibiotic biosynthesis monooxygenase BCQ_1747 ENOG4108U4N (sortase) family BCQ_1753 ENOG4105DUM transcriptional regulator, lysR family BCQ_1754 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BCQ_1755 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BCQ_1756 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BCQ_1757 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BCQ_1764 ENOG4105CVJ phosphoglycerate mutase BCQ_1768 ENOG4105K56 Transcriptional regulator BCQ_1770 ENOG4105CAQ asparagine synthetase BCQ_1774 ENOG4105PGM cation diffusion facilitator family transporter BCQ_1776 ENOG4105DRR Transcriptional regulator, GntR family BCQ_1777 ENOG4108UZ3 Transporter BCQ_1779 ENOG4105DFD Na H antiporter BCQ_1780 ENOG4105C9Q fumarate hydratase class II BCQ_1784 ENOG4107QJQ Mate efflux family protein BCQ_1785 ENOG4105EC3 peptidase S51, dipeptidase E BCQ_1794 ENOG4106BRA Membrane BCQ_1801 ENOG4105CJ1 ABC, transporter BCQ_1805 ENOG4105BZU Histidine kinase BCQ_1810 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BCQ_1812 ENOG4108IJ0 Aspartate ammonia-lyase BCQ_1813 ENOG4105C6K Malic enzyme BCQ_1819 ENOG41067QW Transcriptional regulator BCQ_1823 ENOG4105FVX BCQ_1831 ENOG4105CSR polyphosphate kinase 2 BCQ_1832 ENOG4105U3E Transcriptional regulator BCQ_1834 ENOG4105DXI Major Facilitator superfamily BCQ_1837 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCQ_1839 ENOG4105EU0 Major facilitator Superfamily BCQ_1840 ENOG4105C6T cysteine synthase BCQ_1844 ENOG4105C8J )-transporter BCQ_1846 ENOG4105X5K response regulator receiver protein BCQ_1847 ENOG4105H67 Protein of unknown function (DUF421) BCQ_1849 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BCQ_1850 ENOG4105CM2 brancheD-chain amino acid aminotransferase BCQ_1851 ENOG4105C7K acetolactate synthase BCQ_1852 ENOG4108ZP8 Acetolactate synthase small subunit BCQ_1853 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BCQ_1855 ENOG4105C7B Threonine dehydratase BCQ_1859 ENOG4105C6X Major Facilitator BCQ_1860 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BCQ_1862 ENOG4105DY9 regulatoR BCQ_1863 ENOG4105CYC Transferase BCQ_1867 ENOG4105F6J Alpha beta hydrolase fold BCQ_1870 ENOG41068WN BCQ_1871 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCQ_1874 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BCQ_1877 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BCQ_1879 ENOG4105C0X amino acid BCQ_1886 ENOG4107RHR regulatoR BCQ_1888 ENOG4105D9N nucleoside BCQ_1889 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BCQ_1893 ENOG4107RAQ aminopeptidase BCQ_1903 ENOG4108T5E Copper resistance protein BCQ_1904 ENOG4105KTB nuclear export factor GLE1 BCQ_1905 ENOG4105KTB nuclear export factor GLE1 BCQ_1906 ENOG4107RT3 EamA-like transporter family BCQ_1907 ENOG4105GZI Transcriptional regulator BCQ_1908 ENOG4108Z40 Transcriptional regulator BCQ_1909 ENOG4107ZXU DSBA oxidoreductase BCQ_1910 ENOG4108TVJ Nitroreductase BCQ_1912 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCQ_1913 ENOG4106F5Q Membrane BCQ_1914 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BCQ_1916 ENOG4105CKI cobalamin synthesis protein BCQ_1918 ENOG4105C0Z ABC transporter BCQ_1919 ENOG4108IV0 ABC, transporter BCQ_1920 ENOG4105C32 Amino acid ABC transporter (Permease) BCQ_1924 ENOG41090U3 tautomerase BCQ_1928 ENOG4105C4M (Ubiquinol oxidase) subunit I BCQ_1929 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCQ_1930 ENOG4108JJ9 ABC, transporter BCQ_1931 ENOG4108JJ8 (ABC) transporter BCQ_1933 ENOG4105K64 Glycosyl transferase, family 2 BCQ_1935 ENOG4108UT6 Transferase hexapeptide repeat containing protein BCQ_1940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCQ_1946 ENOG4105BZ1 (ABC) transporter BCQ_1947 ENOG4105EFI regulatoR BCQ_1948 ENOG4105BZU Histidine kinase BCQ_1951 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCQ_1952 ENOG4108ZJ4 polysaccharide deacetylase BCQ_1957 ENOG4105D6E homoserine dehydrogenase BCQ_1962 ENOG4108KGH TRANSCRIPTIONal BCQ_1963 ENOG4105BZU Histidine kinase BCQ_1964 ENOG4107VMI polysaccharide deacetylase BCQ_1966 ENOG4105KT7 mgtC SapB transporter BCQ_1967 ENOG4105VRR gCN5-related N-acetyltransferase BCQ_1968 ENOG4105YWU small acid-soluble spore protein BCQ_1970 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BCQ_1971 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCQ_1981 ENOG4105KRN Transcriptional regulator, abrb family BCQ_1985 ENOG4108JP0 extracellular solute-binding protein family 1 BCQ_1986 ENOG4108KB1 transcriptional regulator, arac family BCQ_1987 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BCQ_1988 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BCQ_1989 ENOG4105CT8 Phosphorylase BCQ_1991 ENOG4105DKQ ROK family BCQ_1992 ENOG4105E70 isomerase BCQ_1993 ENOG4105CE4 GlcNAc 6-P deacetylase BCQ_1994 ENOG4105DE4 1-phosphofructokinase BCQ_1995 ENOG4105D2M Aldolase BCQ_1996 ENOG4105ESP cell wall surface anchor family protein BCQ_1997 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BCQ_1998 ENOG4105YVS arsR family transcriptional regulator BCQ_1999 ENOG4105CPC Aldo Keto reductase BCQ_2000 ENOG4107XZQ multidrug resistance protein BCQ_2005 ENOG4105C8Q Methyl-accepting chemotaxis BCQ_2008 ENOG4108K88 Membrane BCQ_2009 ENOG4108WPJ Ferritin-like domain BCQ_2013 ENOG4105DEN Luciferase family BCQ_2016 ENOG4105VMI -acetyltransferase BCQ_2017 ENOG4107QM2 Aldo Keto reductase BCQ_2018 ENOG4105CKI cobalamin synthesis protein BCQ_2020 ENOG4105DSE periplasmic solute binding protein BCQ_2022 ENOG4105K4T epimerase BCQ_2024 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCQ_2033 ENOG4107T5V SNARE associated Golgi BCQ_2036 ENOG4108PJD permease BCQ_2038 ENOG4108S4H thioesterase Superfamily protein BCQ_2039 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCQ_2043 ENOG4105SXS Protein of unknown function (DUF456) BCQ_2044 ENOG4105C37 (CBS) domain BCQ_2048 ENOG4108Z7R Chaperone CsaA BCQ_2050 ENOG4108ZRV stage ii sporulation protein p BCQ_2052 ENOG4108VXD carboxy-peptidase BCQ_2054 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BCQ_2059 ENOG4108X4Q Hydrolase BCQ_2061 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BCQ_2062 ENOG4107RBS Methyltransferase BCQ_2065 ENOG41087PP glycosyltransferase MGT family BCQ_2066 ENOG4108JYZ YitT family BCQ_2067 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BCQ_2074 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BCQ_2079 ENOG4105KBJ sporulation protein ytfj BCQ_2084 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BCQ_2088 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BCQ_2090 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BCQ_2091 ENOG4105EMN RNA polymerase sigma factor BCQ_2094 ENOG4105CNW domain protein BCQ_2096 ENOG4108V06 Glutathione peroxidase BCQ_2099 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCQ_2103 ENOG4108IUE nitrate reductase beta subunit BCQ_2104 ENOG4105R3A Nitrate reductase BCQ_2106 ENOG4107V6Q Cyclic nucleotide-binding domain BCQ_2107 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCQ_2108 ENOG4105D06 uba thif-type nad fad binding protein BCQ_2109 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCQ_2110 ENOG4108ZAF Molybdopterin BCQ_2117 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BCQ_2118 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BCQ_2119 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BCQ_2120 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BCQ_2121 ENOG4108IFG nitrite reductase, (NAD(P)H) BCQ_2122 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BCQ_2129 ENOG4105MCT stage V sporulation protein S BCQ_2134 ENOG4105C5H ABC transporter BCQ_2135 ENOG4105EKQ RNA-directed DNA polymerase BCQ_2136 ENOG4105C5H ABC transporter BCQ_2139 ENOG4108UUM single-stranded DNA-binding protein BCQ_2145 ENOG4107YX5 Pfam:DUF548 BCQ_2152 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BCQ_2153 ENOG4105C5S asparaginyl-tRNA synthetase BCQ_2154 ENOG4105C8J )-transporter BCQ_2158 ENOG4107XGZ Hydrolase BCQ_2159 ENOG4105CY2 Citrate transporter BCQ_2160 ENOG4105C0A alcohol dehydrogenase BCQ_2163 ENOG4105KD7 acetyltransferase BCQ_2164 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BCQ_2169 