locus-tag	class	description
GE376_00010	COG0592	DNA-directed DNA polymerase activity
GE376_00015	COG2501	S4 domain
GE376_00025	COG0187	DNA topoisomerase II activity
GE376_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE376_00065	COG0517	IMP dehydrogenase activity
GE376_00065	COG0516	GMP reductase activity
GE376_00070	COG1686	Belongs to the peptidase S11 family
GE376_00100	COG1428	Deoxynucleoside kinase
GE376_00105	COG1428	Deoxynucleoside kinase
GE376_00110	COG1335	isochorismatase
GE376_00115	COG0590	tRNA wobble adenosine to inosine editing
GE376_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GE376_00180	COG1982	Orn Lys Arg decarboxylase major
GE376_00190	COG0470	DNA polymerase III
GE376_00195	COG1774	PSP1 C-terminal conserved region
GE376_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GE376_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GE376_00220	COG2002	toxin-antitoxin pair type II binding
GE376_00230	COG0084	hydrolase, TatD family'
GE376_00250	COG4466	Protein conserved in bacteria
GE376_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE376_00270	COG0251	oxidation-reduction process
GE376_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GE376_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GE376_00305	COG2002	toxin-antitoxin pair type II binding
GE376_00310	COG2244	polysaccharide biosynthetic process
GE376_00315	COG3956	TIGRFAM MazG family protein
GE376_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GE376_00340	COG1098	S1 RNA binding domain
GE376_00355	COG2208	phosphoserine phosphatase activity
GE376_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE376_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GE376_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GE376_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GE376_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GE376_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GE376_00420	COG1396	sequence-specific DNA binding
GE376_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE376_00515	COG3880	PFAM UvrB UvrC protein
GE376_00525	COG0542	response to heat
GE376_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GE376_00540	COG4956	integral membrane protein (PIN domain superfamily)
GE376_00560	COG1045	serine acetyltransferase
GE376_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE376_00580	COG3688	RNA-binding protein containing a PIN domain
GE376_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GE376_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE376_00600	COG0250	Participates in transcription elongation, termination and antitermination
GE376_00625	COG2813	Specifically methylates the guanine in position
GE376_00640	COG1358	cellular component organization or biogenesis
GE376_00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GE376_00775	COG0201	protein transport
GE376_00785	COG0024	Methionine aminopeptidase
GE376_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GE376_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GE376_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_00860	COG0489	protein tyrosine kinase activity
GE376_00870	COG2194	sulfuric ester hydrolase activity
GE376_00875	COG0726	polysaccharide deacetylase
GE376_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GE376_00960	COG4856	YbbR-like protein
GE376_01000	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_01005	COG2011	ABC-type metal ion transport system permease component
GE376_01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GE376_01015	COG1464	Belongs to the NlpA lipoprotein family
GE376_01020	COG0604	alcohol dehydrogenase
GE376_01030	COG0277	FAD linked oxidase domain protein
GE376_01035	COG2271	Major facilitator Superfamily
GE376_01045	COG2814	Major facilitator Superfamily
GE376_01065	COG0601	transmembrane transport
GE376_01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_01075	COG0444	Belongs to the ABC transporter superfamily
GE376_01080	COG4608	Belongs to the ABC transporter superfamily
GE376_01085	COG4166	transmembrane transport
GE376_01100	COG4166	transmembrane transport
GE376_01105	COG4166	transmembrane transport
GE376_01110	COG0656	L-ascorbic acid biosynthetic process
GE376_01130	COG4149	molybdate abc transporter
GE376_01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
GE376_01140	COG1910	domain protein
GE376_01155	COG0697	spore germination
GE376_01170	COG0204	Acyl-transferase
GE376_01180	COG1609	Transcriptional regulator
GE376_01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_01205	COG5298	Protein conserved in bacteria
GE376_01230	COG0488	(ABC) transporter
GE376_01245	COG0747	negative chemotaxis
GE376_01250	COG0601	transmembrane transport
GE376_01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_01260	COG0444	Belongs to the ABC transporter superfamily
GE376_01265	COG4608	Belongs to the ABC transporter superfamily
GE376_01270	COG0561	phosphatase activity
GE376_01295	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GE376_01300	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE376_01310	COG0531	amino acid
GE376_01315	COG2814	Major facilitator Superfamily
GE376_01325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE376_01335	COG4294	response to UV
GE376_01340	COG0705	Rhomboid family
GE376_01350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GE376_01355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GE376_01360	COG0864	Transcriptional regulator
GE376_01365	COG2337	Toxic component of a toxin-antitoxin (TA) module
GE376_01370	COG2183	response to ionizing radiation
GE376_01470	COG0802	atpase or kinase
GE376_01475	COG1214	PFAM Peptidase M22, glycoprotease
GE376_01480	COG0456	acetyltransferase
GE376_01490	COG0488	(ABC) transporter
GE376_01505	COG1266	CAAX protease self-immunity
GE376_01525	COG2252	PERMEase
GE376_01535	COG5002	protein histidine kinase activity
GE376_01560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GE376_01585	COG0506	proline dehydrogenase activity
GE376_01625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_01635	COG1215	transferase activity, transferring glycosyl groups
GE376_01655	COG0697	spore germination
GE376_01685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GE376_01690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GE376_01695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GE376_01705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE376_01720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GE376_01730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GE376_01740	COG0151	Belongs to the GarS family
GE376_01750	COG0583	DNA-binding transcription factor activity
GE376_01775	COG0210	DNA helicase
GE376_01785	COG4851	CamS sex pheromone cAM373 precursor
GE376_01800	COG1335	isochorismatase
GE376_01815	COG2011	ABC-type metal ion transport system permease component
GE376_01820	COG1464	Belongs to the NlpA lipoprotein family
GE376_01835	COG0003	Pfam Anion-transporting ATPase
GE376_01840	COG1846	Transcriptional regulator
GE376_01845	COG4682	membrane
GE376_01865	COG1597	lipid kinase activity
GE376_01875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GE376_01885	COG1012	belongs to the aldehyde dehydrogenase family
GE376_01890	COG2076	Multidrug Resistance protein
GE376_01900	COG2309	aminopeptidase activity
GE376_01915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_01925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE376_01940	COG4807	Protein conserved in bacteria
GE376_01975	COG1473	amidohydrolase
GE376_01990	COG0450	alkyl hydroperoxide reductase
GE376_01995	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GE376_02005	COG0235	Class ii aldolase
GE376_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_02020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_02045	COG0166	Belongs to the GPI family
GE376_02070	COG5002	protein histidine kinase activity
GE376_02090	COG3541	Predicted nucleotidyltransferase
GE376_02095	COG2814	Major facilitator Superfamily
GE376_02100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_02100	COG0723	plastoquinol--plastocyanin reductase activity
GE376_02110	COG0765	amino acid transport
GE376_02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_02125	COG0840	transmembrane signaling receptor activity
GE376_02150	COG0549	Belongs to the carbamate kinase family
GE376_02155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_02165	COG0277	FAD linked oxidase domain protein
GE376_02170	COG0366	Alpha amylase catalytic
GE376_02175	COG1263	PTS System
GE376_02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_02175	COG2190	(PTS) system
GE376_02205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GE376_02225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_02230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_02235	COG1116	anion transmembrane transporter activity
GE376_02240	COG0488	(ABC) transporter
GE376_02290	COG2270	Major facilitator Superfamily
GE376_02320	COG2310	stress, protein
GE376_02325	COG2310	stress, protein
GE376_02330	COG2310	stress, protein
GE376_02335	COG0861	Integral membrane protein TerC family
GE376_02345	COG3853	Toxic anion resistance protein (TelA)
GE376_02360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE376_02370	COG1295	ribonuclease BN
GE376_02375	COG2217	Heavy metal translocating P-type atpase
GE376_02380	COG0697	spore germination
GE376_02400	COG0586	Pfam SNARE associated Golgi protein
GE376_02415	COG3871	stress protein (general stress protein 26)
GE376_02420	COG0387	Pfam Sodium calcium exchanger
GE376_02430	COG0535	radical SAM domain protein
GE376_02450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GE376_02455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GE376_02470	COG3829	transcription factor binding
GE376_02480	COG0833	amino acid
GE376_02485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_02515	COG1263	PTS System
GE376_02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_02520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_02535	COG1216	Glycosyl transferase, family 2
GE376_02545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GE376_02545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_02550	COG0463	Glycosyl transferase, family 2
GE376_02565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE376_02585	COG1228	amidohydrolase
GE376_02590	COG1090	epimerase
GE376_02620	COG1988	membrane-bound metal-dependent
GE376_02625	COG1194	a g-specific adenine glycosylase
GE376_02655	COG1132	(ABC) transporter
GE376_02660	COG4129	membrane
GE376_02665	COG0067	glutamate synthase
GE376_02665	COG0069	glutamate synthase activity
GE376_02665	COG0070	glutamate synthase
GE376_02675	COG4555	ABC transporter
GE376_02695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GE376_02700	COG0735	belongs to the Fur family
GE376_02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GE376_02845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GE376_02850	COG1716	ATPase activity
GE376_02850	COG5001	Diguanylate cyclase
GE376_02855	COG2766	serine protein kinase
GE376_02875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_02885	COG1585	Membrane protein implicated in regulation of membrane protease activity
GE376_02890	COG2268	Band 7 protein
GE376_02900	COG3290	protein histidine kinase activity
GE376_02905	COG4565	transcriptional regulatory protein
GE376_02910	COG2851	Citrate transporter
GE376_02935	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GE376_02940	COG3842	ATPase activity
GE376_02945	COG1175	transmembrane transport
GE376_02950	COG0395	ABC-type sugar transport system, permease component
GE376_02960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GE376_02965	COG0745	RESPONSE REGULATOR receiver
GE376_02970	COG5002	protein histidine kinase activity
GE376_02980	COG4990	cell redox homeostasis
GE376_02990	COG3290	protein histidine kinase activity
GE376_02995	COG4565	transcriptional regulatory protein
GE376_03000	COG3493	citrate carrier protein
GE376_03005	COG0281	malic enzyme
GE376_03015	COG0697	spore germination
GE376_03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_03030	COG5002	protein histidine kinase activity
GE376_03035	COG0745	RESPONSE REGULATOR receiver
GE376_03040	COG0456	acetyltransferase
GE376_03040	COG0454	-acetyltransferase
GE376_03045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GE376_03050	COG3383	formate dehydrogenase (NAD+) activity
GE376_03055	COG2427	Protein of unknown function (DUF1641)
GE376_03070	COG0531	amino acid
GE376_03075	COG0640	Transcriptional regulator
GE376_03080	COG2217	Heavy metal translocating P-type atpase
GE376_03095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GE376_03110	COG3227	Zinc metalloprotease (Elastase)
GE376_03130	COG2720	vancomycin resistance protein
GE376_03135	COG1316	TRANSCRIPTIONal
GE376_03140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_03145	COG0346	lactoylglutathione lyase activity
GE376_03150	COG1253	flavin adenine dinucleotide binding
GE376_03155	COG1027	Aspartate ammonia-lyase
GE376_03160	COG1620	l-lactate permease
GE376_03180	COG3104	oligopeptide transport
GE376_03185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_03210	COG0156	8-amino-7-oxononanoate synthase activity
GE376_03215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_03225	COG4548	von Willebrand factor, type A
GE376_03230	COG0714	Associated with various cellular activities
GE376_03250	COG0531	amino acid
GE376_03255	COG2188	Transcriptional regulator
GE376_03260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_03260	COG1263	PTS System
GE376_03265	COG0366	Alpha amylase catalytic
GE376_03280	COG0697	spore germination
GE376_03290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GE376_03295	COG1115	amino acid carrier protein
GE376_03300	COG1126	abc transporter atp-binding protein
GE376_03305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_03310	COG0765	amino acid transport
GE376_03315	COG0765	amino acid transport
GE376_03320	COG0833	amino acid
GE376_03335	COG1595	DNA-templated transcription, initiation
GE376_03345	COG2378	regulation of single-species biofilm formation
GE376_03350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE376_03355	COG5002	protein histidine kinase activity
GE376_03370	COG0659	secondary active sulfate transmembrane transporter activity
GE376_03385	COG0747	negative chemotaxis
GE376_03395	COG0601	transmembrane transport
GE376_03400	COG4608	Belongs to the ABC transporter superfamily
GE376_03410	COG2271	Major facilitator Superfamily
GE376_03415	COG1846	Transcriptional regulator
GE376_03420	COG0477	Major facilitator Superfamily
GE376_03425	COG1609	Transcriptional regulator
GE376_03430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE376_03445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE376_03450	COG1879	ABC-type sugar transport system periplasmic component
GE376_03455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GE376_03475	COG1063	alcohol dehydrogenase
GE376_03525	COG0840	transmembrane signaling receptor activity
GE376_03530	COG3583	domain protein
GE376_03530	COG3584	3D domain protein
GE376_03535	COG1476	TRANSCRIPTIONal
GE376_03555	COG3104	oligopeptide transport
GE376_03560	COG1114	Component of the transport system for branched-chain amino acids
GE376_03575	COG1113	amino acid transport
GE376_03580	COG2252	PERMEase
GE376_03595	COG2153	protein acetylation
GE376_03605	COG0569	domain protein
GE376_03605	COG0475	glutathione-regulated potassium exporter activity
GE376_03615	COG1845	cytochrome c oxidase, subunit III
GE376_03620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GE376_03630	COG0833	amino acid
GE376_03635	COG4990	cell redox homeostasis
GE376_03650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_03655	COG0697	spore germination
GE376_03660	COG0531	amino acid
GE376_03670	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_03675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_03680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_03680	COG1918	ferrous iron import across plasma membrane
GE376_03685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GE376_03690	COG0573	inorganic phosphate transmembrane transporter activity
