locus-tag	class	description
BF33_10	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF33_100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF33_1000	COG1011	Hydrolase
BF33_1005	COG1131	(ABC) transporter
BF33_1007	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_1011	COG0778	Nitroreductase
BF33_1012	COG1733	regulation of RNA biosynthetic process
BF33_1016	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF33_1017	COG3344	reverse transcriptase
BF33_1018	COG1051	belongs to the nudix hydrolase family
BF33_1019	COG0537	adenosine 5'-monophosphoramidase activity
BF33_1020	COG3344	reverse transcriptase
BF33_1023	COG1309	transcriptional regulator
BF33_1024	COG2814	Major facilitator Superfamily
BF33_1027	COG1288	antiporter activity
BF33_1028	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF33_1031	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF33_1038	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF33_1040	COG2031	fatty acid transporter
BF33_1042	COG1309	transcriptional regulator
BF33_1043	COG2076	Multidrug Resistance protein
BF33_1046	COG2814	Major facilitator Superfamily
BF33_1047	COG1846	Transcriptional regulator
BF33_1049	COG0477	Major facilitator Superfamily
BF33_1057	COG3409	Peptidoglycan-binding domain 1 protein
BF33_1057	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF33_1061	COG2207	Transcriptional regulator
BF33_1061	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_1062	COG0662	Cupin 2, conserved barrel domain protein
BF33_1065	COG1595	DNA-templated transcription, initiation
BF33_1069	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF33_1072	COG0531	amino acid
BF33_1073	COG1522	sequence-specific DNA binding
BF33_1074	COG1335	isochorismatase
BF33_1076	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF33_1077	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF33_1078	COG1760	l-serine dehydratase
BF33_1079	COG1760	l-serine dehydratase
BF33_1080	COG0814	amino acid
BF33_1082	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_1086	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF33_1090	COG0457	Tetratricopeptide repeat
BF33_1091	COG1609	Transcriptional regulator
BF33_1092	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF33_1093	COG0561	phosphatase activity
BF33_1094	COG0673	inositol 2-dehydrogenase activity
BF33_1095	COG0738	Major facilitator superfamily
BF33_1099	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF33_11	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF33_1101	COG0583	DNA-binding transcription factor activity
BF33_1103	COG1139	Iron-sulfur cluster binding protein
BF33_1104	COG1556	Lactate utilization protein
BF33_1105	COG2271	Major facilitator Superfamily
BF33_1106	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_1108	COG3850	Histidine kinase
BF33_1108	COG5002	protein histidine kinase activity
BF33_1111	COG0577	efflux transmembrane transporter activity
BF33_1112	COG1136	(ABC) transporter
BF33_1115	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF33_1119	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_1121	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF33_1122	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_1127	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF33_1132	COG3850	Histidine kinase
BF33_1132	COG5002	protein histidine kinase activity
BF33_1133	COG0745	RESPONSE REGULATOR receiver
BF33_1138	COG2814	Major facilitator Superfamily
BF33_1147	COG2169	Transcriptional regulator
BF33_1151	COG0346	lactoylglutathione lyase activity
BF33_1154	COG1522	sequence-specific DNA binding
BF33_1157	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF33_1157	COG3320	Male sterility
BF33_1158	COG0456	acetyltransferase
BF33_1159	COG0745	RESPONSE REGULATOR receiver
BF33_1160	COG5002	protein histidine kinase activity
BF33_1164	COG0640	Transcriptional regulator
BF33_1165	COG0798	PFAM Bile acid sodium symporter
BF33_1170	COG1136	(ABC) transporter
BF33_1171	COG4641	Protein conserved in bacteria
BF33_1172	COG2267	carboxylic ester hydrolase activity
BF33_1173	COG1575	Belongs to the MenA family. Type 1 subfamily
BF33_1175	COG5609	conserved protein (DUF2294)
BF33_1176	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF33_1178	COG0288	reversible hydration of carbon dioxide
BF33_1179	COG0415	Belongs to the DNA photolyase family
BF33_1186	COG0598	Magnesium transport protein CorA
BF33_1187	COG1846	Transcriptional regulator
BF33_1188	COG0583	DNA-binding transcription factor activity
BF33_1192	COG1335	isochorismatase
BF33_1193	COG2267	carboxylic ester hydrolase activity
BF33_1194	COG0753	catalase activity
BF33_1195	COG0737	Belongs to the 5'-nucleotidase family
BF33_1197	COG1115	amino acid carrier protein
BF33_1198	COG2066	Belongs to the glutaminase family
BF33_1199	COG4191	Histidine kinase
BF33_1200	COG0784	Response regulator, receiver
BF33_1201	COG0697	spore germination
BF33_1202	COG0531	amino acid
BF33_1206	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF33_1207	COG1114	Component of the transport system for branched-chain amino acids
BF33_1208	COG0531	amino acid
BF33_1209	COG0322	excinuclease ABC activity
BF33_1211	COG1396	sequence-specific DNA binding
BF33_1212	COG0252	asparaginase activity
BF33_1213	COG1027	Aspartate ammonia-lyase
BF33_1215	COG1063	alcohol dehydrogenase
BF33_1221	COG1113	amino acid transport
BF33_1222	COG1280	lysine exporter protein (LysE YggA)
BF33_1223	COG3403	YqcI/YcgG family
BF33_1225	COG5577	PFAM Coat F domain
BF33_1228	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_1230	COG3848	Pyruvate phosphate dikinase
BF33_1230	COG0574	Belongs to the PEP-utilizing enzyme family
BF33_1233	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF33_124	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF33_1240	COG1960	acyl-CoA dehydrogenase activity
BF33_1242	COG0640	Transcriptional regulator
BF33_1243	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_1246	COG1414	Transcriptional regulator
BF33_1247	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF33_1248	COG1984	allophanate hydrolase subunit 2
BF33_125	COG1459	type II secretion system
BF33_1254	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF33_1262	COG4335	DNA alkylation repair
BF33_1264	COG0833	amino acid
BF33_1266	COG0730	response to heat
BF33_127	COG4970	Tfp pilus assembly protein FimT
BF33_1275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_1279	COG0456	acetyltransferase
BF33_1280	COG2207	Transcriptional regulator
BF33_1285	COG1136	(ABC) transporter
BF33_1287	COG1725	Transcriptional regulator
BF33_1293	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF33_1294	COG2814	Major facilitator Superfamily
BF33_1295	COG2508	Transcriptional regulator
BF33_1297	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF33_13	COG1534	Rna-binding protein
BF33_1300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF33_1301	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF33_1302	COG2723	6-phospho-beta-galactosidase activity
BF33_1303	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF33_1304	COG1024	Enoyl-CoA hydratase
BF33_1305	COG0183	Belongs to the thiolase family
BF33_1306	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_1308	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF33_1310	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF33_1314	COG1846	Transcriptional regulator
BF33_1315	COG0778	Nitroreductase
BF33_1321	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF33_1323	COG0753	catalase activity
BF33_1324	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF33_1326	COG0463	Glycosyl transferase, family 2
BF33_1330	COG0463	Glycosyl transferase, family 2
BF33_1335	COG0714	Associated with various cellular activities
BF33_1340	COG0346	lactoylglutathione lyase activity
BF33_1341	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_1343	COG3279	Response regulator of the LytR AlgR family
BF33_1345	COG4377	Putative membrane peptidase family (DUF2324)
BF33_1348	COG3655	Transcriptional regulator
BF33_1350	COG1785	Belongs to the alkaline phosphatase family
BF33_1351	COG3239	Fatty acid desaturase
BF33_1352	COG1690	Belongs to the RtcB family
BF33_1353	COG0833	amino acid
BF33_1354	COG1414	Transcriptional regulator
BF33_1355	COG4187	Peptidase family M20/M25/M40
BF33_1360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF33_1361	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF33_1363	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_1367	COG2329	Antibiotic biosynthesis monooxygenase
BF33_1374	COG1070	Carbohydrate kinase
BF33_1375	COG2390	Transcriptional regulator
BF33_1377	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF33_1379	COG1879	ABC-type sugar transport system periplasmic component
BF33_138	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF33_1383	COG3290	protein histidine kinase activity
BF33_1383	COG3829	transcription factor binding
BF33_1385	COG1024	Enoyl-CoA hydratase
BF33_1386	COG2610	gluconate transmembrane transporter activity
BF33_1388	COG3584	3D domain protein
BF33_1388	COG1388	LysM domain
BF33_1395	COG1605	Chorismate mutase
BF33_1395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF33_1397	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF33_1398	COG0287	Prephenate dehydrogenase
BF33_1401	COG1309	transcriptional regulator
BF33_1402	COG1033	growth of symbiont in host cell
BF33_1402	COG2409	Drug exporters of the RND superfamily
BF33_1404	COG0488	(ABC) transporter
BF33_1405	COG1368	sulfuric ester hydrolase activity
BF33_1406	COG0861	Integral membrane protein TerC family
BF33_1408	COG0726	polysaccharide deacetylase
BF33_1410	COG4912	Dna alkylation repair
BF33_1414	COG2318	DinB family
BF33_1415	COG0697	spore germination
BF33_1420	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF33_1429	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF33_1430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF33_1431	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF33_1433	COG0628	permease
BF33_144	COG1725	Transcriptional regulator
BF33_1442	COG1131	(ABC) transporter
BF33_1445	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF33_1447	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF33_1448	COG0436	Aminotransferase
BF33_145	COG1131	(ABC) transporter
BF33_1455	COG2226	methyltransferase
BF33_1458	COG2261	transglycosylase associated protein
BF33_1462	COG2814	Major facilitator Superfamily
BF33_1462	COG0477	Major facilitator Superfamily
BF33_1463	COG4533	DNA binding
BF33_1464	COG0789	Transcriptional regulator
BF33_1465	COG1664	Polymer-forming cytoskeletal
BF33_1467	COG2814	Major facilitator Superfamily
BF33_1471	COG1307	EDD domain protein, DegV family
BF33_1473	COG1164	Oligoendopeptidase f
BF33_1480	COG0745	RESPONSE REGULATOR receiver
BF33_1481	COG5002	protein histidine kinase activity
BF33_1482	COG2936	dipeptidyl-peptidase activity
BF33_1489	COG4948	Mandelate Racemase Muconate Lactonizing
BF33_1491	COG4166	transmembrane transport
BF33_1492	COG0519	Catalyzes the synthesis of GMP from XMP
BF33_1493	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF33_1496	COG0586	Pfam SNARE associated Golgi protein
BF33_15	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF33_1504	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF33_1505	COG3938	Belongs to the proline racemase family
BF33_1507	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF33_1508	COG1012	belongs to the aldehyde dehydrogenase family
BF33_1509	COG1115	amino acid carrier protein
BF33_1510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF33_1512	COG3397	chitin binding
BF33_1517	COG4637	Psort location Cytoplasmic, score
BF33_152	COG2076	Multidrug Resistance protein
BF33_1521	COG0514	ATP-dependent DNA helicase (RecQ)
BF33_1522	COG2105	PFAM AIG2 family protein
BF33_1525	COG3973	AAA domain
BF33_153	COG2076	Multidrug Resistance protein
BF33_1536	COG0658	competence protein
BF33_1536	COG2333	competence protein COMEC
BF33_1540	COG2226	methyltransferase
BF33_1541	COG2205	protein histidine kinase activity
BF33_1544	COG1819	glycosyl
BF33_1545	COG3397	chitin binding
BF33_1546	COG2153	protein acetylation
BF33_1547	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF33_155	COG1609	Transcriptional regulator
BF33_1550	COG0740	serine-type endopeptidase activity
BF33_1552	COG4175	Glycine betaine
BF33_1552	COG0517	IMP dehydrogenase activity
BF33_1553	COG4176	ABC-type proline glycine betaine transport system permease component
BF33_156	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_1561	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF33_1561	COG0456	acetyltransferase
BF33_1562	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_1564	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF33_1565	COG0022	dehydrogenase e1 component
BF33_1566	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF33_1567	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF33_157	COG0095	Lipoate-protein ligase
BF33_1571	COG1349	DNA-binding transcription factor activity
BF33_1575	COG3284	Transcriptional regulator
BF33_1579	COG1309	transcriptional regulator
BF33_1585	COG3409	Peptidoglycan-binding domain 1 protein
BF33_1585	COG3773	Cell wall hydrolase
BF33_1586	COG2959	enzyme of heme biosynthesis
BF33_1589	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_1596	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_1597	COG0697	spore germination
BF33_1599	COG0201	protein transport
BF33_16	COG0799	negative regulation of ribosome biogenesis
BF33_1603	COG3227	Zinc metalloprotease (Elastase)
BF33_1604	COG1523	belongs to the glycosyl hydrolase 13 family
BF33_1607	COG0076	glutamate decarboxylase activity
BF33_1609	COG1073	alpha beta
BF33_1617	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF33_162	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF33_1625	COG0322	excinuclease ABC activity
BF33_1628	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF33_163	COG3872	metal-dependent enzyme
BF33_1633	COG4667	esterase of the alpha-beta hydrolase superfamily
BF33_1637	COG3878	Protein conserved in bacteria
BF33_1645	COG1051	belongs to the nudix hydrolase family
BF33_1646	COG0592	DNA-directed DNA polymerase activity
BF33_1650	COG2223	nitrite transmembrane transporter activity
BF33_1658	COG0697	spore germination
BF33_1659	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_166	COG0006	proline dipeptidase activity
BF33_1662	COG0584	glycerophosphoryl diester phosphodiesterase
BF33_1666	COG2814	Major facilitator Superfamily
BF33_1671	COG0693	protein deglycase activity
BF33_1677	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF33_1680	COG0671	phosphoesterase, PA-phosphatase related
BF33_1681	COG0604	alcohol dehydrogenase
BF33_1684	COG2205	protein histidine kinase activity
BF33_1689	COG1794	racemase activity, acting on amino acids and derivatives
BF33_1690	COG1819	glycosyl
BF33_1692	COG5002	protein histidine kinase activity
BF33_1693	COG0561	phosphatase activity
BF33_17	COG2226	methyltransferase
BF33_1700	COG2124	cytochrome p450
BF33_1709	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF33_171	COG3854	ATPases associated with a variety of cellular activities
BF33_1731	COG0582	viral genome integration into host DNA
BF33_1741	COG0662	Cupin 2, conserved barrel domain protein
BF33_1751	COG1484	DNA-dependent DNA replication
BF33_1761	COG0582	viral genome integration into host DNA
BF33_1769	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF33_1771	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_1772	COG0460	homoserine dehydrogenase