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BCQ_2172 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BCQ_2176 ENOG4107RVG penicillin-binding protein BCQ_2177 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BCQ_2178 ENOG4105E9Q Acyl-transferase BCQ_2179 ENOG4108UT2 hemolysin iii BCQ_2181 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BCQ_2184 ENOG4108RCR degv family BCQ_2185 ENOG4105E8R UPF0173 metal-dependent hydrolase BCQ_2186 ENOG4108KF3 Electron transport protein SCO1 SenC BCQ_2187 ENOG4107Y70 Heat shock protein BCQ_2188 ENOG4105CAQ asparagine synthetase BCQ_2191 ENOG4108MES Periplasmic binding protein BCQ_2192 ENOG4105F0I Aminotransferase BCQ_2198 ENOG4105D8X mechanosensitive ion channel BCQ_2199 ENOG4105BZU Histidine kinase BCQ_2200 ENOG4105WH1 Two component transcriptional regulator luxr family BCQ_2216 ENOG4108IJ8 ABC transporter BCQ_2217 ENOG4105E90 ABC transporter BCQ_2224 ENOG4105C37 (CBS) domain BCQ_2228 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCQ_2231 ENOG4107S4Y M20 DapE family protein YgeY BCQ_2232 ENOG4108TSC N-acetyltransferase BCQ_2233 ENOG4108JUB Transcriptional regulator BCQ_2234 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BCQ_2242 ENOG4108N23 SpoOM-related protein BCQ_2243 ENOG410841Q phosphoesterase PA-phosphatase related protein BCQ_2245 ENOG4105SZ6 Thioredoxin BCQ_2249 ENOG4108TFU terminase (Small subunit) BCQ_2255 ENOG4108AEY RNA polymerase sigma factor BCQ_2260 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BCQ_2271 ENOG4105BZ4 penicillin-binding protein BCQ_2273 ENOG4105CZM Major Facilitator BCQ_2274 ENOG4105W8X HesB YadR YfhF-family protein BCQ_2276 ENOG4105DXD 2-methylcitrate dehydratase BCQ_2277 ENOG4105CR4 methylisocitrate lyase BCQ_2279 ENOG4105C1G acyl-Coa dehydrogenase BCQ_2280 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCQ_2282 ENOG4105N14 lysine exporter protein LysE YggA BCQ_2283 ENOG4105E39 Enoyl-CoA hydratase BCQ_2286 ENOG4107RFY SbcCD D subunit BCQ_2293 ENOG4105FCD Major Facilitator BCQ_2294 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BCQ_2295 ENOG4105E4F Isochorismate synthase BCQ_2296 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BCQ_2297 ENOG4105WQI isochorismatase BCQ_2298 ENOG4105CEY Amp-dependent synthetase and ligase BCQ_2299 ENOG4105WQT MbtH domain protein BCQ_2300 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_2303 ENOG4105K70 DNA-binding protein BCQ_2307 ENOG4105BZG amino acid carrier protein BCQ_2313 ENOG4105FE9 pseudouridine synthase BCQ_2314 ENOG4105C22 threonyL-tRNA synthetase BCQ_2315 ENOG4105C19 ABC transporter BCQ_2327 ENOG41081I9 integral membrane protein BCQ_2331 ENOG4105EYF MMPL domain protein BCQ_2335 ENOG4105WCN acetyltransferase BCQ_2341 ENOG4105C1Q protoporphyrinogen oxidase BCQ_2343 ENOG41089UC methyltransferase, type 11 BCQ_2344 ENOG41068WN BCQ_2346 ENOG4105VEQ Cold shock protein BCQ_2350 ENOG410667J hydrolase BCQ_2354 ENOG4107V2S Transcriptional regulator BCQ_2355 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCQ_2358 ENOG4105DND Transcriptional regulator BCQ_2359 ENOG4108RPX mosc domain containing protein BCQ_2362 ENOG4105BZ1 (ABC) transporter BCQ_2363 ENOG4105BZ1 (ABC) transporter BCQ_2365 ENOG4108JCI Transcriptional regulator BCQ_2373 ENOG4108KPJ rna polymerase sigma factor BCQ_2380 ENOG4105F32 YngK protein BCQ_2384 ENOG4105RD7 BadF BadG BcrA BcrD BCQ_2386 ENOG4107STF Involved in phosphonate degradation (By similarity) BCQ_2392 ENOG4105C1J atp-dependent rna helicase BCQ_2397 ENOG4108RZE Tetr family transcriptional regulator BCQ_2400 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCQ_2401 ENOG41088CC tellurite resistance protein tehB BCQ_2404 ENOG4107RA9 decarboxylase BCQ_2410 ENOG4105CIN aminoacyl-histidine dipeptidase BCQ_2415 ENOG4107RF6 penicillin-binding protein BCQ_2416 ENOG4107RF6 penicillin-binding protein BCQ_2418 ENOG4105DIN metallophosphoesterase BCQ_2420 ENOG4105CJ1 ABC, transporter BCQ_2422 ENOG4107Z3H Transcriptional regulator, TetR family BCQ_2425 ENOG4105C1G acyl-Coa dehydrogenase BCQ_2426 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCQ_2427 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BCQ_2428 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BCQ_2429 ENOG4105E39 Enoyl-CoA hydratase BCQ_2430 ENOG4107QX3 carboxylase BCQ_2431 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCQ_2433 ENOG4105DBI uridine monophosphokinase BCQ_2438 ENOG4105T9C HD domain BCQ_2440 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BCQ_2456 ENOG41089UC methyltransferase, type 11 BCQ_2464 ENOG4105CPQ Dehydrogenase BCQ_2466 ENOG410900G Protein of unknown function (DUF421) BCQ_2467 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BCQ_2469 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BCQ_2470 ENOG4105DK7 lysyl-tRNA synthetase BCQ_2482 ENOG4105D6E homoserine dehydrogenase BCQ_2485 ENOG4105ETU transcriptional activator (TenA BCQ_2500 ENOG410667J hydrolase BCQ_2501 ENOG4105BZU Histidine kinase BCQ_2502 ENOG4107RF6 penicillin-binding protein BCQ_2509 ENOG4108HGU Histidine kinase BCQ_2511 ENOG4105RHY Pfam:UPF0157 BCQ_2512 ENOG4105CB2 alcohol dehydrogenase BCQ_2513 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BCQ_2514 ENOG4105CJN penicillin-binding protein BCQ_2517 ENOG4105CHR reductase BCQ_2529 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BCQ_2533 ENOG4107Y9U Membrane BCQ_2535 ENOG4105EGD dinuclear metal center protein, YbgI family BCQ_2540 ENOG4105FCD Major Facilitator BCQ_2543 ENOG4105E09 nadh pyrophosphatase BCQ_2544 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BCQ_2545 ENOG4108Z4K mutator MutT protein BCQ_2550 ENOG4108XI2 Domain of unknown function (DUF1963) BCQ_2555 ENOG4105D78 K07001 NTE family protein BCQ_2556 ENOG4105KWG Pfam:DUF1696 BCQ_2563 ENOG4105PKS Excinuclease abc c subunit domain protein BCQ_2570 ENOG4107VFR oxidoreductase BCQ_2575 ENOG4105PAD Hydrolase BCQ_2578 ENOG4108IUM Glycogen debranching enzyme BCQ_2583 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BCQ_2594 ENOG4105MSI germination protein ypeb BCQ_2601 ENOG4107Z3H Transcriptional regulator, TetR family BCQ_2607 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BCQ_2611 ENOG4105E98 transcriptional regulator DeoR family BCQ_2615 ENOG4107QKR Dehydrogenase BCQ_2617 ENOG4107RUY (E1 component), alpha subunit BCQ_2619 ENOG4105E1F short-chain dehydrogenase reductase BCQ_2620 ENOG4105RHY Pfam:UPF0157 BCQ_2623 ENOG4108TIT dATP pyrophosphohydrolase BCQ_2628 ENOG4107SQ8 Glycine betaine BCQ_2629 ENOG4108IJ7 Glycine betaine BCQ_2635 ENOG41082BV acetyltransferase BCQ_2636 ENOG41087PP glycosyltransferase MGT family BCQ_2640 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCQ_2641 ENOG4105MSB protein, conserved in bacteria BCQ_2643 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCQ_2647 ENOG4108Z7F N-acetyltransferase BCQ_2651 ENOG4105EEM helicase BCQ_2655 ENOG4105C9U ATP-dependent DNA helicase RecQ BCQ_2665 ENOG4108M1A Chitin-binding protein BCQ_2669 ENOG4105BZG amino acid carrier protein BCQ_2670 ENOG4105C26 Dehydrogenase BCQ_2671 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCQ_2672 ENOG4105CTU Proline racemase BCQ_2673 ENOG4105CTU Proline racemase BCQ_2674 ENOG41080HI glycine oxidase BCQ_2676 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BCQ_2682 ENOG4107T5V SNARE associated Golgi BCQ_2683 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BCQ_2684 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BCQ_2687 ENOG4105DTQ mandelate racemase muconate lactonizing BCQ_2696 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BCQ_2698 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_2702 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BCQ_2705 ENOG4105DPN Oligoendopeptidase f BCQ_2706 ENOG4105EPR degv family BCQ_2719 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BCQ_2720 ENOG4106K7D Major facilitator family transporter BCQ_2725 ENOG4107BMA Transglycosylase associated protein BCQ_2728 ENOG41089UC methyltransferase, type 11 BCQ_2734 ENOG4105CHM Aminotransferase BCQ_2737 ENOG4108ZMI UPF0477 protein BCQ_2747 ENOG4105C02 permease BCQ_2750 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BCQ_2751 