GE376_03695	COG0581	inorganic phosphate transmembrane transporter activity
GE376_03705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE376_03825	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GE376_03845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GE376_03850	COG1116	anion transmembrane transporter activity
GE376_03855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_03860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_03865	COG0352	thiamine-phosphate diphosphorylase activity
GE376_03870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_03875	COG2104	thiamine diphosphate biosynthetic process
GE376_03885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_03890	COG0351	phosphomethylpyrimidine kinase
GE376_03930	COG2205	protein histidine kinase activity
GE376_03935	COG2814	Major facilitator Superfamily
GE376_03940	COG1846	Transcriptional regulator
GE376_03955	COG2252	PERMEase
GE376_03960	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_04020	COG0778	Nitroreductase
GE376_04025	COG2719	SpoVR family
GE376_04035	COG1414	Transcriptional regulator
GE376_04050	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE376_04055	COG1937	Protein conserved in bacteria
GE376_04060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_04060	COG0425	Belongs to the sulfur carrier protein TusA family
GE376_04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_04065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_04070	COG0425	Belongs to the sulfur carrier protein TusA family
GE376_04075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_04085	COG2210	Belongs to the sulfur carrier protein TusA family
GE376_04090	COG0730	response to heat
GE376_04100	COG1316	TRANSCRIPTIONal
GE376_04105	COG0604	alcohol dehydrogenase
GE376_04110	COG1283	sodium-dependent phosphate transmembrane transporter activity
GE376_04130	COG3711	transcriptional antiterminator
GE376_04130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_04135	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_04140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_04160	COG3584	3D domain protein
GE376_04160	COG1388	LysM domain
GE376_04165	COG0577	efflux transmembrane transporter activity
GE376_04170	COG1136	(ABC) transporter
GE376_04180	COG5522	Integral membrane protein (intg_mem_TP0381)
GE376_04195	COG1114	Component of the transport system for branched-chain amino acids
GE376_04200	COG3546	catalase activity
GE376_04235	COG0586	Pfam SNARE associated Golgi protein
GE376_04265	COG0531	amino acid
GE376_04270	COG0475	glutathione-regulated potassium exporter activity
GE376_04280	COG1737	Transcriptional regulator
GE376_04290	COG1263	PTS System
GE376_04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_04300	COG2259	Doxx family
GE376_04320	COG1522	sequence-specific DNA binding
GE376_04325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GE376_04325	COG0165	Argininosuccinate lyase
GE376_04330	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_04340	COG2076	Multidrug Resistance protein
GE376_04345	COG2076	Multidrug Resistance protein
GE376_04350	COG1309	transcriptional regulator
GE376_04355	COG2814	Major facilitator Superfamily
GE376_04360	COG1733	regulation of RNA biosynthetic process
GE376_04375	COG4533	DNA binding
GE376_04380	COG2211	Major facilitator Superfamily
GE376_04390	COG0693	protein deglycase activity
GE376_04405	COG0531	amino acid
GE376_04420	COG1012	belongs to the aldehyde dehydrogenase family
GE376_04435	COG1132	(ABC) transporter
GE376_04440	COG1132	(ABC) transporter
GE376_04450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_04455	COG0765	amino acid transport
GE376_04460	COG1126	abc transporter atp-binding protein
GE376_04475	COG0189	ligase activity
GE376_04510	COG0028	Belongs to the TPP enzyme family
GE376_04515	COG3527	Alpha-acetolactate decarboxylase
GE376_04530	COG0561	phosphatase activity
GE376_04540	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_04540	COG3409	Peptidoglycan-binding domain 1 protein
GE376_04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE376_04550	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_04565	COG0659	secondary active sulfate transmembrane transporter activity
GE376_04570	COG2244	polysaccharide biosynthetic process
GE376_04595	COG1024	Enoyl-CoA hydratase
GE376_04615	COG1363	Peptidase, m42
GE376_04655	COG0601	transmembrane transport
GE376_04660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_04665	COG0444	Belongs to the ABC transporter superfamily
GE376_04670	COG4608	Belongs to the ABC transporter superfamily
GE376_04700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_04730	COG0477	Major facilitator Superfamily
GE376_04735	COG3290	protein histidine kinase activity
GE376_04740	COG4565	transcriptional regulatory protein
GE376_04745	COG3181	Tripartite tricarboxylate transporter family receptor
GE376_04750	COG0494	nUDIX hydrolase
GE376_04765	COG0305	Participates in initiation and elongation during chromosome replication
GE376_04800	COG0477	Major facilitator Superfamily
GE376_04815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_04840	COG1073	alpha beta
GE376_04880	COG1183	phosphatidylcholine synthase activity
GE376_04895	COG2814	Major facilitator Superfamily
GE376_04900	COG0640	Transcriptional regulator
GE376_04915	COG2376	Dihydroxyacetone kinase
GE376_04930	COG2376	Dihydroxyacetone kinase
GE376_04970	COG0457	Tetratricopeptide repeat
GE376_04980	COG2373	Large extracellular alpha-helical protein
GE376_05010	COG0596	Alpha beta hydrolase
GE376_05045	COG3237	CsbD-like
GE376_05070	COG1191	sigma factor activity
GE376_05080	COG2208	phosphoserine phosphatase activity
GE376_05085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE376_05090	COG0784	Response regulator, receiver
GE376_05090	COG5002	protein histidine kinase activity
GE376_05090	COG2205	protein histidine kinase activity
GE376_05125	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GE376_05145	COG0420	3'-5' exonuclease activity
GE376_05150	COG4717	serine-type aminopeptidase activity
GE376_05165	COG1280	lysine exporter protein (LysE YggA)
GE376_05170	COG0346	lactoylglutathione lyase activity
GE376_05175	COG0346	lactoylglutathione lyase activity
GE376_05180	COG0457	Tetratricopeptide repeat
GE376_05190	COG2267	carboxylic ester hydrolase activity
GE376_05215	COG2140	Oxalate decarboxylase
GE376_05220	COG3620	sequence-specific DNA binding
GE376_05225	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GE376_05230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE376_05240	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GE376_05245	COG1695	Transcriptional regulator
GE376_05255	COG1595	DNA-templated transcription, initiation
GE376_05275	COG2409	Drug exporters of the RND superfamily
GE376_05275	COG1033	growth of symbiont in host cell
GE376_05280	COG3973	AAA domain
GE376_05315	COG4980	gas vesicle protein
GE376_05320	COG0537	adenosine 5'-monophosphoramidase activity
GE376_05325	COG1131	(ABC) transporter
GE376_05330	COG4473	ABC transporter
GE376_05390	COG1309	transcriptional regulator
GE376_05395	COG3402	PFAM membrane-flanked domain
GE376_05400	COG3428	Bacterial PH domain
GE376_05445	COG0697	spore germination
GE376_05450	COG3402	PFAM membrane-flanked domain
GE376_05455	COG3428	Bacterial PH domain
GE376_05460	COG2329	Antibiotic biosynthesis monooxygenase
GE376_05465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_05515	COG1309	transcriptional regulator
GE376_05520	COG1511	domain protein
GE376_05545	COG1609	Transcriptional regulator
GE376_05555	COG1234	tRNA 3'-trailer cleavage
GE376_05560	COG0095	Lipoate-protein ligase
GE376_05570	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_05580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GE376_05590	COG4208	sulfate ABC transporter
GE376_05610	COG1408	metallophosphoesterase
GE376_05620	COG1078	dGTPase activity
GE376_05630	COG1595	DNA-templated transcription, initiation
GE376_05635	COG2207	Transcriptional regulator
GE376_05635	COG3708	Transcriptional regulator
GE376_05645	COG2205	protein histidine kinase activity
GE376_05650	COG0745	RESPONSE REGULATOR receiver
GE376_05670	COG0501	Belongs to the peptidase M48B family
GE376_05675	COG0840	transmembrane signaling receptor activity
GE376_05685	COG3693	PFAM glycoside hydrolase, family 10
GE376_05695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GE376_05700	COG2224	Isocitrate lyase
GE376_05715	COG1278	Cold shock
GE376_05735	COG0398	Pfam SNARE associated Golgi protein
GE376_05755	COG0202	RNA polymerase activity
GE376_05795	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE376_05820	COG0367	asparagine synthase
GE376_05830	COG0753	catalase activity
GE376_05835	COG0004	ammonium transporteR
GE376_05860	COG2996	Protein conserved in bacteria
GE376_05875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_05890	COG0561	phosphatase activity
GE376_05910	COG2267	carboxylic ester hydrolase activity
GE376_05925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_05930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE376_05935	COG5504	Zn-dependent protease
GE376_05945	COG0180	Tryptophanyl-tRNA synthetase
GE376_05960	COG4166	transmembrane transport
GE376_05965	COG0601	transmembrane transport
GE376_05970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_05975	COG0444	Belongs to the ABC transporter superfamily
GE376_05980	COG4608	Belongs to the ABC transporter superfamily
GE376_05985	COG0534	Mate efflux family protein
GE376_05990	COG4166	transmembrane transport
GE376_06005	COG1393	Belongs to the ArsC family
GE376_06010	COG0861	Integral membrane protein TerC family
GE376_06020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_06030	COG1164	Oligoendopeptidase f
GE376_06040	COG2346	COG2346, Truncated hemoglobins
GE376_06045	COG4116	CYTH
GE376_06055	COG2357	RelA SpoT domain protein
GE376_06065	COG0564	pseudouridine synthase activity
GE376_06080	COG0772	Belongs to the SEDS family
GE376_06085	COG1216	Glycosyl transferase, family 2
GE376_06105	COG0457	Tetratricopeptide repeat
GE376_06105	COG0463	Glycosyl transferase, family 2
GE376_06125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE376_06140	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE376_06185	COG2153	protein acetylation
GE376_06195	COG2382	esterase
GE376_06215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_06225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GE376_06225	COG0512	Glutamine amidotransferase of anthranilate synthase
GE376_06260	COG1620	l-lactate permease
GE376_06265	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_06280	COG4640	response to antibiotic
GE376_06305	COG2226	methyltransferase
GE376_06325	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_06335	COG1476	TRANSCRIPTIONal
GE376_06400	COG2226	methyltransferase
GE376_06410	COG1686	Belongs to the peptidase S11 family
GE376_06415	COG0681	Belongs to the peptidase S26 family
GE376_06450	COG1012	belongs to the aldehyde dehydrogenase family
GE376_06460	COG1176	ABC-type spermidine putrescine transport system, permease component I
GE376_06465	COG1177	transmembrane transport
GE376_06470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GE376_06480	COG2409	Drug exporters of the RND superfamily
GE376_06490	COG0564	pseudouridine synthase activity
GE376_06500	COG2340	Cysteine-rich secretory protein family
GE376_06505	COG0247	lactate metabolic process
GE376_06510	COG0277	FAD linked oxidase domain protein
GE376_06515	COG3835	regulator
GE376_06525	COG0745	RESPONSE REGULATOR receiver
GE376_06530	COG5002	protein histidine kinase activity
GE376_06535	COG2186	Transcriptional regulator
GE376_06555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GE376_06565	COG2116	formate transmembrane transporter activity
GE376_06570	COG0861	Integral membrane protein TerC family
GE376_06575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_06585	COG2030	dehydratase
GE376_06605	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_06610	COG3243	poly(R)-hydroxyalkanoic acid synthase
GE376_06620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_06635	COG1840	ABC-type Fe3 transport system, periplasmic component
GE376_06640	COG3842	ATPase activity
GE376_06665	COG1349	DNA-binding transcription factor activity
GE376_06675	COG0235	Class ii aldolase
GE376_06685	COG2861	carbohydrate metabolic process
GE376_06695	COG3852	Histidine kinase
GE376_06700	COG1846	Transcriptional regulator
GE376_06710	COG2318	DinB family
GE376_06715	COG5002	protein histidine kinase activity
GE376_06725	COG0720	synthase
GE376_06740	COG4873	Protein conserved in bacteria
GE376_06770	COG1780	Probably involved in ribonucleotide reductase function
GE376_06775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE376_06780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE376_06785	COG1725	Transcriptional regulator
GE376_06790	COG1131	(ABC) transporter
GE376_06800	COG1131	(ABC) transporter
GE376_06820	COG1522	sequence-specific DNA binding
GE376_06830	COG1335	isochorismatase
GE376_06840	COG1619	proteins homologs of microcin C7 resistance protein MccF
GE376_06845	COG2070	2-Nitropropane dioxygenase
GE376_06850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE376_06860	COG1696	Membrane protein involved in D-alanine export
GE376_06880	COG0716	FMN binding
GE376_06925	COG1846	Transcriptional regulator
GE376_06935	COG1301	dicarboxylic acid transport
GE376_06940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_06945	COG4709	membrane
GE376_06950	COG3874	Sporulation protein YtfJ
GE376_06970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_06975	COG0028	Belongs to the TPP enzyme family
GE376_06980	COG0440	acetolactate synthase activity
GE376_07055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE376_07070	COG1183	phosphatidylcholine synthase activity
GE376_07075	COG1368	sulfuric ester hydrolase activity
GE376_07085	COG0019	diaminopimelate decarboxylase activity
GE376_07105	COG0529	Catalyzes the synthesis of activated sulfate
GE376_07110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_07130	COG1648	precorrin-2 dehydrogenase activity
GE376_07135	COG0733	neurotransmitter:sodium symporter activity
GE376_07155	COG1757	Na H antiporter
GE376_07170	COG4758	membrane
GE376_07175	COG4585	Histidine kinase
GE376_07180	COG2197	response regulator
GE376_07190	COG1114	Component of the transport system for branched-chain amino acids
GE376_07200	COG2226	methyltransferase
GE376_07240	COG0730	response to heat
GE376_07245	COG0306	phosphate transporter
GE376_07250	COG1392	Phosphate transport regulator
GE376_07255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_07270	COG3852	Histidine kinase
GE376_07275	COG1801	Protein of unknown function DUF72
GE376_07285	COG0582	viral genome integration into host DNA
GE376_07290	COG5002	protein histidine kinase activity
GE376_07305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GE376_07305	COG0392	lysyltransferase activity
GE376_07320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GE376_07325	COG1686	Belongs to the peptidase S11 family
GE376_07330	COG2715	membrane protein required for spore maturation
GE376_07335	COG0700	Nucleoside recognition
GE376_07340	COG1187	pseudouridine synthase activity
GE376_07350	COG1333	cytochrome c biogenesis protein
GE376_07355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE376_07360	COG0745	RESPONSE REGULATOR receiver
GE376_07365	COG5002	protein histidine kinase activity
GE376_07370	COG2096	Adenosyltransferase
GE376_07385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GE376_07390	COG1141	Ferredoxin
GE376_07400	COG0514	ATP-dependent DNA helicase (RecQ)
GE376_07405	COG1266	CAAX protease self-immunity
GE376_07415	COG1408	metallophosphoesterase
GE376_07420	COG0789	Transcriptional regulator
GE376_07430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE376_07450	COG0492	ferredoxin-NADP+ reductase activity
GE376_07455	COG0252	asparaginase activity
GE376_07525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_07540	COG0142	geranyltranstransferase activity
GE376_07550	COG0142	geranyltranstransferase activity