BF33_1776	COG0577	efflux transmembrane transporter activity
BF33_1777	COG1136	(ABC) transporter
BF33_1782	COG2205	protein histidine kinase activity
BF33_1783	COG0745	RESPONSE REGULATOR receiver
BF33_1785	COG3773	Cell wall hydrolase
BF33_1786	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BF33_1788	COG3386	PFAM SMP-30 Gluconolaconase
BF33_1792	COG1063	alcohol dehydrogenase
BF33_1795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_1799	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF33_18	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF33_180	COG0511	ligase activity, forming carbon-carbon bonds
BF33_1803	COG2814	Major facilitator Superfamily
BF33_1805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF33_181	COG0439	Biotin carboxylase
BF33_1811	COG3227	Zinc metalloprotease (Elastase)
BF33_1815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF33_182	COG1302	Protein conserved in bacteria
BF33_1820	COG1686	Belongs to the peptidase S11 family
BF33_1821	COG2318	DinB family
BF33_1823	COG0572	uridine kinase
BF33_1824	COG1247	-acetyltransferase
BF33_1826	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF33_1827	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF33_1828	COG1024	Enoyl-CoA hydratase
BF33_1829	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF33_1830	COG0511	ligase activity, forming carbon-carbon bonds
BF33_1831	COG0439	Biotin carboxylase
BF33_1832	COG1960	acyl-CoA dehydrogenase activity
BF33_1835	COG1309	transcriptional regulator
BF33_1837	COG1131	(ABC) transporter
BF33_1840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_1845	COG1309	transcriptional regulator
BF33_1849	COG1876	peptidase activity
BF33_1852	COG1476	TRANSCRIPTIONal
BF33_1853	COG0457	Tetratricopeptide repeat
BF33_1855	COG0737	Belongs to the 5'-nucleotidase family
BF33_1858	COG3718	enzyme involved in inositol metabolism
BF33_1864	COG0673	inositol 2-dehydrogenase activity
BF33_1865	COG2814	Major facilitator Superfamily
BF33_1866	COG1609	Transcriptional regulator
BF33_1867	COG0671	phosphoesterase, PA-phosphatase related
BF33_1868	COG2367	Beta-lactamase
BF33_187	COG0142	geranyltranstransferase activity
BF33_1872	COG1595	DNA-templated transcription, initiation
BF33_1875	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF33_1882	COG1846	Transcriptional regulator
BF33_1883	COG3961	Belongs to the TPP enzyme family
BF33_1884	COG2226	methyltransferase
BF33_1886	COG3615	Tellurite resistance protein tehB
BF33_1886	COG0500	methyltransferase
BF33_1887	COG0577	efflux transmembrane transporter activity
BF33_1887	COG1136	(ABC) transporter
BF33_189	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF33_1890	COG1309	transcriptional regulator
BF33_1896	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_19	COG1555	photosystem II stabilization
BF33_19	COG1596	polysaccharide export
BF33_1901	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF33_1903	COG2971	BadF BadG BcrA BcrD
BF33_1908	COG1649	PFAM Uncharacterised BCR, COG1649
BF33_191	COG0497	DNA recombination
BF33_1913	COG1595	DNA-templated transcription, initiation
BF33_1916	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF33_192	COG0750	zinc metalloprotease
BF33_1923	COG1396	sequence-specific DNA binding
BF33_1927	COG1132	(ABC) transporter
BF33_1928	COG1132	(ABC) transporter
BF33_193	COG0745	RESPONSE REGULATOR receiver
BF33_1931	COG2258	MOSC domain
BF33_1932	COG0583	DNA-binding transcription factor activity
BF33_1935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF33_1936	COG0583	DNA-binding transcription factor activity
BF33_1943	COG0561	phosphatase activity
BF33_1944	COG0010	Belongs to the arginase family
BF33_1947	COG1278	Cold shock
BF33_1949	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_195	COG3093	addiction module antidote protein HigA
BF33_1957	COG1247	-acetyltransferase
BF33_196	COG0584	glycerophosphoryl diester phosphodiesterase
BF33_1964	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_1971	COG2226	methyltransferase
BF33_1975	COG0596	Alpha beta hydrolase
BF33_1977	COG1136	(ABC) transporter
BF33_1978	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF33_1979	COG1187	pseudouridine synthase activity
BF33_198	COG3829	transcription factor binding
BF33_198	COG3290	protein histidine kinase activity
BF33_1980	COG2329	Antibiotic biosynthesis monooxygenase
BF33_1983	COG1115	amino acid carrier protein
BF33_1985	COG2318	DinB family
BF33_1987	COG0776	regulation of translation
BF33_199	COG0280	phosphate acetyltransferase
BF33_1990	COG2814	Major facilitator Superfamily
BF33_1991	COG3251	PFAM MbtH domain protein
BF33_1992	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF33_1993	COG3433	isochorismatase activity
BF33_1993	COG1535	isochorismatase
BF33_1994	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF33_1995	COG1169	isochorismate synthase
BF33_1996	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_1997	COG2223	nitrite transmembrane transporter activity
BF33_2	COG2357	RelA SpoT domain protein
BF33_20	COG2131	deaminase
BF33_200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF33_2001	COG0419	ATPase involved in DNA repair
BF33_2002	COG0420	3'-5' exonuclease activity
BF33_2005	COG1024	Enoyl-CoA hydratase
BF33_2006	COG1280	lysine exporter protein (LysE YggA)
BF33_2007	COG1012	belongs to the aldehyde dehydrogenase family
BF33_2008	COG2084	Dehydrogenase
BF33_2009	COG1960	acyl-CoA dehydrogenase activity
BF33_2010	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF33_2011	COG2079	MmgE PrpD family protein
BF33_2012	COG0372	Belongs to the citrate synthase family
BF33_2013	COG4841	protein insertion into membrane
BF33_2015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF33_2015	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF33_202	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF33_2023	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF33_203	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF33_2039	COG1715	Restriction endonuclease
BF33_2039	COG1787	Restriction endonuclease
BF33_204	COG0022	dehydrogenase e1 component
BF33_2045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_2046	COG0671	phosphoesterase, PA-phosphatase related
BF33_2047	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF33_2048	COG4326	sporulation control protein
BF33_205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF33_2056	COG1509	lysine 2,3-aminomutase activity
BF33_2057	COG3829	transcription factor binding
BF33_2058	COG0456	acetyltransferase
BF33_2059	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF33_206	COG0772	Belongs to the SEDS family
BF33_2060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF33_2061	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF33_2062	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF33_2065	COG5506	Protein of unknown function (DUF1694)
BF33_2066	COG1012	belongs to the aldehyde dehydrogenase family
BF33_2067	COG1253	flavin adenine dinucleotide binding
BF33_207	COG2816	NAD+ diphosphatase activity
BF33_2074	COG1174	glycine betaine transport
BF33_2075	COG1125	glycine betaine transport
BF33_2075	COG0517	IMP dehydrogenase activity
BF33_2082	COG1070	Carbohydrate kinase
BF33_2087	COG1064	alcohol dehydrogenase
BF33_2088	COG1737	Transcriptional regulator
BF33_2090	COG2197	response regulator
BF33_2091	COG2203	Gaf domain
BF33_2091	COG4585	Histidine kinase
BF33_2092	COG0668	transmembrane transport
BF33_2093	COG0071	Belongs to the small heat shock protein (HSP20) family
BF33_2094	COG1051	belongs to the nudix hydrolase family
BF33_2095	COG1335	isochorismatase
BF33_2099	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF33_21	COG2333	competence protein COMEC
BF33_21	COG0658	competence protein
BF33_210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF33_2100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_2104	COG0367	asparagine synthase
BF33_2105	COG0071	Belongs to the small heat shock protein (HSP20) family
BF33_2106	COG1999	signal sequence binding
BF33_2107	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF33_2108	COG1307	EDD domain protein, DegV family
BF33_211	COG0765	amino acid transport
BF33_2110	COG0805	protein transport
BF33_2112	COG1272	protein, Hemolysin III
BF33_2113	COG0204	Acyl-transferase
BF33_2115	COG0768	penicillin binding
BF33_2118	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF33_212	COG1126	abc transporter atp-binding protein
BF33_2121	COG0546	phosphoglycolate phosphatase activity
BF33_2123	COG4473	ABC transporter
BF33_2124	COG1131	(ABC) transporter
BF33_2126	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF33_2127	COG0456	acetyltransferase
BF33_2129	COG1794	racemase activity, acting on amino acids and derivatives
BF33_213	COG4129	membrane
BF33_2130	COG1454	alcohol dehydrogenase
BF33_2131	COG2610	gluconate transmembrane transporter activity
BF33_2136	COG0733	neurotransmitter:sodium symporter activity
BF33_2139	COG5002	protein histidine kinase activity
BF33_2139	COG3850	Histidine kinase
BF33_214	COG1376	ErfK ybiS ycfS ynhG family protein
BF33_2140	COG0745	RESPONSE REGULATOR receiver
BF33_2141	COG0471	metal ion transport
BF33_2142	COG1929	Belongs to the glycerate kinase type-1 family
BF33_2153	COG1674	ftsk spoiiie
BF33_2157	COG0017	Asparaginyl-tRNA synthetase
BF33_2158	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF33_216	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_2161	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF33_2165	COG0018	arginyl-trna synthetase
BF33_217	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF33_2170	COG1413	lyase activity
BF33_2171	COG3344	reverse transcriptase
BF33_2172	COG0629	single-stranded DNA binding
BF33_2175	COG0488	(ABC) transporter
BF33_2176	COG1418	mRNA catabolic process
BF33_2180	COG2359	stage V sporulation protein S
BF33_2187	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF33_2188	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF33_2189	COG2146	nitrite reductase [NAD(P)H] activity
BF33_219	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF33_2190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF33_2190	COG1587	Uroporphyrinogen-III synthase
BF33_2192	COG1648	precorrin-2 dehydrogenase activity
BF33_2194	COG2223	nitrite transmembrane transporter activity
BF33_2196	COG0314	molybdopterin synthase activity
BF33_2197	COG0303	'Molybdopterin
BF33_2198	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF33_2199	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF33_2200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF33_2203	COG1335	isochorismatase
BF33_2204	COG1764	response to oxidative stress
BF33_2205	COG4918	Iron-sulphur cluster biosynthesis
BF33_2206	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF33_2207	COG3118	belongs to the thioredoxin family
BF33_2208	COG1959	2 iron, 2 sulfur cluster binding
BF33_2210	COG2181	nitrate reductase activity
BF33_2211	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF33_2212	COG1140	nitrate reductase beta subunit
BF33_2213	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF33_2214	COG0714	Associated with various cellular activities
BF33_2215	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF33_2216	COG1305	Transglutaminase-like
BF33_2217	COG0386	Belongs to the glutathione peroxidase family
BF33_222	COG1760	l-serine dehydratase
BF33_2221	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BF33_2223	COG1595	DNA-templated transcription, initiation
BF33_2224	COG0604	alcohol dehydrogenase
BF33_2226	COG0346	lactoylglutathione lyase activity
BF33_2227	COG1082	Xylose isomerase domain protein TIM barrel
BF33_223	COG1760	l-serine dehydratase
BF33_2231	COG2226	methyltransferase
BF33_2236	COG3874	Sporulation protein YtfJ
BF33_2238	COG3344	reverse transcriptase
BF33_224	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF33_225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_2250	COG0456	acetyltransferase
BF33_2256	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_2257	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_2258	COG1819	glycosyl
BF33_226	COG0300	oxidoreductase activity
BF33_2262	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF33_2264	COG0561	phosphatase activity
BF33_2268	COG2211	Major facilitator Superfamily
BF33_2269	COG0154	amidase activity
BF33_2271	COG1876	peptidase activity
BF33_2273	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_2277	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF33_2278	COG1114	Component of the transport system for branched-chain amino acids
BF33_2281	COG1253	flavin adenine dinucleotide binding
BF33_2282	COG2839	Protein conserved in bacteria
BF33_2283	COG0702	epimerase
BF33_2286	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF33_2287	COG1607	acyl-coa hydrolase
BF33_2288	COG3689	TIGRFAM TIGR03943 family protein
BF33_2289	COG0701	Predicted permease
BF33_229	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF33_2291	COG2244	polysaccharide biosynthetic process
BF33_2292	COG0586	Pfam SNARE associated Golgi protein
BF33_2293	COG1051	belongs to the nudix hydrolase family
BF33_2294	COG5337	Spore coat protein CotH
BF33_2296	COG0406	alpha-ribazole phosphatase activity
BF33_2299	COG4166	transmembrane transport
BF33_23	COG1466	dna polymerase III delta subunit
BF33_2301	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF33_2303	COG0702	epimerase
BF33_2305	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF33_2305	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF33_231	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF33_2316	COG0456	acetyltransferase
BF33_2317	COG0523	cobalamin synthesis protein
BF33_2318	COG4989	oxidoreductase activity
BF33_2320	COG1231	oxidoreductase activity
BF33_2322	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF33_2325	COG0783	Belongs to the Dps family
BF33_2326	COG3949	Membrane
BF33_2329	COG0840	transmembrane signaling receptor activity
BF33_2334	COG2814	Major facilitator Superfamily
BF33_2335	COG0667	Aldo Keto reductase
BF33_2336	COG0640	Transcriptional regulator
BF33_2337	COG1404	Belongs to the peptidase S8 family
BF33_2338	COG2002	toxin-antitoxin pair type II binding
BF33_2339	COG0577	efflux transmembrane transporter activity
BF33_2346	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF33_2348	COG1279	arginine transmembrane transporter activity
BF33_2349	COG2814	Major facilitator Superfamily
BF33_235	COG1522	sequence-specific DNA binding
BF33_2351	COG1082	Xylose isomerase domain protein TIM barrel
BF33_2354	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_2355	COG4264	IucA IucC family
BF33_2357	COG1247	-acetyltransferase
BF33_2358	COG1285	pathogenesis
BF33_2360	COG0726	polysaccharide deacetylase
BF33_2361	COG5002	protein histidine kinase activity
BF33_2362	COG0745	RESPONSE REGULATOR receiver
BF33_2364	COG1316	TRANSCRIPTIONal
BF33_2369	COG0460	homoserine dehydrogenase
BF33_237	COG0737	Belongs to the 5'-nucleotidase family
BF33_2372	COG5658	integral membrane protein
BF33_2373	COG0726	polysaccharide deacetylase
BF33_2375	COG0300	oxidoreductase activity
BF33_2377	COG5002	protein histidine kinase activity
BF33_2378	COG0745	RESPONSE REGULATOR receiver
BF33_2379	COG1132	(ABC) transporter
BF33_2381	COG0791	NLP P60 protein
BF33_2381	COG1388	LysM domain
BF33_2383	COG1686	Belongs to the peptidase S11 family
BF33_2387	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF33_2388	COG4988	ABC transporter
BF33_2389	COG1294	oxidase, subunit
BF33_2390	COG1271	oxidase subunit
BF33_2394	COG1942	4-Oxalocrotonate Tautomerase