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BCQ_2752 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BCQ_2761 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BCQ_2771 ENOG4107VMI polysaccharide deacetylase BCQ_2773 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BCQ_2775 ENOG4106ETB IIa component BCQ_2776 ENOG4108ZCF integral membrane protein BCQ_2777 ENOG4105E0M Sulfatase BCQ_2778 ENOG4105C5H ABC transporter BCQ_2780 ENOG4105EYF MMPL domain protein BCQ_2781 ENOG41082JN Transcriptional regulator BCQ_2787 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BCQ_2792 ENOG41069ER domain protein BCQ_2796 ENOG4105D4B ABC, transporter BCQ_2798 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BCQ_2800 ENOG4105DKT Transcriptional regulator BCQ_2801 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BCQ_2803 ENOG41061GT Aldolase BCQ_2805 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BCQ_2811 ENOG4105II7 pyrroline-5-carboxylate reductase BCQ_2813 ENOG4107258 Transcriptional regulator BCQ_2815 ENOG4105E0Y RtcB Protein BCQ_2816 ENOG4105ECK Fatty Acid Desaturase BCQ_2818 ENOG4105G6Z alkaline phosphatase BCQ_2820 ENOG4105VMP Transcriptional regulator BCQ_2823 ENOG41090T1 Membrane BCQ_2825 ENOG4108WCX response regulator BCQ_2827 ENOG4105KNA -acetyltransferase BCQ_2831 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCQ_2835 ENOG4105C8Y Acetylornithine aminotransferase BCQ_2837 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BCQ_2841 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BCQ_2847 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BCQ_2849 ENOG4108TVJ Nitroreductase BCQ_2850 ENOG4105FS7 Transcriptional regulator BCQ_2853 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCQ_2857 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCQ_2859 ENOG4105C19 ABC transporter BCQ_2863 ENOG4105C19 ABC transporter BCQ_2868 ENOG4108DMH HTH_ARAC BCQ_2869 ENOG4108XET gCN5-related N-acetyltransferase BCQ_2884 ENOG410635A Membrane BCQ_2886 ENOG4108IQI permease BCQ_2888 ENOG4105F1N DNA alkylation repair BCQ_2898 ENOG4107RF6 penicillin-binding protein BCQ_2906 ENOG4105P4J Allophanate hydrolase, subunit 1 BCQ_2907 ENOG4107258 Transcriptional regulator BCQ_2909 ENOG4106N3A copper homeostasis protein cutc BCQ_2910 ENOG4108ZRV stage ii sporulation protein p BCQ_2911 ENOG4108ZHR arsR family transcriptional regulator BCQ_2913 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_2914 ENOG4105FDT acyl-CoA dehydrogenase BCQ_2918 ENOG4105DWD nucleoside recognition domain protein BCQ_2926 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BCQ_2941 ENOG4105E2A Dehydrogenase BCQ_2943 ENOG4108IJ0 Aspartate ammonia-lyase BCQ_2944 ENOG4105HDK L-asparaginase BCQ_2945 ENOG4108IMY Transcriptional regulator BCQ_2946 ENOG4105DQ6 Transposase BCQ_2947 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BCQ_2948 ENOG4105CUB amino acid BCQ_2949 ENOG4105II7 pyrroline-5-carboxylate reductase BCQ_2950 ENOG4108NHD germination protein BCQ_2951 ENOG4108Q8B Spore germination protein BCQ_2956 ENOG4105CSV Glutaminase BCQ_2962 ENOG4107QJQ Mate efflux family protein BCQ_2963 ENOG4107QTZ amino acid BCQ_2964 ENOG4105CGH 5'-nucleotidase BCQ_2965 ENOG4105CH6 catalase BCQ_2974 ENOG4108606 TspO/MBR family BCQ_2975 ENOG4105CVP deoxyribo-dipyrimidine photolyase BCQ_2980 ENOG4108TWJ NADH dehydrogenase subunit 5 BCQ_2981 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BCQ_2984 ENOG4105E1K spore germination protein BCQ_2986 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCQ_2988 ENOG4105C19 ABC transporter BCQ_2998 ENOG4105DET Rhamnulokinase BCQ_2999 ENOG4105MP9 class II Aldolase BCQ_3001 ENOG4105CNN ABC, transporter BCQ_3003 ENOG4105NWF RbsD or FucU transport BCQ_3004 ENOG4105ETE Transcriptional regulator (LacI family BCQ_3008 ENOG4105D6J arsenicaL-resistance protein BCQ_3009 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BCQ_3010 ENOG41085FC arsR family transcriptional regulator BCQ_3012 ENOG4105NAE bifunctional deaminase-reductase domain protein BCQ_3015 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BCQ_3020 ENOG4107P5I polyketide synthase BCQ_3021 ENOG4108IG5 Transcriptional regulator BCQ_3022 ENOG4105F27 Major Facilitator BCQ_3023 ENOG4105M4P Tetr family transcriptional regulator BCQ_3024 ENOG4105CHR reductase BCQ_3025 ENOG4108YXU transcriptional regulator AsnC family BCQ_3034 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BCQ_3035 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_3043 ENOG4105K6H D-cysteine desulfhydrase BCQ_3045 ENOG4105C88 aminopeptidase BCQ_3048 ENOG4105W1Y Transcriptional regulator BCQ_3049 ENOG4105JQZ Methyltransferase BCQ_3053 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BCQ_3057 ENOG4105BZU Histidine kinase BCQ_3060 ENOG4108U05 Transcriptional regulator BCQ_3061 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BCQ_3063 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BCQ_3064 ENOG4105DJB Major Facilitator Superfamily BCQ_3065 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BCQ_3066 ENOG4107QR9 Iron-sulfur cluster binding protein BCQ_3068 ENOG4106P55 Transcriptional regulator BCQ_3071 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BCQ_3074 ENOG4108JQ1 Dehydrogenase BCQ_3077 ENOG41082W1 Cupin 2, conserved barrel domain protein BCQ_3078 ENOG410874W AraC family transcriptional regulator BCQ_3083 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCQ_3092 ENOG4108ISG Major Facilitator BCQ_3095 ENOG4107MII Sugar-specific transcriptional regulator TrmB BCQ_3096 ENOG4105CZM Major Facilitator BCQ_3100 ENOG4105DA5 (ABC) transporter BCQ_3101 ENOG41069JR BCQ_3103 ENOG4105KPY Small multidrug resistance protein BCQ_3104 ENOG4105KBX Transcriptional regulator, TetR family BCQ_3106 ENOG4105CRW Short chain fatty acid transporter BCQ_3108 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCQ_3115 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BCQ_3123 ENOG4107SWG transcriptional regulator MERR family BCQ_3126 ENOG41067QW Transcriptional regulator BCQ_3129 ENOG4108Z66 YbaK ebsC protein BCQ_3134 ENOG4105KVH Transcriptional regulator BCQ_3135 ENOG4108RCM Nitroreductase BCQ_3139 ENOG4108PSK reductase BCQ_3141 ENOG4105CJ1 ABC, transporter BCQ_3151 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BCQ_3152 ENOG4105DKQ ROK family BCQ_3153 ENOG4108UW5 maltose o-acetyltransferase BCQ_3154 ENOG4105C31 Tryptophanyl-tRNA synthetase BCQ_3161 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BCQ_3163 ENOG4105EV4 Multidrug resistance protein mdtH BCQ_3168 ENOG4105C37 (CBS) domain BCQ_3171 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BCQ_3172 ENOG4105FAW cDP-glucose 4,6-dehydratase BCQ_3178 ENOG4107R5Z Oxidoreductase domain protein BCQ_3180 ENOG4105DDN Pentapeptide repeat-containing protein BCQ_3181 ENOG4105XDF Protein of unknown function (DUF1272) BCQ_3182 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BCQ_3183 ENOG4105CMG Carbohydrate kinase BCQ_3184 ENOG4105C6Z Gluconate BCQ_3185 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BCQ_3188 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BCQ_3190 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BCQ_3193 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BCQ_3196 ENOG4105CV8 reductase BCQ_3197 ENOG4105F27 Major Facilitator BCQ_3200 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BCQ_3201 ENOG4105C44 Serine transporter BCQ_3207 ENOG4105KVH Transcriptional regulator BCQ_3208 ENOG4108TZY GntR Family Transcriptional Regulator BCQ_3209 ENOG4105D9R oxidoreductase BCQ_3210 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BCQ_3211 ENOG4105KVH Transcriptional regulator BCQ_3212 ENOG4105KVH Transcriptional regulator BCQ_3220 ENOG4105JAB phenazine biosynthesis protein, phzf family BCQ_3222 ENOG4105CHR reductase BCQ_3224 ENOG4105KNA -acetyltransferase BCQ_3226 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BCQ_3227 ENOG4105KVH Transcriptional regulator BCQ_3230 ENOG4108ZJ4 polysaccharide deacetylase BCQ_3244 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BCQ_3253 ENOG4105H3G oxidoreductase BCQ_3260 ENOG4105CIS alcohol