GE376_07575	COG0457	Tetratricopeptide repeat
GE376_07595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GE376_07600	COG2010	Cytochrome c
GE376_07600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GE376_07605	COG4347	Protein of unknown function (DUF1405)
GE376_07620	COG2738	Putative neutral zinc metallopeptidase
GE376_07630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_07640	COG1694	Mazg nucleotide pyrophosphohydrolase
GE376_07660	COG0438	transferase activity, transferring glycosyl groups
GE376_07695	COG1199	ATP-dependent helicase activity
GE376_07695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GE376_07715	COG3935	DnaD domain protein
GE376_07720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GE376_07730	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_07730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_07785	COG0116	Belongs to the methyltransferase superfamily
GE376_07795	COG1199	ATP-dependent helicase activity
GE376_07800	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GE376_07810	COG0024	Methionine aminopeptidase
GE376_07825	COG2233	PERMEase
GE376_07830	COG2311	Membrane
GE376_07835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_07845	COG0456	acetyltransferase
GE376_07900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_07915	COG3944	biosynthesis protein
GE376_07925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE376_07940	COG1215	transferase activity, transferring glycosyl groups
GE376_07945	COG0438	transferase activity, transferring glycosyl groups
GE376_07960	COG0454	-acetyltransferase
GE376_07980	COG0328	RNA-DNA hybrid ribonuclease activity
GE376_08015	COG3403	YqcI/YcgG family
GE376_08020	COG1280	lysine exporter protein (LysE YggA)
GE376_08040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_08045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_08055	COG0475	glutathione-regulated potassium exporter activity
GE376_08060	COG0789	Transcriptional regulator
GE376_08060	COG4978	Transcriptional regulator
GE376_08070	COG2323	membrane
GE376_08075	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GE376_08135	COG1923	regulation of RNA biosynthetic process
GE376_08145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GE376_08150	COG1360	Flagellar Motor Protein
GE376_08155	COG2201	protein-glutamate methylesterase activity
GE376_08160	COG0643	Histidine kinase
GE376_08160	COG2198	Histidine kinase
GE376_08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_08165	COG1776	CheC inhibitor of MCP methylation
GE376_08180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE376_08200	COG1256	bacterial-type flagellum assembly
GE376_08205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_08210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GE376_08225	COG1815	bacterial-type flagellum-dependent cell motility
GE376_08230	COG1558	bacterial-type flagellum-dependent cell motility
GE376_08235	COG1677	Flagellar hook-basal body complex protein FliE
GE376_08240	COG1766	The M ring may be actively involved in energy transduction
GE376_08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_08255	COG1157	protein secretion by the type III secretion system
GE376_08275	COG1749	Flagellar hook protein flgE
GE376_08290	COG0784	Response regulator, receiver
GE376_08290	COG0835	chemotaxis
GE376_08300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_08305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_08310	COG0741	lytic transglycosylase activity
GE376_08320	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_08325	COG1776	CheC inhibitor of MCP methylation
GE376_08325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_08335	COG1338	Plays a role in the flagellum-specific transport system
GE376_08340	COG1987	bacterial-type flagellum assembly
GE376_08350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE376_08355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE376_08360	COG1419	protein localization to endoplasmic reticulum
GE376_08365	COG4786	Flagellar basal body rod
GE376_08375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GE376_08410	COG2329	Antibiotic biosynthesis monooxygenase
GE376_08445	COG3842	ATPase activity
GE376_08455	COG1177	transmembrane transport
GE376_08460	COG1234	tRNA 3'-trailer cleavage
GE376_08525	COG0367	asparagine synthase
GE376_08555	COG1802	Transcriptional regulator
GE376_08560	COG0697	spore germination
GE376_08570	COG0523	cobalamin synthesis protein
GE376_08580	COG0701	Predicted permease
GE376_08595	COG1757	Na H antiporter
GE376_08600	COG0789	Transcriptional regulator
GE376_08625	COG0534	Mate efflux family protein
GE376_08630	COG3340	Belongs to the peptidase S51 family
GE376_08650	COG0785	Cytochrome C biogenesis protein
GE376_08655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_08685	COG2733	membrane
GE376_08725	COG1131	(ABC) transporter
GE376_08740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_08745	COG0528	UMP kinase activity
GE376_08755	COG1027	Aspartate ammonia-lyase
GE376_08760	COG0281	malic enzyme
GE376_08765	COG4191	Histidine kinase
GE376_08770	COG0784	Response regulator, receiver
GE376_08775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_08840	COG1695	Transcriptional regulator
GE376_08850	COG0477	Major facilitator Superfamily
GE376_08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE376_08870	COG2223	nitrite transmembrane transporter activity
GE376_08875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_08895	COG0733	neurotransmitter:sodium symporter activity
GE376_08905	COG5566	PFAM Mor transcription activator
GE376_08910	COG2323	membrane
GE376_08930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_08940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_08945	COG0028	Belongs to the TPP enzyme family
GE376_08965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GE376_08990	COG2814	Major facilitator Superfamily
GE376_08995	COG3384	dioxygenase
GE376_09005	COG3279	Response regulator of the LytR AlgR family
GE376_09010	COG0427	acetyl-CoA hydrolase
GE376_09030	COG2814	Major facilitator Superfamily
GE376_09035	COG1309	transcriptional regulator
GE376_09040	COG4166	transmembrane transport
GE376_09085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_09090	COG0745	RESPONSE REGULATOR receiver
GE376_09110	COG1914	H( )-stimulated, divalent metal cation uptake system
GE376_09125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GE376_09130	COG0531	amino acid
GE376_09155	COG2309	aminopeptidase activity
GE376_09170	COG0456	acetyltransferase
GE376_09185	COG1266	CAAX protease self-immunity
GE376_09190	COG1309	transcriptional regulator
GE376_09195	COG2390	Transcriptional regulator
GE376_09205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_09210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GE376_09220	COG4846	Membrane protein involved in cytochrome C biogenesis
GE376_09240	COG0583	DNA-binding transcription factor activity
GE376_09255	COG0006	proline dipeptidase activity
GE376_09265	COG2132	Multicopper oxidase
GE376_09300	COG1114	Component of the transport system for branched-chain amino acids
GE376_09310	COG1276	copper resistance
GE376_09310	COG2372	response to copper ion
GE376_09315	COG4549	nuclear export factor GLE1
GE376_09320	COG0697	spore germination
GE376_09325	COG0583	DNA-binding transcription factor activity
GE376_09330	COG1959	2 iron, 2 sulfur cluster binding
GE376_09335	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GE376_09340	COG0778	Nitroreductase
GE376_09350	COG0628	permease
GE376_09360	COG1231	oxidoreductase activity
GE376_09370	COG0523	cobalamin synthesis protein
GE376_09380	COG0411	ABC transporter
GE376_09400	COG0583	DNA-binding transcription factor activity
GE376_09410	COG1942	4-Oxalocrotonate Tautomerase
GE376_09430	COG1271	oxidase subunit
GE376_09435	COG1294	oxidase, subunit
GE376_09440	COG4988	ABC transporter
GE376_09445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GE376_09455	COG1216	Glycosyl transferase, family 2
GE376_09495	COG1686	Belongs to the peptidase S11 family
GE376_09510	COG1388	LysM domain
GE376_09510	COG0791	NLP P60 protein
GE376_09520	COG1132	(ABC) transporter
GE376_09525	COG0745	RESPONSE REGULATOR receiver
GE376_09530	COG5002	protein histidine kinase activity
GE376_09540	COG0300	oxidoreductase activity
GE376_09555	COG0726	polysaccharide deacetylase
GE376_09575	COG0460	homoserine dehydrogenase
GE376_09600	COG1316	TRANSCRIPTIONal
GE376_09610	COG0745	RESPONSE REGULATOR receiver
GE376_09615	COG5002	protein histidine kinase activity
GE376_09620	COG0726	polysaccharide deacetylase
GE376_09630	COG1285	pathogenesis
GE376_09635	COG1247	-acetyltransferase
GE376_09645	COG4264	IucA IucC family
GE376_09650	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_09665	COG1082	Xylose isomerase domain protein TIM barrel
GE376_09675	COG2814	Major facilitator Superfamily
GE376_09680	COG1279	arginine transmembrane transporter activity
GE376_09685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_09695	COG1752	Esterase of the alpha-beta hydrolase superfamily
GE376_09730	COG0577	efflux transmembrane transporter activity
GE376_09735	COG2002	toxin-antitoxin pair type II binding
GE376_09740	COG1404	Belongs to the peptidase S8 family
GE376_09745	COG0640	Transcriptional regulator
GE376_09750	COG0667	Aldo Keto reductase
GE376_09755	COG2814	Major facilitator Superfamily
GE376_09780	COG0840	transmembrane signaling receptor activity
GE376_09795	COG3949	Membrane
GE376_09800	COG0783	Belongs to the Dps family
GE376_09815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_09825	COG1231	oxidoreductase activity
GE376_09830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_09835	COG4989	oxidoreductase activity
GE376_09840	COG0523	cobalamin synthesis protein
GE376_09845	COG0456	acetyltransferase
GE376_09850	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE376_09855	COG0702	epimerase
GE376_09865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE376_09875	COG4166	transmembrane transport
GE376_09900	COG5337	Spore coat protein CotH
GE376_09905	COG1051	belongs to the nudix hydrolase family
GE376_09910	COG0586	Pfam SNARE associated Golgi protein
GE376_09915	COG2244	polysaccharide biosynthetic process
GE376_09925	COG0701	Predicted permease
GE376_09930	COG3689	TIGRFAM TIGR03943 family protein
GE376_09935	COG1607	acyl-coa hydrolase
GE376_09945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_09960	COG0702	epimerase
GE376_09965	COG2839	Protein conserved in bacteria
GE376_09970	COG1253	flavin adenine dinucleotide binding
GE376_09995	COG1114	Component of the transport system for branched-chain amino acids
GE376_10000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE376_10020	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_10035	COG1876	peptidase activity
GE376_10050	COG2211	Major facilitator Superfamily
GE376_10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_10075	COG0561	phosphatase activity
GE376_10080	COG1846	Transcriptional regulator
GE376_10085	COG2814	Major facilitator Superfamily
GE376_10095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GE376_10115	COG1819	glycosyl
GE376_10120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_10155	COG0456	acetyltransferase
GE376_10205	COG3874	Sporulation protein YtfJ
GE376_10230	COG2226	methyltransferase
GE376_10250	COG1082	Xylose isomerase domain protein TIM barrel
GE376_10255	COG0346	lactoylglutathione lyase activity
GE376_10265	COG0604	alcohol dehydrogenase
GE376_10270	COG1595	DNA-templated transcription, initiation
GE376_10285	COG0426	domain, Protein
GE376_10285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE376_10295	COG0386	Belongs to the glutathione peroxidase family
GE376_10300	COG1305	Transglutaminase-like
GE376_10305	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GE376_10310	COG0714	Associated with various cellular activities
GE376_10315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GE376_10320	COG1140	nitrate reductase beta subunit
GE376_10325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GE376_10330	COG2181	nitrate reductase activity
GE376_10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_10340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GE376_10345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_10350	COG0303	'Molybdopterin
GE376_10355	COG0314	molybdopterin synthase activity
GE376_10365	COG2223	nitrite transmembrane transporter activity
GE376_10380	COG1648	precorrin-2 dehydrogenase activity
GE376_10390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GE376_10390	COG1587	Uroporphyrinogen-III synthase
GE376_10395	COG2146	nitrite reductase [NAD(P)H] activity
GE376_10400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_10405	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GE376_10440	COG2359	stage V sporulation protein S
GE376_10475	COG5444	nuclease activity
GE376_10485	COG2856	Zn peptidase
GE376_10515	COG1396	sequence-specific DNA binding
GE376_10590	COG0582	viral genome integration into host DNA
GE376_10600	COG1278	Cold shock
GE376_10620	COG0582	viral genome integration into host DNA
GE376_10635	COG5484	DNA packaging
GE376_10640	COG1783	phage Terminase large subunit
GE376_10655	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GE376_10785	COG0457	Tetratricopeptide repeat
GE376_10810	COG1418	mRNA catabolic process
GE376_10815	COG0488	(ABC) transporter
GE376_10830	COG0629	single-stranded DNA binding
GE376_10840	COG1413	lyase activity
GE376_10855	COG2136	Putative SAM-dependent methyltransferase
GE376_10855	COG2521	methyltransferase
GE376_10860	COG0018	arginyl-trna synthetase
GE376_10900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE376_10905	COG0017	Asparaginyl-tRNA synthetase
GE376_10925	COG1674	ftsk spoiiie
GE376_11000	COG0733	neurotransmitter:sodium symporter activity
GE376_11025	COG2610	gluconate transmembrane transporter activity
GE376_11035	COG1794	racemase activity, acting on amino acids and derivatives
GE376_11045	COG0456	acetyltransferase
GE376_11055	COG3655	Transcriptional regulator
GE376_11060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GE376_11070	COG1131	(ABC) transporter
GE376_11075	COG4473	ABC transporter
GE376_11085	COG0546	phosphoglycolate phosphatase activity
GE376_11100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_11115	COG0768	penicillin binding
GE376_11125	COG0204	Acyl-transferase
GE376_11130	COG1272	protein, Hemolysin III
GE376_11140	COG0805	protein transport
GE376_11150	COG1307	EDD domain protein, DegV family
GE376_11160	COG1999	signal sequence binding
GE376_11165	COG0071	Belongs to the small heat shock protein (HSP20) family
GE376_11170	COG0367	asparagine synthase
GE376_11185	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_11190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_11195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_11215	COG1335	isochorismatase
GE376_11225	COG0668	transmembrane transport
GE376_11230	COG2203	Gaf domain
GE376_11230	COG4585	Histidine kinase
GE376_11235	COG2197	response regulator
GE376_11240	COG1737	Transcriptional regulator
GE376_11245	COG0384	phenazine biosynthesis protein PhzF
GE376_11250	COG1064	alcohol dehydrogenase
GE376_11275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GE376_11310	COG1125	glycine betaine transport
GE376_11310	COG0517	IMP dehydrogenase activity
GE376_11315	COG1174	glycine betaine transport
GE376_11350	COG1253	flavin adenine dinucleotide binding
GE376_11355	COG1012	belongs to the aldehyde dehydrogenase family
GE376_11360	COG5506	Protein of unknown function (DUF1694)
GE376_11375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_11380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GE376_11385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GE376_11390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_11395	COG0456	acetyltransferase
GE376_11400	COG3829	transcription factor binding
GE376_11405	COG1509	lysine 2,3-aminomutase activity
GE376_11440	COG3064	Membrane
GE376_11440	COG4991	sh3 domain protein
GE376_11440	COG0515	serine threonine protein kinase
GE376_11445	COG4326	sporulation control protein
GE376_11450	COG0671	phosphoesterase, PA-phosphatase related