BF33_2396	COG0583	DNA-binding transcription factor activity
BF33_240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF33_2400	COG0411	ABC transporter
BF33_2402	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_2403	COG2030	dehydratase
BF33_2404	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_2407	COG0523	cobalamin synthesis protein
BF33_2408	COG1231	oxidoreductase activity
BF33_2409	COG0039	L-malate dehydrogenase activity
BF33_2410	COG0628	permease
BF33_2414	COG0778	Nitroreductase
BF33_2415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF33_2416	COG1959	2 iron, 2 sulfur cluster binding
BF33_2417	COG0583	DNA-binding transcription factor activity
BF33_2418	COG0697	spore germination
BF33_2419	COG4549	nuclear export factor GLE1
BF33_242	COG0156	8-amino-7-oxononanoate synthase activity
BF33_2420	COG2372	response to copper ion
BF33_2420	COG1276	copper resistance
BF33_2422	COG1114	Component of the transport system for branched-chain amino acids
BF33_2423	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF33_2429	COG2132	Multicopper oxidase
BF33_243	COG2226	methyltransferase
BF33_243	COG1073	alpha beta
BF33_2430	COG0006	proline dipeptidase activity
BF33_2436	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF33_2437	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_2439	COG2390	Transcriptional regulator
BF33_244	COG4106	trans-aconitate 2-methyltransferase activity
BF33_2444	COG0531	amino acid
BF33_2446	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF33_2449	COG1914	H( )-stimulated, divalent metal cation uptake system
BF33_245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF33_2453	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_2458	COG4166	transmembrane transport
BF33_2462	COG0427	acetyl-CoA hydrolase
BF33_2463	COG3279	Response regulator of the LytR AlgR family
BF33_2465	COG3384	dioxygenase
BF33_2466	COG2814	Major facilitator Superfamily
BF33_2471	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF33_2473	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF33_2474	COG0440	acetolactate synthase activity
BF33_2475	COG0028	Belongs to the TPP enzyme family
BF33_2476	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF33_2478	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF33_2482	COG2323	membrane
BF33_2483	COG5566	PFAM Mor transcription activator
BF33_2485	COG0733	neurotransmitter:sodium symporter activity
BF33_2486	COG2244	polysaccharide biosynthetic process
BF33_2489	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF33_249	COG0307	riboflavin synthase, alpha
BF33_2490	COG2223	nitrite transmembrane transporter activity
BF33_2491	COG4166	transmembrane transport
BF33_2492	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF33_2494	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_2495	COG0477	Major facilitator Superfamily
BF33_2497	COG1966	Carbon starvation protein
BF33_250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF33_250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF33_2502	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_2503	COG1051	belongs to the nudix hydrolase family
BF33_2513	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF33_2514	COG0784	Response regulator, receiver
BF33_2515	COG4191	Histidine kinase
BF33_2516	COG0281	malic enzyme
BF33_2517	COG1027	Aspartate ammonia-lyase
BF33_2519	COG0528	UMP kinase activity
BF33_2520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF33_2523	COG1131	(ABC) transporter
BF33_253	COG1073	alpha beta
BF33_2530	COG2733	membrane
BF33_2536	COG0785	Cytochrome C biogenesis protein
BF33_254	COG0456	acetyltransferase
BF33_2540	COG3340	Belongs to the peptidase S51 family
BF33_2541	COG0534	Mate efflux family protein
BF33_2545	COG0114	fumarate hydratase activity
BF33_2547	COG0789	Transcriptional regulator
BF33_2548	COG1757	Na H antiporter
BF33_2549	COG0438	transferase activity, transferring glycosyl groups
BF33_2549	COG1216	Glycosyl transferase, family 2
BF33_255	COG1609	Transcriptional regulator
BF33_2551	COG0701	Predicted permease
BF33_2552	COG0523	cobalamin synthesis protein
BF33_2553	COG0697	spore germination
BF33_2554	COG1802	Transcriptional regulator
BF33_256	COG2056	Na+-H+ antiporter family
BF33_2560	COG0367	asparagine synthase
BF33_2562	COG1846	Transcriptional regulator
BF33_2566	COG0406	alpha-ribazole phosphatase activity
BF33_2568	COG1686	Belongs to the peptidase S11 family
BF33_257	COG0596	Alpha beta hydrolase
BF33_2573	COG1234	tRNA 3'-trailer cleavage
BF33_2574	COG1177	transmembrane transport
BF33_2576	COG3842	ATPase activity
BF33_2582	COG2329	Antibiotic biosynthesis monooxygenase
BF33_2589	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF33_259	COG0737	Belongs to the 5'-nucleotidase family
BF33_259	COG1525	nuclease
BF33_259	COG4085	toxin activity
BF33_2590	COG4786	Flagellar basal body rod
BF33_2591	COG1419	protein localization to endoplasmic reticulum
BF33_2592	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF33_2593	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF33_2595	COG1987	bacterial-type flagellum assembly
BF33_2596	COG1338	Plays a role in the flagellum-specific transport system
BF33_2598	COG1776	CheC inhibitor of MCP methylation
BF33_2598	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF33_2599	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF33_2601	COG0741	lytic transglycosylase activity
BF33_2602	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF33_2603	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF33_2605	COG0784	Response regulator, receiver
BF33_2605	COG0835	chemotaxis
BF33_261	COG0456	acetyltransferase
BF33_261	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF33_2612	COG1157	protein secretion by the type III secretion system
BF33_2614	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF33_2615	COG1766	The M ring may be actively involved in energy transduction
BF33_2616	COG1677	Flagellar hook-basal body complex protein FliE
BF33_2617	COG1558	bacterial-type flagellum-dependent cell motility
BF33_2618	COG1815	bacterial-type flagellum-dependent cell motility
BF33_262	COG0656	L-ascorbic acid biosynthetic process
BF33_2621	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BF33_2622	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF33_2623	COG1256	bacterial-type flagellum assembly
BF33_2627	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF33_263	COG0667	Aldo Keto reductase
BF33_2630	COG1776	CheC inhibitor of MCP methylation
BF33_2630	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF33_2631	COG2198	Histidine kinase
BF33_2631	COG0643	Histidine kinase
BF33_2632	COG0643	Histidine kinase
BF33_2632	COG2198	Histidine kinase
BF33_2633	COG2201	protein-glutamate methylesterase activity
BF33_2634	COG1360	Flagellar Motor Protein
BF33_2635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF33_2637	COG1923	regulation of RNA biosynthetic process
BF33_2648	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF33_2649	COG2323	membrane
BF33_2651	COG0789	Transcriptional regulator
BF33_2651	COG4978	Transcriptional regulator
BF33_2652	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF33_2653	COG0475	glutathione-regulated potassium exporter activity
BF33_2655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF33_2656	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF33_2657	COG3162	membrane
BF33_2660	COG1280	lysine exporter protein (LysE YggA)
BF33_2661	COG3403	YqcI/YcgG family
BF33_2668	COG0328	RNA-DNA hybrid ribonuclease activity
BF33_267	COG1300	Membrane
BF33_2672	COG0454	-acetyltransferase
BF33_2675	COG0438	transferase activity, transferring glycosyl groups
BF33_2676	COG1215	transferase activity, transferring glycosyl groups
BF33_2679	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF33_268	COG0735	belongs to the Fur family
BF33_2684	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF33_2687	COG0754	glutathionylspermidine amidase activity
BF33_2692	COG0456	acetyltransferase
BF33_2694	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF33_2696	COG2311	Membrane
BF33_2697	COG2233	PERMEase
BF33_2699	COG0024	Methionine aminopeptidase
BF33_270	COG4974	Belongs to the 'phage' integrase family
BF33_2700	COG3173	Aminoglycoside phosphotransferase
BF33_2702	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF33_2703	COG1199	ATP-dependent helicase activity
BF33_2705	COG0116	Belongs to the methyltransferase superfamily
BF33_2716	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF33_2716	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF33_2718	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF33_2719	COG3935	DnaD domain protein
BF33_2723	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF33_2723	COG1199	ATP-dependent helicase activity
BF33_2730	COG0438	transferase activity, transferring glycosyl groups
BF33_2731	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF33_2734	COG1694	Mazg nucleotide pyrophosphohydrolase
BF33_2735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_2737	COG2738	Putative neutral zinc metallopeptidase
BF33_2740	COG4347	Protein of unknown function (DUF1405)
BF33_2742	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF33_2746	COG0457	Tetratricopeptide repeat
BF33_2747	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF33_275	COG0598	Magnesium transport protein CorA
BF33_2750	COG0105	UTP biosynthetic process
BF33_2751	COG0142	geranyltranstransferase activity
BF33_2753	COG0142	geranyltranstransferase activity
BF33_2756	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF33_2770	COG0252	asparaginase activity
BF33_2771	COG0492	ferredoxin-NADP+ reductase activity
BF33_2775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF33_2776	COG4862	establishment of competence for transformation
BF33_2778	COG1408	metallophosphoesterase
BF33_278	COG1846	Transcriptional regulator
BF33_2780	COG1266	CAAX protease self-immunity
BF33_2781	COG0514	ATP-dependent DNA helicase (RecQ)
BF33_2783	COG1141	Ferredoxin
BF33_2784	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF33_2786	COG4942	peptidase
BF33_2787	COG2096	Adenosyltransferase
BF33_2788	COG5002	protein histidine kinase activity
BF33_2789	COG0745	RESPONSE REGULATOR receiver
BF33_2790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF33_2791	COG1333	cytochrome c biogenesis protein
BF33_2793	COG1187	pseudouridine synthase activity
BF33_2794	COG0700	Nucleoside recognition
BF33_2795	COG2715	membrane protein required for spore maturation
BF33_2796	COG1686	Belongs to the peptidase S11 family
BF33_2797	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF33_28	COG1733	regulation of RNA biosynthetic process
BF33_2800	COG0392	lysyltransferase activity
BF33_2800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF33_2804	COG5002	protein histidine kinase activity
BF33_2805	COG0582	viral genome integration into host DNA
BF33_2807	COG1801	Protein of unknown function DUF72
BF33_2808	COG3852	Histidine kinase
BF33_281	COG1131	(ABC) transporter
BF33_2811	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF33_2812	COG1392	Phosphate transport regulator
BF33_2813	COG0306	phosphate transporter
BF33_2814	COG0730	response to heat
BF33_282	COG1725	Transcriptional regulator
BF33_2822	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF33_2824	COG1114	Component of the transport system for branched-chain amino acids
BF33_2826	COG2197	response regulator
BF33_2827	COG4585	Histidine kinase
BF33_2828	COG4758	membrane
BF33_283	COG1686	Belongs to the peptidase S11 family
BF33_2831	COG1757	Na H antiporter
BF33_2835	COG0733	neurotransmitter:sodium symporter activity
BF33_2836	COG1648	precorrin-2 dehydrogenase activity
BF33_2840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF33_2841	COG0529	Catalyzes the synthesis of activated sulfate
BF33_2845	COG0019	diaminopimelate decarboxylase activity
BF33_2847	COG1368	sulfuric ester hydrolase activity
BF33_2848	COG1183	phosphatidylcholine synthase activity
BF33_2851	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF33_2866	COG0440	acetolactate synthase activity
BF33_2867	COG0028	Belongs to the TPP enzyme family
BF33_2868	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF33_287	COG0733	neurotransmitter:sodium symporter activity
BF33_2872	COG3874	Sporulation protein YtfJ
BF33_2873	COG4709	membrane
BF33_2874	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF33_2875	COG1301	dicarboxylic acid transport
BF33_2877	COG1846	Transcriptional regulator
BF33_2880	COG1968	undecaprenyl-diphosphatase activity
BF33_2881	COG0534	Mate efflux family protein
BF33_2888	COG0716	FMN binding
BF33_2893	COG1696	Membrane protein involved in D-alanine export
BF33_2895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF33_2896	COG2070	2-Nitropropane dioxygenase
BF33_2897	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF33_2899	COG1335	isochorismatase
BF33_29	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF33_2901	COG1522	sequence-specific DNA binding
BF33_2903	COG1266	CAAX protease self-immunity
BF33_2904	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF33_2905	COG1131	(ABC) transporter
BF33_2907	COG1131	(ABC) transporter
BF33_2908	COG1725	Transcriptional regulator
BF33_2909	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF33_2910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF33_2912	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF33_2913	COG1780	Probably involved in ribonucleotide reductase function
BF33_2919	COG4873	Protein conserved in bacteria
BF33_292	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_2922	COG0720	synthase
BF33_2924	COG5002	protein histidine kinase activity
BF33_2926	COG2318	DinB family
BF33_2928	COG1846	Transcriptional regulator
BF33_2929	COG3852	Histidine kinase
BF33_2931	COG2861	carbohydrate metabolic process
BF33_2933	COG0235	Class ii aldolase
BF33_2936	COG1349	DNA-binding transcription factor activity
BF33_2939	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF33_2941	COG3842	ATPase activity
BF33_2942	COG1840	ABC-type Fe3 transport system, periplasmic component
BF33_2945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF33_2947	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF33_2948	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_295	COG0697	spore germination
BF33_2952	COG2030	dehydratase
BF33_2954	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF33_2955	COG0861	Integral membrane protein TerC family
BF33_2956	COG2116	formate transmembrane transporter activity
BF33_2958	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF33_296	COG0561	phosphatase activity
BF33_2962	COG2186	Transcriptional regulator
BF33_2963	COG5002	protein histidine kinase activity
BF33_2964	COG0745	RESPONSE REGULATOR receiver
BF33_2966	COG3835	regulator
BF33_2967	COG0277	FAD linked oxidase domain protein
BF33_2968	COG0247	lactate metabolic process
BF33_2969	COG2340	Cysteine-rich secretory protein family
BF33_297	COG4086	secreted protein
BF33_2971	COG0564	pseudouridine synthase activity
BF33_2973	COG2409	Drug exporters of the RND superfamily
BF33_2975	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF33_2976	COG1177	transmembrane transport
BF33_2977	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF33_2979	COG1012	belongs to the aldehyde dehydrogenase family
BF33_298	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF33_2985	COG0681	Belongs to the peptidase S26 family
BF33_2986	COG1686	Belongs to the peptidase S11 family
BF33_2988	COG2226	methyltransferase
BF33_299	COG0456	acetyltransferase