dehydrogenase BCQ_3272 ENOG4108TN2 lmbE family BCQ_3274 ENOG4107R3E Citrate transporter BCQ_3277 ENOG4108MES Periplasmic binding protein BCQ_3278 ENOG4105EHG Permease protein BCQ_3279 ENOG4105DQ5 transport system permease protein BCQ_3280 ENOG4105NX3 Membrane BCQ_3284 ENOG41068WN BCQ_3285 ENOG4107CUJ Protein of unknown function (DUF2690) BCQ_3287 ENOG4107V2S Transcriptional regulator BCQ_3289 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCQ_3292 ENOG4105C98 muts2 protein BCQ_3293 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BCQ_3294 ENOG4105DPN Oligoendopeptidase f BCQ_3295 ENOG4108A04 Beta-lactamase BCQ_3302 ENOG41082BM Transcriptional regulator, arsr family BCQ_3303 ENOG4105CIS alcohol dehydrogenase BCQ_3309 ENOG4105RHY Pfam:UPF0157 BCQ_3310 ENOG4105C09 Bile acid BCQ_3311 ENOG4105CQB FAD linked oxidase domain protein BCQ_3317 ENOG4105KT7 mgtC SapB transporter BCQ_3320 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCQ_3321 ENOG4105EAB amino acid AbC transporter BCQ_3323 ENOG4108HW4 amino acid AbC transporter BCQ_3324 ENOG41073R8 VanW family BCQ_3326 ENOG4108R1P BCQ_3330 ENOG4105VEQ Cold shock protein BCQ_3337 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BCQ_3341 ENOG410904N short-chain dehydrogenase reductase BCQ_3343 ENOG4106IQC argininosuccinate lyase BCQ_3346 ENOG4108IA2 Sodium pantothenate symporter BCQ_3348 ENOG4105C26 Dehydrogenase BCQ_3349 ENOG4105CHR reductase BCQ_3351 ENOG4105EWU Squalene--hopene cyclase BCQ_3353 ENOG4105FR1 rard protein BCQ_3354 ENOG410696E Membrane BCQ_3357 ENOG4105D1F ATP-binding protein BCQ_3359 ENOG4108ZAF Molybdopterin BCQ_3360 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCQ_3361 ENOG4105D06 uba thif-type nad fad binding protein BCQ_3362 ENOG4105TMB Formate nitrite transporter BCQ_3364 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BCQ_3365 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BCQ_3367 ENOG4108JB9 formate dehydrogenase BCQ_3368 ENOG4105E1K spore germination protein BCQ_3381 ENOG4107QJT sodium dicarboxylate symporter BCQ_3382 ENOG4108KGH TRANSCRIPTIONal BCQ_3384 ENOG4105EMN RNA polymerase sigma factor BCQ_3387 ENOG4105CIG ABC transporter BCQ_3389 ENOG4105D9R oxidoreductase BCQ_3391 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BCQ_3392 ENOG4105K4P CoA-binding domain protein BCQ_3393 ENOG4105C0H protease BCQ_3394 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_3396 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BCQ_3399 ENOG4105W8X HesB YadR YfhF-family protein BCQ_3405 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCQ_3406 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BCQ_3407 ENOG4105BZ1 (ABC) transporter BCQ_3408 ENOG4108I0Z Aconitate hydratase BCQ_3414 ENOG4105E5W Transporter BCQ_3414 ENOG4105E5W Transporter BCQ_3419 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BCQ_3425 ENOG4107F3J Amp-dependent synthetase and ligase BCQ_3426 ENOG4107ZYJ bioY protein BCQ_3427 ENOG4105CEY Amp-dependent synthetase and ligase BCQ_3430 ENOG4108IMY Transcriptional regulator BCQ_3439 ENOG4107AYK membrAne BCQ_3441 ENOG4105BZU Histidine kinase BCQ_3442 ENOG4105FBA Phospholipase Carboxylesterase BCQ_3443 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BCQ_3444 ENOG4105CK7 Sodium proline symporter BCQ_3446 ENOG4105CBC glutamate synthase BCQ_3447 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BCQ_3448 ENOG4108VJ1 Transcriptional regulator (CarD family BCQ_3449 ENOG4108903 Formimidoylglutamase BCQ_3454 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BCQ_3462 ENOG4105EKQ RNA-directed DNA polymerase BCQ_3465 ENOG4107QIV Cytochrome c biogenesis protein BCQ_3467 ENOG4105CH2 amidohydrolase BCQ_3469 ENOG4105CJ1 ABC, transporter BCQ_3471 ENOG4107RSM transcriptional regulator BCQ_3473 ENOG41067MG lrgb family BCQ_3478 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BCQ_3482 ENOG4105BZ1 (ABC) transporter BCQ_3483 ENOG4105BZ1 (ABC) transporter BCQ_3489 ENOG4105D5T phosphonate abc transporter BCQ_3490 ENOG4108HW3 (ABC) transporter BCQ_3491 ENOG4105CGH 5'-nucleotidase BCQ_3493 ENOG4108SVB resolvase BCQ_3497 ENOG4105K7K Transcriptional regulator BCQ_3498 ENOG4105C5F glutamine synthetase BCQ_3499 ENOG4105KV4 Transcriptional regulator BCQ_3500 ENOG4105CXI aluminum resistance protein BCQ_3501 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BCQ_3502 ENOG4105EN6 Membrane BCQ_3504 ENOG4106F1P AAA ATPase, central domain protein BCQ_3511 ENOG41069ER domain protein BCQ_3512 ENOG4105DM4 PTS System BCQ_3513 ENOG4105DE4 1-phosphofructokinase BCQ_3514 ENOG4105E98 transcriptional regulator DeoR family BCQ_3515 ENOG4107QW4 alcohol dehydrogenase BCQ_3516 ENOG4108SJC Membrane BCQ_3519 ENOG4105C85 amino acid BCQ_3522 ENOG4105TMB Formate nitrite transporter BCQ_3523 ENOG4105K70 DNA-binding protein BCQ_3525 ENOG4105C59 p-type ATPase BCQ_3526 ENOG410681U heavy metal transport detoxification protein BCQ_3527 ENOG4105VPX protein, conserved in bacteria BCQ_3529 ENOG4105NIV Esterase BCQ_3530 ENOG4105E0A ABC, transporter BCQ_3535 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BCQ_3536 ENOG4105D03 DNA-3-methyladenine glycosylase II BCQ_3540 ENOG4105BZU Histidine kinase BCQ_3548 ENOG4105F0V Cell wall hydrolase BCQ_3550 ENOG4105E0M Sulfatase BCQ_3551 ENOG410890F Dynamin family BCQ_3553 ENOG4107QHE Choloylglycine hydrolase BCQ_3559 ENOG4105DQU oxidoreductase, subunit beta BCQ_3560 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BCQ_3561 ENOG4108IGT Dipeptidase BCQ_3562 ENOG4105MCT stage V sporulation protein S BCQ_3563 ENOG4105D48 metallophosphoesterase BCQ_3564 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) BCQ_3568 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BCQ_3571 ENOG4105XZV Protein of unknown function (DUF3243) BCQ_3572 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BCQ_3576 ENOG4105UIB (ABC) transporter BCQ_3577 ENOG4108JQ9 ABC transporter BCQ_3578 ENOG4105DIH basic membrane BCQ_3579 ENOG4105FDP GntR family transcriptional regulator BCQ_3580 ENOG4107QZI cell division protein FtsK BCQ_3582 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BCQ_3584 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BCQ_3586 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BCQ_3587 ENOG4108S0H Dipicolinic acid synthetase, b subunit BCQ_3588 ENOG4105E35 Dipicolinate synthase subunit A BCQ_3590 ENOG4105C1V Peptidase, M16 BCQ_3593 ENOG4105DTN riboflavin biosynthesis protein ribF BCQ_3596 ENOG4105W7A Protein of unknown function (DUF503) BCQ_3598 ENOG4105VHM ribosomal protein BCQ_3599 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BCQ_3600 ENOG4105CHV Transcription elongation factor NusA BCQ_3602 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCQ_3605 ENOG4105DZP Membrane-associated zinc metalloprotease BCQ_3607 ENOG4105KNE Phosphatidate cytidylyltransferase BCQ_3616 ENOG4108HE4 integrase family BCQ_3618 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BCQ_3619 ENOG4105C79 DNA protecting protein DprA BCQ_3620 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BCQ_3623 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BCQ_3628 ENOG4105VB6 UPF0109 protein BCQ_3632 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BCQ_3633 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BCQ_3636 ENOG4105CHR reductase BCQ_3637 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BCQ_3640 ENOG4105CB5 ATP-dependent DNA helicase recG BCQ_3641 ENOG4105DP4 dak2 domain fusion protein ylov BCQ_3642 ENOG4108ZAA Alkaline-shock protein BCQ_3644 ENOG4105FJ0 thiamine BCQ_3645 ENOG4105DJV ribulose-phosphate 3-epimerase BCQ_3647 ENOG4105D9P serine threonine protein kinase BCQ_3648 ENOG4108ZF3 Phosphatase BCQ_3650 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BCQ_3652 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCQ_3653 ENOG4105C25 Primosomal protein n' BCQ_3654 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BCQ_3658 ENOG4105DSJ YicC domain protein BCQ_3660 ENOG4105F23 Fibronectin-binding protein BCQ_3661 ENOG4105DC7 peptidase M24 BCQ_3678 ENOG4105C34 Pseudouridine synthase BCQ_3683 ENOG4105DBK s4 domain protein BCQ_3684 ENOG41067XK integral membrane protein