GE376_11455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE376_11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_11535	COG0300	oxidoreductase activity
GE376_11555	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_11555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_11565	COG2814	Major facilitator Superfamily
GE376_11570	COG4841	protein insertion into membrane
GE376_11575	COG0372	Belongs to the citrate synthase family
GE376_11580	COG2079	MmgE PrpD family protein
GE376_11585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GE376_11590	COG1960	acyl-CoA dehydrogenase activity
GE376_11595	COG2084	Dehydrogenase
GE376_11605	COG1280	lysine exporter protein (LysE YggA)
GE376_11610	COG1024	Enoyl-CoA hydratase
GE376_11625	COG0420	3'-5' exonuclease activity
GE376_11630	COG0419	ATPase involved in DNA repair
GE376_11660	COG2223	nitrite transmembrane transporter activity
GE376_11665	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_11670	COG1169	isochorismate synthase
GE376_11675	COG1021	2,3-dihydroxybenzoate-AMP ligase
GE376_11680	COG1535	isochorismatase
GE376_11680	COG3433	isochorismatase activity
GE376_11685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_11690	COG3251	PFAM MbtH domain protein
GE376_11695	COG2814	Major facilitator Superfamily
GE376_11710	COG0776	regulation of translation
GE376_11720	COG2318	DinB family
GE376_11730	COG1115	amino acid carrier protein
GE376_11750	COG1187	pseudouridine synthase activity
GE376_11755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE376_11760	COG1136	(ABC) transporter
GE376_11770	COG2814	Major facilitator Superfamily
GE376_11785	COG0028	Belongs to the TPP enzyme family
GE376_11820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_11835	COG1846	Transcriptional regulator
GE376_11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_11880	COG1247	-acetyltransferase
GE376_11920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_11950	COG0583	DNA-binding transcription factor activity
GE376_11955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GE376_11975	COG0583	DNA-binding transcription factor activity
GE376_11980	COG2258	MOSC domain
GE376_11995	COG1132	(ABC) transporter
GE376_12000	COG1132	(ABC) transporter
GE376_12040	COG0582	viral genome integration into host DNA
GE376_12070	COG5484	DNA packaging
GE376_12085	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_12115	COG1396	sequence-specific DNA binding
GE376_12150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_12155	COG1595	DNA-templated transcription, initiation
GE376_12175	COG1649	PFAM Uncharacterised BCR, COG1649
GE376_12200	COG2971	BadF BadG BcrA BcrD
GE376_12220	COG1846	Transcriptional regulator
GE376_12235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_12255	COG1309	transcriptional regulator
GE376_12275	COG3615	Tellurite resistance protein tehB
GE376_12275	COG0500	methyltransferase
GE376_12290	COG3961	Belongs to the TPP enzyme family
GE376_12295	COG1846	Transcriptional regulator
GE376_12325	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE376_12360	COG2002	toxin-antitoxin pair type II binding
GE376_12370	COG0730	response to heat
GE376_12375	COG0110	maltose O-acetyltransferase activity
GE376_12380	COG1686	Belongs to the peptidase S11 family
GE376_12395	COG2814	Major facilitator Superfamily
GE376_12435	COG1115	amino acid carrier protein
GE376_12445	COG4191	Histidine kinase
GE376_12450	COG0784	Response regulator, receiver
GE376_12460	COG0697	spore germination
GE376_12465	COG0531	amino acid
GE376_12475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_12480	COG0531	amino acid
GE376_12485	COG0322	excinuclease ABC activity
GE376_12505	COG2207	Transcriptional regulator
GE376_12530	COG5002	protein histidine kinase activity
GE376_12620	COG1760	l-serine dehydratase
GE376_12625	COG1760	l-serine dehydratase
GE376_12630	COG0814	amino acid
GE376_12665	COG1309	transcriptional regulator
GE376_12695	COG4224	UPF0291 protein
GE376_12700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_12705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GE376_12710	COG1278	Cold shock
GE376_12725	COG1329	Transcriptional regulator
GE376_12770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GE376_12775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_12795	COG0768	penicillin binding
GE376_12800	COG1595	DNA-templated transcription, initiation
GE376_12825	COG1408	metallophosphoesterase
GE376_12835	COG1131	(ABC) transporter
GE376_12845	COG1309	transcriptional regulator
GE376_12860	COG1960	acyl-CoA dehydrogenase activity
GE376_12865	COG0439	Biotin carboxylase
GE376_12870	COG0511	ligase activity, forming carbon-carbon bonds
GE376_12875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GE376_12880	COG1024	Enoyl-CoA hydratase
GE376_12885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GE376_12890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_12925	COG1686	Belongs to the peptidase S11 family
GE376_12965	COG3227	Zinc metalloprotease (Elastase)
GE376_12970	COG2207	Transcriptional regulator
GE376_13000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GE376_13010	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_13015	COG1733	regulation of RNA biosynthetic process
GE376_13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_13070	COG2368	4-hydroxyphenylacetate
GE376_13085	COG1063	alcohol dehydrogenase
GE376_13095	COG2323	membrane
GE376_13105	COG0693	protein deglycase activity
GE376_13115	COG3386	PFAM SMP-30 Gluconolaconase
GE376_13125	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GE376_13130	COG3773	Cell wall hydrolase
GE376_13140	COG0745	RESPONSE REGULATOR receiver
GE376_13145	COG2205	protein histidine kinase activity
GE376_13175	COG1136	(ABC) transporter
GE376_13180	COG0577	efflux transmembrane transporter activity
GE376_13200	COG0460	homoserine dehydrogenase
GE376_13205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_13215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GE376_13240	COG0582	viral genome integration into host DNA
GE376_13255	COG1396	sequence-specific DNA binding
GE376_13275	COG2002	toxin-antitoxin pair type II binding
GE376_13340	COG0582	viral genome integration into host DNA
GE376_13380	COG4626	Terminase
GE376_13380	COG1802	Transcriptional regulator
GE376_13390	COG0740	serine-type endopeptidase activity
GE376_13475	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_13530	COG2124	cytochrome p450
GE376_13570	COG0561	phosphatase activity
GE376_13575	COG5002	protein histidine kinase activity
GE376_13590	COG1819	glycosyl
GE376_13595	COG1794	racemase activity, acting on amino acids and derivatives
GE376_13620	COG2205	protein histidine kinase activity
GE376_13625	COG0582	viral genome integration into host DNA
GE376_13695	COG0745	RESPONSE REGULATOR receiver
GE376_13700	COG5002	protein histidine kinase activity
GE376_13705	COG0604	alcohol dehydrogenase
GE376_13710	COG0671	phosphoesterase, PA-phosphatase related
GE376_13765	COG0789	Transcriptional regulator
GE376_13770	COG2814	Major facilitator Superfamily
GE376_13785	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_13805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_13810	COG0697	spore germination
GE376_13850	COG2223	nitrite transmembrane transporter activity
GE376_13865	COG0592	DNA-directed DNA polymerase activity
GE376_13905	COG3878	Protein conserved in bacteria
GE376_13930	COG4667	esterase of the alpha-beta hydrolase superfamily
GE376_13970	COG0322	excinuclease ABC activity
GE376_14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_14045	COG0745	RESPONSE REGULATOR receiver
GE376_14050	COG5002	protein histidine kinase activity
GE376_14065	COG1522	sequence-specific DNA binding
GE376_14080	COG1136	(ABC) transporter
GE376_14085	COG0577	efflux transmembrane transporter activity
GE376_14090	COG1073	alpha beta
GE376_14095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_14110	COG1523	belongs to the glycosyl hydrolase 13 family
GE376_14115	COG3227	Zinc metalloprotease (Elastase)
GE376_14120	COG0737	Belongs to the 5'-nucleotidase family
GE376_14135	COG0201	protein transport
GE376_14150	COG0697	spore germination
GE376_14155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_14165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GE376_14195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_14210	COG2959	enzyme of heme biosynthesis
GE376_14215	COG3409	Peptidoglycan-binding domain 1 protein
GE376_14215	COG3773	Cell wall hydrolase
GE376_14255	COG1309	transcriptional regulator
GE376_14290	COG3284	Transcriptional regulator
GE376_14305	COG1349	DNA-binding transcription factor activity
GE376_14320	COG1959	2 iron, 2 sulfur cluster binding
GE376_14335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_14340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_14345	COG0022	dehydrogenase e1 component
GE376_14350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_14360	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_14390	COG4176	ABC-type proline glycine betaine transport system permease component
GE376_14395	COG4175	Glycine betaine
GE376_14395	COG0517	IMP dehydrogenase activity
GE376_14405	COG0740	serine-type endopeptidase activity
GE376_14425	COG2153	protein acetylation
GE376_14430	COG3397	chitin binding
GE376_14435	COG1819	glycosyl
GE376_14450	COG2205	protein histidine kinase activity
GE376_14455	COG2226	methyltransferase
GE376_14460	COG2315	Protein conserved in bacteria
GE376_14505	COG3973	AAA domain
GE376_14535	COG0514	ATP-dependent DNA helicase (RecQ)
GE376_14565	COG4637	Psort location Cytoplasmic, score
GE376_14590	COG3397	chitin binding
GE376_14605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GE376_14610	COG1115	amino acid carrier protein
GE376_14615	COG1012	belongs to the aldehyde dehydrogenase family
GE376_14620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GE376_14630	COG3938	Belongs to the proline racemase family
GE376_14635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_14680	COG1078	dGTPase activity
GE376_14685	COG0586	Pfam SNARE associated Golgi protein
GE376_14700	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE376_14705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_14710	COG4166	transmembrane transport
GE376_14720	COG4948	Mandelate Racemase Muconate Lactonizing
GE376_14735	COG0667	Aldo Keto reductase
GE376_14785	COG3850	Histidine kinase
GE376_14785	COG5002	protein histidine kinase activity
GE376_14790	COG0745	RESPONSE REGULATOR receiver
GE376_14835	COG1307	EDD domain protein, DegV family
GE376_14875	COG2814	Major facilitator Superfamily
GE376_14885	COG1664	Polymer-forming cytoskeletal
GE376_14890	COG0789	Transcriptional regulator
GE376_14895	COG4533	DNA binding
GE376_14900	COG2814	Major facilitator Superfamily
GE376_14900	COG0477	Major facilitator Superfamily
GE376_14925	COG2261	transglycosylase associated protein
GE376_14940	COG2226	methyltransferase
GE376_14975	COG0436	Aminotransferase
GE376_14980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GE376_14990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GE376_15005	COG1131	(ABC) transporter
GE376_15055	COG0628	permease
GE376_15065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_15070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_15075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_15115	COG2746	aminoglycoside 3-N-acetyltransferase activity
GE376_15125	COG0697	spore germination
GE376_15155	COG4912	Dna alkylation repair
GE376_15160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_15165	COG0346	lactoylglutathione lyase activity
GE376_15180	COG0726	polysaccharide deacetylase
GE376_15185	COG3037	sugar-specific permease SgaT UlaA
GE376_15195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_15200	COG0861	Integral membrane protein TerC family
GE376_15205	COG1368	sulfuric ester hydrolase activity
GE376_15210	COG0488	(ABC) transporter
GE376_15215	COG1033	growth of symbiont in host cell
GE376_15215	COG2409	Drug exporters of the RND superfamily
GE376_15220	COG1309	transcriptional regulator
GE376_15225	COG1051	belongs to the nudix hydrolase family
GE376_15240	COG0287	Prephenate dehydrogenase
GE376_15255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GE376_15255	COG1605	Chorismate mutase
GE376_15310	COG3584	3D domain protein
GE376_15310	COG1388	LysM domain
GE376_15325	COG0277	FAD linked oxidase domain protein
GE376_15350	COG1879	ABC-type sugar transport system periplasmic component
GE376_15355	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE376_15370	COG2390	Transcriptional regulator
GE376_15375	COG1070	Carbohydrate kinase
GE376_15400	COG2329	Antibiotic biosynthesis monooxygenase
GE376_15415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_15430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_15435	COG4187	Peptidase family M20/M25/M40
GE376_15440	COG1414	Transcriptional regulator
GE376_15450	COG0833	amino acid
GE376_15465	COG3239	Fatty acid desaturase
GE376_15475	COG2720	vancomycin resistance protein
GE376_15480	COG1785	Belongs to the alkaline phosphatase family
GE376_15490	COG3655	Transcriptional regulator
GE376_15515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_15520	COG0346	lactoylglutathione lyase activity
GE376_15545	COG0714	Associated with various cellular activities
GE376_15565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GE376_15570	COG0753	catalase activity
GE376_15605	COG0778	Nitroreductase
GE376_15610	COG1846	Transcriptional regulator
GE376_15650	COG1725	Transcriptional regulator
GE376_15675	COG0456	acetyltransferase
GE376_15690	COG0697	spore germination
GE376_15695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_15735	COG0730	response to heat
GE376_15740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_15745	COG0833	amino acid
GE376_15755	COG4335	DNA alkylation repair
GE376_15765	COG5002	protein histidine kinase activity
GE376_15770	COG0745	RESPONSE REGULATOR receiver
GE376_15780	COG1136	(ABC) transporter
GE376_15780	COG0577	efflux transmembrane transporter activity
GE376_15850	COG1984	allophanate hydrolase subunit 2
GE376_15855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GE376_15860	COG1414	Transcriptional regulator
GE376_15875	COG0640	Transcriptional regulator
GE376_15885	COG1960	acyl-CoA dehydrogenase activity
GE376_15910	COG0542	response to heat
GE376_15950	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GE376_15975	COG3848	Pyruvate phosphate dikinase
GE376_15975	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_15980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_16000	COG1063	alcohol dehydrogenase
GE376_16010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_16020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GE376_16035	COG0737	Belongs to the 5'-nucleotidase family
GE376_16040	COG2267	carboxylic ester hydrolase activity
GE376_16045	COG1335	isochorismatase
GE376_16065	COG0583	DNA-binding transcription factor activity
GE376_16070	COG1846	Transcriptional regulator
GE376_16090	COG0598	Magnesium transport protein CorA
GE376_16130	COG0814	amino acid
GE376_16135	COG0697	spore germination
GE376_16155	COG0415	Belongs to the DNA photolyase family
GE376_16170	COG0288	reversible hydration of carbon dioxide
GE376_16180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GE376_16185	COG5609	conserved protein (DUF2294)
GE376_16190	COG0726	polysaccharide deacetylase
GE376_16205	COG1575	Belongs to the MenA family. Type 1 subfamily
GE376_16230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_16240	COG0798	PFAM Bile acid sodium symporter
GE376_16245	COG0346	lactoylglutathione lyase activity
GE376_16250	COG0640	Transcriptional regulator
GE376_16260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE376_16270	COG2814	Major facilitator Superfamily
GE376_16285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_16285	COG3320	Male sterility
GE376_16340	COG2814	Major facilitator Superfamily
GE376_16345	COG1309	transcriptional regulator
GE376_16350	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_16355	COG1522	sequence-specific DNA binding
GE376_16370	COG0346	lactoylglutathione lyase activity