BF33_2991	COG4974	Belongs to the 'phage' integrase family
BF33_2995	COG4695	Portal protein
BF33_3	COG0778	Nitroreductase
BF33_300	COG1547	Domain of unknown function (DUF309)
BF33_3022	COG1476	TRANSCRIPTIONal
BF33_3024	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF33_3036	COG5634	Uncharacterized conserved protein (DUF2278)
BF33_3037	COG1620	l-lactate permease
BF33_3044	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF33_3044	COG0512	Glutamine amidotransferase of anthranilate synthase
BF33_3046	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF33_3047	COG5492	domain, Protein
BF33_305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF33_3050	COG2382	esterase
BF33_3052	COG2153	protein acetylation
BF33_3060	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF33_3063	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF33_3067	COG0463	Glycosyl transferase, family 2
BF33_3067	COG0457	Tetratricopeptide repeat
BF33_3071	COG1216	Glycosyl transferase, family 2
BF33_3072	COG0772	Belongs to the SEDS family
BF33_3075	COG0564	pseudouridine synthase activity
BF33_3077	COG2357	RelA SpoT domain protein
BF33_3079	COG4116	CYTH
BF33_3080	COG2346	COG2346, Truncated hemoglobins
BF33_3083	COG1164	Oligoendopeptidase f
BF33_3085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF33_3086	COG4862	establishment of competence for transformation
BF33_3087	COG0861	Integral membrane protein TerC family
BF33_3088	COG1393	Belongs to the ArsC family
BF33_309	COG3711	transcriptional antiterminator
BF33_3090	COG4166	transmembrane transport
BF33_3091	COG0534	Mate efflux family protein
BF33_3092	COG4608	Belongs to the ABC transporter superfamily
BF33_3093	COG0444	Belongs to the ABC transporter superfamily
BF33_3094	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF33_3095	COG0601	transmembrane transport
BF33_3096	COG4166	transmembrane transport
BF33_3098	COG0180	Tryptophanyl-tRNA synthetase
BF33_31	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF33_310	COG1263	PTS System
BF33_310	COG2190	(PTS) system
BF33_310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF33_3100	COG5504	Zn-dependent protease
BF33_3101	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF33_3102	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_3105	COG2267	carboxylic ester hydrolase activity
BF33_3107	COG0542	response to heat
BF33_3109	COG0561	phosphatase activity
BF33_3112	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_3114	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF33_3116	COG2996	Protein conserved in bacteria
BF33_3120	COG0004	ammonium transporteR
BF33_3121	COG0753	catalase activity
BF33_3123	COG0367	asparagine synthase
BF33_3128	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF33_3140	COG0398	Pfam SNARE associated Golgi protein
BF33_3142	COG4903	ComK protein
BF33_3146	COG1278	Cold shock
BF33_3148	COG2224	Isocitrate lyase
BF33_3149	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF33_315	COG0778	Nitroreductase
BF33_3150	COG0497	DNA recombination
BF33_3153	COG0697	spore germination
BF33_3154	COG0501	Belongs to the peptidase M48B family
BF33_3159	COG0745	RESPONSE REGULATOR receiver
BF33_316	COG3706	GGDEF domain
BF33_3160	COG2205	protein histidine kinase activity
BF33_3163	COG3708	Transcriptional regulator
BF33_3163	COG2207	Transcriptional regulator
BF33_3164	COG1595	DNA-templated transcription, initiation
BF33_3166	COG1078	dGTPase activity
BF33_3168	COG1408	metallophosphoesterase
BF33_317	COG2084	Dehydrogenase
BF33_3176	COG3209	COG3209 Rhs family protein
BF33_3179	COG3209	COG3209 Rhs family protein
BF33_3188	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_3190	COG0095	Lipoate-protein ligase
BF33_3191	COG1234	tRNA 3'-trailer cleavage
BF33_3193	COG1609	Transcriptional regulator
BF33_3194	COG2378	regulation of single-species biofilm formation
BF33_3196	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BF33_3200	COG1511	domain protein
BF33_3201	COG1309	transcriptional regulator
BF33_3210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF33_3211	COG2329	Antibiotic biosynthesis monooxygenase
BF33_3212	COG3428	Bacterial PH domain
BF33_3213	COG3402	PFAM membrane-flanked domain
BF33_3221	COG3428	Bacterial PH domain
BF33_3222	COG3402	PFAM membrane-flanked domain
BF33_3224	COG1309	transcriptional regulator
BF33_3235	COG4473	ABC transporter
BF33_3236	COG1131	(ABC) transporter
BF33_3237	COG0537	adenosine 5'-monophosphoramidase activity
BF33_3238	COG4980	gas vesicle protein
BF33_324	COG0436	Aminotransferase
BF33_3242	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF33_3243	COG3973	AAA domain
BF33_3245	COG0477	Major facilitator Superfamily
BF33_3246	COG0477	Major facilitator Superfamily
BF33_3249	COG0772	Belongs to the SEDS family
BF33_325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF33_3253	COG2801	Transposase and inactivated derivatives
BF33_3254	COG2963	transposase activity
BF33_3255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF33_3257	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF33_3258	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF33_3262	COG2267	carboxylic ester hydrolase activity
BF33_3264	COG0457	Tetratricopeptide repeat
BF33_3265	COG0346	lactoylglutathione lyase activity
BF33_3266	COG0346	lactoylglutathione lyase activity
BF33_3269	COG5444	nuclease activity
BF33_3273	COG4717	serine-type aminopeptidase activity
BF33_3274	COG0420	3'-5' exonuclease activity
BF33_3283	COG0393	Putative heavy-metal-binding
BF33_3288	COG2198	Histidine kinase
BF33_3288	COG0784	Response regulator, receiver
BF33_3288	COG2205	protein histidine kinase activity
BF33_3288	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF33_3289	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF33_329	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_3290	COG2208	phosphoserine phosphatase activity
BF33_3292	COG1191	sigma factor activity
BF33_3297	COG3237	CsbD-like
BF33_330	COG1695	Transcriptional regulator
BF33_3307	COG2770	Histidine kinase
BF33_3307	COG3437	response regulator, receiver
BF33_3309	COG2376	Dihydroxyacetone kinase
BF33_3311	COG2376	Dihydroxyacetone kinase
BF33_3317	COG1183	phosphatidylcholine synthase activity
BF33_3333	COG0477	Major facilitator Superfamily
BF33_3337	COG0305	Participates in initiation and elongation during chromosome replication
BF33_3348	COG0494	nUDIX hydrolase
BF33_3349	COG3181	Tripartite tricarboxylate transporter family receptor
BF33_3350	COG4565	transcriptional regulatory protein
BF33_3351	COG3290	protein histidine kinase activity
BF33_3352	COG0477	Major facilitator Superfamily
BF33_3355	COG4608	Belongs to the ABC transporter superfamily
BF33_3356	COG0444	Belongs to the ABC transporter superfamily
BF33_3357	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF33_3358	COG0601	transmembrane transport
BF33_3365	COG3938	Belongs to the proline racemase family
BF33_3369	COG1363	Peptidase, m42
BF33_337	COG0183	Belongs to the thiolase family
BF33_3373	COG1024	Enoyl-CoA hydratase
BF33_3376	COG1696	Membrane protein involved in D-alanine export
BF33_3380	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_3382	COG2244	polysaccharide biosynthetic process
BF33_3383	COG0653	protein targeting
BF33_3387	COG0659	secondary active sulfate transmembrane transporter activity
BF33_3390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF33_3391	COG3409	Peptidoglycan-binding domain 1 protein
BF33_3391	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF33_3393	COG0561	phosphatase activity
BF33_3395	COG3527	Alpha-acetolactate decarboxylase
BF33_3396	COG0028	Belongs to the TPP enzyme family
BF33_3402	COG0189	ligase activity
BF33_3405	COG1126	abc transporter atp-binding protein
BF33_3406	COG0765	amino acid transport
BF33_3407	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF33_3408	COG1132	(ABC) transporter
BF33_3409	COG1132	(ABC) transporter
BF33_3410	COG1012	belongs to the aldehyde dehydrogenase family
BF33_3412	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF33_3413	COG0531	amino acid
BF33_3415	COG0693	protein deglycase activity
BF33_3415	COG0753	catalase activity
BF33_3416	COG0693	protein deglycase activity
BF33_3418	COG2211	Major facilitator Superfamily
BF33_3419	COG4533	DNA binding
BF33_3421	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF33_3423	COG1733	regulation of RNA biosynthetic process
BF33_3424	COG2814	Major facilitator Superfamily
BF33_3425	COG1309	transcriptional regulator
BF33_3426	COG2076	Multidrug Resistance protein
BF33_3427	COG2076	Multidrug Resistance protein
BF33_3429	COG1522	sequence-specific DNA binding
BF33_3433	COG2259	Doxx family
BF33_3435	COG1263	PTS System
BF33_3435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF33_3437	COG1737	Transcriptional regulator
BF33_3439	COG0475	glutathione-regulated potassium exporter activity
BF33_3440	COG0531	amino acid
BF33_3447	COG0586	Pfam SNARE associated Golgi protein
BF33_345	COG3842	ATPase activity
BF33_3454	COG3546	catalase activity
BF33_3455	COG1114	Component of the transport system for branched-chain amino acids
BF33_3458	COG5522	Integral membrane protein (intg_mem_TP0381)
BF33_346	COG0366	Alpha amylase catalytic
BF33_3460	COG1136	(ABC) transporter
BF33_3461	COG0577	efflux transmembrane transporter activity
BF33_3462	COG1388	LysM domain
BF33_3462	COG3584	3D domain protein
BF33_3466	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF33_3467	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF33_3468	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF33_3468	COG3711	transcriptional antiterminator
BF33_3471	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF33_3472	COG0604	alcohol dehydrogenase
BF33_3473	COG1316	TRANSCRIPTIONal
BF33_3475	COG0730	response to heat
BF33_3476	COG2210	Belongs to the sulfur carrier protein TusA family
BF33_3478	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_3479	COG0425	Belongs to the sulfur carrier protein TusA family
BF33_348	COG2182	Extracellular solute-binding protein
BF33_3480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_3480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_3481	COG0425	Belongs to the sulfur carrier protein TusA family
BF33_3481	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_3482	COG1937	Protein conserved in bacteria
BF33_3483	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF33_3485	COG3591	Belongs to the peptidase S1B family
BF33_3487	COG2719	SpoVR family
BF33_3488	COG0778	Nitroreductase
BF33_349	COG1175	transmembrane transport
BF33_3495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF33_3496	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_3499	COG1376	ErfK ybiS ycfS ynhG family protein
BF33_35	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF33_350	COG3833	ABC-type maltose transport systems, permease component
BF33_3500	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_3501	COG2252	PERMEase
BF33_3504	COG1846	Transcriptional regulator
BF33_3505	COG2814	Major facilitator Superfamily
BF33_3506	COG2205	protein histidine kinase activity
BF33_351	COG1609	Transcriptional regulator
BF33_3513	COG0351	phosphomethylpyrimidine kinase
BF33_3514	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF33_3516	COG2104	thiamine diphosphate biosynthetic process
BF33_3517	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF33_3518	COG0352	thiamine-phosphate diphosphorylase activity
BF33_3519	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF33_352	COG0436	Aminotransferase
BF33_3520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF33_3521	COG1116	anion transmembrane transporter activity
BF33_3522	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF33_3526	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF33_354	COG2205	protein histidine kinase activity
BF33_3551	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF33_3552	COG0581	inorganic phosphate transmembrane transporter activity
BF33_3553	COG0573	inorganic phosphate transmembrane transporter activity
BF33_3554	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF33_3555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF33_3555	COG1918	ferrous iron import across plasma membrane
BF33_3556	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF33_3557	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF33_3559	COG0531	amino acid
BF33_356	COG3209	COG3209 Rhs family protein
BF33_3560	COG0697	spore germination
BF33_3561	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF33_3564	COG4990	cell redox homeostasis
BF33_3565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF33_3566	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF33_3569	COG0569	domain protein
BF33_3569	COG0475	glutathione-regulated potassium exporter activity
BF33_3571	COG2153	protein acetylation
BF33_3574	COG2252	PERMEase
BF33_3575	COG1113	amino acid transport
BF33_3578	COG1114	Component of the transport system for branched-chain amino acids
BF33_3579	COG3104	oligopeptide transport
BF33_3582	COG1476	TRANSCRIPTIONal
BF33_3583	COG3583	domain protein
BF33_3583	COG3584	3D domain protein
BF33_3584	COG0840	transmembrane signaling receptor activity
BF33_3590	COG3568	Endonuclease Exonuclease Phosphatase
BF33_3593	COG1063	alcohol dehydrogenase
BF33_3596	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF33_3597	COG1879	ABC-type sugar transport system periplasmic component
BF33_3598	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF33_3599	COG1129	ABC transporter
BF33_36	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF33_360	COG2814	Major facilitator Superfamily
BF33_3601	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF33_3602	COG1609	Transcriptional regulator
BF33_3603	COG0477	Major facilitator Superfamily
BF33_3604	COG1846	Transcriptional regulator
BF33_3605	COG2271	Major facilitator Superfamily
BF33_3607	COG4608	Belongs to the ABC transporter superfamily
BF33_3608	COG0601	transmembrane transport
BF33_3610	COG0747	negative chemotaxis
BF33_3613	COG0659	secondary active sulfate transmembrane transporter activity
BF33_3616	COG5002	protein histidine kinase activity
BF33_3617	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF33_3618	COG2378	regulation of single-species biofilm formation
BF33_3620	COG1595	DNA-templated transcription, initiation
BF33_3623	COG0833	amino acid
BF33_3624	COG0765	amino acid transport
BF33_3625	COG0765	amino acid transport
BF33_3626	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF33_3627	COG1126	abc transporter atp-binding protein
BF33_3628	COG1115	amino acid carrier protein
BF33_3629	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF33_3631	COG0697	spore germination
BF33_3634	COG0366	Alpha amylase catalytic
BF33_3635	COG1263	PTS System
BF33_3635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF33_3636	COG2188	Transcriptional regulator
BF33_3637	COG0531	amino acid
BF33_3641	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF33_3642	COG0714	Associated with various cellular activities
BF33_3643	COG4548	von Willebrand factor, type A
BF33_3645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF33_3646	COG0156	8-amino-7-oxononanoate synthase activity
BF33_3648	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_3649	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_3650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_3651	COG3104	oligopeptide transport
BF33_3654	COG1620	l-lactate permease
BF33_3655	COG1027	Aspartate ammonia-lyase
BF33_3656	COG1253	flavin adenine dinucleotide binding
BF33_3657	COG0346	lactoylglutathione lyase activity