BCQ_3686 ENOG4105DFA alanine racemase domain protein BCQ_3687 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BCQ_3688 ENOG4105WR5 sporulation protein, YlmC YmxH family BCQ_3690 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_3692 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BCQ_3693 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BCQ_3694 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BCQ_3697 ENOG4105CNI cell division protein FtsW BCQ_3700 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BCQ_3701 ENOG4105CJN penicillin-binding protein BCQ_3702 ENOG4105CJN penicillin-binding protein BCQ_3703 ENOG41068DC Essential cell division protein (By similarity) BCQ_3710 ENOG4105KNH Nucleic acid-binding protein BCQ_3712 ENOG41063PX domain protein BCQ_3713 ENOG4105D78 K07001 NTE family protein BCQ_3714 ENOG4105H20 Sporulation integral membrane protein YlbJ BCQ_3717 ENOG4106H78 methyltransferase BCQ_3722 ENOG4107TB6 phosphoglycerate mutase BCQ_3725 ENOG4106UY4 Inherit from COG: Scp-like extracellular BCQ_3731 ENOG4105BZ9 Cytochrome C oxidase, subunit I BCQ_3735 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BCQ_3736 ENOG4105CNI cell division protein FtsW BCQ_3739 ENOG4108IAB Phoh family BCQ_3743 ENOG4105QA2 BCQ_3744 ENOG4105CI3 gtp-binding protein typa BCQ_3746 ENOG4105ECY inositol monophosphatase BCQ_3747 ENOG4105ECY inositol monophosphatase BCQ_3751 ENOG4105CXN decarboxylase BCQ_3760 ENOG4105CPP Dehydrogenase, E1 component BCQ_3763 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BCQ_3764 ENOG4108X4Q Hydrolase BCQ_3766 ENOG4105CN5 Metallo-Beta-Lactamase BCQ_3767 ENOG4107ZYR domain protein BCQ_3774 ENOG4108XRC Protein of unknown function (DUF458) BCQ_3777 ENOG4105EPM Diguanylate phosphodiesterase BCQ_3778 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BCQ_3780 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCQ_3781 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BCQ_3783 ENOG4105UIN BCQ_3796 ENOG4108HGU Histidine kinase BCQ_3798 ENOG4105CHM Aminotransferase BCQ_3799 ENOG4105FKQ transcriptional regulator BCQ_3800 ENOG4105EG2 ABC transporter, permease BCQ_3802 ENOG4107FKK extracellular solute-binding protein family 1 BCQ_3804 ENOG4105CG3 alpha amylase, catalytic region BCQ_3812 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BCQ_3813 ENOG4105CHU acetyl-coa acetyltransferase BCQ_3819 ENOG4105K7K Transcriptional regulator BCQ_3820 ENOG4105DTD Dehydrogenase BCQ_3825 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BCQ_3832 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BCQ_3834 ENOG4106TD9 Diguanylate cyclase BCQ_3838 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BCQ_3841 ENOG4105CID antiterminator BCQ_3843 ENOG4105FDP GntR family transcriptional regulator BCQ_3845 ENOG4105CE4 GlcNAc 6-P deacetylase BCQ_3852 ENOG4107ZE5 PPIases accelerate the folding of proteins BCQ_3853 ENOG4105PTM secreted protein BCQ_3854 ENOG4105J7I hydrolase BCQ_3856 ENOG4105G6R Stage v sporulation protein ae BCQ_3858 ENOG4105CZ3 stage V sporulation protein ad BCQ_3859 ENOG41090VF Stage v sporulation protein ac BCQ_3862 ENOG4105C8J )-transporter BCQ_3863 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_3865 ENOG41082AN stage II sporulation protein BCQ_3866 ENOG4105DZ1 carboxypeptidase BCQ_3867 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCQ_3868 ENOG4105DVE abc transporter atp-binding protein BCQ_3875 ENOG4105D7N magnesium and cobalt transport protein CorA BCQ_3880 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCQ_3882 ENOG4105I3K Ferric uptake regulator, Fur family BCQ_3883 ENOG4105MZ9 stage II sporulation protein m BCQ_3887 ENOG4105CPC Aldo Keto reductase BCQ_3889 ENOG4105RHY Pfam:UPF0157 BCQ_3893 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BCQ_3895 ENOG4105ETE Transcriptional regulator (LacI family BCQ_3896 ENOG4108YM7 Gcn5-related n-acetyltransferase BCQ_3899 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BCQ_3900 ENOG4108R6K riboflavin synthase, subunit alpha BCQ_3905 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCQ_3906 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BCQ_3909 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BCQ_3912 ENOG4105DFD Na H antiporter BCQ_3913 ENOG4105CGH 5'-nucleotidase BCQ_3924 ENOG4108IXY short-chain dehydrogenase reductase BCQ_3925 ENOG41069FQ Metallo-beta-lactamase superfamily BCQ_3926 ENOG4105II7 pyrroline-5-carboxylate reductase BCQ_3927 ENOG4105EJQ L-serine dehydratase BCQ_3933 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BCQ_3934 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BCQ_3935 ENOG4105D9U N-acetyltransferase BCQ_3938 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BCQ_3939 ENOG4108QEG Membrane BCQ_3940 ENOG4105CDA abc transporter atp-binding protein BCQ_3941 ENOG4105E5Q amino acid AbC transporter BCQ_3942 ENOG4108HW3 (ABC) transporter BCQ_3945 ENOG4108QY0 Membrane BCQ_3947 ENOG4105C7S Dehydrogenase BCQ_3948 ENOG4105CPP Dehydrogenase, E1 component BCQ_3952 ENOG4107RDP Dehydrogenase BCQ_3954 ENOG4108JUB Transcriptional regulator BCQ_3956 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCQ_3958 ENOG4107QQR Sporulation BCQ_3959 ENOG4105S1Z Stage IV sporulation protein B BCQ_3960 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BCQ_3962 ENOG4105DX0 Hemolysin A BCQ_3964 ENOG4105CTB Polyprenyl synthetase BCQ_3969 ENOG4108ZSR alkaline shock protein BCQ_3970 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BCQ_3975 ENOG410644B Stage III sporulation protein af BCQ_3977 ENOG4105KQ4 Stage iii sporulation protein ad BCQ_3978 ENOG4108CQH stage III sporulation protein AC BCQ_3979 ENOG4105KR5 Stage iii sporulation protein BCQ_3980 ENOG4105CD2 stage iii sporulation protein aa BCQ_3985 ENOG4105DC7 peptidase M24 BCQ_3988 ENOG4105CBJ Metal-dependent enzyme BCQ_3995 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BCQ_3996 ENOG4105WZW rhodanese family BCQ_4000 ENOG41080TC multidrug resistance protein BCQ_4006 ENOG4105CJ1 ABC, transporter BCQ_4007 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BCQ_4013 ENOG4105C0D helicase BCQ_4038 ENOG4105C3R Methionine synthase BCQ_4041 ENOG4105C28 cystathionine BCQ_4042 ENOG4105C28 cystathionine BCQ_4047 ENOG4105C5X domain protein BCQ_4048 ENOG4105DKQ ROK family BCQ_4050 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BCQ_4053 ENOG4108UTW Plays a role in the regulation of phosphate uptake BCQ_4054 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BCQ_4055 ENOG4105E2Z phosphate ABC transporter (Permease BCQ_4056 ENOG4105C8U phosphate abc transporter BCQ_4057 ENOG4105PWN phosphate abc transporter BCQ_4058 ENOG4107RF6 penicillin-binding protein BCQ_4060 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCQ_4065 ENOG4105N80 Ferric uptake regulator, Fur family BCQ_4067 ENOG4105FDK ABC transporter BCQ_4068 ENOG4105FDK ABC transporter BCQ_4069 ENOG4108JYZ YitT family BCQ_4070 ENOG4108JYZ YitT family BCQ_4071 ENOG41069ZM Protein of unknown function (DUF2624) BCQ_4076 ENOG4105EGD dinuclear metal center protein, YbgI family BCQ_4079 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_4080 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BCQ_4086 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BCQ_4087 ENOG4105KG3 cytidine deaminase BCQ_4088 ENOG4107YR5 Diacylglycerol kinase BCQ_4090 ENOG4105CTJ Metal Dependent Phosphohydrolase BCQ_4091 ENOG4105C9A Phoh family BCQ_4094 ENOG4105KTH gatB Yqey BCQ_4096 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BCQ_4097 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BCQ_4103 ENOG4105CSA Coproporphyrinogen iii oxidase BCQ_4104 ENOG4105KVH Transcriptional regulator BCQ_4109 ENOG4105TQK DNA polymerase iii, delta' subunit BCQ_4111 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BCQ_4112 ENOG4108UK2 deaminase BCQ_4113 ENOG4105KQC Competence protein BCQ_4115 ENOG4105DXX methyltransferase BCQ_4117 ENOG4108WF2 Metal Dependent Phosphohydrolase BCQ_4119 ENOG410812S Rna-binding protein BCQ_4121 ENOG4105CQW ribosome biogenesis GTPase YqeH BCQ_4122 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BCQ_4125 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_4131 