GE376_16430	COG0814	amino acid
GE376_16455	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_16455	COG3409	Peptidoglycan-binding domain 1 protein
GE376_16460	COG0583	DNA-binding transcription factor activity
GE376_16520	COG0745	RESPONSE REGULATOR receiver
GE376_16525	COG5002	protein histidine kinase activity
GE376_16525	COG3850	Histidine kinase
GE376_16565	COG1136	(ABC) transporter
GE376_16600	COG2814	Major facilitator Superfamily
GE376_16615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GE376_16630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GE376_16650	COG0577	efflux transmembrane transporter activity
GE376_16670	COG3850	Histidine kinase
GE376_16670	COG5002	protein histidine kinase activity
GE376_16680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_16705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GE376_16760	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_16760	COG3409	Peptidoglycan-binding domain 1 protein
GE376_16780	COG1876	peptidase activity
GE376_16785	COG2843	Capsule synthesis protein
GE376_16795	COG0477	Major facilitator Superfamily
GE376_16810	COG1846	Transcriptional regulator
GE376_16815	COG2814	Major facilitator Superfamily
GE376_16825	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE376_16830	COG1131	(ABC) transporter
GE376_16850	COG2031	fatty acid transporter
GE376_16860	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_16915	COG1288	antiporter activity
GE376_16920	COG2356	endonuclease I
GE376_16950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GE376_16970	COG1733	regulation of RNA biosynthetic process
GE376_16975	COG0778	Nitroreductase
GE376_17005	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_17015	COG1131	(ABC) transporter
GE376_17045	COG1011	Hydrolase
GE376_17075	COG0346	lactoylglutathione lyase activity
GE376_17080	COG1940	carbohydrate kinase activity
GE376_17090	COG0110	maltose O-acetyltransferase activity
GE376_17095	COG0180	Tryptophanyl-tRNA synthetase
GE376_17105	COG0628	permease
GE376_17160	COG1253	flavin adenine dinucleotide binding
GE376_17165	COG0789	Transcriptional regulator
GE376_17175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_17200	COG0697	spore germination
GE376_17210	COG1357	PFAM Pentapeptide repeats (8 copies)
GE376_17215	COG3813	Protein conserved in bacteria
GE376_17220	COG2706	6-phosphogluconolactonase activity
GE376_17225	COG1070	Carbohydrate kinase
GE376_17240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GE376_17245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GE376_17250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GE376_17255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GE376_17260	COG0604	alcohol dehydrogenase
GE376_17265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_17280	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_17295	COG0840	transmembrane signaling receptor activity
GE376_17305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_17305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_17310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE376_17310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE376_17315	COG1733	regulation of RNA biosynthetic process
GE376_17330	COG0656	L-ascorbic acid biosynthetic process
GE376_17335	COG2814	Major facilitator Superfamily
GE376_17360	COG2824	Alkylphosphonate utilization operon protein PhnA
GE376_17365	COG0659	secondary active sulfate transmembrane transporter activity
GE376_17380	COG0814	amino acid
GE376_17415	COG1733	regulation of RNA biosynthetic process
GE376_17420	COG2188	Transcriptional regulator
GE376_17425	COG0673	inositol 2-dehydrogenase activity
GE376_17430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GE376_17435	COG1733	regulation of RNA biosynthetic process
GE376_17440	COG1733	regulation of RNA biosynthetic process
GE376_17465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_17490	COG0384	phenazine biosynthesis protein PhzF
GE376_17495	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_17500	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_17505	COG1733	regulation of RNA biosynthetic process
GE376_17525	COG0726	polysaccharide deacetylase
GE376_17535	COG1191	sigma factor activity
GE376_17545	COG1280	lysine exporter protein (LysE YggA)
GE376_17605	COG1151	hydroxylamine reductase activity
GE376_17615	COG3757	hydrolase, family 25
GE376_17615	COG3409	Peptidoglycan-binding domain 1 protein
GE376_17650	COG2072	flavoprotein involved in K transport
GE376_17685	COG1113	amino acid transport
GE376_17690	COG2814	Major facilitator Superfamily
GE376_17725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GE376_17730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_17745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_17750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_17755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_17760	COG3739	integral membrane protein
GE376_17790	COG0583	DNA-binding transcription factor activity
GE376_17810	COG1193	negative regulation of DNA recombination
GE376_17825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GE376_17830	COG1164	Oligoendopeptidase f
GE376_17855	COG3781	membrane
GE376_17870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_17895	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_17935	COG0640	Transcriptional regulator
GE376_17940	COG0604	alcohol dehydrogenase
GE376_17950	COG0457	Tetratricopeptide repeat
GE376_17960	COG2808	Putative FMN-binding domain
GE376_17980	COG0277	FAD linked oxidase domain protein
GE376_18005	COG1183	phosphatidylcholine synthase activity
GE376_18020	COG1252	NADH dehydrogenase
GE376_18035	COG0823	Involved in the tonB-independent uptake of proteins
GE376_18040	COG3397	chitin binding
GE376_18055	COG0697	spore germination
GE376_18075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_18085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_18095	COG0457	Tetratricopeptide repeat
GE376_18120	COG1404	Belongs to the peptidase S8 family
GE376_18155	COG1309	transcriptional regulator
GE376_18170	COG1876	peptidase activity
GE376_18195	COG3852	Histidine kinase
GE376_18205	COG1285	pathogenesis
GE376_18215	COG2514	catechol 2,3-dioxygenase activity
GE376_18220	COG2720	vancomycin resistance protein
GE376_18245	COG1278	Cold shock
GE376_18255	COG0716	FMN binding
GE376_18265	COG1051	belongs to the nudix hydrolase family
GE376_18285	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_18295	COG0165	Argininosuccinate lyase
GE376_18310	COG4145	pantothenate transmembrane transporter activity
GE376_18320	COG1012	belongs to the aldehyde dehydrogenase family
GE376_18325	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_18335	COG1657	PFAM Prenyltransferase squalene oxidase
GE376_18340	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GE376_18345	COG2962	Rard protein
GE376_18350	COG3326	Membrane
GE376_18365	COG0489	protein tyrosine kinase activity
GE376_18375	COG0314	molybdopterin synthase activity
GE376_18380	COG0303	'Molybdopterin
GE376_18385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_18390	COG2116	formate transmembrane transporter activity
GE376_18400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GE376_18405	COG5609	conserved protein (DUF2294)
GE376_18410	COG2427	Protein of unknown function (DUF1641)
GE376_18415	COG3383	formate dehydrogenase (NAD+) activity
GE376_18420	COG0697	spore germination
GE376_18435	COG0531	amino acid
GE376_18470	COG2226	methyltransferase
GE376_18475	COG4166	transmembrane transport
GE376_18480	COG4166	transmembrane transport
GE376_18485	COG4166	transmembrane transport
GE376_18490	COG1316	TRANSCRIPTIONal
GE376_18500	COG1595	DNA-templated transcription, initiation
GE376_18510	COG1131	(ABC) transporter
GE376_18530	COG0673	inositol 2-dehydrogenase activity
GE376_18535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE376_18540	COG0187	DNA topoisomerase II activity
GE376_18545	COG1832	CoA-binding protein
GE376_18550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_18555	COG0745	RESPONSE REGULATOR receiver
GE376_18575	COG4841	protein insertion into membrane
GE376_18580	COG0824	Thioesterase
GE376_18605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_18615	COG1132	(ABC) transporter
GE376_18620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GE376_18630	COG0726	polysaccharide deacetylase
GE376_18650	COG2211	Major facilitator Superfamily
GE376_18660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GE376_18675	COG0183	Belongs to the thiolase family
GE376_18680	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_18685	COG1268	BioY protein
GE376_18690	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_18700	COG5002	protein histidine kinase activity
GE376_18715	COG1136	(ABC) transporter
GE376_18730	COG1131	(ABC) transporter
GE376_18815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_18830	COG5002	protein histidine kinase activity
GE376_18835	COG0400	carboxylic ester hydrolase activity
GE376_18840	COG0346	lactoylglutathione lyase activity
GE376_18845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_18850	COG0069	glutamate synthase activity
GE376_18855	COG1902	pentaerythritol trinitrate reductase activity
GE376_18860	COG1329	Transcriptional regulator
GE376_18865	COG0010	Belongs to the arginase family
GE376_18890	COG2226	methyltransferase
GE376_18915	COG4846	Membrane protein involved in cytochrome C biogenesis
GE376_18920	COG0785	Cytochrome C biogenesis protein
GE376_18945	COG1131	(ABC) transporter
GE376_18960	COG0583	DNA-binding transcription factor activity
GE376_18970	COG1346	cytolysis
GE376_18985	COG0730	response to heat
GE376_19010	COG1132	(ABC) transporter
GE376_19015	COG1132	(ABC) transporter
GE376_19050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_19055	COG0737	Belongs to the 5'-nucleotidase family
GE376_19065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GE376_19085	COG1695	Transcriptional regulator
GE376_19090	COG0174	glutamine synthetase
GE376_19095	COG0789	Transcriptional regulator
GE376_19100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GE376_19105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE376_19110	COG2860	membrane
GE376_19115	COG0464	growth
GE376_19145	COG1388	LysM domain
GE376_19145	COG3584	3D domain protein
GE376_19160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_19160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_19160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_19165	COG1105	Belongs to the carbohydrate kinase PfkB family
GE376_19170	COG1349	DNA-binding transcription factor activity
GE376_19175	COG1979	alcohol dehydrogenase
GE376_19180	COG2322	membrane
GE376_19190	COG1113	amino acid transport
GE376_19205	COG1408	metallophosphoesterase
GE376_19210	COG2116	formate transmembrane transporter activity
GE376_19225	COG2217	Heavy metal translocating P-type atpase
GE376_19230	COG2608	mercury ion transmembrane transporter activity
GE376_19235	COG1937	Protein conserved in bacteria
GE376_19245	COG2819	hydrolase of the alpha beta superfamily
GE376_19250	COG1120	ATPase activity
GE376_19255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_19260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_19265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_19270	COG0708	Exodeoxyribonuclease III
GE376_19275	COG2169	Transcriptional regulator
GE376_19280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE376_19285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GE376_19295	COG2364	Membrane
GE376_19310	COG2267	carboxylic ester hydrolase activity
GE376_19315	COG5001	Diguanylate cyclase
GE376_19315	COG3300	MHYT domain
GE376_19335	COG1086	Polysaccharide biosynthesis protein
GE376_19355	COG1346	cytolysis
GE376_19365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_19375	COG2188	Transcriptional regulator
GE376_19380	COG2723	6-phospho-beta-galactosidase activity
GE376_19390	COG1404	Belongs to the peptidase S8 family
GE376_19395	COG3773	Cell wall hydrolase
GE376_19410	COG1368	sulfuric ester hydrolase activity
GE376_19415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_19440	COG4550	Control of competence regulator ComK, YlbF/YmcA
GE376_19450	COG1013	pyruvate-flavodoxin oxidoreductase activity
GE376_19455	COG0674	pyruvate-flavodoxin oxidoreductase activity
GE376_19455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GE376_19465	COG2359	stage V sporulation protein S
GE376_19470	COG1692	metallophosphoesterase
GE376_19490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GE376_19495	COG1426	Protein conserved in bacteria
GE376_19510	COG0300	oxidoreductase activity
GE376_19515	COG0612	Peptidase, M16
GE376_19520	COG0612	Peptidase, M16
GE376_19545	COG2188	Transcriptional regulator
GE376_19565	COG0740	serine-type endopeptidase activity
GE376_19570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_19580	COG0527	aspartate kinase activity
GE376_19585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GE376_19590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE376_19605	COG5444	nuclease activity
GE376_19615	COG0582	viral genome integration into host DNA
GE376_19665	COG0305	Participates in initiation and elongation during chromosome replication
GE376_19730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE376_19735	COG1873	PFAM PRC-barrel domain
GE376_19740	COG0612	Peptidase, M16
GE376_19745	COG0726	polysaccharide deacetylase
GE376_19760	COG0196	riboflavin kinase activity
GE376_19775	COG1550	Protein conserved in bacteria
GE376_19785	COG1358	cellular component organization or biogenesis
GE376_19790	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GE376_19795	COG0195	Participates in both transcription termination and antitermination
GE376_19815	COG0750	zinc metalloprotease
GE376_19825	COG4589	Belongs to the CDS family
GE376_19870	COG4974	Belongs to the 'phage' integrase family
GE376_19880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE376_19885	COG0758	DNA mediated transformation
GE376_19890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GE376_19930	COG1837	Belongs to the UPF0109 family
GE376_19940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GE376_19950	COG0552	protein localization to endoplasmic reticulum
GE376_19955	COG1196	nuclear chromosome segregation
GE376_19970	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_19975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE376_19990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GE376_19995	COG1461	Dihydroxyacetone kinase
GE376_20000	COG1302	Protein conserved in bacteria
GE376_20015	COG1564	THIamine pyrophosphokinase
GE376_20020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GE376_20030	COG2815	serine threonine protein kinase
GE376_20030	COG0515	serine threonine protein kinase
GE376_20035	COG0631	protein serine/threonine phosphatase activity
GE376_20045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE376_20045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE376_20060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GE376_20065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE376_20085	COG1561	YicC-like family, N-terminal region
GE376_20090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GE376_20105	COG0006	proline dipeptidase activity
GE376_20125	COG3069	C4-dicarboxylate transmembrane transporter activity
GE376_20190	COG0564	pseudouridine synthase activity
GE376_20210	COG3599	regulation of cell shape
GE376_20215	COG2302	S4 RNA-binding domain
GE376_20220	COG0762	integral membrane protein
GE376_20230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GE376_20240	COG1873	PFAM PRC-barrel domain
GE376_20245	COG1191	sigma factor activity
GE376_20250	COG1191	sigma factor activity
GE376_20260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GE376_20265	COG0849	cell division
GE376_20280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GE376_20285	COG0772	Belongs to the SEDS family
GE376_20305	COG0768	penicillin binding
GE376_20330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GE376_20350	COG1399	metal-binding, possibly nucleic acid-binding protein