BF33_3658	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_3659	COG1316	TRANSCRIPTIONal
BF33_3660	COG2720	vancomycin resistance protein
BF33_3664	COG3227	Zinc metalloprotease (Elastase)
BF33_3667	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF33_3668	COG2217	Heavy metal translocating P-type atpase
BF33_3669	COG0640	Transcriptional regulator
BF33_367	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF33_3670	COG0531	amino acid
BF33_3673	COG2427	Protein of unknown function (DUF1641)
BF33_3674	COG3383	formate dehydrogenase (NAD+) activity
BF33_3675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF33_3676	COG0456	acetyltransferase
BF33_3676	COG0454	-acetyltransferase
BF33_3678	COG0745	RESPONSE REGULATOR receiver
BF33_3679	COG5002	protein histidine kinase activity
BF33_3681	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_3684	COG0281	malic enzyme
BF33_3685	COG3493	citrate carrier protein
BF33_3686	COG4565	transcriptional regulatory protein
BF33_3687	COG3290	protein histidine kinase activity
BF33_3689	COG4990	cell redox homeostasis
BF33_369	COG1408	metallophosphoesterase
BF33_3691	COG5002	protein histidine kinase activity
BF33_3692	COG0745	RESPONSE REGULATOR receiver
BF33_3693	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF33_3695	COG0395	ABC-type sugar transport system, permease component
BF33_3696	COG1175	transmembrane transport
BF33_3697	COG3842	ATPase activity
BF33_3698	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF33_370	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_3702	COG2851	Citrate transporter
BF33_3703	COG4565	transcriptional regulatory protein
BF33_3704	COG3290	protein histidine kinase activity
BF33_3706	COG2268	Band 7 protein
BF33_3707	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF33_3709	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF33_371	COG2200	EAL domain
BF33_3735	COG1802	Transcriptional regulator
BF33_3735	COG4626	Terminase
BF33_374	COG4703	Protein of unknown function (DUF1797)
BF33_3740	COG0582	viral genome integration into host DNA
BF33_3741	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF33_3750	COG0756	dUTP diphosphatase activity
BF33_3755	COG0305	Participates in initiation and elongation during chromosome replication
BF33_376	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF33_3763	COG1396	sequence-specific DNA binding
BF33_3769	COG2766	serine protein kinase
BF33_3772	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF33_3774	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF33_3776	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF33_3777	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF33_378	COG0517	IMP dehydrogenase activity
BF33_379	COG0583	DNA-binding transcription factor activity
BF33_38	COG1610	YqeY-like protein
BF33_3801	COG0735	belongs to the Fur family
BF33_3802	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF33_3806	COG4555	ABC transporter
BF33_3808	COG0070	glutamate synthase
BF33_3808	COG0067	glutamate synthase
BF33_3808	COG0069	glutamate synthase activity
BF33_3809	COG4129	membrane
BF33_3810	COG1132	(ABC) transporter
BF33_3815	COG1194	a g-specific adenine glycosylase
BF33_3816	COG1988	membrane-bound metal-dependent
BF33_3822	COG1090	epimerase
BF33_3823	COG1228	amidohydrolase
BF33_3827	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF33_383	COG0569	domain protein
BF33_3830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF33_3830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF33_3832	COG0463	Glycosyl transferase, family 2
BF33_3835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF33_3836	COG1263	PTS System
BF33_3836	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF33_3837	COG2066	Belongs to the glutaminase family
BF33_384	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF33_3842	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF33_3844	COG0101	tRNA pseudouridine synthase activity
BF33_3845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF33_3846	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF33_3850	COG0535	radical SAM domain protein
BF33_3852	COG0387	Pfam Sodium calcium exchanger
BF33_3853	COG3871	stress protein (general stress protein 26)
BF33_3856	COG0586	Pfam SNARE associated Golgi protein
BF33_386	COG0561	phosphatase activity
BF33_3861	COG0697	spore germination
BF33_3862	COG2217	Heavy metal translocating P-type atpase
BF33_3863	COG1295	ribonuclease BN
BF33_3865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF33_3868	COG3853	Toxic anion resistance protein (TelA)
BF33_387	COG0242	peptide deformylase activity
BF33_3870	COG0861	Integral membrane protein TerC family
BF33_3871	COG2310	stress, protein
BF33_3872	COG2310	stress, protein
BF33_3873	COG2310	stress, protein
BF33_3879	COG2270	Major facilitator Superfamily
BF33_389	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF33_3890	COG0488	(ABC) transporter
BF33_3891	COG1116	anion transmembrane transporter activity
BF33_3893	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF33_3896	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF33_390	COG0022	dehydrogenase e1 component
BF33_3902	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF33_3902	COG2190	(PTS) system
BF33_3902	COG1263	PTS System
BF33_3903	COG0366	Alpha amylase catalytic
BF33_3911	COG0840	transmembrane signaling receptor activity
BF33_3913	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF33_3914	COG0765	amino acid transport
BF33_3916	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF33_3916	COG0723	plastoquinol--plastocyanin reductase activity
BF33_3917	COG2814	Major facilitator Superfamily
BF33_3918	COG3541	Predicted nucleotidyltransferase
BF33_3928	COG0166	Belongs to the GPI family
BF33_3931	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_3932	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_3933	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_3934	COG0235	Class ii aldolase
BF33_3936	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF33_3937	COG0450	alkyl hydroperoxide reductase
BF33_3940	COG1473	amidohydrolase
BF33_3946	COG4807	Protein conserved in bacteria
BF33_3948	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF33_3949	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF33_3950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_3953	COG2309	aminopeptidase activity
BF33_3954	COG2076	Multidrug Resistance protein
BF33_3955	COG1012	belongs to the aldehyde dehydrogenase family
BF33_3957	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF33_3958	COG0546	phosphoglycolate phosphatase activity
BF33_3959	COG1597	lipid kinase activity
BF33_3963	COG4682	membrane
BF33_3964	COG1846	Transcriptional regulator
BF33_3965	COG0003	Pfam Anion-transporting ATPase
BF33_3968	COG1464	Belongs to the NlpA lipoprotein family
BF33_3969	COG2011	ABC-type metal ion transport system permease component
BF33_3970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF33_3971	COG1335	isochorismatase
BF33_3975	COG4851	CamS sex pheromone cAM373 precursor
BF33_3977	COG0210	DNA helicase
BF33_3982	COG0151	Belongs to the GarS family
BF33_3984	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF33_3986	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF33_3989	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF33_3991	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF33_3992	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF33_3993	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF33_3999	COG0697	spore germination
BF33_400	COG1982	Orn Lys Arg decarboxylase major
BF33_4004	COG0745	RESPONSE REGULATOR receiver
BF33_4005	COG2205	protein histidine kinase activity
BF33_4013	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF33_4019	COG5002	protein histidine kinase activity
BF33_4021	COG2252	PERMEase
BF33_4025	COG1266	CAAX protease self-immunity
BF33_4028	COG0488	(ABC) transporter
BF33_4029	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF33_4030	COG0456	acetyltransferase
BF33_4031	COG1214	PFAM Peptidase M22, glycoprotease
BF33_4032	COG0802	atpase or kinase
BF33_404	COG0483	inositol monophosphate 1-phosphatase activity
BF33_4051	COG2183	response to ionizing radiation
BF33_4052	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF33_4053	COG0864	Transcriptional regulator
BF33_4054	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF33_4055	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF33_4057	COG4294	response to UV
BF33_4058	COG0457	Tetratricopeptide repeat
BF33_4058	COG0705	Rhomboid family
BF33_4060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF33_4062	COG2814	Major facilitator Superfamily
BF33_4064	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF33_4065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF33_4071	COG0561	phosphatase activity
BF33_4072	COG4608	Belongs to the ABC transporter superfamily
BF33_4073	COG0444	Belongs to the ABC transporter superfamily
BF33_4074	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF33_4075	COG0601	transmembrane transport
BF33_4076	COG0747	negative chemotaxis
BF33_4079	COG0842	Transport permease protein
BF33_4080	COG1511	domain protein
BF33_4080	COG0842	Transport permease protein
BF33_4081	COG1131	(ABC) transporter
BF33_4082	COG2197	response regulator
BF33_4083	COG4585	Histidine kinase
BF33_4084	COG0488	(ABC) transporter
BF33_4088	COG5298	Protein conserved in bacteria
BF33_4089	COG0084	hydrolase, TatD family'
BF33_409	COG4896	Protein conserved in bacteria
BF33_4092	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_4094	COG1609	Transcriptional regulator
BF33_4096	COG0204	Acyl-transferase
BF33_4099	COG0697	spore germination
BF33_41	COG1702	phosphate starvation-inducible protein PhoH
BF33_4103	COG1910	domain protein
BF33_4104	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF33_4105	COG4149	molybdate abc transporter
BF33_4108	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF33_4109	COG0656	L-ascorbic acid biosynthetic process
BF33_411	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF33_4110	COG4166	transmembrane transport
BF33_4111	COG4166	transmembrane transport
BF33_4113	COG1309	transcriptional regulator
BF33_4115	COG2207	Transcriptional regulator
BF33_4117	COG4166	transmembrane transport
BF33_4118	COG4608	Belongs to the ABC transporter superfamily
BF33_4119	COG0444	Belongs to the ABC transporter superfamily
BF33_412	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF33_4120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF33_4121	COG0601	transmembrane transport
BF33_4124	COG2814	Major facilitator Superfamily
BF33_4126	COG2271	Major facilitator Superfamily
BF33_4127	COG0277	FAD linked oxidase domain protein
BF33_4130	COG1464	Belongs to the NlpA lipoprotein family
BF33_4131	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF33_4132	COG2011	ABC-type metal ion transport system permease component
BF33_4133	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_4139	COG1506	peptidase
BF33_4139	COG4946	Tricorn protease homolog
BF33_4139	COG0823	Involved in the tonB-independent uptake of proteins
BF33_414	COG0772	Belongs to the SEDS family
BF33_4140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF33_4144	COG0596	Alpha beta hydrolase
BF33_4148	COG4856	YbbR-like protein
BF33_4149	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF33_415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF33_4166	COG0726	polysaccharide deacetylase
BF33_4167	COG2194	sulfuric ester hydrolase activity
BF33_4169	COG0489	protein tyrosine kinase activity
BF33_4170	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_4174	COG0101	tRNA pseudouridine synthase activity
BF33_4175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF33_4176	COG1122	ATPase activity
BF33_4182	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF33_4184	COG0024	Methionine aminopeptidase
BF33_4186	COG0201	protein transport
BF33_4191	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF33_42	COG1480	7TM receptor with intracellular HD hydrolase
BF33_4212	COG1358	cellular component organization or biogenesis
BF33_4215	COG2813	Specifically methylates the guanine in position
BF33_422	COG3336	cytochrome c oxidase
BF33_4220	COG0250	Participates in transcription elongation, termination and antitermination
BF33_4221	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF33_4223	COG3688	RNA-binding protein containing a PIN domain
BF33_4224	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF33_4227	COG1045	serine acetyltransferase
BF33_4231	COG4956	integral membrane protein (PIN domain superfamily)
BF33_4233	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF33_4234	COG0542	response to heat
BF33_4236	COG3880	PFAM UvrB UvrC protein
BF33_424	COG3344	reverse transcriptase
BF33_4256	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF33_4257	COG1396	sequence-specific DNA binding
BF33_4258	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF33_4259	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF33_4260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF33_4261	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF33_4262	COG0512	Glutamine amidotransferase of anthranilate synthase
BF33_4263	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF33_4264	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF33_4267	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF33_427	COG2340	Cysteine-rich secretory protein family
BF33_4270	COG2208	phosphoserine phosphatase activity
BF33_4273	COG1098	S1 RNA binding domain
BF33_4277	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF33_4278	COG3956	TIGRFAM MazG family protein
BF33_4279	COG2244	polysaccharide biosynthetic process
BF33_4280	COG2002	toxin-antitoxin pair type II binding
BF33_4281	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF33_4284	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF33_4287	COG0251	oxidation-reduction process
BF33_4288	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF33_4291	COG4466	Protein conserved in bacteria
BF33_4294	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF33_4295	COG0084	hydrolase, TatD family'
BF33_4296	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF33_4296	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF33_4297	COG2002	toxin-antitoxin pair type II binding
BF33_4298	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF33_430	COG0406	alpha-ribazole phosphatase activity
BF33_4300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF33_4302	COG1774	PSP1 C-terminal conserved region
BF33_4303	COG0470	DNA polymerase III
BF33_4305	COG1982	Orn Lys Arg decarboxylase major
BF33_431	COG3679	Belongs to the UPF0342 family
BF33_4317	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF33_4318	COG0590	tRNA wobble adenosine to inosine editing
BF33_4319	COG1335	isochorismatase
BF33_4320	COG1428	Deoxynucleoside kinase
BF33_4321	COG1428	Deoxynucleoside kinase
BF33_4327	COG1686	Belongs to the peptidase S11 family
BF33_4328	COG0516	GMP reductase activity
BF33_4328	COG0517	IMP dehydrogenase activity
BF33_4336	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF33_4337	COG0187	DNA topoisomerase II activity
BF33_4339	COG2501	S4 domain
BF33_434	COG0742	ribosomal rna small subunit methyltransferase
BF33_4340	COG0592	DNA-directed DNA polymerase activity
BF33_4344	COG0706	membrane insertase activity
BF33_4345	COG1847	R3H domain protein
BF33_4346	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF33_435	COG3314	Sporulation integral membrane protein YlbJ
BF33_4350	COG1192	Involved in chromosome partitioning