ENOG4105G6Z alkaline phosphatase BCQ_4133 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BCQ_4134 ENOG4108MUZ hydrolase BCQ_4141 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCQ_4142 ENOG4105MIR Phenylalanine 4-monooxygenase BCQ_4144 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BCQ_4152 ENOG4105S6R Iron-hydroxamate transporter permease subunit BCQ_4153 ENOG4108HUF Transporter BCQ_4155 ENOG4108EKI Dehydrogenase BCQ_4156 ENOG4105C28 cystathionine BCQ_4162 ENOG4107XRG penicillin-binding protein BCQ_4165 ENOG4105CFP Peptidase U32 BCQ_4166 ENOG4105XYU peptidase (U32 family) BCQ_4167 ENOG4108VQJ O-methyltransferase BCQ_4168 ENOG4105HHA aminodeoxychorismate lyase BCQ_4174 ENOG4105C02 permease BCQ_4177 ENOG41060CR BCQ_4178 ENOG4105C7H Helicase, RecD TraA family BCQ_4181 ENOG4105C3J Cysteine desulfurase BCQ_4183 ENOG4105D1H recombination factor protein RarA BCQ_4184 ENOG4105D1H recombination factor protein RarA BCQ_4185 ENOG4108VCI transcription factor, rsfa family BCQ_4186 ENOG4105CUZ uba thif-type nad fad binding protein BCQ_4193 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BCQ_4195 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCQ_4196 ENOG41076HS cation diffusion facilitator family transporter BCQ_4197 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BCQ_4199 ENOG4105CKP Polysaccharide Biosynthesis Protein BCQ_4200 ENOG4108QG2 Membrane BCQ_4202 ENOG4105VIE preprotein translocase, subunit YajC BCQ_4205 ENOG41061AI Protein of unknown function (DUF2905) BCQ_4208 ENOG4108HUF Transporter BCQ_4210 ENOG4108IPJ Membrane BCQ_4211 ENOG41082BM Transcriptional regulator, arsr family BCQ_4217 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BCQ_4218 ENOG4108IYU L-aspartate oxidase BCQ_4221 ENOG4108RPX mosc domain containing protein BCQ_4222 ENOG4105CQC Prephenate dehydratase BCQ_4226 ENOG4105EWM Histidine kinase BCQ_4231 ENOG4105X36 (ribosomal) protein BCQ_4233 ENOG4105C03 ribonuclease BCQ_4236 ENOG4107QMS site-determining protein BCQ_4239 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BCQ_4240 ENOG4105DFF Rod shape-determining protein mreb BCQ_4244 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BCQ_4247 ENOG41068KH stage VI sporulation protein D BCQ_4249 ENOG4105D52 delta-aminolevulinic acid dehydratase BCQ_4254 ENOG4105K56 Transcriptional regulator BCQ_4258 ENOG4108IUQ atp-dependent protease BCQ_4264 ENOG4108QCI YvbH-like oligomerisation region BCQ_4284 ENOG4105M59 Phosphodiesterase, mj0936 family BCQ_4285 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BCQ_4287 ENOG4108XJQ germination protein BCQ_4289 ENOG4108PCX Major Facilitator BCQ_4291 ENOG4105KBX Transcriptional regulator, TetR family BCQ_4294 ENOG4105PFC Transcriptional regulator BCQ_4298 ENOG4105ESI atpase involved in dna repair BCQ_4303 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BCQ_4312 ENOG4105DZC cytosine deaminase BCQ_4313 ENOG4108JCI Transcriptional regulator BCQ_4315 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BCQ_4316 ENOG4108Z40 Transcriptional regulator BCQ_4317 ENOG4105RHA ABC transporter, permease BCQ_4318 ENOG4108IUX (ABC) transporter BCQ_4319 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BCQ_4320 ENOG4105ER2 Ompa motb domain protein BCQ_4321 ENOG4105E14 MotA TolQ exbB proton channel BCQ_4322 ENOG4108VXD carboxy-peptidase BCQ_4324 ENOG4105E33 succinate dehydrogenase BCQ_4326 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BCQ_4329 ENOG4105K63 Thioredoxin BCQ_4330 ENOG4105C10 Electron transfer flavoprotein BCQ_4331 ENOG4105BZJ Electron transfer flavoprotein BCQ_4332 ENOG41060WC Enoyl-CoA hydratase BCQ_4333 ENOG4107Z3H Transcriptional regulator, TetR family BCQ_4334 ENOG4105CEY Amp-dependent synthetase and ligase BCQ_4343 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCQ_4346 ENOG4105DR4 Methyltransferase BCQ_4349 ENOG4105KFN sortase, SrtB family BCQ_4350 ENOG4105E0A ABC, transporter BCQ_4353 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BCQ_4354 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BCQ_4356 ENOG4105FE9 pseudouridine synthase BCQ_4359 ENOG4105DCG PHP domain protein BCQ_4368 ENOG4108RWN rrna methyltransferase BCQ_4372 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_4373 ENOG4105CW7 secretion protein, HlyD family BCQ_4374 ENOG4108JGH Tetr family transcriptional regulator BCQ_4375 ENOG4105CN9 Peptidase m42 family protein BCQ_4379 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BCQ_4380 ENOG4105C22 threonyL-tRNA synthetase BCQ_4381 ENOG4108TDW sporulation protein YtxC BCQ_4385 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BCQ_4386 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BCQ_4387 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BCQ_4390 ENOG4105C2M dna polymerase I BCQ_4391 ENOG4105BZU Histidine kinase BCQ_4392 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCQ_4397 ENOG4108HMX isocitrate dehydrogenase (NADP) BCQ_4398 ENOG4105BZN citrate synthase BCQ_4400 ENOG4108REF Sporulation integral membrane protein ytvi BCQ_4401 ENOG4105FS0 cytoplasmic membrane protein BCQ_4406 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BCQ_4407 ENOG4105C6K Malic enzyme BCQ_4408 ENOG4105C0B DNA polymerase III (alpha subunit) BCQ_4409 ENOG4105VV2 BCQ_4411 ENOG4105SFS phosphoesterase RecJ domain protein BCQ_4419 ENOG4105DC7 peptidase M24 BCQ_4426 ENOG4105Z7P Acetyltransferase (GNAT) family BCQ_4427 ENOG41082W1 Cupin 2, conserved barrel domain protein BCQ_4429 ENOG4105IYK transposase BCQ_4430 ENOG4105DQ6 Transposase BCQ_4433 ENOG4107YZX Universal stress protein BCQ_4449 ENOG4108JYZ YitT family BCQ_4455 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BCQ_4456 ENOG4105KBJ sporulation protein ytfj BCQ_4459 ENOG4105EFZ amidohydrolase BCQ_4461 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BCQ_4466 ENOG4105C5Q Transcriptional regulator BCQ_4468 ENOG4105U5Y Transcriptional regulator BCQ_4470 ENOG4105C28 cystathionine BCQ_4474 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCQ_4476 ENOG4105EMN RNA polymerase sigma factor BCQ_4479 ENOG4105F1V Acetoin utilization protein BCQ_4480 ENOG4105W87 Cbs domain BCQ_4481 ENOG4105DGU Histone deacetylase BCQ_4482 ENOG4106HB6 Alpha beta hydrolase BCQ_4484 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BCQ_4487 ENOG4105EP9 oxidoreductase BCQ_4492 ENOG4105ETE Transcriptional regulator (LacI family BCQ_4497 ENOG4105C88 aminopeptidase BCQ_4505 ENOG4108VDD TRNA binding domain protein BCQ_4511 ENOG4105C8F Beta-lactamase domain protein BCQ_4514 ENOG4108V15 phosphotransferase enzyme family BCQ_4515 ENOG4108IUM Glycogen debranching enzyme BCQ_4517 ENOG4107QSE Dipeptidase BCQ_4518 ENOG4105YW5 deoR family transcriptional regulator BCQ_4521 ENOG4105CBX hi0933 family BCQ_4522 ENOG4105CBX hi0933 family BCQ_4528 ENOG4108VJ1 Transcriptional regulator (CarD family BCQ_4529 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BCQ_4533 ENOG4108ZAF Molybdopterin BCQ_4534 ENOG4105D7V transposase BCQ_4536 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BCQ_4537 ENOG4105CVM Molybdenum cofactor synthesis domain protein BCQ_4539 ENOG4105D06 uba thif-type nad fad binding protein BCQ_4540 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCQ_4544 ENOG41085GJ domain protein BCQ_4546 ENOG4105DWV Homoserine O-trans-acetylase BCQ_4548 ENOG4108B31 Spore germination protein BCQ_4554 ENOG410605W Major Facilitator BCQ_4555 ENOG4107S91 Sodium hydrogen exchanger BCQ_4556 ENOG4105NCW Trka-c domain protein BCQ_4559 ENOG4105C19 ABC transporter BCQ_4563 ENOG4105N5T Radical SAM Protein BCQ_4565 ENOG4108IUX (ABC) transporter BCQ_4573 ENOG4105E8V Alpha Beta Hydrolase Fold protein BCQ_4574 ENOG4108Z0R Transferase BCQ_4575 ENOG4105YVM Phosphoesterase, PA-phosphatase related BCQ_4576 ENOG4105BZF Glycosyl transferase (Group 1 BCQ_4578 ENOG4108RIR Molybdenum cofactor biosynthesis protein BCQ_4581 ENOG4108MK9 spermidine N(1)-acetyltransferase BCQ_4589 ENOG4105BZU Histidine kinase BCQ_4590 ENOG4105BZU Histidine kinase BCQ_4591 ENOG4107S9D Alpha beta hydrolase BCQ_4592 ENOG4107T7U Sulfatase BCQ_4596 ENOG4105D2X ABC transporter substrate-binding protein BCQ_4598 