GE376_20360	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE376_20365	COG1752	Esterase of the alpha-beta hydrolase superfamily
GE376_20370	COG3314	Sporulation integral membrane protein YlbJ
GE376_20380	COG0742	ribosomal rna small subunit methyltransferase
GE376_20395	COG3679	Belongs to the UPF0342 family
GE376_20400	COG0406	alpha-ribazole phosphatase activity
GE376_20415	COG2340	Cysteine-rich secretory protein family
GE376_20430	COG3336	cytochrome c oxidase
GE376_20465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GE376_20475	COG0772	Belongs to the SEDS family
GE376_20485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GE376_20490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GE376_20500	COG4896	Protein conserved in bacteria
GE376_20525	COG0483	inositol monophosphate 1-phosphatase activity
GE376_20545	COG1982	Orn Lys Arg decarboxylase major
GE376_20595	COG0022	dehydrogenase e1 component
GE376_20600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_20615	COG0561	phosphatase activity
GE376_20630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_20635	COG0569	domain protein
GE376_20655	COG0583	DNA-binding transcription factor activity
GE376_20660	COG0517	IMP dehydrogenase activity
GE376_20670	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GE376_20675	COG4703	Protein of unknown function (DUF1797)
GE376_20690	COG2200	EAL domain
GE376_20695	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_20700	COG1408	metallophosphoesterase
GE376_20745	COG2814	Major facilitator Superfamily
GE376_20765	COG3209	COG3209 Rhs family protein
GE376_20775	COG2205	protein histidine kinase activity
GE376_20785	COG0436	Aminotransferase
GE376_20790	COG1609	Transcriptional regulator
GE376_20795	COG3833	ABC-type maltose transport systems, permease component
GE376_20800	COG1175	transmembrane transport
GE376_20805	COG2182	Extracellular solute-binding protein
GE376_20815	COG0366	Alpha amylase catalytic
GE376_20820	COG3842	ATPase activity
GE376_20860	COG0183	Belongs to the thiolase family
GE376_20895	COG1695	Transcriptional regulator
GE376_20900	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_20920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GE376_20925	COG0436	Aminotransferase
GE376_20960	COG2084	Dehydrogenase
GE376_20970	COG2203	Gaf domain
GE376_20970	COG2199	diguanylate cyclase activity
GE376_20975	COG0778	Nitroreductase
GE376_21000	COG2190	(PTS) system
GE376_21000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_21000	COG1263	PTS System
GE376_21005	COG3711	transcriptional antiterminator
GE376_21025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GE376_21055	COG1547	Domain of unknown function (DUF309)
GE376_21060	COG0456	acetyltransferase
GE376_21065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GE376_21070	COG4086	secreted protein
GE376_21075	COG0561	phosphatase activity
GE376_21080	COG0697	spore germination
GE376_21095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_21120	COG0733	neurotransmitter:sodium symporter activity
GE376_21140	COG1686	Belongs to the peptidase S11 family
GE376_21150	COG1725	Transcriptional regulator
GE376_21155	COG1131	(ABC) transporter
GE376_21175	COG1846	Transcriptional regulator
GE376_21190	COG0598	Magnesium transport protein CorA
GE376_21215	COG4974	Belongs to the 'phage' integrase family
GE376_21225	COG0735	belongs to the Fur family
GE376_21230	COG1300	Membrane
GE376_21250	COG0667	Aldo Keto reductase
GE376_21255	COG0656	L-ascorbic acid biosynthetic process
GE376_21260	COG0456	acetyltransferase
GE376_21260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_21270	COG0737	Belongs to the 5'-nucleotidase family
GE376_21270	COG4085	toxin activity
GE376_21270	COG1525	nuclease
GE376_21280	COG0596	Alpha beta hydrolase
GE376_21285	COG2056	Na+-H+ antiporter family
GE376_21290	COG1609	Transcriptional regulator
GE376_21295	COG0456	acetyltransferase
GE376_21300	COG1073	alpha beta
GE376_21320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_21320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_21325	COG0307	riboflavin synthase, alpha
GE376_21355	COG1073	alpha beta
GE376_21355	COG2226	methyltransferase
GE376_21370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_21385	COG0737	Belongs to the 5'-nucleotidase family
GE376_21395	COG1522	sequence-specific DNA binding
GE376_21440	COG0300	oxidoreductase activity
GE376_21445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_21450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_21455	COG1760	l-serine dehydratase
GE376_21460	COG1760	l-serine dehydratase
GE376_21490	COG1285	pathogenesis
GE376_21505	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE376_21510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_21525	COG1376	ErfK ybiS ycfS ynhG family protein
GE376_21530	COG4129	membrane
GE376_21535	COG1126	abc transporter atp-binding protein
GE376_21540	COG0765	amino acid transport
GE376_21545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_21565	COG2323	membrane
GE376_21570	COG0772	Belongs to the SEDS family
GE376_21575	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_21580	COG0022	dehydrogenase e1 component
GE376_21585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_21590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_21600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE376_21605	COG0280	phosphate acetyltransferase
GE376_21615	COG3290	protein histidine kinase activity
GE376_21615	COG3829	transcription factor binding
GE376_21625	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_21630	COG3093	addiction module antidote protein HigA
GE376_21650	COG0750	zinc metalloprotease
GE376_21655	COG0497	DNA recombination
GE376_21665	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GE376_21675	COG0142	geranyltranstransferase activity
GE376_21700	COG1302	Protein conserved in bacteria
GE376_21705	COG0439	Biotin carboxylase
GE376_21710	COG0511	ligase activity, forming carbon-carbon bonds
GE376_21755	COG3854	ATPases associated with a variety of cellular activities
GE376_21780	COG0006	proline dipeptidase activity
GE376_21795	COG3872	metal-dependent enzyme
GE376_21805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GE376_21840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_21850	COG1609	Transcriptional regulator
GE376_21860	COG2076	Multidrug Resistance protein
GE376_21865	COG2076	Multidrug Resistance protein
GE376_21900	COG1725	Transcriptional regulator
GE376_21935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_22000	COG1459	type II secretion system
GE376_22005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GE376_22075	COG0646	methionine synthase
GE376_22075	COG1410	methionine synthase
GE376_22080	COG0646	methionine synthase
GE376_22080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GE376_22085	COG0626	cystathionine gamma-synthase activity
GE376_22090	COG0626	cystathionine gamma-synthase activity
GE376_22110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_22120	COG1940	carbohydrate kinase activity
GE376_22125	COG4483	Protein conserved in bacteria
GE376_22130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GE376_22140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_22150	COG0704	Plays a role in the regulation of phosphate uptake
GE376_22160	COG0573	inorganic phosphate transmembrane transporter activity
GE376_22165	COG0573	inorganic phosphate transmembrane transporter activity
GE376_22170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GE376_22180	COG0477	Major facilitator Superfamily
GE376_22185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GE376_22195	COG5521	maltodextrose utilization protein MalA
GE376_22210	COG0735	belongs to the Fur family
GE376_22215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE376_22220	COG1121	(ABC) transporter
GE376_22225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_22255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GE376_22260	COG2384	SAM-dependent methyltransferase
GE376_22270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GE376_22275	COG0358	DNA primase activity
GE376_22285	COG0517	IMP dehydrogenase activity
GE376_22300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GE376_22305	COG0295	cytidine deaminase activity
GE376_22310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GE376_22320	COG1480	7TM receptor with intracellular HD hydrolase
GE376_22325	COG1702	phosphate starvation-inducible protein PhoH
GE376_22345	COG1610	YqeY-like protein
GE376_22355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GE376_22360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GE376_22390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE376_22395	COG1733	regulation of RNA biosynthetic process
GE376_22420	COG1466	dna polymerase III delta subunit
GE376_22430	COG2333	competence protein COMEC
GE376_22430	COG0658	competence protein
GE376_22435	COG2131	deaminase
GE376_22440	COG1555	photosystem II stabilization
GE376_22440	COG1596	polysaccharide export
GE376_22445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_22450	COG2226	methyltransferase
GE376_22455	COG0799	negative regulation of ribosome biogenesis
GE376_22460	COG1713	HD superfamily hydrolase involved in NAD metabolism
GE376_22470	COG1534	Rna-binding protein
GE376_22480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE376_22485	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GE376_22500	COG1191	sigma factor activity
GE376_22510	COG1595	DNA-templated transcription, initiation
GE376_22520	COG0778	Nitroreductase
GE376_22525	COG2357	RelA SpoT domain protein
GE376_22535	COG1785	Belongs to the alkaline phosphatase family
GE376_22545	COG2267	carboxylic ester hydrolase activity
GE376_22580	COG1404	Belongs to the peptidase S8 family
GE376_22585	COG3186	Phenylalanine-4-hydroxylase
GE376_22595	COG2514	catechol 2,3-dioxygenase activity
GE376_22600	COG2259	Doxx family
GE376_22640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_22655	COG1012	belongs to the aldehyde dehydrogenase family
GE376_22655	COG1454	alcohol dehydrogenase
GE376_22660	COG0626	cystathionine gamma-synthase activity
GE376_22665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_22690	COG0768	penicillin binding
GE376_22720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GE376_22750	COG0628	permease
GE376_22770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GE376_22785	COG1104	cysteine desulfurase activity
GE376_22790	COG1959	2 iron, 2 sulfur cluster binding
GE376_22795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GE376_22810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GE376_22830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GE376_22840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GE376_22840	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GE376_22845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE376_22850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE376_22850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE376_22860	COG2244	polysaccharide biosynthetic process
GE376_22865	COG2323	membrane
GE376_22875	COG1862	Preprotein translocase
GE376_22905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GE376_22935	COG0157	Belongs to the NadC ModD family
GE376_22940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GE376_22945	COG1104	cysteine desulfurase activity
GE376_22950	COG1827	regulation of RNA biosynthetic process
GE376_22955	COG2258	MOSC domain
GE376_22960	COG0077	Prephenate dehydratase
GE376_22965	COG0577	efflux transmembrane transporter activity
GE376_22970	COG0577	efflux transmembrane transporter activity
GE376_22975	COG1136	(ABC) transporter
GE376_22980	COG5002	protein histidine kinase activity
GE376_22985	COG0745	RESPONSE REGULATOR receiver
GE376_22995	COG3290	protein histidine kinase activity
GE376_23005	COG2868	ribosomal protein
GE376_23015	COG1530	ribonuclease E activity
GE376_23020	COG1994	Peptidase M50
GE376_23025	COG0739	heme binding
GE376_23030	COG2894	cell division
GE376_23045	COG1792	Involved in formation and maintenance of cell shape
GE376_23050	COG1077	Cell shape determining protein MreB Mrl
GE376_23075	COG0285	dihydrofolate synthase activity
GE376_23090	COG1388	LysM domain
GE376_23100	COG0113	porphobilinogen synthase activity
GE376_23105	COG1587	Uroporphyrinogen-III synthase
GE376_23115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE376_23125	COG1846	Transcriptional regulator
GE376_23130	COG1764	response to oxidative stress
GE376_23145	COG0470	DNA polymerase III
GE376_23145	COG1067	ATP-dependent peptidase activity
GE376_23190	COG0622	Phosphoesterase
GE376_23205	COG5401	PFAM Sporulation and spore germination
GE376_23225	COG1309	transcriptional regulator
GE376_23235	COG2197	response regulator
GE376_23240	COG2233	PERMEase
GE376_23245	COG0402	S-adenosylhomocysteine deaminase activity
GE376_23250	COG1983	PspC domain protein
GE376_23255	COG1396	sequence-specific DNA binding
GE376_23260	COG0697	spore germination
GE376_23270	COG1959	2 iron, 2 sulfur cluster binding
GE376_23275	COG1668	transmembrane transport
GE376_23280	COG4152	abc transporter atp-binding protein
GE376_23285	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GE376_23290	COG1360	Flagellar Motor Protein
GE376_23295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GE376_23300	COG1876	peptidase activity
GE376_23305	COG0824	Thioesterase
GE376_23310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GE376_23315	COG1053	succinate dehydrogenase
GE376_23320	COG2009	succinate dehydrogenase
GE376_23325	COG1719	4-vinyl reductase, 4VR
GE376_23335	COG3118	belongs to the thioredoxin family
GE376_23340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GE376_23345	COG2086	electron transfer activity
GE376_23350	COG1024	Enoyl-CoA hydratase
GE376_23355	COG1309	transcriptional regulator
GE376_23360	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_23385	COG2318	DinB family
GE376_23410	COG1131	(ABC) transporter
GE376_23415	COG2205	protein histidine kinase activity
GE376_23420	COG0745	RESPONSE REGULATOR receiver
GE376_23425	COG4895	conserved protein (DUF2196)
GE376_23430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GE376_23440	COG4509	Sortase family
GE376_23445	COG1120	ATPase activity
GE376_23460	COG5386	Cell surface protein
GE376_23470	COG5386	Cell surface protein
GE376_23475	COG1114	Component of the transport system for branched-chain amino acids
GE376_23480	COG1187	pseudouridine synthase activity
GE376_23490	COG1796	DNA polymerase
GE376_23490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE376_23495	COG1286	toxin biosynthetic process
GE376_23540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE376_23550	COG1418	mRNA catabolic process
GE376_23570	COG2814	Major facilitator Superfamily
GE376_23575	COG1566	PFAM secretion protein HlyD family protein
GE376_23580	COG1309	transcriptional regulator
GE376_23585	COG1363	Peptidase, m42
GE376_23610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE376_23625	COG1484	DNA-dependent DNA replication
GE376_23630	COG3611	Membrane attachment protein
GE376_23640	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GE376_23645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE376_23650	COG0237	dephospho-CoA kinase activity
GE376_23655	COG1971	Probably functions as a manganese efflux pump
GE376_23665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_23665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_23670	COG5002	protein histidine kinase activity
GE376_23675	COG0745	RESPONSE REGULATOR receiver
GE376_23695	COG0538	isocitrate dehydrogenase activity
GE376_23700	COG0372	Belongs to the citrate synthase family
GE376_23720	COG0628	permease
GE376_23725	COG3030	protein affecting phage T7 exclusion by the F plasmid
GE376_23750	COG1725	Transcriptional regulator
GE376_23755	COG0281	malic enzyme
GE376_23760	COG0587	DNA-directed DNA polymerase activity
GE376_23775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GE376_23790	COG4109	DRTGG domain
GE376_23800	COG0006	proline dipeptidase activity
GE376_23845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_23850	COG0662	Cupin 2, conserved barrel domain protein