BF33_4351	COG1475	DNA binding
BF33_4353	COG0668	transmembrane transport
BF33_4354	COG4481	Protein conserved in bacteria
BF33_4355	COG0012	GTP binding
BF33_4357	COG0629	single-stranded DNA binding
BF33_4359	COG4241	membrane
BF33_4360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF33_4362	COG0305	Participates in initiation and elongation during chromosome replication
BF33_4368	COG0745	RESPONSE REGULATOR receiver
BF33_4369	COG5002	protein histidine kinase activity
BF33_437	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF33_4370	COG4863	YycH protein
BF33_4371	COG4853	Protein conserved in bacteria
BF33_4372	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF33_4373	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF33_4377	COG1164	Oligoendopeptidase f
BF33_438	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF33_4382	COG1272	protein, Hemolysin III
BF33_4383	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF33_4387	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF33_4388	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF33_4389	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF33_4390	COG2814	Major facilitator Superfamily
BF33_4391	COG3275	phosphorelay sensor kinase activity
BF33_4392	COG3279	Response regulator of the LytR AlgR family
BF33_4395	COG0628	permease
BF33_4396	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF33_4396	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF33_4397	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF33_4398	COG1309	transcriptional regulator
BF33_4399	COG0463	Glycosyl transferase, family 2
BF33_44	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF33_440	COG1399	metal-binding, possibly nucleic acid-binding protein
BF33_4403	COG0488	(ABC) transporter
BF33_4406	COG1607	acyl-coa hydrolase
BF33_4408	COG0840	transmembrane signaling receptor activity
BF33_4413	COG0477	Major facilitator Superfamily
BF33_4414	COG3279	Response regulator of the LytR AlgR family
BF33_4415	COG1966	Carbon starvation protein
BF33_4416	COG2879	small protein
BF33_4417	COG3706	GGDEF domain
BF33_4418	COG0351	phosphomethylpyrimidine kinase
BF33_4419	COG4585	Histidine kinase
BF33_4419	COG2203	Gaf domain
BF33_4420	COG2197	response regulator
BF33_4422	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF33_4423	COG1011	Hydrolase
BF33_4427	COG0460	homoserine dehydrogenase
BF33_4429	COG1609	Transcriptional regulator
BF33_4430	COG2755	lipolytic protein G-D-S-L family
BF33_4431	COG1131	(ABC) transporter
BF33_4432	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF33_4434	COG2814	Major facilitator Superfamily
BF33_4435	COG0561	phosphatase activity
BF33_4436	COG2233	PERMEase
BF33_4437	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF33_4439	COG2363	Small membrane protein
BF33_444	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF33_4441	COG3773	Cell wall hydrolase
BF33_4444	COG0280	phosphate acetyltransferase
BF33_4446	COG0095	Lipoate-protein ligase
BF33_4450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_4451	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_4452	COG1120	ATPase activity
BF33_4453	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_4454	COG1078	dGTPase activity
BF33_4456	COG1994	Peptidase M50
BF33_4458	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF33_4459	COG0584	glycerophosphoryl diester phosphodiesterase
BF33_4460	COG0789	Transcriptional regulator
BF33_4461	COG2814	Major facilitator Superfamily
BF33_4462	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF33_4463	COG0010	Belongs to the arginase family
BF33_4466	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF33_4467	COG4506	Protein conserved in bacteria
BF33_4469	COG1595	DNA-templated transcription, initiation
BF33_447	COG4839	cell division protein FtsL
BF33_4473	COG2234	aminopeptidase activity
BF33_4475	COG0024	Methionine aminopeptidase
BF33_4476	COG1131	(ABC) transporter
BF33_4477	COG2197	response regulator
BF33_4480	COG5001	Diguanylate cyclase
BF33_4480	COG3300	MHYT domain
BF33_4482	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF33_4483	COG2181	nitrate reductase activity
BF33_4483	COG0247	lactate metabolic process
BF33_4484	COG0183	Belongs to the thiolase family
BF33_4485	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF33_4486	COG1960	acyl-CoA dehydrogenase activity
BF33_4487	COG1960	acyl-CoA dehydrogenase activity
BF33_449	COG0768	penicillin binding
BF33_4491	COG4821	SIS domain
BF33_4494	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF33_4495	COG1494	fructose-1,6-bisphosphatase
BF33_4496	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF33_4499	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF33_45	COG0295	cytidine deaminase activity
BF33_450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF33_4500	COG2890	protein-(glutamine-N5) methyltransferase activity
BF33_4503	COG0009	L-threonylcarbamoyladenylate synthase
BF33_4506	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF33_4507	COG2259	Doxx family
BF33_4508	COG2190	(PTS) system
BF33_4510	COG0698	ribose 5-phosphate isomerase
BF33_4516	COG0356	it plays a direct role in the translocation of protons across the membrane
BF33_4526	COG5001	Diguanylate cyclase
BF33_4526	COG3300	MHYT domain
BF33_4527	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF33_4529	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF33_453	COG0772	Belongs to the SEDS family
BF33_4533	COG0839	Belongs to the complex I subunit 6 family
BF33_4535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF33_4536	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF33_4537	COG1007	ATP synthesis coupled electron transport
BF33_4538	COG4836	Membrane
BF33_454	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF33_4540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF33_4541	COG2385	sporulation resulting in formation of a cellular spore
BF33_4542	COG3279	Response regulator of the LytR AlgR family
BF33_4545	COG0739	heme binding
BF33_4546	COG0726	polysaccharide deacetylase
BF33_4546	COG1649	PFAM Uncharacterised BCR, COG1649
BF33_4547	COG1609	Transcriptional regulator
BF33_4549	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BF33_455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF33_4550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF33_4551	COG0463	Glycosyl transferase, family 2
BF33_4551	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF33_4552	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF33_4553	COG1682	transport, permease protein
BF33_4554	COG1134	teichoic acid transport
BF33_4555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF33_4555	COG1215	transferase activity, transferring glycosyl groups
BF33_4556	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF33_4559	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF33_456	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF33_4560	COG0745	RESPONSE REGULATOR receiver
BF33_4561	COG5002	protein histidine kinase activity
BF33_4566	COG1136	(ABC) transporter
BF33_4567	COG0577	efflux transmembrane transporter activity
BF33_457	COG0849	cell division
BF33_4570	COG1191	sigma factor activity
BF33_4576	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF33_4577	COG4715	Zinc finger, swim domain protein
BF33_458	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF33_4582	COG1388	LysM domain
BF33_4582	COG3584	3D domain protein
BF33_4583	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF33_4585	COG1215	transferase activity, transferring glycosyl groups
BF33_4587	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_4588	COG1388	LysM domain
BF33_4588	COG0791	NLP P60 protein
BF33_4590	COG1368	sulfuric ester hydrolase activity
BF33_4592	COG2389	metal-binding protein
BF33_4594	COG1620	l-lactate permease
BF33_4596	COG1620	l-lactate permease
BF33_4598	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF33_4599	COG1294	oxidase, subunit
BF33_46	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF33_460	COG1191	sigma factor activity
BF33_4600	COG1271	oxidase subunit
BF33_4602	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF33_4603	COG0583	DNA-binding transcription factor activity
BF33_4604	COG1511	domain protein
BF33_4605	COG0346	lactoylglutathione lyase activity
BF33_4607	COG1301	dicarboxylic acid transport
BF33_4608	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF33_461	COG1191	sigma factor activity
BF33_4610	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF33_4612	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF33_4614	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF33_4615	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF33_4616	COG1486	melibiose metabolic process
BF33_462	COG1873	PFAM PRC-barrel domain
BF33_4620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF33_4620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF33_4621	COG0726	polysaccharide deacetylase
BF33_4622	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF33_4623	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF33_4624	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF33_4625	COG1316	TRANSCRIPTIONal
BF33_4626	COG1739	Uncharacterized protein family UPF0029
BF33_4627	COG1307	EDD domain protein, DegV family
BF33_4628	COG1733	regulation of RNA biosynthetic process
BF33_4629	COG1388	LysM domain
BF33_4629	COG0791	NLP P60 protein
BF33_4630	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF33_4631	COG1040	competence protein
BF33_4632	COG1278	Cold shock
BF33_4633	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF33_4635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF33_4637	COG2884	Cell division ATP-binding protein ftsE
BF33_4638	COG2177	Part of the ABC transporter FtsEX involved in
BF33_4639	COG3409	Peptidoglycan-binding domain 1 protein
BF33_4639	COG0793	Belongs to the peptidase S41A family
BF33_464	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF33_4640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF33_4641	COG1132	(ABC) transporter
BF33_4644	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF33_4646	COG0583	DNA-binding transcription factor activity
BF33_4647	COG2855	membrane
BF33_4653	COG0789	Transcriptional regulator
BF33_4656	COG0556	nucleotide-excision repair
BF33_4657	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF33_4659	COG1950	PFAM Membrane protein of
BF33_466	COG0762	integral membrane protein
BF33_4663	COG0110	maltose O-acetyltransferase activity
BF33_4664	COG0457	Tetratricopeptide repeat
BF33_4665	COG0492	ferredoxin-NADP+ reductase activity
BF33_4667	COG1051	belongs to the nudix hydrolase family
BF33_4669	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF33_467	COG2302	S4 RNA-binding domain
BF33_4671	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF33_4673	COG2323	membrane
BF33_4676	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_468	COG3599	regulation of cell shape
BF33_4681	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF33_4684	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF33_4691	COG1346	cytolysis
BF33_4692	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF33_4693	COG1647	Serine aminopeptidase, S33
BF33_4694	COG0557	exoribonuclease II activity
BF33_4704	COG3223	Belongs to the PsiE family
BF33_4705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_4711	COG3290	protein histidine kinase activity
BF33_4711	COG0840	transmembrane signaling receptor activity
BF33_4715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF33_4716	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF33_4717	COG1252	NADH dehydrogenase
BF33_4719	COG1733	regulation of RNA biosynthetic process
BF33_472	COG0564	pseudouridine synthase activity
BF33_4720	COG2814	Major facilitator Superfamily
BF33_4721	COG0656	L-ascorbic acid biosynthetic process
BF33_4725	COG2910	NAD(P)H-binding
BF33_4726	COG1115	amino acid carrier protein
BF33_4727	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_4728	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF33_4732	COG1611	Belongs to the LOG family
BF33_4735	COG0783	Belongs to the Dps family
BF33_4736	COG1115	amino acid carrier protein
BF33_4737	COG0490	domain, Protein
BF33_4738	COG0475	glutathione-regulated potassium exporter activity
BF33_4741	COG1741	Belongs to the pirin family
BF33_4742	COG3227	Zinc metalloprotease (Elastase)
BF33_4743	COG2151	metal-sulfur cluster biosynthetic enzyme
BF33_4744	COG0840	transmembrane signaling receptor activity
BF33_4749	COG5002	protein histidine kinase activity
BF33_4750	COG0745	RESPONSE REGULATOR receiver
BF33_4751	COG1376	ErfK ybiS ycfS ynhG family protein
BF33_4753	COG0586	Pfam SNARE associated Golgi protein
BF33_4761	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_4763	COG0706	membrane insertase activity
BF33_4765	COG0531	amino acid
BF33_4766	COG2814	Major facilitator Superfamily
BF33_477	COG0505	Belongs to the CarA family
BF33_4770	COG0840	transmembrane signaling receptor activity
BF33_4771	COG0011	TIGRFAM Protein of
BF33_4774	COG1686	Belongs to the peptidase S11 family
BF33_4776	COG1024	Enoyl-CoA hydratase
BF33_4776	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF33_4777	COG0183	Belongs to the thiolase family
BF33_4778	COG1960	acyl-CoA dehydrogenase activity
BF33_4779	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_4780	COG1309	transcriptional regulator
BF33_4787	COG0039	L-malate dehydrogenase activity
BF33_4795	COG1393	Belongs to the ArsC family
BF33_4797	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF33_4798	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_4801	COG2011	ABC-type metal ion transport system permease component
BF33_4802	COG1464	Belongs to the NlpA lipoprotein family
BF33_4803	COG1464	Belongs to the NlpA lipoprotein family
BF33_4804	COG0396	ATPase activity
BF33_4805	COG0719	Fe-S assembly protein
BF33_4806	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF33_4807	COG0822	iron-sulfur transferase activity
BF33_4808	COG0719	Fe-S assembly protein
BF33_4809	COG0737	Belongs to the 5'-nucleotidase family
BF33_4810	COG3377	Domain of unknown function (DUF1805)
BF33_4812	COG0739	heme binding
BF33_4817	COG4377	Putative membrane peptidase family (DUF2324)
BF33_4818	COG0789	Transcriptional regulator
BF33_4820	COG4470	Protein conserved in bacteria
BF33_4823	COG1494	fructose-1,6-bisphosphatase
BF33_4824	COG2445	Protein of unknown function DUF86
BF33_4826	COG0647	UMP catabolic process
BF33_4828	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF33_4830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF33_4831	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF33_4833	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF33_4834	COG4837	Protein of unknown function (DUF1462)
BF33_4838	COG2824	Alkylphosphonate utilization operon protein PhnA
BF33_4839	COG0390	transport system, permease component
BF33_4840	COG2274	protein secretion by the type I secretion system
BF33_4841	COG1252	NADH dehydrogenase
BF33_4844	COG0316	Belongs to the HesB IscA family
BF33_4846	COG1683	Conserved Protein
BF33_4849	COG3708	Transcriptional regulator
BF33_485	COG3069	C4-dicarboxylate transmembrane transporter activity
BF33_4852	COG1252	NADH dehydrogenase
BF33_4855	COG3584	3D domain protein
BF33_4858	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF33_4859	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF33_4860	COG1268	BioY protein
BF33_4862	COG2050	protein possibly involved in aromatic compounds catabolism
BF33_4863	COG0423	glycine-tRNA ligase activity