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BCQ_4608 ENOG4108V2W Carbonate dehydratase BCQ_4609 ENOG4105C4M (Ubiquinol oxidase) subunit I BCQ_4610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BCQ_4620 ENOG41087YS Phage shock protein A BCQ_4625 ENOG4105BZU Histidine kinase BCQ_4626 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_4632 ENOG4108UGV hypoxanthine phosphoribosyltransferase BCQ_4633 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BCQ_4638 ENOG4105C19 ABC transporter BCQ_4641 ENOG4107ZTW SNARE associated Golgi BCQ_4645 ENOG4105DQ6 Transposase BCQ_4646 ENOG4105IYK transposase BCQ_4648 ENOG4105C19 ABC transporter BCQ_4649 ENOG41086D8 Transcriptional regulator BCQ_4651 ENOG41082BM Transcriptional regulator, arsr family BCQ_4659 ENOG4105C6Z Gluconate BCQ_4660 ENOG4105FDP GntR family transcriptional regulator BCQ_4664 ENOG41069H0 dihydroorotase EC 3.5.2.3 BCQ_4668 ENOG4105DTQ mandelate racemase muconate lactonizing BCQ_4671 ENOG4108IPT Naphthoate synthase BCQ_4672 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BCQ_4674 ENOG4105E4F Isochorismate synthase BCQ_4675 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BCQ_4677 ENOG4105VEQ Cold shock protein BCQ_4688 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BCQ_4708 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BCQ_4717 ENOG4105KT7 mgtC SapB transporter BCQ_4718 ENOG4107PBV potassium channel BCQ_4721 ENOG4105WG9 Conserved Protein BCQ_4723 ENOG4105CHM Aminotransferase BCQ_4724 ENOG4108ZB6 transcriptional regulator AsnC family BCQ_4725 ENOG4105C5I Dehydrogenase BCQ_4726 ENOG4108MUZ hydrolase BCQ_4728 ENOG4105C87 Aminotransferase class I and II BCQ_4731 ENOG4105Y38 Kinase-associated protein B BCQ_4733 ENOG4107R3E Citrate transporter BCQ_4736 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BCQ_4737 ENOG4105KA0 thioesterase Superfamily protein BCQ_4740 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCQ_4744 ENOG41069ER domain protein BCQ_4747 ENOG4105CEP NADH dehydrogenase BCQ_4752 ENOG4105EWC Purine nucleoside phosphorylase BCQ_4755 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BCQ_4759 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BCQ_4760 ENOG4105C4B ABC transporter, permease BCQ_4761 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BCQ_4770 ENOG41083MR nifu domain-containing protein BCQ_4773 ENOG4108W5N phosphatidylglycerophosphatase a BCQ_4775 ENOG4105DYS nad(p)h dehydrogenase (quinone) BCQ_4777 ENOG4105D4U had-superfamily hydrolase, subfamily iia BCQ_4780 ENOG4105CBT Fructose-1,6-bisphosphatase BCQ_4783 ENOG4105MMD transcriptional regulator BCQ_4784 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BCQ_4785 ENOG4107TXC Transcriptional regulator BCQ_4786 ENOG41090T1 Membrane BCQ_4791 ENOG4105FAA peptidase M23 BCQ_4793 ENOG4105KZD Domain of unknown function (DUF1805) BCQ_4794 ENOG4107R8B 5'-nucleotidase BCQ_4795 ENOG4105DIW FeS assembly protein SUFB BCQ_4796 ENOG4108UNV SUF system FeS assembly protein, NifU family BCQ_4797 ENOG4105C9B Cysteine desulfurase BCQ_4798 ENOG4105JRK feS assembly protein SufD BCQ_4799 ENOG4105C3K feS assembly ATPase SufC BCQ_4801 ENOG4105D01 (LipO)protein BCQ_4802 ENOG4105D01 (LipO)protein BCQ_4803 ENOG4108UMI ABC transporter, permease BCQ_4809 ENOG41080E8 Transcriptional regulator, Spx MgsR family BCQ_4822 ENOG4108W8B Beta-lactamase domain protein BCQ_4823 ENOG4105C1G acyl-Coa dehydrogenase BCQ_4824 ENOG4105CHU acetyl-coa acetyltransferase BCQ_4828 ENOG4105DZ1 carboxypeptidase BCQ_4832 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCQ_4833 ENOG4105D7V transposase BCQ_4837 ENOG4108SUT Major Facilitator Superfamily BCQ_4838 ENOG4107R7I amino acid BCQ_4841 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCQ_4843 ENOG4107AYK membrAne BCQ_4850 ENOG4107ZTW SNARE associated Golgi BCQ_4852 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BCQ_4853 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_4854 ENOG4105BZU Histidine kinase BCQ_4858 ENOG4105C8Q Methyl-accepting chemotaxis BCQ_4859 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BCQ_4860 ENOG4105VG1 fes assembly suf system protein BCQ_4861 ENOG4105D4Y metalloprotease BCQ_4865 ENOG4107S91 Sodium hydrogen exchanger BCQ_4866 ENOG4105NCW Trka-c domain protein BCQ_4868 ENOG4108RMU ferritin dps family protein BCQ_4871 ENOG4108URH decarboxylase BCQ_4875 ENOG4105D9N nucleoside BCQ_4876 ENOG4105D9N nucleoside BCQ_4879 ENOG4108RYK Nad-dependent epimerase dehydratase BCQ_4882 ENOG4105CV8 reductase BCQ_4883 ENOG4105F27 Major Facilitator BCQ_4884 ENOG4105KVH Transcriptional regulator BCQ_4887 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BCQ_4888 ENOG4105D4A Cell wall formation (By similarity) BCQ_4892 ENOG4105C8Q Methyl-accepting chemotaxis BCQ_4899 ENOG4105C5H ABC transporter BCQ_4900 ENOG4108MK9 spermidine N(1)-acetyltransferase BCQ_4901 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BCQ_4903 ENOG4108IPW abc transporter atp-binding protein BCQ_4904 ENOG4105CM4 permease protein BCQ_4910 ENOG4105C19 ABC transporter BCQ_4914 ENOG4107ZTW SNARE associated Golgi BCQ_4918 ENOG4105C19 ABC transporter BCQ_4923 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BCQ_4924 ENOG41086D8 Transcriptional regulator BCQ_4927 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BCQ_4928 ENOG4105C0R drug resistance transporter emrb qaca subfamily BCQ_4930 ENOG4108ZHR arsR family transcriptional regulator BCQ_4931 ENOG4105DHF Membrane BCQ_4934 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BCQ_4936 ENOG4105XZU Preprotein translocase, subunit SecG BCQ_4937 ENOG41067MG lrgb family BCQ_4947 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_4948 ENOG4105RHA ABC transporter, permease BCQ_4949 ENOG4108IUX (ABC) transporter BCQ_4954 ENOG4105BZU Histidine kinase BCQ_4955 ENOG4105WH1 Two component transcriptional regulator luxr family BCQ_4967 ENOG41090VF Stage v sporulation protein ac BCQ_4968 ENOG4105CZ3 stage V sporulation protein ad BCQ_4971 ENOG4108QY0 Membrane BCQ_4972 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BCQ_4973 ENOG4105KRI phosphocarrier protein (HPr BCQ_4975 ENOG4105CHW UPF0052 protein BCQ_4977 ENOG4108Z4K mutator MutT protein BCQ_4979 ENOG4105C3M thioredoxin reductase BCQ_4981 ENOG4108S4C acetyltransferase BCQ_4985 ENOG41086DT Membrane protein of unknown function BCQ_4988 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BCQ_4991 ENOG4107TXC Transcriptional regulator BCQ_4998 ENOG4105DUM transcriptional regulator, lysR family BCQ_5000 ENOG4108WS4 fmn reductase BCQ_5001 ENOG4105C5H ABC transporter BCQ_5003 ENOG4105BZ1 (ABC) transporter BCQ_5005 ENOG4105CN1 protease BCQ_5006 ENOG4105CRP Part of the ABC transporter FtsEX involved in BCQ_5007 ENOG4105CAK Cell division ATP-binding protein ftsE BCQ_5009 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BCQ_5011 ENOG4105MS2 ribosomal subunit Interface protein BCQ_5012 ENOG4105VEQ Cold shock protein BCQ_5013 ENOG41081UC Inherit from COG: Competence protein BCQ_5015 ENOG4105K4H Nlp p60 protein BCQ_5016 ENOG4105KVH Transcriptional regulator BCQ_5019 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BCQ_5020 ENOG4108KGH TRANSCRIPTIONal BCQ_5021 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BCQ_5022 ENOG4105C6Y Udp-glucose 6-dehydrogenase BCQ_5024 ENOG4105ESV Glycosyl transferase, family 4 BCQ_5027 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BCQ_5031 ENOG4105F8D glycoside hydrolase family 4 BCQ_5032 ENOG4105VCP PTS System BCQ_5033 ENOG4105CK1 PTS System BCQ_5035 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BCQ_5039 ENOG4105VCP PTS System BCQ_5041 ENOG4105VZJ PTS System BCQ_5044 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BCQ_5048 ENOG4105ECB domain protein BCQ_5049 ENOG4107RSM transcriptional regulator BCQ_5056 ENOG4105DAA L-lactate BCQ_5058 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BCQ_5060 ENOG4105E0M Sulfatase BCQ_5067 ENOG4107R8N Glycosyl transferase, family 2 BCQ_5068 ENOG4105C94 Transporter BCQ_5069 ENOG41069ER domain protein BCQ_5074 ENOG4105KBK Zinc finger, swim domain protein BCQ_5075 ENOG4105C0D helicase BCQ_5081 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BCQ_5083 