GE376_23865	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_23870	COG0589	response to stress
GE376_23905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_23930	COG0827	DNA restriction-modification system
GE376_23935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GE376_23940	COG3874	Sporulation protein YtfJ
GE376_23955	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GE376_23965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_23980	COG1104	cysteine desulfurase activity
GE376_23990	COG0583	DNA-binding transcription factor activity
GE376_23995	COG0697	spore germination
GE376_24000	COG1309	transcriptional regulator
GE376_24005	COG1956	GAF domain-containing protein
GE376_24010	COG0626	cystathionine gamma-synthase activity
GE376_24040	COG1595	DNA-templated transcription, initiation
GE376_24050	COG0110	maltose O-acetyltransferase activity
GE376_24055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_24060	COG0454	-acetyltransferase
GE376_24065	COG0517	IMP dehydrogenase activity
GE376_24070	COG0123	including yeast histone deacetylase and acetoin utilization protein
GE376_24075	COG2267	carboxylic ester hydrolase activity
GE376_24085	COG0745	RESPONSE REGULATOR receiver
GE376_24090	COG5002	protein histidine kinase activity
GE376_24095	COG0666	response to abiotic stimulus
GE376_24125	COG1609	Transcriptional regulator
GE376_24135	COG4851	CamS sex pheromone cAM373 precursor
GE376_24140	COG3118	belongs to the thioredoxin family
GE376_24150	COG2309	aminopeptidase activity
GE376_24170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_24175	COG0697	spore germination
GE376_24180	COG0789	Transcriptional regulator
GE376_24195	COG1674	ftsk spoiiie
GE376_24200	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_24210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE376_24220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_24225	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GE376_24230	COG1363	Peptidase, m42
GE376_24240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_24255	COG0510	thiamine kinase activity
GE376_24260	COG1523	belongs to the glycosyl hydrolase 13 family
GE376_24270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_24275	COG1349	DNA-binding transcription factor activity
GE376_24280	COG1187	pseudouridine synthase activity
GE376_24285	COG2244	polysaccharide biosynthetic process
GE376_24290	COG2081	HI0933 family
GE376_24295	COG2814	Major facilitator Superfamily
GE376_24305	COG3832	glyoxalase III activity
GE376_24330	COG1329	Transcriptional regulator
GE376_24355	COG0314	molybdopterin synthase activity
GE376_24360	COG1763	Mo-molybdopterin cofactor biosynthetic process
GE376_24365	COG0303	'Molybdopterin
GE376_24375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_24380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GE376_24405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_24415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GE376_24455	COG2814	Major facilitator Superfamily
GE376_24460	COG0475	glutathione-regulated potassium exporter activity
GE376_24465	COG0490	domain, Protein
GE376_24470	COG0582	viral genome integration into host DNA
GE376_24485	COG1136	(ABC) transporter
GE376_24520	COG1242	4 iron, 4 sulfur cluster binding
GE376_24525	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GE376_24530	COG1131	(ABC) transporter
GE376_24540	COG1794	racemase activity, acting on amino acids and derivatives
GE376_24565	COG2267	carboxylic ester hydrolase activity
GE376_24570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GE376_24575	COG0671	phosphoesterase, PA-phosphatase related
GE376_24580	COG0438	transferase activity, transferring glycosyl groups
GE376_24660	COG5002	protein histidine kinase activity
GE376_24665	COG3852	Histidine kinase
GE376_24675	COG2267	carboxylic ester hydrolase activity
GE376_24680	COG1368	sulfuric ester hydrolase activity
GE376_24705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_24710	COG1116	anion transmembrane transporter activity
GE376_24715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_24740	COG0494	nUDIX hydrolase
GE376_24780	COG0288	reversible hydration of carbon dioxide
GE376_24785	COG1271	oxidase subunit
GE376_24790	COG1294	oxidase, subunit
GE376_24805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_24830	COG1842	Phage shock protein A
GE376_24855	COG3859	Proton-coupled thiamine transporter YuaJ
GE376_24860	COG5002	protein histidine kinase activity
GE376_24865	COG0745	RESPONSE REGULATOR receiver
GE376_24895	COG1597	lipid kinase activity
GE376_24905	COG0577	efflux transmembrane transporter activity
GE376_24910	COG1136	(ABC) transporter
GE376_24925	COG0586	Pfam SNARE associated Golgi protein
GE376_24935	COG0577	efflux transmembrane transporter activity
GE376_24940	COG1136	(ABC) transporter
GE376_24945	COG3708	Transcriptional regulator
GE376_24945	COG2207	Transcriptional regulator
GE376_24960	COG0640	Transcriptional regulator
GE376_24965	COG0745	RESPONSE REGULATOR receiver
GE376_24970	COG2205	protein histidine kinase activity
GE376_24975	COG0577	efflux transmembrane transporter activity
GE376_24980	COG0577	efflux transmembrane transporter activity
GE376_24985	COG1136	(ABC) transporter
GE376_24990	COG0577	efflux transmembrane transporter activity
GE376_25035	COG3964	amidohydrolase
GE376_25055	COG4948	Mandelate Racemase Muconate Lactonizing
GE376_25065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GE376_25070	COG0596	Alpha beta hydrolase
GE376_25080	COG1169	isochorismate synthase
GE376_25085	COG1575	Belongs to the MenA family. Type 1 subfamily
GE376_25090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GE376_25095	COG1278	Cold shock
GE376_25115	COG0058	SHG alpha-glucan phosphorylase activity
GE376_25125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE376_25145	COG1404	Belongs to the peptidase S8 family
GE376_25285	COG1285	pathogenesis
GE376_25290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GE376_25310	COG2155	Conserved Protein
GE376_25315	COG1098	S1 RNA binding domain
GE376_25320	COG0436	Aminotransferase
GE376_25325	COG1522	sequence-specific DNA binding
GE376_25330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE376_25335	COG2267	carboxylic ester hydrolase activity
GE376_25345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GE376_25360	COG5018	Exonuclease
GE376_25365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_25380	COG0423	glycine-tRNA ligase activity
GE376_25385	COG2050	protein possibly involved in aromatic compounds catabolism
GE376_25395	COG1268	BioY protein
GE376_25400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE376_25405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE376_25425	COG2076	Multidrug Resistance protein
GE376_25430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GE376_25440	COG3584	3D domain protein
GE376_25455	COG1252	NADH dehydrogenase
GE376_25470	COG3708	Transcriptional regulator
GE376_25485	COG1683	Conserved Protein
GE376_25515	COG0316	Belongs to the HesB IscA family
GE376_25530	COG1252	NADH dehydrogenase
GE376_25540	COG2274	protein secretion by the type I secretion system
GE376_25545	COG0390	transport system, permease component
GE376_25550	COG2824	Alkylphosphonate utilization operon protein PhnA
GE376_25570	COG4837	Protein of unknown function (DUF1462)
GE376_25575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GE376_25585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GE376_25590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE376_25610	COG1358	cellular component organization or biogenesis
GE376_25625	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_25630	COG0647	UMP catabolic process
GE376_25640	COG2445	Protein of unknown function DUF86
GE376_25645	COG1494	fructose-1,6-bisphosphatase
GE376_25665	COG4470	Protein conserved in bacteria
GE376_25675	COG0789	Transcriptional regulator
GE376_25680	COG4377	Putative membrane peptidase family (DUF2324)
GE376_25715	COG0739	heme binding
GE376_25725	COG3377	Domain of unknown function (DUF1805)
GE376_25730	COG0737	Belongs to the 5'-nucleotidase family
GE376_25735	COG0719	Fe-S assembly protein
GE376_25740	COG0822	iron-sulfur transferase activity
GE376_25745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE376_25750	COG0719	Fe-S assembly protein
GE376_25755	COG0396	ATPase activity
GE376_25760	COG1464	Belongs to the NlpA lipoprotein family
GE376_25765	COG1464	Belongs to the NlpA lipoprotein family
GE376_25770	COG2011	ABC-type metal ion transport system permease component
GE376_25785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_25790	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GE376_25800	COG1393	Belongs to the ArsC family
GE376_25840	COG0039	L-malate dehydrogenase activity
GE376_25860	COG1309	transcriptional regulator
GE376_25865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_25870	COG1960	acyl-CoA dehydrogenase activity
GE376_25875	COG0183	Belongs to the thiolase family
GE376_25880	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_25880	COG1024	Enoyl-CoA hydratase
GE376_25890	COG1686	Belongs to the peptidase S11 family
GE376_25905	COG0011	TIGRFAM Protein of
GE376_25910	COG0840	transmembrane signaling receptor activity
GE376_25925	COG2814	Major facilitator Superfamily
GE376_25930	COG0531	amino acid
GE376_25955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_25995	COG0586	Pfam SNARE associated Golgi protein
GE376_26005	COG1376	ErfK ybiS ycfS ynhG family protein
GE376_26010	COG0745	RESPONSE REGULATOR receiver
GE376_26015	COG5002	protein histidine kinase activity
GE376_26045	COG0840	transmembrane signaling receptor activity
GE376_26050	COG2151	metal-sulfur cluster biosynthetic enzyme
GE376_26055	COG3227	Zinc metalloprotease (Elastase)
GE376_26075	COG0586	Pfam SNARE associated Golgi protein
GE376_26080	COG0475	glutathione-regulated potassium exporter activity
GE376_26085	COG0490	domain, Protein
GE376_26090	COG1115	amino acid carrier protein
GE376_26095	COG0783	Belongs to the Dps family
GE376_26105	COG2318	DinB family
GE376_26115	COG1611	Belongs to the LOG family
GE376_26125	COG1528	Iron-storage protein
GE376_26130	COG2311	Membrane
GE376_26135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_26140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_26145	COG1115	amino acid carrier protein
GE376_26150	COG1115	amino acid carrier protein
GE376_26155	COG2910	NAD(P)H-binding
GE376_26170	COG0656	L-ascorbic acid biosynthetic process
GE376_26175	COG2814	Major facilitator Superfamily
GE376_26180	COG1733	regulation of RNA biosynthetic process
GE376_26190	COG1252	NADH dehydrogenase
GE376_26195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GE376_26240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_26245	COG3223	Belongs to the PsiE family
GE376_26255	COG1335	isochorismatase
GE376_26260	COG1522	sequence-specific DNA binding
GE376_26330	COG0557	exoribonuclease II activity
GE376_26335	COG1647	Serine aminopeptidase, S33
GE376_26340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE376_26345	COG1346	cytolysis
GE376_26380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE376_26395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GE376_26405	COG1668	transmembrane transport
GE376_26410	COG4152	abc transporter atp-binding protein
GE376_26415	COG4585	Histidine kinase
GE376_26445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_26460	COG2323	membrane
GE376_26470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_26480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GE376_26490	COG1051	belongs to the nudix hydrolase family
GE376_26500	COG0492	ferredoxin-NADP+ reductase activity
GE376_26505	COG0457	Tetratricopeptide repeat
GE376_26510	COG0110	maltose O-acetyltransferase activity
GE376_26530	COG1950	PFAM Membrane protein of
GE376_26535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GE376_26555	COG0789	Transcriptional regulator
GE376_26580	COG0583	DNA-binding transcription factor activity
GE376_26590	COG0655	NAD(P)H dehydrogenase (quinone) activity
GE376_26605	COG1132	(ABC) transporter
GE376_26610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_26615	COG3409	Peptidoglycan-binding domain 1 protein
GE376_26615	COG0793	Belongs to the peptidase S41A family
GE376_26620	COG2177	Part of the ABC transporter FtsEX involved in
GE376_26625	COG2884	Cell division ATP-binding protein ftsE
GE376_26645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GE376_26650	COG1278	Cold shock
GE376_26660	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GE376_26665	COG1388	LysM domain
GE376_26665	COG0791	NLP P60 protein
GE376_26670	COG1733	regulation of RNA biosynthetic process
GE376_26675	COG1307	EDD domain protein, DegV family
GE376_26680	COG1739	Uncharacterized protein family UPF0029
GE376_26685	COG1316	TRANSCRIPTIONal
GE376_26690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GE376_26695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE376_26700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE376_26710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GE376_26710	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GE376_26730	COG1486	melibiose metabolic process
GE376_26735	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_26740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_26760	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_26770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_26775	COG1301	dicarboxylic acid transport
GE376_26790	COG1511	domain protein
GE376_26795	COG0583	DNA-binding transcription factor activity
GE376_26800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GE376_26805	COG1271	oxidase subunit
GE376_26810	COG1294	oxidase, subunit
GE376_26815	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_26845	COG1620	l-lactate permease
GE376_26855	COG2389	metal-binding protein
GE376_26870	COG1368	sulfuric ester hydrolase activity
GE376_26880	COG1388	LysM domain
GE376_26880	COG0791	NLP P60 protein
GE376_26885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_26895	COG1215	transferase activity, transferring glycosyl groups
GE376_26900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_26910	COG3584	3D domain protein
GE376_26910	COG1388	LysM domain
GE376_26935	COG4715	Zinc finger, swim domain protein
GE376_26940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_26970	COG1191	sigma factor activity
GE376_26980	COG0577	efflux transmembrane transporter activity
GE376_26985	COG1136	(ABC) transporter
GE376_27020	COG5002	protein histidine kinase activity
GE376_27025	COG0745	RESPONSE REGULATOR receiver
GE376_27030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE376_27050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE376_27055	COG2244	polysaccharide biosynthetic process
GE376_27075	COG0438	transferase activity, transferring glycosyl groups
GE376_27080	COG0438	transferase activity, transferring glycosyl groups
GE376_27095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE376_27100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_27105	COG1086	Polysaccharide biosynthesis protein
GE376_27110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE376_27115	COG4464	protein tyrosine phosphatase activity
GE376_27120	COG0489	protein tyrosine kinase activity
GE376_27125	COG3944	biosynthesis protein
GE376_27130	COG0489	protein tyrosine kinase activity
GE376_27145	COG1609	Transcriptional regulator
GE376_27155	COG0739	heme binding
GE376_27170	COG3279	Response regulator of the LytR AlgR family
GE376_27175	COG2385	sporulation resulting in formation of a cellular spore
GE376_27180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GE376_27190	COG4836	Membrane
GE376_27195	COG1007	ATP synthesis coupled electron transport
GE376_27200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GE376_27205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GE376_27215	COG0839	Belongs to the complex I subunit 6 family
GE376_27235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GE376_27250	COG3300	MHYT domain
GE376_27250	COG5001	Diguanylate cyclase
GE376_27305	COG0356	it plays a direct role in the translocation of protons across the membrane