BF33_4866	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF33_4867	COG5018	Exonuclease
BF33_4871	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF33_4873	COG2267	carboxylic ester hydrolase activity
BF33_4874	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF33_4875	COG1522	sequence-specific DNA binding
BF33_4876	COG0436	Aminotransferase
BF33_4877	COG1098	S1 RNA binding domain
BF33_4878	COG2155	Conserved Protein
BF33_488	COG0006	proline dipeptidase activity
BF33_4880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF33_4882	COG1285	pathogenesis
BF33_4890	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF33_49	COG0517	IMP dehydrogenase activity
BF33_490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF33_4909	COG1595	DNA-templated transcription, initiation
BF33_491	COG1561	YicC-like family, N-terminal region
BF33_4911	COG0039	L-malate dehydrogenase activity
BF33_4914	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF33_4915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF33_4917	COG0058	SHG alpha-glucan phosphorylase activity
BF33_4921	COG1278	Cold shock
BF33_4922	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF33_4923	COG1575	Belongs to the MenA family. Type 1 subfamily
BF33_4924	COG1169	isochorismate synthase
BF33_4926	COG0596	Alpha beta hydrolase
BF33_4927	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF33_4929	COG4948	Mandelate Racemase Muconate Lactonizing
BF33_493	COG0194	GDP metabolic process
BF33_4935	COG3964	amidohydrolase
BF33_4943	COG0577	efflux transmembrane transporter activity
BF33_4944	COG1136	(ABC) transporter
BF33_4945	COG0577	efflux transmembrane transporter activity
BF33_4946	COG0577	efflux transmembrane transporter activity
BF33_4947	COG2205	protein histidine kinase activity
BF33_4948	COG0745	RESPONSE REGULATOR receiver
BF33_4949	COG2207	Transcriptional regulator
BF33_4949	COG3708	Transcriptional regulator
BF33_495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF33_4950	COG1136	(ABC) transporter
BF33_4951	COG0577	efflux transmembrane transporter activity
BF33_4953	COG0586	Pfam SNARE associated Golgi protein
BF33_4958	COG1597	lipid kinase activity
BF33_496	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF33_4964	COG0745	RESPONSE REGULATOR receiver
BF33_4965	COG5002	protein histidine kinase activity
BF33_497	COG0242	peptide deformylase activity
BF33_4973	COG1842	Phage shock protein A
BF33_4978	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_4982	COG1294	oxidase, subunit
BF33_4983	COG1271	oxidase subunit
BF33_4985	COG0288	reversible hydration of carbon dioxide
BF33_499	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF33_499	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF33_4991	COG0494	nUDIX hydrolase
BF33_4993	COG0546	phosphoglycolate phosphatase activity
BF33_4996	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF33_4997	COG1116	anion transmembrane transporter activity
BF33_4998	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF33_5	COG1595	DNA-templated transcription, initiation
BF33_5001	COG1368	sulfuric ester hydrolase activity
BF33_5002	COG2267	carboxylic ester hydrolase activity
BF33_5003	COG4191	Histidine kinase
BF33_5004	COG5002	protein histidine kinase activity
BF33_5005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF33_501	COG0631	protein serine/threonine phosphatase activity
BF33_5015	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF33_5017	COG0438	transferase activity, transferring glycosyl groups
BF33_5018	COG0671	phosphoesterase, PA-phosphatase related
BF33_5019	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF33_502	COG2815	serine threonine protein kinase
BF33_502	COG0515	serine threonine protein kinase
BF33_5020	COG2267	carboxylic ester hydrolase activity
BF33_5024	COG1794	racemase activity, acting on amino acids and derivatives
BF33_5027	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF33_5028	COG1242	4 iron, 4 sulfur cluster binding
BF33_503	COG1162	GTPase activity
BF33_5032	COG1136	(ABC) transporter
BF33_5034	COG0582	viral genome integration into host DNA
BF33_5035	COG0490	domain, Protein
BF33_5036	COG0475	glutathione-regulated potassium exporter activity
BF33_5037	COG2814	Major facilitator Superfamily
BF33_504	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF33_5045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF33_5047	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF33_505	COG1564	THIamine pyrophosphokinase
BF33_5051	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF33_5052	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF33_5054	COG0303	'Molybdopterin
BF33_5055	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF33_5056	COG0314	molybdopterin synthase activity
BF33_5061	COG1329	Transcriptional regulator
BF33_5065	COG3832	glyoxalase III activity
BF33_5067	COG2814	Major facilitator Superfamily
BF33_5068	COG2081	HI0933 family
BF33_5069	COG2244	polysaccharide biosynthetic process
BF33_507	COG1302	Protein conserved in bacteria
BF33_5070	COG1187	pseudouridine synthase activity
BF33_5071	COG1349	DNA-binding transcription factor activity
BF33_5072	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF33_5074	COG1523	belongs to the glycosyl hydrolase 13 family
BF33_5075	COG0510	thiamine kinase activity
BF33_5078	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_508	COG1461	Dihydroxyacetone kinase
BF33_5080	COG1363	Peptidase, m42
BF33_5081	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF33_5082	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_5084	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF33_5086	COG1674	ftsk spoiiie
BF33_5089	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF33_509	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF33_5093	COG2309	aminopeptidase activity
BF33_5095	COG3118	belongs to the thioredoxin family
BF33_5096	COG4851	CamS sex pheromone cAM373 precursor
BF33_5097	COG1609	Transcriptional regulator
BF33_51	COG0358	DNA primase activity
BF33_5104	COG0666	response to abiotic stimulus
BF33_5105	COG5002	protein histidine kinase activity
BF33_5106	COG0745	RESPONSE REGULATOR receiver
BF33_5108	COG2267	carboxylic ester hydrolase activity
BF33_5109	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF33_5110	COG0517	IMP dehydrogenase activity
BF33_5111	COG0454	-acetyltransferase
BF33_5112	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF33_5114	COG1595	DNA-templated transcription, initiation
BF33_5116	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF33_512	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF33_5120	COG0626	cystathionine gamma-synthase activity
BF33_5121	COG1956	GAF domain-containing protein
BF33_5122	COG1309	transcriptional regulator
BF33_5123	COG0697	spore germination
BF33_5124	COG0583	DNA-binding transcription factor activity
BF33_5126	COG1104	cysteine desulfurase activity
BF33_5129	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF33_513	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_5131	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF33_5132	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF33_5134	COG3874	Sporulation protein YtfJ
BF33_5135	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF33_5136	COG0827	DNA restriction-modification system
BF33_5141	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_5150	COG0589	response to stress
BF33_5151	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_5154	COG1476	TRANSCRIPTIONal
BF33_5156	COG0662	Cupin 2, conserved barrel domain protein
BF33_516	COG1196	nuclear chromosome segregation
BF33_5165	COG0006	proline dipeptidase activity
BF33_5168	COG4109	DRTGG domain
BF33_517	COG0552	protein localization to endoplasmic reticulum
BF33_5172	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF33_5175	COG0587	DNA-directed DNA polymerase activity
BF33_5176	COG0281	malic enzyme
BF33_5177	COG1725	Transcriptional regulator
BF33_5182	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF33_5183	COG0628	permease
BF33_5185	COG0372	Belongs to the citrate synthase family
BF33_5186	COG0538	isocitrate dehydrogenase activity
BF33_519	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF33_5191	COG0745	RESPONSE REGULATOR receiver
BF33_5192	COG5002	protein histidine kinase activity
BF33_5193	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF33_5193	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF33_5194	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF33_5195	COG1971	Probably functions as a manganese efflux pump
BF33_5196	COG0237	dephospho-CoA kinase activity
BF33_5197	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF33_5198	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF33_52	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF33_5200	COG3611	Membrane attachment protein
BF33_5201	COG1484	DNA-dependent DNA replication
BF33_5203	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF33_5204	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF33_5208	COG1363	Peptidase, m42
BF33_5209	COG1309	transcriptional regulator
BF33_521	COG1837	Belongs to the UPF0109 family
BF33_5210	COG1566	PFAM secretion protein HlyD family protein
BF33_5211	COG2814	Major facilitator Superfamily
BF33_5216	COG1418	mRNA catabolic process
BF33_5218	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF33_5220	COG0072	phenylalanine-tRNA ligase activity
BF33_5220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF33_5221	COG0017	Asparaginyl-tRNA synthetase
BF33_5227	COG1286	toxin biosynthetic process
BF33_5228	COG1796	DNA polymerase
BF33_5228	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF33_5231	COG1187	pseudouridine synthase activity
BF33_5232	COG1114	Component of the transport system for branched-chain amino acids
BF33_5233	COG5386	Cell surface protein
BF33_5235	COG5386	Cell surface protein
BF33_5238	COG1120	ATPase activity
BF33_5239	COG4509	Sortase family
BF33_5242	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF33_5243	COG4895	conserved protein (DUF2196)
BF33_5245	COG0745	RESPONSE REGULATOR receiver
BF33_5246	COG2205	protein histidine kinase activity
BF33_5247	COG1131	(ABC) transporter
BF33_5252	COG2318	DinB family
BF33_5256	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_5257	COG1309	transcriptional regulator
BF33_5258	COG1024	Enoyl-CoA hydratase
BF33_5259	COG2086	electron transfer activity
BF33_5260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF33_5261	COG3118	belongs to the thioredoxin family
BF33_5263	COG1719	4-vinyl reductase, 4VR
BF33_5264	COG2009	succinate dehydrogenase
BF33_5265	COG1053	succinate dehydrogenase
BF33_5266	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF33_5267	COG0824	Thioesterase
BF33_5268	COG1876	peptidase activity
BF33_5269	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF33_5270	COG1360	Flagellar Motor Protein
BF33_5271	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF33_5272	COG4152	abc transporter atp-binding protein
BF33_5273	COG1668	transmembrane transport
BF33_5274	COG1959	2 iron, 2 sulfur cluster binding
BF33_5276	COG0697	spore germination
BF33_5277	COG1396	sequence-specific DNA binding
BF33_5278	COG1983	PspC domain protein
BF33_5280	COG3279	Response regulator of the LytR AlgR family
BF33_5281	COG3275	phosphorelay sensor kinase activity
BF33_5282	COG4608	Belongs to the ABC transporter superfamily
BF33_5283	COG0444	Belongs to the ABC transporter superfamily
BF33_5287	COG0402	S-adenosylhomocysteine deaminase activity
BF33_5288	COG0402	S-adenosylhomocysteine deaminase activity
BF33_529	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF33_5290	COG2233	PERMEase
BF33_5291	COG2197	response regulator
BF33_5296	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF33_5296	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF33_53	COG2010	Cytochrome c
BF33_530	COG0758	DNA mediated transformation
BF33_5301	COG0798	PFAM Bile acid sodium symporter
BF33_5304	COG0640	Transcriptional regulator
BF33_5309	COG1595	DNA-templated transcription, initiation
BF33_531	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF33_5310	COG2226	methyltransferase
BF33_5319	COG1309	transcriptional regulator
BF33_5323	COG5401	PFAM Sporulation and spore germination
BF33_5325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF33_5326	COG0622	Phosphoesterase
BF33_533	COG4974	Belongs to the 'phage' integrase family
BF33_5337	COG0470	DNA polymerase III
BF33_5337	COG1067	ATP-dependent peptidase activity
BF33_5340	COG1764	response to oxidative stress
BF33_5341	COG1846	Transcriptional regulator
BF33_5343	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF33_5345	COG1587	Uroporphyrinogen-III synthase
BF33_5346	COG0113	porphobilinogen synthase activity
BF33_5348	COG1388	LysM domain
BF33_5351	COG0285	dihydrofolate synthase activity
BF33_5355	COG1077	Cell shape determining protein MreB Mrl
BF33_5356	COG1792	Involved in formation and maintenance of cell shape
BF33_5359	COG2894	cell division
BF33_5360	COG0739	heme binding
BF33_5361	COG1994	Peptidase M50
BF33_5362	COG1530	ribonuclease E activity
BF33_5364	COG2868	ribosomal protein
BF33_5366	COG3290	protein histidine kinase activity
BF33_5368	COG0745	RESPONSE REGULATOR receiver
BF33_5369	COG5002	protein histidine kinase activity
BF33_5370	COG1136	(ABC) transporter
BF33_5371	COG0577	efflux transmembrane transporter activity
BF33_5372	COG0577	efflux transmembrane transporter activity
BF33_5373	COG0077	Prephenate dehydratase
BF33_5374	COG2258	MOSC domain
BF33_5375	COG1827	regulation of RNA biosynthetic process
BF33_5376	COG1104	cysteine desulfurase activity
BF33_5377	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF33_5378	COG0157	Belongs to the NadC ModD family
BF33_5384	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF33_539	COG0528	UMP kinase activity
BF33_5390	COG1862	Preprotein translocase
BF33_5392	COG2323	membrane
BF33_5393	COG2244	polysaccharide biosynthetic process
BF33_5395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF33_5395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF33_5396	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF33_5397	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF33_5397	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF33_5399	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF33_54	COG2384	SAM-dependent methyltransferase
BF33_5403	COG0124	histidyl-tRNA synthetase
BF33_5405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF33_5407	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF33_5408	COG1959	2 iron, 2 sulfur cluster binding
BF33_5409	COG1104	cysteine desulfurase activity
BF33_5412	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF33_5416	COG0628	permease
BF33_542	COG4589	Belongs to the CDS family
BF33_5422	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF33_5428	COG0768	penicillin binding
BF33_543	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF33_5433	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF33_5434	COG0626	cystathionine gamma-synthase activity
BF33_5435	COG1012	belongs to the aldehyde dehydrogenase family
BF33_5435	COG1454	alcohol dehydrogenase
BF33_5437	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_544	COG0750	zinc metalloprotease
BF33_5445	COG2259	Doxx family
BF33_5446	COG2514	catechol 2,3-dioxygenase activity
BF33_5448	COG3186	Phenylalanine-4-hydroxylase
BF33_5449	COG1404	Belongs to the peptidase S8 family
BF33_5456	COG2267	carboxylic ester hydrolase activity
BF33_5458	COG1785	Belongs to the alkaline phosphatase family
BF33_5463	COG2323	membrane