ENOG4107RBB ABC transporter, permease BCQ_5084 ENOG4105C19 ABC transporter BCQ_5086 ENOG4105CXY transporter BCQ_5089 ENOG4105BZU Histidine kinase BCQ_5090 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_5091 ENOG4105DG6 mannose-6-phosphate isomerase BCQ_5092 ENOG4105DM4 PTS System BCQ_5095 ENOG4105CMR udp-glucose 4-epimerase BCQ_5096 ENOG4105CMR udp-glucose 4-epimerase BCQ_5098 ENOG4106MCE EamA-like transporter family BCQ_5099 ENOG4108KN0 Choline kinase BCQ_5102 ENOG4105KPE licD family BCQ_5104 ENOG4108KGH TRANSCRIPTIONal BCQ_5105 ENOG4105DG6 mannose-6-phosphate isomerase BCQ_5106 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BCQ_5108 ENOG4108TJN glycosyl transferase group 1 BCQ_5110 ENOG4105K64 Glycosyl transferase, family 2 BCQ_5112 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BCQ_5113 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BCQ_5114 ENOG4107YJ4 chain length determinant protein BCQ_5115 ENOG4105HTX biosynthesis protein BCQ_5116 ENOG4108QV3 biosynthesis protein BCQ_5120 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BCQ_5122 ENOG4105FRN stage II sporulation protein BCQ_5125 ENOG4105DY9 regulatoR BCQ_5129 ENOG4106778 Protein of unknown function (DUF1146) BCQ_5130 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCQ_5131 ENOG4105C8S subunit m BCQ_5132 ENOG4105D65 subunit l BCQ_5137 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BCQ_5138 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCQ_5140 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BCQ_5141 ENOG4105BZU Histidine kinase BCQ_5151 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BCQ_5152 ENOG41062M3 atp synthase BCQ_5158 ENOG4108YZG isomerase BCQ_5161 ENOG4108VGI doxx family BCQ_5162 ENOG4107XC4 flavin reductase domain protein, FMN-binding BCQ_5166 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BCQ_5168 ENOG4108ZXQ stage ii sporulation protein r BCQ_5169 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BCQ_5170 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BCQ_5172 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BCQ_5173 ENOG4105CBT Fructose-1,6-bisphosphatase BCQ_5175 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BCQ_5182 ENOG4105C1G acyl-Coa dehydrogenase BCQ_5183 ENOG4105C1G acyl-Coa dehydrogenase BCQ_5184 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BCQ_5186 ENOG4105DF6 Fe-S oxidoreductase BCQ_5189 ENOG4105BZU Histidine kinase BCQ_5194 ENOG4105BZU Histidine kinase BCQ_5195 ENOG4105KCT ABC transporter BCQ_5196 ENOG4108M15 ABC transporter BCQ_5197 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BCQ_5199 ENOG4105IIU Aminopeptidase BCQ_5203 ENOG4105EMN RNA polymerase sigma factor BCQ_5205 ENOG410684U Domain of unknown function (DUF1934) BCQ_5209 ENOG4105CYW agmatinase BCQ_5211 ENOG4105DXB Major Facilitator superfamily BCQ_5212 ENOG4107SWG transcriptional regulator MERR family BCQ_5213 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BCQ_5214 ENOG4105BZ4 penicillin-binding protein BCQ_5215 ENOG4108XFG YwhD family BCQ_5216 ENOG4108Z4T Peptidase M50 BCQ_5217 ENOG41069HH 4-oxalocrotonate tautomerase BCQ_5219 ENOG4105DCI Phosphohydrolase BCQ_5220 ENOG4108MES Periplasmic binding protein BCQ_5221 ENOG4105E0A ABC, transporter BCQ_5222 ENOG4105EHG Permease protein BCQ_5223 ENOG4105DQ5 transport system permease protein BCQ_5225 ENOG4108VCI transcription factor, rsfa family BCQ_5228 ENOG4108IJ2 phosphate acetyltransferase BCQ_5231 ENOG4108VKI Cell wall hydrolase BCQ_5235 ENOG4107SVH Potassium channel protein BCQ_5238 ENOG410667J hydrolase BCQ_5239 ENOG4105VCH membrane BCQ_5241 ENOG4108TU7 Inherit from COG: (ABC) transporter BCQ_5242 ENOG4105CJ1 ABC, transporter BCQ_5243 ENOG41090WU lipolytic protein G-D-S-L family BCQ_5246 ENOG4105D6E homoserine dehydrogenase BCQ_5250 ENOG4108Y4K DNA-binding transcriptional activator BCQ_5252 ENOG4105WH1 Two component transcriptional regulator luxr family BCQ_5253 ENOG4105BZU Histidine kinase BCQ_5254 ENOG4105DWF phosphomethylpyrimidine kinase BCQ_5255 ENOG4105BZU Histidine kinase BCQ_5256 ENOG4105VCD cytoplasmic protein BCQ_5257 ENOG4105D22 carbon starvation protein BCQ_5258 ENOG4105DY9 regulatoR BCQ_5259 ENOG41079KZ Major Facilitator Superfamily BCQ_5261 ENOG4105CG5 Glycosyl transferase (Group 1 BCQ_5263 ENOG4105EN6 Membrane BCQ_5264 ENOG4106YBV Methyl-accepting chemotaxis BCQ_5266 ENOG4108S4H thioesterase Superfamily protein BCQ_5267 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BCQ_5270 ENOG4105K64 Glycosyl transferase, family 2 BCQ_5273 ENOG4105C5H ABC transporter BCQ_5277 ENOG41067SE Tetr family transcriptional regulator BCQ_5279 ENOG4105E0X reductase BCQ_5280 ENOG4106F5Q Membrane BCQ_5283 ENOG4105DY9 regulatoR BCQ_5284 ENOG4108HRK Histidine kinase BCQ_5285 ENOG4107RGD Major Facilitator superfamily BCQ_5286 ENOG4107RGD Major Facilitator superfamily BCQ_5289 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BCQ_5291 ENOG4105IW1 AmiS UreI transporter BCQ_5298 ENOG4105CMR udp-glucose 4-epimerase BCQ_5299 ENOG4108UT2 hemolysin iii BCQ_5301 ENOG4105C1J atp-dependent rna helicase BCQ_5303 ENOG4105DPN Oligoendopeptidase f BCQ_5307 ENOG4105C0H protease BCQ_5308 ENOG4105Q2H domain protein BCQ_5311 ENOG4105BZU Histidine kinase BCQ_5312 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BCQ_5318 ENOG4105CDU Replicative dna helicase BCQ_5320 ENOG4105BZR domain protein BCQ_5321 ENOG4108XMW Membrane BCQ_5323 ENOG4108UUM single-stranded DNA-binding protein BCQ_5325 ENOG4105C3G gtp-binding protein BCQ_5326 ENOG4105VDK protein, conserved in bacteria BCQ_5327 ENOG4105D8X mechanosensitive ion channel BCQ_5328 ENOG4108ZDA Sporulation protein YyaC BCQ_5329 ENOG4105FA0 parb-like partition protein BCQ_5330 ENOG4107QJE Chromosome Partitioning Protein BCQ_5336 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BCQ_PI011 ENOG4105EKQ RNA-directed DNA polymerase BCQ_PI031 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BCQ_PI032 ENOG4105KNA -acetyltransferase BCQ_PI033 ENOG41087PP glycosyltransferase MGT family BCQ_PI034 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BCQ_PI051 ENOG4105H67 Protein of unknown function (DUF421) BCQ_PI052 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BCQ_PI059 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCQ_PI064 ENOG4108IBT Inherit from COG: transposase BCQ_PI068 ENOG4108B31 Spore germination protein BCQ_PI074 ENOG4108NHD germination protein BCQ_PI078 ENOG4108W2Y isochorismatase BCQ_PI082 ENOG4108A04 Beta-lactamase BCQ_PI086 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BCQ_PI100 ENOG4105BZ1 (ABC) transporter BCQ_PI101 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BCQ_PI104 ENOG4105CZV ABC transporter BCQ_PI119 ENOG4105EKQ RNA-directed DNA polymerase BCQ_PI121 ENOG4105EKQ RNA-directed DNA polymerase BCQ_PI125 ENOG4105EKQ RNA-directed DNA polymerase BCQ_PI135 ENOG4108M1A Chitin-binding protein BCQ_PI138 ENOG4107SDU Methyl-accepting chemotaxis BCQ_PI142 ENOG4105K4H Nlp p60 protein BCQ_PI161 ENOG4105DQ6 Transposase BCQ_PI164 ENOG4105E1K spore germination protein BCQ_PI165 ENOG4108B31 Spore germination protein BCQ_PI167 ENOG4108QY0 Membrane BCQ_PI170 ENOG4105CZ3 stage V sporulation protein ad BCQ_PI171 ENOG41090VF Stage v sporulation protein ac BCQ_PI174 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BCQ_PI177 ENOG4105D9M gamma-glutamylcysteine synthetase BCQ_PI179 ENOG4105C4W S-formylglutathione hydrolase BCQ_PI180 ENOG4105KVH Transcriptional regulator BCQ_PI184 ENOG4105K70 DNA-binding protein BCQ_PI186 ENOG4105KRN Transcriptional regulator, abrb family BCQ_PI197 ENOG4108Z7R Chaperone CsaA BCQ_PI200 ENOG4105DHF Membrane BCQ_PI202 ENOG4105DQ6 Transposase BCQ_PI206 ENOG4105D7V transposase BCQ_PI212 ENOG4105D7V transposase BCQ_PI219 ENOG4105EKQ RNA-directed DNA polymerase BCQ_PI220 ENOG4107QZI cell division protein FtsK BCQ_PI228 ENOG4105VIZ double-strand break repair protein BCQ_PT05 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BCQ_PT15 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BCQ_PT39 ENOG4105IG6 Phage terminase, large subunit BCQ_PT41 ENOG4108C33 Resolvase BCQ_PT47 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)