GE376_27345	COG0698	ribose 5-phosphate isomerase
GE376_27355	COG2190	(PTS) system
GE376_27360	COG2259	Doxx family
GE376_27365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE376_27380	COG0009	L-threonylcarbamoyladenylate synthase
GE376_27400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GE376_27420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GE376_27425	COG1494	fructose-1,6-bisphosphatase
GE376_27445	COG4821	SIS domain
GE376_27455	COG3343	RNA polymerase activity
GE376_27465	COG1960	acyl-CoA dehydrogenase activity
GE376_27470	COG1960	acyl-CoA dehydrogenase activity
GE376_27475	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_27485	COG2181	nitrate reductase activity
GE376_27485	COG0247	lactate metabolic process
GE376_27490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_27500	COG3300	MHYT domain
GE376_27500	COG5001	Diguanylate cyclase
GE376_27515	COG3227	Zinc metalloprotease (Elastase)
GE376_27520	COG2197	response regulator
GE376_27525	COG4585	Histidine kinase
GE376_27530	COG0842	Transport permease protein
GE376_27535	COG1131	(ABC) transporter
GE376_27540	COG0024	Methionine aminopeptidase
GE376_27550	COG2234	aminopeptidase activity
GE376_27570	COG1595	DNA-templated transcription, initiation
GE376_27580	COG4506	Protein conserved in bacteria
GE376_27585	COG1619	proteins homologs of microcin C7 resistance protein MccF
GE376_27605	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GE376_27610	COG2814	Major facilitator Superfamily
GE376_27615	COG0789	Transcriptional regulator
GE376_27620	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_27625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_27635	COG1994	Peptidase M50
GE376_27645	COG1078	dGTPase activity
GE376_27650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_27655	COG1120	ATPase activity
GE376_27660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_27665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_27685	COG0280	phosphate acetyltransferase
GE376_27700	COG3773	Cell wall hydrolase
GE376_27710	COG2363	Small membrane protein
GE376_27720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GE376_27725	COG2233	PERMEase
GE376_27730	COG0561	phosphatase activity
GE376_27735	COG2814	Major facilitator Superfamily
GE376_27745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE376_27750	COG1131	(ABC) transporter
GE376_27755	COG2755	lipolytic protein G-D-S-L family
GE376_27760	COG1609	Transcriptional regulator
GE376_27770	COG0460	homoserine dehydrogenase
GE376_27790	COG1011	Hydrolase
GE376_27795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_27805	COG2197	response regulator
GE376_27810	COG4585	Histidine kinase
GE376_27810	COG2203	Gaf domain
GE376_27815	COG0351	phosphomethylpyrimidine kinase
GE376_27820	COG3706	GGDEF domain
GE376_27825	COG2879	small protein
GE376_27830	COG1966	Carbon starvation protein
GE376_27835	COG3279	Response regulator of the LytR AlgR family
GE376_27840	COG0477	Major facilitator Superfamily
GE376_27850	COG0438	transferase activity, transferring glycosyl groups
GE376_27865	COG0840	transmembrane signaling receptor activity
GE376_27875	COG1607	acyl-coa hydrolase
GE376_27880	COG1216	Glycosyl transferase, family 2
GE376_27890	COG1216	Glycosyl transferase, family 2
GE376_27910	COG0488	(ABC) transporter
GE376_27915	COG1696	Membrane protein involved in D-alanine export
GE376_27925	COG1309	transcriptional regulator
GE376_27930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE376_27935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_27935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_27940	COG0628	permease
GE376_27960	COG3275	phosphorelay sensor kinase activity
GE376_27965	COG2814	Major facilitator Superfamily
GE376_27970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_27975	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GE376_28010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE376_28015	COG1272	protein, Hemolysin III
GE376_28035	COG1164	Oligoendopeptidase f
GE376_28045	COG5002	protein histidine kinase activity
GE376_28060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_28065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE376_28070	COG4853	Protein conserved in bacteria
GE376_28080	COG5002	protein histidine kinase activity
GE376_28085	COG0745	RESPONSE REGULATOR receiver
GE376_28115	COG0305	Participates in initiation and elongation during chromosome replication
GE376_28125	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GE376_28130	COG4241	membrane
GE376_28140	COG0629	single-stranded DNA binding
GE376_28150	COG0012	GTP binding
GE376_28155	COG4481	Protein conserved in bacteria
GE376_28160	COG0668	transmembrane transport
GE376_28170	COG1475	DNA binding
GE376_28175	COG1192	Involved in chromosome partitioning
GE376_28200	COG1847	R3H domain protein
GE376_28205	COG0706	membrane insertase activity
GE376_28220	COG0561	phosphatase activity
GE376_28225	COG0673	inositol 2-dehydrogenase activity
GE376_28230	COG0738	Major facilitator superfamily
GE376_28250	COG1475	DNA binding
GE376_28345	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GE376_28350	COG1131	(ABC) transporter
GE376_28375	COG3848	Pyruvate phosphate dikinase
GE376_28375	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_28380	COG3848	Pyruvate phosphate dikinase
GE376_28380	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_28415	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE376_28515	COG3344	reverse transcriptase
GE376_28535	COG0494	nUDIX hydrolase
GE376_28585	COG0463	Glycosyl transferase, family 2
GE376_28590	COG0463	Glycosyl transferase, family 2
GE376_28595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GE376_28605	COG1088	dTDP-glucose 4,6-dehydratase activity
GE376_28610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_28615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GE376_28630	COG2089	acid synthase
GE376_28645	COG4641	Protein conserved in bacteria
GE376_28670	COG1309	transcriptional regulator
GE376_28675	COG2814	Major facilitator Superfamily
GE376_28695	COG5002	protein histidine kinase activity
GE376_28735	COG4974	Belongs to the 'phage' integrase family
GE376_28755	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_28775	COG1876	peptidase activity
GE376_28785	COG2239	Acts as a magnesium transporter
GE376_28795	COG0772	Belongs to the SEDS family
GE376_28800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_28815	COG1802	Transcriptional regulator
GE376_28820	COG0697	spore germination
GE376_28840	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GE376_28855	COG0076	glutamate decarboxylase activity
GE376_28900	COG3961	Belongs to the TPP enzyme family
GE376_28910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_28910	COG0723	plastoquinol--plastocyanin reductase activity
GE376_28915	COG2124	cytochrome p450
GE376_28925	COG1923	regulation of RNA biosynthetic process
GE376_28940	COG0840	transmembrane signaling receptor activity
GE376_28945	COG2184	nucleotidyltransferase activity
GE376_28960	COG1522	sequence-specific DNA binding
GE376_28965	COG0531	amino acid
GE376_28985	COG1923	regulation of RNA biosynthetic process
GE376_29005	COG3591	Belongs to the peptidase S1B family
GE376_29045	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_29060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_29070	COG3104	oligopeptide transport
GE376_29090	COG2423	ornithine cyclodeaminase activity
GE376_29105	COG2091	lysine biosynthetic process via aminoadipic acid
GE376_29135	COG2366	antibiotic biosynthetic process
GE376_29140	COG2211	Major facilitator Superfamily
GE376_29150	COG0697	spore germination
GE376_29155	COG1802	Transcriptional regulator
GE376_29165	COG0697	spore germination
GE376_29205	COG2002	toxin-antitoxin pair type II binding
GE376_29210	COG0776	regulation of translation
GE376_29225	COG0776	regulation of translation
GE376_29230	COG5504	Zn-dependent protease
GE376_29235	COG0789	Transcriptional regulator
GE376_29290	COG2329	Antibiotic biosynthesis monooxygenase
GE376_29320	COG2311	Membrane
GE376_29360	COG1329	Transcriptional regulator
GE376_29380	COG1278	Cold shock
GE376_29395	COG1131	(ABC) transporter
GE376_29400	COG1725	Transcriptional regulator
GE376_29505	COG3331	DNA recombination
GE376_29545	COG0322	excinuclease ABC activity
GE376_29825	COG3693	PFAM glycoside hydrolase, family 10
GE376_29850	COG2020	methyltransferase activity
GE376_29865	COG2318	DinB family
GE376_29975	COG0457	Tetratricopeptide repeat
GE376_29985	COG3584	3D domain protein
GE376_29985	COG3583	domain protein
GE376_29990	COG1388	LysM domain
GE376_29990	COG0791	NLP P60 protein
GE376_29995	COG0741	lytic transglycosylase activity
GE376_29995	COG1196	nuclear chromosome segregation
GE376_29995	COG0739	heme binding
GE376_30035	COG2234	aminopeptidase activity
GE376_30040	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_30075	COG0739	heme binding
GE376_30080	COG1388	LysM domain
GE376_30080	COG3409	Peptidoglycan-binding domain 1 protein
GE376_30080	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_30095	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_30170	COG1396	sequence-specific DNA binding
GE376_30185	COG0726	polysaccharide deacetylase
GE376_30190	COG1309	transcriptional regulator
GE376_30195	COG0367	asparagine synthase
GE376_30260	COG3409	Peptidoglycan-binding domain 1 protein
GE376_30260	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_30265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GE376_30305	COG1136	(ABC) transporter
GE376_30370	COG0457	Tetratricopeptide repeat
GE376_30400	COG0457	Tetratricopeptide repeat
GE376_30515	COG1201	RNA secondary structure unwinding
GE376_30540	COG1396	sequence-specific DNA binding
GE376_30590	COG1396	sequence-specific DNA binding
GE376_30590	COG3800	Transcriptional regulator
GE376_30660	COG1024	Enoyl-CoA hydratase
GE376_30665	COG1216	Glycosyl transferase, family 2
GE376_30665	COG0463	Glycosyl transferase, family 2
GE376_30680	COG1396	sequence-specific DNA binding
GE376_30710	COG0667	Aldo Keto reductase
GE376_30730	COG0542	response to heat
GE376_30735	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_30735	COG3321	synthase
GE376_30735	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_30735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_30735	COG0300	oxidoreductase activity
GE376_30735	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_30735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_30735	COG0300	oxidoreductase activity
GE376_30735	COG3321	synthase
GE376_30735	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_30755	COG1960	acyl-CoA dehydrogenase activity
GE376_30770	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_30775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_30790	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_30790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_30790	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_30790	COG3321	synthase
GE376_30790	COG0300	oxidoreductase activity
GE376_30795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_30830	COG1609	Transcriptional regulator
GE376_30835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_30850	COG1328	CTP reductase activity
GE376_30850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE376_30865	COG0426	domain, Protein
GE376_30870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_30875	COG1773	rubredoxin
GE376_30885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_30900	COG4990	cell redox homeostasis
GE376_30905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_30910	COG2116	formate transmembrane transporter activity
GE376_30925	COG0531	amino acid
GE376_30940	COG0531	amino acid
GE376_30945	COG0657	acetylesterase activity
GE376_30975	COG2070	2-Nitropropane dioxygenase
GE376_30985	COG5002	protein histidine kinase activity
GE376_30990	COG0745	RESPONSE REGULATOR receiver
GE376_30995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_31000	COG0577	efflux transmembrane transporter activity
GE376_31005	COG1136	(ABC) transporter
GE376_31030	COG0823	Involved in the tonB-independent uptake of proteins
GE376_31045	COG1131	(ABC) transporter
GE376_31065	COG3979	chitinase
GE376_31075	COG3604	Transcriptional regulator
GE376_31080	COG2376	Dihydroxyacetone kinase
GE376_31090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_31095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE376_31105	COG3715	PTS system
GE376_31110	COG3716	PTS system mannose fructose sorbose family IID component
GE376_31130	COG1846	Transcriptional regulator
GE376_31135	COG0726	polysaccharide deacetylase
GE376_31150	COG2002	toxin-antitoxin pair type II binding
GE376_31160	COG1923	regulation of RNA biosynthetic process
GE376_31180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_31180	COG0456	acetyltransferase
GE376_31200	COG0583	DNA-binding transcription factor activity
GE376_31205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_31230	COG0745	RESPONSE REGULATOR receiver
GE376_31235	COG2205	protein histidine kinase activity
GE376_31240	COG1136	(ABC) transporter
GE376_31245	COG0577	efflux transmembrane transporter activity
GE376_31285	COG0741	lytic transglycosylase activity
GE376_31290	COG0772	Belongs to the SEDS family
GE376_31320	COG0726	polysaccharide deacetylase
GE376_31395	COG0697	spore germination
GE376_31405	COG1114	Component of the transport system for branched-chain amino acids
GE376_31410	COG1115	amino acid carrier protein
GE376_31415	COG2066	Belongs to the glutaminase family
GE376_31440	COG3754	Rhamnan synthesis protein F
GE376_31445	COG1131	(ABC) transporter
GE376_31450	COG0842	Transport permease protein
GE376_31465	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_31475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GE376_31490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GE376_31495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE376_31515	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE376_31555	COG2040	homocysteine
GE376_31560	COG0833	amino acid
GE376_31565	COG1482	cell wall glycoprotein biosynthetic process
GE376_31570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_31570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_31570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_31575	COG3711	transcriptional antiterminator
GE376_31575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_31610	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE376_31615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_31620	COG3271	cysteine-type peptidase activity
GE376_31620	COG2274	protein secretion by the type I secretion system
GE376_31630	COG3344	reverse transcriptase
GE376_31660	COG0697	spore germination
GE376_31705	COG2197	response regulator
GE376_31730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_31730	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_31785	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GE376_31820	COG3011	Protein conserved in bacteria
GE376_31835	COG1136	(ABC) transporter
GE376_31865	COG0726	polysaccharide deacetylase
GE376_31895	COG1132	(ABC) transporter
GE376_31905	COG1309	transcriptional regulator
GE376_31910	COG2357	RelA SpoT domain protein
GE376_31925	COG2814	Major facilitator Superfamily
GE376_31950	COG0640	Transcriptional regulator
GE376_31960	COG2814	Major facilitator Superfamily
GE376_31965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GE376_31995	COG1408	metallophosphoesterase
GE376_32030	COG2732	(Barnase) inhibitor
GE376_32050	COG2002	toxin-antitoxin pair type II binding
GE376_32090	COG1012	belongs to the aldehyde dehydrogenase family
GE376_32090	COG1454	alcohol dehydrogenase
GE376_32120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE376_32125	COG0463	Glycosyl transferase, family 2
GE376_32130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_32135	COG2274	protein secretion by the type I secretion system
GE376_32135	COG3271	cysteine-type peptidase activity
GE376_32150	COG0582	viral genome integration into host DNA
GE376_32165	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_32195	COG0582	viral genome integration into host DNA