BF33_5466	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF33_5470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BF33_5473	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_548	COG0195	Participates in both transcription termination and antitermination
BF33_5481	COG3708	Transcriptional regulator
BF33_5481	COG2207	Transcriptional regulator
BF33_5486	COG1335	isochorismatase
BF33_549	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF33_5494	COG0546	phosphoglycolate phosphatase activity
BF33_55	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF33_550	COG1358	cellular component organization or biogenesis
BF33_5503	COG3344	reverse transcriptase
BF33_5507	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_5517	COG1780	Probably involved in ribonucleotide reductase function
BF33_552	COG1550	Protein conserved in bacteria
BF33_554	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF33_5545	COG0681	Belongs to the peptidase S26 family
BF33_555	COG0196	riboflavin kinase activity
BF33_5550	COG1466	dna polymerase III delta subunit
BF33_5552	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF33_5555	COG3344	reverse transcriptase
BF33_558	COG0726	polysaccharide deacetylase
BF33_5582	COG3344	reverse transcriptase
BF33_5586	COG0791	NLP P60 protein
BF33_5586	COG0741	lytic transglycosylase activity
BF33_559	COG0612	Peptidase, M16
BF33_5593	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF33_5598	COG2801	Transposase and inactivated derivatives
BF33_560	COG1873	PFAM PRC-barrel domain
BF33_5609	COG2318	DinB family
BF33_561	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF33_562	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF33_563	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF33_564	COG0527	aspartate kinase activity
BF33_5644	COG1674	ftsk spoiiie
BF33_5653	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF33_5655	COG0210	DNA helicase
BF33_5656	COG0470	DNA polymerase III
BF33_566	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF33_5660	COG2304	oxidoreductase activity
BF33_5661	COG2002	toxin-antitoxin pair type II binding
BF33_5666	COG2963	transposase activity
BF33_5667	COG2801	Transposase and inactivated derivatives
BF33_5668	COG1876	peptidase activity
BF33_567	COG0740	serine-type endopeptidase activity
BF33_5675	COG0798	PFAM Bile acid sodium symporter
BF33_5676	COG0640	Transcriptional regulator
BF33_5680	COG0523	cobalamin synthesis protein
BF33_5681	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF33_5683	COG3620	sequence-specific DNA binding
BF33_5684	COG0306	phosphate transporter
BF33_5685	COG0640	Transcriptional regulator
BF33_5688	COG1846	Transcriptional regulator
BF33_569	COG1674	ftsk spoiiie
BF33_5698	COG2217	Heavy metal translocating P-type atpase
BF33_5699	COG1937	Protein conserved in bacteria
BF33_570	COG2188	Transcriptional regulator
BF33_5700	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF33_5700	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF33_5704	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_5724	COG3118	belongs to the thioredoxin family
BF33_5728	COG1126	abc transporter atp-binding protein
BF33_5729	COG2304	oxidoreductase activity
BF33_5730	COG2132	Multicopper oxidase
BF33_5731	COG0745	RESPONSE REGULATOR receiver
BF33_5732	COG5002	protein histidine kinase activity
BF33_5734	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF33_5744	COG2918	glutathione biosynthetic process
BF33_5744	COG1181	Belongs to the D-alanine--D-alanine ligase family
BF33_5746	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BF33_5748	COG1733	regulation of RNA biosynthetic process
BF33_575	COG0612	Peptidase, M16
BF33_5752	COG0697	spore germination
BF33_5756	COG0305	Participates in initiation and elongation during chromosome replication
BF33_576	COG0612	Peptidase, M16
BF33_577	COG0300	oxidoreductase activity
BF33_5776	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BF33_5783	COG5484	DNA packaging
BF33_5785	COG5518	Phage portal protein
BF33_5786	COG2369	cell adhesion
BF33_5787	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BF33_5788	COG4653	Phage capsid family
BF33_580	COG1426	Protein conserved in bacteria
BF33_5806	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF33_5809	COG0322	excinuclease ABC activity
BF33_581	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF33_5818	COG1192	Involved in chromosome partitioning
BF33_5826	COG1396	sequence-specific DNA binding
BF33_5832	COG5377	YqaJ viral recombinase family
BF33_5833	COG3723	Recombinational DNA repair protein, rece pathway
BF33_586	COG1692	metallophosphoesterase
BF33_587	COG2359	stage V sporulation protein S
BF33_589	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF33_589	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF33_590	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF33_592	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF33_596	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF33_598	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF33_599	COG1368	sulfuric ester hydrolase activity
BF33_600	COG0562	UDP-galactopyranose mutase
BF33_601	COG3773	Cell wall hydrolase
BF33_602	COG1404	Belongs to the peptidase S8 family
BF33_605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF33_606	COG0596	Alpha beta hydrolase
BF33_606	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF33_607	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF33_608	COG1380	Effector of murein hydrolase LrgA
BF33_609	COG1346	cytolysis
BF33_61	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_612	COG5001	Diguanylate cyclase
BF33_612	COG3300	MHYT domain
BF33_613	COG0346	lactoylglutathione lyase activity
BF33_614	COG2267	carboxylic ester hydrolase activity
BF33_617	COG2364	Membrane
BF33_619	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF33_62	COG1121	(ABC) transporter
BF33_620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF33_621	COG2169	Transcriptional regulator
BF33_622	COG0708	Exodeoxyribonuclease III
BF33_623	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_624	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_626	COG1120	ATPase activity
BF33_627	COG2819	hydrolase of the alpha beta superfamily
BF33_629	COG1937	Protein conserved in bacteria
BF33_63	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF33_630	COG2608	mercury ion transmembrane transporter activity
BF33_631	COG2217	Heavy metal translocating P-type atpase
BF33_633	COG2116	formate transmembrane transporter activity
BF33_634	COG1408	metallophosphoesterase
BF33_637	COG1113	amino acid transport
BF33_64	COG0735	belongs to the Fur family
BF33_640	COG2322	membrane
BF33_641	COG1979	alcohol dehydrogenase
BF33_642	COG1349	DNA-binding transcription factor activity
BF33_643	COG1105	Belongs to the carbohydrate kinase PfkB family
BF33_644	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF33_644	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF33_644	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF33_645	COG1388	LysM domain
BF33_645	COG3584	3D domain protein
BF33_651	COG0464	growth
BF33_653	COG2860	membrane
BF33_654	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF33_655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF33_656	COG0789	Transcriptional regulator
BF33_657	COG0174	glutamine synthetase
BF33_660	COG5444	nuclease activity
BF33_663	COG1695	Transcriptional regulator
BF33_667	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF33_669	COG0737	Belongs to the 5'-nucleotidase family
BF33_671	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF33_672	COG3639	organic phosphonate transmembrane transporter activity
BF33_678	COG1132	(ABC) transporter
BF33_679	COG1132	(ABC) transporter
BF33_682	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF33_682	COG3409	Peptidoglycan-binding domain 1 protein
BF33_684	COG0730	response to heat
BF33_687	COG1346	cytolysis
BF33_689	COG0583	DNA-binding transcription factor activity
BF33_69	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF33_691	COG1131	(ABC) transporter
BF33_695	COG0785	Cytochrome C biogenesis protein
BF33_696	COG4846	Membrane protein involved in cytochrome C biogenesis
BF33_7	COG1191	sigma factor activity
BF33_70	COG0477	Major facilitator Superfamily
BF33_702	COG2226	methyltransferase
BF33_708	COG0010	Belongs to the arginase family
BF33_709	COG1329	Transcriptional regulator
BF33_710	COG1902	pentaerythritol trinitrate reductase activity
BF33_711	COG0069	glutamate synthase activity
BF33_712	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF33_713	COG0346	lactoylglutathione lyase activity
BF33_714	COG0400	carboxylic ester hydrolase activity
BF33_715	COG5002	protein histidine kinase activity
BF33_717	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF33_72	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF33_727	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_728	COG1268	BioY protein
BF33_729	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_73	COG0573	inorganic phosphate transmembrane transporter activity
BF33_730	COG0183	Belongs to the thiolase family
BF33_733	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF33_735	COG2211	Major facilitator Superfamily
BF33_739	COG0726	polysaccharide deacetylase
BF33_74	COG0581	inorganic phosphate transmembrane transporter activity
BF33_741	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF33_742	COG2274	protein secretion by the type I secretion system
BF33_744	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF33_745	COG2176	DNA-directed DNA polymerase activity
BF33_75	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF33_750	COG0824	Thioesterase
BF33_751	COG4841	protein insertion into membrane
BF33_755	COG0745	RESPONSE REGULATOR receiver
BF33_756	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF33_757	COG1832	CoA-binding protein
BF33_758	COG0187	DNA topoisomerase II activity
BF33_759	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF33_76	COG0704	Plays a role in the regulation of phosphate uptake
BF33_760	COG0673	inositol 2-dehydrogenase activity
BF33_762	COG1131	(ABC) transporter
BF33_766	COG1595	DNA-templated transcription, initiation
BF33_768	COG1316	TRANSCRIPTIONal
BF33_769	COG1301	dicarboxylic acid transport
BF33_77	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF33_770	COG4166	transmembrane transport
BF33_771	COG4166	transmembrane transport
BF33_772	COG2801	Transposase and inactivated derivatives
BF33_775	COG4166	transmembrane transport
BF33_776	COG2226	methyltransferase
BF33_784	COG0697	spore germination
BF33_786	COG3383	formate dehydrogenase (NAD+) activity
BF33_787	COG2427	Protein of unknown function (DUF1641)
BF33_788	COG5609	conserved protein (DUF2294)
BF33_789	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF33_79	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF33_791	COG2116	formate transmembrane transporter activity
BF33_792	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF33_793	COG0303	'Molybdopterin
BF33_794	COG0314	molybdopterin synthase activity
BF33_796	COG0489	protein tyrosine kinase activity
BF33_799	COG2962	Rard protein
BF33_80	COG4483	Protein conserved in bacteria
BF33_800	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF33_801	COG1657	PFAM Prenyltransferase squalene oxidase
BF33_802	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_803	COG1012	belongs to the aldehyde dehydrogenase family
BF33_805	COG4145	pantothenate transmembrane transporter activity
BF33_808	COG0165	Argininosuccinate lyase
BF33_81	COG1940	carbohydrate kinase activity
BF33_810	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_814	COG1051	belongs to the nudix hydrolase family
BF33_816	COG0716	FMN binding
BF33_818	COG1278	Cold shock
BF33_824	COG2720	vancomycin resistance protein
BF33_825	COG2514	catechol 2,3-dioxygenase activity
BF33_828	COG1285	pathogenesis
BF33_83	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_830	COG1024	Enoyl-CoA hydratase
BF33_831	COG1216	Glycosyl transferase, family 2
BF33_839	COG0385	Bile acid
BF33_841	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF33_842	COG2808	Putative FMN-binding domain
BF33_844	COG0457	Tetratricopeptide repeat
BF33_846	COG0604	alcohol dehydrogenase
BF33_847	COG0640	Transcriptional regulator
BF33_851	COG0584	glycerophosphoryl diester phosphodiesterase
BF33_857	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF33_858	COG1164	Oligoendopeptidase f
BF33_859	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF33_862	COG1193	negative regulation of DNA recombination
BF33_866	COG0583	DNA-binding transcription factor activity
BF33_87	COG0626	cystathionine gamma-synthase activity
BF33_873	COG0384	phenazine biosynthesis protein PhzF
BF33_874	COG3739	integral membrane protein
BF33_875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_876	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF33_877	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF33_88	COG0626	cystathionine gamma-synthase activity
BF33_880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF33_881	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF33_887	COG2814	Major facilitator Superfamily
BF33_888	COG1113	amino acid transport
BF33_889	COG0604	alcohol dehydrogenase
BF33_89	COG0646	methionine synthase
BF33_89	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF33_896	COG2072	flavoprotein involved in K transport
BF33_90	COG1410	methionine synthase
BF33_90	COG0646	methionine synthase
BF33_904	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_907	COG1151	hydroxylamine reductase activity
BF33_91	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF33_912	COG3152	Membrane
BF33_916	COG1309	transcriptional regulator
BF33_919	COG1191	sigma factor activity
BF33_921	COG0726	polysaccharide deacetylase
BF33_923	COG1733	regulation of RNA biosynthetic process
BF33_924	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF33_925	COG0318	PFAM AMP-dependent synthetase and ligase
BF33_930	COG0384	phenazine biosynthesis protein PhzF
BF33_934	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF33_937	COG1733	regulation of RNA biosynthetic process
BF33_938	COG1733	regulation of RNA biosynthetic process
BF33_939	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF33_940	COG0673	inositol 2-dehydrogenase activity
BF33_941	COG2188	Transcriptional regulator
BF33_942	COG1393	Belongs to the ArsC family
BF33_948	COG0814	amino acid
BF33_951	COG0656	L-ascorbic acid biosynthetic process
BF33_956	COG1028	Short-chain dehydrogenase reductase Sdr
BF33_959	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF33_961	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF33_963	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF33_964	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF33_966	COG1070	Carbohydrate kinase
BF33_967	COG2706	6-phosphogluconolactonase activity
BF33_968	COG3813	Protein conserved in bacteria
BF33_969	COG1357	PFAM Pentapeptide repeats (8 copies)
BF33_970	COG0697	spore germination
BF33_971	COG0789	Transcriptional regulator
BF33_972	COG1253	flavin adenine dinucleotide binding
BF33_978	COG0477	Major facilitator Superfamily
BF33_980	COG2226	methyltransferase
BF33_984	COG0628	permease
BF33_986	COG0180	Tryptophanyl-tRNA synthetase
BF33_988	COG0577	efflux transmembrane transporter activity
BF33_988	COG1136	(ABC) transporter
BF33_990	COG0110	maltose O-acetyltransferase activity
BF33_991	COG0738	Major facilitator superfamily
BF33_992	COG1940	carbohydrate kinase activity
BF33_993	COG0346	lactoylglutathione lyase activity